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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HMGA2

Z-value: 0.31

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Transcription factors associated with HMGA2

Gene Symbol Gene ID Gene Info
ENSG00000149948.14 high mobility group AT-hook 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMGA2hg38_v1_chr12_+_65825116_658251340.561.5e-01Click!

Activity profile of HMGA2 motif

Sorted Z-values of HMGA2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_78551733 0.40 ENST00000512884.5
ENST00000512542.5
ENST00000503570.6
ENST00000264908.11
annexin A3
chr15_+_43692886 0.38 ENST00000434505.5
ENST00000411750.5
creatine kinase, mitochondrial 1A
chr15_+_43593054 0.37 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
creatine kinase, mitochondrial 1B
chr19_-_42594918 0.16 ENST00000244336.10
CEA cell adhesion molecule 8
chr6_+_111259474 0.15 ENST00000672554.1
ENST00000673024.1
major facilitator superfamily domain containing 4B
chr6_+_111259294 0.15 ENST00000672303.1
ENST00000671876.2
ENST00000368847.5
major facilitator superfamily domain containing 4B
chr10_-_127892930 0.14 ENST00000368671.4
clarin 3
chr3_+_122055355 0.10 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chr6_+_106087580 0.09 ENST00000424894.1
ENST00000648754.1
PR/SET domain 1
chr8_+_52939182 0.07 ENST00000674939.1
neuropeptides B and W receptor 1
chr11_-_125778788 0.07 ENST00000436890.2
prostate and testis expressed 2
chr11_-_125778818 0.07 ENST00000358524.8
prostate and testis expressed 2
chr11_-_5154757 0.06 ENST00000380367.3
olfactory receptor family 52 subfamily A member 1
chr3_+_160842143 0.06 ENST00000464260.5
ENST00000295839.9
protein phosphatase, Mg2+/Mn2+ dependent 1L
chr10_-_5003850 0.05 ENST00000421196.7
ENST00000455190.2
ENST00000380753.8
aldo-keto reductase family 1 member C2
chr15_-_32403195 0.05 ENST00000512626.2
golgin A8 family member K
chrX_+_23908006 0.05 ENST00000379211.8
ENST00000648352.1
chromosome X open reading frame 58
chrX_+_118346072 0.05 ENST00000371822.9
ENST00000254029.8
ENST00000371825.7
WD repeat domain 44
chr20_-_56497608 0.04 ENST00000617620.1
glucosaminyl (N-acetyl) transferase family member 7
chr16_-_20404731 0.04 ENST00000302451.9
protein disulfide isomerase like, testis expressed
chrX_-_13319952 0.04 ENST00000622204.1
ENST00000380622.5
ataxin 3 like
chr15_+_84235773 0.04 ENST00000510439.7
ENST00000422563.6
golgin A6 family like 4
chr9_+_105700953 0.04 ENST00000374688.5
transmembrane protein 38B
chr15_+_28378664 0.04 ENST00000532622.7
ENST00000526619.6
golgin A8 family member F
chr12_+_113149708 0.04 ENST00000335621.11
cilia and flagella associated protein 73
chr12_+_69585434 0.04 ENST00000299300.11
ENST00000544368.6
chaperonin containing TCP1 subunit 2
chr10_-_60572599 0.04 ENST00000503366.5
ankyrin 3
chr20_+_56392607 0.03 ENST00000217109.9
ENST00000452950.1
cleavage stimulation factor subunit 1
chr6_-_49866453 0.03 ENST00000507853.5
cysteine rich secretory protein 1
chr1_-_247536440 0.03 ENST00000366487.4
ENST00000641802.1
olfactory receptor family 2 subfamily C member 3
chr14_-_68979314 0.03 ENST00000684713.1
ENST00000683198.1
ENST00000684598.1
ENST00000682331.1
ENST00000682291.1
ENST00000683342.1
actinin alpha 1
chr7_+_80638633 0.03 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chrX_-_77895546 0.03 ENST00000358075.11
magnesium transporter 1
chr17_-_40755328 0.03 ENST00000312150.5
keratin 25
chr10_+_94545777 0.03 ENST00000348459.10
ENST00000419900.5
ENST00000630929.2
helicase, lymphoid specific
chr19_-_10565990 0.03 ENST00000539027.5
ENST00000312962.12
ENST00000543682.3
ENST00000652042.1
ENST00000432197.5
KRI1 homolog
chr7_+_120950763 0.03 ENST00000339121.9
ENST00000315870.10
ENST00000445699.5
inhibitor of growth family member 3
chr20_-_1491407 0.03 ENST00000359801.8
signal regulatory protein beta 2
chr2_+_1413456 0.03 ENST00000539820.5
ENST00000382269.7
ENST00000345913.8
ENST00000329066.9
ENST00000382201.7
thyroid peroxidase
chr19_-_11346196 0.03 ENST00000586218.5
transmembrane protein 205
chr15_-_82349437 0.03 ENST00000621197.4
ENST00000610657.2
ENST00000619556.4
golgin A6 family like 10
chr2_-_85888685 0.03 ENST00000638178.1
ENST00000640982.1
ENST00000640992.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr8_+_33485173 0.02 ENST00000360128.11
MAK16 homolog
chr19_-_11346228 0.02 ENST00000588560.5
ENST00000592952.5
transmembrane protein 205
chr18_-_23437927 0.02 ENST00000578520.5
ENST00000383233.8
transmembrane protein 241
chr4_+_40056790 0.02 ENST00000261435.11
ENST00000515550.1
NEDD4 binding protein 2
chr20_-_33401501 0.02 ENST00000473997.5
ENST00000346416.7
ENST00000357886.8
ENST00000339269.5
CDK5 regulatory subunit associated protein 1
chr14_+_45084093 0.02 ENST00000553605.1
ENST00000355765.11
pre-mRNA processing factor 39
chr17_-_4704040 0.02 ENST00000570571.5
ENST00000575101.1
ENST00000574876.5
ENST00000572293.7
proline, glutamate and leucine rich protein 1
chr11_-_130916437 0.02 ENST00000533214.1
ENST00000528555.5
ENST00000530356.5
ENST00000265909.9
sorting nexin 19
chr4_+_183905266 0.02 ENST00000308497.9
storkhead box 2
chr19_+_41376499 0.02 ENST00000392002.7
transmembrane protein 91
chr19_-_11346259 0.02 ENST00000590788.1
ENST00000354882.10
ENST00000586590.5
ENST00000589555.5
ENST00000586956.5
ENST00000593256.6
ENST00000447337.5
ENST00000591677.5
ENST00000586701.1
ENST00000589655.1
transmembrane protein 205
RAB3D, member RAS oncogene family
chr7_-_57132425 0.02 ENST00000319636.10
zinc finger protein 479
chr2_-_54987578 0.02 ENST00000486085.5
reticulon 4
chr15_-_70702273 0.02 ENST00000558758.5
ENST00000379983.6
ENST00000560441.5
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr7_-_103344588 0.01 ENST00000426036.6
ENST00000249270.11
ENST00000379263.8
ENST00000454277.5
ENST00000412522.1
DnaJ heat shock protein family (Hsp40) member C2
chr15_-_53759634 0.01 ENST00000557913.5
ENST00000360509.10
WD repeat domain 72
chr6_-_33322803 0.01 ENST00000446511.1
ENST00000446403.1
ENST00000374542.10
ENST00000266000.10
ENST00000414083.6
ENST00000620164.4
death domain associated protein
chr2_+_169827432 0.01 ENST00000272793.11
ubiquitin protein ligase E3 component n-recognin 3
chr15_+_30604028 0.01 ENST00000566740.2
golgin A8 family member H
chr3_+_130431463 0.01 ENST00000512836.5
collagen type VI alpha 5 chain
chr2_+_171687409 0.01 ENST00000452242.5
ENST00000340296.8
dynein cytoplasmic 1 intermediate chain 2
chrX_-_154295085 0.01 ENST00000617225.4
ENST00000619903.4
testis expressed 28
chr1_+_12746192 0.01 ENST00000614859.5
chromosome 1 open reading frame 158
chr8_-_54101458 0.01 ENST00000521352.5
ENST00000618741.1
lysophospholipase 1
chr19_-_11346406 0.01 ENST00000587948.5
transmembrane protein 205
chr6_+_29585121 0.01 ENST00000641840.1
olfactory receptor family 2 subfamily H member 2
chr14_+_99481395 0.01 ENST00000389879.9
ENST00000557441.5
ENST00000555049.5
ENST00000555842.1
cyclin K
chr2_-_215393126 0.01 ENST00000456923.5
fibronectin 1
chr2_-_182522703 0.01 ENST00000410103.1
phosphodiesterase 1A
chr15_-_32455634 0.01 ENST00000509311.7
golgin A8 family member O
chr14_-_94293071 0.01 ENST00000554723.5
serpin family A member 10
chr2_-_287299 0.01 ENST00000405290.5
ALK and LTK ligand 2
chrX_-_23907887 0.01 ENST00000379226.9
apolipoprotein O
chr18_-_14132423 0.01 ENST00000589498.5
ENST00000590202.3
zinc finger protein 519
chr15_+_58410543 0.01 ENST00000356113.10
ENST00000414170.7
lipase C, hepatic type
chr1_-_21113129 0.00 ENST00000684485.1
eukaryotic translation initiation factor 4 gamma 3
chrX_+_2752024 0.00 ENST00000644266.2
ENST00000419513.7
ENST00000509484.3
ENST00000381174.10
Xg glycoprotein (Xg blood group)
chr14_-_94293024 0.00 ENST00000393096.5
serpin family A member 10
chr19_+_41376560 0.00 ENST00000436170.6
transmembrane protein 91
chr2_-_287320 0.00 ENST00000401503.5
ALK and LTK ligand 2
chr2_+_171687672 0.00 ENST00000409197.5
ENST00000456808.5
ENST00000409317.5
ENST00000409773.5
ENST00000411953.5
ENST00000409453.5
dynein cytoplasmic 1 intermediate chain 2
chr17_-_3398410 0.00 ENST00000322608.2
olfactory receptor family 1 subfamily E member 1
chr12_-_122266410 0.00 ENST00000451053.3
VPS33A core subunit of CORVET and HOPS complexes
chr19_-_11346486 0.00 ENST00000590482.5
transmembrane protein 205
chrX_-_136880715 0.00 ENST00000431446.7
ENST00000320676.11
ENST00000562646.5
RNA binding motif protein X-linked

Network of associatons between targets according to the STRING database.

First level regulatory network of HMGA2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002665 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.0 0.1 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.0 0.4 GO:0006600 creatine metabolic process(GO:0006600)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0097545 axonemal outer doublet(GO:0097545)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)