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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for FOSL2_SMARCC1

Z-value: 1.48

Motif logo

Transcription factors associated with FOSL2_SMARCC1

Gene Symbol Gene ID Gene Info
ENSG00000075426.12 FOS like 2, AP-1 transcription factor subunit
ENSG00000173473.11 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSL2hg38_v1_chr2_+_28395511_28395743-0.363.9e-01Click!
SMARCC1hg38_v1_chr3_-_47781837_47781908-0.049.2e-01Click!

Activity profile of FOSL2_SMARCC1 motif

Sorted Z-values of FOSL2_SMARCC1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_23873000 6.29 ENST00000269217.11
ENST00000587184.5
laminin subunit alpha 3
chr19_-_35513641 2.33 ENST00000339686.8
ENST00000447113.6
dermokine
chr17_-_41612757 2.29 ENST00000301653.9
ENST00000593067.1
keratin 16
chr19_-_35501878 2.29 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
dermokine
chr20_+_46008900 1.89 ENST00000372330.3
matrix metallopeptidase 9
chr18_+_63775369 1.77 ENST00000540675.5
serpin family B member 7
chr19_-_51020154 1.75 ENST00000391805.5
ENST00000599077.1
kallikrein related peptidase 10
chr18_+_63775395 1.74 ENST00000398019.7
serpin family B member 7
chr2_+_102001966 1.69 ENST00000457817.5
interleukin 1 receptor type 2
chr19_-_51020019 1.66 ENST00000309958.7
kallikrein related peptidase 10
chr11_-_102798148 1.57 ENST00000315274.7
matrix metallopeptidase 1
chr3_-_151316795 1.51 ENST00000260843.5
G protein-coupled receptor 87
chr15_+_40239857 1.49 ENST00000260404.8
p21 (RAC1) activated kinase 6
chr7_+_73830988 1.47 ENST00000340958.4
claudin 4
chr11_+_394196 1.40 ENST00000331563.7
ENST00000531857.1
plakophilin 3
chr2_+_47369301 1.36 ENST00000263735.9
epithelial cell adhesion molecule
chr7_+_26291850 1.31 ENST00000338523.9
ENST00000446848.6
sorting nexin 10
chr6_+_130366281 1.24 ENST00000617887.4
transmembrane protein 200A
chr18_+_36544544 1.11 ENST00000591635.5
formin homology 2 domain containing 3
chr8_+_81732434 1.08 ENST00000297265.5
charged multivesicular body protein 4C
chr6_+_130365958 1.05 ENST00000296978.4
transmembrane protein 200A
chr1_+_183186238 1.02 ENST00000493293.5
ENST00000264144.5
laminin subunit gamma 2
chr12_-_52949818 1.00 ENST00000546897.5
ENST00000552551.5
keratin 8
chr11_+_10455292 0.98 ENST00000396553.6
adenosine monophosphate deaminase 3
chr6_-_138107412 0.96 ENST00000421351.4
p53 apoptosis effector related to PMP22
chr1_+_34755039 0.94 ENST00000338513.1
gap junction protein beta 5
chr1_-_12616762 0.90 ENST00000464917.5
dehydrogenase/reductase 3
chr3_+_36380477 0.89 ENST00000457375.6
ENST00000273183.8
ENST00000434649.1
SH3 and cysteine rich domain
chr19_+_38789198 0.85 ENST00000314980.5
galectin 7B
chr11_-_118264282 0.83 ENST00000278937.7
myelin protein zero like 2
chr6_+_47698574 0.80 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr18_+_63777773 0.80 ENST00000447428.5
ENST00000546027.5
serpin family B member 7
chr15_+_40239042 0.80 ENST00000558055.5
ENST00000455577.6
p21 (RAC1) activated kinase 6
chr2_-_112784486 0.80 ENST00000263339.4
interleukin 1 alpha
chr6_+_47698538 0.79 ENST00000327753.7
adhesion G protein-coupled receptor F4
chr10_+_24466487 0.79 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr15_+_40844018 0.78 ENST00000344051.8
ENST00000562057.6
serine peptidase inhibitor, Kunitz type 1
chr15_+_40239420 0.77 ENST00000560346.5
p21 (RAC1) activated kinase 6
chr19_-_43670153 0.74 ENST00000601723.5
ENST00000339082.7
ENST00000340093.8
plasminogen activator, urokinase receptor
chr16_+_57628684 0.72 ENST00000567397.5
ENST00000568979.5
ENST00000672974.1
adhesion G protein-coupled receptor G1
chr1_+_14929734 0.72 ENST00000376028.8
ENST00000400798.6
kazrin, periplakin interacting protein
chr12_-_95116967 0.71 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr1_-_153549120 0.71 ENST00000368712.1
S100 calcium binding protein A3
chr16_+_57628507 0.69 ENST00000456916.5
ENST00000567154.5
ENST00000388813.9
ENST00000562558.6
ENST00000566271.6
ENST00000563374.5
ENST00000673126.2
ENST00000562631.7
ENST00000568234.5
ENST00000565770.5
ENST00000566164.5
adhesion G protein-coupled receptor G1
chr2_+_113117889 0.69 ENST00000361779.7
ENST00000259206.9
ENST00000354115.6
interleukin 1 receptor antagonist
chr1_-_153549238 0.68 ENST00000368713.8
S100 calcium binding protein A3
chr17_+_57085092 0.68 ENST00000575322.1
ENST00000337714.8
A-kinase anchoring protein 1
chr3_-_98522514 0.68 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
claudin domain containing 1
chr11_-_118264445 0.66 ENST00000438295.2
myelin protein zero like 2
chr12_-_94616061 0.66 ENST00000551457.1
transmembrane and coiled-coil domain family 3
chr17_-_29176752 0.64 ENST00000533112.5
myosin XVIIIA
chr3_-_12759224 0.63 ENST00000314124.12
ENST00000435218.6
ENST00000435575.5
transmembrane protein 40
chr17_-_7590072 0.63 ENST00000538513.6
ENST00000570788.1
ENST00000250055.3
SRY-box transcription factor 15
chr17_+_50532713 0.62 ENST00000503690.5
ENST00000514874.5
ENST00000268933.8
epsin 3
chr6_+_41637005 0.59 ENST00000419164.6
ENST00000373051.6
MyoD family inhibitor
chr18_-_76495191 0.58 ENST00000443185.7
zinc finger protein 516
chr2_+_219627565 0.57 ENST00000273063.10
solute carrier family 4 member 3
chr17_-_8118489 0.57 ENST00000380149.6
ENST00000448843.7
arachidonate lipoxygenase 3
chr6_+_47656436 0.57 ENST00000507065.5
ENST00000296862.5
adhesion G protein-coupled receptor F2
chr13_-_85799400 0.57 ENST00000647374.2
SLIT and NTRK like family member 6
chr2_+_219627650 0.56 ENST00000317151.7
solute carrier family 4 member 3
chr1_+_2073462 0.56 ENST00000400921.6
protein kinase C zeta
chr2_+_219627622 0.56 ENST00000358055.8
solute carrier family 4 member 3
chr9_-_137054016 0.55 ENST00000312665.7
ENST00000355097.7
ectonucleoside triphosphate diphosphohydrolase 2
chr1_-_6602885 0.55 ENST00000377663.3
kelch like family member 21
chr19_-_38773432 0.53 ENST00000599035.1
ENST00000378626.5
galectin 7
chr1_+_2073986 0.53 ENST00000461106.6
protein kinase C zeta
chr1_-_6602859 0.52 ENST00000377658.8
kelch like family member 21
chr1_-_209651291 0.51 ENST00000391911.5
ENST00000415782.1
laminin subunit beta 3
chr1_-_28193873 0.51 ENST00000305392.3
ENST00000539896.1
platelet activating factor receptor
chr9_+_35673917 0.51 ENST00000617161.1
ENST00000378357.9
carbonic anhydrase 9
chr10_-_5978022 0.51 ENST00000525219.6
interleukin 15 receptor subunit alpha
chr10_-_5977589 0.50 ENST00000620345.4
ENST00000397251.7
ENST00000397248.6
ENST00000622442.4
ENST00000620865.4
interleukin 15 receptor subunit alpha
chr6_+_30884353 0.50 ENST00000428153.6
ENST00000376568.8
ENST00000452441.5
ENST00000515219.5
discoidin domain receptor tyrosine kinase 1
chr11_+_62881686 0.49 ENST00000536981.6
ENST00000539891.6
solute carrier family 3 member 2
chr1_-_156705575 0.48 ENST00000368222.8
cellular retinoic acid binding protein 2
chr10_-_5977535 0.47 ENST00000379977.8
interleukin 15 receptor subunit alpha
chr18_+_63587336 0.47 ENST00000344731.10
serpin family B member 13
chr1_-_153057504 0.47 ENST00000392653.3
small proline rich protein 2A
chr4_-_36244438 0.46 ENST00000303965.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr19_-_35528221 0.46 ENST00000588674.5
ENST00000452271.7
ENST00000518157.1
suprabasin
chr22_+_44677044 0.44 ENST00000006251.11
proline rich 5
chr6_+_106098933 0.44 ENST00000369089.3
PR/SET domain 1
chr2_-_237590660 0.44 ENST00000409576.1
RAB17, member RAS oncogene family
chr22_+_44677077 0.43 ENST00000403581.5
proline rich 5
chr16_+_30740621 0.43 ENST00000615541.3
ENST00000483578.1
transmembrane protein 265
novel transcript
chr7_-_945799 0.43 ENST00000611167.4
ArfGAP with dual PH domains 1
chr22_+_44676808 0.43 ENST00000624862.3
proline rich 5
chr17_-_41786688 0.41 ENST00000310706.9
ENST00000393931.8
ENST00000424457.5
ENST00000591690.5
junction plakoglobin
chr4_+_75556048 0.41 ENST00000616557.1
ENST00000435974.2
ENST00000311623.9
odontogenesis associated phosphoprotein
chr16_+_22297375 0.41 ENST00000615879.4
ENST00000299853.10
ENST00000564209.5
ENST00000565358.5
ENST00000418581.6
ENST00000564883.5
ENST00000359210.8
ENST00000563024.5
RNA polymerase III subunit E
chr13_+_77535669 0.40 ENST00000535157.5
sciellin
chr18_+_58196736 0.40 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr8_+_119208322 0.40 ENST00000614891.5
mal, T cell differentiation protein 2
chr17_+_32444379 0.40 ENST00000578213.5
ENST00000649012.1
ENST00000457654.6
ENST00000579451.1
ENST00000261712.8
proteasome 26S subunit, non-ATPase 11
chr11_-_75490725 0.40 ENST00000529721.5
glycerophosphodiester phosphodiesterase domain containing 5
chr17_+_75721471 0.40 ENST00000450894.7
integrin subunit beta 4
chrX_+_71910818 0.39 ENST00000633930.1
NHS like 2
chr6_+_36130484 0.39 ENST00000373766.9
ENST00000211287.9
mitogen-activated protein kinase 13
chr13_+_77535681 0.38 ENST00000349847.4
sciellin
chr6_+_44227025 0.38 ENST00000371708.1
solute carrier family 29 member 1 (Augustine blood group)
chr13_+_77535742 0.38 ENST00000377246.7
sciellin
chr2_+_232697362 0.38 ENST00000482666.5
ENST00000483164.5
ENST00000490229.5
ENST00000464805.5
ENST00000489328.1
GRB10 interacting GYF protein 2
chr14_+_96256194 0.38 ENST00000216629.11
ENST00000553356.1
bradykinin receptor B1
chrX_-_31178149 0.37 ENST00000679437.1
dystrophin
chr7_-_20217342 0.37 ENST00000400331.10
ENST00000332878.8
MET transcriptional regulator MACC1
chr2_+_17878637 0.37 ENST00000304101.9
potassium voltage-gated channel modifier subfamily S member 3
chr17_+_75721327 0.37 ENST00000579662.5
integrin subunit beta 4
chr1_-_43285559 0.36 ENST00000523677.6
chromosome 1 open reading frame 210
chr16_-_30113528 0.36 ENST00000406256.8
glycerophosphodiester phosphodiesterase domain containing 3
chr22_-_37188281 0.35 ENST00000397110.6
C1q and TNF related 6
chr12_+_56079843 0.35 ENST00000549282.5
ENST00000549061.5
ENST00000683059.1
erb-b2 receptor tyrosine kinase 3
chr9_-_23826299 0.35 ENST00000380117.5
ELAV like RNA binding protein 2
chr10_+_73911104 0.35 ENST00000446342.5
ENST00000372764.4
plasminogen activator, urokinase
chrX_-_33211540 0.35 ENST00000357033.9
dystrophin
chr2_-_237590694 0.34 ENST00000264601.8
ENST00000411462.5
ENST00000409822.1
RAB17, member RAS oncogene family
chr15_+_88638947 0.33 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr5_+_145937793 0.33 ENST00000511217.1
SH3 domain containing ring finger 2
chr12_-_8066331 0.33 ENST00000546241.1
ENST00000307637.5
complement C3a receptor 1
chr17_-_19004727 0.33 ENST00000388995.11
family with sequence similarity 83 member G
chrX_-_31178220 0.33 ENST00000681026.1
dystrophin
chrX_-_15664798 0.33 ENST00000380342.4
collectrin, amino acid transport regulator
chr19_+_7888499 0.33 ENST00000618098.4
ENST00000306708.11
ENST00000600345.1
ENST00000598224.5
leucine rich repeat containing 8 VRAC subunit E
chr1_-_153094521 0.33 ENST00000368750.8
small proline rich protein 2E
chr11_+_1834804 0.33 ENST00000341958.3
synaptotagmin 8
chr4_+_83536097 0.33 ENST00000395226.6
ENST00000264409.5
glycerol-3-phosphate acyltransferase 3
chr9_-_122228845 0.32 ENST00000394319.8
ENST00000340587.7
LIM homeobox 6
chr5_+_145936554 0.32 ENST00000359120.9
SH3 domain containing ring finger 2
chr5_+_35856883 0.32 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr2_+_86441341 0.31 ENST00000312912.10
ENST00000409064.5
lysine demethylase 3A
chrX_-_24647300 0.31 ENST00000379144.7
phosphate cytidylyltransferase 1, choline, beta
chr12_+_56080155 0.31 ENST00000267101.8
erb-b2 receptor tyrosine kinase 3
chr19_-_50969567 0.31 ENST00000310157.7
kallikrein related peptidase 6
chr17_+_80101562 0.30 ENST00000302262.8
ENST00000577106.5
ENST00000390015.7
alpha glucosidase
chr19_-_35490456 0.30 ENST00000338897.4
ENST00000484218.6
keratinocyte differentiation associated protein
chr15_+_88639009 0.30 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr17_-_41140487 0.29 ENST00000345847.4
keratin associated protein 4-6
chr11_+_1834415 0.29 ENST00000381968.7
ENST00000381978.7
synaptotagmin 8
chr6_-_30744537 0.29 ENST00000259874.6
ENST00000376377.2
immediate early response 3
chr8_+_123768431 0.29 ENST00000334705.12
ENST00000521166.5
family with sequence similarity 91 member A1
chr17_+_21288029 0.28 ENST00000526076.6
ENST00000361818.9
ENST00000316920.10
mitogen-activated protein kinase kinase 3
chr2_+_89851723 0.28 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr10_+_102395693 0.28 ENST00000652277.1
ENST00000189444.11
ENST00000661543.1
nuclear factor kappa B subunit 2
chr15_-_44194407 0.28 ENST00000484674.5
FERM domain containing 5
chr6_+_150721073 0.28 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chrX_-_24647091 0.28 ENST00000356768.8
phosphate cytidylyltransferase 1, choline, beta
chr11_+_35176575 0.28 ENST00000526000.6
CD44 molecule (Indian blood group)
chr3_-_122793772 0.27 ENST00000306103.3
HSPB1 associated protein 1
chr6_+_32153441 0.27 ENST00000414204.5
ENST00000361568.6
ENST00000395523.5
palmitoyl-protein thioesterase 2
chrX_-_155334580 0.27 ENST00000369449.7
ENST00000321926.4
chloride intracellular channel 2
chr17_-_41586887 0.26 ENST00000167586.7
keratin 14
chr5_+_150640652 0.26 ENST00000307662.5
synaptopodin
chr2_-_64144411 0.26 ENST00000358912.5
pellino E3 ubiquitin protein ligase 1
chr12_+_56338873 0.26 ENST00000228534.6
interleukin 23 subunit alpha
chr12_-_104958268 0.26 ENST00000432951.1
ENST00000258538.8
ENST00000415674.1
ENST00000424946.1
ENST00000433540.5
solute carrier family 41 member 2
chr4_+_107824555 0.25 ENST00000394684.8
sphingomyelin synthase 2
chr16_+_50266530 0.25 ENST00000566433.6
ENST00000394697.7
ENST00000673801.1
adenylate cyclase 7
chr11_+_66975295 0.25 ENST00000683896.1
chromosome 11 open reading frame 86
chr5_+_136059151 0.25 ENST00000503087.1
transforming growth factor beta induced
chr11_+_66975271 0.25 ENST00000308963.4
chromosome 11 open reading frame 86
chr11_+_128694052 0.25 ENST00000527786.7
ENST00000534087.3
Fli-1 proto-oncogene, ETS transcription factor
chr11_+_59755427 0.25 ENST00000529177.5
syntaxin 3
chr11_+_128693887 0.24 ENST00000281428.12
Fli-1 proto-oncogene, ETS transcription factor
chr7_+_48088596 0.24 ENST00000416681.5
ENST00000331803.8
ENST00000432131.5
uridine phosphorylase 1
chr5_-_79514127 0.24 ENST00000334082.11
homer scaffold protein 1
chr1_-_9910169 0.24 ENST00000377263.6
catenin beta interacting protein 1
chr10_-_5977492 0.24 ENST00000530685.5
ENST00000397255.7
ENST00000379971.5
ENST00000528354.5
ENST00000397250.6
ENST00000429135.2
interleukin 15 receptor subunit alpha
chr6_-_30717264 0.24 ENST00000376406.8
mediator of DNA damage checkpoint 1
chr2_+_119431846 0.23 ENST00000306406.5
transmembrane protein 37
chr19_+_9185594 0.23 ENST00000344248.4
olfactory receptor family 7 subfamily D member 2
chr18_-_77127935 0.23 ENST00000581878.5
myelin basic protein
chr20_-_1329131 0.23 ENST00000360779.4
syndecan binding protein 2
chr17_-_31314040 0.23 ENST00000330927.5
ecotropic viral integration site 2B
chr2_+_90021567 0.23 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr22_-_37188233 0.22 ENST00000434784.1
ENST00000337843.7
C1q and TNF related 6
chr10_-_127892930 0.22 ENST00000368671.4
clarin 3
chr1_+_26863140 0.22 ENST00000339276.6
stratifin
chr12_-_94650506 0.22 ENST00000261226.9
transmembrane and coiled-coil domain family 3
chr11_+_68312542 0.22 ENST00000294304.12
LDL receptor related protein 5
chr6_-_35921047 0.21 ENST00000361690.7
ENST00000512445.5
SRSF protein kinase 1
chr1_+_36156096 0.21 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7 domain containing 1
chr12_+_8992029 0.21 ENST00000543895.1
killer cell lectin like receptor G1
chr5_+_141637398 0.21 ENST00000518856.1
RELT like 2
chr20_+_37383648 0.21 ENST00000373567.6
SRC proto-oncogene, non-receptor tyrosine kinase
chr6_+_31114793 0.20 ENST00000259881.10
psoriasis susceptibility 1 candidate 1
chr12_-_10674013 0.20 ENST00000535345.5
ENST00000542562.5
ENST00000075503.8
serine/threonine/tyrosine kinase 1
chr6_-_35921079 0.20 ENST00000507909.1
ENST00000373825.7
SRSF protein kinase 1
chr17_+_37491464 0.20 ENST00000613659.1
dual specificity phosphatase 14
chr1_+_36155930 0.20 ENST00000316156.8
MAP7 domain containing 1
chr6_-_35921128 0.20 ENST00000510290.5
ENST00000423325.6
SRSF protein kinase 1
chr16_-_72172135 0.19 ENST00000537465.5
ENST00000237353.15
polyamine modulated factor 1 binding protein 1
chr13_-_35855627 0.19 ENST00000379893.5
doublecortin like kinase 1
chr10_-_49269 0.19 ENST00000562809.1
ENST00000568866.5
ENST00000561967.1
ENST00000568584.6
tubulin beta 8 class VIII
chr2_+_90069662 0.19 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr5_-_135578983 0.19 ENST00000512158.6
C-X-C motif chemokine ligand 14
chr11_+_59755365 0.19 ENST00000337979.9
syntaxin 3
chr19_-_55370455 0.19 ENST00000264563.7
ENST00000585513.1
ENST00000590625.5
interleukin 11
chr4_-_170026333 0.19 ENST00000504999.1
microfibril associated protein 3 like
chr5_+_136058849 0.18 ENST00000508076.5
transforming growth factor beta induced
chrX_-_120311533 0.18 ENST00000440464.5
ENST00000519908.1
transmembrane protein 255A

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL2_SMARCC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:1903575 cornified envelope assembly(GO:1903575)
0.9 4.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.5 1.8 GO:0002159 desmosome assembly(GO:0002159)
0.4 1.7 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.3 2.6 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.3 8.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 0.8 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 0.9 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 1.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.2 0.6 GO:1903028 positive regulation of opsonization(GO:1903028)
0.2 0.6 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.2 1.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 1.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 1.0 GO:0006196 AMP catabolic process(GO:0006196)
0.2 1.0 GO:0002934 desmosome organization(GO:0002934)
0.2 0.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.6 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.4 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.1 4.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.6 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 0.3 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.5 GO:1902943 regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943)
0.1 0.3 GO:0002086 diaphragm contraction(GO:0002086)
0.1 0.8 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.3 GO:0035732 nitric oxide storage(GO:0035732)
0.1 1.3 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.5 GO:0060356 leucine import(GO:0060356)
0.1 0.2 GO:0046108 uridine metabolic process(GO:0046108)
0.1 1.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.1 1.0 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 1.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.3 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.2 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.2 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.6 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.2 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.6 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.5 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.3 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1 0.4 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.6 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.6 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 1.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:2001286 cellular response to progesterone stimulus(GO:0071393) regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.5 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 2.5 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 0.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.5 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.0 0.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 1.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.4 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.2 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 0.4 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.3 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.3 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.0 0.1 GO:1901090 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.0 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.0 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.0 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.4 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097) positive regulation of autophagosome maturation(GO:1901098)
0.0 0.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.1 GO:0060681 positive regulation of cholesterol biosynthetic process(GO:0045542) branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.0 GO:0014806 smooth muscle hyperplasia(GO:0014806)
0.0 0.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.0 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:1902031 NADP biosynthetic process(GO:0006741) regulation of NADP metabolic process(GO:1902031)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.8 GO:0005610 laminin-5 complex(GO:0005610)
0.2 1.0 GO:0043256 laminin complex(GO:0043256)
0.2 1.4 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 1.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.1 GO:0005827 polar microtubule(GO:0005827)
0.1 0.5 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 3.5 GO:0030057 desmosome(GO:0030057)
0.1 1.1 GO:0045179 apical cortex(GO:0045179)
0.1 0.2 GO:0097444 spine apparatus(GO:0097444)
0.1 1.1 GO:0016013 syntrophin complex(GO:0016013)
0.1 2.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 0.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 1.1 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.8 GO:0001533 cornified envelope(GO:0001533)
0.1 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 1.3 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0019031 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 1.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.0 GO:0034515 proteasome storage granule(GO:0034515)
0.0 2.6 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 0.7 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.2 0.6 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.4 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.6 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.1 1.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0035730 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
0.1 2.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 2.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.3 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.1 0.2 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.1 1.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.2 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.4 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 1.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 1.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.0 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 5.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.5 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 2.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.6 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.2 GO:0042835 BRE binding(GO:0042835)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 4.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.6 GO:0043531 ADP binding(GO:0043531)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 4.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.1 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.1 PID NECTIN PATHWAY Nectin adhesion pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 9.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 1.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 2.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids