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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for EPAS1_BCL3

Z-value: 3.61

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Transcription factors associated with EPAS1_BCL3

Gene Symbol Gene ID Gene Info
ENSG00000116016.14 endothelial PAS domain protein 1
ENSG00000069399.15 BCL3 transcription coactivator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EPAS1hg38_v1_chr2_+_46297397_462974140.782.3e-02Click!
BCL3hg38_v1_chr19_+_44748673_447487490.531.8e-01Click!

Activity profile of EPAS1_BCL3 motif

Sorted Z-values of EPAS1_BCL3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_57628507 5.11 ENST00000456916.5
ENST00000567154.5
ENST00000388813.9
ENST00000562558.6
ENST00000566271.6
ENST00000563374.5
ENST00000673126.2
ENST00000562631.7
ENST00000568234.5
ENST00000565770.5
ENST00000566164.5
adhesion G protein-coupled receptor G1
chr5_+_53480619 3.79 ENST00000396947.7
ENST00000256759.8
follistatin
chr20_+_46008900 3.47 ENST00000372330.3
matrix metallopeptidase 9
chr16_-_31135699 3.42 ENST00000317508.11
ENST00000568261.5
ENST00000567797.1
serine protease 8
chr16_+_57628684 3.28 ENST00000567397.5
ENST00000568979.5
ENST00000672974.1
adhesion G protein-coupled receptor G1
chr16_+_22814154 3.17 ENST00000261374.4
heparan sulfate-glucosamine 3-sulfotransferase 2
chr8_-_133297092 3.13 ENST00000522890.5
ENST00000675983.1
ENST00000518176.5
ENST00000323851.13
ENST00000522476.5
ENST00000518066.5
ENST00000521544.5
ENST00000674605.1
ENST00000518480.5
ENST00000523892.5
N-myc downstream regulated 1
chr2_+_102001966 3.06 ENST00000457817.5
interleukin 1 receptor type 2
chr7_+_121873089 2.66 ENST00000651065.1
protein tyrosine phosphatase receptor type Z1
chr3_-_134029914 2.62 ENST00000493729.5
ENST00000310926.11
solute carrier organic anion transporter family member 2A1
chr4_+_40196907 2.54 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chr7_+_121873478 2.52 ENST00000651320.1
protein tyrosine phosphatase receptor type Z1
chr11_+_10450289 2.50 ENST00000444303.6
adenosine monophosphate deaminase 3
chr5_+_167754918 2.45 ENST00000519204.5
teneurin transmembrane protein 2
chr7_+_121873152 2.42 ENST00000650826.1
ENST00000650728.1
ENST00000393386.7
ENST00000651390.1
ENST00000651842.1
ENST00000650681.1
protein tyrosine phosphatase receptor type Z1
chr15_+_40239420 2.38 ENST00000560346.5
p21 (RAC1) activated kinase 6
chr3_-_116444983 2.37 ENST00000333617.8
limbic system associated membrane protein
chr15_+_40239857 2.26 ENST00000260404.8
p21 (RAC1) activated kinase 6
chr7_+_121873317 2.19 ENST00000651863.1
ENST00000652298.1
ENST00000449182.1
protein tyrosine phosphatase receptor type Z1
chr1_+_152514474 2.12 ENST00000368790.4
cysteine rich C-terminal 1
chr2_-_237590660 2.08 ENST00000409576.1
RAB17, member RAS oncogene family
chr6_-_136526177 2.03 ENST00000617204.4
microtubule associated protein 7
chr11_+_10450627 1.96 ENST00000396554.7
ENST00000524866.5
adenosine monophosphate deaminase 3
chr6_-_136526654 1.94 ENST00000611373.1
microtubule associated protein 7
chr6_-_136526472 1.89 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr18_+_63587336 1.85 ENST00000344731.10
serpin family B member 13
chr4_+_40197023 1.83 ENST00000381799.10
ras homolog family member H
chr18_+_63587297 1.78 ENST00000269489.9
serpin family B member 13
chr11_-_125496122 1.74 ENST00000527534.1
ENST00000278919.8
ENST00000366139.3
fasciculation and elongation protein zeta 1
chr18_+_63777773 1.73 ENST00000447428.5
ENST00000546027.5
serpin family B member 7
chr17_+_75754618 1.63 ENST00000584939.1
integrin subunit beta 4
chr19_-_42877988 1.56 ENST00000597058.1
pregnancy specific beta-1-glycoprotein 1
chr12_-_85836372 1.54 ENST00000361228.5
Ras association domain family member 9
chr16_+_82035245 1.53 ENST00000199936.9
hydroxysteroid 17-beta dehydrogenase 2
chr11_-_79441016 1.52 ENST00000278550.12
teneurin transmembrane protein 4
chr3_-_56775657 1.50 ENST00000413728.6
Rho guanine nucleotide exchange factor 3
chr6_-_40587314 1.49 ENST00000338305.7
leucine rich repeat and fibronectin type III domain containing 2
chr6_+_1312090 1.45 ENST00000296839.5
forkhead box Q1
chr3_+_187024614 1.42 ENST00000416235.6
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr18_-_55423757 1.41 ENST00000675707.1
transcription factor 4
chr2_+_205683109 1.41 ENST00000357118.8
ENST00000272849.7
ENST00000412873.2
neuropilin 2
chr2_-_237590694 1.40 ENST00000264601.8
ENST00000411462.5
ENST00000409822.1
RAB17, member RAS oncogene family
chr16_+_71626149 1.38 ENST00000567566.1
MARVEL domain containing 3
chr20_+_9069076 1.37 ENST00000378473.9
phospholipase C beta 4
chr1_+_153031195 1.35 ENST00000307098.5
small proline rich protein 1B
chr10_+_110207587 1.35 ENST00000332674.9
ENST00000453116.5
MAX interactor 1, dimerization protein
chr8_+_27491125 1.33 ENST00000517536.5
ENST00000521400.6
ENST00000521780.5
ENST00000380476.7
ENST00000518379.5
ENST00000521684.1
epoxide hydrolase 2
chr8_+_100158029 1.31 ENST00000251809.4
sperm associated antigen 1
chr17_-_41518878 1.27 ENST00000254043.8
keratin 15
chr14_+_70641896 1.27 ENST00000256367.3
tetratricopeptide repeat domain 9
chr5_+_52989314 1.27 ENST00000296585.10
integrin subunit alpha 2
chr19_-_35513641 1.26 ENST00000339686.8
ENST00000447113.6
dermokine
chr11_-_108593738 1.26 ENST00000525344.5
ENST00000265843.9
exophilin 5
chr19_-_42594918 1.22 ENST00000244336.10
CEA cell adhesion molecule 8
chr16_+_71626175 1.22 ENST00000268485.8
ENST00000565261.1
ENST00000299952.4
MARVEL domain containing 3
chr7_-_41703062 1.22 ENST00000242208.5
inhibin subunit beta A
chr7_+_142511614 1.19 ENST00000390377.1
T cell receptor beta variable 7-7
chr20_+_52972347 1.17 ENST00000371497.10
teashirt zinc finger homeobox 2
chrX_+_17375194 1.17 ENST00000676302.1
NHS actin remodeling regulator
chrX_+_17375230 1.16 ENST00000380060.7
NHS actin remodeling regulator
chr1_-_206003385 1.15 ENST00000617070.5
RAB7B, member RAS oncogene family
chr20_-_38165261 1.14 ENST00000361475.7
transglutaminase 2
chr15_+_43693859 1.13 ENST00000413453.7
ENST00000415044.3
ENST00000626814.1
creatine kinase, mitochondrial 1A
chr15_+_43594027 1.13 ENST00000453733.5
ENST00000441322.6
ENST00000627381.1
creatine kinase, mitochondrial 1B
chr1_+_81800368 1.12 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr7_+_148339452 1.11 ENST00000463592.3
contactin associated protein 2
chr6_-_134052594 1.08 ENST00000275230.6
solute carrier family 2 member 12
chr3_+_113211459 1.07 ENST00000495514.5
BOC cell adhesion associated, oncogene regulated
chr6_+_12012304 1.06 ENST00000379388.7
ENST00000627968.2
ENST00000541134.5
HIVEP zinc finger 1
chr3_-_190120881 1.05 ENST00000319332.10
prolyl 3-hydroxylase 2
chr3_+_14402592 1.05 ENST00000622186.5
ENST00000621751.4
solute carrier family 6 member 6
chr1_+_46175079 1.05 ENST00000372003.6
tetraspanin 1
chr10_-_124450027 1.02 ENST00000451024.5
NK1 homeobox 2
chr3_-_193554799 1.00 ENST00000295548.3
ATPase 13A4
chr1_+_186828941 0.99 ENST00000367466.4
phospholipase A2 group IVA
chr6_+_28080565 0.98 ENST00000377325.2
ENST00000683778.1
zinc finger protein 165
chr11_+_76783349 0.97 ENST00000333090.5
tsukushi, small leucine rich proteoglycan
chr6_+_130421086 0.95 ENST00000545622.5
transmembrane protein 200A
chr6_-_136525961 0.95 ENST00000438100.6
microtubule associated protein 7
chr3_-_9249623 0.94 ENST00000383836.8
SLIT-ROBO Rho GTPase activating protein 3
chr12_-_84912783 0.93 ENST00000680892.1
ENST00000266682.10
ENST00000680714.1
ENST00000552192.5
solute carrier family 6 member 15
chr15_+_33310946 0.93 ENST00000415757.7
ENST00000634891.2
ENST00000389232.9
ENST00000622037.1
ryanodine receptor 3
chr3_-_171460063 0.93 ENST00000284483.12
ENST00000475336.5
ENST00000357327.9
ENST00000460047.5
ENST00000488470.5
ENST00000470834.5
TRAF2 and NCK interacting kinase
chr8_-_22133356 0.92 ENST00000680789.1
HR lysine demethylase and nuclear receptor corepressor
chr8_+_22057857 0.92 ENST00000517305.4
ENST00000265800.9
ENST00000517418.5
dematin actin binding protein
chr6_+_43770202 0.91 ENST00000372067.8
ENST00000672860.2
vascular endothelial growth factor A
chr2_-_31138041 0.91 ENST00000324589.9
polypeptide N-acetylgalactosaminyltransferase 14
chr1_+_202203721 0.90 ENST00000255432.11
leucine rich repeat containing G protein-coupled receptor 6
chr19_+_45340760 0.90 ENST00000585434.5
kinesin light chain 3
chr1_-_28193873 0.89 ENST00000305392.3
ENST00000539896.1
platelet activating factor receptor
chr19_+_45340736 0.87 ENST00000391946.7
kinesin light chain 3
chr7_+_86644829 0.87 ENST00000439827.1
ENST00000421579.1
glutamate metabotropic receptor 3
chr1_-_221742074 0.86 ENST00000366899.4
dual specificity phosphatase 10
chr3_-_12759224 0.84 ENST00000314124.12
ENST00000435218.6
ENST00000435575.5
transmembrane protein 40
chr4_+_152936315 0.83 ENST00000511601.6
FH2 domain containing 1
chr11_-_72722302 0.83 ENST00000334211.12
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr12_-_27971970 0.82 ENST00000395872.5
ENST00000201015.8
parathyroid hormone like hormone
chr17_-_43545636 0.82 ENST00000393664.6
ETS variant transcription factor 4
chr10_+_110226805 0.82 ENST00000651495.1
ENST00000652506.1
ENST00000651811.1
ENST00000651167.1
ENST00000651516.1
ENST00000651467.1
ENST00000651004.1
ENST00000650843.1
ENST00000650644.1
ENST00000650696.1
ENST00000652604.1
ENST00000652463.1
ENST00000650810.1
ENST00000650952.1
ENST00000652028.1
ENST00000651866.1
ENST00000651848.1
ENST00000442296.5
ENST00000369612.1
MAX interactor 1, dimerization protein
chr16_-_68236069 0.82 ENST00000473183.7
ENST00000565858.5
epithelial splicing regulatory protein 2
chr1_-_26360050 0.81 ENST00000475866.3
crystallin beta-gamma domain containing 2
chr17_-_43545707 0.80 ENST00000545089.5
ETS variant transcription factor 4
chr12_-_6631632 0.79 ENST00000431922.1
lysophosphatidic acid receptor 5
chr1_+_15152522 0.77 ENST00000428417.5
transmembrane protein 51
chr1_+_15152558 0.76 ENST00000376014.7
ENST00000451326.6
transmembrane protein 51
chr1_+_174799895 0.76 ENST00000489615.5
RAB GTPase activating protein 1 like
chr12_-_6375556 0.75 ENST00000228916.7
sodium channel epithelial 1 subunit alpha
chr8_+_122781621 0.74 ENST00000314393.6
zinc fingers and homeoboxes 2
chr14_-_53953415 0.74 ENST00000559501.1
ENST00000558984.1
bone morphogenetic protein 4
chr2_+_237566574 0.74 ENST00000165524.1
prolactin releasing hormone
chr12_+_4269771 0.73 ENST00000676411.1
cyclin D2
chr3_+_113211539 0.72 ENST00000682979.1
ENST00000485230.5
BOC cell adhesion associated, oncogene regulated
chr22_-_37149900 0.72 ENST00000216223.10
interleukin 2 receptor subunit beta
chr17_-_43546323 0.72 ENST00000545954.5
ENST00000319349.10
ETS variant transcription factor 4
chr4_-_88231322 0.72 ENST00000515655.5
ATP binding cassette subfamily G member 2 (Junior blood group)
chr1_-_12618198 0.71 ENST00000616661.5
dehydrogenase/reductase 3
chr11_+_7576975 0.71 ENST00000684215.1
ENST00000650027.1
PPFIA binding protein 2
chr9_-_14722725 0.71 ENST00000380911.4
cerberus 1, DAN family BMP antagonist
chr2_+_11133119 0.70 ENST00000381585.8
ENST00000405022.3
chromosome 2 open reading frame 50
chr1_+_15153698 0.70 ENST00000400796.7
ENST00000376008.3
ENST00000434578.6
transmembrane protein 51
chr20_-_45115149 0.70 ENST00000307971.7
ENST00000372789.5
WAP four-disulfide core domain 5
chr12_-_6635938 0.70 ENST00000329858.9
lysophosphatidic acid receptor 5
chr4_+_139665768 0.70 ENST00000616265.4
ENST00000265498.6
ENST00000506797.5
microsomal glutathione S-transferase 2
chr1_+_32753991 0.70 ENST00000373481.7
KIAA1522
chr18_-_55422492 0.69 ENST00000561992.5
ENST00000630712.2
transcription factor 4
chr3_-_69386079 0.69 ENST00000398540.8
FERM domain containing 4B
chr19_-_51723968 0.67 ENST00000222115.5
ENST00000540069.7
hyaluronan synthase 1
chr18_-_55587335 0.66 ENST00000638154.3
transcription factor 4
chr15_-_78944985 0.66 ENST00000615999.5
ENST00000677789.1
ENST00000676880.1
ENST00000677936.1
ENST00000220166.10
ENST00000677810.1
ENST00000678644.1
ENST00000677534.1
ENST00000677316.1
cathepsin H
chr4_-_145938473 0.65 ENST00000513320.5
zinc finger protein 827
chr1_-_44031352 0.65 ENST00000372306.7
ENST00000475075.6
solute carrier family 6 member 9
chr17_-_41620801 0.65 ENST00000648859.1
keratin 17
chr11_+_102317492 0.64 ENST00000673846.1
baculoviral IAP repeat containing 3
chr14_+_22226711 0.64 ENST00000390463.3
T cell receptor alpha variable 36/delta variable 7
chr12_-_26125023 0.63 ENST00000242728.5
basic helix-loop-helix family member e41
chrX_-_120311408 0.63 ENST00000309720.9
transmembrane protein 255A
chr1_-_28176665 0.63 ENST00000373857.8
platelet activating factor receptor
chr11_+_10455292 0.63 ENST00000396553.6
adenosine monophosphate deaminase 3
chr7_-_44325490 0.62 ENST00000350811.7
calcium/calmodulin dependent protein kinase II beta
chr1_+_26543106 0.62 ENST00000530003.5
ribosomal protein S6 kinase A1
chr6_-_6007511 0.62 ENST00000616243.1
neuritin 1
chr1_-_44031446 0.61 ENST00000372310.8
ENST00000466926.1
solute carrier family 6 member 9
chr4_+_76435216 0.61 ENST00000296043.7
shroom family member 3
chr5_+_66596346 0.60 ENST00000403625.6
ENST00000406374.5
microtubule associated serine/threonine kinase family member 4
chr4_+_1793285 0.60 ENST00000440486.8
ENST00000412135.7
ENST00000481110.7
ENST00000340107.8
fibroblast growth factor receptor 3
chr1_+_92029971 0.59 ENST00000370383.5
epoxide hydrolase 4
chr14_-_99272184 0.59 ENST00000357195.8
BAF chromatin remodeling complex subunit BCL11B
chr3_-_47443092 0.59 ENST00000545718.2
ENST00000495603.2
SREBF chaperone
chr19_+_45340774 0.59 ENST00000589837.5
kinesin light chain 3
chr12_-_84911178 0.59 ENST00000681688.1
solute carrier family 6 member 15
chr7_-_44325421 0.58 ENST00000395747.6
ENST00000347193.8
ENST00000346990.8
ENST00000258682.10
ENST00000353625.8
ENST00000421607.1
ENST00000424197.5
calcium/calmodulin dependent protein kinase II beta
chr14_+_67619911 0.58 ENST00000261783.4
arginase 2
chr9_+_98807619 0.57 ENST00000375011.4
polypeptide N-acetylgalactosaminyltransferase 12
chr13_+_79481446 0.57 ENST00000487865.5
Nedd4 family interacting protein 2
chr16_-_11273610 0.57 ENST00000327157.4
protamine 3
chr14_+_61529005 0.56 ENST00000556347.1
novel protein
chr17_+_8039106 0.56 ENST00000573359.1
arachidonate 15-lipoxygenase type B
chr1_+_233614096 0.56 ENST00000366621.8
potassium two pore domain channel subfamily K member 1
chr11_-_72781833 0.55 ENST00000535054.1
ENST00000545082.5
StAR related lipid transfer domain containing 10
chr12_-_84912705 0.55 ENST00000679933.1
ENST00000680260.1
ENST00000551010.2
ENST00000679453.1
ENST00000681281.1
solute carrier family 6 member 15
chr3_-_169663704 0.55 ENST00000651503.2
ENST00000494292.6
ENST00000486748.2
MDS1 and EVI1 complex locus
chr1_+_13584262 0.55 ENST00000376061.8
ENST00000513143.5
podoplanin
chr12_+_122021850 0.55 ENST00000261822.5
BAF chromatin remodeling complex subunit BCL7A
chr12_+_56079843 0.55 ENST00000549282.5
ENST00000549061.5
ENST00000683059.1
erb-b2 receptor tyrosine kinase 3
chr9_+_128882502 0.55 ENST00000259324.5
leucine rich repeat containing 8 VRAC subunit A
chr1_+_13583762 0.55 ENST00000376057.8
ENST00000621990.5
ENST00000510906.5
podoplanin
chr12_-_23951020 0.55 ENST00000441133.2
ENST00000545921.5
SRY-box transcription factor 5
chr17_-_7114240 0.54 ENST00000446679.6
asialoglycoprotein receptor 2
chr4_+_8229170 0.54 ENST00000511002.6
SH3 domain and tetratricopeptide repeats 1
chrX_-_153886132 0.53 ENST00000370055.5
ENST00000370060.7
ENST00000420165.5
L1 cell adhesion molecule
chr10_+_86654541 0.53 ENST00000241891.10
ENST00000372071.6
opsin 4
chr4_-_145938775 0.53 ENST00000508784.6
zinc finger protein 827
chr3_-_169147734 0.53 ENST00000464456.5
MDS1 and EVI1 complex locus
chr3_-_46693664 0.52 ENST00000318962.9
ALS2 C-terminal like
chr1_+_160796098 0.52 ENST00000392203.8
lymphocyte antigen 9
chr3_-_13880059 0.52 ENST00000285018.5
Wnt family member 7A
chr19_-_11577632 0.52 ENST00000590420.1
ENST00000648477.1
acid phosphatase 5, tartrate resistant
chr1_+_158254414 0.52 ENST00000289429.6
CD1a molecule
chr16_-_23510389 0.52 ENST00000562117.1
ENST00000567468.5
ENST00000562944.5
ENST00000309859.8
golgi associated, gamma adaptin ear containing, ARF binding protein 2
chr12_+_56080155 0.51 ENST00000267101.8
erb-b2 receptor tyrosine kinase 3
chr1_+_24319342 0.51 ENST00000361548.9
grainyhead like transcription factor 3
chr1_+_24319511 0.51 ENST00000356046.6
grainyhead like transcription factor 3
chrX_-_32155462 0.51 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chr1_+_160796070 0.49 ENST00000368037.9
lymphocyte antigen 9
chr12_+_10010627 0.49 ENST00000338896.11
ENST00000396502.5
C-type lectin domain family 12 member B
chr15_+_47717344 0.48 ENST00000558816.5
ENST00000536845.7
semaphorin 6D
chr10_+_23694707 0.48 ENST00000376462.5
KIAA1217
chr4_-_142846275 0.48 ENST00000513000.5
ENST00000509777.5
ENST00000503927.5
inositol polyphosphate-4-phosphatase type II B
chr6_-_11807045 0.48 ENST00000379415.6
androgen dependent TFPI regulating protein
chr2_-_74553049 0.47 ENST00000409549.5
lysyl oxidase like 3
chr2_-_96035974 0.47 ENST00000434632.5
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr20_+_44715360 0.47 ENST00000190983.5
cellular communication network factor 5
chr2_+_74654228 0.47 ENST00000611975.4
ENST00000357877.7
ENST00000339773.9
ENST00000434486.5
ssemaphorin 4F
chr10_+_24208774 0.47 ENST00000376456.8
ENST00000458595.5
ENST00000376452.7
ENST00000430453.6
KIAA1217
chr5_+_148268741 0.47 ENST00000398450.5
serine peptidase inhibitor Kazal type 13
chr9_-_122228845 0.46 ENST00000394319.8
ENST00000340587.7
LIM homeobox 6
chr21_+_44697172 0.46 ENST00000400365.3
keratin associated protein 10-12
chr8_-_88327475 0.46 ENST00000286614.11
matrix metallopeptidase 16
chr8_-_10730498 0.46 ENST00000304501.2
SRY-box transcription factor 7
chr9_+_128882119 0.46 ENST00000372600.9
ENST00000372599.7
leucine rich repeat containing 8 VRAC subunit A

Network of associatons between targets according to the STRING database.

First level regulatory network of EPAS1_BCL3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.8 5.1 GO:0006196 AMP catabolic process(GO:0006196)
0.8 3.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.6 8.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.6 9.1 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.5 1.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.5 1.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.4 1.3 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.4 3.5 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.4 1.2 GO:0060279 positive regulation of ovulation(GO:0060279)
0.4 1.1 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.3 1.7 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 1.0 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.3 1.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.3 0.9 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.3 1.5 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) positive regulation of leukocyte tethering or rolling(GO:1903238)
0.3 3.6 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.3 0.9 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.3 1.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.3 4.9 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.3 1.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.3 3.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.3 1.0 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.2 0.7 GO:0048391 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 1.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 0.7 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.2 1.0 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 0.9 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.2 1.4 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.2 0.9 GO:1990523 bone regeneration(GO:1990523)
0.2 0.4 GO:0072190 ureter urothelium development(GO:0072190)
0.2 1.1 GO:0071109 superior temporal gyrus development(GO:0071109)
0.2 2.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.2 0.8 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.2 1.4 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.2 2.4 GO:1902414 protein localization to cell junction(GO:1902414)
0.2 0.7 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 1.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 0.7 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.2 0.5 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.2 0.5 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.2 3.3 GO:0015732 prostaglandin transport(GO:0015732)
0.2 0.6 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 0.5 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 0.5 GO:0003409 optic cup structural organization(GO:0003409)
0.1 0.3 GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1 2.0 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1 1.0 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 2.5 GO:0097264 self proteolysis(GO:0097264)
0.1 1.7 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 1.1 GO:0097491 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1 0.3 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.1 0.3 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.1 2.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.3 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.8 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.3 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.1 0.6 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 1.0 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.1 0.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.4 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 1.6 GO:0035878 nail development(GO:0035878)
0.1 0.2 GO:0050705 regulation of interleukin-1 alpha secretion(GO:0050705)
0.1 2.3 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.4 GO:1904327 tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.5 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.4 GO:0006710 androgen catabolic process(GO:0006710)
0.1 0.3 GO:0090134 corticotropin hormone secreting cell differentiation(GO:0060128) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.6 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 1.9 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.4 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 1.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.5 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.3 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
0.1 0.2 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.3 GO:0051714 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.3 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.3 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 1.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.4 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 1.1 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.7 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.2 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.3 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.3 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 1.2 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 0.2 GO:2000282 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.3 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.3 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.4 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.8 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 0.1 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.1 0.4 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.6 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.2 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 6.9 GO:0006970 response to osmotic stress(GO:0006970)
0.1 0.7 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.8 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.8 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 0.5 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.4 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.5 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 6.7 GO:0070268 cornification(GO:0070268)
0.1 3.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.6 GO:0015886 heme transport(GO:0015886)
0.1 0.5 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.4 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.8 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.5 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.0 0.2 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.2 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.9 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.1 GO:0097168 transforming growth factor beta activation(GO:0036363) mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.1 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.3 GO:2000489 regulation of hepatic stellate cell activation(GO:2000489) negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.3 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 1.1 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 1.0 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.2 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 1.3 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 1.3 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.6 GO:0000050 urea cycle(GO:0000050)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.6 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.3 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 1.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 1.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.0 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0051695 actin filament uncapping(GO:0051695)
0.0 0.3 GO:0086068 Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790) medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.1 GO:0060621 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.0 GO:0060166 olfactory pit development(GO:0060166)
0.0 1.9 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 0.3 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 1.0 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.5 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.5 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.8 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.5 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.8 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.1 GO:2000275 cellular amide catabolic process(GO:0043605) regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0 0.7 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 2.5 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 1.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.1 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.2 GO:1902739 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.4 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.0 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.0 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 0.1 GO:0019376 galactolipid catabolic process(GO:0019376)
0.0 0.0 GO:2000416 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) negative regulation of eosinophil activation(GO:1902567) negative regulation of membrane invagination(GO:1905154) regulation of eosinophil migration(GO:2000416) negative regulation of eosinophil migration(GO:2000417)
0.0 0.5 GO:0021591 ventricular system development(GO:0021591)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.5 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0015695 organic cation transport(GO:0015695)
0.0 0.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233) positive regulation of TORC1 signaling(GO:1904263) cellular response to leucine starvation(GO:1990253)
0.0 0.0 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.0 4.3 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.2 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:1903300 response to fructose(GO:0009750) negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.6 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.0 GO:0060084 positive regulation of dopamine secretion(GO:0033603) synaptic transmission involved in micturition(GO:0060084)
0.0 0.2 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.6 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.0 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.0 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.0 0.1 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.1 GO:0097647 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 1.1 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.0 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.3 GO:0060384 innervation(GO:0060384)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 9.8 GO:0072534 perineuronal net(GO:0072534)
1.0 8.4 GO:0097451 glial limiting end-foot(GO:0097451)
0.3 0.8 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 1.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.2 2.6 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 2.2 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 6.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 1.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 1.7 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.9 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 1.1 GO:0033010 paranodal junction(GO:0033010)
0.1 4.3 GO:0001772 immunological synapse(GO:0001772)
0.1 3.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.2 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.3 GO:0032280 symmetric synapse(GO:0032280)
0.0 2.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 3.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.5 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.7 GO:0001533 cornified envelope(GO:0001533)
0.0 1.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 4.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 3.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 4.2 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 4.0 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 1.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0005845 mRNA cap binding complex(GO:0005845) RISC-loading complex(GO:0070578)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 2.8 GO:0043296 apical junction complex(GO:0043296)
0.0 0.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 1.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 1.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.0 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.6 5.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 1.5 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.5 3.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.4 1.5 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.4 1.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.3 2.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.3 1.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 0.9 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.3 9.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 1.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.2 0.9 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 0.9 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.2 2.7 GO:0038132 neuregulin binding(GO:0038132)
0.2 1.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 1.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.6 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.2 0.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 3.8 GO:0048185 activin binding(GO:0048185)
0.2 0.7 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.2 0.7 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 0.7 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.2 1.1 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.3 GO:0098639 collagen receptor activity(GO:0038064) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 4.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 0.5 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 2.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 2.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.3 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.4 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 1.0 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.4 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.6 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 8.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 2.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.5 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.5 GO:0042835 BRE binding(GO:0042835)
0.1 1.1 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0001626 nociceptin receptor activity(GO:0001626)
0.1 0.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 3.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 1.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.4 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 0.7 GO:0016015 morphogen activity(GO:0016015)
0.1 0.2 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 1.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.6 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.6 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 5.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 1.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 1.3 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 1.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.7 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 4.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 1.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 3.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0035731 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
0.0 0.1 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.0 0.9 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.0 GO:0070697 activin receptor binding(GO:0070697)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.5 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 3.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 1.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 2.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.4 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.5 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.1 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.1 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.3 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 1.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.3 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 6.0 PID BMP PATHWAY BMP receptor signaling
0.1 4.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 3.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 1.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID SHP2 PATHWAY SHP2 signaling
0.0 1.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.0 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.9 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.8 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID EPO PATHWAY EPO signaling pathway
0.0 2.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 ST GAQ PATHWAY G alpha q Pathway
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.8 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 4.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 3.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 5.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.1 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 0.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 2.4 REACTOME KINESINS Genes involved in Kinesins
0.1 0.5 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 1.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.6 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 2.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 0.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 2.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 3.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 0.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 1.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.6 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 2.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane