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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOXB2_UNCX_HOXD3

Z-value: 0.44

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Transcription factors associated with HOXB2_UNCX_HOXD3

Gene Symbol Gene ID Gene Info
ENSG00000173917.11 homeobox B2
ENSG00000164853.9 UNC homeobox
ENSG00000128652.12 homeobox D3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD3hg38_v1_chr2_+_176157293_176157332-0.413.2e-01Click!
HOXB2hg38_v1_chr17_-_48545077_485451170.354.0e-01Click!

Activity profile of HOXB2_UNCX_HOXD3 motif

Sorted Z-values of HOXB2_UNCX_HOXD3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_70553638 1.07 ENST00000444975.5
ENST00000445399.5
ENST00000295400.11
ENST00000418333.6
transforming growth factor alpha
chr18_+_31447732 0.89 ENST00000257189.5
desmoglein 3
chr9_+_12693327 0.88 ENST00000388918.10
tyrosinase related protein 1
chr8_-_42377227 0.74 ENST00000220812.3
dickkopf WNT signaling pathway inhibitor 4
chr4_+_40196907 0.73 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chr3_-_151316795 0.69 ENST00000260843.5
G protein-coupled receptor 87
chr4_+_40197023 0.67 ENST00000381799.10
ras homolog family member H
chr1_-_242449478 0.66 ENST00000427495.5
phospholipase D family member 5
chr17_-_41118369 0.59 ENST00000391413.4
keratin associated protein 4-11
chr12_+_107318395 0.58 ENST00000420571.6
ENST00000280758.10
BTB domain containing 11
chr2_-_70553440 0.54 ENST00000450929.5
transforming growth factor alpha
chr18_+_63887698 0.50 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr7_+_70596078 0.48 ENST00000644506.1
activator of transcription and developmental regulator AUTS2
chr7_-_22194709 0.47 ENST00000458533.5
Rap guanine nucleotide exchange factor 5
chr12_-_27970273 0.47 ENST00000542963.1
ENST00000535992.5
parathyroid hormone like hormone
chr5_+_67004618 0.46 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr10_+_116427839 0.46 ENST00000369230.4
pancreatic lipase related protein 3
chr20_+_59835853 0.46 ENST00000492611.5
phosphatase and actin regulator 3
chr6_-_106975616 0.45 ENST00000610952.1
CD24 molecule
chr12_-_27970047 0.45 ENST00000395868.7
parathyroid hormone like hormone
chr2_+_68734773 0.44 ENST00000409202.8
Rho GTPase activating protein 25
chr5_+_36606355 0.42 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr1_+_160400543 0.42 ENST00000368061.3
VANGL planar cell polarity protein 2
chr5_-_83673544 0.42 ENST00000503117.1
ENST00000510978.5
hyaluronan and proteoglycan link protein 1
chr6_+_130018565 0.39 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr5_+_140848360 0.36 ENST00000532602.2
protocadherin alpha 9
chr11_-_124320197 0.35 ENST00000624618.2
olfactory receptor family 8 subfamily D member 2
chr9_-_5304713 0.32 ENST00000381627.4
relaxin 2
chr6_-_136526472 0.32 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr10_-_104085847 0.32 ENST00000648076.2
collagen type XVII alpha 1 chain
chr8_-_85341705 0.31 ENST00000517618.5
carbonic anhydrase 1
chr7_-_25228485 0.30 ENST00000222674.2
neuropeptide VF precursor
chr3_-_139539577 0.30 ENST00000619087.4
retinol binding protein 1
chr10_+_24208774 0.30 ENST00000376456.8
ENST00000458595.5
ENST00000376452.7
ENST00000430453.6
KIAA1217
chr5_+_140841183 0.30 ENST00000378123.4
ENST00000531613.2
protocadherin alpha 8
chr12_-_10826358 0.29 ENST00000240619.2
taste 2 receptor member 10
chr11_+_124241095 0.29 ENST00000641972.1
olfactory receptor family 8 subfamily G member 1
chr5_-_24644968 0.28 ENST00000264463.8
cadherin 10
chr12_-_39340963 0.28 ENST00000552961.5
kinesin family member 21A
chr4_-_152679984 0.28 ENST00000304385.8
ENST00000504064.1
transmembrane protein 154
chr12_+_43836043 0.27 ENST00000266534.8
ENST00000551577.5
transmembrane protein 117
chr19_-_51019699 0.27 ENST00000358789.8
kallikrein related peptidase 10
chr4_+_68447453 0.26 ENST00000305363.9
transmembrane serine protease 11E
chr12_-_84892120 0.24 ENST00000680379.1
solute carrier family 6 member 15
chrX_+_139530730 0.24 ENST00000218099.7
coagulation factor IX
chr6_-_32941018 0.24 ENST00000418107.3
major histocompatibility complex, class II, DM beta
chr19_-_3557563 0.24 ENST00000389395.7
ENST00000355415.7
major facilitator superfamily domain containing 12
chr9_+_122519141 0.24 ENST00000340750.1
olfactory receptor family 1 subfamily J member 4
chr10_+_46375645 0.24 ENST00000622769.4
annexin A8 like 1
chr6_-_136466858 0.24 ENST00000544465.5
microtubule associated protein 7
chr1_+_156284299 0.23 ENST00000456810.1
ENST00000405535.3
transmembrane protein 79
chr17_-_41149823 0.23 ENST00000343246.6
keratin associated protein 4-5
chr2_+_112095189 0.23 ENST00000649734.1
transmembrane protein 87B
chr7_-_22193824 0.23 ENST00000401957.6
Rap guanine nucleotide exchange factor 5
chr10_+_46375619 0.23 ENST00000584982.7
ENST00000613703.4
annexin A8 like 1
chr1_-_93681829 0.23 ENST00000260502.11
BCAR3 adaptor protein, NSP family member
chr21_-_40847149 0.23 ENST00000400454.6
DS cell adhesion molecule
chr3_-_112829367 0.23 ENST00000448932.4
ENST00000617549.3
CD200 receptor 1 like
chr12_+_20810698 0.22 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr10_+_11823348 0.22 ENST00000277570.10
ENST00000622831.4
proline and serine rich 2
chr4_-_142305935 0.22 ENST00000511838.5
inositol polyphosphate-4-phosphatase type II B
chr2_+_68734861 0.22 ENST00000467265.5
Rho GTPase activating protein 25
chr8_+_100158576 0.22 ENST00000388798.7
sperm associated antigen 1
chr12_+_41437680 0.21 ENST00000649474.1
ENST00000539469.6
ENST00000298919.7
PDZ domain containing ring finger 4
chr6_-_136526654 0.21 ENST00000611373.1
microtubule associated protein 7
chr4_-_142305826 0.21 ENST00000514525.1
inositol polyphosphate-4-phosphatase type II B
chr11_-_124445696 0.21 ENST00000642064.1
olfactory receptor family 8 subfamily B member 8
chr7_+_107583919 0.21 ENST00000491150.5
B cell receptor associated protein 29
chr3_+_111998739 0.21 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr19_-_51020154 0.20 ENST00000391805.5
ENST00000599077.1
kallikrein related peptidase 10
chr3_-_33645433 0.20 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr2_-_207167220 0.20 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr6_-_47042306 0.20 ENST00000371253.7
adhesion G protein-coupled receptor F1
chr8_-_41309434 0.20 ENST00000220772.8
secreted frizzled related protein 1
chr19_-_51020019 0.19 ENST00000309958.7
kallikrein related peptidase 10
chr17_-_66229380 0.19 ENST00000205948.11
apolipoprotein H
chr14_+_61187544 0.19 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
protein kinase C eta
chr4_+_76435216 0.19 ENST00000296043.7
shroom family member 3
chr12_-_51028234 0.19 ENST00000547688.7
ENST00000394904.9
solute carrier family 11 member 2
chr1_+_152908538 0.19 ENST00000368764.4
involucrin
chr3_+_130850585 0.19 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr3_-_112845950 0.18 ENST00000398214.5
CD200 receptor 1 like
chr1_-_24143112 0.18 ENST00000270800.2
interleukin 22 receptor subunit alpha 1
chr2_+_190180930 0.18 ENST00000443551.2
chromosome 2 open reading frame 88
chr5_+_90474848 0.18 ENST00000651687.1
RNA polymerase III subunit G
chr18_-_36129305 0.18 ENST00000269187.10
ENST00000590986.5
ENST00000440549.6
solute carrier family 39 member 6
chr18_-_36122110 0.18 ENST00000586829.1
solute carrier family 39 member 6
chr11_-_102780620 0.18 ENST00000279441.9
ENST00000539681.1
matrix metallopeptidase 10
chr17_-_40799939 0.18 ENST00000306658.8
keratin 28
chr5_+_90474879 0.18 ENST00000504930.5
ENST00000514483.5
RNA polymerase III subunit G
chr14_-_103715433 0.17 ENST00000554913.5
ENST00000555055.6
ENST00000554974.5
ENST00000553361.5
ENST00000555964.5
ENST00000556682.5
ENST00000553332.5
ENST00000352127.11
X-ray repair cross complementing 3
chr3_+_189631373 0.17 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chr3_+_111999326 0.17 ENST00000494932.1
transgelin 3
chr18_-_63661884 0.17 ENST00000332821.8
ENST00000283752.10
serpin family B member 3
chr14_+_22271921 0.17 ENST00000390464.2
T cell receptor alpha variable 38-1
chr6_-_132798587 0.17 ENST00000275227.9
solute carrier family 18 member B1
chr18_+_63587297 0.17 ENST00000269489.9
serpin family B member 13
chr9_+_5450503 0.17 ENST00000381573.8
ENST00000381577.4
CD274 molecule
chr21_-_41926680 0.17 ENST00000329623.11
C2 calcium dependent domain containing 2
chr6_+_132538290 0.17 ENST00000434551.2
trace amine associated receptor 9
chr6_+_130421086 0.17 ENST00000545622.5
transmembrane protein 200A
chr18_+_63587336 0.17 ENST00000344731.10
serpin family B member 13
chr11_+_59436469 0.16 ENST00000641045.1
olfactory receptor family 5 subfamily A member 1
chr11_+_35176575 0.16 ENST00000526000.6
CD44 molecule (Indian blood group)
chr1_+_27935110 0.16 ENST00000549094.1
sphingomyelin phosphodiesterase acid like 3B
chr12_-_14950606 0.16 ENST00000536592.5
Rho GDP dissociation inhibitor beta
chr3_-_69080350 0.16 ENST00000630585.1
ENST00000361055.9
ENST00000415609.6
ENST00000349511.8
ubiquitin like modifier activating enzyme 3
chr12_-_95116967 0.16 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr17_+_57096572 0.16 ENST00000539273.5
A-kinase anchoring protein 1
chr1_+_26529745 0.16 ENST00000374168.7
ENST00000374166.8
ribosomal protein S6 kinase A1
chr1_-_92486916 0.16 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr13_-_85799400 0.16 ENST00000647374.2
SLIT and NTRK like family member 6
chr18_+_74148508 0.16 ENST00000580087.5
ENST00000169551.11
translocase of inner mitochondrial membrane 21
chr2_+_196713117 0.16 ENST00000409270.5
coiled-coil domain containing 150
chrX_-_18672101 0.16 ENST00000379984.4
retinoschisin 1
chr6_+_150721073 0.15 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chr3_-_108529322 0.15 ENST00000273353.4
myosin heavy chain 15
chr7_+_18496162 0.15 ENST00000406072.5
histone deacetylase 9
chr6_-_136526177 0.15 ENST00000617204.4
microtubule associated protein 7
chr6_-_32838727 0.15 ENST00000652259.1
ENST00000374897.4
ENST00000620123.4
ENST00000452392.2
transporter 2, ATP binding cassette subfamily B member
novel protein, TAP2-HLA-DOB readthrough
chr6_+_125219804 0.15 ENST00000524679.1
TPD52 like 1
chr8_+_32721823 0.15 ENST00000539990.3
ENST00000519240.5
neuregulin 1
chr5_-_1882902 0.15 ENST00000231357.7
iroquois homeobox 4
chr1_+_186828941 0.15 ENST00000367466.4
phospholipase A2 group IVA
chr14_-_23183641 0.15 ENST00000469263.5
ENST00000525062.1
ENST00000316902.12
ENST00000524758.1
solute carrier family 7 member 8
chr5_+_140786136 0.14 ENST00000378133.4
ENST00000504120.4
protocadherin alpha 1
chr7_-_33062750 0.14 ENST00000610140.7
5'-nucleotidase, cytosolic IIIA
chr12_+_8822610 0.14 ENST00000299698.12
alpha-2-macroglobulin like 1
chr22_-_32464440 0.14 ENST00000397450.2
ENST00000397452.5
ENST00000300399.8
BPI fold containing family C
chr11_-_129192198 0.14 ENST00000310343.13
Rho GTPase activating protein 32
chr6_+_54846735 0.14 ENST00000306858.8
family with sequence similarity 83 member B
chrX_-_115017569 0.14 ENST00000243213.2
interleukin 13 receptor subunit alpha 2
chr18_+_31376777 0.14 ENST00000308128.9
ENST00000359747.4
desmoglein 4
chr16_+_69105636 0.14 ENST00000569188.6
hyaluronan synthase 3
chr21_+_42403874 0.14 ENST00000319294.11
ENST00000398367.1
ubiquitin associated and SH3 domain containing A
chr3_+_190615308 0.13 ENST00000412080.1
interleukin 1 receptor accessory protein
chr18_-_63644250 0.13 ENST00000341074.10
ENST00000436264.1
serpin family B member 4
chr2_+_190180835 0.13 ENST00000340623.4
chromosome 2 open reading frame 88
chr12_-_21910853 0.13 ENST00000544039.5
ATP binding cassette subfamily C member 9
chr3_-_161105399 0.13 ENST00000652593.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr1_-_99766620 0.13 ENST00000646001.2
ferric chelate reductase 1
chrX_+_106201724 0.13 ENST00000372552.1
PWWP domain containing 3B
chr8_+_49911604 0.13 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
syntrophin gamma 1
chr12_+_80716906 0.12 ENST00000228644.4
myogenic factor 5
chr19_-_50952942 0.12 ENST00000594846.1
ENST00000336334.8
kallikrein related peptidase 5
chr1_+_220094086 0.12 ENST00000366922.3
isoleucyl-tRNA synthetase 2, mitochondrial
chr7_-_93226449 0.12 ENST00000394468.7
ENST00000453812.2
HEPACAM family member 2
chr19_+_44891206 0.12 ENST00000405636.6
ENST00000252487.9
ENST00000592434.5
ENST00000589649.1
ENST00000426677.7
translocase of outer mitochondrial membrane 40
chr10_+_24449426 0.12 ENST00000307544.10
KIAA1217
chr6_+_47656436 0.12 ENST00000507065.5
ENST00000296862.5
adhesion G protein-coupled receptor F2
chr7_+_141776674 0.12 ENST00000247881.4
taste 2 receptor member 4
chrM_+_10759 0.12 ENST00000361381.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4
chr2_+_181457342 0.12 ENST00000397033.7
ENST00000233573.6
integrin subunit alpha 4
chr3_-_197573323 0.12 ENST00000358186.6
ENST00000431056.5
3-hydroxybutyrate dehydrogenase 1
chr15_+_89575492 0.12 ENST00000560985.5
TOPBP1 interacting checkpoint and replication regulator
chr1_-_183590876 0.12 ENST00000367536.5
neutrophil cytosolic factor 2
chr12_-_24902243 0.12 ENST00000538118.5
branched chain amino acid transaminase 1
chr18_+_58341038 0.12 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr3_-_143848442 0.12 ENST00000474151.1
ENST00000316549.11
solute carrier family 9 member A9
chr4_-_71784046 0.12 ENST00000513476.5
ENST00000273951.13
GC vitamin D binding protein
chr4_+_87975829 0.12 ENST00000614857.5
secreted phosphoprotein 1
chr3_+_111999189 0.12 ENST00000455401.6
transgelin 3
chr4_-_103077282 0.12 ENST00000503230.5
ENST00000503818.1
solute carrier family 9 member B2
chr11_+_121576760 0.12 ENST00000532694.5
ENST00000534286.5
sortilin related receptor 1
chr4_+_48016764 0.12 ENST00000295461.10
NIPA like domain containing 1
chr7_-_22193728 0.12 ENST00000620335.4
Rap guanine nucleotide exchange factor 5
chr17_-_41124178 0.12 ENST00000394014.2
keratin associated protein 4-12
chr1_-_10964201 0.12 ENST00000418570.6
chromosome 1 open reading frame 127
chr11_+_118077009 0.12 ENST00000616579.4
ENST00000534111.5
transmembrane serine protease 4
chr8_-_124565699 0.12 ENST00000519168.5
MTSS I-BAR domain containing 1
chr2_+_233917371 0.12 ENST00000324695.9
ENST00000433712.6
transient receptor potential cation channel subfamily M member 8
chr3_+_111998915 0.12 ENST00000478951.6
transgelin 3
chrM_+_8489 0.12 ENST00000361899.2
mitochondrially encoded ATP synthase membrane subunit 6
chr9_-_123184233 0.12 ENST00000447404.6
spermatid perinuclear RNA binding protein
chr4_-_39977836 0.12 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr19_-_14979848 0.12 ENST00000594383.2
solute carrier family 1 member 6
chr6_+_29306626 0.12 ENST00000377160.4
olfactory receptor family 14 subfamily J member 1
chr11_-_89921767 0.11 ENST00000530311.6
tripartite motif containing 49D1
chr7_+_142670734 0.11 ENST00000390398.3
T cell receptor beta variable 25-1
chr7_-_101217569 0.11 ENST00000223127.8
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
chr21_-_30881572 0.11 ENST00000332378.6
keratin associated protein 11-1
chr12_+_124993633 0.11 ENST00000341446.9
ENST00000671775.2
BRI3 binding protein
chr20_+_61599755 0.11 ENST00000543233.2
cadherin 4
chr2_-_215138603 0.11 ENST00000272895.12
ATP binding cassette subfamily A member 12
chr4_+_168092530 0.11 ENST00000359299.8
annexin A10
chr11_+_27055215 0.11 ENST00000525090.1
gamma-butyrobetaine hydroxylase 1
chr2_-_24328113 0.11 ENST00000622089.4
intersectin 2
chr4_+_87975667 0.11 ENST00000237623.11
ENST00000682655.1
ENST00000508233.6
ENST00000360804.4
ENST00000395080.8
secreted phosphoprotein 1
chr17_-_64130813 0.11 ENST00000606895.2
endoplasmic reticulum to nucleus signaling 1
chr5_+_140794832 0.11 ENST00000378132.2
ENST00000526136.2
ENST00000520672.2
protocadherin alpha 2
chr5_+_136059151 0.11 ENST00000503087.1
transforming growth factor beta induced
chr12_-_118190510 0.11 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr4_-_122621011 0.11 ENST00000611104.2
ENST00000648588.1
interleukin 21
chr8_-_133297092 0.11 ENST00000522890.5
ENST00000675983.1
ENST00000518176.5
ENST00000323851.13
ENST00000522476.5
ENST00000518066.5
ENST00000521544.5
ENST00000674605.1
ENST00000518480.5
ENST00000523892.5
N-myc downstream regulated 1
chr17_+_44708608 0.11 ENST00000393547.6
ENST00000315005.8
DBF4 zinc finger B
chrX_+_136536099 0.11 ENST00000440515.5
ENST00000456412.1
vestigial like family member 1
chr13_+_73054969 0.11 ENST00000539231.5
Kruppel like factor 5
chr11_-_36598221 0.11 ENST00000311485.8
ENST00000527033.5
ENST00000532616.1
ENST00000618712.4
recombination activating 2
chr9_+_131289685 0.11 ENST00000372264.4
phospholipid phosphatase 7 (inactive)
chr11_-_129192291 0.11 ENST00000682385.1
Rho GTPase activating protein 32

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB2_UNCX_HOXD3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 0.4 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.5 GO:0032913 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.1 0.3 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 1.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 0.8 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.2 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.2 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428)
0.1 0.2 GO:0042335 cuticle development(GO:0042335)
0.1 0.2 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.2 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.2 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.1 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.1 0.1 GO:1904440 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1 0.5 GO:2000620 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.0 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.1 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.0 0.4 GO:0061709 reticulophagy(GO:0061709)
0.0 0.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.1 GO:0075732 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.4 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.1 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.4 GO:0015820 leucine transport(GO:0015820)
0.0 0.1 GO:0016116 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0050904 diapedesis(GO:0050904)
0.0 0.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.4 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.4 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.1 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.2 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0002912 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.0 0.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0009720 detection of hormone stimulus(GO:0009720)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0060003 copper ion export(GO:0060003)
0.0 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.8 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.1 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.2 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.1 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 1.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.0 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.1 GO:0033007 negative regulation of mast cell activation involved in immune response(GO:0033007) negative regulation of mast cell degranulation(GO:0043305)
0.0 0.0 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.0 GO:0035962 response to interleukin-13(GO:0035962)
0.0 0.0 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.2 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.0 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.0 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.0 GO:1903939 regulation of TORC2 signaling(GO:1903939)
0.0 0.1 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.4 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.0 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.0 GO:2000330 positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 2.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.0 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0070055 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.0 1.5 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.0 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.4 GO:0045730 respiratory burst(GO:0045730)
0.0 0.0 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.0 0.1 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.0 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.0 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.0 GO:0035498 carnosine metabolic process(GO:0035498)
0.0 0.0 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.0 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.0 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.0 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.1 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 1.2 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0044307 dendritic branch(GO:0044307)
0.0 0.1 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.3 GO:0001772 immunological synapse(GO:0001772)
0.0 1.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.0 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.0 GO:0030849 autosome(GO:0030849)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.0 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.3 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 1.4 GO:0005549 odorant binding(GO:0005549)
0.1 0.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 1.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.4 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:1902271 D3 vitamins binding(GO:1902271)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.2 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.7 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0050211 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 1.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.0 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.1 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.2 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.0 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.0 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.0 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.0 GO:0032428 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.0 0.1 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.0 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.0 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.1 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion