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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for FLI1

Z-value: 0.44

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Transcription factors associated with FLI1

Gene Symbol Gene ID Gene Info
FLI1
ENSG00000151702.17 Fli-1 proto-oncogene, ETS transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FLI1hg38_v1_chr11_+_128694052_128694108,
hg38_v1_chr11_+_128693887_128693931		-0.686.4e-02Click!

Activity profile of FLI1 motif

Sorted Z-values of FLI1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_31321152 0.54 ENST00000446923.7
ZEB1
zinc finger E-box binding homeobox 1
chr5_+_95731300 0.35 ENST00000379982.8
RHOBTB3
Rho related BTB domain containing 3
chr7_+_100602344 0.34 ENST00000223061.6
PCOLCE
procollagen C-endopeptidase enhancer
chr17_-_19387170 0.33 ENST00000395592.6
ENST00000299610.5
MFAP4
microfibril associated protein 4
chr17_-_55732074 0.32 ENST00000575734.5
TMEM100
transmembrane protein 100
chr1_+_183805105 0.28 ENST00000360851.4
RGL1
ral guanine nucleotide dissociation stimulator like 1
chr2_-_187554351 0.27 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
TFPI
tissue factor pathway inhibitor
chr2_-_224982420 0.27 ENST00000645028.1
DOCK10
dedicator of cytokinesis 10
chr2_-_224947030 0.26 ENST00000409592.7
DOCK10
dedicator of cytokinesis 10
chr5_+_157266079 0.26 ENST00000616178.4
ENST00000522463.5
ENST00000435847.6
ENST00000620254.5
ENST00000521420.5
ENST00000617629.4
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr1_-_153545793 0.26 ENST00000354332.8
ENST00000368716.9
S100A4
S100 calcium binding protein A4
chr2_-_237414127 0.25 ENST00000472056.5
COL6A3
collagen type VI alpha 3 chain
chr2_-_237414157 0.24 ENST00000295550.9
ENST00000353578.9
ENST00000392004.7
ENST00000433762.1
ENST00000392003.6
COL6A3
collagen type VI alpha 3 chain
chr10_+_69088096 0.24 ENST00000242465.4
SRGN
serglycin
chr10_+_68106109 0.24 ENST00000540630.5
ENST00000354393.6
MYPN
myopalladin
chr14_-_105940235 0.20 ENST00000390593.2
IGHV6-1
immunoglobulin heavy variable 6-1
chr1_+_159204860 0.20 ENST00000368122.4
ENST00000368121.6
ACKR1
atypical chemokine receptor 1 (Duffy blood group)
chr1_+_154327737 0.19 ENST00000672630.1
ATP8B2
ATPase phospholipid transporting 8B2
chr13_-_33185994 0.18 ENST00000255486.8
STARD13
StAR related lipid transfer domain containing 13
chr12_-_108339300 0.18 ENST00000550402.6
ENST00000552995.5
ENST00000312143.11
CMKLR1
chemerin chemokine-like receptor 1
chr3_-_122022122 0.18 ENST00000393631.5
ENST00000273691.7
ENST00000344209.10
ILDR1
immunoglobulin like domain containing receptor 1
chr4_+_54229261 0.18 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
PDGFRA
platelet derived growth factor receptor alpha
chr5_-_76623391 0.18 ENST00000296641.5
ENST00000504899.1
F2RL2
coagulation factor II thrombin receptor like 2
chr1_+_15305735 0.18 ENST00000375997.8
ENST00000524761.5
ENST00000375995.3
FHAD1
forkhead associated phosphopeptide binding domain 1
chr2_-_68319887 0.18 ENST00000409862.1
ENST00000263655.4
CNRIP1
cannabinoid receptor interacting protein 1
chr5_-_147401591 0.17 ENST00000520473.1
DPYSL3
dihydropyrimidinase like 3
chr18_-_54959391 0.17 ENST00000591504.6
CCDC68
coiled-coil domain containing 68
chr8_-_13514821 0.17 ENST00000276297.9
DLC1
DLC1 Rho GTPase activating protein
chr13_+_75788838 0.17 ENST00000497947.6
LMO7
LIM domain 7
chr6_-_52577012 0.16 ENST00000182527.4
TRAM2
translocation associated membrane protein 2
chr1_-_153544997 0.16 ENST00000368715.5
S100A4
S100 calcium binding protein A4
chr3_+_148697784 0.16 ENST00000497524.5
ENST00000418473.7
ENST00000349243.8
ENST00000404754.2
AGTR1
angiotensin II receptor type 1
chr21_+_42653734 0.16 ENST00000335512.8
ENST00000328862.10
ENST00000335440.10
ENST00000380328.6
ENST00000398225.7
ENST00000398227.7
ENST00000398229.7
ENST00000398232.7
ENST00000398234.7
ENST00000398236.7
ENST00000349112.7
ENST00000398224.3
PDE9A
phosphodiesterase 9A
chr17_-_68601357 0.16 ENST00000592554.2
FAM20A
FAM20A golgi associated secretory pathway pseudokinase
chr4_-_107036302 0.16 ENST00000285311.8
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr9_+_87498491 0.16 ENST00000622514.4
DAPK1
death associated protein kinase 1
chr11_-_82997394 0.15 ENST00000525117.5
ENST00000532548.5
RAB30
RAB30, member RAS oncogene family
chr5_+_68288346 0.15 ENST00000320694.12
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
chr2_-_174597795 0.15 ENST00000679041.1
WIPF1
WAS/WASL interacting protein family member 1
chr1_-_167090370 0.15 ENST00000367868.4
GPA33
glycoprotein A33
chr3_-_58577367 0.14 ENST00000464064.5
ENST00000360997.7
FAM107A
family with sequence similarity 107 member A
chr2_-_174634566 0.14 ENST00000392547.6
WIPF1
WAS/WASL interacting protein family member 1
chr21_-_38121331 0.14 ENST00000482032.1
ENST00000398948.5
ENST00000328264.7
ENST00000645093.1
DSCR4
KCNJ6
Down syndrome critical region 4
potassium inwardly rectifying channel subfamily J member 6
chr3_-_195583931 0.14 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
APOD
apolipoprotein D
chr11_-_82997477 0.14 ENST00000534301.5
RAB30
RAB30, member RAS oncogene family
chr12_+_53046969 0.14 ENST00000379902.7
TNS2
tensin 2
chr9_+_76459152 0.14 ENST00000444201.6
ENST00000376730.5
GCNT1
glucosaminyl (N-acetyl) transferase 1
chr5_+_141359970 0.14 ENST00000522605.2
ENST00000622527.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr1_-_85578345 0.13 ENST00000426972.8
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr10_-_126388455 0.13 ENST00000368679.8
ENST00000368676.8
ENST00000448723.2
ADAM12
ADAM metallopeptidase domain 12
chr14_+_100376398 0.13 ENST00000554998.5
ENST00000402312.8
ENST00000335290.10
ENST00000554175.5
WDR25
WD repeat domain 25
chr5_+_150672057 0.13 ENST00000520112.1
MYOZ3
myozenin 3
chr4_-_184825960 0.13 ENST00000281455.7
ACSL1
acyl-CoA synthetase long chain family member 1
chr10_-_43574555 0.13 ENST00000374446.7
ENST00000535642.5
ENST00000426961.1
ZNF239
zinc finger protein 239
chr10_-_79445617 0.13 ENST00000372336.4
ZCCHC24
zinc finger CCHC-type containing 24
chr4_-_184826030 0.13 ENST00000507295.5
ENST00000504900.5
ENST00000454703.6
ACSL1
acyl-CoA synthetase long chain family member 1
chr7_+_93921720 0.13 ENST00000248564.6
GNG11
G protein subunit gamma 11
chr8_+_38820332 0.13 ENST00000518809.5
ENST00000520611.1
TACC1
transforming acidic coiled-coil containing protein 1
chr16_-_3305397 0.13 ENST00000396862.2
TIGD7
tigger transposable element derived 7
chr3_-_58577648 0.12 ENST00000394481.5
FAM107A
family with sequence similarity 107 member A
chr7_+_101127095 0.12 ENST00000223095.5
SERPINE1
serpin family E member 1
chr8_+_22565236 0.12 ENST00000523900.5
SORBS3
sorbin and SH3 domain containing 3
chr6_+_72212887 0.12 ENST00000523963.5
RIMS1
regulating synaptic membrane exocytosis 1
chr2_-_187554473 0.12 ENST00000453013.5
ENST00000417013.5
TFPI
tissue factor pathway inhibitor
chr3_+_9902619 0.12 ENST00000421412.5
IL17RE
interleukin 17 receptor E
chr8_+_38728550 0.12 ENST00000520340.5
ENST00000518415.5
TACC1
transforming acidic coiled-coil containing protein 1
chr14_+_51860391 0.12 ENST00000335281.8
GNG2
G protein subunit gamma 2
chr6_+_72212802 0.12 ENST00000401910.7
RIMS1
regulating synaptic membrane exocytosis 1
chr2_-_199458689 0.12 ENST00000443023.5
SATB2
SATB homeobox 2
chr9_+_2017383 0.11 ENST00000382194.6
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_+_1056776 0.11 ENST00000650072.1
WDR37
WD repeat domain 37
chr16_+_53208438 0.11 ENST00000565442.1
CHD9
chromodomain helicase DNA binding protein 9
chr5_+_181223270 0.11 ENST00000315073.10
ENST00000351937.9
TRIM41
tripartite motif containing 41
chr7_+_142855060 0.11 ENST00000619012.4
ENST00000652003.1
EPHB6
EPH receptor B6
chr8_-_13514744 0.11 ENST00000316609.9
DLC1
DLC1 Rho GTPase activating protein
chr16_+_20806517 0.11 ENST00000348433.10
ENST00000568501.5
ENST00000261377.11
ENST00000566276.5
REXO5
RNA exonuclease 5
chr2_-_197310646 0.11 ENST00000647377.1
ANKRD44
ankyrin repeat domain 44
chr5_-_151686908 0.11 ENST00000231061.9
SPARC
secreted protein acidic and cysteine rich
chr17_+_68512878 0.11 ENST00000585981.5
ENST00000589480.5
ENST00000585815.5
PRKAR1A
protein kinase cAMP-dependent type I regulatory subunit alpha
chr6_-_56851888 0.11 ENST00000312431.10
ENST00000520645.5
DST
dystonin
chr7_+_48171451 0.11 ENST00000435803.6
ABCA13
ATP binding cassette subfamily A member 13
chr1_+_84144260 0.11 ENST00000370685.7
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr2_+_165294031 0.10 ENST00000283256.10
SCN2A
sodium voltage-gated channel alpha subunit 2
chr12_-_105236074 0.10 ENST00000551662.5
ENST00000553097.5
ENST00000258530.8
APPL2
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
chr9_-_35732122 0.10 ENST00000314888.10
TLN1
talin 1
chr5_-_36066874 0.10 ENST00000282507.8
ENST00000513300.5
UGT3A2
UDP glycosyltransferase family 3 member A2
chr17_+_68512379 0.10 ENST00000392711.5
ENST00000585427.5
ENST00000589228.6
ENST00000536854.6
ENST00000588702.5
ENST00000589309.5
PRKAR1A
protein kinase cAMP-dependent type I regulatory subunit alpha
chr9_-_137028878 0.10 ENST00000625103.1
ENST00000614293.4
ABCA2
ATP binding cassette subfamily A member 2
chr2_+_64989343 0.10 ENST00000234256.4
SLC1A4
solute carrier family 1 member 4
chr2_+_65228122 0.10 ENST00000542850.2
ACTR2
actin related protein 2
chrX_+_51803007 0.10 ENST00000375772.7
MAGED1
MAGE family member D1
chr2_-_199457931 0.10 ENST00000417098.6
SATB2
SATB homeobox 2
chr14_-_100376251 0.10 ENST00000556645.5
ENST00000556209.5
ENST00000556504.5
ENST00000556435.5
ENST00000554772.5
ENST00000553581.1
ENST00000553769.6
ENST00000554605.5
ENST00000557722.5
ENST00000553413.5
ENST00000553524.5
ENST00000358655.8
WARS1
tryptophanyl-tRNA synthetase 1
chr3_+_48465811 0.10 ENST00000433541.1
ENST00000444177.1
TREX1
three prime repair exonuclease 1
chr4_+_159241016 0.10 ENST00000644902.1
RAPGEF2
Rap guanine nucleotide exchange factor 2
chr14_+_105486867 0.10 ENST00000409393.6
ENST00000392531.4
CRIP1
cysteine rich protein 1
chr15_+_92900338 0.10 ENST00000625990.3
CHD2
chromodomain helicase DNA binding protein 2
chr17_-_37542361 0.10 ENST00000614196.1
SYNRG
synergin gamma
chr9_+_18474100 0.10 ENST00000327883.11
ENST00000431052.6
ENST00000380570.8
ENST00000380548.9
ADAMTSL1
ADAMTS like 1
chr16_+_20806698 0.10 ENST00000564274.5
ENST00000563068.1
REXO5
RNA exonuclease 5
chr12_+_54028433 0.10 ENST00000243108.5
HOXC6
homeobox C6
chr9_+_18474206 0.10 ENST00000276935.6
ADAMTSL1
ADAMTS like 1
chr16_+_1528674 0.10 ENST00000253934.9
TMEM204
transmembrane protein 204
chr19_+_15107369 0.10 ENST00000342784.7
ENST00000597977.5
ENST00000600440.5
SYDE1
synapse defective Rho GTPase homolog 1
chr19_+_56567461 0.10 ENST00000330619.13
ZNF470
zinc finger protein 470
chr12_+_93677556 0.09 ENST00000542893.2
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr12_+_93677352 0.09 ENST00000552983.5
ENST00000332896.8
ENST00000552033.5
ENST00000548483.5
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr3_+_51942323 0.09 ENST00000431474.6
ENST00000417220.6
ENST00000398755.8
ENST00000471971.6
PARP3
poly(ADP-ribose) polymerase family member 3
chr2_-_165203870 0.09 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
SCN3A
sodium voltage-gated channel alpha subunit 3
chr8_+_232416 0.09 ENST00000518414.5
ENST00000521270.5
ENST00000518320.6
ENST00000398612.3
ZNF596
zinc finger protein 596
chrX_+_54808334 0.09 ENST00000218439.8
MAGED2
MAGE family member D2
chr6_+_52420992 0.09 ENST00000636954.1
ENST00000636566.1
ENST00000638075.1
EFHC1
EF-hand domain containing 1
chr2_+_102104563 0.09 ENST00000409589.5
ENST00000409329.5
IL1R1
interleukin 1 receptor type 1
chr6_-_129710145 0.09 ENST00000368149.3
ARHGAP18
Rho GTPase activating protein 18
chr19_-_49813151 0.09 ENST00000528094.5
ENST00000526575.1
FUZ
fuzzy planar cell polarity protein
chr12_-_10454485 0.09 ENST00000408006.7
ENST00000544822.2
ENST00000536188.5
KLRC1
killer cell lectin like receptor C1
chr2_+_201451711 0.09 ENST00000194530.8
ENST00000392249.6
STRADB
STE20 related adaptor beta
chr14_+_20891385 0.09 ENST00000304639.4
RNASE3
ribonuclease A family member 3
chr2_-_201451446 0.09 ENST00000332624.8
ENST00000430254.1
TRAK2
trafficking kinesin protein 2
chr21_+_43865200 0.09 ENST00000291572.13
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chrX_-_56995426 0.09 ENST00000640768.1
ENST00000638619.1
SPIN3
spindlin family member 3
chr1_-_153550083 0.09 ENST00000368714.1
S100A4
S100 calcium binding protein A4
chr14_+_105314711 0.09 ENST00000447393.6
ENST00000547217.5
PACS2
phosphofurin acidic cluster sorting protein 2
chr12_-_10453330 0.09 ENST00000347831.9
ENST00000359151.8
KLRC1
killer cell lectin like receptor C1
chr9_+_2621556 0.09 ENST00000680746.1
VLDLR
very low density lipoprotein receptor
chr2_+_108621260 0.09 ENST00000409441.5
LIMS1
LIM zinc finger domain containing 1
chr9_+_137788781 0.09 ENST00000482340.5
EHMT1
euchromatic histone lysine methyltransferase 1
chr6_+_131808011 0.09 ENST00000647893.1
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr3_+_29281049 0.09 ENST00000383767.7
RBMS3
RNA binding motif single stranded interacting protein 3
chr8_+_232137 0.09 ENST00000521145.5
ENST00000320552.6
ENST00000308811.8
ENST00000640035.1
ENST00000522866.5
ZNF596
zinc finger protein 596
chr11_-_2137277 0.09 ENST00000381392.5
ENST00000381395.5
ENST00000418738.2
IGF2
insulin like growth factor 2
chr15_-_52652031 0.09 ENST00000546305.6
FAM214A
family with sequence similarity 214 member A
chr3_+_29280945 0.09 ENST00000434693.6
RBMS3
RNA binding motif single stranded interacting protein 3
chrX_+_54808359 0.09 ENST00000375058.5
ENST00000375060.5
MAGED2
MAGE family member D2
chrX_-_56995508 0.08 ENST00000374919.6
ENST00000639007.1
ENST00000639583.1
ENST00000638289.1
ENST00000639525.1
ENST00000638386.1
SPIN3
spindlin family member 3
chr2_-_152175715 0.08 ENST00000263904.5
STAM2
signal transducing adaptor molecule 2
chr6_+_31586859 0.08 ENST00000433492.5
LST1
leukocyte specific transcript 1
chr19_-_49813223 0.08 ENST00000533418.5
FUZ
fuzzy planar cell polarity protein
chr2_-_165204042 0.08 ENST00000283254.12
ENST00000453007.1
SCN3A
sodium voltage-gated channel alpha subunit 3
chr9_+_2621766 0.08 ENST00000382100.8
VLDLR
very low density lipoprotein receptor
chr11_-_417385 0.08 ENST00000332725.7
SIGIRR
single Ig and TIR domain containing
chr12_+_21526287 0.08 ENST00000256969.7
SPX
spexin hormone
chr8_+_38728186 0.08 ENST00000519416.5
ENST00000520615.5
TACC1
transforming acidic coiled-coil containing protein 1
chr11_+_35662739 0.08 ENST00000299413.7
TRIM44
tripartite motif containing 44
chr2_-_127642131 0.08 ENST00000426981.5
LIMS2
LIM zinc finger domain containing 2
chr5_+_138084015 0.08 ENST00000504809.5
ENST00000506684.6
ENST00000398754.1
WNT8A
Wnt family member 8A
chr12_+_112418889 0.08 ENST00000392597.5
PTPN11
protein tyrosine phosphatase non-receptor type 11
chr14_+_88005128 0.08 ENST00000267549.5
GPR65
G protein-coupled receptor 65
chr16_+_69566041 0.08 ENST00000567239.5
NFAT5
nuclear factor of activated T cells 5
chr14_+_54567100 0.08 ENST00000554335.6
SAMD4A
sterile alpha motif domain containing 4A
chr4_-_139084289 0.08 ENST00000510408.5
ENST00000379549.7
ENST00000358635.7
ELF2
E74 like ETS transcription factor 2
chr5_-_124744513 0.08 ENST00000504926.5
ZNF608
zinc finger protein 608
chr5_-_138875290 0.08 ENST00000521094.2
ENST00000274711.7
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr1_-_159923717 0.08 ENST00000368096.5
TAGLN2
transgelin 2
chr5_+_68292562 0.08 ENST00000523872.1
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
chr12_-_15221394 0.08 ENST00000537647.5
ENST00000256953.6
ENST00000546331.5
RERG
RAS like estrogen regulated growth inhibitor
chr5_+_134905100 0.08 ENST00000512783.5
ENST00000254908.11
PCBD2
pterin-4 alpha-carbinolamine dehydratase 2
chr17_-_8376658 0.08 ENST00000643221.1
ENST00000647210.1
ENST00000649935.1
ENST00000396267.3
KRBA2
KRAB-A domain containing 2
chr11_-_417304 0.08 ENST00000397632.7
SIGIRR
single Ig and TIR domain containing
chr17_+_37375974 0.08 ENST00000615133.2
ENST00000611038.4
C17orf78
chromosome 17 open reading frame 78
chr9_-_136095268 0.08 ENST00000277554.4
NACC2
NACC family member 2
chr6_+_10555787 0.08 ENST00000316170.9
GCNT2
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr2_+_24076817 0.08 ENST00000613899.4
FAM228B
family with sequence similarity 228 member B
chrX_-_153446051 0.08 ENST00000370231.3
TREX2
three prime repair exonuclease 2
chr12_+_119667859 0.08 ENST00000541640.5
PRKAB1
protein kinase AMP-activated non-catalytic subunit beta 1
chr2_+_157257687 0.08 ENST00000259056.5
GALNT5
polypeptide N-acetylgalactosaminyltransferase 5
chr11_+_72080595 0.08 ENST00000647530.1
ENST00000539271.6
ENST00000642510.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr16_+_30896606 0.07 ENST00000279804.3
ENST00000395019.3
CTF1
cardiotrophin 1
chrX_+_86714623 0.07 ENST00000484479.1
DACH2
dachshund family transcription factor 2
chr2_+_188292771 0.07 ENST00000359135.7
GULP1
GULP PTB domain containing engulfment adaptor 1
chr3_+_119597874 0.07 ENST00000488919.5
ENST00000273371.9
ENST00000495992.5
PLA1A
phospholipase A1 member A
chr5_-_38595396 0.07 ENST00000263409.8
LIFR
LIF receptor subunit alpha
chrX_+_65588368 0.07 ENST00000609672.5
MSN
moesin
chr19_-_57578872 0.07 ENST00000196489.4
ZNF416
zinc finger protein 416
chr3_+_29281552 0.07 ENST00000452462.5
ENST00000456853.1
RBMS3
RNA binding motif single stranded interacting protein 3
chr19_-_10339610 0.07 ENST00000589261.5
ENST00000160262.10
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
ICAM3
intercellular adhesion molecule 3
chr19_+_12163049 0.07 ENST00000425827.5
ENST00000439995.5
ENST00000652580.1
ENST00000343979.6
ENST00000418338.1
ZNF136
zinc finger protein 136
chr5_+_103120264 0.07 ENST00000358359.8
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr20_-_47355657 0.07 ENST00000311275.11
ZMYND8
zinc finger MYND-type containing 8
chr1_-_36323593 0.07 ENST00000490466.2
EVA1B
eva-1 homolog B
chr10_-_49539112 0.07 ENST00000355832.10
ENST00000447839.7
ERCC6
ERCC excision repair 6, chromatin remodeling factor
chr10_-_49539015 0.07 ENST00000681659.1
ENST00000680107.1
ERCC6
ERCC excision repair 6, chromatin remodeling factor
chr19_-_49813259 0.07 ENST00000313777.9
FUZ
fuzzy planar cell polarity protein
chr2_+_201116143 0.07 ENST00000443227.5
ENST00000309955.8
ENST00000341222.10
ENST00000341582.10
CFLAR
CASP8 and FADD like apoptosis regulator
chr10_+_114821744 0.07 ENST00000369250.7
ENST00000369246.1
ENST00000369248.9
FAM160B1
family with sequence similarity 160 member B1
chr4_+_932426 0.07 ENST00000514453.5
ENST00000515492.5
ENST00000509508.5
ENST00000264771.9
ENST00000515740.5
ENST00000508204.5
ENST00000510493.5
ENST00000514546.5
ENST00000622959.3
TMEM175
transmembrane protein 175
chr20_+_36214373 0.07 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1 like 1
chr2_+_230327218 0.07 ENST00000243810.10
ENST00000396563.8
SP140L
SP140 nuclear body protein like
chr19_-_45424364 0.07 ENST00000589165.5
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit
chr1_+_23959109 0.07 ENST00000471915.5
PNRC2
proline rich nuclear receptor coactivator 2
chr2_+_230327160 0.07 ENST00000444636.5
ENST00000415673.7
SP140L
SP140 nuclear body protein like
chr6_+_25962792 0.07 ENST00000357085.5
TRIM38
tripartite motif containing 38
chr3_+_29281441 0.07 ENST00000273139.13
ENST00000383766.6
RBMS3
RNA binding motif single stranded interacting protein 3
chr2_-_24360445 0.07 ENST00000443927.5
ENST00000406921.7
ENST00000412011.5
ENST00000355123.9
ITSN2
intersectin 2
chr11_-_3165264 0.07 ENST00000389989.7
ENST00000263650.12
OSBPL5
oxysterol binding protein like 5
chr8_-_144787275 0.07 ENST00000343459.8
ENST00000429371.7
ENST00000534445.1
ZNF34
zinc finger protein 34
chr19_+_1908258 0.07 ENST00000411971.5
ENST00000588907.2
SCAMP4
secretory carrier membrane protein 4
chr19_+_57614211 0.07 ENST00000600344.1
ENST00000396161.10
ENST00000600883.1
ZNF134
zinc finger protein 134
chr4_-_76234509 0.07 ENST00000638295.1
SCARB2
scavenger receptor class B member 2
chr11_+_72080803 0.07 ENST00000423494.6
ENST00000539587.6
ENST00000536917.2
ENST00000538478.5
ENST00000324866.11
ENST00000643715.1
ENST00000439209.5
LRTOMT
ENSG00000284922.2
leucine rich transmembrane and O-methyltransferase domain containing
leucine rich transmembrane and O-methyltransferase domain containing

Network of associatons between targets according to the STRING database.

First level regulatory network of FLI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.6 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.2 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.2 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.2 GO:0044691 tooth eruption(GO:0044691)
0.0 0.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.0 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0039506 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.2 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.3 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0044335 canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335)
0.0 0.3 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.1 GO:0033594 response to hydroxyisoflavone(GO:0033594)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.1 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.0 0.0 GO:0050904 diapedesis(GO:0050904)
0.0 0.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.1 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.2 GO:0021678 third ventricle development(GO:0021678)
0.0 0.2 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0044007 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.0 0.3 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.2 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0046061 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.0 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.1 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.0 GO:0051463 negative regulation of cortisol secretion(GO:0051463)
0.0 0.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.0 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.0 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.0 GO:2001025 response to cyclosporin A(GO:1905237) positive regulation of response to drug(GO:2001025)
0.0 0.1 GO:1902228 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0035744 T-helper 1 cell cytokine production(GO:0035744)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.0 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.2 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.2 GO:0060992 response to fungicide(GO:0060992)
0.0 0.1 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.0 GO:1903248 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.1 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.0 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.1 GO:1904304 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.0 0.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.0 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.0 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.0 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.0 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.0 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.1 GO:0044714 GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
0.0 0.2 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.4 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.0 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.0 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.0 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.0 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.0 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling