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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HNF4G

Z-value: 2.88

Motif logo

Transcription factors associated with HNF4G

Gene Symbol Gene ID Gene Info
ENSG00000164749.13 hepatocyte nuclear factor 4 gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF4Ghg38_v1_chr8_+_75539862_75539892,
hg38_v1_chr8_+_75539893_75539968
0.432.8e-01Click!

Activity profile of HNF4G motif

Sorted Z-values of HNF4G motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_41521719 3.70 ENST00000393976.6
keratin 15
chr19_-_6720641 3.00 ENST00000245907.11
complement C3
chr12_-_52452139 2.81 ENST00000252252.4
keratin 6B
chr1_-_201399525 2.05 ENST00000367313.4
ladinin 1
chr11_-_118264282 2.01 ENST00000278937.7
myelin protein zero like 2
chr8_-_56320098 1.99 ENST00000303749.8
ENST00000396721.6
short chain dehydrogenase/reductase family 16C member 5
chr18_+_36544544 1.99 ENST00000591635.5
formin homology 2 domain containing 3
chr12_-_52493250 1.96 ENST00000330722.7
keratin 6A
chr20_+_59676661 1.93 ENST00000355648.8
phosphatase and actin regulator 3
chr12_-_94616061 1.89 ENST00000551457.1
transmembrane and coiled-coil domain family 3
chr1_+_34782259 1.71 ENST00000373362.3
gap junction protein beta 3
chr1_-_201399302 1.68 ENST00000633953.1
ENST00000391967.7
ladinin 1
chr11_-_118264445 1.67 ENST00000438295.2
myelin protein zero like 2
chr11_+_394196 1.58 ENST00000331563.7
ENST00000531857.1
plakophilin 3
chr20_-_45254556 1.53 ENST00000338380.2
secretory leukocyte peptidase inhibitor
chr11_+_1838970 1.51 ENST00000381911.6
troponin I2, fast skeletal type
chr10_-_127892930 1.49 ENST00000368671.4
clarin 3
chr8_-_143878463 1.45 ENST00000615648.2
epiplakin 1
chr11_-_66729184 1.41 ENST00000533211.6
ENST00000309996.7
spectrin beta, non-erythrocytic 2
chr2_-_237590660 1.39 ENST00000409576.1
RAB17, member RAS oncogene family
chr8_-_144416819 1.31 ENST00000526658.1
ENST00000301305.8
solute carrier family 39 member 4
chr1_-_175192911 1.28 ENST00000444639.5
KIAA0040
chr8_-_144416481 1.27 ENST00000276833.9
solute carrier family 39 member 4
chr2_+_113127588 1.25 ENST00000409930.4
interleukin 1 receptor antagonist
chr11_-_119364166 1.21 ENST00000525735.1
ubiquitin specific peptidase 2
chrX_+_139530730 1.20 ENST00000218099.7
coagulation factor IX
chr1_+_160400543 1.20 ENST00000368061.3
VANGL planar cell polarity protein 2
chr4_+_99816797 1.20 ENST00000512369.2
ENST00000296414.11
dual adaptor of phosphotyrosine and 3-phosphoinositides 1
chr6_+_27247690 1.18 ENST00000421826.6
ENST00000230582.8
serine protease 16
chr12_-_56488350 1.09 ENST00000623608.3
ENST00000610413.4
glutaminase 2
chr2_-_84881039 1.07 ENST00000409520.7
TraB domain containing 2A
chr11_-_120128831 1.06 ENST00000529044.5
tripartite motif containing 29
chr2_-_237590694 1.06 ENST00000264601.8
ENST00000411462.5
ENST00000409822.1
RAB17, member RAS oncogene family
chr17_+_56593685 1.06 ENST00000332822.6
noggin
chr14_-_91867529 1.05 ENST00000435962.7
tandem C2 domains, nuclear
chr14_-_94388589 1.02 ENST00000402629.1
ENST00000556091.1
ENST00000393087.9
ENST00000554720.1
serpin family A member 1
chr1_-_209651291 1.02 ENST00000391911.5
ENST00000415782.1
laminin subunit beta 3
chr20_+_63696643 1.01 ENST00000369996.3
TNF receptor superfamily member 6b
chr16_+_3065297 0.98 ENST00000325568.9
interleukin 32
chr2_-_74440484 0.98 ENST00000305557.9
ENST00000233330.6
rhotekin
chr16_+_3065380 0.97 ENST00000551122.5
ENST00000548807.5
ENST00000528163.6
interleukin 32
chr16_+_3065311 0.96 ENST00000534507.5
ENST00000613483.4
ENST00000531965.5
ENST00000396887.7
interleukin 32
chr1_-_15585015 0.95 ENST00000375826.4
agmatinase
chr16_+_3065610 0.92 ENST00000530890.5
ENST00000444393.7
ENST00000533097.6
ENST00000008180.13
ENST00000396890.6
ENST00000525228.5
ENST00000525643.7
ENST00000548652.5
ENST00000525377.6
ENST00000530538.6
ENST00000549213.5
ENST00000552936.5
ENST00000548476.5
ENST00000552664.5
ENST00000552356.5
ENST00000551513.5
ENST00000382213.7
ENST00000548246.1
interleukin 32
chr12_+_56083308 0.92 ENST00000683164.1
ENST00000415288.6
ENST00000683018.1
erb-b2 receptor tyrosine kinase 3
chr16_+_3065348 0.90 ENST00000529699.5
ENST00000526464.6
ENST00000440815.7
ENST00000529550.5
interleukin 32
chr7_-_22357112 0.89 ENST00000405243.1
ENST00000665637.1
Rap guanine nucleotide exchange factor 5
chr2_-_31414694 0.89 ENST00000379416.4
xanthine dehydrogenase
chr2_+_162344338 0.88 ENST00000233612.8
grancalcin
chr4_-_22515932 0.87 ENST00000502482.1
adhesion G protein-coupled receptor A3
chr11_+_1834804 0.86 ENST00000341958.3
synaptotagmin 8
chr3_+_190514102 0.83 ENST00000434491.5
ENST00000422940.5
ENST00000317757.7
interleukin 1 receptor accessory protein
chr16_+_4788394 0.82 ENST00000615471.4
ENST00000589721.5
ENST00000615889.4
small integral membrane protein 22
chr1_+_26543106 0.82 ENST00000530003.5
ribosomal protein S6 kinase A1
chr1_-_40665654 0.82 ENST00000372684.8
regulating synaptic membrane exocytosis 3
chrX_+_136536099 0.81 ENST00000440515.5
ENST00000456412.1
vestigial like family member 1
chr4_-_22516001 0.81 ENST00000334304.10
adhesion G protein-coupled receptor A3
chr14_-_23154369 0.80 ENST00000453702.5
solute carrier family 7 member 8
chr11_+_1839452 0.80 ENST00000381906.5
troponin I2, fast skeletal type
chr9_-_114806031 0.76 ENST00000374045.5
TNF superfamily member 15
chr11_+_1839602 0.74 ENST00000617947.4
ENST00000252898.11
troponin I2, fast skeletal type
chr5_+_149730260 0.74 ENST00000360453.8
ENST00000394320.7
ENST00000309241.10
PPARG coactivator 1 beta
chr2_+_95274439 0.73 ENST00000317620.14
ENST00000403131.6
ENST00000317668.8
prominin 2
chr11_-_118152775 0.73 ENST00000324727.9
sodium voltage-gated channel beta subunit 4
chr16_+_57372465 0.72 ENST00000563383.1
C-X3-C motif chemokine ligand 1
chr12_+_112938284 0.72 ENST00000681346.1
2'-5'-oligoadenylate synthetase 3
chr22_+_44677044 0.71 ENST00000006251.11
proline rich 5
chr22_+_44677077 0.71 ENST00000403581.5
proline rich 5
chr9_-_115091018 0.71 ENST00000542877.5
ENST00000537320.5
ENST00000341037.8
tenascin C
chr2_+_130963642 0.70 ENST00000409303.6
Rho guanine nucleotide exchange factor 4
chr8_-_104589241 0.70 ENST00000276654.10
LDL receptor related protein 12
chr22_+_44676808 0.70 ENST00000624862.3
proline rich 5
chr11_+_67303476 0.69 ENST00000376757.9
ENST00000308298.11
slingshot protein phosphatase 3
chr11_+_67303497 0.66 ENST00000308127.9
slingshot protein phosphatase 3
chr4_-_80072993 0.66 ENST00000681115.1
ANTXR cell adhesion molecule 2
chr16_+_4788411 0.66 ENST00000589327.5
small integral membrane protein 22
chr2_+_230759918 0.65 ENST00000614925.1
calcium binding protein 39
chr17_-_4560564 0.64 ENST00000574584.1
ENST00000381550.8
ENST00000301395.7
gamma-glutamyltransferase 6
chr8_+_27491125 0.64 ENST00000517536.5
ENST00000521400.6
ENST00000521780.5
ENST00000380476.7
ENST00000518379.5
ENST00000521684.1
epoxide hydrolase 2
chr8_-_104588998 0.64 ENST00000424843.6
LDL receptor related protein 12
chr2_+_233060295 0.62 ENST00000445964.6
inositol polyphosphate-5-phosphatase D
chr16_+_2817230 0.59 ENST00000005995.8
ENST00000574813.5
serine protease 21
chr16_+_2964216 0.58 ENST00000572045.5
ENST00000571007.5
ENST00000575885.5
ENST00000303746.10
ENST00000319500.10
kringle containing transmembrane protein 2
chr19_+_6464229 0.58 ENST00000600229.6
ENST00000356762.7
crumbs cell polarity complex component 3
chr1_-_6490564 0.58 ENST00000377725.5
ENST00000340850.10
pleckstrin homology and RhoGEF domain containing G5
chr2_+_195657179 0.57 ENST00000359634.10
solute carrier family 39 member 10
chr2_+_195656734 0.57 ENST00000409086.7
solute carrier family 39 member 10
chr19_-_633500 0.56 ENST00000588649.7
RNA polymerase mitochondrial
chr19_+_48552159 0.56 ENST00000201586.7
sulfotransferase family 2B member 1
chr5_-_149063021 0.56 ENST00000515425.6
SH3 domain and tetratricopeptide repeats 2
chr11_+_1834415 0.55 ENST00000381968.7
ENST00000381978.7
synaptotagmin 8
chr3_+_190514065 0.55 ENST00000447382.6
ENST00000422625.5
ENST00000422485.5
interleukin 1 receptor accessory protein
chr1_-_43285559 0.54 ENST00000523677.6
chromosome 1 open reading frame 210
chr6_-_42142604 0.54 ENST00000356542.5
ENST00000341865.9
chromosome 6 open reading frame 132
chr3_-_116444983 0.53 ENST00000333617.8
limbic system associated membrane protein
chr3_+_141231770 0.53 ENST00000286353.9
ENST00000502783.5
ENST00000393010.6
ENST00000514680.5
2-phosphoxylose phosphatase 1
chr19_+_6464491 0.53 ENST00000308243.7
crumbs cell polarity complex component 3
chr7_+_55019032 0.52 ENST00000342916.7
ENST00000454757.6
ENST00000420316.6
epidermal growth factor receptor
chr17_+_7380534 0.51 ENST00000570896.5
tyrosine kinase non receptor 1
chr15_-_68205319 0.51 ENST00000467889.3
ENST00000448060.7
calmodulin like 4
chr17_+_7380837 0.51 ENST00000576812.5
tyrosine kinase non receptor 1
chr18_-_55586092 0.50 ENST00000563888.6
ENST00000540999.5
ENST00000627685.2
transcription factor 4
chr11_+_63369779 0.50 ENST00000279178.4
solute carrier family 22 member 9
chr18_-_55585773 0.50 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
transcription factor 4
chr13_+_25468822 0.50 ENST00000684424.1
ATPase phospholipid transporting 8A2
chr17_-_17591658 0.50 ENST00000435340.6
ENST00000255389.10
ENST00000395781.6
phosphatidylethanolamine N-methyltransferase
chr8_+_22579139 0.49 ENST00000397761.6
PDZ and LIM domain 2
chr12_-_48570046 0.49 ENST00000301046.6
ENST00000549817.1
lactalbumin alpha
chr20_+_31440626 0.49 ENST00000376309.4
defensin beta 123
chr3_-_123620496 0.48 ENST00000578202.1
myosin light chain kinase
chr1_-_6497405 0.48 ENST00000400915.8
pleckstrin homology and RhoGEF domain containing G5
chr7_-_22500152 0.47 ENST00000406890.6
ENST00000678116.1
ENST00000424363.5
STEAP family member 1B
chr2_+_147844601 0.47 ENST00000404590.1
activin A receptor type 2A
chr1_+_27342014 0.45 ENST00000618673.4
ENST00000318074.9
ENST00000616558.5
synaptotagmin like 1
chr3_-_123620571 0.45 ENST00000583087.5
myosin light chain kinase
chr21_+_42513834 0.44 ENST00000352133.3
solute carrier family 37 member 1
chr8_-_130016395 0.44 ENST00000523509.5
CYFIP related Rac1 interactor B
chr4_+_88457110 0.44 ENST00000264350.8
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr1_-_204359885 0.44 ENST00000414478.1
ENST00000272203.8
pleckstrin homology domain containing A6
chr8_+_22059342 0.44 ENST00000415253.5
dematin actin binding protein
chr17_-_19004727 0.44 ENST00000388995.11
family with sequence similarity 83 member G
chr14_-_81427390 0.42 ENST00000555447.5
stonin 2
chr18_+_58044343 0.42 ENST00000356462.10
ENST00000589054.5
ENST00000617539.1
ENST00000676024.1
ENST00000382850.8
ENST00000256830.13
NEDD4 like E3 ubiquitin protein ligase
chr19_+_7595830 0.42 ENST00000160298.9
ENST00000446248.4
calmodulin regulated spectrin associated protein family member 3
chr14_+_22497657 0.42 ENST00000390496.1
T cell receptor alpha joining 41
chr8_+_22579100 0.42 ENST00000452226.5
ENST00000397760.8
PDZ and LIM domain 2
chr9_-_33473884 0.42 ENST00000297990.9
ENST00000353159.6
ENST00000379471.3
nucleolar protein 6
chr17_-_75844334 0.42 ENST00000592386.5
ENST00000412096.6
ENST00000586147.1
ENST00000207549.9
unc-13 homolog D
chr8_+_22053543 0.42 ENST00000519850.5
ENST00000381470.7
dematin actin binding protein
chr3_+_194136138 0.41 ENST00000232424.4
hes family bHLH transcription factor 1
chr1_-_23800745 0.41 ENST00000617979.5
ENST00000418277.5
UDP-galactose-4-epimerase
chr5_-_116536458 0.41 ENST00000510263.5
semaphorin 6A
chr17_-_2711736 0.41 ENST00000651024.2
ENST00000576885.5
ENST00000574426.7
clustered mitochondria homolog
chr12_+_108880085 0.39 ENST00000228476.8
ENST00000547768.5
D-amino acid oxidase
chr1_-_59926724 0.39 ENST00000371204.4
cytochrome P450 family 2 subfamily J member 2
chr17_-_2711633 0.38 ENST00000435359.5
clustered mitochondria homolog
chr3_-_185825029 0.38 ENST00000382199.7
insulin like growth factor 2 mRNA binding protein 2
chr15_-_68205274 0.38 ENST00000540479.6
calmodulin like 4
chr4_+_70334963 0.37 ENST00000273936.6
calcium binding protein, spermatid associated 1
chr18_+_58044217 0.36 ENST00000400345.8
NEDD4 like E3 ubiquitin protein ligase
chr14_+_22202561 0.36 ENST00000390460.1
T cell receptor alpha variable 26-2
chr19_-_15379757 0.36 ENST00000680245.1
ENST00000269701.7
A-kinase anchoring protein 8
chr1_-_23484171 0.36 ENST00000336689.8
ENST00000437606.6
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr3_+_50273119 0.36 ENST00000456560.6
ENST00000418576.3
semaphorin 3B
chr17_-_27793716 0.35 ENST00000646938.1
nitric oxide synthase 2
chr3_+_50269140 0.35 ENST00000616701.5
ENST00000433753.4
ENST00000611067.4
semaphorin 3B
chr4_-_151015263 0.35 ENST00000510413.5
ENST00000507224.5
ENST00000651943.2
LPS responsive beige-like anchor protein
chr3_-_185824966 0.35 ENST00000457616.6
ENST00000346192.7
insulin like growth factor 2 mRNA binding protein 2
chr12_+_13044371 0.34 ENST00000197268.13
family with sequence similarity 234 member B
chr14_+_103121457 0.34 ENST00000333007.8
TNF alpha induced protein 2
chr4_+_143336762 0.34 ENST00000262995.8
GRB2 associated binding protein 1
chr7_+_55019010 0.33 ENST00000344576.7
ENST00000275493.7
ENST00000455089.5
epidermal growth factor receptor
chr7_+_151086466 0.33 ENST00000397238.7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr11_-_74731385 0.33 ENST00000622063.4
ENST00000376332.8
chordin like 2
chr14_-_21094488 0.33 ENST00000555270.5
zinc finger protein 219
chr1_-_23800402 0.33 ENST00000374497.7
ENST00000425913.5
UDP-galactose-4-epimerase
chr20_+_59933761 0.32 ENST00000358293.7
family with sequence similarity 217 member B
chr2_+_90038848 0.32 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr2_-_62506136 0.32 ENST00000335390.6
transmembrane protein 17
chr2_+_240452809 0.32 ENST00000420138.5
glypican 1
chrX_-_131289412 0.32 ENST00000652189.1
ENST00000651556.1
immunoglobulin superfamily member 1
chr1_+_167630093 0.32 ENST00000537350.5
ENST00000361496.3
ENST00000367854.8
RCSD domain containing 1
chr9_+_122519141 0.32 ENST00000340750.1
olfactory receptor family 1 subfamily J member 4
chr16_-_4416621 0.31 ENST00000570645.5
ENST00000574025.5
ENST00000572898.1
ENST00000537233.6
ENST00000571059.5
coronin 7
chr16_-_23557331 0.31 ENST00000563232.1
ENST00000449606.7
glutamyl-tRNA synthetase 2, mitochondrial
chr19_-_15479469 0.30 ENST00000292609.8
ENST00000340880.5
peptidoglycan recognition protein 2
chr19_+_38289138 0.30 ENST00000590738.1
ENST00000587519.4
ENST00000591889.2
serine peptidase inhibitor, Kunitz type 2
novel protein
chr17_-_82059973 0.30 ENST00000577574.5
dihydrouridine synthase 1 like
chr3_+_123067016 0.30 ENST00000316218.12
protein disulfide isomerase family A member 5
chr19_+_2163915 0.30 ENST00000398665.8
DOT1 like histone lysine methyltransferase
chr19_-_55063081 0.30 ENST00000415061.8
retinol dehydrogenase 13
chr12_+_20810698 0.30 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr6_+_155264013 0.30 ENST00000367165.3
claudin 20
chr9_-_113376973 0.29 ENST00000374180.4
haloacid dehalogenase like hydrolase domain containing 3
chr5_-_180209145 0.29 ENST00000615330.4
ENST00000361132.9
RasGEF domain family member 1C
chr16_-_4416564 0.29 ENST00000572467.5
ENST00000251166.9
ENST00000572044.1
ENST00000571052.5
CORO7-PAM16 readthrough
coronin 7
chr8_-_130016622 0.29 ENST00000518283.5
ENST00000519110.5
CYFIP related Rac1 interactor B
chr1_-_10947870 0.29 ENST00000468348.1
chromosome 1 open reading frame 127
chr16_-_11273610 0.29 ENST00000327157.4
protamine 3
chr3_-_48430045 0.29 ENST00000296440.11
plexin B1
chr1_-_1421248 0.28 ENST00000442470.1
ENST00000537107.6
ankyrin repeat domain 65
chr2_-_32011001 0.28 ENST00000404530.6
mediator of cell motility 1
chr9_-_34376878 0.28 ENST00000297625.8
myogenesis regulating glycosidase (putative)
chr12_+_6226136 0.28 ENST00000676764.1
ENST00000646407.1
CD9 molecule
chr11_-_63563370 0.28 ENST00000255695.2
phospholipase A and acyltransferase 2
chr14_-_52695543 0.28 ENST00000395686.8
endoplasmic reticulum oxidoreductase 1 alpha
chr22_+_32357867 0.28 ENST00000249007.4
ret finger protein like 3
chr3_+_32391871 0.28 ENST00000465248.1
CKLF like MARVEL transmembrane domain containing 7
chr12_-_54973683 0.28 ENST00000532804.5
ENST00000531122.5
ENST00000533446.5
thymocyte expressed, positive selection associated 1
chr20_-_45515612 0.28 ENST00000217428.7
serine peptidase inhibitor, Kunitz type 3
chr19_+_36054879 0.28 ENST00000378860.8
ENST00000427823.3
ENST00000681542.1
ENST00000680321.1
ENST00000680359.1
ENST00000680403.1
ENST00000679714.1
ENST00000679682.1
ENST00000401500.7
ENST00000680564.1
WD repeat domain 62
chr4_+_122379508 0.28 ENST00000388725.2
adenosine deaminase domain containing 1
chr8_-_144336451 0.28 ENST00000569446.3
scratch family transcriptional repressor 1
chr17_+_50346099 0.27 ENST00000017003.7
ENST00000509778.1
ENST00000507602.5
xylosyltransferase 2
chr20_-_23637933 0.27 ENST00000398411.5
cystatin C
chr19_-_40882226 0.27 ENST00000301146.9
cytochrome P450 family 2 subfamily A member 7
chr3_+_119186716 0.27 ENST00000460625.1
uroplakin 1B
chrX_-_15270031 0.27 ENST00000380483.7
ENST00000380485.7
ENST00000380488.9
ankyrin repeat and SOCS box containing 9
chr17_-_58280928 0.27 ENST00000225275.4
myeloperoxidase
chr1_-_44017296 0.27 ENST00000357730.6
ENST00000360584.6
ENST00000528803.1
solute carrier family 6 member 9

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF4G

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0001796 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.8 2.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.6 2.6 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.5 2.0 GO:0001897 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.4 1.2 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.4 1.6 GO:0002159 desmosome assembly(GO:0002159)
0.4 1.1 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.4 1.1 GO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.3 0.3 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.3 0.9 GO:0046110 xanthine metabolic process(GO:0046110)
0.3 0.9 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.3 0.8 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.2 0.7 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.2 0.7 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.2 0.7 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.2 1.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 1.0 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.2 0.6 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.2 0.6 GO:0000103 sulfate assimilation(GO:0000103)
0.2 1.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 0.5 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.2 0.6 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.2 0.9 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.2 1.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 0.6 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.4 GO:0042668 trochlear nerve development(GO:0021558) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.4 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.4 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 2.1 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.8 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.8 GO:0003011 involuntary skeletal muscle contraction(GO:0003011)
0.1 0.9 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.8 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 1.4 GO:0051547 regulation of keratinocyte migration(GO:0051547)
0.1 2.1 GO:0042574 retinal metabolic process(GO:0042574)
0.1 1.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.8 GO:0042713 sperm ejaculation(GO:0042713)
0.1 1.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.3 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.4 GO:0043335 protein unfolding(GO:0043335)
0.1 0.3 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.3 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 2.0 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.2 GO:0060309 elastin catabolic process(GO:0060309)
0.1 0.2 GO:0006113 fermentation(GO:0006113) regulation of fermentation(GO:0043465) positive regulation of skeletal muscle tissue growth(GO:0048633) regulation of NAD metabolic process(GO:1902688)
0.1 0.5 GO:0038016 insulin receptor internalization(GO:0038016)
0.1 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.2 GO:0033076 isoquinoline alkaloid metabolic process(GO:0033076)
0.1 0.2 GO:2000977 regulation of forebrain neuron differentiation(GO:2000977)
0.1 0.7 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) positive regulation of glucose mediated signaling pathway(GO:1902661)
0.1 0.2 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 2.8 GO:0007398 ectoderm development(GO:0007398)
0.1 1.2 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.3 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 1.4 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 0.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.5 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.3 GO:1904954 Spemann organizer formation(GO:0060061) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.1 0.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.2 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.7 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 0.2 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.1 0.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.5 GO:0050747 sphingomyelin biosynthetic process(GO:0006686) positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 3.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.7 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.5 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.5 GO:0015747 urate transport(GO:0015747)
0.0 0.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 3.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 1.0 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0034034 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.0 1.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086) positive regulation of transcription by glucose(GO:0046016)
0.0 0.3 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.0 0.7 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.5 GO:0043320 natural killer cell degranulation(GO:0043320)
0.0 0.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.4 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 1.4 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.9 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 3.7 GO:0070268 cornification(GO:0070268)
0.0 1.4 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.7 GO:0086027 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 0.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.2 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.3 GO:0009414 response to water deprivation(GO:0009414)
0.0 1.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.6 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.2 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.2 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 1.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0090481 UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.1 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 3.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.3 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:1901529 positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.7 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.6 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 1.2 GO:0051058 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845) retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.2 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.0 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.0 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.3 GO:0010842 retina layer formation(GO:0010842)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0060187 cell pole(GO:0060187)
0.2 0.9 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 0.7 GO:0044393 microspike(GO:0044393)
0.2 3.5 GO:0005861 troponin complex(GO:0005861)
0.1 1.0 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.7 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 2.1 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.2 GO:0034515 proteasome storage granule(GO:0034515)
0.1 2.0 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 5.8 GO:0045095 keratin filament(GO:0045095)
0.1 1.7 GO:0005922 connexon complex(GO:0005922)
0.1 1.1 GO:0008091 spectrin(GO:0008091)
0.1 0.8 GO:0005915 zonula adherens(GO:0005915)
0.1 1.8 GO:0030057 desmosome(GO:0030057)
0.1 1.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 4.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.4 GO:0001939 female pronucleus(GO:0001939)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 3.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 4.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0044307 dendritic branch(GO:0044307)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 3.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 1.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.8 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 2.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.2 3.3 GO:0031014 troponin T binding(GO:0031014)
0.2 1.6 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.2 0.9 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.7 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.2 1.1 GO:0004359 glutaminase activity(GO:0004359)
0.2 0.5 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.9 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.5 GO:0004461 lactose synthase activity(GO:0004461)
0.1 1.1 GO:0034711 inhibin binding(GO:0034711)
0.1 0.6 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.6 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.6 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 3.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.4 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 1.7 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.7 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.7 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.7 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 2.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.5 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.7 GO:0045545 syndecan binding(GO:0045545)
0.1 0.9 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 2.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.5 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.8 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.2 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.1 1.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 1.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.9 GO:0030957 Tat protein binding(GO:0030957)
0.0 9.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 1.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.0 1.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.8 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.3 GO:0005497 androgen binding(GO:0005497)
0.0 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 1.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 1.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 1.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 2.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 1.0 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.0 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 6.8 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 2.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 5.7 GO:0005125 cytokine activity(GO:0005125)
0.0 0.2 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 1.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.5 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.0 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 3.0 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 3.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.9 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 1.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 3.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 3.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 3.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 3.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels