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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for GLIS3

Z-value: 0.35

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Transcription factors associated with GLIS3

Gene Symbol Gene ID Gene Info
ENSG00000107249.24 GLIS family zinc finger 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS3hg38_v1_chr9_-_4300049_4300120,
hg38_v1_chr9_-_4299547_4299597
-0.029.6e-01Click!

Activity profile of GLIS3 motif

Sorted Z-values of GLIS3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_209806124 0.24 ENST00000367021.8
ENST00000542854.5
interferon regulatory factor 6
chr6_+_89081787 0.22 ENST00000354922.3
proline rich nuclear receptor coactivator 1
chr18_+_11752041 0.22 ENST00000423027.8
G protein subunit alpha L
chr12_+_52949107 0.21 ENST00000388835.4
keratin 18
chr17_-_79952007 0.19 ENST00000574241.6
TBC1 domain family member 16
chr20_+_21126037 0.14 ENST00000611685.4
ENST00000616848.4
kizuna centrosomal protein
chr20_+_21125999 0.13 ENST00000620891.4
kizuna centrosomal protein
chr20_+_21125981 0.13 ENST00000619574.4
kizuna centrosomal protein
chr18_+_11751494 0.13 ENST00000269162.9
G protein subunit alpha L
chr20_+_21126074 0.12 ENST00000619189.5
kizuna centrosomal protein
chr14_+_104724221 0.11 ENST00000330877.7
adenylosuccinate synthase 1
chr11_-_68903796 0.10 ENST00000362034.7
mitochondrial ribosomal protein L21
chr18_+_3451585 0.10 ENST00000551541.5
TGFB induced factor homeobox 1
chr19_+_40775154 0.10 ENST00000594436.5
ENST00000597784.5
MIA SH3 domain containing
chr17_-_75182536 0.09 ENST00000578238.2
small ubiquitin like modifier 2
chr19_-_55580829 0.09 ENST00000592239.1
ENST00000325421.7
zinc finger protein 579
chr13_-_20192928 0.08 ENST00000382848.5
gap junction protein beta 2
chr6_+_33204645 0.08 ENST00000374662.4
hydroxysteroid 17-beta dehydrogenase 8
chr16_-_90008988 0.08 ENST00000568662.2
dysbindin domain containing 1
chr8_-_73878816 0.08 ENST00000602593.6
ENST00000651945.1
ENST00000419880.7
ENST00000517608.5
ENST00000650817.1
ubiquitin conjugating enzyme E2 W
chr2_-_207165923 0.08 ENST00000309446.11
Kruppel like factor 7
chr18_+_3451647 0.07 ENST00000345133.9
ENST00000330513.10
ENST00000549546.5
TGFB induced factor homeobox 1
chr19_-_42255119 0.07 ENST00000222329.9
ENST00000594664.1
ETS2 repressor factor
novel protein
chr17_+_4771878 0.07 ENST00000270560.4
transmembrane 4 L six family member 5
chr11_+_68684534 0.07 ENST00000265643.4
galanin and GMAP prepropeptide
chr8_+_11769696 0.07 ENST00000455213.6
ENST00000403422.7
ENST00000528323.5
ENST00000284503.7
nei like DNA glycosylase 2
chr3_+_173398438 0.06 ENST00000457714.5
neuroligin 1
chr10_-_74163 0.06 ENST00000564130.2
tubulin beta 8 class VIII
chr6_-_44265541 0.06 ENST00000619360.6
NFKB inhibitor epsilon
chr8_+_11769639 0.06 ENST00000436750.7
nei like DNA glycosylase 2
chr15_-_43590155 0.05 ENST00000453080.5
ENST00000360135.8
ENST00000360301.8
ENST00000417085.2
ENST00000431962.1
ENST00000334933.8
ENST00000381879.8
ENST00000420765.5
diphosphoinositol pentakisphosphate kinase 1
chr5_-_132777229 0.05 ENST00000378721.8
ENST00000378719.7
ENST00000378701.5
septin 8
chr17_-_75182949 0.05 ENST00000314523.7
ENST00000420826.7
small ubiquitin like modifier 2
chr17_+_7888783 0.05 ENST00000330494.12
ENST00000358181.8
chromodomain helicase DNA binding protein 3
chr22_+_50190569 0.05 ENST00000395827.5
TraB domain containing
chr19_-_3061403 0.05 ENST00000586839.1
TLE family member 5, transcriptional modulator
chr1_-_19799872 0.04 ENST00000294543.11
transmembrane and coiled-coil domains 4
chr1_-_160285120 0.04 ENST00000368072.10
peroxisomal biogenesis factor 19
chr15_+_83447411 0.04 ENST00000324537.5
SH3 domain containing GRB2 like 3, endophilin A3
chr2_-_85602351 0.04 ENST00000409668.1
transmembrane protein 150A
chr17_+_47941562 0.04 ENST00000225573.5
ENST00000434554.7
ENST00000642017.2
pyridoxamine 5'-phosphate oxidase
chr1_-_45521854 0.04 ENST00000372079.1
ENST00000319248.13
peroxiredoxin 1
chr1_+_31413806 0.04 ENST00000536384.2
serine incorporator 2
chr20_-_31722854 0.04 ENST00000307677.5
BCL2 like 1
chr21_-_44910630 0.04 ENST00000320216.10
ENST00000397852.5
integrin subunit beta 2
chr2_-_85602681 0.03 ENST00000334462.10
ENST00000306353.7
transmembrane protein 150A
chr1_+_107056656 0.03 ENST00000370078.2
protein arginine methyltransferase 6
chr1_-_45521931 0.03 ENST00000447184.6
ENST00000262746.5
peroxiredoxin 1
chr12_+_54008961 0.03 ENST00000040584.6
homeobox C8
chr19_+_12945839 0.03 ENST00000586534.6
ENST00000316856.7
ENST00000592268.5
RAD23 homolog A, nucleotide excision repair protein
chr19_+_41354145 0.03 ENST00000604123.5
transmembrane protein 91
chr22_+_22644475 0.03 ENST00000618722.4
ENST00000652219.1
ENST00000480559.6
ENST00000448514.2
ENST00000652249.1
ENST00000651213.1
gamma-glutamyltransferase light chain 2
chr6_+_24494939 0.03 ENST00000348925.2
ENST00000357578.8
aldehyde dehydrogenase 5 family member A1
chr10_-_125161019 0.03 ENST00000411419.6
C-terminal binding protein 2
chr9_-_95516959 0.03 ENST00000437951.6
ENST00000430669.6
ENST00000468211.6
patched 1
chr19_-_14114156 0.03 ENST00000589994.6
protein kinase cAMP-activated catalytic subunit alpha
chr14_+_22462932 0.03 ENST00000390477.2
T cell receptor delta constant
chr5_+_172959416 0.02 ENST00000265100.6
ENST00000519239.5
ribosomal protein L26 like 1
chr17_-_58527980 0.02 ENST00000583114.5
septin 4
chr17_-_5111836 0.02 ENST00000575898.5
zinc finger protein 232
chr11_-_18791563 0.02 ENST00000396168.1
protein tyrosine phosphatase non-receptor type 5
chr19_-_37906646 0.02 ENST00000303868.5
WD repeat domain 87
chr1_-_45522870 0.02 ENST00000424390.2
peroxiredoxin 1
chr5_-_132777344 0.02 ENST00000378706.5
septin 8
chr17_+_50834581 0.02 ENST00000426127.1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr16_+_89620584 0.02 ENST00000393092.7
dipeptidase 1
chr3_+_127629161 0.02 ENST00000342480.7
podocalyxin like 2
chrX_-_48957871 0.02 ENST00000610466.4
OTU deubiquitinase 5
chr4_-_83334782 0.02 ENST00000681769.1
ENST00000513463.1
ENST00000311412.10
heparanase
chr5_+_41925223 0.01 ENST00000296812.6
ENST00000281623.8
ENST00000509134.1
F-box protein 4
chr3_+_37987970 0.01 ENST00000283713.10
villin like
chr20_-_31723491 0.01 ENST00000676582.1
ENST00000422920.2
BCL2 like 1
chr18_-_48950960 0.01 ENST00000262158.8
SMAD family member 7
chr5_+_172959511 0.01 ENST00000519522.1
ribosomal protein L26 like 1
chr18_+_11751467 0.01 ENST00000535121.5
G protein subunit alpha L
chr5_-_132777215 0.01 ENST00000458488.2
septin 8
chr17_+_50835578 0.01 ENST00000311378.5
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr22_-_50526337 0.01 ENST00000651490.1
ENST00000543927.6
thymidine phosphorylase
synthesis of cytochrome C oxidase 2
chr19_-_37906588 0.01 ENST00000447313.7
WD repeat domain 87
chr1_-_42335869 0.01 ENST00000372573.5
forkhead box J3
chr5_-_132777371 0.01 ENST00000620483.4
septin 8
chr3_-_25783381 0.01 ENST00000308710.9
ENST00000676225.1
N-glycanase 1
chr5_-_179623659 0.00 ENST00000519056.5
ENST00000506721.5
ENST00000503105.5
ENST00000504348.5
ENST00000508103.5
ENST00000510431.5
ENST00000515158.5
ENST00000393432.8
ENST00000442819.6
heterogeneous nuclear ribonucleoprotein H1
chr19_+_1275508 0.00 ENST00000409293.6
family with sequence similarity 174 member C
chr9_-_136764515 0.00 ENST00000316144.6
lipocalin 15
chr19_+_46347063 0.00 ENST00000012443.9
ENST00000391919.1
protein phosphatase 5 catalytic subunit
chr15_+_90935277 0.00 ENST00000418476.2
unc-45 myosin chaperone A
chr5_-_132777404 0.00 ENST00000296873.11
septin 8
chr11_+_68903849 0.00 ENST00000675615.1
ENST00000255078.8
immunoglobulin mu DNA binding protein 2
chr1_-_42335189 0.00 ENST00000361776.5
ENST00000445886.5
ENST00000361346.6
forkhead box J3
chr19_+_43984167 0.00 ENST00000611002.4
ENST00000270014.7
ENST00000591532.5
ENST00000407951.6
ENST00000590615.5
ENST00000586454.1
zinc finger protein 155
chr3_-_25783434 0.00 ENST00000396649.7
ENST00000280700.10
ENST00000428257.5
N-glycanase 1
chrX_-_126552801 0.00 ENST00000371126.3
DDB1 and CUL4 associated factor 12 like 1
chr1_+_2019379 0.00 ENST00000638771.1
ENST00000640949.1
ENST00000640030.1
gamma-aminobutyric acid type A receptor subunit delta
chr17_-_3916455 0.00 ENST00000225538.4
purinergic receptor P2X 1
chr12_-_47758828 0.00 ENST00000389212.7
ENST00000449771.7
Rap guanine nucleotide exchange factor 3

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043000 Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.1 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.0 0.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.0 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.0 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0034970 histone H3-R2 methylation(GO:0034970)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway