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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for EZH2

Z-value: 0.82

Motif logo

Transcription factors associated with EZH2

Gene Symbol Gene ID Gene Info
ENSG00000106462.12 enhancer of zeste 2 polycomb repressive complex 2 subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EZH2hg38_v1_chr7_-_148883474_148883509-0.482.3e-01Click!

Activity profile of EZH2 motif

Sorted Z-values of EZH2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_41700583 1.26 ENST00000442711.1
inhibin subunit beta A
chr1_+_86424154 1.01 ENST00000370565.5
chloride channel accessory 2
chr1_-_153616289 0.85 ENST00000368701.5
ENST00000344616.4
S100 calcium binding protein A14
chr15_+_43593054 0.84 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
creatine kinase, mitochondrial 1B
chr12_-_6374803 0.80 ENST00000396966.6
sodium channel epithelial 1 subunit alpha
chr11_-_79441016 0.77 ENST00000278550.12
teneurin transmembrane protein 4
chr10_-_104085847 0.76 ENST00000648076.2
collagen type XVII alpha 1 chain
chr1_-_153615858 0.74 ENST00000476873.5
S100 calcium binding protein A14
chr15_+_43594027 0.68 ENST00000453733.5
ENST00000441322.6
ENST00000627381.1
creatine kinase, mitochondrial 1B
chr15_+_43693859 0.68 ENST00000413453.7
ENST00000415044.3
ENST00000626814.1
creatine kinase, mitochondrial 1A
chr12_-_6375209 0.66 ENST00000360168.7
sodium channel epithelial 1 subunit alpha
chr19_-_35513641 0.63 ENST00000339686.8
ENST00000447113.6
dermokine
chr7_-_22193728 0.61 ENST00000620335.4
Rap guanine nucleotide exchange factor 5
chr11_-_66729184 0.60 ENST00000533211.6
ENST00000309996.7
spectrin beta, non-erythrocytic 2
chr8_+_32647080 0.56 ENST00000520502.7
ENST00000523041.2
ENST00000650819.1
neuregulin 1
chr8_-_126558461 0.55 ENST00000304916.4
LRAT domain containing 2
chr13_-_20230970 0.55 ENST00000644667.1
ENST00000646108.1
gap junction protein beta 6
chr7_-_22193824 0.53 ENST00000401957.6
Rap guanine nucleotide exchange factor 5
chr19_-_35501878 0.51 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
dermokine
chr15_+_43692886 0.46 ENST00000434505.5
ENST00000411750.5
creatine kinase, mitochondrial 1A
chr8_-_41309434 0.46 ENST00000220772.8
secreted frizzled related protein 1
chr12_-_6375556 0.44 ENST00000228916.7
sodium channel epithelial 1 subunit alpha
chrX_-_153875847 0.43 ENST00000361699.8
ENST00000361981.7
L1 cell adhesion molecule
chr17_-_7263959 0.43 ENST00000571932.2
claudin 7
chr1_-_161021096 0.41 ENST00000537746.1
ENST00000368026.11
F11 receptor
chr7_+_121873317 0.41 ENST00000651863.1
ENST00000652298.1
ENST00000449182.1
protein tyrosine phosphatase receptor type Z1
chr3_+_189789643 0.39 ENST00000354600.10
tumor protein p63
chr7_+_121873478 0.39 ENST00000651320.1
protein tyrosine phosphatase receptor type Z1
chr6_-_136526177 0.38 ENST00000617204.4
microtubule associated protein 7
chr6_+_26500296 0.38 ENST00000684113.1
butyrophilin subfamily 1 member A1
chr10_-_114684612 0.37 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr1_-_209651291 0.37 ENST00000391911.5
ENST00000415782.1
laminin subunit beta 3
chr8_+_101492423 0.37 ENST00000521085.1
ENST00000646743.1
grainyhead like transcription factor 2
chr1_+_200894892 0.37 ENST00000413687.3
innate immunity activator
chr10_-_114684457 0.37 ENST00000392955.7
actin binding LIM protein 1
chr6_+_25279359 0.36 ENST00000329474.7
capping protein regulator and myosin 1 linker 1
chr17_-_41518878 0.35 ENST00000254043.8
keratin 15
chr6_-_136526472 0.35 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr11_-_120123026 0.35 ENST00000533302.5
tripartite motif containing 29
chr2_-_215138603 0.35 ENST00000272895.12
ATP binding cassette subfamily A member 12
chr1_+_101238090 0.34 ENST00000475289.2
sphingosine-1-phosphate receptor 1
chr19_+_35106510 0.34 ENST00000648240.1
novel protein
chr12_-_8650529 0.33 ENST00000543467.5
microfibril associated protein 5
chr17_+_57105899 0.32 ENST00000576295.5
A-kinase anchoring protein 1
chr19_-_51019699 0.32 ENST00000358789.8
kallikrein related peptidase 10
chr19_-_35510384 0.32 ENST00000602679.5
ENST00000492341.6
ENST00000472252.6
ENST00000602781.5
ENST00000402589.6
ENST00000458071.5
ENST00000436012.5
ENST00000443640.5
ENST00000450261.1
ENST00000467637.5
ENST00000480502.5
ENST00000474928.5
ENST00000414866.6
ENST00000392206.6
ENST00000488892.5
dermokine
chr19_-_51020019 0.32 ENST00000309958.7
kallikrein related peptidase 10
chr19_+_35115787 0.31 ENST00000604404.6
FXYD domain containing ion transport regulator 3
chr6_-_136526654 0.31 ENST00000611373.1
microtubule associated protein 7
chr4_+_83535914 0.31 ENST00000611707.4
glycerol-3-phosphate acyltransferase 3
chr5_+_145937793 0.30 ENST00000511217.1
SH3 domain containing ring finger 2
chr2_+_219460719 0.30 ENST00000396688.5
striated muscle enriched protein kinase
chr1_-_147773341 0.30 ENST00000430508.1
ENST00000621517.1
gap junction protein alpha 5
chr19_-_51020154 0.29 ENST00000391805.5
ENST00000599077.1
kallikrein related peptidase 10
chr6_-_47042306 0.29 ENST00000371253.7
adhesion G protein-coupled receptor F1
chr2_-_31414694 0.29 ENST00000379416.4
xanthine dehydrogenase
chr1_+_2073462 0.29 ENST00000400921.6
protein kinase C zeta
chr1_+_13585453 0.28 ENST00000487038.5
ENST00000475043.5
podoplanin
chr12_-_27972725 0.28 ENST00000545234.6
parathyroid hormone like hormone
chr12_+_56083308 0.28 ENST00000683164.1
ENST00000415288.6
ENST00000683018.1
erb-b2 receptor tyrosine kinase 3
chrX_-_101407893 0.27 ENST00000676156.1
ENST00000675592.1
ENST00000674634.2
ENST00000649178.1
ENST00000218516.4
galactosidase alpha
chr2_-_110115811 0.27 ENST00000272462.3
mal, T cell differentiation protein like
chr1_+_152908538 0.27 ENST00000368764.4
involucrin
chr19_-_51001591 0.27 ENST00000391806.6
kallikrein related peptidase 8
chr8_+_32646838 0.27 ENST00000651333.1
ENST00000652592.1
neuregulin 1
chr4_-_11428868 0.27 ENST00000002596.6
heparan sulfate-glucosamine 3-sulfotransferase 1
chr14_-_99271485 0.26 ENST00000345514.2
ENST00000443726.2
BAF chromatin remodeling complex subunit BCL11B
chr16_-_31135699 0.26 ENST00000317508.11
ENST00000568261.5
ENST00000567797.1
serine protease 8
chrX_+_72069659 0.26 ENST00000631375.1
NHS like 2
chr1_+_94820595 0.25 ENST00000467909.5
ENST00000422520.6
ENST00000532427.5
solute carrier family 44 member 3
chr12_-_52949818 0.25 ENST00000546897.5
ENST00000552551.5
keratin 8
chr4_-_80073057 0.25 ENST00000681710.1
ANTXR cell adhesion molecule 2
chr1_+_2073986 0.25 ENST00000461106.6
protein kinase C zeta
chr14_-_53956811 0.25 ENST00000559087.5
ENST00000245451.9
bone morphogenetic protein 4
chr1_+_209686173 0.25 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chrX_+_153687918 0.24 ENST00000253122.10
solute carrier family 6 member 8
chr12_+_82686889 0.24 ENST00000321196.8
transmembrane O-mannosyltransferase targeting cadherins 2
chr12_-_23949642 0.24 ENST00000537393.5
ENST00000451604.7
ENST00000381381.6
SRY-box transcription factor 5
chr11_-_74731385 0.24 ENST00000622063.4
ENST00000376332.8
chordin like 2
chr8_+_119208322 0.24 ENST00000614891.5
mal, T cell differentiation protein 2
chr4_-_80073170 0.24 ENST00000403729.7
ANTXR cell adhesion molecule 2
chr3_+_189631373 0.24 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chr12_+_20695323 0.23 ENST00000266509.7
solute carrier organic anion transporter family member 1C1
chr14_+_22112280 0.23 ENST00000390454.2
T cell receptor alpha variable 25
chr10_+_73911104 0.22 ENST00000446342.5
ENST00000372764.4
plasminogen activator, urokinase
chr12_+_100794769 0.22 ENST00000392977.8
ENST00000546991.1
ENST00000392979.7
anoctamin 4
chr11_-_74731148 0.22 ENST00000263671.9
ENST00000528789.1
chordin like 2
chr11_-_5301946 0.22 ENST00000380224.2
olfactory receptor family 51 subfamily B member 4
chr5_+_36608146 0.22 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr11_-_124441158 0.22 ENST00000328064.2
olfactory receptor family 8 subfamily B member 8
chr3_-_125120813 0.22 ENST00000430155.6
solute carrier family 12 member 8
chr17_+_7435416 0.22 ENST00000323206.2
ENST00000396568.1
transmembrane protein 102
chr7_+_144003929 0.22 ENST00000408922.3
olfactory receptor family 6 subfamily B member 1
chr17_+_7630094 0.21 ENST00000441599.6
ENST00000380450.9
ENST00000416273.7
ENST00000575903.5
ENST00000571153.5
ENST00000575618.5
ENST00000576152.1
ENST00000576830.5
sex hormone binding globulin
chr9_+_114155526 0.21 ENST00000356083.8
collagen type XXVII alpha 1 chain
chr1_-_153549238 0.21 ENST00000368713.8
S100 calcium binding protein A3
chr12_-_70637405 0.21 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
protein tyrosine phosphatase receptor type B
chr6_+_31575557 0.21 ENST00000449264.3
tumor necrosis factor
chr1_+_81800368 0.21 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr7_+_20330893 0.21 ENST00000222573.5
integrin subunit beta 8
chr9_-_122227525 0.21 ENST00000373755.6
ENST00000373754.6
LIM homeobox 6
chr1_+_92029971 0.21 ENST00000370383.5
epoxide hydrolase 4
chr4_-_80073465 0.21 ENST00000404191.5
ANTXR cell adhesion molecule 2
chr6_-_41163103 0.20 ENST00000373122.8
ENST00000373113.8
triggering receptor expressed on myeloid cells 2
chrX_+_48683763 0.20 ENST00000376701.5
WASP actin nucleation promoting factor
chr19_-_55149193 0.20 ENST00000587758.5
ENST00000588981.6
ENST00000356783.9
ENST00000291901.12
ENST00000588426.5
ENST00000536926.5
ENST00000588147.5
troponin T1, slow skeletal type
chr4_+_80197493 0.20 ENST00000415738.3
PR/SET domain 8
chr6_-_136525961 0.19 ENST00000438100.6
microtubule associated protein 7
chr4_-_80072993 0.19 ENST00000681115.1
ANTXR cell adhesion molecule 2
chr5_-_16508858 0.19 ENST00000684456.1
reticulophagy regulator 1
chr1_+_186828941 0.19 ENST00000367466.4
phospholipase A2 group IVA
chr17_+_36103819 0.19 ENST00000615863.2
ENST00000621626.1
C-C motif chemokine ligand 4
chr6_+_125219804 0.19 ENST00000524679.1
TPD52 like 1
chr1_+_156154371 0.19 ENST00000368282.1
semaphorin 4A
chr1_+_62597510 0.19 ENST00000371129.4
angiopoietin like 3
chr18_-_55510753 0.18 ENST00000543082.5
transcription factor 4
chr1_-_28176665 0.18 ENST00000373857.8
platelet activating factor receptor
chr17_-_48590231 0.18 ENST00000476342.1
ENST00000460160.5
ENST00000498678.6
ENST00000472863.5
homeobox B3
chr19_+_45001430 0.18 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr7_+_121873089 0.18 ENST00000651065.1
protein tyrosine phosphatase receptor type Z1
chr5_-_16508812 0.18 ENST00000683414.1
reticulophagy regulator 1
chr14_+_61321571 0.18 ENST00000332981.11
protein kinase C eta
chr5_-_16508951 0.18 ENST00000682628.1
reticulophagy regulator 1
chr8_+_22059198 0.18 ENST00000523266.5
ENST00000519907.5
dematin actin binding protein
chr7_-_16804987 0.17 ENST00000401412.5
ENST00000419304.7
anterior gradient 2, protein disulphide isomerase family member
chrX_+_106726663 0.17 ENST00000255499.3
ring finger protein 128
chr3_-_134029914 0.17 ENST00000493729.5
ENST00000310926.11
solute carrier organic anion transporter family member 2A1
chr4_-_76023489 0.17 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr12_+_1970772 0.17 ENST00000682544.1
calcium voltage-gated channel subunit alpha1 C
chr5_-_16508990 0.17 ENST00000399793.6
reticulophagy regulator 1
chr6_+_106086316 0.17 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr3_+_189789734 0.17 ENST00000437221.5
ENST00000392463.6
ENST00000392461.7
ENST00000449992.5
ENST00000456148.1
tumor protein p63
chr12_+_1970809 0.17 ENST00000683781.1
ENST00000682462.1
calcium voltage-gated channel subunit alpha1 C
chr1_+_160400543 0.16 ENST00000368061.3
VANGL planar cell polarity protein 2
chr13_+_112979306 0.16 ENST00000421756.5
MCF.2 cell line derived transforming sequence like
chr5_-_16508788 0.16 ENST00000682142.1
reticulophagy regulator 1
chr1_+_117001744 0.16 ENST00000256652.8
ENST00000682167.1
ENST00000369470.1
CD101 molecule
chr1_+_13583762 0.16 ENST00000376057.8
ENST00000621990.5
ENST00000510906.5
podoplanin
chrX_-_55030970 0.16 ENST00000493869.2
ENST00000396198.7
ENST00000650242.1
ENST00000335854.8
ENST00000477869.6
ENST00000455688.2
ENST00000644983.1
5'-aminolevulinate synthase 2
chr6_-_47042260 0.16 ENST00000371243.2
adhesion G protein-coupled receptor F1
chr9_-_114806031 0.16 ENST00000374045.5
TNF superfamily member 15
chr4_+_30720348 0.16 ENST00000361762.3
protocadherin 7
chr20_-_56525925 0.16 ENST00000243913.8
glucosaminyl (N-acetyl) transferase family member 7
chr17_+_75721327 0.16 ENST00000579662.5
integrin subunit beta 4
chr5_-_140633167 0.16 ENST00000302014.11
CD14 molecule
chr3_+_111911604 0.16 ENST00000495180.1
pleckstrin homology like domain family B member 2
chr6_+_33620329 0.16 ENST00000374316.9
inositol 1,4,5-trisphosphate receptor type 3
chr14_+_22836574 0.16 ENST00000548162.2
ENST00000311852.11
matrix metallopeptidase 14
chr6_-_56642788 0.16 ENST00000439203.5
ENST00000518935.5
ENST00000370765.11
ENST00000244364.10
dystonin
chrX_-_119837918 0.16 ENST00000636792.1
UPF3B regulator of nonsense mediated mRNA decay
chr7_+_117020191 0.16 ENST00000434836.5
ENST00000393443.5
ENST00000465133.5
ENST00000477742.5
ENST00000393444.7
ENST00000393447.8
suppression of tumorigenicity 7
chr3_-_139539679 0.15 ENST00000483943.6
ENST00000672186.1
ENST00000232219.6
ENST00000617459.4
ENST00000492918.1
retinol binding protein 1
chr11_+_65787056 0.15 ENST00000335987.8
ovo like transcriptional repressor 1
chr18_-_55302613 0.15 ENST00000561831.7
transcription factor 4
chr19_+_49335396 0.15 ENST00000598095.5
ENST00000426897.6
ENST00000323906.9
ENST00000535669.6
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr6_-_10412367 0.15 ENST00000379608.9
transcription factor AP-2 alpha
chr3_-_108058361 0.15 ENST00000398258.7
CD47 molecule
chr8_+_55879818 0.15 ENST00000520220.6
ENST00000519728.6
LYN proto-oncogene, Src family tyrosine kinase
chr15_+_76995118 0.15 ENST00000558012.6
ENST00000379595.7
proline-serine-threonine phosphatase interacting protein 1
chr6_+_137871208 0.15 ENST00000614035.4
ENST00000621150.3
ENST00000619035.4
ENST00000615468.4
ENST00000620204.3
TNF alpha induced protein 3
chr13_+_77535669 0.15 ENST00000535157.5
sciellin
chr4_+_83536097 0.15 ENST00000395226.6
ENST00000264409.5
glycerol-3-phosphate acyltransferase 3
chr19_+_51225059 0.14 ENST00000436584.6
ENST00000421133.6
ENST00000262262.5
ENST00000391796.7
CD33 molecule
chr7_+_20330678 0.14 ENST00000537992.5
integrin subunit beta 8
chr5_-_141878396 0.14 ENST00000503492.5
ENST00000287008.8
ENST00000394536.4
protocadherin 1
chr11_-_115504389 0.14 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
cell adhesion molecule 1
chr8_+_127736046 0.14 ENST00000641036.1
ENST00000377970.6
MYC proto-oncogene, bHLH transcription factor
chr2_-_74440484 0.14 ENST00000305557.9
ENST00000233330.6
rhotekin
chr1_-_115768702 0.14 ENST00000261448.6
calsequestrin 2
chr20_-_63653413 0.14 ENST00000370053.3
stathmin 3
chr13_+_77535681 0.14 ENST00000349847.4
sciellin
chr13_+_77535742 0.14 ENST00000377246.7
sciellin
chr17_+_7650916 0.14 ENST00000250111.9
ATPase Na+/K+ transporting subunit beta 2
chr14_-_23154369 0.14 ENST00000453702.5
solute carrier family 7 member 8
chr6_+_142301926 0.13 ENST00000296932.13
ENST00000367609.8
adhesion G protein-coupled receptor G6
chr18_+_44700796 0.13 ENST00000677130.1
SET binding protein 1
chr18_-_31162849 0.13 ENST00000257197.7
ENST00000257198.6
desmocollin 1
chr1_-_153549120 0.13 ENST00000368712.1
S100 calcium binding protein A3
chr1_-_27155118 0.13 ENST00000263980.8
solute carrier family 9 member A1
chr1_-_110064916 0.13 ENST00000649954.1
ALX homeobox 3
chr18_+_58221535 0.13 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr6_-_6006878 0.13 ENST00000244766.7
neuritin 1
chr20_+_1895365 0.13 ENST00000358771.5
signal regulatory protein alpha
chr7_-_141946926 0.13 ENST00000438351.1
ENST00000439991.1
ENST00000551012.6
ENST00000546910.6
C-type lectin domain containing 5A
chr5_+_148202771 0.13 ENST00000514389.5
ENST00000621437.4
serine peptidase inhibitor Kazal type 6
chr11_-_133532493 0.13 ENST00000524381.6
opioid binding protein/cell adhesion molecule like
chr4_+_24795560 0.13 ENST00000382120.4
superoxide dismutase 3
chr5_+_141051374 0.13 ENST00000306549.6
protocadherin beta 1
chr3_-_169663704 0.13 ENST00000651503.2
ENST00000494292.6
ENST00000486748.2
MDS1 and EVI1 complex locus
chrX_-_152451273 0.13 ENST00000370314.9
gamma-aminobutyric acid type A receptor subunit alpha3
chr5_+_35856883 0.12 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr3_+_50269140 0.12 ENST00000616701.5
ENST00000433753.4
ENST00000611067.4
semaphorin 3B
chr14_-_37595224 0.12 ENST00000250448.5
forkhead box A1
chr17_-_2336435 0.12 ENST00000301364.10
ENST00000576112.2
TSR1 ribosome maturation factor
chr13_-_51974775 0.12 ENST00000674147.1
ATPase copper transporting beta
chr7_-_101237827 0.12 ENST00000611078.4
claudin 15
chrX_-_24647300 0.12 ENST00000379144.7
phosphate cytidylyltransferase 1, choline, beta
chr13_-_46182136 0.12 ENST00000323076.7
lymphocyte cytosolic protein 1
chr3_+_113211459 0.12 ENST00000495514.5
BOC cell adhesion associated, oncogene regulated
chr1_+_81306096 0.12 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
adhesion G protein-coupled receptor L2

Network of associatons between targets according to the STRING database.

First level regulatory network of EZH2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.4 1.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 0.7 GO:0032289 central nervous system myelin formation(GO:0032289)
0.2 0.7 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.4 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.3 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.9 GO:0061709 reticulophagy(GO:0061709)
0.1 0.3 GO:0051695 actin filament uncapping(GO:0051695)
0.1 0.2 GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.1 0.3 GO:0003193 pulmonary valve formation(GO:0003193) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.1 1.4 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.3 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.4 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.3 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.3 GO:0035627 ceramide transport(GO:0035627)
0.1 0.5 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.2 GO:2000006 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.2 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 1.1 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.2 GO:0060559 regulation of translational initiation by iron(GO:0006447) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.2 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.2 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.1 1.8 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.1 0.8 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.3 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.6 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 0.2 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.1 0.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.2 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.0 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 1.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.2 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.1 GO:1903281 regulation of the force of heart contraction by cardiac conduction(GO:0086092) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0060003 copper ion export(GO:0060003)
0.0 0.2 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.2 GO:1990834 response to odorant(GO:1990834)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0045410 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) positive regulation of interleukin-6 biosynthetic process(GO:0045410) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) positive regulation of leukocyte tethering or rolling(GO:1903238)
0.0 0.2 GO:0010820 regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:1904799 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.2 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.1 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.1 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
0.0 0.1 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.2 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.6 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.1 GO:0048867 stem cell fate determination(GO:0048867)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.3 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 2.0 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.3 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023) activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.1 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:2001248 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.0 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.0 0.3 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:2000523 negative regulation of T-helper 1 cell differentiation(GO:0045626) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:2000078 glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.2 GO:0009449 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:2000329 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.1 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.0 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.3 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.0 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.1 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.2 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760) positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.0 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.0 GO:0071931 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.0 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.0 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.9 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.0 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.0 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.0 0.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.3 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.6 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.0 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.0 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.0 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)
0.0 1.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.1 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 1.0 GO:0072534 perineuronal net(GO:0072534)
0.1 0.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.2 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 1.8 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.6 GO:0043203 axon hillock(GO:0043203)
0.0 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.0 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.0 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.0 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.0 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.0 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.4 GO:0070821 tertiary granule membrane(GO:0070821)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.3 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 1.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.3 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.1 0.3 GO:0016936 galactoside binding(GO:0016936)
0.1 0.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.3 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 1.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.8 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.4 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0090422 thiamine pyrophosphate transporter activity(GO:0090422)
0.0 0.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.4 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.7 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.1 GO:0036505 prosaposin receptor activity(GO:0036505)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0047977 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.0 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.0 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.0 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.0 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.0 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 2.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.1 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC