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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HMBOX1

Z-value: 0.86

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Transcription factors associated with HMBOX1

Gene Symbol Gene ID Gene Info
HMBOX1
ENSG00000147421.18 homeobox containing 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMBOX1hg38_v1_chr8_+_28890572_28890625,
hg38_v1_chr8_+_28891304_28891329		0.196.5e-01Click!

Activity profile of HMBOX1 motif

Sorted Z-values of HMBOX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_117425855 1.09 ENST00000368508.7
ROS1
ROS proto-oncogene 1, receptor tyrosine kinase
chr6_-_117425905 1.00 ENST00000368507.8
ROS1
ROS proto-oncogene 1, receptor tyrosine kinase
chr5_+_93583212 0.85 ENST00000327111.8
NR2F1
nuclear receptor subfamily 2 group F member 1
chr12_-_55842950 0.72 ENST00000548629.5
MMP19
matrix metallopeptidase 19
chr8_-_38468601 0.68 ENST00000341462.9
ENST00000683765.1
ENST00000356207.9
ENST00000326324.10
ENST00000335922.9
ENST00000532791.5
FGFR1
fibroblast growth factor receptor 1
chr8_-_38468627 0.67 ENST00000683815.1
ENST00000684654.1
ENST00000447712.7
ENST00000397091.9
FGFR1
fibroblast growth factor receptor 1
chr6_+_27147094 0.50 ENST00000377459.3
H2AC12
H2A clustered histone 12
chr2_-_213151590 0.47 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKZF2
IKAROS family zinc finger 2
chr9_-_70414657 0.43 ENST00000377126.4
KLF9
Kruppel like factor 9
chr17_+_50095285 0.39 ENST00000503614.5
PDK2
pyruvate dehydrogenase kinase 2
chr6_+_112087576 0.39 ENST00000368656.7
ENST00000604268.1
FAM229B
family with sequence similarity 229 member B
chr12_-_10435940 0.38 ENST00000381901.5
ENST00000381902.7
ENST00000539033.1
KLRC2
ENSG00000255641.1
killer cell lectin like receptor C2
novel protein
chr19_+_49513353 0.37 ENST00000596975.5
FCGRT
Fc fragment of IgG receptor and transporter
chr3_-_18438767 0.35 ENST00000454909.6
SATB1
SATB homeobox 1
chr13_+_23570370 0.35 ENST00000403372.6
ENST00000248484.9
TNFRSF19
TNF receptor superfamily member 19
chr20_+_43558968 0.34 ENST00000647834.1
ENST00000373100.7
ENST00000648083.1
ENST00000648530.1
SGK2
serum/glucocorticoid regulated kinase 2
chr1_-_109740304 0.33 ENST00000540225.2
GSTM3
glutathione S-transferase mu 3
chr4_-_158159657 0.33 ENST00000590648.5
GASK1B
golgi associated kinase 1B
chr2_-_2326378 0.33 ENST00000647618.1
MYT1L
myelin transcription factor 1 like
chr20_+_44582549 0.31 ENST00000372886.6
PKIG
cAMP-dependent protein kinase inhibitor gamma
chr14_+_22147988 0.31 ENST00000390457.2
TRAV27
T cell receptor alpha variable 27
chr2_-_2326210 0.30 ENST00000647755.1
MYT1L
myelin transcription factor 1 like
chr10_+_87659839 0.30 ENST00000456849.2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr9_-_92536031 0.29 ENST00000344604.9
ENST00000375540.5
ECM2
extracellular matrix protein 2
chr5_+_173889337 0.29 ENST00000520867.5
ENST00000334035.9
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr16_+_85027735 0.28 ENST00000258180.7
ENST00000538274.5
KIAA0513
KIAA0513
chr6_+_122717544 0.27 ENST00000354275.2
ENST00000368446.1
PKIB
cAMP-dependent protein kinase inhibitor beta
chr2_+_46542474 0.26 ENST00000238738.9
RHOQ
ras homolog family member Q
chr3_-_93973933 0.26 ENST00000650591.1
PROS1
protein S
chr10_+_35195843 0.26 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chrX_+_103628959 0.25 ENST00000372625.8
ENST00000372624.3
TCEAL1
transcription elongation factor A like 1
chr17_+_50095331 0.25 ENST00000503176.6
PDK2
pyruvate dehydrogenase kinase 2
chr7_+_90709231 0.25 ENST00000446790.5
ENST00000265741.7
CDK14
cyclin dependent kinase 14
chr1_+_174875505 0.24 ENST00000486220.5
RABGAP1L
RAB GTPase activating protein 1 like
chr16_-_30585497 0.23 ENST00000567773.1
ENST00000395216.3
ENST00000470110.2
ZNF785
zinc finger protein 785
chr5_+_111223905 0.23 ENST00000512453.5
CAMK4
calcium/calmodulin dependent protein kinase IV
chr2_-_86721122 0.22 ENST00000604011.5
RNF103-CHMP3
RNF103-CHMP3 readthrough
chr17_-_445939 0.22 ENST00000329099.4
RFLNB
refilin B
chr14_+_50533026 0.22 ENST00000441560.6
ATL1
atlastin GTPase 1
chr8_-_115492221 0.21 ENST00000518018.1
TRPS1
transcriptional repressor GATA binding 1
chr2_-_61854013 0.21 ENST00000404929.6
FAM161A
FAM161 centrosomal protein A
chr2_-_61854119 0.21 ENST00000405894.3
FAM161A
FAM161 centrosomal protein A
chrX_-_70289888 0.21 ENST00000239666.9
ENST00000374454.1
PDZD11
PDZ domain containing 11
chr1_-_160282458 0.21 ENST00000485079.1
ENSG00000258465.8
novel protein
chr6_+_28267355 0.21 ENST00000614088.1
ENST00000619937.4
ZSCAN26
zinc finger and SCAN domain containing 26
chr12_-_76486061 0.20 ENST00000548341.5
OSBPL8
oxysterol binding protein like 8
chr7_+_101085464 0.19 ENST00000306085.11
ENST00000412507.1
TRIM56
tripartite motif containing 56
chr17_+_44847874 0.19 ENST00000253410.3
HIGD1B
HIG1 hypoxia inducible domain family member 1B
chr6_+_28267044 0.19 ENST00000316606.10
ZSCAN26
zinc finger and SCAN domain containing 26
chr2_+_24491860 0.19 ENST00000406961.5
ENST00000405141.5
NCOA1
nuclear receptor coactivator 1
chr6_+_28267107 0.19 ENST00000621053.1
ENST00000617168.4
ENST00000421553.7
ENST00000611552.2
ENST00000623276.3
ENSG00000276302.1
ZSCAN26
novel protein
zinc finger and SCAN domain containing 26
chr5_+_141412979 0.18 ENST00000612503.1
ENST00000398610.3
PCDHGA10
protocadherin gamma subfamily A, 10
chr3_-_64268161 0.18 ENST00000564377.6
PRICKLE2
prickle planar cell polarity protein 2
chr12_+_51239278 0.18 ENST00000551313.1
DAZAP2
DAZ associated protein 2
chr12_-_4649043 0.18 ENST00000545990.6
ENST00000228850.6
AKAP3
A-kinase anchoring protein 3
chr12_-_32896757 0.17 ENST00000070846.11
ENST00000340811.9
PKP2
plakophilin 2
chr16_+_21678514 0.17 ENST00000286149.8
ENST00000388958.8
OTOA
otoancorin
chr5_+_141382702 0.17 ENST00000617050.1
ENST00000518325.2
PCDHGA7
protocadherin gamma subfamily A, 7
chr4_+_73481737 0.17 ENST00000226355.5
AFM
afamin
chr9_+_99222258 0.17 ENST00000223641.5
SEC61B
SEC61 translocon subunit beta
chr19_+_48965304 0.17 ENST00000331825.11
FTL
ferritin light chain
chr12_-_11022620 0.17 ENST00000390673.2
TAS2R19
taste 2 receptor member 19
chr17_-_3668557 0.16 ENST00000225525.4
TAX1BP3
Tax1 binding protein 3
chr10_+_122560679 0.16 ENST00000657942.1
DMBT1
deleted in malignant brain tumors 1
chr1_+_177170916 0.16 ENST00000361539.5
BRINP2
BMP/retinoic acid inducible neural specific 2
chr4_-_185956348 0.16 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
SORBS2
sorbin and SH3 domain containing 2
chr16_+_21684429 0.16 ENST00000388956.8
OTOA
otoancorin
chr1_+_27234612 0.16 ENST00000319394.8
ENST00000361771.7
WDTC1
WD and tetratricopeptide repeats 1
chr10_+_122560751 0.15 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
DMBT1
deleted in malignant brain tumors 1
chr6_-_2744126 0.15 ENST00000647417.1
MYLK4
myosin light chain kinase family member 4
chr2_+_61065863 0.15 ENST00000402291.6
KIAA1841
KIAA1841
chr12_+_120534697 0.15 ENST00000675818.1
ENST00000413266.6
ENSG00000288623.1
RNF10
novel protein
ring finger protein 10
chr6_-_15586006 0.15 ENST00000462989.6
DTNBP1
dystrobrevin binding protein 1
chr18_-_35290184 0.14 ENST00000589178.5
ENST00000592278.1
ENST00000333206.10
ENST00000592211.1
ENST00000420878.7
ENST00000610712.1
ENST00000586922.2
ZSCAN30
ENSG00000268573.1
zinc finger and SCAN domain containing 30
novel transcript
chr5_-_134632769 0.14 ENST00000505758.5
ENST00000439578.5
ENST00000502286.1
ENST00000402673.7
SAR1B
secretion associated Ras related GTPase 1B
chr7_+_134891566 0.14 ENST00000424922.5
ENST00000495522.1
CALD1
caldesmon 1
chr22_-_19431692 0.13 ENST00000340170.8
ENST00000263208.5
HIRA
histone cell cycle regulator
chr22_-_36776067 0.13 ENST00000417951.6
ENST00000433985.7
ENST00000430701.5
IFT27
intraflagellar transport 27
chr4_+_155903688 0.13 ENST00000536354.3
TDO2
tryptophan 2,3-dioxygenase
chr5_+_132369691 0.13 ENST00000245407.8
SLC22A5
solute carrier family 22 member 5
chr2_+_161231078 0.13 ENST00000439442.1
TANK
TRAF family member associated NFKB activator
chr5_+_139293939 0.13 ENST00000508689.1
ENST00000514528.5
MATR3
matrin 3
chr22_-_36776147 0.13 ENST00000340630.9
IFT27
intraflagellar transport 27
chr15_-_40038895 0.13 ENST00000558720.5
SRP14
signal recognition particle 14
chr17_+_43025203 0.13 ENST00000587250.4
RND2
Rho family GTPase 2
chr1_+_84144260 0.12 ENST00000370685.7
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr2_+_27771700 0.12 ENST00000379666.7
ENST00000296102.8
MRPL33
mitochondrial ribosomal protein L33
chrX_+_110003095 0.12 ENST00000372073.5
ENST00000372068.7
ENST00000288381.4
TMEM164
transmembrane protein 164
chr17_-_3292600 0.11 ENST00000615105.1
OR3A1
olfactory receptor family 3 subfamily A member 1
chr17_-_3668640 0.11 ENST00000611779.4
TAX1BP3
Tax1 binding protein 3
chr17_-_1492660 0.11 ENST00000648651.1
MYO1C
myosin IC
chr14_-_50532590 0.11 ENST00000013125.9
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr22_+_23857898 0.11 ENST00000316185.8
SLC2A11
solute carrier family 2 member 11
chr15_+_78873723 0.11 ENST00000559690.5
ENST00000559158.5
MORF4L1
mortality factor 4 like 1
chr11_-_47426419 0.11 ENST00000298852.8
ENST00000530912.5
ENST00000619920.4
PSMC3
proteasome 26S subunit, ATPase 3
chr4_-_139084289 0.11 ENST00000510408.5
ENST00000379549.7
ENST00000358635.7
ELF2
E74 like ETS transcription factor 2
chr11_-_125111708 0.11 ENST00000531909.5
ENST00000529530.1
TMEM218
transmembrane protein 218
chr1_+_23959797 0.11 ENST00000374468.1
ENST00000334351.8
PNRC2
proline rich nuclear receptor coactivator 2
chr4_-_151227881 0.10 ENST00000652233.1
ENST00000514152.5
SH3D19
SH3 domain containing 19
chr1_-_224434750 0.10 ENST00000414423.9
ENST00000678917.1
ENST00000678555.1
ENST00000678307.1
WDR26
WD repeat domain 26
chr19_+_49850687 0.10 ENST00000594151.5
ENST00000600603.5
ENST00000601638.5
PTOV1
PTOV1 extended AT-hook containing adaptor protein
chr2_+_219245455 0.10 ENST00000409638.7
ENST00000396738.7
ENST00000409516.7
STK16
serine/threonine kinase 16
chr11_+_65027402 0.10 ENST00000377244.8
ENST00000534637.5
ENST00000524831.5
SNX15
sorting nexin 15
chr1_-_150697128 0.10 ENST00000427665.1
ENST00000271732.8
GOLPH3L
golgi phosphoprotein 3 like
chr17_-_58531941 0.10 ENST00000581607.1
ENST00000317256.10
ENST00000426861.5
ENST00000580809.5
ENST00000577729.5
ENST00000583291.1
SEPTIN4
septin 4
chr19_+_16067526 0.09 ENST00000646974.2
TPM4
tropomyosin 4
chr17_-_59151794 0.09 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr3_+_46354072 0.09 ENST00000445132.3
ENST00000421659.1
CCR2
C-C motif chemokine receptor 2
chr1_+_236394268 0.09 ENST00000334232.9
EDARADD
EDAR associated death domain
chr1_+_151721508 0.09 ENST00000479191.2
RIIAD1
regulatory subunit of type II PKA R-subunit domain containing 1
chr7_+_134891400 0.09 ENST00000393118.6
CALD1
caldesmon 1
chr3_-_71493500 0.08 ENST00000648380.1
ENST00000650295.1
FOXP1
forkhead box P1
chr1_-_92792396 0.08 ENST00000370331.5
ENST00000540033.2
EVI5
ecotropic viral integration site 5
chr19_-_18543556 0.08 ENST00000544835.7
ENST00000608443.6
ENST00000597960.7
FKBP8
FKBP prolyl isomerase 8
chr13_-_29850605 0.08 ENST00000380680.5
UBL3
ubiquitin like 3
chr5_-_69369257 0.08 ENST00000509462.5
TAF9
TATA-box binding protein associated factor 9
chr10_-_114144599 0.08 ENST00000428953.1
CCDC186
coiled-coil domain containing 186
chrX_-_116462965 0.08 ENST00000371894.5
CT83
cancer/testis antigen 83
chr4_+_25914275 0.08 ENST00000514384.1
SMIM20
small integral membrane protein 20
chr14_-_75069478 0.08 ENST00000555463.1
ACYP1
acylphosphatase 1
chr16_-_88703611 0.08 ENST00000541206.6
RNF166
ring finger protein 166
chr3_+_38305936 0.08 ENST00000273173.4
SLC22A14
solute carrier family 22 member 14
chr1_-_110391041 0.08 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
SLC16A4
solute carrier family 16 member 4
chr14_+_34993240 0.08 ENST00000677647.1
SRP54
signal recognition particle 54
chr8_+_74320613 0.08 ENST00000675821.1
GDAP1
ganglioside induced differentiation associated protein 1
chr17_-_28576882 0.08 ENST00000395319.7
ENST00000581807.5
ENST00000226253.9
ENST00000584086.5
ENST00000395321.6
ALDOC
aldolase, fructose-bisphosphate C
chr22_-_36239517 0.07 ENST00000358502.10
ENST00000451256.6
APOL2
apolipoprotein L2
chr14_-_70416994 0.07 ENST00000621525.4
ENST00000256366.6
SYNJ2BP-COX16
SYNJ2BP
SYNJ2BP-COX16 readthrough
synaptojanin 2 binding protein
chr2_-_2326161 0.07 ENST00000649810.1
ENST00000648318.1
MYT1L
myelin transcription factor 1 like
chr6_+_31971831 0.07 ENST00000375331.7
ENST00000375333.3
STK19
serine/threonine kinase 19
chr7_+_143954844 0.07 ENST00000641412.1
OR2F1
olfactory receptor family 2 subfamily F member 1
chr4_+_25914171 0.07 ENST00000506197.2
SMIM20
small integral membrane protein 20
chr11_+_64924673 0.07 ENST00000164133.7
ENST00000532850.1
PPP2R5B
protein phosphatase 2 regulatory subunit B'beta
chrX_+_22272913 0.07 ENST00000323684.4
CBLL2
Cbl proto-oncogene like 2
chr12_+_93677556 0.07 ENST00000542893.2
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr9_+_69123009 0.07 ENST00000647986.1
TJP2
tight junction protein 2
chr1_-_152036984 0.07 ENST00000271638.3
S100A11
S100 calcium binding protein A11
chr2_-_55296361 0.07 ENST00000647547.1
CCDC88A
coiled-coil domain containing 88A
chr7_+_17299234 0.07 ENST00000637807.1
ENSG00000283321.1
novel protein
chr14_-_23286082 0.07 ENST00000357460.7
HOMEZ
homeobox and leucine zipper encoding
chr17_+_44004604 0.06 ENST00000293404.8
ENST00000589767.1
NAGS
N-acetylglutamate synthase
chr19_-_8149586 0.06 ENST00000600128.6
FBN3
fibrillin 3
chr17_-_10469558 0.06 ENST00000255381.2
MYH4
myosin heavy chain 4
chr15_-_65115185 0.06 ENST00000559089.6
UBAP1L
ubiquitin associated protein 1 like
chr8_-_94208548 0.06 ENST00000027335.8
ENST00000441892.6
ENST00000521491.1
CDH17
cadherin 17
chr19_-_58573555 0.06 ENST00000599369.5
MZF1
myeloid zinc finger 1
chr9_-_4666495 0.06 ENST00000475086.5
SPATA6L
spermatogenesis associated 6 like
chr7_+_133253064 0.06 ENST00000393161.6
ENST00000253861.5
EXOC4
exocyst complex component 4
chr19_+_47332167 0.06 ENST00000595464.3
C5AR2
complement component 5a receptor 2
chr9_-_120793377 0.06 ENST00000684001.1
ENST00000684405.1
ENST00000608872.6
FBXW2
F-box and WD repeat domain containing 2
chr5_+_177134159 0.05 ENST00000511258.5
ENST00000347982.8
NSD1
nuclear receptor binding SET domain protein 1
chr20_-_2664186 0.05 ENST00000474315.5
ENST00000380843.9
ENST00000380851.9
ENST00000613370.1
IDH3B
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta
chr6_-_31972290 0.05 ENST00000375349.7
DXO
decapping exoribonuclease
chr9_-_127950716 0.05 ENST00000373084.8
FAM102A
family with sequence similarity 102 member A
chr19_-_58573280 0.05 ENST00000594234.5
ENST00000596039.1
ENST00000215057.7
MZF1
myeloid zinc finger 1
chr14_-_50532518 0.05 ENST00000682126.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr7_+_99408958 0.05 ENST00000222969.10
BUD31
BUD31 homolog
chr11_-_31806886 0.05 ENST00000640963.1
PAX6
paired box 6
chr16_-_67247460 0.05 ENST00000258201.9
FHOD1
formin homology 2 domain containing 1
chr1_+_116111395 0.05 ENST00000684484.1
ENST00000369500.4
MAB21L3
mab-21 like 3
chr1_+_206470463 0.05 ENST00000581977.7
ENST00000578328.6
ENST00000584998.5
ENST00000579827.6
IKBKE
inhibitor of nuclear factor kappa B kinase subunit epsilon
chr14_+_67240713 0.05 ENST00000677382.1
MPP5
membrane palmitoylated protein 5
chr11_-_41459592 0.04 ENST00000528697.6
ENST00000530763.5
LRRC4C
leucine rich repeat containing 4C
chr1_-_31919093 0.04 ENST00000602683.5
ENST00000470404.5
PTP4A2
protein tyrosine phosphatase 4A2
chr4_+_118034480 0.04 ENST00000296499.6
NDST3
N-deacetylase and N-sulfotransferase 3
chr6_-_31972123 0.04 ENST00000337523.10
DXO
decapping exoribonuclease
chrX_+_71366222 0.04 ENST00000683202.1
ENST00000373790.9
TAF1
TATA-box binding protein associated factor 1
chr5_+_139293728 0.04 ENST00000510056.5
ENST00000511249.5
ENST00000394805.8
ENST00000503811.5
ENST00000618441.5
MATR3
matrin 3
chrX_+_71366290 0.04 ENST00000683782.1
ENST00000423759.6
TAF1
TATA-box binding protein associated factor 1
chr20_-_37158904 0.04 ENST00000417458.5
MROH8
maestro heat like repeat family member 8
chr11_-_31807617 0.04 ENST00000639920.1
ENST00000640460.1
PAX6
paired box 6
chr6_-_27838362 0.04 ENST00000618958.2
H2AC15
H2A clustered histone 15
chr1_-_150010675 0.04 ENST00000417191.2
ENST00000581312.6
OTUD7B
OTU deubiquitinase 7B
chr17_+_44847905 0.04 ENST00000587021.1
HIGD1B
HIG1 hypoxia inducible domain family member 1B
chr6_-_34671918 0.03 ENST00000374021.1
ILRUN
inflammation and lipid regulator with UBA-like and NBR1-like domains
chr17_-_28812224 0.03 ENST00000582059.6
FAM222B
family with sequence similarity 222 member B
chr14_+_44962177 0.03 ENST00000361462.7
ENST00000361577.7
TOGARAM1
TOG array regulator of axonemal microtubules 1
chr14_-_44961889 0.03 ENST00000579157.1
ENST00000396128.9
ENST00000556500.1
KLHL28
kelch like family member 28
chr17_-_31314066 0.03 ENST00000577894.1
EVI2B
ecotropic viral integration site 2B
chr5_-_138331770 0.03 ENST00000415130.6
ENST00000323760.11
ENST00000503022.5
CDC25C
cell division cycle 25C
chr10_-_51699559 0.03 ENST00000331173.6
CSTF2T
cleavage stimulation factor subunit 2 tau variant
chr20_-_50153637 0.03 ENST00000341698.2
ENST00000371652.9
ENST00000371650.9
PEDS1-UBE2V1
PEDS1
PEDS1-UBE2V1 readthrough
plasmanylethanolamine desaturase 1
chr4_+_186266183 0.03 ENST00000403665.7
ENST00000492972.6
ENST00000264692.8
F11
coagulation factor XI
chr3_-_121749704 0.03 ENST00000393667.7
ENST00000340645.9
ENST00000614479.4
GOLGB1
golgin B1
chr11_-_125111579 0.03 ENST00000532156.5
ENST00000532407.5
ENST00000279968.8
ENST00000527766.5
ENST00000529583.5
ENST00000524373.5
ENST00000527271.5
ENST00000526175.5
ENST00000529609.5
ENST00000682305.1
ENST00000533273.1
TMEM218
transmembrane protein 218
chr12_+_54280842 0.03 ENST00000678077.1
ENST00000548688.5
HNRNPA1
heterogeneous nuclear ribonucleoprotein A1
chr1_-_159076742 0.03 ENST00000368130.9
AIM2
absent in melanoma 2
chrX_+_136648138 0.03 ENST00000370629.7
CD40LG
CD40 ligand
chr17_+_28473635 0.03 ENST00000314669.10
ENST00000545060.2
SLC13A2
solute carrier family 13 member 2
chr6_-_27146841 0.03 ENST00000356950.2
H2BC12
H2B clustered histone 12
chr6_-_73354255 0.03 ENST00000370370.4
DPPA5
developmental pluripotency associated 5
chr11_+_117327829 0.03 ENST00000533153.5
ENST00000278935.8
ENST00000525416.5
CEP164
centrosomal protein 164
chr5_-_69369988 0.03 ENST00000380818.7
ENST00000328663.8
AK6
TAF9
adenylate kinase 6
TATA-box binding protein associated factor 9
chrX_+_71283577 0.02 ENST00000420903.6
ENST00000373856.8
ENST00000678437.1
ENST00000678830.1
ENST00000677879.1
ENST00000373841.5
ENST00000276079.13
ENST00000676797.1
ENST00000678660.1
ENST00000678231.1
ENST00000677612.1
ENST00000413858.5
ENST00000450092.6
NONO
non-POU domain containing octamer binding
chr19_-_7489003 0.02 ENST00000221480.6
PEX11G
peroxisomal biogenesis factor 11 gamma
chr14_-_89954518 0.02 ENST00000556005.1
ENST00000555872.5
EFCAB11
EF-hand calcium binding domain 11
chr7_-_120857124 0.02 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
TSPAN12
tetraspanin 12
chr20_-_56005466 0.02 ENST00000064571.3
CBLN4
cerebellin 4 precursor
chr9_+_33290493 0.02 ENST00000379540.8
ENST00000318524.6
NFX1
nuclear transcription factor, X-box binding 1
chr3_+_33114007 0.02 ENST00000320954.11
CRTAP
cartilage associated protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HMBOX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.3 2.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.4 GO:0051414 response to cortisol(GO:0051414)
0.1 0.4 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.3 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.2 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.1 0.7 GO:0001554 luteolysis(GO:0001554)
0.1 0.2 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:2000439 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.2 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.7 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.0 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.3 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.3 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0070761 PCAF complex(GO:0000125) pre-snoRNP complex(GO:0070761)
0.0 0.0 GO:0031251 PAN complex(GO:0031251)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.3 GO:0035375 zymogen binding(GO:0035375)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 1.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.3 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 2.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.0 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism