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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ETV6

Z-value: 0.58

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Transcription factors associated with ETV6

Gene Symbol Gene ID Gene Info
ETV6
ENSG00000139083.11 ETS variant transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ETV6hg38_v1_chr12_+_11649666_11649751-0.686.3e-02Click!

Activity profile of ETV6 motif

Sorted Z-values of ETV6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_225042433 0.42 ENST00000258390.12
DOCK10
dedicator of cytokinesis 10
chr16_+_75222609 0.35 ENST00000495583.1
CTRB1
chymotrypsinogen B1
chr11_+_124954108 0.30 ENST00000529051.5
CCDC15
coiled-coil domain containing 15
chr11_+_124954175 0.26 ENST00000344762.6
CCDC15
coiled-coil domain containing 15
chr21_-_44920918 0.22 ENST00000522688.5
ITGB2
integrin subunit beta 2
chr1_-_149927756 0.22 ENST00000271628.9
SF3B4
splicing factor 3b subunit 4
chr17_+_82228397 0.20 ENST00000584689.6
ENST00000392341.6
SLC16A3
solute carrier family 16 member 3
chr9_-_112175185 0.20 ENST00000355396.7
SUSD1
sushi domain containing 1
chr2_+_202033847 0.19 ENST00000286201.3
FZD7
frizzled class receptor 7
chr5_+_95731300 0.19 ENST00000379982.8
RHOBTB3
Rho related BTB domain containing 3
chrX_+_70290077 0.17 ENST00000374403.4
KIF4A
kinesin family member 4A
chr2_+_65227792 0.17 ENST00000260641.10
ENST00000377982.8
ACTR2
actin related protein 2
chr2_+_188291854 0.16 ENST00000409830.6
GULP1
GULP PTB domain containing engulfment adaptor 1
chr3_-_16513643 0.15 ENST00000334133.9
RFTN1
raftlin, lipid raft linker 1
chr6_+_3068487 0.15 ENST00000259808.9
RIPK1
receptor interacting serine/threonine kinase 1
chr10_-_97401277 0.15 ENST00000315563.10
ENST00000370992.9
ENST00000414986.5
RRP12
ribosomal RNA processing 12 homolog
chr2_+_188291661 0.15 ENST00000409843.5
GULP1
GULP PTB domain containing engulfment adaptor 1
chr8_-_47960126 0.15 ENST00000314191.7
ENST00000338368.7
PRKDC
protein kinase, DNA-activated, catalytic subunit
chr9_-_14693419 0.14 ENST00000380916.9
ZDHHC21
zinc finger DHHC-type palmitoyltransferase 21
chr2_+_188291994 0.14 ENST00000409927.5
ENST00000409805.5
GULP1
GULP PTB domain containing engulfment adaptor 1
chr10_+_26697653 0.13 ENST00000376215.10
PDSS1
decaprenyl diphosphate synthase subunit 1
chr16_+_30395400 0.13 ENST00000320159.2
ENST00000613509.2
ZNF48
zinc finger protein 48
chr16_-_3305397 0.13 ENST00000396862.2
TIGD7
tigger transposable element derived 7
chr19_+_1249870 0.13 ENST00000591446.6
MIDN
midnolin
chr6_+_30557274 0.13 ENST00000376557.3
PRR3
proline rich 3
chr19_+_48872412 0.13 ENST00000200453.6
PPP1R15A
protein phosphatase 1 regulatory subunit 15A
chr5_+_321695 0.13 ENST00000684583.1
ENST00000514523.1
AHRR
aryl-hydrocarbon receptor repressor
chr2_-_96305521 0.13 ENST00000323853.10
SNRNP200
small nuclear ribonucleoprotein U5 subunit 200
chr17_-_81918134 0.13 ENST00000328666.11
SIRT7
sirtuin 7
chr15_-_50765656 0.13 ENST00000261854.10
SPPL2A
signal peptide peptidase like 2A
chr19_-_15233432 0.13 ENST00000602233.5
EPHX3
epoxide hydrolase 3
chr6_+_30557287 0.13 ENST00000376560.8
PRR3
proline rich 3
chr17_-_40417873 0.13 ENST00000423485.6
TOP2A
DNA topoisomerase II alpha
chr6_-_11382247 0.13 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr15_+_90717321 0.12 ENST00000355112.8
ENST00000681142.1
ENST00000648453.1
ENST00000560509.5
BLM
BLM RecQ like helicase
chr9_-_112175283 0.12 ENST00000374270.8
ENST00000374263.7
SUSD1
sushi domain containing 1
chr5_+_103120264 0.12 ENST00000358359.8
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr17_+_50373214 0.12 ENST00000393271.6
ENST00000338165.9
ENST00000511519.6
EME1
essential meiotic structure-specific endonuclease 1
chr20_+_5950630 0.12 ENST00000378883.5
ENST00000378896.7
ENST00000378886.6
ENST00000610722.4
MCM8
minichromosome maintenance 8 homologous recombination repair factor
chr16_+_3305472 0.12 ENST00000574298.6
ENST00000669516.2
ZNF75A
zinc finger protein 75a
chr5_-_36151853 0.12 ENST00000296603.5
LMBRD2
LMBR1 domain containing 2
chr7_+_155298561 0.12 ENST00000476756.1
INSIG1
insulin induced gene 1
chr3_-_123961200 0.12 ENST00000409697.8
ENST00000310351.8
CCDC14
coiled-coil domain containing 14
chr21_-_28992947 0.11 ENST00000389194.7
ENST00000389195.7
ENST00000614971.4
LTN1
listerin E3 ubiquitin protein ligase 1
chr3_-_123961399 0.11 ENST00000488653.6
CCDC14
coiled-coil domain containing 14
chr5_-_40798371 0.11 ENST00000354209.7
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
chr17_+_28662183 0.11 ENST00000347486.8
ENST00000314616.11
SUPT6H
SPT6 homolog, histone chaperone and transcription elongation factor
chr13_+_112969179 0.11 ENST00000535094.7
MCF2L
MCF.2 cell line derived transforming sequence like
chr5_+_73813518 0.11 ENST00000296799.8
ARHGEF28
Rho guanine nucleotide exchange factor 28
chr4_+_147617366 0.11 ENST00000508208.5
ENST00000296582.8
TMEM184C
transmembrane protein 184C
chr2_+_128091166 0.11 ENST00000259253.11
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr4_-_163473732 0.11 ENST00000280605.5
TKTL2
transketolase like 2
chr5_+_102865805 0.11 ENST00000346918.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr5_+_103120149 0.11 ENST00000515845.5
ENST00000321521.13
ENST00000507921.5
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr15_-_43266857 0.11 ENST00000349114.8
ENST00000220420.10
TGM5
transglutaminase 5
chr11_-_65084024 0.11 ENST00000275517.8
ENST00000404147.3
CDCA5
cell division cycle associated 5
chr5_-_37371061 0.10 ENST00000513532.1
ENST00000231498.8
NUP155
nucleoporin 155
chr3_-_128052166 0.10 ENST00000648300.1
MGLL
monoglyceride lipase
chr14_-_21383989 0.10 ENST00000216297.7
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit
chr12_+_131929194 0.10 ENST00000443358.6
PUS1
pseudouridine synthase 1
chr5_-_151093566 0.10 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr10_-_78029487 0.10 ENST00000372371.8
POLR3A
RNA polymerase III subunit A
chr4_+_6575168 0.10 ENST00000504248.5
ENST00000285599.8
ENST00000505907.1
MAN2B2
mannosidase alpha class 2B member 2
chr21_-_28992815 0.10 ENST00000361371.10
LTN1
listerin E3 ubiquitin protein ligase 1
chr11_-_8168987 0.10 ENST00000425599.6
ENST00000531450.1
ENST00000309737.11
ENST00000419822.2
ENST00000335425.7
ENST00000343202.8
RIC3
RIC3 acetylcholine receptor chaperone
chr20_-_5950463 0.10 ENST00000203001.7
ENST00000453074.6
TRMT6
tRNA methyltransferase 6
chr11_-_123741614 0.10 ENST00000526252.5
ENST00000530393.6
ENST00000533463.5
ENST00000336139.8
ENST00000529691.1
ENST00000528306.5
ZNF202
zinc finger protein 202
chr2_+_218672027 0.10 ENST00000392105.7
ENST00000455724.5
ENST00000295709.8
STK36
serine/threonine kinase 36
chr12_+_131929259 0.09 ENST00000542167.2
ENST00000376649.8
ENST00000538037.5
ENST00000456665.6
PUS1
pseudouridine synthase 1
chr17_+_7932101 0.09 ENST00000576538.5
ENST00000380262.7
ENST00000563694.6
ENST00000570782.1
CNTROB
centrobin, centriole duplication and spindle assembly protein
chr9_-_69759994 0.09 ENST00000340434.5
PTAR1
protein prenyltransferase alpha subunit repeat containing 1
chr12_+_123712333 0.09 ENST00000330342.8
ENST00000613625.5
ATP6V0A2
ATPase H+ transporting V0 subunit a2
chr17_-_78840881 0.09 ENST00000312010.10
USP36
ubiquitin specific peptidase 36
chr15_+_90388234 0.09 ENST00000268182.10
ENST00000560738.1
ENST00000560418.1
IQGAP1
IQ motif containing GTPase activating protein 1
chr17_+_7583828 0.09 ENST00000396501.8
ENST00000250124.11
ENST00000584378.5
ENST00000423172.6
ENST00000579445.5
ENST00000585217.5
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr9_-_83956677 0.09 ENST00000376344.8
C9orf64
chromosome 9 open reading frame 64
chr2_-_75710985 0.09 ENST00000541687.5
GCFC2
GC-rich sequence DNA-binding factor 2
chr12_-_55829580 0.09 ENST00000678005.2
ENST00000546957.2
DNAJC14
DnaJ heat shock protein family (Hsp40) member C14
chr1_+_111755892 0.09 ENST00000369702.5
ENST00000680627.1
ENST00000680518.1
DDX20
DEAD-box helicase 20
chr13_-_28718921 0.09 ENST00000266943.11
ENST00000380814.4
SLC46A3
solute carrier family 46 member 3
chr1_+_236795254 0.09 ENST00000366577.10
ENST00000674797.2
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase
chrX_+_11111291 0.09 ENST00000321143.8
ENST00000380762.5
ENST00000380763.7
HCCS
holocytochrome c synthase
chrX_+_46447279 0.09 ENST00000298190.10
ENST00000377919.6
ENST00000476762.5
ENST00000344302.9
ENST00000478600.5
KRBOX4
KRAB box domain containing 4
chr20_+_41340878 0.09 ENST00000632009.1
LPIN3
lipin 3
chr11_+_123358416 0.09 ENST00000638157.1
GRAMD1B
GRAM domain containing 1B
chr2_-_223838022 0.09 ENST00000444408.1
AP1S3
adaptor related protein complex 1 subunit sigma 3
chr14_+_103100328 0.09 ENST00000559116.1
EXOC3L4
exocyst complex component 3 like 4
chr20_+_41340780 0.09 ENST00000373257.8
LPIN3
lipin 3
chr9_-_33264559 0.09 ENST00000473781.1
ENST00000379704.7
ENST00000488499.1
BAG1
BAG cochaperone 1
chr9_+_4662281 0.08 ENST00000381883.5
PLPP6
phospholipid phosphatase 6
chr2_-_218671975 0.08 ENST00000295704.7
RNF25
ring finger protein 25
chr1_-_120100688 0.08 ENST00000652264.1
NOTCH2
notch receptor 2
chr17_-_42577663 0.08 ENST00000590760.5
ENST00000587209.5
ENST00000393795.8
ENST00000253789.9
PSMC3IP
PSMC3 interacting protein
chr7_+_151232464 0.08 ENST00000482173.5
ENST00000495645.5
ENST00000035307.6
CHPF2
chondroitin polymerizing factor 2
chr15_-_101277287 0.08 ENST00000528346.1
ENST00000531964.5
ENST00000398226.7
ENST00000526049.6
SELENOS
selenoprotein S
chr16_+_67192116 0.08 ENST00000379378.8
E2F4
E2F transcription factor 4
chr2_-_197310646 0.08 ENST00000647377.1
ANKRD44
ankyrin repeat domain 44
chrX_+_27807990 0.08 ENST00000356790.2
MAGEB10
MAGE family member B10
chr6_+_31666056 0.08 ENST00000375882.7
ENST00000375880.6
CSNK2B
ENSG00000263020.6
casein kinase 2 beta
novel protein
chr17_+_81683963 0.08 ENST00000676462.1
ENST00000679336.1
ENST00000678196.1
ENST00000677243.1
ENST00000677044.1
ENST00000677109.1
ENST00000677484.1
ENST00000678105.1
ENST00000677209.1
ENST00000329138.9
ENST00000677225.1
ENST00000678866.1
ENST00000676729.1
ENST00000572392.2
ENST00000577012.1
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr7_+_100884974 0.08 ENST00000448764.5
SRRT
serrate, RNA effector molecule
chr19_+_13906255 0.08 ENST00000589606.5
CC2D1A
coiled-coil and C2 domain containing 1A
chr1_+_230747381 0.08 ENST00000366666.6
ENST00000271971.7
ENST00000354537.1
CAPN9
calpain 9
chr1_+_2586750 0.08 ENST00000444521.6
ENST00000378425.9
ENST00000419916.8
ENST00000378424.9
ENST00000537325.6
ENST00000378427.6
ENST00000465233.6
ENST00000498083.2
PRXL2B
peroxiredoxin like 2B
chr11_+_61792878 0.08 ENST00000305885.3
ENST00000535723.1
FEN1
flap structure-specific endonuclease 1
chr19_-_16660104 0.08 ENST00000593459.5
ENST00000627144.2
ENST00000358726.6
ENST00000487416.7
ENST00000597711.5
ENSG00000268790.5
SMIM7
novel protein
small integral membrane protein 7
chr16_-_18926408 0.08 ENST00000446231.7
SMG1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr2_+_65228122 0.08 ENST00000542850.2
ACTR2
actin related protein 2
chr19_+_45039040 0.08 ENST00000221455.8
ENST00000391953.8
ENST00000588936.5
CLASRP
CLK4 associating serine/arginine rich protein
chr9_-_129824098 0.08 ENST00000351698.5
TOR1A
torsin family 1 member A
chr2_+_218672291 0.08 ENST00000440309.5
ENST00000424080.1
STK36
serine/threonine kinase 36
chr6_-_43528867 0.08 ENST00000455285.2
XPO5
exportin 5
chr9_-_129824236 0.08 ENST00000651202.1
TOR1A
torsin family 1 member A
chr19_-_36772791 0.07 ENST00000591344.2
ENST00000614887.4
ZNF850
zinc finger protein 850
chr11_-_62621977 0.07 ENST00000534026.5
ENST00000265471.10
B3GAT3
beta-1,3-glucuronyltransferase 3
chr6_-_77463485 0.07 ENST00000369947.5
HTR1B
5-hydroxytryptamine receptor 1B
chr5_+_168486462 0.07 ENST00000231572.8
ENST00000626454.1
RARS1
arginyl-tRNA synthetase 1
chr16_+_69339758 0.07 ENST00000254940.10
ENST00000254941.6
NIP7
nucleolar pre-rRNA processing protein NIP7
chr13_-_99258366 0.07 ENST00000397470.5
ENST00000397473.7
GPR18
G protein-coupled receptor 18
chr2_+_3379668 0.07 ENST00000382110.6
ENST00000324266.10
TRAPPC12
trafficking protein particle complex 12
chr12_+_131929219 0.07 ENST00000322060.9
PUS1
pseudouridine synthase 1
chr9_-_122931477 0.07 ENST00000373656.4
ZBTB26
zinc finger and BTB domain containing 26
chr1_-_223845894 0.07 ENST00000391878.6
ENST00000343537.12
TP53BP2
tumor protein p53 binding protein 2
chr13_-_31161890 0.07 ENST00000320027.10
HSPH1
heat shock protein family H (Hsp110) member 1
chr3_+_128052390 0.07 ENST00000481210.5
ENST00000243253.8
SEC61A1
SEC61 translocon subunit alpha 1
chr7_+_32495447 0.07 ENST00000318709.9
ENST00000409301.5
ENST00000640103.1
AVL9
AVL9 cell migration associated
chr15_-_65517244 0.07 ENST00000341861.9
DPP8
dipeptidyl peptidase 8
chr2_+_36355712 0.07 ENST00000280527.7
CRIM1
cysteine rich transmembrane BMP regulator 1
chr19_+_13906190 0.07 ENST00000318003.11
CC2D1A
coiled-coil and C2 domain containing 1A
chr19_-_9498596 0.07 ENST00000301480.5
ZNF560
zinc finger protein 560
chr3_+_42936859 0.07 ENST00000446977.2
ENST00000418176.1
ENSG00000273291.5
KRBOX1
novel protein
KRAB box domain containing 1
chr2_-_121736911 0.07 ENST00000451734.1
NIFK
nucleolar protein interacting with the FHA domain of MKI67
chr17_+_19127535 0.07 ENST00000577213.1
ENST00000344415.9
GRAPL
GRB2 related adaptor protein like
chr2_-_174682854 0.07 ENST00000409415.7
ENST00000359761.7
ENST00000272746.9
WIPF1
WAS/WASL interacting protein family member 1
chr20_-_35284745 0.07 ENST00000374443.7
ENST00000374450.8
EIF6
eukaryotic translation initiation factor 6
chr19_-_56314788 0.07 ENST00000592509.5
ENST00000592679.5
ENST00000683990.1
ENST00000588442.5
ENST00000593106.5
ENST00000587492.5
ZSCAN5A
zinc finger and SCAN domain containing 5A
chr17_+_63827406 0.07 ENST00000310144.11
ENST00000581842.5
ENST00000582130.5
ENST00000584320.5
ENST00000585123.5
ENST00000580864.5
PSMC5
proteasome 26S subunit, ATPase 5
chr9_-_69759932 0.07 ENST00000377200.9
ENST00000472967.2
PTAR1
protein prenyltransferase alpha subunit repeat containing 1
chr5_+_179698367 0.07 ENST00000680406.1
ENST00000502296.6
ENST00000504734.5
CANX
calnexin
chr1_+_154220179 0.07 ENST00000343815.10
UBAP2L
ubiquitin associated protein 2 like
chr1_-_150234668 0.07 ENST00000616917.4
ANP32E
acidic nuclear phosphoprotein 32 family member E
chr13_-_31162341 0.07 ENST00000445273.6
ENST00000630972.2
HSPH1
heat shock protein family H (Hsp110) member 1
chr12_+_119667859 0.07 ENST00000541640.5
PRKAB1
protein kinase AMP-activated non-catalytic subunit beta 1
chr12_-_6606320 0.07 ENST00000642594.1
ENST00000644289.1
ENST00000645095.1
CHD4
chromodomain helicase DNA binding protein 4
chr11_+_60914139 0.07 ENST00000227525.8
TMEM109
transmembrane protein 109
chr17_-_78840647 0.07 ENST00000587783.5
ENST00000542802.7
ENST00000586531.5
ENST00000589424.5
ENST00000590546.6
USP36
ubiquitin specific peptidase 36
chr11_+_57667747 0.07 ENST00000527985.5
ZDHHC5
zinc finger DHHC-type palmitoyltransferase 5
chr9_+_128504655 0.07 ENST00000683748.1
ENST00000684314.1
ENST00000684331.1
ENST00000684646.1
ENST00000309971.9
ENST00000684139.1
ENST00000372770.4
GLE1
GLE1 RNA export mediator
chr10_+_42782769 0.07 ENST00000374518.6
BMS1
BMS1 ribosome biogenesis factor
chr1_-_246566238 0.07 ENST00000366514.5
TFB2M
transcription factor B2, mitochondrial
chr20_+_2840694 0.07 ENST00000380469.7
ENST00000380445.8
ENST00000453689.5
ENST00000417508.1
VPS16
VPS16 core subunit of CORVET and HOPS complexes
chr12_+_56118241 0.07 ENST00000551790.5
ENST00000552345.1
ENST00000257940.7
ENST00000551880.1
ESYT1
ZC3H10
extended synaptotagmin 1
zinc finger CCCH-type containing 10
chr17_-_39688016 0.07 ENST00000579146.5
ENST00000300658.9
ENST00000378011.8
ENST00000429199.6
PGAP3
post-GPI attachment to proteins phospholipase 3
chr1_-_165768835 0.07 ENST00000481278.5
TMCO1
transmembrane and coiled-coil domains 1
chr19_-_9435490 0.07 ENST00000592292.5
ENST00000588221.5
ZNF266
zinc finger protein 266
chr1_-_113759099 0.07 ENST00000393357.6
ENST00000446739.1
PHTF1
putative homeodomain transcription factor 1
chr8_+_120445402 0.07 ENST00000305949.6
MTBP
MDM2 binding protein
chr9_-_112175264 0.07 ENST00000374264.6
SUSD1
sushi domain containing 1
chr20_-_35284715 0.06 ENST00000374436.7
ENST00000675032.1
EIF6
eukaryotic translation initiation factor 6
chr9_+_37753798 0.06 ENST00000377753.6
ENST00000537911.5
ENST00000297994.4
ENST00000377754.6
TRMT10B
tRNA methyltransferase 10B
chr16_-_27549887 0.06 ENST00000561623.5
ENST00000356183.9
GTF3C1
general transcription factor IIIC subunit 1
chr12_-_8949628 0.06 ENST00000000412.8
ENST00000543845.1
ENST00000544245.1
ENST00000536844.5
M6PR
mannose-6-phosphate receptor, cation dependent
chr2_+_63841882 0.06 ENST00000337130.10
ENST00000488245.6
UGP2
UDP-glucose pyrophosphorylase 2
chr4_+_41935114 0.06 ENST00000508448.5
ENST00000513702.5
ENST00000325094.9
TMEM33
transmembrane protein 33
chr19_-_9435551 0.06 ENST00000651268.1
ENST00000592904.7
ZNF266
zinc finger protein 266
chr3_-_138174879 0.06 ENST00000260803.9
DBR1
debranching RNA lariats 1
chr1_+_43389889 0.06 ENST00000562955.2
ENST00000634258.3
SZT2
SZT2 subunit of KICSTOR complex
chr12_-_124863783 0.06 ENST00000546215.5
ENST00000415380.6
ENST00000545493.1
ENST00000261693.11
ENST00000680596.1
SCARB1
scavenger receptor class B member 1
chr2_+_219597838 0.06 ENST00000456909.6
STK11IP
serine/threonine kinase 11 interacting protein
chr19_-_9819032 0.06 ENST00000590277.1
ENST00000588922.5
ENST00000589626.5
ENST00000247977.9
ENST00000592067.1
ENST00000586469.1
FBXL12
F-box and leucine rich repeat protein 12
chr1_+_43300971 0.06 ENST00000372476.8
ENST00000538015.1
TIE1
tyrosine kinase with immunoglobulin like and EGF like domains 1
chr12_-_124863902 0.06 ENST00000339570.9
ENST00000680556.1
SCARB1
scavenger receptor class B member 1
chr17_-_5486157 0.06 ENST00000572834.5
ENST00000158771.9
ENST00000570848.5
ENST00000571971.1
DERL2
derlin 2
chr6_-_31652358 0.06 ENST00000456622.5
ENST00000435080.5
ENST00000375976.8
ENST00000441054.5
BAG6
BAG cochaperone 6
chr9_+_70258921 0.06 ENST00000361138.7
SMC5
structural maintenance of chromosomes 5
chr22_+_40346461 0.06 ENST00000623632.4
ENST00000625194.4
ENST00000637666.2
ENST00000680978.1
ENST00000623063.3
ENST00000679723.1
ENST00000342312.9
ADSL
adenylosuccinate lyase
chr19_+_16197848 0.06 ENST00000590263.5
ENST00000590756.5
AP1M1
adaptor related protein complex 1 subunit mu 1
chr12_+_119668109 0.06 ENST00000229328.10
ENST00000630317.1
PRKAB1
protein kinase AMP-activated non-catalytic subunit beta 1
chr11_-_66002123 0.06 ENST00000532707.5
ENST00000526451.5
ENST00000312234.6
ENST00000533544.6
ENST00000530462.5
ENST00000525767.5
ENST00000529964.5
ENST00000527249.5
EIF1AD
eukaryotic translation initiation factor 1A domain containing
chr1_+_222644247 0.06 ENST00000340535.11
MIA3
MIA SH3 domain ER export factor 3
chr2_+_63842325 0.06 ENST00000445915.6
ENST00000475462.5
UGP2
UDP-glucose pyrophosphorylase 2
chr1_-_43172504 0.06 ENST00000431635.6
EBNA1BP2
EBNA1 binding protein 2
chr7_+_99616936 0.06 ENST00000394152.7
ENST00000431485.2
ZSCAN25
zinc finger and SCAN domain containing 25
chr11_-_72080389 0.06 ENST00000351960.10
ENST00000541719.5
ENST00000535111.5
NUMA1
nuclear mitotic apparatus protein 1
chr3_+_42936354 0.06 ENST00000383748.9
KRBOX1
KRAB box domain containing 1
chr1_-_20508095 0.06 ENST00000264198.5
MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr4_-_158671843 0.06 ENST00000379205.5
ENST00000508457.1
C4orf46
chromosome 4 open reading frame 46
chr12_-_6606427 0.06 ENST00000642879.1
CHD4
chromodomain helicase DNA binding protein 4
chr11_-_72080472 0.06 ENST00000537217.5
ENST00000366394.7
ENST00000358965.10
ENST00000546131.1
ENST00000393695.8
ENST00000543937.5
ENST00000368959.9
ENST00000541641.5
NUMA1
nuclear mitotic apparatus protein 1
chr14_+_74713136 0.06 ENST00000554590.5
ENST00000341162.8
ENST00000534938.6
ENST00000553615.5
FCF1
FCF1 rRNA-processing protein
chrX_+_47232866 0.06 ENST00000218348.7
ENST00000377107.7
USP11
ubiquitin specific peptidase 11
chr5_-_40798160 0.06 ENST00000296800.4
ENST00000397128.6
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
chr20_-_34677080 0.06 ENST00000374820.6
ENST00000217446.8
PIGU
phosphatidylinositol glycan anchor biosynthesis class U
chr19_-_12933680 0.06 ENST00000593021.1
ENST00000314606.9
ENST00000587981.1
ENST00000423140.6
FARSA
phenylalanyl-tRNA synthetase subunit alpha
chr2_-_121736863 0.06 ENST00000285814.9
NIFK
nucleolar protein interacting with the FHA domain of MKI67
chr11_-_47578768 0.06 ENST00000525720.1
ENST00000531067.1
ENST00000533290.5
ENST00000529499.1
ENST00000529946.1
ENST00000526005.5
ENST00000395288.6
ENST00000430070.7
ENST00000534239.1
KBTBD4
kelch repeat and BTB domain containing 4
chr11_+_61362355 0.06 ENST00000542946.1
ENST00000278826.11
TMEM138
transmembrane protein 138
chr14_-_77616630 0.06 ENST00000216484.7
SPTLC2
serine palmitoyltransferase long chain base subunit 2
chr7_+_39950013 0.06 ENST00000340829.10
CDK13
cyclin dependent kinase 13
chr5_+_68215738 0.06 ENST00000521381.6
ENST00000521657.5
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.1 0.2 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.2 GO:0009996 negative regulation of cell fate specification(GO:0009996)
0.0 0.1 GO:0032887 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.2 GO:0032242 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.0 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.2 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0035048 splicing factor protein import into nucleus(GO:0035048)
0.0 0.2 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:1904327 tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0045896 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) regulation of transcription during mitosis(GO:0045896) regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021)
0.0 0.2 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:1901563 response to camptothecin(GO:1901563)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.0 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.0 0.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.0 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.0 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.0 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.1 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.0 GO:0046967 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) cytosol to ER transport(GO:0046967)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.2 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.1 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.1 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.0 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.0 GO:0044753 amphisome(GO:0044753)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.0 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.0 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.0 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0097342 ripoptosome(GO:0097342)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.1 0.2 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416) inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.0 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.0 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.0 GO:0019211 phosphatase activator activity(GO:0019211)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters