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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HOXB7

Z-value: 1.11

Motif logo

Transcription factors associated with HOXB7

Gene Symbol Gene ID Gene Info
ENSG00000260027.5 homeobox B7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB7hg38_v1_chr17_-_48610971_486110230.029.6e-01Click!

Activity profile of HOXB7 motif

Sorted Z-values of HOXB7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91153149 2.28 ENST00000550758.1
decorin
chr12_-_91179355 1.51 ENST00000550563.5
ENST00000546370.5
decorin
chr12_-_91179472 1.23 ENST00000550099.5
ENST00000546391.5
decorin
chr10_+_68106109 1.05 ENST00000540630.5
ENST00000354393.6
myopalladin
chr10_+_68109433 0.83 ENST00000613327.4
ENST00000358913.10
ENST00000373675.3
myopalladin
chr5_+_93583212 0.79 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chr3_+_141386862 0.75 ENST00000513258.5
zinc finger and BTB domain containing 38
chrX_+_9463272 0.69 ENST00000407597.7
ENST00000380961.5
ENST00000424279.6
transducin beta like 1 X-linked
chr11_-_63608542 0.69 ENST00000540943.1
phospholipase A and acyltransferase 3
chr10_+_122560639 0.62 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
deleted in malignant brain tumors 1
chr16_+_15502266 0.61 ENST00000452191.6
bMERB domain containing 1
chr10_+_122560679 0.61 ENST00000657942.1
deleted in malignant brain tumors 1
chr12_+_18242955 0.58 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr10_+_122560751 0.57 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
deleted in malignant brain tumors 1
chr3_+_45886501 0.56 ENST00000395963.2
C-C motif chemokine receptor 9
chr4_-_69760596 0.55 ENST00000510821.1
sulfotransferase family 1B member 1
chr13_-_33185994 0.54 ENST00000255486.8
StAR related lipid transfer domain containing 13
chr4_-_137532452 0.53 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr5_+_141392616 0.52 ENST00000398604.3
protocadherin gamma subfamily A, 8
chr4_-_69760610 0.51 ENST00000310613.8
sulfotransferase family 1B member 1
chr2_-_199458689 0.49 ENST00000443023.5
SATB homeobox 2
chr19_+_49513353 0.47 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr4_-_117085541 0.47 ENST00000310754.5
translocation associated membrane protein 1 like 1
chr8_-_107497909 0.46 ENST00000517746.6
angiopoietin 1
chr5_-_76623391 0.46 ENST00000296641.5
ENST00000504899.1
coagulation factor II thrombin receptor like 2
chr16_+_86566821 0.45 ENST00000649859.1
forkhead box C2
chr8_-_107498041 0.45 ENST00000297450.7
angiopoietin 1
chr6_+_72216745 0.44 ENST00000517827.5
regulating synaptic membrane exocytosis 1
chr2_-_199457931 0.44 ENST00000417098.6
SATB homeobox 2
chr6_+_72216442 0.44 ENST00000425662.6
ENST00000453976.6
regulating synaptic membrane exocytosis 1
chr17_-_1229706 0.44 ENST00000574139.7
ABR activator of RhoGEF and GTPase
chr6_+_113857333 0.43 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr14_+_51489112 0.41 ENST00000356218.8
FERM domain containing 6
chr9_-_71121596 0.40 ENST00000377110.9
ENST00000377111.8
ENST00000677713.2
transient receptor potential cation channel subfamily M member 3
chr15_-_93073111 0.39 ENST00000557420.1
ENST00000542321.6
repulsive guidance molecule BMP co-receptor a
chr2_+_20447065 0.38 ENST00000272233.6
ras homolog family member B
chr3_+_141386393 0.38 ENST00000503809.5
zinc finger and BTB domain containing 38
chr11_-_70661762 0.38 ENST00000357171.7
ENST00000412252.5
ENST00000449833.6
ENST00000338508.8
SH3 and multiple ankyrin repeat domains 2
chr11_-_70662197 0.35 ENST00000409161.5
SH3 and multiple ankyrin repeat domains 2
chr11_-_89490715 0.35 ENST00000528341.5
NADPH oxidase 4
chr7_-_27102669 0.33 ENST00000222718.7
homeobox A2
chr13_+_32031706 0.32 ENST00000542859.6
FRY microtubule binding protein
chr7_-_138679045 0.32 ENST00000419765.4
SVOP like
chr3_-_93973933 0.31 ENST00000650591.1
protein S
chr3_-_15797930 0.30 ENST00000683139.1
ankyrin repeat domain 28
chr20_+_37903104 0.29 ENST00000373459.4
ENST00000373461.9
ENST00000448944.1
V-set and transmembrane domain containing 2 like
chr3_+_141387616 0.28 ENST00000509883.5
zinc finger and BTB domain containing 38
chr12_+_21526287 0.27 ENST00000256969.7
spexin hormone
chr1_-_241357171 0.27 ENST00000440928.6
regulator of G protein signaling 7
chr3_-_93973833 0.27 ENST00000348974.5
ENST00000647936.1
ENST00000394236.9
ENST00000407433.6
protein S
chr1_-_241357225 0.26 ENST00000366565.5
regulator of G protein signaling 7
chr1_+_218345326 0.25 ENST00000366930.9
transforming growth factor beta 2
chr16_-_66549839 0.24 ENST00000527800.6
ENST00000677555.1
ENST00000563369.6
thymidine kinase 2
chr3_+_111674654 0.23 ENST00000636933.1
ENST00000393934.7
ENST00000477665.2
phosphatidylinositol specific phospholipase C X domain containing 2
chrX_+_57592011 0.23 ENST00000374888.3
zinc finger X-linked duplicated B
chr15_-_37101205 0.23 ENST00000338564.9
ENST00000558313.5
ENST00000340545.9
Meis homeobox 2
chr16_-_66550091 0.23 ENST00000564917.5
ENST00000677420.1
thymidine kinase 2
chr5_+_173889337 0.23 ENST00000520867.5
ENST00000334035.9
cytoplasmic polyadenylation element binding protein 4
chr9_-_70414657 0.22 ENST00000377126.4
Kruppel like factor 9
chr19_+_926001 0.22 ENST00000263620.8
AT-rich interaction domain 3A
chr1_-_103696209 0.22 ENST00000330330.10
amylase alpha 1B
chr1_+_103617427 0.22 ENST00000423678.2
ENST00000414303.7
amylase alpha 2A
chr10_+_13100075 0.22 ENST00000378747.8
ENST00000378757.6
ENST00000378752.7
ENST00000378748.7
optineurin
chr12_-_91111460 0.21 ENST00000266718.5
lumican
chr16_-_88663065 0.21 ENST00000301012.8
ENST00000569177.5
mevalonate diphosphate decarboxylase
chr16_-_66550005 0.20 ENST00000527284.6
thymidine kinase 2
chr14_-_73950393 0.20 ENST00000651776.1
FAM161 centrosomal protein B
chr5_-_139198358 0.20 ENST00000394817.7
SIL1 nucleotide exchange factor
chr1_+_103750406 0.20 ENST00000370079.3
amylase alpha 1C
chr5_+_141338753 0.20 ENST00000528330.2
ENST00000394576.3
protocadherin gamma subfamily A, 2
chr8_+_42271289 0.20 ENST00000520810.6
ENST00000520835.7
inhibitor of nuclear factor kappa B kinase subunit beta
chr1_+_103655760 0.20 ENST00000370083.9
amylase alpha 1A
chr10_+_17228215 0.19 ENST00000544301.7
vimentin
chr19_-_52095704 0.19 ENST00000594440.6
ENST00000426391.6
zinc finger protein 841
chr16_-_66550142 0.19 ENST00000417693.8
ENST00000299697.12
ENST00000451102.7
thymidine kinase 2
chr1_-_165445220 0.18 ENST00000619224.1
retinoid X receptor gamma
chr6_+_144583198 0.18 ENST00000367526.8
utrophin
chr6_+_28267107 0.18 ENST00000621053.1
ENST00000617168.4
ENST00000421553.7
ENST00000611552.2
ENST00000623276.3
novel protein
zinc finger and SCAN domain containing 26
chr2_+_169069537 0.18 ENST00000428522.5
ENST00000450153.1
ENST00000674881.1
ENST00000421653.5
dehydrogenase/reductase 9
chr19_-_20565746 0.18 ENST00000594419.1
zinc finger protein 737
chr3_+_141387801 0.18 ENST00000514251.5
zinc finger and BTB domain containing 38
chr12_-_91179517 0.18 ENST00000551354.1
decorin
chr11_-_2140967 0.17 ENST00000381389.5
insulin like growth factor 2
chrX_+_88747225 0.17 ENST00000276127.9
ENST00000373111.5
CPX chromosome region candidate 1
chr1_-_100895132 0.17 ENST00000535414.5
exostosin like glycosyltransferase 2
chr20_+_5950931 0.17 ENST00000265187.4
ENST00000652720.1
minichromosome maintenance 8 homologous recombination repair factor
novel protein
chr1_-_165445088 0.17 ENST00000359842.10
retinoid X receptor gamma
chr9_-_83267230 0.17 ENST00000328788.5
FERM domain containing 3
chr3_+_148827800 0.17 ENST00000282957.9
ENST00000468341.1
carboxypeptidase B1
chr15_-_32455634 0.17 ENST00000509311.7
golgin A8 family member O
chr17_+_1771688 0.16 ENST00000572048.1
ENST00000573763.1
serpin family F member 1
chr16_+_22490337 0.16 ENST00000415833.6
nuclear pore complex interacting protein family member B5
chr15_+_76336755 0.16 ENST00000290759.9
ISL LIM homeobox 2
chr11_-_96389936 0.16 ENST00000680763.1
ENST00000679856.1
ENST00000643839.1
ENST00000645500.1
ENST00000530106.2
coiled-coil domain containing 82
chrX_-_93673558 0.16 ENST00000475430.2
ENST00000373079.4
nucleosome assembly protein 1 like 3
chr9_-_92404559 0.16 ENST00000262551.8
ENST00000375561.10
osteoglycin
chr8_-_115668609 0.16 ENST00000220888.9
transcriptional repressor GATA binding 1
chr5_-_139198284 0.16 ENST00000507002.5
ENST00000505830.5
ENST00000508639.5
ENST00000265195.9
SIL1 nucleotide exchange factor
chr10_+_102776237 0.16 ENST00000369889.5
WW domain binding protein 1 like
chr6_+_28267044 0.15 ENST00000316606.10
zinc finger and SCAN domain containing 26
chr13_-_109786567 0.15 ENST00000375856.5
insulin receptor substrate 2
chr9_+_101398841 0.15 ENST00000339664.7
ENST00000374861.7
ENST00000259395.4
ENST00000615466.1
zinc finger protein 189
chr15_+_85380565 0.15 ENST00000559362.5
ENST00000394518.7
A-kinase anchoring protein 13
chr16_+_86578543 0.15 ENST00000320241.5
forkhead box L1
chr14_+_19743571 0.15 ENST00000642117.2
olfactory receptor family 4 subfamily Q member 3
chr10_-_13099652 0.15 ENST00000378839.1
coiled-coil domain containing 3
chr19_-_20565769 0.15 ENST00000427401.9
zinc finger protein 737
chr1_+_103749898 0.15 ENST00000622339.5
amylase alpha 1C
chr12_+_8157034 0.14 ENST00000396570.7
zinc finger protein 705A
chr11_-_96389857 0.14 ENST00000680532.1
ENST00000681014.1
ENST00000679708.1
ENST00000645439.1
ENST00000645366.1
ENST00000680728.1
ENST00000680859.1
ENST00000679788.1
ENST00000681164.1
ENST00000646818.2
ENST00000680171.1
ENST00000679696.1
ENST00000681200.1
ENST00000679960.1
ENST00000647080.1
ENST00000646050.1
ENST00000681451.1
ENST00000644686.1
ENST00000680052.1
ENST00000679616.1
ENST00000530203.2
coiled-coil domain containing 82
chr16_-_66550112 0.14 ENST00000544898.6
ENST00000620035.5
ENST00000545043.6
thymidine kinase 2
chr8_-_115668966 0.14 ENST00000395715.8
transcriptional repressor GATA binding 1
chr3_-_58627596 0.14 ENST00000474531.5
ENST00000465970.1
family with sequence similarity 107 member A
chr12_+_51590873 0.14 ENST00000667214.1
ENST00000662684.1
ENST00000638820.1
sodium voltage-gated channel alpha subunit 8
chr16_-_51151259 0.14 ENST00000251020.9
spalt like transcription factor 1
chr11_+_96389985 0.13 ENST00000332349.5
JRK like
chr3_+_108602776 0.13 ENST00000497905.5
ENST00000463306.1
DAZ interacting zinc finger protein 3
chr12_-_102061946 0.13 ENST00000240079.11
WASH complex subunit 3
chr2_-_152098810 0.13 ENST00000636442.1
ENST00000638005.1
calcium voltage-gated channel auxiliary subunit beta 4
chr17_-_7315312 0.13 ENST00000577040.2
ENST00000389167.9
ENST00000380728.7
G protein pathway suppressor 2
chr2_-_27663594 0.13 ENST00000337768.10
ENST00000405491.5
ENST00000464789.2
ENST00000406540.5
SPT7 like, STAGA complex subunit gamma
chr22_-_17258235 0.13 ENST00000649310.1
ENST00000649746.1
adenosine deaminase 2
chr16_-_71484543 0.13 ENST00000565100.6
zinc finger protein 19
chr7_+_142111739 0.13 ENST00000550469.6
ENST00000477922.3
maltase-glucoamylase 2 (putative)
chr10_+_13099585 0.12 ENST00000378764.6
optineurin
chr15_-_37098281 0.12 ENST00000559085.5
ENST00000397624.7
Meis homeobox 2
chr15_+_30604028 0.12 ENST00000566740.2
golgin A8 family member H
chr14_+_61762405 0.12 ENST00000216294.5
small nuclear RNA activating complex polypeptide 1
chr12_-_64752871 0.12 ENST00000418919.6
glucosamine (N-acetyl)-6-sulfatase
chr2_-_27663817 0.12 ENST00000404798.6
SPT7 like, STAGA complex subunit gamma
chr15_+_53978201 0.12 ENST00000647821.1
unc-13 homolog C
chr6_-_24719146 0.12 ENST00000378119.9
chromosome 6 open reading frame 62
chr3_-_71064964 0.12 ENST00000650387.1
forkhead box P1
chr9_-_120876356 0.12 ENST00000456291.1
PHD finger protein 19
chr19_-_14835252 0.12 ENST00000641666.1
ENST00000642030.1
ENST00000642000.1
olfactory receptor family 7 subfamily C member 1
chr3_-_15798184 0.11 ENST00000624145.3
ankyrin repeat domain 28
chr2_+_44168866 0.11 ENST00000282412.9
ENST00000409432.7
ENST00000378551.6
ENST00000345249.8
protein phosphatase, Mg2+/Mn2+ dependent 1B
chr15_+_85380672 0.11 ENST00000361243.6
ENST00000560256.1
A-kinase anchoring protein 13
chr11_+_124012997 0.11 ENST00000641521.1
ENST00000641722.1
olfactory receptor family 10 subfamily G member 4
chr4_+_147617366 0.11 ENST00000508208.5
ENST00000296582.8
transmembrane protein 184C
chr20_+_1118590 0.11 ENST00000246015.8
ENST00000335877.11
proteasome inhibitor subunit 1
chr12_-_102062079 0.11 ENST00000545679.5
WASH complex subunit 3
chr6_+_45422485 0.11 ENST00000359524.7
RUNX family transcription factor 2
chr3_-_71064915 0.11 ENST00000614176.5
ENST00000485326.7
forkhead box P1
chr20_-_56497608 0.11 ENST00000617620.1
glucosaminyl (N-acetyl) transferase family member 7
chr20_+_58907981 0.11 ENST00000656419.1
GNAS complex locus
chr1_+_146949314 0.11 ENST00000617844.4
ENST00000611443.4
NBPF member 12
chr12_-_7444139 0.10 ENST00000416109.2
ENST00000313599.8
CD163 molecule like 1
chr14_+_34993240 0.10 ENST00000677647.1
signal recognition particle 54
chr3_+_160225409 0.10 ENST00000326474.5
chromosome 3 open reading frame 80
chr12_+_56007484 0.10 ENST00000262032.9
IKAROS family zinc finger 4
chr3_-_58627567 0.10 ENST00000649301.1
family with sequence similarity 107 member A
chr6_+_167291329 0.10 ENST00000366829.2
unc-93 homolog A
chr1_+_224183197 0.10 ENST00000323699.9
delta 4-desaturase, sphingolipid 1
chrX_+_135985416 0.10 ENST00000370698.7
ENST00000627534.2
ENST00000370695.8
ENST00000630721.3
ENST00000678163.1
solute carrier family 9 member A6
chr22_-_30246739 0.10 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr10_-_24706622 0.10 ENST00000680286.1
Rho GTPase activating protein 21
chr21_+_25639251 0.10 ENST00000480456.6
junctional adhesion molecule 2
chrX_-_103502853 0.10 ENST00000372633.1
RAB40A, member RAS oncogene family
chr4_-_139084289 0.09 ENST00000510408.5
ENST00000379549.7
ENST00000358635.7
E74 like ETS transcription factor 2
chr11_+_31816266 0.09 ENST00000644607.1
ENST00000646221.1
ENST00000643671.1
ENST00000643931.1
ENST00000642614.1
ENST00000642818.1
ENST00000645848.1
ENST00000506388.2
ENST00000645824.1
ENST00000532942.5
PAX6 upstream antisense RNA
novel protein
chr1_+_12464912 0.09 ENST00000543766.2
vacuolar protein sorting 13 homolog D
chr1_-_111563956 0.09 ENST00000369717.8
transmembrane and immunoglobulin domain containing 3
chr8_+_28891304 0.09 ENST00000355231.9
homeobox containing 1
chr3_+_189789672 0.09 ENST00000434928.5
tumor protein p63
chr7_+_65873068 0.09 ENST00000360768.5
vitamin K epoxide reductase complex subunit 1 like 1
chr2_-_153478753 0.09 ENST00000325926.4
reprimo, TP53 dependent G2 arrest mediator homolog
chr21_+_25639272 0.09 ENST00000400532.5
ENST00000312957.9
junctional adhesion molecule 2
chr10_+_13099440 0.09 ENST00000263036.9
optineurin
chr19_-_51417791 0.09 ENST00000353836.9
sialic acid binding Ig like lectin 10
chr5_-_139383284 0.09 ENST00000353963.7
ENST00000348729.8
solute carrier family 23 member 1
chr13_+_108269629 0.09 ENST00000430559.5
ENST00000375887.9
TNF superfamily member 13b
chr7_+_142800957 0.09 ENST00000466254.1
T cell receptor beta constant 2
chr19_+_37346283 0.09 ENST00000541583.6
zinc finger protein 875
chr2_+_161136901 0.09 ENST00000259075.6
ENST00000432002.5
TRAF family member associated NFKB activator
chr18_+_31591869 0.09 ENST00000237014.8
transthyretin
chr22_+_39960397 0.08 ENST00000424496.2
novel protein similar to translation machinery associated 7 homolog (S. cerevisiae) TMA7
chr7_+_118184156 0.08 ENST00000422760.1
ENST00000249299.7
ENST00000411938.1
LSM8 homolog, U6 small nuclear RNA associated
chr7_+_65873091 0.08 ENST00000648187.1
vitamin K epoxide reductase complex subunit 1 like 1
chr2_+_63050813 0.08 ENST00000282549.7
orthodenticle homeobox 1
chr6_-_2744126 0.08 ENST00000647417.1
myosin light chain kinase family member 4
chr3_-_165078480 0.08 ENST00000264382.8
sucrase-isomaltase
chr11_-_55936400 0.08 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr1_+_224356852 0.08 ENST00000366858.7
ENST00000366857.9
ENST00000465271.6
ENST00000366856.3
cornichon family AMPA receptor auxiliary protein 4
chr5_-_126595185 0.08 ENST00000510111.6
ENST00000635851.1
ENST00000637964.1
ENST00000413020.6
ENST00000637782.1
ENST00000409134.8
ENST00000637272.1
ENST00000636879.1
ENST00000636743.1
ENST00000636886.1
ENST00000509270.2
aldehyde dehydrogenase 7 family member A1
chr3_+_191329020 0.08 ENST00000392456.4
coiled-coil domain containing 50
chr5_-_126595237 0.08 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chrM_+_9207 0.08 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr5_-_131165272 0.07 ENST00000675491.1
ENST00000506908.2
histidine triad nucleotide binding protein 1
chr17_-_41047267 0.07 ENST00000542137.1
ENST00000391419.3
keratin associated protein 2-1
chr17_-_8867639 0.07 ENST00000619866.5
phosphoinositide-3-kinase regulatory subunit 6
chr20_+_41340780 0.07 ENST00000373257.8
lipin 3
chr19_+_34926892 0.07 ENST00000303586.11
ENST00000601142.2
ENST00000439785.5
ENST00000601540.5
ENST00000601957.5
zinc finger protein 30
chr9_-_120877026 0.07 ENST00000436309.5
PHD finger protein 19
chr1_-_53220589 0.07 ENST00000294360.5
CXXC motif containing zinc binding protein
chr3_+_40100007 0.07 ENST00000539167.2
myosin VIIA and Rab interacting protein
chr3_+_156142962 0.07 ENST00000471742.5
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr4_+_143184910 0.07 ENST00000510377.5
ENST00000307017.9
ubiquitin specific peptidase 38
chr5_-_58999885 0.07 ENST00000317118.12
phosphodiesterase 4D
chr15_+_64387828 0.07 ENST00000261884.8
thyroid hormone receptor interactor 4

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3 0.9 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.2 0.6 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 0.7 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.2 1.0 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.2 0.5 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 1.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.4 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.3 GO:0021658 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.1 1.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.4 GO:0003383 apical constriction(GO:0003383)
0.1 0.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.2 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.8 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.8 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.3 GO:1904304 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0070904 L-ascorbic acid transport(GO:0015882) dehydroascorbic acid transport(GO:0070837) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:0051414 response to cortisol(GO:0051414)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.2 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.2 GO:0071279 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279)
0.0 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.5 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0039022 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.7 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.6 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.0 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.0 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.0 0.4 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.4 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.0 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.0 GO:0090310 DNA cytosine deamination(GO:0070383) negative regulation of methylation-dependent chromatin silencing(GO:0090310) regulation of mRNA modification(GO:0090365)
0.0 0.3 GO:0050667 homocysteine metabolic process(GO:0050667)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 1.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.7 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 1.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0035375 zymogen binding(GO:0035375)
0.1 1.0 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.4 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.5 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 5.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 1.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0033300 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) dehydroascorbic acid transporter activity(GO:0033300) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.0 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)