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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HIVEP1

Z-value: 1.95

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Transcription factors associated with HIVEP1

Gene Symbol Gene ID Gene Info
ENSG00000095951.17 HIVEP zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIVEP1hg38_v1_chr6_+_12012304_120123380.902.1e-03Click!

Activity profile of HIVEP1 motif

Sorted Z-values of HIVEP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_57767057 1.49 ENST00000228606.9
cytochrome P450 family 27 subfamily B member 1
chr1_+_43935807 1.48 ENST00000438616.3
artemin
chr1_-_242449478 1.41 ENST00000427495.5
phospholipase D family member 5
chr17_+_50532713 1.35 ENST00000503690.5
ENST00000514874.5
ENST00000268933.8
epsin 3
chr1_+_46175079 1.30 ENST00000372003.6
tetraspanin 1
chr11_+_1839452 1.20 ENST00000381906.5
troponin I2, fast skeletal type
chr1_-_209651291 1.20 ENST00000391911.5
ENST00000415782.1
laminin subunit beta 3
chr19_-_51019699 1.18 ENST00000358789.8
kallikrein related peptidase 10
chr10_+_80408485 1.17 ENST00000615554.4
ENST00000372185.5
peroxiredoxin like 2A
chr19_-_51020154 1.13 ENST00000391805.5
ENST00000599077.1
kallikrein related peptidase 10
chr19_-_51020019 1.08 ENST00000309958.7
kallikrein related peptidase 10
chr16_+_22814154 1.01 ENST00000261374.4
heparan sulfate-glucosamine 3-sulfotransferase 2
chr15_-_72197772 1.01 ENST00000309731.12
GRAM domain containing 2A
chr6_+_30882914 0.97 ENST00000509639.5
ENST00000412274.6
ENST00000507901.5
ENST00000507046.5
ENST00000437124.6
ENST00000454612.6
ENST00000396342.6
discoidin domain receptor tyrosine kinase 1
chr9_+_90801909 0.94 ENST00000375747.5
spleen associated tyrosine kinase
chr15_-_78944985 0.91 ENST00000615999.5
ENST00000677789.1
ENST00000676880.1
ENST00000677936.1
ENST00000220166.10
ENST00000677810.1
ENST00000678644.1
ENST00000677534.1
ENST00000677316.1
cathepsin H
chr9_+_90801757 0.91 ENST00000375751.8
ENST00000375754.9
spleen associated tyrosine kinase
chr7_-_22356914 0.87 ENST00000344041.10
Rap guanine nucleotide exchange factor 5
chr11_+_18266254 0.87 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr2_+_162318884 0.80 ENST00000446271.5
ENST00000429691.6
grancalcin
chr11_+_34621065 0.77 ENST00000257831.8
ETS homologous factor
chr12_-_6635938 0.77 ENST00000329858.9
lysophosphatidic acid receptor 5
chr11_-_120128831 0.76 ENST00000529044.5
tripartite motif containing 29
chr10_+_80408503 0.74 ENST00000606162.6
peroxiredoxin like 2A
chr11_+_1838970 0.73 ENST00000381911.6
troponin I2, fast skeletal type
chr3_-_69386079 0.72 ENST00000398540.8
FERM domain containing 4B
chr11_-_72781858 0.69 ENST00000537947.5
StAR related lipid transfer domain containing 10
chr12_-_52926459 0.67 ENST00000552150.5
keratin 8
chr11_-_72781833 0.66 ENST00000535054.1
ENST00000545082.5
StAR related lipid transfer domain containing 10
chr8_-_15238423 0.66 ENST00000382080.6
sarcoglycan zeta
chr15_+_90184912 0.65 ENST00000561085.1
ENST00000332496.10
semaphorin 4B
chr5_+_31639104 0.65 ENST00000438447.2
PDZ domain containing 2
chr19_-_4338786 0.64 ENST00000601482.1
ENST00000600324.5
ENST00000594605.6
signal transducing adaptor family member 2
chr2_+_64454506 0.63 ENST00000409537.2
galectin like
chr6_+_14117764 0.63 ENST00000379153.4
CD83 molecule
chr2_-_162318475 0.63 ENST00000648433.1
interferon induced with helicase C domain 1
chr3_-_125120813 0.63 ENST00000430155.6
solute carrier family 12 member 8
chr2_+_222424520 0.59 ENST00000321276.8
sphingosine-1-phosphate phosphatase 2
chrX_-_32412220 0.56 ENST00000619831.5
dystrophin
chr12_-_84912816 0.56 ENST00000680469.1
ENST00000450363.4
ENST00000681106.1
solute carrier family 6 member 15
chr16_+_3065297 0.55 ENST00000325568.9
interleukin 32
chr11_+_34621109 0.53 ENST00000450654.6
ETS homologous factor
chr13_+_36431510 0.52 ENST00000630422.2
cyclin A1
chr12_-_84912705 0.51 ENST00000679933.1
ENST00000680260.1
ENST00000551010.2
ENST00000679453.1
ENST00000681281.1
solute carrier family 6 member 15
chr19_+_44809053 0.50 ENST00000611077.5
basal cell adhesion molecule (Lutheran blood group)
chr4_+_154743993 0.50 ENST00000336356.4
lecithin retinol acyltransferase
chr12_-_84912783 0.47 ENST00000680892.1
ENST00000266682.10
ENST00000680714.1
ENST00000552192.5
solute carrier family 6 member 15
chr5_-_16508951 0.46 ENST00000682628.1
reticulophagy regulator 1
chr11_+_121576760 0.46 ENST00000532694.5
ENST00000534286.5
sortilin related receptor 1
chr5_-_16508858 0.46 ENST00000684456.1
reticulophagy regulator 1
chrX_-_117973717 0.46 ENST00000262820.7
kelch like family member 13
chrX_-_117973579 0.45 ENST00000371878.5
kelch like family member 13
chr5_-_16508812 0.45 ENST00000683414.1
reticulophagy regulator 1
chr1_+_156149657 0.44 ENST00000414683.5
semaphorin 4A
chr6_+_137867241 0.42 ENST00000612899.5
ENST00000420009.5
TNF alpha induced protein 3
chr5_-_16508990 0.42 ENST00000399793.6
reticulophagy regulator 1
chr1_-_153094521 0.42 ENST00000368750.8
small proline rich protein 2E
chr12_-_47905003 0.42 ENST00000550325.5
ENST00000546653.5
ENST00000548664.1
vitamin D receptor
chr19_+_45001430 0.42 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr5_-_16508788 0.41 ENST00000682142.1
reticulophagy regulator 1
chr19_-_42390268 0.41 ENST00000597255.1
ENST00000222032.10
cornifelin
chr3_+_98763331 0.40 ENST00000485391.5
ENST00000492254.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr12_+_6946468 0.38 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6
chr2_+_26346086 0.38 ENST00000613142.4
ENST00000260585.12
ENST00000447170.1
selenoprotein I
chr19_+_14031746 0.38 ENST00000263379.4
interleukin 27 receptor subunit alpha
chr1_+_156153568 0.37 ENST00000368284.5
ENST00000368286.6
ENST00000368285.8
ENST00000438830.5
semaphorin 4A
chr15_-_74725370 0.37 ENST00000567032.5
ENST00000564596.5
ENST00000566503.1
ENST00000395049.8
ENST00000379727.8
ENST00000617691.4
ENST00000395048.6
cytochrome P450 family 1 subfamily A member 1
chr12_-_47904986 0.36 ENST00000549336.6
vitamin D receptor
chr15_+_74615808 0.36 ENST00000395066.9
ENST00000568139.6
ENST00000563297.5
ENST00000568488.6
CDC like kinase 3
chr4_-_76023489 0.36 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr6_+_137867414 0.36 ENST00000237289.8
ENST00000433680.1
TNF alpha induced protein 3
chr1_+_212565334 0.35 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chr10_-_71773513 0.35 ENST00000394957.8
V-set immunoregulatory receptor
chr8_-_17676484 0.35 ENST00000634613.1
ENST00000519066.5
microtubule associated scaffold protein 1
chr17_-_19004727 0.34 ENST00000388995.11
family with sequence similarity 83 member G
chr6_+_116461364 0.34 ENST00000368606.7
ENST00000368605.3
calcium homeostasis modulator family member 6
chr2_-_236503688 0.34 ENST00000418802.2
ENST00000431676.6
IQ motif containing with AAA domain 1
chr17_-_40937641 0.33 ENST00000209718.8
keratin 23
chr1_+_155078829 0.33 ENST00000368408.4
ephrin A3
chr3_+_127915226 0.33 ENST00000405109.5
kelch repeat and BTB domain containing 12
chr13_-_46182136 0.33 ENST00000323076.7
lymphocyte cytosolic protein 1
chr18_+_58044343 0.32 ENST00000356462.10
ENST00000589054.5
ENST00000617539.1
ENST00000676024.1
ENST00000382850.8
ENST00000256830.13
NEDD4 like E3 ubiquitin protein ligase
chr1_+_37474572 0.32 ENST00000373087.7
zinc finger CCCH-type containing 12A
chr14_-_35404650 0.32 ENST00000553342.1
ENST00000557140.5
ENST00000216797.10
NFKB inhibitor alpha
chr3_-_112133218 0.32 ENST00000488580.5
ENST00000308910.9
ENST00000460387.6
ENST00000484193.5
ENST00000487901.1
germinal center associated signaling and motility
chr2_-_74553934 0.32 ENST00000264094.8
ENST00000393937.6
ENST00000409986.5
lysyl oxidase like 3
chr4_-_80073170 0.31 ENST00000403729.7
ANTXR cell adhesion molecule 2
chr19_+_35000275 0.30 ENST00000317991.10
ENST00000680623.1
GRAM domain containing 1A
chr5_+_151212117 0.30 ENST00000523466.5
GM2 ganglioside activator
chr10_+_132397168 0.30 ENST00000631148.2
ENST00000305233.6
PWWP domain containing 2B
chr19_+_34994778 0.30 ENST00000599564.5
GRAM domain containing 1A
chr18_-_55321640 0.30 ENST00000637169.2
transcription factor 4
chr4_-_80072993 0.30 ENST00000681115.1
ANTXR cell adhesion molecule 2
chr2_+_60881515 0.30 ENST00000295025.12
REL proto-oncogene, NF-kB subunit
chrX_-_101407893 0.30 ENST00000676156.1
ENST00000675592.1
ENST00000674634.2
ENST00000649178.1
ENST00000218516.4
galactosidase alpha
chr17_+_59220446 0.29 ENST00000284116.9
ENST00000581140.5
ENST00000581276.5
glycerophosphodiester phosphodiesterase domain containing 1
chr6_-_44265541 0.29 ENST00000619360.6
NFKB inhibitor epsilon
chr5_+_136058849 0.29 ENST00000508076.5
transforming growth factor beta induced
chr4_-_80073057 0.29 ENST00000681710.1
ANTXR cell adhesion molecule 2
chr17_-_40937445 0.28 ENST00000436344.7
ENST00000485751.1
keratin 23
chr14_-_21536928 0.28 ENST00000613414.4
spalt like transcription factor 2
chr10_+_127907036 0.28 ENST00000254667.8
ENST00000442830.5
protein tyrosine phosphatase receptor type E
chr7_-_99144053 0.27 ENST00000361125.1
ENST00000361368.7
SMAD specific E3 ubiquitin protein ligase 1
chr10_-_119165542 0.27 ENST00000419372.5
ENST00000369131.8
ENST00000355697.7
sideroflexin 4
chr2_-_162318613 0.26 ENST00000649979.2
ENST00000421365.2
interferon induced with helicase C domain 1
chr2_+_60881553 0.26 ENST00000394479.4
REL proto-oncogene, NF-kB subunit
chr6_+_29723340 0.26 ENST00000334668.8
major histocompatibility complex, class I, F
chr1_+_156147350 0.26 ENST00000435124.5
ENST00000633494.1
semaphorin 4A
chr6_+_128883114 0.26 ENST00000421865.3
ENST00000618192.4
ENST00000617695.4
laminin subunit alpha 2
chr15_-_89679360 0.26 ENST00000300055.10
perilipin 1
chr22_-_37984534 0.25 ENST00000396884.8
SRY-box transcription factor 10
chr15_-_89679411 0.25 ENST00000430628.2
perilipin 1
chr16_+_50696999 0.25 ENST00000300589.6
nucleotide binding oligomerization domain containing 2
chr21_+_43169008 0.25 ENST00000291554.6
crystallin alpha A
chr5_+_142771119 0.25 ENST00000642734.1
Rho GTPase activating protein 26
chr6_-_10694533 0.24 ENST00000460742.6
ENST00000379586.5
ENST00000259983.8
chromosome 6 open reading frame 52
chr5_+_141199555 0.24 ENST00000624887.1
ENST00000354757.5
protocadherin beta 11
chr11_-_104968533 0.24 ENST00000444739.7
caspase 4
chr19_-_55370455 0.24 ENST00000264563.7
ENST00000585513.1
ENST00000590625.5
interleukin 11
chr1_+_14945775 0.23 ENST00000400797.3
kazrin, periplakin interacting protein
chr6_+_29723421 0.23 ENST00000259951.12
ENST00000434407.6
major histocompatibility complex, class I, F
chr1_+_111227699 0.23 ENST00000369748.9
chitinase 3 like 2
chr16_-_11587450 0.23 ENST00000571688.5
lipopolysaccharide induced TNF factor
chr1_+_111227610 0.22 ENST00000369744.6
chitinase 3 like 2
chr1_-_155990062 0.22 ENST00000462460.6
Rho/Rac guanine nucleotide exchange factor 2
chr17_-_50866347 0.22 ENST00000499247.3
transducer of ERBB2, 1
chr4_-_80072563 0.22 ENST00000307333.7
ENST00000346652.10
ENST00000680913.1
ANTXR cell adhesion molecule 2
chr1_-_217137748 0.22 ENST00000493603.5
ENST00000366940.6
estrogen related receptor gamma
chr4_-_73998669 0.22 ENST00000296027.5
C-X-C motif chemokine ligand 5
chr15_+_90868580 0.22 ENST00000268171.8
furin, paired basic amino acid cleaving enzyme
chr2_+_201183120 0.22 ENST00000272879.9
ENST00000286186.11
ENST00000374650.7
ENST00000346817.9
ENST00000313728.11
ENST00000448480.1
caspase 10
chr3_+_119186716 0.22 ENST00000460625.1
uroplakin 1B
chr1_-_36385887 0.21 ENST00000373130.7
ENST00000373132.4
serine/threonine kinase 40
chr2_-_74526178 0.21 ENST00000393951.6
DEAQ-box RNA dependent ATPase 1
chr1_+_154321107 0.21 ENST00000484864.1
aquaporin 10
chr14_+_77181780 0.21 ENST00000298351.5
ENST00000554346.5
transmembrane protein 63C
chr3_+_52787825 0.21 ENST00000405128.3
inter-alpha-trypsin inhibitor heavy chain 1
chr3_-_119677346 0.21 ENST00000484810.5
ENST00000497116.1
ENST00000261070.7
cytochrome c oxidase copper chaperone COX17
chr5_+_148063971 0.21 ENST00000398454.5
ENST00000359874.7
ENST00000508733.5
ENST00000256084.8
serine peptidase inhibitor Kazal type 5
chr2_-_74526205 0.21 ENST00000451518.1
ENST00000404568.4
DEAQ-box RNA dependent ATPase 1
chr7_+_77696423 0.21 ENST00000334955.13
round spermatid basic protein 1 like
chr17_-_28549333 0.20 ENST00000470125.5
unc-119 lipid binding chaperone
chr1_+_154321076 0.20 ENST00000324978.8
aquaporin 10
chr6_-_31357171 0.20 ENST00000412585.7
ENST00000434333.1
major histocompatibility complex, class I, B
chr19_-_43820598 0.20 ENST00000594049.5
ENST00000414615.6
LY6/PLAUR domain containing 5
chr1_+_22007450 0.20 ENST00000400271.2
chymotrypsin like elastase 3A
chr14_+_22207502 0.20 ENST00000390461.2
T cell receptor alpha variable 34
chr7_-_111562455 0.20 ENST00000452895.5
ENST00000405709.7
ENST00000452753.1
ENST00000331762.7
inner mitochondrial membrane peptidase subunit 2
chr21_-_41953997 0.20 ENST00000380486.4
C2 calcium dependent domain containing 2
chr14_+_22304051 0.20 ENST00000390466.1
T cell receptor alpha variable 39
chr15_+_85380625 0.19 ENST00000560302.5
A-kinase anchoring protein 13
chr5_-_62403506 0.19 ENST00000680062.1
DIMT1 rRNA methyltransferase and ribosome maturation factor
chr1_-_25875669 0.19 ENST00000675840.1
progestin and adipoQ receptor family member 7
chr9_-_14722725 0.19 ENST00000380911.4
cerberus 1, DAN family BMP antagonist
chr14_+_103123452 0.18 ENST00000558056.1
ENST00000560869.6
TNF alpha induced protein 2
chr1_+_152719522 0.18 ENST00000368775.3
chromosome 1 open reading frame 68
chr1_-_36385872 0.18 ENST00000373129.7
serine/threonine kinase 40
chr1_-_93614091 0.18 ENST00000370247.7
BCAR3 adaptor protein, NSP family member
chr8_-_69834970 0.18 ENST00000260126.9
solute carrier organic anion transporter family member 5A1
chr5_+_36166556 0.18 ENST00000677886.1
S-phase kinase associated protein 2
chr14_+_23372809 0.18 ENST00000397242.2
ENST00000329715.2
interleukin 25
chr6_+_43517079 0.18 ENST00000372344.6
ENST00000642195.1
ENST00000643799.1
ENST00000304004.7
ENST00000646433.1
ENST00000607635.2
ENST00000643341.1
ENST00000423780.1
RNA polymerase I and III subunit C
chr15_+_41774459 0.18 ENST00000457542.7
ENST00000456763.6
mitogen-activated protein kinase binding protein 1
chr19_-_4831689 0.17 ENST00000248244.6
toll like receptor adaptor molecule 1
chr11_-_105023136 0.17 ENST00000526056.5
ENST00000531367.5
ENST00000456094.1
ENST00000444749.6
ENST00000393141.6
ENST00000418434.5
ENST00000260315.8
caspase 5
chr16_-_2980282 0.17 ENST00000572619.1
ENST00000574415.5
ENST00000440027.6
ENST00000572059.1
protein kinase, membrane associated tyrosine/threonine 1
chr1_+_84408230 0.17 ENST00000370662.3
deoxyribonuclease 2 beta
chr6_+_29942523 0.17 ENST00000376809.10
ENST00000376802.2
ENST00000638375.1
major histocompatibility complex, class I, A
chr2_+_232697362 0.17 ENST00000482666.5
ENST00000483164.5
ENST00000490229.5
ENST00000464805.5
ENST00000489328.1
GRB10 interacting GYF protein 2
chr1_-_46604214 0.17 ENST00000371946.9
ENST00000428112.7
ENST00000529170.6
ENST00000371945.10
MAPK interacting serine/threonine kinase 1
chr6_+_135181268 0.17 ENST00000341911.10
ENST00000442647.7
ENST00000618728.4
ENST00000316528.12
ENST00000616088.4
MYB proto-oncogene, transcription factor
chr2_+_201182873 0.16 ENST00000360132.7
caspase 10
chr1_-_46604283 0.16 ENST00000341183.9
ENST00000649800.1
ENST00000650026.1
ENST00000650508.1
ENST00000496619.6
MAPK interacting serine/threonine kinase 1
chr17_+_74274241 0.16 ENST00000582036.5
dynein axonemal intermediate chain 2
chr5_-_142698004 0.16 ENST00000407758.5
ENST00000441680.6
ENST00000419524.6
ENST00000621536.4
fibroblast growth factor 1
chr12_-_54981838 0.16 ENST00000316577.12
thymocyte expressed, positive selection associated 1
chr12_+_50057548 0.16 ENST00000228468.8
ENST00000447966.7
acid sensing ion channel subunit 1
chr16_+_56936654 0.16 ENST00000563911.5
homocysteine inducible ER protein with ubiquitin like domain 1
chr1_-_10472475 0.16 ENST00000377036.2
ENST00000377038.8
DNA fragmentation factor subunit alpha
chr3_+_6861107 0.15 ENST00000357716.9
ENST00000486284.5
ENST00000389336.8
glutamate metabotropic receptor 7
chr5_+_150640652 0.15 ENST00000307662.5
synaptopodin
chr17_-_27800524 0.15 ENST00000313735.11
nitric oxide synthase 2
chr1_+_43991588 0.15 ENST00000372318.8
coiled-coil domain containing 24
chr2_+_11612253 0.15 ENST00000396123.2
growth regulating estrogen receptor binding 1
chr4_+_154563003 0.15 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr19_-_33064872 0.15 ENST00000254260.8
rhophilin Rho GTPase binding protein 2
chr9_-_69014090 0.15 ENST00000377276.5
protein kinase cAMP-activated catalytic subunit gamma
chr9_-_111328520 0.15 ENST00000374428.1
olfactory receptor family 2 subfamily K member 2
chr6_-_31272069 0.15 ENST00000415537.1
ENST00000376228.9
ENST00000383329.7
major histocompatibility complex, class I, C
chr19_-_2042066 0.15 ENST00000591588.1
ENST00000591142.5
MAPK interacting serine/threonine kinase 2
chrX_+_37349287 0.14 ENST00000466533.5
ENST00000542554.5
ENST00000543642.5
ENST00000484460.5
ENST00000378628.9
ENST00000449135.6
ENST00000463135.1
ENST00000465127.1
proline rich and Gla domain 1
novel proline rich Gla (G-carboxyglutamic acid) 1 (PRRG1) and tetraspanin 7 (TSPAN7) protein
chr14_-_21536884 0.14 ENST00000546363.5
spalt like transcription factor 2
chr19_+_38899946 0.14 ENST00000572515.5
ENST00000313582.6
ENST00000575359.5
NFKB inhibitor beta
chr9_+_21409116 0.14 ENST00000380205.2
interferon alpha 8
chr1_+_155033824 0.14 ENST00000295542.6
ENST00000423025.6
ENST00000368419.2
DC-STAMP domain containing 1
chr14_-_24188787 0.14 ENST00000625289.1
ENST00000354464.11
importin 4
chr2_+_173354820 0.14 ENST00000347703.7
ENST00000410101.7
ENST00000410019.3
ENST00000306721.8
cell division cycle associated 7
chr11_-_75351686 0.14 ENST00000360025.7
arrestin beta 1
chr15_-_55196899 0.14 ENST00000677147.1
ENST00000260443.9
ENST00000677730.1
ribosomal L24 domain containing 1
chr16_+_74999003 0.14 ENST00000335325.9
ENST00000320619.10
zinc and ring finger 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HIVEP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.5 1.8 GO:0045401 response to molecule of fungal origin(GO:0002238) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)
0.3 1.5 GO:0061146 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.3 2.2 GO:0061709 reticulophagy(GO:0061709)
0.3 0.8 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.2 0.9 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.2 1.0 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 0.5 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 1.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.4 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.1 0.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 1.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.4 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.3 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 1.0 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.4 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.3 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.6 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.2 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.4 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.2 GO:0060585 regulation of dendritic cell cytokine production(GO:0002730) detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.2 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.2 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.2 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 0.7 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 0.2 GO:1904732 regulation of electron carrier activity(GO:1904732)
0.1 1.0 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.3 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.5 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0009624 response to nematode(GO:0009624)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 1.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.3 GO:1905245 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) regulation of aspartic-type peptidase activity(GO:1905245)
0.0 0.3 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.6 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.5 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.0 0.9 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.2 GO:0045357 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.1 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 1.0 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.0 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.1 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.0 0.3 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.5 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286) positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 1.9 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.3 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.0 0.0 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339) negative regulation of type B pancreatic cell development(GO:2000077)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.1 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.2 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.2 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.0 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.0 0.2 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.0 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.6 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0014010 Schwann cell proliferation(GO:0014010)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0009804 coumarin metabolic process(GO:0009804) flavone metabolic process(GO:0051552)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 1.4 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.1 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.4 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.2 GO:0008340 determination of adult lifespan(GO:0008340)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0019815 B cell receptor complex(GO:0019815)
0.2 1.2 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.5 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.1 0.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 1.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.9 GO:0005861 troponin complex(GO:0005861)
0.1 1.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.9 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 0.3 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0097169 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.1 0.2 GO:0097444 spine apparatus(GO:0097444)
0.0 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 1.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 2.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.6 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0097431 U5 snRNP(GO:0005682) mitotic spindle pole(GO:0097431)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1902271 D3 vitamins binding(GO:1902271)
0.3 1.5 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.2 0.5 GO:0005055 laminin receptor activity(GO:0005055)
0.2 1.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.9 GO:0031014 troponin T binding(GO:0031014)
0.1 0.4 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 1.8 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.3 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.1 0.6 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.4 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.4 GO:0015265 urea channel activity(GO:0015265)
0.1 0.4 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.5 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.1 1.7 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.9 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.2 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.1 0.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.5 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.3 GO:0016936 galactoside binding(GO:0016936)
0.1 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.2 GO:0070905 serine binding(GO:0070905)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 1.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 1.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.7 GO:0017166 vinculin binding(GO:0017166)
0.0 0.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.0 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.3 GO:0070411 activin binding(GO:0048185) I-SMAD binding(GO:0070411)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.9 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 1.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 2.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling