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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for GUCAGUU

Z-value: 0.72

Motif logo

miRNA associated with seed GUCAGUU

NamemiRBASE accession
MIMAT0000280

Activity profile of GUCAGUU motif

Sorted Z-values of GUCAGUU motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_96493803 0.50 ENST00000518385.5
ENST00000302190.9
syndecan 2
chr5_+_72107453 0.33 ENST00000296755.12
ENST00000511641.2
microtubule associated protein 1B
chr7_-_19117625 0.20 ENST00000242261.6
twist family bHLH transcription factor 1
chr1_-_91886144 0.18 ENST00000212355.9
transforming growth factor beta receptor 3
chr2_-_157444044 0.18 ENST00000264192.8
cytohesin 1 interacting protein
chr10_+_93993897 0.15 ENST00000371380.8
phospholipase C epsilon 1
chr5_-_127030545 0.15 ENST00000308660.6
membrane associated ring-CH-type finger 3
chr2_+_20447065 0.14 ENST00000272233.6
ras homolog family member B
chr16_-_73048104 0.13 ENST00000268489.10
zinc finger homeobox 3
chr12_-_31591129 0.13 ENST00000389082.10
DENN domain containing 5B
chr1_-_182391783 0.13 ENST00000331872.11
ENST00000339526.8
glutamate-ammonia ligase
chr1_-_183653307 0.11 ENST00000308641.6
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr15_-_49046427 0.11 ENST00000261847.7
ENST00000559471.6
ENST00000380927.6
ENST00000559424.1
SECIS binding protein 2 like
chr1_+_65264694 0.10 ENST00000263441.11
ENST00000395325.7
DnaJ heat shock protein family (Hsp40) member C6
chr6_+_108559742 0.10 ENST00000343882.10
forkhead box O3
chrX_-_119693150 0.10 ENST00000394610.7
septin 6
chr8_-_66613208 0.10 ENST00000522677.8
MYB proto-oncogene like 1
chr2_-_40452046 0.09 ENST00000406785.6
solute carrier family 8 member A1
chr20_-_33686371 0.09 ENST00000343380.6
E2F transcription factor 1
chr4_-_98658582 0.09 ENST00000305798.8
tetraspanin 5
chr7_-_139777986 0.08 ENST00000406875.8
homeodomain interacting protein kinase 2
chr15_+_63189554 0.08 ENST00000559006.1
ENST00000321437.9
RAB8B, member RAS oncogene family
chrX_-_13938618 0.08 ENST00000454189.6
glycoprotein M6B
chr5_-_132777344 0.08 ENST00000378706.5
septin 8
chr5_-_59893718 0.08 ENST00000340635.11
phosphodiesterase 4D
chr3_+_172750682 0.07 ENST00000232458.9
ENST00000540509.5
epithelial cell transforming 2
chrX_-_34657274 0.07 ENST00000275954.4
transmembrane protein 47
chr8_-_90646074 0.07 ENST00000458549.7
transmembrane protein 64
chr1_-_109426410 0.07 ENST00000271308.9
proteasome 20S subunit alpha 5
chrX_+_57592011 0.06 ENST00000374888.3
zinc finger X-linked duplicated B
chr19_-_31349408 0.06 ENST00000240587.5
teashirt zinc finger homeobox 3
chr3_+_152299392 0.06 ENST00000498502.5
ENST00000545754.5
ENST00000357472.7
ENST00000324196.9
muscleblind like splicing regulator 1
chr8_+_80485641 0.06 ENST00000430430.5
zinc finger and BTB domain containing 10
chr21_+_42974510 0.06 ENST00000432907.6
ENST00000291547.10
PBX/knotted 1 homeobox 1
chr2_+_237085875 0.06 ENST00000392008.6
ENST00000409334.5
ENST00000354371.7
COP9 signalosome subunit 8
chr1_+_96721762 0.06 ENST00000675735.1
ENST00000609116.5
ENST00000674951.1
ENST00000426398.3
ENST00000370197.5
ENST00000370198.5
polypyrimidine tract binding protein 2
chr15_+_38252792 0.06 ENST00000299084.9
sprouty related EVH1 domain containing 1
chr2_-_210171402 0.06 ENST00000281772.14
KAT8 regulatory NSL complex subunit 1 like
chr7_-_105876575 0.06 ENST00000318724.8
ENST00000419735.8
ataxin 7 like 1
chr14_+_52730154 0.06 ENST00000354586.5
ENST00000442123.6
serine/threonine/tyrosine interacting protein
chr13_+_43879895 0.05 ENST00000325686.7
laccase domain containing 1
chr15_-_50765656 0.05 ENST00000261854.10
signal peptide peptidase like 2A
chr20_-_5001474 0.05 ENST00000338244.6
solute carrier family 23 member 2
chr17_-_8630713 0.05 ENST00000411957.1
ENST00000360416.8
myosin heavy chain 10
chr2_+_178480446 0.05 ENST00000234453.10
pleckstrin homology domain containing A3
chr1_+_162497805 0.05 ENST00000538489.5
ENST00000489294.2
U2AF homology motif kinase 1
chr17_+_59707636 0.05 ENST00000262291.9
ENST00000587945.1
ENST00000589823.6
ENST00000592106.5
ENST00000591315.5
vacuole membrane protein 1
chr10_+_102776237 0.04 ENST00000369889.5
WW domain binding protein 1 like
chr5_+_151771884 0.04 ENST00000627077.2
ENST00000678976.1
ENST00000677408.1
ENST00000678070.1
ENST00000678964.1
ENST00000678925.1
ENST00000394123.7
ENST00000522761.6
ENST00000676827.1
G3BP stress granule assembly factor 1
chr2_+_203328378 0.04 ENST00000430418.5
ENST00000261018.12
ENST00000295851.10
ENST00000424558.5
ENST00000417864.5
ENST00000422511.6
abl interactor 2
chr17_+_57256514 0.04 ENST00000284073.7
ENST00000674964.1
musashi RNA binding protein 2
chr19_+_34254543 0.04 ENST00000588470.5
ENST00000299505.8
ENST00000589583.5
granule associated Rac and RHOG effector 1
chr12_-_15221394 0.04 ENST00000537647.5
ENST00000256953.6
ENST00000546331.5
RAS like estrogen regulated growth inhibitor
chr11_-_73598183 0.04 ENST00000064778.8
family with sequence similarity 168 member A
chr2_+_24491860 0.04 ENST00000406961.5
ENST00000405141.5
nuclear receptor coactivator 1
chr2_+_45651650 0.04 ENST00000306156.8
protein kinase C epsilon
chr9_-_120877167 0.04 ENST00000373896.8
ENST00000312189.10
PHD finger protein 19
chr1_+_35931076 0.04 ENST00000397828.3
ENST00000373191.9
argonaute RISC catalytic component 3
chr1_-_205750167 0.04 ENST00000367142.5
nuclear casein kinase and cyclin dependent kinase substrate 1
chr10_+_114821744 0.04 ENST00000369250.7
ENST00000369246.1
ENST00000369248.9
family with sequence similarity 160 member B1
chr2_+_36355712 0.04 ENST00000280527.7
cysteine rich transmembrane BMP regulator 1
chr7_-_152435786 0.04 ENST00000682283.1
ENST00000679882.1
ENST00000452749.2
ENST00000683616.1
ENST00000262189.11
ENST00000683490.1
ENST00000681082.1
ENST00000684550.1
lysine methyltransferase 2C
chr17_-_8163522 0.04 ENST00000404970.3
vesicle associated membrane protein 2
chr6_+_68635273 0.04 ENST00000370598.6
adhesion G protein-coupled receptor B3
chr12_-_89656051 0.04 ENST00000261173.6
ATPase plasma membrane Ca2+ transporting 1
chr1_-_161309961 0.03 ENST00000533357.5
ENST00000672602.2
ENST00000526189.3
myelin protein zero
chr6_+_116571477 0.03 ENST00000487832.6
ENST00000466444.7
ENST00000518117.5
RWD domain containing 1
chr15_+_41660397 0.03 ENST00000219905.12
ENST00000566586.6
MAX dimerization protein MGA
chr3_-_169769542 0.03 ENST00000330368.3
actin related protein T3
chrX_-_57910458 0.03 ENST00000358697.6
zinc finger X-linked duplicated A
chr17_+_16415553 0.03 ENST00000338560.12
transient receptor potential cation channel subfamily V member 2
chr12_+_75480745 0.03 ENST00000266659.8
GLI pathogenesis related 1
chr22_+_40177917 0.03 ENST00000454349.7
ENST00000335727.13
trinucleotide repeat containing adaptor 6B
chrX_+_104166436 0.03 ENST00000493442.2
family with sequence similarity 199, X-linked
chr13_-_74133892 0.03 ENST00000377669.7
Kruppel like factor 12
chrX_+_70290077 0.03 ENST00000374403.4
kinesin family member 4A
chr13_+_97434154 0.03 ENST00000245304.5
RAP2A, member of RAS oncogene family
chr19_+_49877694 0.03 ENST00000221543.10
TBC1 domain family member 17
chr5_+_122845488 0.03 ENST00000513881.5
sorting nexin 24
chr18_+_74534594 0.03 ENST00000582365.1
carnosine dipeptidase 1
chr12_+_111405861 0.02 ENST00000341259.7
SH2B adaptor protein 3
chr10_+_112447198 0.02 ENST00000393077.3
ENST00000432306.5
vesicle transport through interaction with t-SNAREs 1A
chr1_+_61082553 0.02 ENST00000403491.8
ENST00000371187.7
nuclear factor I A
chrX_-_134915232 0.02 ENST00000370783.8
motile sperm domain containing 1
chr1_-_174022339 0.02 ENST00000367696.7
ring finger and CCCH-type domains 1
chr2_-_174487005 0.02 ENST00000392552.7
ENST00000295500.8
ENST00000614352.4
ENST00000392551.6
G protein-coupled receptor 155
chr9_-_14314067 0.02 ENST00000397575.7
nuclear factor I B
chr12_-_96400365 0.02 ENST00000261211.8
ENST00000543119.6
cyclin dependent kinase 17
chr4_-_174283614 0.02 ENST00000513696.1
ENST00000393674.7
ENST00000503293.5
F-box protein 8
chr14_-_93207007 0.02 ENST00000556566.1
ENST00000306954.5
GON7 subunit of KEOPS complex
chr5_-_43313403 0.02 ENST00000325110.11
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr12_-_54280087 0.02 ENST00000209875.9
chromobox 5
chr18_+_56651335 0.02 ENST00000589935.1
ENST00000254442.8
ENST00000357574.7
WD repeat domain 7
chr2_+_137964446 0.02 ENST00000280096.5
ENST00000280097.5
histamine N-methyltransferase
chr6_-_145814744 0.02 ENST00000237281.5
F-box protein 30
chr12_+_121400041 0.02 ENST00000361234.9
ENST00000613529.4
ring finger protein 34
chrX_+_77910656 0.02 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr16_+_2537997 0.02 ENST00000441549.7
ENST00000268673.11
ENST00000342085.9
ENST00000389224.7
3-phosphoinositide dependent protein kinase 1
chr17_-_4263847 0.02 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ankyrin repeat and FYVE domain containing 1
chr4_-_139177185 0.02 ENST00000394235.6
E74 like ETS transcription factor 2
chr19_+_48872412 0.02 ENST00000200453.6
protein phosphatase 1 regulatory subunit 15A
chr18_+_905103 0.02 ENST00000579794.1
adenylate cyclase activating polypeptide 1
chr13_+_32586443 0.02 ENST00000315596.15
PDS5 cohesin associated factor B
chr20_-_35411963 0.02 ENST00000349714.9
ENST00000438533.5
ENST00000359226.6
ENST00000374384.6
ENST00000374385.10
ENST00000424405.5
ENST00000397554.5
ENST00000374380.6
ubiquinol-cytochrome c reductase complex assembly factor 1
chrX_+_101550537 0.02 ENST00000372829.8
armadillo repeat containing X-linked 1
chr7_-_44885446 0.02 ENST00000395699.5
purine rich element binding protein B
chr3_+_11272413 0.02 ENST00000446450.6
ENST00000354956.9
ENST00000354449.7
ENST00000419112.5
autophagy related 7
chr16_-_20900319 0.02 ENST00000564349.5
ENST00000324344.9
ERI1 exoribonuclease family member 2
defective in cullin neddylation 1 domain containing 3
chr1_-_70205531 0.02 ENST00000370952.4
leucine rich repeat containing 40
chr9_+_37422673 0.02 ENST00000318158.11
ENST00000607784.1
glyoxylate and hydroxypyruvate reductase
chr17_-_32342132 0.02 ENST00000577809.6
ENST00000225805.8
chromosome 17 open reading frame 75
chr12_+_56521798 0.02 ENST00000262031.10
RNA binding motif single stranded interacting protein 2
chr14_+_79279403 0.02 ENST00000281127.11
neurexin 3
chr3_-_72446623 0.02 ENST00000477973.4
RING1 and YY1 binding protein
chr11_-_33869816 0.01 ENST00000395833.7
LIM domain only 2
chr2_-_69387188 0.01 ENST00000674507.1
ENST00000357308.9
glutamine--fructose-6-phosphate transaminase 1
chr8_-_73878816 0.01 ENST00000602593.6
ENST00000651945.1
ENST00000419880.7
ENST00000517608.5
ENST00000650817.1
ubiquitin conjugating enzyme E2 W
chr1_-_236281951 0.01 ENST00000354619.10
endoplasmic reticulum oxidoreductase 1 beta
chr10_+_92689946 0.01 ENST00000282728.10
hematopoietically expressed homeobox
chr7_-_15561986 0.01 ENST00000342526.8
alkylglycerol monooxygenase
chr2_+_79512993 0.01 ENST00000496558.5
ENST00000451966.5
ENST00000402739.9
ENST00000629316.2
catenin alpha 2
chr15_-_42208153 0.01 ENST00000348544.4
ENST00000318006.10
VPS39 subunit of HOPS complex
chr6_-_34392627 0.01 ENST00000607016.2
nudix hydrolase 3
chr3_-_149971109 0.01 ENST00000239940.11
profilin 2
chr1_+_117606040 0.01 ENST00000369448.4
terminal nucleotidyltransferase 5C
chrX_+_119574554 0.01 ENST00000371558.7
ENST00000630695.2
ENST00000631185.2
ubiquitin conjugating enzyme E2 A
chr11_-_95924067 0.01 ENST00000676027.1
ENST00000675489.1
ENST00000409459.5
ENST00000676261.1
ENST00000352297.11
ENST00000346299.10
ENST00000676272.1
ENST00000393223.8
ENST00000675022.1
ENST00000675362.1
ENST00000675174.1
ENST00000674989.1
ENST00000675848.1
ENST00000675652.1
ENST00000481642.6
myotubularin related protein 2
chr2_-_33599269 0.01 ENST00000431950.1
ENST00000403368.1
ENST00000238823.13
family with sequence similarity 98 member A
chr19_+_32675835 0.01 ENST00000334176.4
regulator of G protein signaling 9 binding protein
chr5_+_112861188 0.01 ENST00000503445.5
ENST00000505459.6
ENST00000282999.7
ENST00000391338.3
ENST00000515463.1
ENST00000621420.5
ENST00000445150.3
signal recognition particle 19
chr11_-_74009077 0.01 ENST00000314032.9
ENST00000426995.2
uncoupling protein 3
chr14_+_35826298 0.01 ENST00000216807.12
BRMS1 like transcriptional repressor
chr10_+_110644306 0.01 ENST00000369519.4
RNA binding motif protein 20
chr12_+_71839707 0.01 ENST00000482439.6
ENST00000550746.5
ENST00000491063.5
ENST00000319106.12
ENST00000485960.7
TBC1 domain family member 15
chr1_+_151070740 0.01 ENST00000368918.8
GA binding protein transcription factor subunit beta 2
chr10_-_119596495 0.01 ENST00000369093.6
TIA1 cytotoxic granule associated RNA binding protein like 1
chr20_-_38260725 0.01 ENST00000279024.9
ENST00000496900.2
KIAA1755
chr4_-_151226427 0.01 ENST00000304527.8
ENST00000409598.8
SH3 domain containing 19
chr10_+_76318330 0.01 ENST00000496424.2
leucine rich melanocyte differentiation associated
chr15_-_64356074 0.01 ENST00000634811.1
ENST00000303052.13
ENST00000607537.6
casein kinase 1 gamma 1
chr1_-_224434750 0.01 ENST00000414423.9
ENST00000678917.1
ENST00000678555.1
ENST00000678307.1
WD repeat domain 26
chr4_+_165327659 0.01 ENST00000507013.5
ENST00000261507.11
ENST00000393766.6
ENST00000504317.1
methylsterol monooxygenase 1
chr4_+_2469068 0.01 ENST00000541204.5
ENST00000502316.5
ENST00000507247.5
ENST00000509258.5
ENST00000314289.13
ENST00000511859.5
ring finger protein 4
chr17_+_32350132 0.01 ENST00000321233.10
ENST00000394673.6
ENST00000394670.9
ENST00000579634.5
ENST00000580759.5
ENST00000342555.10
ENST00000577908.5
ENST00000394679.9
ENST00000582165.1
zinc finger protein 207
chr3_+_30606574 0.01 ENST00000295754.10
ENST00000359013.4
transforming growth factor beta receptor 2
chrX_-_70289888 0.01 ENST00000239666.9
ENST00000374454.1
PDZ domain containing 11
chr4_-_73258785 0.01 ENST00000639793.1
ENST00000358602.9
ENST00000330838.10
ENST00000561029.1
ankyrin repeat domain 17
chr1_+_153203424 0.01 ENST00000368747.2
late cornified envelope like proline rich 1
chr2_+_222861005 0.01 ENST00000680147.1
ENST00000681009.1
ENST00000679514.1
ENST00000357430.8
acyl-CoA synthetase long chain family member 3
chr8_-_19013693 0.01 ENST00000327040.13
pleckstrin and Sec7 domain containing 3
chr5_-_115625972 0.01 ENST00000333314.3
ENST00000456936.4
TMED7-TICAM2 readthrough
transmembrane p24 trafficking protein 7
chr1_-_23980308 0.01 ENST00000374452.9
ENST00000492112.3
ENST00000343255.9
ENST00000344989.10
serine and arginine rich splicing factor 10
chr11_-_62805429 0.01 ENST00000294172.7
ENST00000531131.1
ENST00000530875.5
ENST00000531709.6
nuclear RNA export factor 1
chr8_-_42051978 0.01 ENST00000265713.8
ENST00000648335.1
ENST00000485568.5
ENST00000426524.6
ENST00000396930.4
ENST00000406337.6
lysine acetyltransferase 6A
chr13_+_28659100 0.01 ENST00000460403.1
ENST00000380842.5
proteasome maturation protein
chr2_+_190408324 0.00 ENST00000417958.5
ENST00000432036.5
ENST00000392328.6
major facilitator superfamily domain containing 6
chr6_-_28399731 0.00 ENST00000396827.3
ENST00000361028.5
ENST00000684592.1
zinc finger and SCAN domain containing 12
chr7_+_141074038 0.00 ENST00000565468.6
ENST00000610315.1
transmembrane protein 178B
chr13_-_49792675 0.00 ENST00000261667.8
karyopherin subunit alpha 3
chr6_+_154733378 0.00 ENST00000367186.7
ENST00000417268.3
ENST00000367178.8
SR-related CTD associated factor 8
chr11_-_86955385 0.00 ENST00000531380.2
frizzled class receptor 4
chr18_+_62187247 0.00 ENST00000644646.2
ENST00000256858.10
ENST00000398130.6
RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
chr1_-_205631962 0.00 ENST00000289703.8
ENST00000357992.9
ETS transcription factor ELK4
chr2_+_149330506 0.00 ENST00000334166.9
LY6/PLAUR domain containing 6
chr17_-_7479616 0.00 ENST00000380599.9
zinc finger and BTB domain containing 4
chr9_-_27005659 0.00 ENST00000380055.6
leucine rich repeat containing 19

Network of associatons between targets according to the STRING database.

First level regulatory network of GUCAGUU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008218 bioluminescence(GO:0008218)
0.1 0.2 GO:2000793 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276) cell proliferation involved in heart valve development(GO:2000793)
0.0 0.2 GO:0034699 transforming growth factor beta receptor complex assembly(GO:0007181) response to luteinizing hormone(GO:0034699)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.4 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.0 0.1 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.0 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.0 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.0 GO:0060382 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.0 0.0 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.0 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation