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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for GLIS2

Z-value: 0.91

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Transcription factors associated with GLIS2

Gene Symbol Gene ID Gene Info
GLIS2
ENSG00000126603.9 GLIS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS2hg38_v1_chr16_+_4316052_4316075-0.186.6e-01Click!

Activity profile of GLIS2 motif

Sorted Z-values of GLIS2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_34782259 0.76 ENST00000373362.3
GJB3
gap junction protein beta 3
chr20_+_46008900 0.58 ENST00000372330.3
MMP9
matrix metallopeptidase 9
chr19_-_6720641 0.49 ENST00000245907.11
C3
complement C3
chr16_-_68236069 0.45 ENST00000473183.7
ENST00000565858.5
ESRP2
epithelial splicing regulatory protein 2
chr13_-_20192928 0.44 ENST00000382848.5
GJB2
gap junction protein beta 2
chr1_-_28193873 0.43 ENST00000305392.3
ENST00000539896.1
PTAFR
platelet activating factor receptor
chr9_-_137054016 0.42 ENST00000312665.7
ENST00000355097.7
ENTPD2
ectonucleoside triphosphate diphosphohydrolase 2
chr18_+_11752041 0.39 ENST00000423027.8
GNAL
G protein subunit alpha L
chr5_+_69492767 0.36 ENST00000681041.1
ENST00000680098.1
ENST00000680784.1
ENST00000396442.7
ENST00000681895.1
OCLN
occludin
chr2_+_219627622 0.35 ENST00000358055.8
SLC4A3
solute carrier family 4 member 3
chr1_-_156705742 0.33 ENST00000368221.1
CRABP2
cellular retinoic acid binding protein 2
chr5_-_177409535 0.33 ENST00000253496.4
F12
coagulation factor XII
chr2_+_219627650 0.33 ENST00000317151.7
SLC4A3
solute carrier family 4 member 3
chr1_-_6490564 0.31 ENST00000377725.5
ENST00000340850.10
PLEKHG5
pleckstrin homology and RhoGEF domain containing G5
chr1_-_156705764 0.31 ENST00000621784.4
ENST00000368220.1
CRABP2
cellular retinoic acid binding protein 2
chr1_-_186680411 0.31 ENST00000367468.10
PTGS2
prostaglandin-endoperoxide synthase 2
chr8_+_97869040 0.30 ENST00000254898.7
ENST00000524308.5
ENST00000522025.6
MATN2
matrilin 2
chr1_-_156705575 0.29 ENST00000368222.8
CRABP2
cellular retinoic acid binding protein 2
chr8_-_22133356 0.28 ENST00000680789.1
HR
HR lysine demethylase and nuclear receptor corepressor
chr19_+_44905785 0.28 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
APOE
apolipoprotein E
chr5_-_1523900 0.26 ENST00000283415.4
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr16_+_30183595 0.26 ENST00000219150.10
ENST00000570045.5
ENST00000565497.5
ENST00000570244.5
CORO1A
coronin 1A
chr22_+_44677077 0.26 ENST00000403581.5
PRR5
proline rich 5
chr22_+_44677044 0.26 ENST00000006251.11
PRR5
proline rich 5
chr14_+_94174284 0.26 ENST00000304338.8
PPP4R4
protein phosphatase 4 regulatory subunit 4
chr22_+_44676808 0.26 ENST00000624862.3
PRR5
proline rich 5
chr1_+_65147514 0.25 ENST00000545314.5
AK4
adenylate kinase 4
chr19_+_17747698 0.25 ENST00000594202.5
ENST00000252771.11
FCHO1
FCH and mu domain containing endocytic adaptor 1
chr22_-_39244969 0.25 ENST00000331163.11
PDGFB
platelet derived growth factor subunit B
chr18_+_79964629 0.24 ENST00000451882.3
HSBP1L1
heat shock factor binding protein 1 like 1
chr19_+_17747737 0.23 ENST00000600676.5
ENST00000600209.5
ENST00000596309.5
ENST00000598539.5
ENST00000597474.5
ENST00000593385.5
ENST00000598067.5
ENST00000593833.5
FCHO1
FCH and mu domain containing endocytic adaptor 1
chr11_-_72642450 0.23 ENST00000444035.6
ENST00000544570.5
PDE2A
phosphodiesterase 2A
chr19_+_49388243 0.23 ENST00000447857.8
KASH5
KASH domain containing 5
chr11_-_72642407 0.22 ENST00000376450.7
PDE2A
phosphodiesterase 2A
chr10_+_110226805 0.22 ENST00000651495.1
ENST00000652506.1
ENST00000651811.1
ENST00000651167.1
ENST00000651516.1
ENST00000651467.1
ENST00000651004.1
ENST00000650843.1
ENST00000650644.1
ENST00000650696.1
ENST00000652604.1
ENST00000652463.1
ENST00000650810.1
ENST00000650952.1
ENST00000652028.1
ENST00000651866.1
ENST00000651848.1
ENST00000442296.5
ENST00000369612.1
MXI1
MAX interactor 1, dimerization protein
chr22_+_29073112 0.22 ENST00000327813.9
ENST00000407188.5
KREMEN1
kringle containing transmembrane protein 1
chr1_-_231040218 0.22 ENST00000366654.5
FAM89A
family with sequence similarity 89 member A
chr13_-_113364085 0.20 ENST00000375431.9
GRTP1
growth hormone regulated TBC protein 1
chr12_+_3491189 0.20 ENST00000382622.4
PRMT8
protein arginine methyltransferase 8
chr22_+_50674879 0.20 ENST00000262795.6
SHANK3
SH3 and multiple ankyrin repeat domains 3
chrX_+_103215072 0.20 ENST00000372695.6
ENST00000372691.3
BEX4
brain expressed X-linked 4
chr1_+_47067212 0.19 ENST00000334194.4
CYP4Z1
cytochrome P450 family 4 subfamily Z member 1
chr19_-_42255119 0.18 ENST00000222329.9
ENST00000594664.1
ERF
ENSG00000268643.2
ETS2 repressor factor
novel protein
chr19_+_8052335 0.18 ENST00000680507.1
ENST00000680450.1
ENST00000681526.1
ENST00000680506.1
CCL25
C-C motif chemokine ligand 25
chr2_+_233195433 0.18 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase D
chr11_+_121576760 0.18 ENST00000532694.5
ENST00000534286.5
SORL1
sortilin related receptor 1
chr19_+_8052315 0.17 ENST00000680646.1
CCL25
C-C motif chemokine ligand 25
chr17_+_50426242 0.16 ENST00000502667.5
ACSF2
acyl-CoA synthetase family member 2
chr17_+_50426210 0.16 ENST00000506582.5
ENST00000504392.5
ENST00000300441.9
ENST00000427954.6
ACSF2
acyl-CoA synthetase family member 2
chr19_+_44914247 0.16 ENST00000588750.5
ENST00000588802.5
APOC1
apolipoprotein C1
chr19_+_44914588 0.16 ENST00000592535.6
APOC1
apolipoprotein C1
chr19_+_2249317 0.16 ENST00000221496.5
AMH
anti-Mullerian hormone
chr3_+_119173564 0.16 ENST00000264234.8
ENST00000479520.5
ENST00000494855.5
UPK1B
uroplakin 1B
chr16_-_29899043 0.15 ENST00000346932.9
ENST00000350527.7
ENST00000568380.1
SEZ6L2
seizure related 6 homolog like 2
chr12_-_109833373 0.15 ENST00000261740.7
TRPV4
transient receptor potential cation channel subfamily V member 4
chr21_+_33403391 0.14 ENST00000290219.11
ENST00000381995.5
IFNGR2
interferon gamma receptor 2
chr22_+_29073024 0.14 ENST00000400335.9
KREMEN1
kringle containing transmembrane protein 1
chr11_+_68684534 0.14 ENST00000265643.4
GAL
galanin and GMAP prepropeptide
chr17_-_35930767 0.14 ENST00000619262.4
ENST00000620284.5
RDM1
RAD52 motif containing 1
chr1_+_202203721 0.14 ENST00000255432.11
LGR6
leucine rich repeat containing G protein-coupled receptor 6
chr19_+_50476496 0.13 ENST00000597426.1
ENST00000376918.7
ENST00000334976.11
ENST00000598585.1
EMC10
ER membrane protein complex subunit 10
chr12_+_7155867 0.13 ENST00000535313.2
ENST00000331148.5
CLSTN3
calsyntenin 3
chr11_-_76206407 0.13 ENST00000621122.1
ENST00000322563.8
WNT11
Wnt family member 11
chr6_+_33080445 0.13 ENST00000428835.5
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr17_-_35930727 0.12 ENST00000616596.4
ENST00000612980.4
ENST00000613308.4
ENST00000619876.4
RDM1
RAD52 motif containing 1
chr17_+_66835110 0.12 ENST00000533854.6
CACNG5
calcium voltage-gated channel auxiliary subunit gamma 5
chr17_-_4560564 0.12 ENST00000574584.1
ENST00000381550.8
ENST00000301395.7
GGT6
gamma-glutamyltransferase 6
chr6_+_89894469 0.12 ENST00000369352.1
ENST00000638915.1
GJA10
gap junction protein alpha 10
chr9_+_136952256 0.12 ENST00000371633.8
LCN12
lipocalin 12
chr19_-_50476725 0.12 ENST00000595790.5
FAM71E1
family with sequence similarity 71 member E1
chr3_+_119173515 0.12 ENST00000497685.5
UPK1B
uroplakin 1B
chr19_+_44914833 0.11 ENST00000589078.1
ENST00000586638.5
APOC1
apolipoprotein C1
chr19_+_44914702 0.11 ENST00000592885.5
ENST00000589781.1
APOC1
apolipoprotein C1
chr19_-_45902594 0.11 ENST00000322217.6
MYPOP
Myb related transcription factor, partner of profilin
chr6_-_2903300 0.11 ENST00000380698.5
SERPINB9
serpin family B member 9
chr16_-_29899245 0.11 ENST00000537485.5
SEZ6L2
seizure related 6 homolog like 2
chr16_+_85908988 0.11 ENST00000566369.1
IRF8
interferon regulatory factor 8
chr9_+_124869126 0.11 ENST00000259477.6
ARPC5L
actin related protein 2/3 complex subunit 5 like
chr1_-_155978144 0.10 ENST00000313695.11
ENST00000497907.5
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2
chr12_+_50057548 0.10 ENST00000228468.8
ENST00000447966.7
ASIC1
acid sensing ion channel subunit 1
chr10_-_14838561 0.10 ENST00000378442.5
CDNF
cerebral dopamine neurotrophic factor
chr2_+_37344594 0.10 ENST00000404976.5
ENST00000338415.8
QPCT
glutaminyl-peptide cyclotransferase
chr15_-_79090760 0.10 ENST00000419573.7
ENST00000558480.7
RASGRF1
Ras protein specific guanine nucleotide releasing factor 1
chr21_+_33229883 0.09 ENST00000382264.7
ENST00000342136.9
ENST00000404220.7
IFNAR2
interferon alpha and beta receptor subunit 2
chr1_+_53062052 0.09 ENST00000395871.7
ENST00000673702.1
ENST00000673956.1
ENST00000312553.10
ENST00000371500.8
ENST00000618387.1
PODN
podocan
chr19_-_37906646 0.09 ENST00000303868.5
WDR87
WD repeat domain 87
chr16_+_715092 0.09 ENST00000568223.7
METRN
meteorin, glial cell differentiation regulator
chr19_+_14529580 0.09 ENST00000215567.10
TECR
trans-2,3-enoyl-CoA reductase
chr13_-_113364141 0.09 ENST00000620217.4
ENST00000375430.8
GRTP1
growth hormone regulated TBC protein 1
chr17_+_43398984 0.09 ENST00000320033.5
ARL4D
ADP ribosylation factor like GTPase 4D
chr21_+_33403466 0.09 ENST00000405436.5
IFNGR2
interferon gamma receptor 2
chr17_+_82458174 0.09 ENST00000579198.5
ENST00000390006.8
ENST00000580296.5
NARF
nuclear prelamin A recognition factor
chr19_-_15898057 0.09 ENST00000011989.11
ENST00000221700.11
CYP4F2
cytochrome P450 family 4 subfamily F member 2
chr6_-_116765709 0.09 ENST00000368557.6
FAM162B
family with sequence similarity 162 member B
chr19_+_44846175 0.09 ENST00000252485.8
ENST00000252483.10
NECTIN2
nectin cell adhesion molecule 2
chr20_+_37346128 0.09 ENST00000373578.7
SRC
SRC proto-oncogene, non-receptor tyrosine kinase
chrX_-_8732116 0.09 ENST00000262648.8
ANOS1
anosmin 1
chr19_-_50476838 0.08 ENST00000600100.6
FAM71E1
family with sequence similarity 71 member E1
chr12_-_48716675 0.08 ENST00000261900.8
ENST00000640148.1
CCNT1
cyclin T1
chr1_-_153375591 0.08 ENST00000368737.5
S100A12
S100 calcium binding protein A12
chr2_-_230068905 0.08 ENST00000457406.5
ENST00000295190.9
SLC16A14
solute carrier family 16 member 14
chrX_-_103064164 0.08 ENST00000372728.4
BEX1
brain expressed X-linked 1
chr9_+_136952896 0.08 ENST00000371632.7
LCN12
lipocalin 12
chr13_+_46553157 0.08 ENST00000311191.10
ENST00000389797.8
ENST00000389798.7
LRCH1
leucine rich repeats and calponin homology domain containing 1
chr17_+_7558258 0.08 ENST00000483039.5
ENST00000380535.8
ENST00000396542.5
TNFSF13
TNF superfamily member 13
chr17_-_41124178 0.08 ENST00000394014.2
KRTAP4-12
keratin associated protein 4-12
chr16_-_4416564 0.08 ENST00000572467.5
ENST00000251166.9
ENST00000572044.1
ENST00000571052.5
CORO7-PAM16
CORO7
CORO7-PAM16 readthrough
coronin 7
chr2_+_11612253 0.08 ENST00000396123.2
GREB1
growth regulating estrogen receptor binding 1
chr3_+_44584953 0.08 ENST00000441021.5
ENST00000322734.2
ZNF660
zinc finger protein 660
chr8_-_103415085 0.08 ENST00000297578.9
SLC25A32
solute carrier family 25 member 32
chr10_+_102065322 0.08 ENST00000299238.7
HPS6
HPS6 biogenesis of lysosomal organelles complex 2 subunit 3
chr19_+_11538844 0.08 ENST00000252456.7
CNN1
calponin 1
chr2_+_147845020 0.08 ENST00000241416.12
ACVR2A
activin A receptor type 2A
chr17_-_17577440 0.08 ENST00000395782.5
PEMT
phosphatidylethanolamine N-methyltransferase
chr1_+_43946905 0.08 ENST00000372343.8
IPO13
importin 13
chr16_+_641792 0.08 ENST00000307650.9
ENST00000629534.2
MCRIP2
MAPK regulated corepressor interacting protein 2
chr1_-_155978427 0.07 ENST00000313667.8
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2
chr7_-_712437 0.07 ENST00000360274.8
PRKAR1B
protein kinase cAMP-dependent type I regulatory subunit beta
chr14_-_105065422 0.07 ENST00000329797.8
ENST00000539291.6
ENST00000392585.2
GPR132
G protein-coupled receptor 132
chr1_+_151721508 0.07 ENST00000479191.2
RIIAD1
regulatory subunit of type II PKA R-subunit domain containing 1
chr19_+_11538767 0.07 ENST00000592923.5
ENST00000535659.6
CNN1
calponin 1
chr13_-_99086611 0.07 ENST00000427887.2
DOCK9
dedicator of cytokinesis 9
chr7_-_155809072 0.07 ENST00000430104.5
SHH
sonic hedgehog signaling molecule
chr2_+_60881553 0.07 ENST00000394479.4
REL
REL proto-oncogene, NF-kB subunit
chr17_-_7217206 0.07 ENST00000447163.6
ENST00000647975.1
DLG4
discs large MAGUK scaffold protein 4
chr2_+_98087160 0.06 ENST00000477737.6
VWA3B
von Willebrand factor A domain containing 3B
chr3_+_111859284 0.06 ENST00000498699.5
PHLDB2
pleckstrin homology like domain family B member 2
chr19_+_1026566 0.06 ENST00000562015.5
ENST00000263097.9
ENST00000348419.7
ENST00000565096.6
ENST00000562958.6
ENST00000568865.3
ENST00000606983.5
ENST00000562075.6
ENST00000607102.1
CNN2
calponin 2
chr15_-_42920638 0.06 ENST00000566931.1
ENST00000564431.5
ENST00000567274.5
ENST00000267890.11
TTBK2
tau tubulin kinase 2
chr19_+_55339867 0.06 ENST00000255613.8
KMT5C
lysine methyltransferase 5C
chr10_+_100987529 0.06 ENST00000370228.2
ENST00000311916.8
ENST00000473656.5
TWNK
twinkle mtDNA helicase
chr19_-_37906588 0.06 ENST00000447313.7
WDR87
WD repeat domain 87
chr7_-_727611 0.06 ENST00000403562.5
PRKAR1B
protein kinase cAMP-dependent type I regulatory subunit beta
chr11_-_69775338 0.06 ENST00000168712.3
FGF4
fibroblast growth factor 4
chr10_-_123008784 0.06 ENST00000368886.10
IKZF5
IKAROS family zinc finger 5
chr14_-_77498808 0.06 ENST00000342219.9
ENST00000493585.5
ENST00000554801.2
ISM2
isthmin 2
chr19_+_17281863 0.06 ENST00000652132.1
ENST00000404085.7
ENST00000598347.2
ANKLE1
ankyrin repeat and LEM domain containing 1
chr4_-_48080172 0.06 ENST00000507351.1
TXK
TXK tyrosine kinase
chr3_+_4493340 0.06 ENST00000357086.10
ENST00000354582.12
ENST00000649015.2
ENST00000467056.6
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
chr9_+_84669760 0.06 ENST00000304053.10
NTRK2
neurotrophic receptor tyrosine kinase 2
chr17_-_19867929 0.06 ENST00000361658.6
ENST00000395544.9
ULK2
unc-51 like autophagy activating kinase 2
chr16_+_84176067 0.06 ENST00000564928.1
DNAAF1
dynein axonemal assembly factor 1
chr3_+_111859796 0.06 ENST00000393925.7
PHLDB2
pleckstrin homology like domain family B member 2
chr19_-_48321857 0.06 ENST00000474199.6
ODAD1
outer dynein arm docking complex subunit 1
chrX_+_146809768 0.05 ENST00000438525.3
CXorf51B
chromosome X open reading frame 51B
chr22_-_30289607 0.05 ENST00000404953.7
CASTOR1
cytosolic arginine sensor for mTORC1 subunit 1
chr3_+_111859180 0.05 ENST00000412622.5
ENST00000431670.7
PHLDB2
pleckstrin homology like domain family B member 2
chr1_-_57424014 0.05 ENST00000371230.1
ENST00000371236.7
DAB1
DAB adaptor protein 1
chr8_+_66712700 0.05 ENST00000521198.7
SGK3
serum/glucocorticoid regulated kinase family member 3
chr11_-_68903796 0.05 ENST00000362034.7
MRPL21
mitochondrial ribosomal protein L21
chr15_+_89690804 0.05 ENST00000268130.12
ENST00000560294.5
ENST00000558000.1
WDR93
WD repeat domain 93
chr1_-_201154459 0.05 ENST00000414605.2
ENST00000367330.6
ENST00000367334.9
ENST00000367332.5
TMEM9
transmembrane protein 9
chr19_-_19138442 0.05 ENST00000587583.6
ENST00000450333.6
ENST00000587096.5
ENST00000162044.14
ENST00000592369.1
ENST00000587915.1
TMEM161A
transmembrane protein 161A
chr3_-_193378747 0.05 ENST00000342358.9
ATP13A5
ATPase 13A5
chr16_+_27066919 0.05 ENST00000505035.3
C16orf82
chromosome 16 open reading frame 82
chr3_+_4493442 0.05 ENST00000456211.8
ENST00000443694.5
ENST00000648266.1
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
chr6_-_39322968 0.05 ENST00000507712.5
KCNK16
potassium two pore domain channel subfamily K member 16
chr17_-_28897724 0.05 ENST00000394908.9
FLOT2
flotillin 2
chr12_+_112125531 0.05 ENST00000549358.5
ENST00000257604.9
ENST00000548092.5
ENST00000412615.7
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr1_-_201115372 0.05 ENST00000458416.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr16_-_29923237 0.05 ENST00000568995.1
ENST00000566413.1
KCTD13
potassium channel tetramerization domain containing 13
chr20_-_62220267 0.05 ENST00000317393.10
ENST00000611492.1
ENST00000340177.10
HRH3
histamine receptor H3
chr19_+_17859885 0.05 ENST00000222247.10
ENST00000600147.5
ENST00000599898.5
RPL18A
ribosomal protein L18a
chr1_-_235128819 0.05 ENST00000366607.5
TOMM20
translocase of outer mitochondrial membrane 20
chr10_-_13234368 0.05 ENST00000378681.8
UCMA
upper zone of growth plate and cartilage matrix associated
chr15_-_42920798 0.04 ENST00000622375.4
ENST00000567840.5
TTBK2
tau tubulin kinase 2
chr10_-_13234329 0.04 ENST00000463405.2
UCMA
upper zone of growth plate and cartilage matrix associated
chr8_+_143213192 0.04 ENST00000622500.2
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr6_-_41072529 0.04 ENST00000373154.6
ENST00000464633.5
ENST00000628419.2
ENST00000479950.5
ENST00000482515.5
OARD1
O-acyl-ADP-ribose deacylase 1
chr11_-_57322197 0.04 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1
chr9_+_113594118 0.04 ENST00000620489.1
RGS3
regulator of G protein signaling 3
chr4_-_105473709 0.04 ENST00000502596.5
PPA2
inorganic pyrophosphatase 2
chr22_+_22644475 0.04 ENST00000618722.4
ENST00000652219.1
ENST00000480559.6
ENST00000448514.2
ENST00000652249.1
ENST00000651213.1
GGTLC2
gamma-glutamyltransferase light chain 2
chr4_+_163343882 0.04 ENST00000338566.8
NPY5R
neuropeptide Y receptor Y5
chr19_-_10333512 0.04 ENST00000617231.5
ENST00000611074.4
ENST00000615032.4
RAVER1
ribonucleoprotein, PTB binding 1
chr19_+_37907200 0.04 ENST00000222345.11
SIPA1L3
signal induced proliferation associated 1 like 3
chr19_+_41755520 0.04 ENST00000199764.7
CEACAM6
CEA cell adhesion molecule 6
chr12_-_48716998 0.04 ENST00000618666.4
CCNT1
cyclin T1
chr6_-_79537423 0.04 ENST00000369846.9
ENST00000392959.5
ENST00000467898.3
LCA5
lebercilin LCA5
chr13_-_94596145 0.04 ENST00000261296.7
TGDS
TDP-glucose 4,6-dehydratase
chr19_+_45079195 0.04 ENST00000591607.1
ENST00000591747.5
ENST00000270257.9
ENST00000391951.2
ENST00000587566.5
GEMIN7
MARK4
gem nuclear organelle associated protein 7
microtubule affinity regulating kinase 4
chr1_-_27374816 0.04 ENST00000270879.9
ENST00000354982.2
FCN3
ficolin 3
chr19_+_44751251 0.04 ENST00000444487.1
BCL3
BCL3 transcription coactivator
chr1_-_114757971 0.04 ENST00000261443.9
ENST00000534699.5
ENST00000339438.10
ENST00000358528.9
ENST00000529046.5
ENST00000525970.5
ENST00000369530.5
ENST00000530886.5
ENST00000610726.4
CSDE1
cold shock domain containing E1
chr19_-_48321948 0.04 ENST00000674294.1
ODAD1
outer dynein arm docking complex subunit 1
chr16_-_29899532 0.04 ENST00000308713.9
ENST00000617533.5
SEZ6L2
seizure related 6 homolog like 2
chr16_+_32252719 0.04 ENST00000398664.4
TP53TG3D
TP53 target 3D
chr17_-_5234801 0.04 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chr19_-_55280063 0.04 ENST00000593263.5
ENST00000433386.7
HSPBP1
HSPA (Hsp70) binding protein 1
chr6_-_99568611 0.04 ENST00000369217.8
ENST00000369220.8
ENST00000482541.2
ENST00000520429.6
ENST00000523985.5
ENST00000518714.5
CCNC
cyclin C
chr16_+_70646536 0.04 ENST00000288098.6
IL34
interleukin 34
chr2_+_231592858 0.04 ENST00000313965.4
TEX44
testis expressed 44
chr19_+_1407653 0.04 ENST00000587079.5
DAZAP1
DAZ associated protein 1
chr21_-_41879294 0.04 ENST00000398548.6
ENST00000422911.6
ENST00000269844.5
PRDM15
PR/SET domain 15
chr22_+_50738198 0.04 ENST00000216139.10
ENST00000529621.1
ACR
acrosin
chr7_-_727242 0.04 ENST00000537384.6
ENST00000417852.5
PRKAR1B
protein kinase cAMP-dependent type I regulatory subunit beta
chr17_-_76072486 0.03 ENST00000629930.1
ENST00000539137.5
ENST00000307877.7
SRP68
signal recognition particle 68
chr6_+_143843316 0.03 ENST00000367576.6
LTV1
LTV1 ribosome biogenesis factor
chr19_-_42427379 0.03 ENST00000244289.9
LIPE
lipase E, hormone sensitive type
chr15_+_69014689 0.03 ENST00000388866.8
ENST00000530406.6
NOX5
NADPH oxidase 5

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0001794 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.1 0.5 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.1 0.5 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.3 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.5 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.4 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.1 0.4 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) positive regulation of leukocyte tethering or rolling(GO:1903238)
0.1 0.4 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 0.3 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.1 0.4 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.6 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.1 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.2 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.1 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.4 GO:1903236 regulation of leukocyte tethering or rolling(GO:1903236)
0.0 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.1 GO:0060775 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.0 0.2 GO:0097114 NMDA glutamate receptor clustering(GO:0097114)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.4 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.1 GO:0060458 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) kidney smooth muscle tissue development(GO:0072194) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:1903576 response to L-arginine(GO:1903576)
0.0 0.1 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) cellular response to progesterone stimulus(GO:0071393)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.0 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.0 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.4 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.0 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.0 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.0 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 1.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.5 GO:0042627 chylomicron(GO:0042627)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.0 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.0 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.0 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.8 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 1.3 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.4 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.9 GO:0019841 retinol binding(GO:0019841)
0.0 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.3 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.0 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.7 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway