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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for FOSB

Z-value: 1.95

Motif logo

Transcription factors associated with FOSB

Gene Symbol Gene ID Gene Info
ENSG00000125740.14 FosB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSBhg38_v1_chr19_+_45467988_45468007-0.423.0e-01Click!

Activity profile of FOSB motif

Sorted Z-values of FOSB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_23873000 5.63 ENST00000269217.11
ENST00000587184.5
laminin subunit alpha 3
chr19_-_35513641 1.97 ENST00000339686.8
ENST00000447113.6
dermokine
chr6_+_125219804 1.79 ENST00000524679.1
TPD52 like 1
chr3_-_151316795 1.77 ENST00000260843.5
G protein-coupled receptor 87
chr18_+_63775369 1.57 ENST00000540675.5
serpin family B member 7
chr17_-_41612757 1.48 ENST00000301653.9
ENST00000593067.1
keratin 16
chr15_+_40239042 1.40 ENST00000558055.5
ENST00000455577.6
p21 (RAC1) activated kinase 6
chr15_+_40239420 1.35 ENST00000560346.5
p21 (RAC1) activated kinase 6
chr19_-_35501878 1.34 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
dermokine
chr18_+_63775395 1.29 ENST00000398019.7
serpin family B member 7
chr11_-_102798148 1.23 ENST00000315274.7
matrix metallopeptidase 1
chr19_-_38773432 1.20 ENST00000599035.1
ENST00000378626.5
galectin 7
chr17_-_8118489 1.17 ENST00000380149.6
ENST00000448843.7
arachidonate lipoxygenase 3
chr2_+_102001966 1.04 ENST00000457817.5
interleukin 1 receptor type 2
chr5_+_145936554 1.02 ENST00000359120.9
SH3 domain containing ring finger 2
chr3_+_36380477 1.00 ENST00000457375.6
ENST00000273183.8
ENST00000434649.1
SH3 and cysteine rich domain
chr16_+_30740621 0.99 ENST00000615541.3
ENST00000483578.1
transmembrane protein 265
novel transcript
chr6_+_130366281 0.98 ENST00000617887.4
transmembrane protein 200A
chr20_+_46008900 0.91 ENST00000372330.3
matrix metallopeptidase 9
chr15_-_82952683 0.90 ENST00000450735.7
ENST00000304231.12
homer scaffold protein 2
chr1_+_152908538 0.87 ENST00000368764.4
involucrin
chr4_-_36244438 0.85 ENST00000303965.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_41786688 0.85 ENST00000310706.9
ENST00000393931.8
ENST00000424457.5
ENST00000591690.5
junction plakoglobin
chr7_-_20217342 0.83 ENST00000400331.10
ENST00000332878.8
MET transcriptional regulator MACC1
chr1_-_153057504 0.82 ENST00000392653.3
small proline rich protein 2A
chr6_+_130365958 0.81 ENST00000296978.4
transmembrane protein 200A
chr5_+_66828762 0.77 ENST00000490016.6
ENST00000403666.5
ENST00000450827.5
microtubule associated serine/threonine kinase family member 4
chr4_-_88158605 0.76 ENST00000237612.8
ATP binding cassette subfamily G member 2 (Junior blood group)
chr12_-_95116967 0.74 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr1_+_26543106 0.74 ENST00000530003.5
ribosomal protein S6 kinase A1
chr2_-_237590660 0.73 ENST00000409576.1
RAB17, member RAS oncogene family
chr14_-_94388589 0.73 ENST00000402629.1
ENST00000556091.1
ENST00000393087.9
ENST00000554720.1
serpin family A member 1
chr5_+_148203024 0.71 ENST00000325630.3
serine peptidase inhibitor Kazal type 6
chr15_-_44194407 0.68 ENST00000484674.5
FERM domain containing 5
chr5_+_145937793 0.67 ENST00000511217.1
SH3 domain containing ring finger 2
chr18_-_76495191 0.66 ENST00000443185.7
zinc finger protein 516
chr1_-_153549238 0.64 ENST00000368713.8
S100 calcium binding protein A3
chr14_-_23155302 0.63 ENST00000529705.6
solute carrier family 7 member 8
chr2_-_237590694 0.63 ENST00000264601.8
ENST00000411462.5
ENST00000409822.1
RAB17, member RAS oncogene family
chr6_-_138107412 0.62 ENST00000421351.4
p53 apoptosis effector related to PMP22
chr19_-_43670153 0.62 ENST00000601723.5
ENST00000339082.7
ENST00000340093.8
plasminogen activator, urokinase receptor
chr1_+_89364051 0.56 ENST00000370456.5
guanylate binding protein family member 6
chr11_+_128694052 0.54 ENST00000527786.7
ENST00000534087.3
Fli-1 proto-oncogene, ETS transcription factor
chr1_+_22007450 0.53 ENST00000400271.2
chymotrypsin like elastase 3A
chr1_-_12616762 0.52 ENST00000464917.5
dehydrogenase/reductase 3
chr11_+_128693887 0.52 ENST00000281428.12
Fli-1 proto-oncogene, ETS transcription factor
chr1_-_153549120 0.51 ENST00000368712.1
S100 calcium binding protein A3
chr17_-_19004727 0.50 ENST00000388995.11
family with sequence similarity 83 member G
chr4_+_83536097 0.50 ENST00000395226.6
ENST00000264409.5
glycerol-3-phosphate acyltransferase 3
chr1_-_153041111 0.49 ENST00000360379.4
small proline rich protein 2D
chr19_-_35490456 0.48 ENST00000338897.4
ENST00000484218.6
keratinocyte differentiation associated protein
chr17_+_75721451 0.46 ENST00000200181.8
integrin subunit beta 4
chr8_-_124372686 0.45 ENST00000297632.8
transmembrane protein 65
chr17_+_7440738 0.45 ENST00000575398.5
ENST00000575082.5
fibroblast growth factor 11
chr5_-_79514127 0.42 ENST00000334082.11
homer scaffold protein 1
chr1_-_32901330 0.42 ENST00000329151.5
ENST00000373463.8
transmembrane protein 54
chr11_-_2903490 0.42 ENST00000455942.3
ENST00000625099.4
solute carrier family 22 member 18 antisense
chr11_-_75490725 0.41 ENST00000529721.5
glycerophosphodiester phosphodiesterase domain containing 5
chr1_-_153094521 0.40 ENST00000368750.8
small proline rich protein 2E
chr19_+_7888499 0.39 ENST00000618098.4
ENST00000306708.11
ENST00000600345.1
ENST00000598224.5
leucine rich repeat containing 8 VRAC subunit E
chr5_+_148202771 0.39 ENST00000514389.5
ENST00000621437.4
serine peptidase inhibitor Kazal type 6
chr17_+_21288029 0.38 ENST00000526076.6
ENST00000361818.9
ENST00000316920.10
mitogen-activated protein kinase kinase 3
chr6_-_35921079 0.38 ENST00000507909.1
ENST00000373825.7
SRSF protein kinase 1
chr6_-_35921047 0.37 ENST00000361690.7
ENST00000512445.5
SRSF protein kinase 1
chrX_-_155334580 0.37 ENST00000369449.7
ENST00000321926.4
chloride intracellular channel 2
chr6_-_35921128 0.36 ENST00000510290.5
ENST00000423325.6
SRSF protein kinase 1
chr17_-_29176752 0.35 ENST00000533112.5
myosin XVIIIA
chr18_+_58196736 0.34 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr3_-_142029108 0.34 ENST00000497579.5
transcription factor Dp-2
chr6_+_150721073 0.33 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chr2_+_102418642 0.33 ENST00000264260.6
interleukin 18 receptor accessory protein
chr19_-_48511793 0.32 ENST00000600059.6
lemur tyrosine kinase 3
chr6_+_33075952 0.31 ENST00000418931.7
major histocompatibility complex, class II, DP beta 1
chr2_+_27014746 0.31 ENST00000648289.1
ENST00000458529.5
ENST00000402218.1
microtubule associated protein RP/EB family member 3
chr6_+_44227025 0.30 ENST00000371708.1
solute carrier family 29 member 1 (Augustine blood group)
chr1_+_27342014 0.30 ENST00000618673.4
ENST00000318074.9
ENST00000616558.5
synaptotagmin like 1
chr17_+_32444379 0.29 ENST00000578213.5
ENST00000649012.1
ENST00000457654.6
ENST00000579451.1
ENST00000261712.8
proteasome 26S subunit, non-ATPase 11
chr17_-_41140487 0.29 ENST00000345847.4
keratin associated protein 4-6
chr4_+_75556048 0.29 ENST00000616557.1
ENST00000435974.2
ENST00000311623.9
odontogenesis associated phosphoprotein
chr16_+_57628684 0.28 ENST00000567397.5
ENST00000568979.5
ENST00000672974.1
adhesion G protein-coupled receptor G1
chr12_-_94616061 0.28 ENST00000551457.1
transmembrane and coiled-coil domain family 3
chr22_+_31082860 0.28 ENST00000619644.4
smoothelin
chr6_+_47698574 0.27 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr11_+_706222 0.27 ENST00000318562.13
ENST00000533500.5
EPS8 like 2
chr18_-_55351977 0.27 ENST00000643689.1
transcription factor 4
chr19_-_55370455 0.26 ENST00000264563.7
ENST00000585513.1
ENST00000590625.5
interleukin 11
chr6_+_32153441 0.26 ENST00000414204.5
ENST00000361568.6
ENST00000395523.5
palmitoyl-protein thioesterase 2
chr17_+_37491464 0.26 ENST00000613659.1
dual specificity phosphatase 14
chr6_+_47698538 0.26 ENST00000327753.7
adhesion G protein-coupled receptor F4
chr11_-_123885627 0.25 ENST00000528595.1
ENST00000375026.7
transmembrane protein 225
chr1_+_247416149 0.25 ENST00000366497.6
ENST00000391828.8
NLR family pyrin domain containing 3
chr16_-_4614876 0.25 ENST00000591401.5
ENST00000283474.12
ENST00000591897.5
UBA like domain containing 1
chr11_+_706117 0.25 ENST00000533256.5
ENST00000614442.4
EPS8 like 2
chr11_+_67583742 0.25 ENST00000398603.6
glutathione S-transferase pi 1
chr1_+_247416166 0.25 ENST00000391827.3
ENST00000336119.8
NLR family pyrin domain containing 3
chr11_+_67583803 0.25 ENST00000398606.10
glutathione S-transferase pi 1
chr11_+_706196 0.25 ENST00000534755.5
ENST00000650127.1
EPS8 like 2
chr16_-_4614859 0.24 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
UBA like domain containing 1
chr5_+_136059151 0.24 ENST00000503087.1
transforming growth factor beta induced
chr11_-_47185840 0.24 ENST00000539589.5
ENST00000528462.5
protein kinase C and casein kinase substrate in neurons 3
chr3_-_98522514 0.23 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
claudin domain containing 1
chr12_-_104958268 0.23 ENST00000432951.1
ENST00000258538.8
ENST00000415674.1
ENST00000424946.1
ENST00000433540.5
solute carrier family 41 member 2
chr6_-_30717264 0.23 ENST00000376406.8
mediator of DNA damage checkpoint 1
chr1_-_6602885 0.23 ENST00000377663.3
kelch like family member 21
chr13_-_35855627 0.23 ENST00000379893.5
doublecortin like kinase 1
chr17_+_76385256 0.22 ENST00000392496.3
sphingosine kinase 1
chr1_+_26863140 0.22 ENST00000339276.6
stratifin
chr11_-_95232514 0.21 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
sestrin 3
chr1_-_6602859 0.21 ENST00000377658.8
kelch like family member 21
chr8_-_8893548 0.21 ENST00000276282.7
malignant fibrous histiocytoma amplified sequence 1
chr11_+_706595 0.20 ENST00000531348.5
ENST00000530636.5
EPS8 like 2
chr12_+_10213417 0.20 ENST00000546017.5
ENST00000535576.5
ENST00000539170.5
GABA type A receptor associated protein like 1
chr18_+_24113341 0.19 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr19_+_38899680 0.19 ENST00000576510.5
ENST00000392079.7
NFKB inhibitor beta
chr3_-_142028597 0.19 ENST00000467667.5
transcription factor Dp-2
chr1_-_23799533 0.19 ENST00000429356.5
UDP-galactose-4-epimerase
chr1_+_36155930 0.18 ENST00000316156.8
MAP7 domain containing 1
chr14_+_93997296 0.18 ENST00000636493.2
coiled-coil domain containing 197
chr1_+_36156096 0.18 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7 domain containing 1
chr11_+_18599782 0.17 ENST00000634992.1
ENST00000635674.1
ENST00000511927.2
SPTY2D1 opposite strand
chr7_-_32070396 0.17 ENST00000396191.6
phosphodiesterase 1C
chr10_-_25062279 0.17 ENST00000615958.4
enkurin, TRPC channel interacting protein
chr5_-_137736066 0.17 ENST00000309755.9
kelch like family member 3
chr20_-_17558811 0.16 ENST00000536626.7
ENST00000377868.6
beaded filament structural protein 1
chr8_-_67746348 0.16 ENST00000297770.10
carboxypeptidase A6
chr14_+_94026314 0.16 ENST00000203664.10
ENST00000553723.1
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr11_-_2171805 0.15 ENST00000381178.5
ENST00000381175.5
ENST00000333684.9
ENST00000352909.8
tyrosine hydroxylase
chr17_+_27471999 0.15 ENST00000583370.5
ENST00000509603.6
ENST00000268763.10
ENST00000398988.7
kinase suppressor of ras 1
chr1_-_23799561 0.15 ENST00000445705.1
UDP-galactose-4-epimerase
chr19_-_35528221 0.15 ENST00000588674.5
ENST00000452271.7
ENST00000518157.1
suprabasin
chr4_-_99657820 0.15 ENST00000511828.2
chromosome 4 open reading frame 54
chr12_-_118190510 0.15 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr12_-_14961610 0.15 ENST00000542276.1
Rho GDP dissociation inhibitor beta
chr6_-_43629222 0.14 ENST00000307126.10
GTP binding protein 2
chr16_+_71526419 0.14 ENST00000539698.4
carbohydrate sulfotransferase 4
chr22_+_39520553 0.14 ENST00000674920.3
ENST00000679776.1
ENST00000675582.2
ENST00000337304.2
ENST00000676346.2
ENST00000396680.3
ENST00000680446.1
ENST00000674568.2
ENST00000680748.1
ENST00000674835.2
activating transcription factor 4
chr4_-_79408198 0.14 ENST00000358842.5
glycerol kinase 2
chr22_-_32464440 0.14 ENST00000397450.2
ENST00000397452.5
ENST00000300399.8
BPI fold containing family C
chr12_-_14961256 0.14 ENST00000541380.5
Rho GDP dissociation inhibitor beta
chr6_+_47656436 0.13 ENST00000507065.5
ENST00000296862.5
adhesion G protein-coupled receptor F2
chr2_+_28392802 0.13 ENST00000379619.5
ENST00000264716.9
FOS like 2, AP-1 transcription factor subunit
chr17_-_29078857 0.13 ENST00000359450.6
TGFB1-induced anti-apoptotic factor 1
chr7_-_135728177 0.13 ENST00000682651.1
ENST00000354042.8
solute carrier family 13 member 4
chr2_-_96035974 0.13 ENST00000434632.5
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr12_-_14961559 0.13 ENST00000228945.9
ENST00000541546.5
Rho GDP dissociation inhibitor beta
chr14_-_22957100 0.13 ENST00000555367.5
HAUS augmin like complex subunit 4
chr3_-_98522869 0.13 ENST00000502288.5
ENST00000512147.5
ENST00000341181.11
ENST00000510541.5
ENST00000503621.5
ENST00000511081.5
ENST00000507874.5
ENST00000502299.5
ENST00000508659.5
ENST00000510545.5
ENST00000511667.5
ENST00000394185.6
claudin domain containing 1
chr4_-_7434895 0.13 ENST00000319098.7
prosaposin like 1
chr9_+_100429511 0.13 ENST00000613183.1
Myb/SANT DNA binding domain containing 3
chr1_-_207051202 0.13 ENST00000315927.9
YOD1 deubiquitinase
chr12_-_51009264 0.13 ENST00000545993.7
solute carrier family 11 member 2
chr8_-_27258414 0.13 ENST00000523048.5
stathmin 4
chr20_-_653189 0.12 ENST00000381962.4
sulfiredoxin 1
chr8_-_26867267 0.12 ENST00000380573.4
adrenoceptor alpha 1A
chr14_-_22957061 0.12 ENST00000557591.5
ENST00000541587.6
ENST00000490506.5
ENST00000554406.1
HAUS augmin like complex subunit 4
chr11_-_111379268 0.12 ENST00000393067.8
POU class 2 homeobox associating factor 1
chr11_-_11353241 0.12 ENST00000528848.3
casein kinase 2 alpha 3
chr11_-_124310837 0.11 ENST00000357821.2
olfactory receptor family 8 subfamily D member 1
chr8_+_26293112 0.11 ENST00000523925.5
ENST00000315985.7
protein phosphatase 2 regulatory subunit Balpha
chr14_-_22957128 0.11 ENST00000342454.12
ENST00000555986.5
ENST00000554516.5
ENST00000347758.6
ENST00000206474.11
ENST00000555040.5
HAUS augmin like complex subunit 4
chr7_+_74209989 0.11 ENST00000361082.7
ENST00000275635.11
ENST00000460943.6
ENST00000470709.1
linker for activation of T cells family member 2
chr11_-_102843597 0.11 ENST00000299855.10
matrix metallopeptidase 3
chr15_-_76012390 0.11 ENST00000394907.8
neuregulin 4
chr16_-_72172135 0.11 ENST00000537465.5
ENST00000237353.15
polyamine modulated factor 1 binding protein 1
chr11_-_64245816 0.10 ENST00000542235.1
protein phosphatase 1 regulatory inhibitor subunit 14B
chr18_-_48137295 0.10 ENST00000535628.6
zinc finger and BTB domain containing 7C
chr11_+_102112445 0.10 ENST00000524575.5
Yes1 associated transcriptional regulator
chr19_+_46601296 0.10 ENST00000598871.5
ENST00000291295.14
ENST00000594523.5
calmodulin 3
chr5_+_14664653 0.10 ENST00000284274.5
OTU deubiquitinase with linear linkage specificity
chr1_-_11848345 0.10 ENST00000376476.1
natriuretic peptide A
chr12_-_48957445 0.10 ENST00000541959.5
ENST00000447318.6
ENST00000256682.9
ADP ribosylation factor 3
chr7_+_39623547 0.10 ENST00000005257.7
RAS like proto-oncogene A
chr16_-_30113528 0.09 ENST00000406256.8
glycerophosphodiester phosphodiesterase domain containing 3
chr13_-_35855758 0.09 ENST00000615680.4
doublecortin like kinase 1
chr2_+_68974573 0.09 ENST00000673932.3
ENST00000377938.4
gastrokine 1
chr1_-_94541636 0.09 ENST00000370207.4
coagulation factor III, tissue factor
chr3_-_52835011 0.09 ENST00000446157.3
musculoskeletal, embryonic nuclear protein 1
chr8_-_142614469 0.08 ENST00000356613.4
activity regulated cytoskeleton associated protein
chr19_-_15464525 0.08 ENST00000343625.12
RAS protein activator like 3
chr1_-_11847772 0.08 ENST00000376480.7
ENST00000610706.1
natriuretic peptide A
chr17_-_41178219 0.08 ENST00000377726.3
keratin associated protein 4-2
chr17_-_18258556 0.08 ENST00000579294.5
ENST00000628188.1
ENST00000545457.6
ENST00000578558.5
ENST00000327031.9
FLII actin remodeling protein
chr1_-_118185157 0.08 ENST00000336338.10
sperm associated antigen 17
chr6_-_656963 0.08 ENST00000380907.2
HUS1 checkpoint clamp component B
chr11_-_102874974 0.08 ENST00000571244.3
matrix metallopeptidase 12
chr6_-_83709141 0.08 ENST00000521743.5
synaptosome associated protein 91
chr7_+_112423137 0.08 ENST00000005558.8
ENST00000621379.4
interferon related developmental regulator 1
chrX_-_20141810 0.07 ENST00000379593.1
ENST00000379607.10
eukaryotic translation initiation factor 1A X-linked
chr4_+_107824555 0.07 ENST00000394684.8
sphingomyelin synthase 2
chr19_-_51065067 0.07 ENST00000595547.5
ENST00000335422.3
ENST00000595793.6
ENST00000596955.1
kallikrein related peptidase 13
chr18_+_9885964 0.07 ENST00000357775.6
ENST00000306084.6
thioredoxin domain containing 2
chr3_-_31981228 0.07 ENST00000396556.7
ENST00000438237.6
oxysterol binding protein like 10
chrX_+_123960519 0.07 ENST00000455404.5
ENST00000218089.13
stromal antigen 2
chr1_-_94541746 0.07 ENST00000334047.12
coagulation factor III, tissue factor
chr2_-_11466156 0.07 ENST00000381525.8
ENST00000307236.8
ENST00000542100.5
ENST00000546212.2
E2F transcription factor 6
chr17_-_75405486 0.07 ENST00000392562.5
growth factor receptor bound protein 2
chr19_+_1407517 0.07 ENST00000336761.10
ENST00000233078.9
ENST00000592522.5
DAZ associated protein 1
chr11_-_124315099 0.07 ENST00000641897.1
olfactory receptor family 8 subfamily D member 1
chr11_-_47176851 0.07 ENST00000629231.2
ENST00000526342.5
ENST00000528444.5
ENST00000530596.5
ENST00000525398.5
ENST00000524782.6
ENST00000527927.5
ENST00000525314.5
ADP ribosylation factor GTPase activating protein 2
chr7_+_1086800 0.07 ENST00000413368.5
ENST00000397092.5
ENST00000297469.3
G protein-coupled estrogen receptor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.6 2.9 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.5 1.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.3 0.9 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.3 1.0 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.2 0.9 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.2 6.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.5 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.2 0.5 GO:0035732 nitric oxide storage(GO:0035732)
0.1 1.2 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.4 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.7 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.4 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.3 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 1.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 1.5 GO:0051546 keratinocyte migration(GO:0051546)
0.1 1.8 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.2 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.5 GO:0032621 interleukin-18 production(GO:0032621)
0.1 0.4 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.9 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 0.8 GO:0015886 heme transport(GO:0015886)
0.1 0.3 GO:0015862 uridine transport(GO:0015862)
0.1 0.6 GO:0002934 desmosome organization(GO:0002934)
0.1 0.2 GO:0052314 phthalate metabolic process(GO:0018963) epinephrine biosynthetic process(GO:0042418) phytoalexin metabolic process(GO:0052314)
0.0 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.7 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.4 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 1.1 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 1.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.2 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.4 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 1.2 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.4 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.3 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:2000724 positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.1 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 2.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.6 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.6 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.5 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 3.4 GO:0001533 cornified envelope(GO:0001533)
0.1 0.6 GO:0030057 desmosome(GO:0030057)
0.1 0.4 GO:0005827 polar microtubule(GO:0005827)
0.0 0.9 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.5 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.3 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.2 1.0 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 0.5 GO:0035730 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.9 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 1.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.8 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.6 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0031753 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 2.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 3.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.0 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.4 PID P73PATHWAY p73 transcription factor network
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 6.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants