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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for GUAGUGU

Z-value: 0.69

Motif logo

miRNA associated with seed GUAGUGU

NamemiRBASE accession
MIMAT0000434

Activity profile of GUAGUGU motif

Sorted Z-values of GUAGUGU motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_95731300 0.71 ENST00000379982.8
Rho related BTB domain containing 3
chrX_+_9463272 0.32 ENST00000407597.7
ENST00000380961.5
ENST00000424279.6
transducin beta like 1 X-linked
chr4_+_144646145 0.31 ENST00000296575.8
ENST00000434550.2
hedgehog interacting protein
chr9_+_88991440 0.28 ENST00000358157.3
sphingosine-1-phosphate receptor 3
chr20_+_34704336 0.27 ENST00000374809.6
ENST00000374810.8
ENST00000451665.5
tumor protein p53 inducible nuclear protein 2
chr21_-_37916440 0.25 ENST00000609713.2
potassium inwardly rectifying channel subfamily J member 6
chr10_-_79445617 0.23 ENST00000372336.4
zinc finger CCHC-type containing 24
chr12_-_46825949 0.21 ENST00000547477.5
ENST00000447411.5
ENST00000266579.9
solute carrier family 38 member 4
chr3_+_20040437 0.19 ENST00000263754.5
lysine acetyltransferase 2B
chr4_+_15002443 0.18 ENST00000538197.7
cytoplasmic polyadenylation element binding protein 2
chr4_+_38867789 0.18 ENST00000358869.5
family with sequence similarity 114 member A1
chr20_-_47355657 0.16 ENST00000311275.11
zinc finger MYND-type containing 8
chr8_+_80485641 0.15 ENST00000430430.5
zinc finger and BTB domain containing 10
chr5_-_91383310 0.14 ENST00000265138.4
arrestin domain containing 3
chr2_-_43226594 0.14 ENST00000282388.4
ZFP36 ring finger protein like 2
chr3_+_156674579 0.13 ENST00000295924.12
TCDD inducible poly(ADP-ribose) polymerase
chr17_+_29390326 0.12 ENST00000261716.8
TAO kinase 1
chr10_-_27240743 0.12 ENST00000677901.1
ENST00000677960.1
ENST00000677440.1
ENST00000396271.8
ENST00000677141.1
ENST00000677311.1
ENST00000677667.1
ENST00000677200.1
ENST00000676997.1
ENST00000676511.1
acyl-CoA binding domain containing 5
chr20_-_31722533 0.12 ENST00000677194.1
ENST00000434194.2
ENST00000376062.6
BCL2 like 1
chr15_-_78077657 0.11 ENST00000300584.8
ENST00000409931.7
TBC1 domain family member 2B
chr14_-_34713788 0.11 ENST00000341223.8
cofilin 2
chr15_+_38252792 0.11 ENST00000299084.9
sprouty related EVH1 domain containing 1
chr10_+_61901678 0.11 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
AT-rich interaction domain 5B
chr14_+_52552830 0.11 ENST00000321662.11
G protein-coupled receptor 137C
chr17_+_57256514 0.10 ENST00000284073.7
ENST00000674964.1
musashi RNA binding protein 2
chr13_+_48975879 0.10 ENST00000492622.6
fibronectin type III domain containing 3A
chr2_+_178480446 0.10 ENST00000234453.10
pleckstrin homology domain containing A3
chr10_-_59906509 0.09 ENST00000263102.7
coiled-coil domain containing 6
chr17_-_8630713 0.09 ENST00000411957.1
ENST00000360416.8
myosin heavy chain 10
chr17_-_76240478 0.09 ENST00000269391.11
ring finger protein 157
chrX_+_135032346 0.09 ENST00000257013.9
retrotransposon Gag like 8C
chr9_-_27573391 0.09 ENST00000644136.1
ENST00000380003.8
C9orf72-SMCR8 complex subunit
chr12_+_65824475 0.09 ENST00000403681.7
high mobility group AT-hook 2
chr6_-_30617232 0.08 ENST00000376511.7
protein phosphatase 1 regulatory subunit 10
chr20_-_4015389 0.08 ENST00000336095.10
ring finger protein 24
chr1_+_113929600 0.07 ENST00000369558.5
ENST00000369561.8
homeodomain interacting protein kinase 1
chr1_+_7771263 0.07 ENST00000054666.11
vesicle associated membrane protein 3
chr16_+_10877181 0.07 ENST00000618207.4
ENST00000618327.4
ENST00000324288.14
ENST00000381835.9
class II major histocompatibility complex transactivator
chr16_-_18926408 0.07 ENST00000446231.7
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr21_-_43427131 0.06 ENST00000270162.8
salt inducible kinase 1
chr13_-_30464234 0.06 ENST00000399489.5
ENST00000339872.8
high mobility group box 1
chr20_-_5610980 0.06 ENST00000379019.7
glycerophosphocholine phosphodiesterase 1
chr11_-_77820706 0.06 ENST00000440064.2
ENST00000528095.5
ENST00000308488.11
remodeling and spacing factor 1
chr5_-_134176920 0.06 ENST00000521216.5
ENST00000353411.11
ENST00000522855.5
ENST00000328392.10
ENST00000519321.5
S-phase kinase associated protein 1
chr16_+_28863757 0.06 ENST00000618521.4
ENST00000359285.9
ENST00000538342.5
SH2B adaptor protein 1
chr1_-_205750167 0.06 ENST00000367142.5
nuclear casein kinase and cyclin dependent kinase substrate 1
chr2_-_11344580 0.06 ENST00000616279.4
ENST00000315872.11
Rho associated coiled-coil containing protein kinase 2
chr3_+_129249594 0.06 ENST00000314797.10
COPI coat complex subunit gamma 1
chr12_+_8697875 0.06 ENST00000357529.7
ribosomal modification protein rimK like family member B
chr2_-_86721122 0.06 ENST00000604011.5
RNF103-CHMP3 readthrough
chr3_-_115071333 0.05 ENST00000462705.5
zinc finger and BTB domain containing 20
chr5_-_102296260 0.05 ENST00000310954.7
solute carrier organic anion transporter family member 4C1
chr11_+_58579052 0.05 ENST00000316059.7
ZFP91 zinc finger protein, atypical E3 ubiquitin ligase
chr18_+_70288991 0.05 ENST00000397942.4
suppressor of cytokine signaling 6
chr10_+_96043394 0.05 ENST00000403870.7
ENST00000265992.9
ENST00000465148.3
cyclin J
chr5_-_143403611 0.05 ENST00000394464.7
ENST00000231509.7
nuclear receptor subfamily 3 group C member 1
chr6_-_136289824 0.05 ENST00000527536.5
ENST00000529826.5
ENST00000531224.6
ENST00000353331.8
ENST00000628517.2
BCL2 associated transcription factor 1
chr2_+_203328378 0.05 ENST00000430418.5
ENST00000261018.12
ENST00000295851.10
ENST00000424558.5
ENST00000417864.5
ENST00000422511.6
abl interactor 2
chr22_-_31346143 0.05 ENST00000405309.7
ENST00000351933.8
POZ/BTB and AT hook containing zinc finger 1
chr10_+_132537778 0.05 ENST00000368594.8
inositol polyphosphate-5-phosphatase A
chr2_+_209579399 0.05 ENST00000360351.8
microtubule associated protein 2
chr5_-_32444722 0.05 ENST00000265069.13
zinc finger RNA binding protein
chr8_+_60516947 0.04 ENST00000262646.12
RAB2A, member RAS oncogene family
chr15_-_50765656 0.04 ENST00000261854.10
signal peptide peptidase like 2A
chr6_-_36986122 0.04 ENST00000460219.2
ENST00000373627.10
ENST00000373616.9
mitochondrial carrier 1
chr14_+_57268963 0.04 ENST00000261558.8
adaptor related protein complex 5 subunit mu 1
chr5_+_134845935 0.04 ENST00000394976.4
chromosome 5 open reading frame 24
chr12_-_101407727 0.04 ENST00000539055.5
ENST00000551688.1
ENST00000551671.5
ENST00000261636.13
ADP ribosylation factor like GTPase 1
chr17_+_2796404 0.04 ENST00000366401.8
ENST00000254695.13
ENST00000542807.1
RAP1 GTPase activating protein 2
chr4_+_6640676 0.04 ENST00000382581.5
ENST00000507420.1
Morf4 family associated protein 1
chrX_-_103688033 0.04 ENST00000434230.5
ENST00000418819.5
ENST00000360458.5
mortality factor 4 like 2
chr1_+_32179665 0.04 ENST00000373610.8
taxilin alpha
chr14_+_64986846 0.04 ENST00000246166.3
farnesyltransferase, CAAX box, beta
chr17_-_4263847 0.04 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ankyrin repeat and FYVE domain containing 1
chr1_+_11012622 0.04 ENST00000629725.2
ENST00000476201.5
ENST00000240185.8
ENST00000621715.4
TAR DNA binding protein
chr7_+_100673732 0.04 ENST00000303210.9
ENST00000436220.5
ENST00000424361.5
G protein subunit beta 2
chr2_-_68252482 0.04 ENST00000234310.8
protein phosphatase 3 regulatory subunit B, alpha
chr1_+_218345326 0.04 ENST00000366930.9
transforming growth factor beta 2
chr22_-_35840218 0.04 ENST00000414461.6
ENST00000416721.6
ENST00000449924.6
ENST00000262829.11
ENST00000397305.3
RNA binding fox-1 homolog 2
chr4_-_72569204 0.04 ENST00000286657.10
ADAM metallopeptidase with thrombospondin type 1 motif 3
chr6_+_13615322 0.04 ENST00000451315.7
nucleolar protein 7
chr11_+_120336357 0.04 ENST00000397843.7
Rho guanine nucleotide exchange factor 12
chr18_-_26090584 0.04 ENST00000415083.7
SS18 subunit of BAF chromatin remodeling complex
chr11_+_118436464 0.03 ENST00000389506.10
ENST00000534358.8
ENST00000531904.6
ENST00000649699.1
lysine methyltransferase 2A
chrX_-_135052114 0.03 ENST00000370775.3
retrotransposon Gag like 8A
chr1_-_155562693 0.03 ENST00000368346.7
ENST00000392403.8
ENST00000679333.1
ENST00000679133.1
ASH1 like histone lysine methyltransferase
chr14_-_20461411 0.03 ENST00000250489.9
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
chr15_-_52529050 0.03 ENST00000399231.7
myosin VA
chr9_-_14314067 0.03 ENST00000397575.7
nuclear factor I B
chrX_-_41922992 0.03 ENST00000646120.2
ENST00000421587.8
ENST00000644770.1
ENST00000645566.1
ENST00000378166.9
ENST00000378158.6
ENST00000644219.1
ENST00000442742.7
ENST00000644347.1
calcium/calmodulin dependent serine protein kinase
chr5_+_141245384 0.03 ENST00000623671.1
ENST00000231173.6
protocadherin beta 15
chr14_-_31207758 0.03 ENST00000399332.6
ENST00000553700.5
HECT domain E3 ubiquitin protein ligase 1
chr12_-_117190456 0.03 ENST00000330622.9
ENST00000622495.5
ENST00000427718.6
F-box protein 21
chr1_+_27773189 0.03 ENST00000373943.9
ENST00000440806.2
syntaxin 12
chr2_+_42169332 0.03 ENST00000402711.6
ENST00000318522.10
EMAP like 4
chr9_-_124941054 0.03 ENST00000373555.9
golgin A1
chr2_+_197515565 0.03 ENST00000233892.8
ENST00000409916.5
MOB family member 4, phocein
chr3_-_177196451 0.03 ENST00000430069.5
ENST00000630796.2
ENST00000428970.5
TBL1X receptor 1
chrX_+_28587411 0.03 ENST00000378993.6
interleukin 1 receptor accessory protein like 1
chr11_+_126283059 0.03 ENST00000392679.6
ENST00000392678.7
ENST00000392680.6
TIR domain containing adaptor protein
chr1_+_24745396 0.03 ENST00000374379.9
chloride intracellular channel 4
chr10_+_17644126 0.03 ENST00000377524.8
signal transducing adaptor molecule
chr2_+_197500398 0.03 ENST00000604458.1
HSPE1-MOB4 readthrough
chr3_-_112499457 0.03 ENST00000334529.10
B and T lymphocyte associated
chr7_-_44885446 0.03 ENST00000395699.5
purine rich element binding protein B
chr1_+_86704564 0.02 ENST00000616170.4
ENST00000535010.5
ENST00000370558.8
SH3 domain containing GRB2 like, endophilin B1
chr3_+_196568611 0.02 ENST00000440469.1
ENST00000311630.7
F-box protein 45
chr12_+_64610458 0.02 ENST00000542104.6
Ras association domain family member 3
chr11_-_796185 0.02 ENST00000533385.5
ENST00000528936.5
ENST00000629634.2
ENST00000625752.2
ENST00000528606.5
ENST00000320230.9
solute carrier family 25 member 22
chr3_+_23945271 0.02 ENST00000312521.9
nuclear receptor subfamily 1 group D member 2
chr6_+_163414637 0.02 ENST00000453779.6
ENST00000275262.11
ENST00000392127.6
QKI, KH domain containing RNA binding
chr5_-_173616588 0.02 ENST00000285908.5
ENST00000311086.9
ENST00000480951.1
biorientation of chromosomes in cell division 1
chr1_+_77779618 0.02 ENST00000370791.7
ENST00000443751.3
ENST00000645756.1
ENST00000643390.1
ENST00000642959.1
mitoguardin 1
chr5_-_157059109 0.02 ENST00000523175.6
ENST00000522693.5
hepatitis A virus cellular receptor 1
chr2_-_152175715 0.02 ENST00000263904.5
signal transducing adaptor molecule 2
chr2_-_160493799 0.02 ENST00000348849.8
RNA binding motif single stranded interacting protein 1
chr6_-_73653913 0.02 ENST00000355773.6
solute carrier family 17 member 5
chr20_+_8132138 0.02 ENST00000378641.7
ENST00000338037.11
ENST00000629992.2
phospholipase C beta 1
chr14_+_64914361 0.02 ENST00000607599.6
ENST00000548752.7
ENST00000551947.6
ENST00000549115.7
ENST00000552002.7
ENST00000551093.6
ENST00000549987.1
churchill domain containing 1
CHURC1-FNTB readthrough
chr4_-_128287785 0.02 ENST00000296425.10
progesterone receptor membrane component 2
chr10_-_58267868 0.02 ENST00000373935.4
inositol polyphosphate multikinase
chr9_-_78031775 0.02 ENST00000286548.9
G protein subunit alpha q
chr4_+_86934976 0.02 ENST00000507468.5
ENST00000395146.9
AF4/FMR2 family member 1
chr8_+_9555900 0.02 ENST00000310430.11
ENST00000520408.5
ENST00000522110.1
tankyrase
chr11_+_122838492 0.01 ENST00000227348.9
cytotoxic and regulatory T cell molecule
chr6_-_134318097 0.01 ENST00000367858.10
ENST00000533224.1
serum/glucocorticoid regulated kinase 1
chr15_+_71096941 0.01 ENST00000355327.7
thrombospondin type 1 domain containing 4
chr15_+_78872809 0.01 ENST00000331268.9
mortality factor 4 like 1
chr7_+_106865474 0.01 ENST00000359195.3
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr7_-_6484057 0.01 ENST00000490996.1
ENST00000258739.9
ENST00000436575.5
KDEL endoplasmic reticulum protein retention receptor 2
diacylglycerol lipase beta
chr5_+_146203593 0.01 ENST00000265271.7
RNA binding motif protein 27
chr16_-_66751591 0.01 ENST00000440564.6
ENST00000443351.6
ENST00000566150.5
ENST00000258198.7
dynein cytoplasmic 1 light intermediate chain 2
chr10_-_118046922 0.01 ENST00000355624.8
RAB11 family interacting protein 2
chr17_-_64263221 0.01 ENST00000258991.7
ENST00000583738.1
ENST00000584379.6
testis expressed 2
chr9_-_36400260 0.01 ENST00000259605.11
ENST00000353739.8
ENST00000611646.4
ring finger protein 38
chr20_+_37289633 0.01 ENST00000397150.5
ENST00000373606.8
ENST00000397152.7
mannosidase beta like
chr16_-_74666839 0.01 ENST00000576652.1
ENST00000572337.5
ENST00000571750.5
ENST00000572990.5
ENST00000361070.9
ring finger and WD repeat domain 3
chr1_+_115641945 0.01 ENST00000355485.7
ENST00000369510.8
VANGL planar cell polarity protein 1
chr21_-_38498415 0.01 ENST00000398905.5
ENST00000398907.5
ENST00000453032.6
ENST00000288319.12
ETS transcription factor ERG
chr1_-_91021455 0.01 ENST00000347275.9
ENST00000370440.5
zinc finger protein 644
chr16_+_590056 0.01 ENST00000248139.8
ENST00000568586.5
ENST00000538492.5
RAB40C, member RAS oncogene family
chr12_-_54188871 0.01 ENST00000504338.5
ENST00000514685.5
ENST00000504797.1
ENST00000513838.5
ENST00000505128.5
ENST00000337581.7
ENST00000503306.5
ENST00000243112.9
ENST00000514196.5
ENST00000682136.1
ENST00000506169.5
ENST00000507904.5
ENST00000508394.6
single-strand-selective monofunctional uracil-DNA glycosylase 1
chr7_-_5423543 0.01 ENST00000399537.8
trinucleotide repeat containing 18
chr14_-_81220951 0.01 ENST00000553612.6
general transcription factor IIA subunit 1
chrX_-_154019800 0.01 ENST00000444230.5
ENST00000393687.6
ENST00000429936.6
ENST00000369974.6
ENST00000369980.8
interleukin 1 receptor associated kinase 1
chr20_-_62937936 0.01 ENST00000266070.8
ENST00000370371.8
death inducer-obliterator 1
chrX_+_49922605 0.01 ENST00000376088.7
chloride voltage-gated channel 5
chr3_+_94062974 0.01 ENST00000314622.9
NOP2/Sun RNA methyltransferase 3
chr1_+_224356852 0.01 ENST00000366858.7
ENST00000366857.9
ENST00000465271.6
ENST00000366856.3
cornichon family AMPA receptor auxiliary protein 4
chr5_-_115625972 0.00 ENST00000333314.3
ENST00000456936.4
TMED7-TICAM2 readthrough
transmembrane p24 trafficking protein 7
chr16_+_71845958 0.00 ENST00000427980.7
ENST00000568581.5
ataxin 1 like
IST1 factor associated with ESCRT-III
chr2_-_65130090 0.00 ENST00000398529.7
ENST00000409751.1
ENST00000409892.5
ENST00000409784.8
RAB1A, member RAS oncogene family
chr4_-_16084002 0.00 ENST00000447510.7
prominin 1
chr1_+_213987929 0.00 ENST00000498508.6
ENST00000366958.9
prospero homeobox 1
chr9_+_36190856 0.00 ENST00000433436.6
ENST00000538225.5
ENST00000540080.5
clathrin light chain A
chr8_+_98426943 0.00 ENST00000287042.5
potassium voltage-gated channel modifier subfamily S member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAGUGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.2 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.1 GO:0031049 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.0 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868)
0.0 0.0 GO:2001025 positive regulation of response to drug(GO:2001025) regulation of cellular response to drug(GO:2001038)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.0 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression