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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for GATA2

Z-value: 3.21

Motif logo

Transcription factors associated with GATA2

Gene Symbol Gene ID Gene Info
ENSG00000179348.12 GATA binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA2hg38_v1_chr3_-_128493173_128493208-0.705.2e-02Click!

Activity profile of GATA2 motif

Sorted Z-values of GATA2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91153149 5.09 ENST00000550758.1
decorin
chr12_-_91179355 3.78 ENST00000550563.5
ENST00000546370.5
decorin
chr1_+_78490966 3.40 ENST00000370757.8
ENST00000370756.3
prostaglandin F receptor
chr12_-_91179472 3.40 ENST00000550099.5
ENST00000546391.5
decorin
chr13_+_101489940 3.08 ENST00000376162.7
integrin subunit beta like 1
chr14_-_91946989 2.88 ENST00000556154.5
fibulin 5
chr3_+_157436842 2.54 ENST00000295927.4
pentraxin 3
chr1_+_113979460 2.53 ENST00000320334.5
olfactomedin like 3
chr12_-_91146195 2.38 ENST00000548218.1
decorin
chr5_-_20575850 2.36 ENST00000507958.5
cadherin 18
chr5_-_76623391 2.32 ENST00000296641.5
ENST00000504899.1
coagulation factor II thrombin receptor like 2
chr1_+_113979391 2.30 ENST00000393300.6
ENST00000369551.5
olfactomedin like 3
chr12_-_91180365 2.14 ENST00000547937.5
decorin
chr1_+_183805105 2.13 ENST00000360851.4
ral guanine nucleotide dissociation stimulator like 1
chr10_+_68106109 1.90 ENST00000540630.5
ENST00000354393.6
myopalladin
chr12_-_91178520 1.84 ENST00000425043.5
ENST00000420120.6
ENST00000441303.6
ENST00000456569.2
decorin
chr20_+_36214373 1.76 ENST00000432603.1
erythrocyte membrane protein band 4.1 like 1
chr1_+_180196536 1.63 ENST00000443059.1
quiescin sulfhydryl oxidase 1
chr9_+_96928310 1.62 ENST00000354649.7
NUT family member 2G
chr5_-_19988179 1.61 ENST00000502796.5
ENST00000382275.6
ENST00000511273.1
cadherin 18
chr2_-_201697993 1.60 ENST00000428900.6
membrane palmitoylated protein 4
chr13_+_75804221 1.54 ENST00000489941.6
ENST00000525373.5
LIM domain 7
chr17_-_50201618 1.45 ENST00000225964.10
collagen type I alpha 1 chain
chr9_-_92424427 1.39 ENST00000375550.5
osteomodulin
chr1_+_201780490 1.36 ENST00000430015.5
neuron navigator 1
chr13_-_33205997 1.31 ENST00000399365.7
StAR related lipid transfer domain containing 13
chr10_+_69088096 1.29 ENST00000242465.4
serglycin
chr18_-_27990256 1.28 ENST00000675173.1
cadherin 2
chr9_+_87497222 1.26 ENST00000358077.9
death associated protein kinase 1
chr1_-_72100930 1.18 ENST00000306821.3
neuronal growth regulator 1
chr10_-_77140757 1.18 ENST00000637862.2
potassium calcium-activated channel subfamily M alpha 1
chr4_+_125314918 1.18 ENST00000674496.2
ENST00000394329.9
FAT atypical cadherin 4
chr16_+_55479188 1.17 ENST00000219070.9
matrix metallopeptidase 2
chr9_-_76692181 1.17 ENST00000376717.6
ENST00000223609.10
prune homolog 2 with BCH domain
chr5_+_149141573 1.15 ENST00000506113.5
actin binding LIM protein family member 3
chr2_-_224982420 1.14 ENST00000645028.1
dedicator of cytokinesis 10
chr1_+_77918128 1.14 ENST00000342754.5
nexilin F-actin binding protein
chr9_-_111036207 1.07 ENST00000541779.5
lysophosphatidic acid receptor 1
chr11_-_118679637 1.06 ENST00000264029.9
ENST00000397925.2
trehalase
chr6_+_101181254 1.02 ENST00000682090.1
ENST00000421544.6
glutamate ionotropic receptor kainate type subunit 2
chr6_-_87095059 1.02 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr2_-_79086847 0.99 ENST00000454188.5
regenerating family member 1 beta
chr1_-_168729187 0.98 ENST00000367817.4
dermatopontin
chr19_+_14440254 0.95 ENST00000342216.8
protein kinase N1
chr6_-_154430495 0.95 ENST00000424998.3
CNKSR family member 3
chr13_+_23570370 0.94 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr7_-_38631356 0.92 ENST00000356264.7
ENST00000325590.9
amphiphysin
chr4_-_56681588 0.92 ENST00000554144.5
ENST00000381260.7
HOP homeobox
chr2_-_201698040 0.91 ENST00000396886.7
ENST00000409143.5
membrane palmitoylated protein 4
chr8_-_92095627 0.90 ENST00000517919.5
ENST00000617740.4
ENST00000613302.4
ENST00000436581.6
ENST00000614812.4
ENST00000519847.5
RUNX1 partner transcriptional co-repressor 1
chr18_-_28177934 0.86 ENST00000676445.1
cadherin 2
chr13_+_75804169 0.86 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr12_+_1629197 0.85 ENST00000397196.7
Wnt family member 5B
chr2_-_213151590 0.84 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chr19_+_15949008 0.83 ENST00000322107.1
olfactory receptor family 10 subfamily H member 4
chr12_-_123972824 0.83 ENST00000238156.8
ENST00000545037.1
coiled-coil domain containing 92
chr8_-_92017292 0.81 ENST00000521553.5
RUNX1 partner transcriptional co-repressor 1
chr16_+_15434475 0.81 ENST00000566490.5
bMERB domain containing 1
chr8_-_23854796 0.78 ENST00000290271.7
stanniocalcin 1
chr3_+_141386393 0.76 ENST00000503809.5
zinc finger and BTB domain containing 38
chr20_+_13008919 0.76 ENST00000399002.7
ENST00000434210.5
serine palmitoyltransferase long chain base subunit 3
chr19_+_54816468 0.76 ENST00000391728.8
ENST00000326542.11
ENST00000358178.4
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
chr2_+_200440649 0.76 ENST00000366118.2
spermatogenesis associated serine rich 2 like
chr3_+_155080307 0.75 ENST00000360490.7
membrane metalloendopeptidase
chr9_-_20382461 0.75 ENST00000380321.5
ENST00000629733.3
MLLT3 super elongation complex subunit
chr11_-_96343170 0.75 ENST00000524717.6
mastermind like transcriptional coactivator 2
chr3_+_148697784 0.74 ENST00000497524.5
ENST00000418473.7
ENST00000349243.8
ENST00000404754.2
angiotensin II receptor type 1
chr8_-_92017637 0.74 ENST00000422361.6
RUNX1 partner transcriptional co-repressor 1
chr2_+_201129826 0.73 ENST00000457277.5
CASP8 and FADD like apoptosis regulator
chr15_-_93073706 0.73 ENST00000425933.6
repulsive guidance molecule BMP co-receptor a
chr11_+_111976902 0.72 ENST00000614104.4
DIX domain containing 1
chr6_+_72212887 0.72 ENST00000523963.5
regulating synaptic membrane exocytosis 1
chr3_+_141324208 0.72 ENST00000509842.5
zinc finger and BTB domain containing 38
chr12_-_55688891 0.71 ENST00000557555.2
integrin subunit alpha 7
chr8_-_13514744 0.70 ENST00000316609.9
DLC1 Rho GTPase activating protein
chr3_-_66500973 0.68 ENST00000383703.3
ENST00000273261.8
leucine rich repeats and immunoglobulin like domains 1
chr5_+_68292562 0.68 ENST00000523872.1
phosphoinositide-3-kinase regulatory subunit 1
chr3_+_155083889 0.68 ENST00000680282.1
membrane metalloendopeptidase
chr3_+_155083523 0.68 ENST00000680057.1
membrane metalloendopeptidase
chr16_+_15434577 0.67 ENST00000300006.9
bMERB domain containing 1
chr6_+_72212802 0.67 ENST00000401910.7
regulating synaptic membrane exocytosis 1
chr2_-_174846405 0.67 ENST00000409597.5
ENST00000413882.6
chimerin 1
chr7_+_134745460 0.67 ENST00000436461.6
caldesmon 1
chr3_-_197949869 0.67 ENST00000452735.1
ENST00000453254.5
ENST00000455191.5
IQ motif containing G
chr12_+_59664677 0.67 ENST00000548610.5
solute carrier family 16 member 7
chr8_-_27611424 0.66 ENST00000405140.7
clusterin
chr7_-_23347704 0.66 ENST00000619562.4
insulin like growth factor 2 mRNA binding protein 3
chr3_+_155080088 0.66 ENST00000462745.5
membrane metalloendopeptidase
chr22_-_28306645 0.64 ENST00000612946.4
tetratricopeptide repeat domain 28
chr5_-_160685379 0.64 ENST00000642502.1
ATPase phospholipid transporting 10B (putative)
chr15_+_76336755 0.64 ENST00000290759.9
ISL LIM homeobox 2
chrX_+_10158448 0.63 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr14_+_21070273 0.61 ENST00000555038.5
ENST00000298694.9
Rho guanine nucleotide exchange factor 40
chr12_+_65279445 0.61 ENST00000642404.1
methionine sulfoxide reductase B3
chr5_-_38595396 0.61 ENST00000263409.8
LIF receptor subunit alpha
chr15_-_93073111 0.61 ENST00000557420.1
ENST00000542321.6
repulsive guidance molecule BMP co-receptor a
chr17_-_50767505 0.61 ENST00000450727.6
ANKRD40 C-terminal like
chr1_-_46665849 0.60 ENST00000532925.5
ENST00000542495.5
ATP synthase mitochondrial F1 complex assembly factor 1
chr12_-_76559672 0.59 ENST00000549570.5
oxysterol binding protein like 8
chr13_+_31846713 0.59 ENST00000645780.1
FRY microtubule binding protein
chr8_+_76681208 0.58 ENST00000651372.2
zinc finger homeobox 4
chr12_+_79045625 0.58 ENST00000552744.5
synaptotagmin 1
chr14_-_106088573 0.58 ENST00000632099.1
immunoglobulin heavy variable 3-64D
chr11_+_124739927 0.57 ENST00000284292.11
ENST00000412681.2
neurogranin
chr13_+_93226787 0.57 ENST00000377047.9
glypican 6
chr9_-_92482350 0.57 ENST00000375543.2
asporin
chr8_+_69492793 0.56 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
sulfatase 1
chr3_-_49132994 0.56 ENST00000305544.9
ENST00000494831.1
ENST00000418109.5
laminin subunit beta 2
chr14_+_60981114 0.56 ENST00000354886.6
solute carrier family 38 member 6
chr4_+_159241016 0.55 ENST00000644902.1
Rap guanine nucleotide exchange factor 2
chr2_+_209579399 0.55 ENST00000360351.8
microtubule associated protein 2
chr1_-_83999097 0.55 ENST00000260505.13
ENST00000610996.1
tubulin tyrosine ligase like 7
chr1_-_79006680 0.54 ENST00000370742.4
ENST00000656841.1
adhesion G protein-coupled receptor L4
chr3_-_179259208 0.54 ENST00000485523.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr8_-_130386864 0.54 ENST00000521426.5
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr3_+_29280945 0.52 ENST00000434693.6
RNA binding motif single stranded interacting protein 3
chr11_+_20022550 0.52 ENST00000533917.5
neuron navigator 2
chr8_-_27611325 0.52 ENST00000523500.5
clusterin
chr10_-_88952763 0.52 ENST00000224784.10
actin alpha 2, smooth muscle
chr12_-_89526253 0.52 ENST00000547474.1
POC1B-GALNT4 readthrough
chr15_-_63157464 0.51 ENST00000330964.10
ENST00000635699.1
ENST00000439025.1
ribosomal protein S27 like
chr20_-_41300066 0.51 ENST00000436099.6
ENST00000309060.7
ENST00000373261.5
ENST00000436440.6
ENST00000560364.5
ENST00000560361.5
zinc fingers and homeoboxes 3
chr20_+_36091409 0.51 ENST00000202028.9
erythrocyte membrane protein band 4.1 like 1
chr19_-_43880142 0.51 ENST00000324394.7
zinc finger protein 404
chr7_+_134843884 0.51 ENST00000445569.6
caldesmon 1
chr11_-_82997477 0.51 ENST00000534301.5
RAB30, member RAS oncogene family
chr19_+_32675835 0.50 ENST00000334176.4
regulator of G protein signaling 9 binding protein
chr14_+_20688756 0.49 ENST00000397990.5
ENST00000555597.1
angiogenin
ribonuclease A family member 4
chr3_+_111674654 0.49 ENST00000636933.1
ENST00000393934.7
ENST00000477665.2
phosphatidylinositol specific phospholipase C X domain containing 2
chr17_-_8799365 0.49 ENST00000329805.6
major facilitator superfamily domain containing 6 like
chr1_-_163202835 0.49 ENST00000527988.1
ENST00000531476.1
ENST00000530507.5
ENST00000313961.10
regulator of G protein signaling 5
chr5_+_141370236 0.48 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr2_+_201129318 0.47 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr14_-_106005574 0.47 ENST00000390595.3
immunoglobulin heavy variable 1-3
chr2_+_61905646 0.47 ENST00000311832.5
copper metabolism domain containing 1
chr9_-_13175824 0.47 ENST00000545857.5
multiple PDZ domain crumbs cell polarity complex component
chr12_+_75480745 0.47 ENST00000266659.8
GLI pathogenesis related 1
chr12_-_52553139 0.47 ENST00000267119.6
keratin 71
chr14_+_105474781 0.47 ENST00000550577.5
ENST00000538259.2
ENST00000329146.9
cysteine rich protein 2
chr1_-_182400660 0.47 ENST00000367565.2
transmembrane epididymal protein 1
chr9_-_92482499 0.46 ENST00000375544.7
asporin
chr20_-_18497218 0.46 ENST00000337227.9
RB binding protein 9, serine hydrolase
chr22_-_18611919 0.46 ENST00000619918.1
RIMS binding protein 3
chr17_+_4950147 0.46 ENST00000522301.5
enolase 3
chr12_+_75480800 0.45 ENST00000456650.7
GLI pathogenesis related 1
chr3_-_179251615 0.45 ENST00000314235.9
ENST00000392685.6
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr5_+_141223332 0.45 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
protocadherin beta 14
novel protein
chr7_+_100119607 0.45 ENST00000262932.5
canopy FGF signaling regulator 4
chr3_+_48465811 0.45 ENST00000433541.1
ENST00000444177.1
three prime repair exonuclease 1
chr1_-_167090370 0.45 ENST00000367868.4
glycoprotein A33
chr12_-_76423256 0.44 ENST00000546946.5
oxysterol binding protein like 8
chr15_+_63189554 0.44 ENST00000559006.1
ENST00000321437.9
RAB8B, member RAS oncogene family
chr11_-_33717409 0.44 ENST00000651485.1
CD59 molecule (CD59 blood group)
chr11_-_67356970 0.44 ENST00000532830.5
DNA polymerase delta 4, accessory subunit
chr2_+_201132769 0.44 ENST00000494258.5
CASP8 and FADD like apoptosis regulator
chr14_+_105486867 0.44 ENST00000409393.6
ENST00000392531.4
cysteine rich protein 1
chr9_+_37667997 0.44 ENST00000539465.5
FERM and PDZ domain containing 1
chr11_-_59866478 0.44 ENST00000257264.4
transcobalamin 1
chr4_+_61202142 0.44 ENST00000514591.5
adhesion G protein-coupled receptor L3
chr3_-_73624840 0.44 ENST00000308537.4
ENST00000263666.9
PDZ domain containing ring finger 3
chr22_-_30470577 0.44 ENST00000435069.1
ENST00000540910.5
SEC14 like lipid binding 3
chr19_+_41003946 0.43 ENST00000593831.1
cytochrome P450 family 2 subfamily B member 6
chr6_+_52362088 0.43 ENST00000635984.1
ENST00000635760.1
ENST00000442253.3
EF-hand domain containing 1
progestin and adipoQ receptor family member 8
chr3_+_172754457 0.43 ENST00000441497.6
epithelial cell transforming 2
chr6_-_31684040 0.43 ENST00000375863.7
lymphocyte antigen 6 family member G5C
chr7_+_130293134 0.43 ENST00000445470.6
ENST00000492072.5
ENST00000222482.10
ENST00000473956.5
ENST00000493259.5
ENST00000486598.1
carboxypeptidase A4
chr2_-_40512361 0.43 ENST00000403092.5
solute carrier family 8 member A1
chr3_+_143119749 0.43 ENST00000309575.5
carbohydrate sulfotransferase 2
chr15_+_53978201 0.43 ENST00000647821.1
unc-13 homolog C
chr8_-_92103217 0.42 ENST00000615601.4
ENST00000523629.5
RUNX1 partner transcriptional co-repressor 1
chr19_-_14057573 0.42 ENST00000589048.2
paralemmin 3
chr11_+_65027402 0.42 ENST00000377244.8
ENST00000534637.5
ENST00000524831.5
sorting nexin 15
chr3_-_48717166 0.42 ENST00000413654.5
ENST00000454335.5
ENST00000440424.5
ENST00000449610.5
ENST00000443964.1
ENST00000417896.1
ENST00000413298.5
ENST00000449563.5
ENST00000443853.5
ENST00000437427.5
ENST00000446860.5
ENST00000412850.5
ENST00000424035.1
ENST00000340879.8
ENST00000431721.6
ENST00000434860.1
ENST00000328631.10
ENST00000432678.6
inositol hexakisphosphate kinase 2
chr9_+_122510802 0.42 ENST00000335302.5
olfactory receptor family 1 subfamily J member 2
chr2_+_201132928 0.42 ENST00000462763.5
CASP8 and FADD like apoptosis regulator
chrX_-_77634229 0.42 ENST00000675732.1
ATRX chromatin remodeler
chr5_-_88883199 0.41 ENST00000514015.5
ENST00000503075.1
myocyte enhancer factor 2C
chr5_+_173056345 0.40 ENST00000522692.5
ENST00000296953.6
ENST00000520420.5
CREB3 regulatory factor
chr13_-_95644690 0.40 ENST00000361396.6
ENST00000376829.7
DAZ interacting zinc finger protein 1
chr2_-_168913277 0.40 ENST00000451987.5
SPC25 component of NDC80 kinetochore complex
chr15_+_53978410 0.40 ENST00000260323.16
unc-13 homolog C
chr1_-_150808251 0.40 ENST00000271651.8
ENST00000676970.1
ENST00000679260.1
ENST00000676751.1
ENST00000677887.1
cathepsin K
chr7_-_13989891 0.40 ENST00000405218.6
ETS variant transcription factor 1
chr6_+_30557287 0.40 ENST00000376560.8
proline rich 3
chr9_+_128160217 0.39 ENST00000372994.2
chromosome 9 open reading frame 16
chr5_+_179559692 0.39 ENST00000437570.6
ENST00000393438.6
RUN and FYVE domain containing 1
chr11_-_6419394 0.39 ENST00000311051.7
amyloid beta precursor protein binding family B member 1
chr2_+_201132872 0.39 ENST00000470178.6
CASP8 and FADD like apoptosis regulator
chr11_-_122116215 0.39 ENST00000560104.2
BH3-like motif containing, cell death inducer
chrX_+_154542194 0.39 ENST00000618670.4
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chr12_-_10849464 0.38 ENST00000544994.5
ENST00000228811.8
ENST00000540107.2
proline rich 4
chr20_-_41300116 0.38 ENST00000432768.6
zinc fingers and homeoboxes 3
chr19_+_15107369 0.38 ENST00000342784.7
ENST00000597977.5
ENST00000600440.5
synapse defective Rho GTPase homolog 1
chr20_-_34872817 0.38 ENST00000427420.1
ENST00000336431.10
gamma-glutamyltransferase 7
chr14_+_88005128 0.38 ENST00000267549.5
G protein-coupled receptor 65
chr19_-_8896090 0.37 ENST00000599436.1
mucin 16, cell surface associated
chr7_-_99971845 0.37 ENST00000419575.1
alpha-2-glycoprotein 1, zinc-binding
chr16_-_2210833 0.37 ENST00000562360.5
ENST00000328540.8
ENST00000566018.1
BRICHOS domain containing 5
chr2_+_44275473 0.37 ENST00000260649.11
solute carrier family 3 member 1
chr22_+_22375984 0.37 ENST00000390296.2
immunoglobulin lambda variable 5-45

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 18.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.8 2.5 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.5 1.5 GO:0044691 tooth eruption(GO:0044691)
0.4 1.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.3 3.0 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.3 1.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.3 3.1 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.3 2.8 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 2.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.0 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.2 2.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.2 1.2 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 1.6 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 1.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 1.1 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 0.6 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.2 0.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.6 GO:0072248 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.2 0.7 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.2 0.7 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 1.0 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 0.7 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.2 1.9 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.6 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.4 GO:0099404 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.1 2.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.4 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 1.0 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.6 GO:2000670 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.4 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.3 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.1 0.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.4 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.1 0.3 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.5 GO:0090131 glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.1 0.6 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.4 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.3 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.1 1.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.4 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.4 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.5 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.5 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.8 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.4 GO:1900127 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1 0.3 GO:2000283 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.4 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.1 0.5 GO:0021564 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.1 0.3 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.1 0.6 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.1 0.3 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.2 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.4 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.2 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 1.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.6 GO:0015811 L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.1 0.4 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.1 0.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 1.8 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.4 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 1.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 1.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.5 GO:0032431 diacylglycerol biosynthetic process(GO:0006651) positive regulation of phospholipase A2 activity(GO:0032430) activation of phospholipase A2 activity(GO:0032431)
0.1 0.4 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 1.0 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 1.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.3 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.3 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.4 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 0.7 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 3.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.2 GO:0018032 protein amidation(GO:0018032)
0.1 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.5 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.2 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.4 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.1 0.8 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.9 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.6 GO:0044557 relaxation of smooth muscle(GO:0044557)
0.0 0.9 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.9 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.2 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.9 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.2 GO:1903294 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.0 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 1.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.4 GO:0097646 vascular smooth muscle cell development(GO:0097084) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.8 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0051944 positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.4 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.7 GO:1900103 NFAT protein import into nucleus(GO:0051531) positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 2.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:1903365 regulation of fear response(GO:1903365) regulation of behavioral fear response(GO:2000822)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.0 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:0014848 urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848) positive regulation of sensory perception of pain(GO:1904058)
0.0 0.1 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.4 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.4 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.2 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 1.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.2 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.2 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.5 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 1.0 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052) pentose catabolic process(GO:0019323)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 1.0 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.5 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.2 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 0.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.4 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.3 GO:0035886 vascular smooth muscle cell differentiation(GO:0035886)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.0 0.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042)
0.0 0.9 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 3.4 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.3 GO:0007220 Notch receptor processing(GO:0007220)
0.0 1.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.1 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.7 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 1.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.8 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.1 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 0.2 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.6 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.4 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.3 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.3 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:2000404 regulation of T cell migration(GO:2000404)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.3 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0 0.3 GO:0032528 microvillus organization(GO:0032528)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 1.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0044241 lipid digestion(GO:0044241)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.2 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.4 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.4 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.0 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 18.6 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 2.9 GO:0071953 elastic fiber(GO:0071953)
0.2 0.6 GO:0043260 laminin-11 complex(GO:0043260)
0.2 0.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 3.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.8 GO:0044305 calyx of Held(GO:0044305)
0.1 0.6 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.4 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 1.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 2.1 GO:0016342 catenin complex(GO:0016342)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.1 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.2 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.5 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.8 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.2 GO:0030478 actin cap(GO:0030478)
0.1 1.2 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.4 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.8 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.3 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 0.6 GO:0036128 CatSper complex(GO:0036128)
0.1 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.4 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 4.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.5 GO:0070852 cell body fiber(GO:0070852)
0.1 0.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.4 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 1.1 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 1.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.4 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.2 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.4 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.6 GO:0043218 compact myelin(GO:0043218)
0.0 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 1.0 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0032044 DSIF complex(GO:0032044)
0.0 1.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0051286 cell tip(GO:0051286)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 3.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 1.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 2.3 GO:0005901 caveola(GO:0005901)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.4 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 3.0 GO:0044309 neuron spine(GO:0044309)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 3.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 1.4 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.7 GO:0008305 integrin complex(GO:0008305)
0.0 2.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.0 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 2.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.6 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.4 2.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 1.0 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 2.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 1.6 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.3 0.3 GO:0070052 collagen V binding(GO:0070052)
0.2 0.7 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.2 1.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 2.1 GO:0001849 complement component C1q binding(GO:0001849)
0.2 0.7 GO:0046577 long-chain-alcohol oxidase activity(GO:0046577)
0.2 18.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 0.6 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 0.8 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 0.8 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.1 0.4 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 1.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 3.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.3 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.1 1.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 2.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.3 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.5 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1 0.5 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.3 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.3 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 1.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.3 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.6 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.3 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.2 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
0.1 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 1.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.5 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.6 GO:0004630 phospholipase D activity(GO:0004630)
0.1 1.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.4 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.2 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.4 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0047315 kynurenine-glyoxylate transaminase activity(GO:0047315)
0.0 0.4 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.8 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 1.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.4 GO:0030911 TPR domain binding(GO:0030911)
0.0 1.1 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.6 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 1.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 1.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.5 GO:0008320 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 2.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0032407 MutSalpha complex binding(GO:0032407)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.0 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.9 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 22.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 2.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 2.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 2.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 2.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 18.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 3.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 6.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 3.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 1.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 2.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 2.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 3.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism