Project

avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

Navigation
Downloads

Results for GATA1_GATA4

Z-value: 0.27

Motif logo

Transcription factors associated with GATA1_GATA4

Gene Symbol Gene ID Gene Info
ENSG00000102145.15 GATA binding protein 1
ENSG00000136574.19 GATA binding protein 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA4hg38_v1_chr8_+_11704151_11704242,
hg38_v1_chr8_+_11676952_11676966
0.334.2e-01Click!
GATA1hg38_v1_chrX_+_48786578_487865970.304.6e-01Click!

Activity profile of GATA1_GATA4 motif

Sorted Z-values of GATA1_GATA4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_22169580 1.00 ENST00000269216.10
GATA binding protein 6
chr10_-_127892930 0.68 ENST00000368671.4
clarin 3
chr8_+_123182635 0.45 ENST00000276699.10
ENST00000522648.5
family with sequence similarity 83 member A
chr3_+_148865288 0.40 ENST00000296046.4
carboxypeptidase A3
chr19_-_51019699 0.39 ENST00000358789.8
kallikrein related peptidase 10
chr2_+_196639686 0.37 ENST00000389175.9
coiled-coil domain containing 150
chr1_-_24143112 0.32 ENST00000270800.2
interleukin 22 receptor subunit alpha 1
chr6_+_12290353 0.32 ENST00000379375.6
endothelin 1
chr8_-_15238423 0.32 ENST00000382080.6
sarcoglycan zeta
chr11_-_116837586 0.32 ENST00000375320.5
ENST00000359492.6
ENST00000375329.6
ENST00000375323.5
ENST00000236850.5
apolipoprotein A1
chr4_-_102345196 0.30 ENST00000683412.1
ENST00000682227.1
solute carrier family 39 member 8
chr1_-_201399525 0.29 ENST00000367313.4
ladinin 1
chr6_+_1389553 0.29 ENST00000645481.2
forkhead box F2
chr12_+_56083308 0.28 ENST00000683164.1
ENST00000415288.6
ENST00000683018.1
erb-b2 receptor tyrosine kinase 3
chr19_+_35248994 0.28 ENST00000427250.5
ENST00000605618.6
lipolysis stimulated lipoprotein receptor
chr1_-_225999312 0.28 ENST00000272091.8
SDE2 telomere maintenance homolog
chr1_-_201399302 0.28 ENST00000633953.1
ENST00000391967.7
ladinin 1
chr19_+_35248879 0.27 ENST00000347609.8
lipolysis stimulated lipoprotein receptor
chr11_+_34621065 0.26 ENST00000257831.8
ETS homologous factor
chr1_-_209652329 0.26 ENST00000367030.7
ENST00000356082.9
laminin subunit beta 3
chrX_-_79367307 0.25 ENST00000373298.7
integral membrane protein 2A
chr1_+_154321076 0.25 ENST00000324978.8
aquaporin 10
chr5_+_132073782 0.24 ENST00000296871.4
colony stimulating factor 2
chr5_+_36608146 0.24 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr1_-_175192911 0.24 ENST00000444639.5
KIAA0040
chr1_+_34782259 0.23 ENST00000373362.3
gap junction protein beta 3
chrX_+_44844015 0.22 ENST00000339042.6
dual specificity phosphatase 21
chr9_+_87726086 0.22 ENST00000677821.1
ENST00000677019.1
ENST00000678649.1
ENST00000342020.6
ENST00000677262.1
ENST00000343150.10
ENST00000677864.1
ENST00000340342.11
ENST00000676881.1
ENST00000676769.1
ENST00000678596.1
ENST00000679030.1
ENST00000678599.1
ENST00000677761.1
cathepsin L
chr20_+_45306834 0.22 ENST00000343694.8
ENST00000372741.7
ENST00000372743.5
recombination signal binding protein for immunoglobulin kappa J region like
chr16_-_81220370 0.22 ENST00000337114.8
polycystin 1 like 2 (gene/pseudogene)
chrX_+_47078380 0.21 ENST00000352078.8
regucalcin
chrX_+_47078434 0.21 ENST00000397180.6
regucalcin
chr11_+_34621109 0.21 ENST00000450654.6
ETS homologous factor
chr1_+_206865620 0.21 ENST00000367098.6
interleukin 20
chr3_-_98593589 0.21 ENST00000647941.2
coproporphyrinogen oxidase
chr1_+_154321107 0.20 ENST00000484864.1
aquaporin 10
chr1_+_202203721 0.20 ENST00000255432.11
leucine rich repeat containing G protein-coupled receptor 6
chr6_-_11778781 0.20 ENST00000414691.8
ENST00000229583.9
androgen dependent TFPI regulating protein
chr11_-_124441158 0.20 ENST00000328064.2
olfactory receptor family 8 subfamily B member 8
chr1_-_93585071 0.20 ENST00000539242.5
BCAR3 adaptor protein, NSP family member
chr19_-_12887188 0.20 ENST00000264834.6
Kruppel like factor 1
chr17_+_76385256 0.20 ENST00000392496.3
sphingosine kinase 1
chr8_-_20183090 0.20 ENST00000265808.11
ENST00000522513.5
solute carrier family 18 member A1
chr1_-_225427897 0.20 ENST00000421383.1
ENST00000272163.9
lamin B receptor
chr14_+_64214136 0.19 ENST00000557084.1
ENST00000458046.6
spectrin repeat containing nuclear envelope protein 2
chr12_-_120327762 0.19 ENST00000308366.9
ENST00000423423.3
phospholipase A2 group IB
chr2_+_147845020 0.19 ENST00000241416.12
activin A receptor type 2A
chr8_-_20183127 0.18 ENST00000276373.10
ENST00000519026.5
ENST00000440926.3
ENST00000437980.3
solute carrier family 18 member A1
chr15_-_43220989 0.18 ENST00000540029.5
ENST00000441366.7
ENST00000648595.1
erythrocyte membrane protein band 4.2
chr3_-_119660580 0.18 ENST00000493094.6
ENST00000264231.7
ENST00000468801.1
popeye domain containing 2
chr1_+_25272492 0.18 ENST00000454452.6
Rh blood group D antigen
chr5_+_67004618 0.17 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr2_+_188291854 0.17 ENST00000409830.6
GULP PTB domain containing engulfment adaptor 1
chr7_+_150852507 0.17 ENST00000416793.6
ENST00000360937.9
ENST00000483043.1
amine oxidase copper containing 1
chr6_+_29306626 0.17 ENST00000377160.4
olfactory receptor family 14 subfamily J member 1
chr13_-_46182136 0.17 ENST00000323076.7
lymphocyte cytosolic protein 1
chr2_+_102311502 0.16 ENST00000404917.6
ENST00000410040.5
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr19_-_50983815 0.16 ENST00000391807.5
ENST00000593904.1
ENST00000595820.6
kallikrein related peptidase 7
chr12_+_8992029 0.16 ENST00000543895.1
killer cell lectin like receptor G1
chr18_+_63777773 0.16 ENST00000447428.5
ENST00000546027.5
serpin family B member 7
chr8_+_32721823 0.16 ENST00000539990.3
ENST00000519240.5
neuregulin 1
chr5_+_140841183 0.16 ENST00000378123.4
ENST00000531613.2
protocadherin alpha 8
chr11_-_125778788 0.16 ENST00000436890.2
prostate and testis expressed 2
chr6_+_137871208 0.15 ENST00000614035.4
ENST00000621150.3
ENST00000619035.4
ENST00000615468.4
ENST00000620204.3
TNF alpha induced protein 3
chr1_+_200027605 0.15 ENST00000236914.7
nuclear receptor subfamily 5 group A member 2
chr1_-_177164673 0.15 ENST00000424564.2
ENST00000361833.7
astrotactin 1
chrX_+_152914426 0.15 ENST00000318504.11
ENST00000449285.6
ENST00000539731.5
ENST00000535861.5
ENST00000370268.8
ENST00000370270.6
zinc finger protein 185 with LIM domain
chr1_-_43367689 0.15 ENST00000621943.4
ELOVL fatty acid elongase 1
chrX_+_38352573 0.15 ENST00000039007.5
ornithine transcarbamylase
chr2_+_188291661 0.15 ENST00000409843.5
GULP PTB domain containing engulfment adaptor 1
chr4_-_102345061 0.15 ENST00000394833.6
solute carrier family 39 member 8
chr12_-_70637405 0.15 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
protein tyrosine phosphatase receptor type B
chr12_+_8950036 0.14 ENST00000539240.5
killer cell lectin like receptor G1
chr10_+_88664439 0.14 ENST00000394375.7
ENST00000608620.5
ENST00000238983.9
ENST00000355843.2
lipase F, gastric type
chr1_-_99766620 0.14 ENST00000646001.2
ferric chelate reductase 1
chr9_-_112175185 0.14 ENST00000355396.7
sushi domain containing 1
chr6_+_125219804 0.14 ENST00000524679.1
TPD52 like 1
chrX_+_48521788 0.14 ENST00000651615.1
ENST00000495186.6
novel protein
EBP cholestenol delta-isomerase
chr4_-_71784046 0.14 ENST00000513476.5
ENST00000273951.13
GC vitamin D binding protein
chr11_-_59845496 0.14 ENST00000257248.3
cobalamin binding intrinsic factor
chr15_-_51738095 0.14 ENST00000560491.2
LysM domain containing 2
chr15_+_78340344 0.14 ENST00000299529.7
cellular retinoic acid binding protein 1
chr19_-_13102848 0.14 ENST00000264824.5
LYL1 basic helix-loop-helix family member
chr12_-_70754631 0.14 ENST00000440835.6
ENST00000549308.5
ENST00000550661.1
ENST00000378778.5
protein tyrosine phosphatase receptor type R
chr6_+_30647008 0.14 ENST00000293604.10
ENST00000376473.9
chromosome 6 open reading frame 136
chr2_+_188291911 0.14 ENST00000410051.5
GULP PTB domain containing engulfment adaptor 1
chr1_+_81306096 0.13 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
adhesion G protein-coupled receptor L2
chr16_+_69105636 0.13 ENST00000569188.6
hyaluronan synthase 3
chr15_-_34336749 0.13 ENST00000397707.6
ENST00000560611.5
solute carrier family 12 member 6
chr11_-_1036706 0.13 ENST00000421673.7
mucin 6, oligomeric mucus/gel-forming
chr6_-_170291053 0.13 ENST00000366756.4
delta like canonical Notch ligand 1
chr10_+_80413817 0.13 ENST00000372187.9
peroxiredoxin like 2A
chr19_-_35501878 0.13 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
dermokine
chr17_-_31314040 0.13 ENST00000330927.5
ecotropic viral integration site 2B
chr10_-_94362925 0.13 ENST00000371361.3
NOC3 like DNA replication regulator
chr6_+_30647109 0.13 ENST00000651131.1
ENST00000376471.8
chromosome 6 open reading frame 136
chr17_-_41124178 0.13 ENST00000394014.2
keratin associated protein 4-12
chr7_-_20217342 0.12 ENST00000400331.10
ENST00000332878.8
MET transcriptional regulator MACC1
chr2_-_40512361 0.12 ENST00000403092.5
solute carrier family 8 member A1
chr4_+_153466324 0.12 ENST00000409663.7
ENST00000409959.8
transmembrane 131 like
chr3_+_189789643 0.12 ENST00000354600.10
tumor protein p63
chr7_-_142962206 0.12 ENST00000460479.2
ENST00000476829.5
ENST00000355265.7
Kell metallo-endopeptidase (Kell blood group)
chr15_-_34318761 0.12 ENST00000290209.9
solute carrier family 12 member 6
chr15_-_78944985 0.11 ENST00000615999.5
ENST00000677789.1
ENST00000676880.1
ENST00000677936.1
ENST00000220166.10
ENST00000677810.1
ENST00000678644.1
ENST00000677534.1
ENST00000677316.1
cathepsin H
chr19_+_10286944 0.11 ENST00000380770.5
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr12_+_53268289 0.11 ENST00000257934.9
extra spindle pole bodies like 1, separase
chr1_+_14929734 0.11 ENST00000376028.8
ENST00000400798.6
kazrin, periplakin interacting protein
chr19_+_10286971 0.11 ENST00000340992.4
ENST00000393717.2
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr19_-_50984028 0.11 ENST00000597707.5
kallikrein related peptidase 7
chr13_-_31162341 0.11 ENST00000445273.6
ENST00000630972.2
heat shock protein family H (Hsp110) member 1
chrX_-_15664798 0.11 ENST00000380342.4
collectrin, amino acid transport regulator
chr19_+_15640880 0.11 ENST00000586182.6
ENST00000221307.13
ENST00000591058.5
cytochrome P450 family 4 subfamily F member 3
chr1_-_32817311 0.11 ENST00000373477.9
ENST00000675785.1
tyrosyl-tRNA synthetase 1
chr6_+_130018565 0.11 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chrX_+_108044967 0.11 ENST00000415430.7
V-set and immunoglobulin domain containing 1
chr1_+_40988513 0.11 ENST00000649215.1
CTP synthase 1
chr8_-_90082871 0.11 ENST00000265431.7
calbindin 1
chr15_-_43879835 0.11 ENST00000636859.1
FERM domain containing 5
chr9_-_6565462 0.10 ENST00000638661.1
ENST00000640208.1
glycine decarboxylase
chr15_+_40844018 0.10 ENST00000344051.8
ENST00000562057.6
serine peptidase inhibitor, Kunitz type 1
chr16_+_71526419 0.10 ENST00000539698.4
carbohydrate sulfotransferase 4
chrX_-_24647300 0.10 ENST00000379144.7
phosphate cytidylyltransferase 1, choline, beta
chr10_+_116591010 0.10 ENST00000530319.5
ENST00000527980.5
ENST00000471549.5
ENST00000534537.5
pancreatic lipase related protein 1
chr2_+_32165841 0.10 ENST00000357055.7
ENST00000435660.5
ENST00000440718.5
ENST00000379343.6
ENST00000282587.9
ENST00000406369.2
solute carrier family 30 member 6
chr1_-_246931892 0.10 ENST00000648844.2
AT-hook containing transcription factor 1
chr1_-_225428813 0.10 ENST00000338179.6
ENST00000425080.1
lamin B receptor
chr1_+_86993009 0.10 ENST00000370548.3
novel protein
chrX_+_108045050 0.10 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr14_-_22815421 0.10 ENST00000674313.1
ENST00000555959.1
solute carrier family 7 member 7
chr5_+_51383394 0.10 ENST00000230658.12
ISL LIM homeobox 1
chr3_-_79767987 0.10 ENST00000464233.6
roundabout guidance receptor 1
chr4_+_48986268 0.10 ENST00000226432.9
cell wall biogenesis 43 C-terminal homolog
chr2_-_40512423 0.10 ENST00000402441.5
ENST00000448531.1
solute carrier family 8 member A1
chr12_+_103965863 0.10 ENST00000392872.8
ENST00000537100.5
thymine DNA glycosylase
chrX_+_135309480 0.10 ENST00000635820.1
embryonic testis differentiation homolog C
chr9_-_112175283 0.09 ENST00000374270.8
ENST00000374263.7
sushi domain containing 1
chr10_+_116590956 0.09 ENST00000358834.9
ENST00000528052.5
pancreatic lipase related protein 1
chr14_+_22497657 0.09 ENST00000390496.1
T cell receptor alpha joining 41
chr14_-_22815801 0.09 ENST00000397532.9
solute carrier family 7 member 7
chr17_-_49764123 0.09 ENST00000240364.7
ENST00000506156.1
family with sequence similarity 117 member A
chr1_-_111503622 0.09 ENST00000369716.9
ENST00000241356.5
transmembrane and immunoglobulin domain containing 3
adenosine A3 receptor
chrX_+_129779930 0.09 ENST00000356892.4
SAM and SH3 domain containing 3
chr2_+_188291994 0.09 ENST00000409927.5
ENST00000409805.5
GULP PTB domain containing engulfment adaptor 1
chr6_-_47042306 0.09 ENST00000371253.7
adhesion G protein-coupled receptor F1
chr6_+_47698574 0.09 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr14_+_85530163 0.09 ENST00000554746.1
fibronectin leucine rich transmembrane protein 2
chr3_+_169911566 0.09 ENST00000428432.6
ENST00000335556.7
sterile alpha motif domain containing 7
chr14_-_22815856 0.09 ENST00000554758.1
ENST00000397528.8
solute carrier family 7 member 7
chr12_+_12070932 0.09 ENST00000308721.9
BCL2 like 14
chr6_+_47698538 0.09 ENST00000327753.7
adhesion G protein-coupled receptor F4
chrX_+_48521817 0.09 ENST00000446158.5
ENST00000414061.1
EBP cholestenol delta-isomerase
chr7_-_99784175 0.09 ENST00000651514.1
ENST00000336411.7
ENST00000415003.1
ENST00000354593.6
cytochrome P450 family 3 subfamily A member 4
chr11_-_125778818 0.09 ENST00000358524.8
prostate and testis expressed 2
chr12_-_9999176 0.09 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chr8_+_27771942 0.09 ENST00000523566.5
establishment of sister chromatid cohesion N-acetyltransferase 2
chr19_+_54724479 0.09 ENST00000291860.1
ENST00000400864.3
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3
novel transcript
chr4_-_112636858 0.09 ENST00000503172.5
ENST00000505019.6
ENST00000309071.9
zinc finger GRF-type containing 1
chr10_-_102837406 0.09 ENST00000369887.4
ENST00000638272.1
ENST00000639393.1
ENST00000638971.1
ENST00000638190.1
cytochrome P450 family 17 subfamily A member 1
chr12_-_21775581 0.08 ENST00000537950.1
ENST00000665145.1
potassium inwardly rectifying channel subfamily J member 8
chr20_-_5010284 0.08 ENST00000379333.5
solute carrier family 23 member 2
chr13_-_46142834 0.08 ENST00000674665.1
lymphocyte cytosolic protein 1
chr9_-_124507382 0.08 ENST00000373588.9
ENST00000620110.4
nuclear receptor subfamily 5 group A member 1
chr14_+_21042352 0.08 ENST00000298690.5
ribonuclease A family member 7
chr1_+_174877430 0.08 ENST00000392064.6
RAB GTPase activating protein 1 like
chr3_-_151278535 0.08 ENST00000309170.8
purinergic receptor P2Y14
chr17_-_75844334 0.08 ENST00000592386.5
ENST00000412096.6
ENST00000586147.1
ENST00000207549.9
unc-13 homolog D
chr14_+_85530127 0.08 ENST00000330753.6
fibronectin leucine rich transmembrane protein 2
chr5_+_151437040 0.08 ENST00000520111.5
ENST00000520701.5
ENST00000429484.6
solute carrier family 36 member 1
chr18_+_44700796 0.08 ENST00000677130.1
SET binding protein 1
chr3_-_155676363 0.08 ENST00000494598.5
phospholipase C eta 1
chr11_+_118359572 0.08 ENST00000252108.8
ENST00000431736.6
ubiquitination factor E4A
chr11_-_75096876 0.08 ENST00000641541.1
ENST00000641593.1
ENST00000641504.1
ENST00000641931.1
ENST00000647690.1
olfactory receptor family 2 subfamily AT member 4
novel transcript
chr20_-_290364 0.08 ENST00000382369.9
chromosome 20 open reading frame 96
chr17_-_66229380 0.08 ENST00000205948.11
apolipoprotein H
chr7_+_123655857 0.08 ENST00000458573.3
ENST00000456238.2
leiomodin 2
chr11_+_10305065 0.08 ENST00000534464.1
ENST00000278175.10
ENST00000530439.1
ENST00000524948.5
ENST00000528655.5
ENST00000526492.4
ENST00000525063.2
adrenomedullin
chr21_+_33543031 0.08 ENST00000356577.10
ENST00000381692.6
ENST00000300278.8
ENST00000381679.8
SON DNA and RNA binding protein
chr5_+_148063971 0.07 ENST00000398454.5
ENST00000359874.7
ENST00000508733.5
ENST00000256084.8
serine peptidase inhibitor Kazal type 5
chr22_+_21420636 0.07 ENST00000407598.2
HIC ZBTB transcriptional repressor 2
chr7_+_117014881 0.07 ENST00000422922.5
ENST00000432298.5
suppression of tumorigenicity 7
chr3_+_172750715 0.07 ENST00000392692.8
ENST00000417960.5
ENST00000428567.5
ENST00000366090.6
ENST00000426894.5
epithelial cell transforming 2
chrX_-_24672654 0.07 ENST00000379145.5
phosphate cytidylyltransferase 1, choline, beta
chr11_+_60699605 0.07 ENST00000300226.7
membrane spanning 4-domains A8
chr18_+_58221535 0.07 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr2_+_173354820 0.07 ENST00000347703.7
ENST00000410101.7
ENST00000410019.3
ENST00000306721.8
cell division cycle associated 7
chr14_+_22271921 0.07 ENST00000390464.2
T cell receptor alpha variable 38-1
chr7_-_99735093 0.07 ENST00000611620.4
ENST00000620220.6
ENST00000336374.4
CYP3A7-CYP3A51P readthrough
cytochrome P450 family 3 subfamily A member 7
chr6_-_46921926 0.07 ENST00000283296.12
adhesion G protein-coupled receptor F5
chr4_-_64409444 0.07 ENST00000381210.8
ENST00000507440.5
trans-2,3-enoyl-CoA reductase like
chr2_+_105744876 0.07 ENST00000233154.9
ENST00000451463.6
NCK adaptor protein 2
chr11_-_5324297 0.07 ENST00000624187.1
olfactory receptor family 51 subfamily B member 2
chr1_+_12464912 0.07 ENST00000543766.2
vacuolar protein sorting 13 homolog D
chr17_+_19411220 0.07 ENST00000461366.2
ring finger protein 112
chr2_-_162071183 0.07 ENST00000678668.1
dipeptidyl peptidase 4
chr12_-_52553139 0.07 ENST00000267119.6
keratin 71
chr17_+_7650916 0.07 ENST00000250111.9
ATPase Na+/K+ transporting subunit beta 2
chr7_-_44141074 0.07 ENST00000457314.5
ENST00000447951.1
ENST00000431007.1
myosin light chain 7
chr22_-_29388530 0.07 ENST00000357586.7
ENST00000432560.6
ENST00000405198.6
ENST00000317368.11
adaptor related protein complex 1 subunit beta 1
chr15_+_74541200 0.07 ENST00000622429.1
ENST00000346246.10
AT-rich interaction domain 3B
chr1_-_167518521 0.07 ENST00000362089.10
CD247 molecule

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA1_GATA4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.1 0.3 GO:0030185 nitric oxide transport(GO:0030185)
0.1 0.4 GO:1903610 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.1 0.6 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.2 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.3 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.1 0.4 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.5 GO:0015793 glycerol transport(GO:0015793)
0.1 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.2 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.1 0.2 GO:1990523 bone regeneration(GO:1990523)
0.1 0.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.3 GO:0002786 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.2 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.4 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.3 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.3 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.2 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.0 0.2 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0061580 colon epithelial cell migration(GO:0061580)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0060913 visceral motor neuron differentiation(GO:0021524) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.0 0.0 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.0 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.1 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0 0.1 GO:0070904 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0018963 phthalate metabolic process(GO:0018963)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.1 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.2 GO:0017085 response to insecticide(GO:0017085)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0036100 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.0 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.0 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.4 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.0 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) negative regulation of energy homeostasis(GO:2000506)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0060125 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.0 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.3 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.0 GO:0036269 swimming behavior(GO:0036269)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.2 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.0 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.6 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.3 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.0 GO:0097545 radial spoke(GO:0001534) axonemal outer doublet(GO:0097545)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004341 gluconolactonase activity(GO:0004341)
0.1 0.3 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.4 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.2 GO:0047750 C-8 sterol isomerase activity(GO:0000247) cholestenol delta-isomerase activity(GO:0047750)
0.1 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:1902271 D3 vitamins binding(GO:1902271)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.1 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.2 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.1 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.0 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.0 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.0 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor