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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HSF1

Z-value: 1.48

Motif logo

Transcription factors associated with HSF1

Gene Symbol Gene ID Gene Info
ENSG00000185122.11 heat shock transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF1hg38_v1_chr8_+_144291581_1442916170.285.0e-01Click!

Activity profile of HSF1 motif

Sorted Z-values of HSF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_59628609 2.03 ENST00000541461.5
phosphatase and actin regulator 3
chr19_-_51001138 1.57 ENST00000593490.1
kallikrein related peptidase 8
chr2_+_102008515 1.38 ENST00000441002.1
interleukin 1 receptor type 2
chr19_-_35513641 1.37 ENST00000339686.8
ENST00000447113.6
dermokine
chr19_-_50952942 1.30 ENST00000594846.1
ENST00000336334.8
kallikrein related peptidase 5
chr6_+_47698574 1.27 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr6_+_47698538 1.25 ENST00000327753.7
adhesion G protein-coupled receptor F4
chr19_-_6720641 1.18 ENST00000245907.11
complement C3
chr2_+_47369301 1.15 ENST00000263735.9
epithelial cell adhesion molecule
chr1_+_34782259 1.13 ENST00000373362.3
gap junction protein beta 3
chr18_+_23873000 1.12 ENST00000269217.11
ENST00000587184.5
laminin subunit alpha 3
chr19_+_751104 1.08 ENST00000215582.8
mitotic spindle positioning
chr19_-_51020019 1.03 ENST00000309958.7
kallikrein related peptidase 10
chr19_-_51019699 1.02 ENST00000358789.8
kallikrein related peptidase 10
chr17_-_41521719 0.97 ENST00000393976.6
keratin 15
chr19_-_51020154 0.96 ENST00000391805.5
ENST00000599077.1
kallikrein related peptidase 10
chr1_-_153390976 0.91 ENST00000368732.5
ENST00000368733.4
S100 calcium binding protein A8
chr6_-_136466858 0.90 ENST00000544465.5
microtubule associated protein 7
chr19_+_35115912 0.87 ENST00000603181.5
FXYD domain containing ion transport regulator 3
chr12_-_52517929 0.85 ENST00000548409.5
keratin 5
chr19_-_50953063 0.84 ENST00000391809.6
kallikrein related peptidase 5
chr20_+_45174894 0.82 ENST00000243924.4
peptidase inhibitor 3
chr2_-_237590660 0.80 ENST00000409576.1
RAB17, member RAS oncogene family
chr11_+_10450289 0.79 ENST00000444303.6
adenosine monophosphate deaminase 3
chr20_+_46008900 0.78 ENST00000372330.3
matrix metallopeptidase 9
chr1_+_27935110 0.76 ENST00000549094.1
sphingomyelin phosphodiesterase acid like 3B
chr4_-_52751399 0.76 ENST00000440542.1
ENST00000443173.6
endogenous retrovirus group MER34 member 1, envelope
chr1_+_27934980 0.76 ENST00000373894.8
sphingomyelin phosphodiesterase acid like 3B
chr11_-_125592448 0.75 ENST00000648911.1
fasciculation and elongation protein zeta 1
chr1_+_14929734 0.75 ENST00000376028.8
ENST00000400798.6
kazrin, periplakin interacting protein
chr1_+_152985231 0.74 ENST00000368762.1
small proline rich protein 1A
chr10_-_114684612 0.73 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr10_-_114684457 0.71 ENST00000392955.7
actin binding LIM protein 1
chr6_-_170291053 0.69 ENST00000366756.4
delta like canonical Notch ligand 1
chr1_+_43530847 0.61 ENST00000617451.4
ENST00000359947.9
ENST00000438120.5
protein tyrosine phosphatase receptor type F
chr1_+_220786853 0.58 ENST00000366910.10
mitochondrial amidoxime reducing component 1
chr17_-_41505597 0.53 ENST00000336861.7
ENST00000246635.8
ENST00000587544.5
ENST00000587435.1
keratin 13
chr2_+_85133376 0.48 ENST00000282111.4
transcription factor 7 like 1
chr1_-_205994439 0.48 ENST00000617991.4
RAB7B, member RAS oncogene family
chr16_-_75495396 0.48 ENST00000332272.9
carbohydrate sulfotransferase 6
chr17_-_76501349 0.48 ENST00000590288.1
ENST00000313080.8
ENST00000592123.5
ENST00000591255.5
ENST00000585989.5
ENST00000675367.1
ENST00000591697.5
rhomboid 5 homolog 2
chr1_-_24143112 0.48 ENST00000270800.2
interleukin 22 receptor subunit alpha 1
chr15_-_72197772 0.45 ENST00000309731.12
GRAM domain containing 2A
chr4_-_76421121 0.44 ENST00000682701.1
coiled-coil domain containing 158
chr20_+_62656359 0.44 ENST00000370507.5
solute carrier organic anion transporter family member 4A1
chr11_-_119729158 0.44 ENST00000264025.8
nectin cell adhesion molecule 1
chr17_+_56834081 0.43 ENST00000572810.1
ENST00000284061.8
diacylglycerol kinase epsilon
chr1_-_147760592 0.39 ENST00000579774.3
gap junction protein alpha 5
chr12_-_10674013 0.39 ENST00000535345.5
ENST00000542562.5
ENST00000075503.8
serine/threonine/tyrosine kinase 1
chr17_-_56833889 0.38 ENST00000397861.7
chromosome 17 open reading frame 67
chr8_-_80171106 0.38 ENST00000519303.6
tumor protein D52
chr19_+_48552159 0.37 ENST00000201586.7
sulfotransferase family 2B member 1
chr12_+_2794961 0.36 ENST00000001008.6
FKBP prolyl isomerase 4
chr1_+_27935022 0.36 ENST00000411604.5
ENST00000373888.8
sphingomyelin phosphodiesterase acid like 3B
chr15_+_75198866 0.36 ENST00000562637.1
ENST00000360639.6
chromosome 15 open reading frame 39
chr3_+_130894050 0.36 ENST00000510168.6
ATPase secretory pathway Ca2+ transporting 1
chr4_+_75556048 0.36 ENST00000616557.1
ENST00000435974.2
ENST00000311623.9
odontogenesis associated phosphoprotein
chr9_+_470291 0.35 ENST00000382303.5
KN motif and ankyrin repeat domains 1
chr19_-_17334844 0.35 ENST00000159087.7
anoctamin 8
chr11_+_59713403 0.35 ENST00000641815.1
syntaxin 3
chr6_-_32816910 0.35 ENST00000447394.1
ENST00000438763.7
major histocompatibility complex, class II, DO beta
chr8_-_80171496 0.34 ENST00000379096.9
ENST00000518937.6
tumor protein D52
chrX_-_101407893 0.34 ENST00000676156.1
ENST00000675592.1
ENST00000674634.2
ENST00000649178.1
ENST00000218516.4
galactosidase alpha
chr3_+_130894157 0.32 ENST00000504948.5
ENST00000513801.5
ENST00000505072.5
ATPase secretory pathway Ca2+ transporting 1
chr6_+_35297809 0.32 ENST00000316637.7
DEF6 guanine nucleotide exchange factor
chrX_+_30215551 0.32 ENST00000378988.5
MAGE family member B2
chrX_-_15664798 0.32 ENST00000380342.4
collectrin, amino acid transport regulator
chr18_-_21704763 0.31 ENST00000580981.5
ENST00000289119.7
abhydrolase domain containing 3, phospholipase
chr3_+_130893959 0.30 ENST00000508532.5
ENST00000533801.6
ATPase secretory pathway Ca2+ transporting 1
chr9_+_136952256 0.30 ENST00000371633.8
lipocalin 12
chr2_+_230712817 0.30 ENST00000258418.10
calcium binding protein 39
chr3_+_50267606 0.29 ENST00000618865.4
semaphorin 3B
chr17_-_48430205 0.29 ENST00000336915.11
ENST00000584924.5
src kinase associated phosphoprotein 1
chrX_-_153724044 0.28 ENST00000423827.5
ENST00000458587.8
B cell receptor associated protein 31
chr11_+_112175526 0.28 ENST00000532612.5
ENST00000438022.5
beta-carotene oxygenase 2
chr1_+_156147350 0.28 ENST00000435124.5
ENST00000633494.1
semaphorin 4A
chr11_+_69294107 0.28 ENST00000441339.3
ENST00000308946.3
ENST00000535407.1
myeloma overexpressed
chr9_-_83063135 0.28 ENST00000376447.4
RAS and EF-hand domain containing
chr2_-_96035974 0.27 ENST00000434632.5
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr3_+_130894382 0.27 ENST00000509662.5
ENST00000328560.12
ENST00000428331.6
ENST00000359644.7
ENST00000422190.6
ATPase secretory pathway Ca2+ transporting 1
chrX_-_153724343 0.27 ENST00000442093.5
ENST00000345046.12
ENST00000645377.1
ENST00000672675.1
ENST00000647529.1
ENST00000429550.5
B cell receptor associated protein 31
chr1_-_206003385 0.27 ENST00000617070.5
RAB7B, member RAS oncogene family
chr11_-_90223059 0.26 ENST00000457199.6
ENST00000530765.5
cysteine and histidine rich domain containing 1
chr9_+_136952896 0.26 ENST00000371632.7
lipocalin 12
chr5_-_176537361 0.26 ENST00000274811.9
ring finger protein 44
chr11_+_112175501 0.25 ENST00000357685.11
ENST00000361053.8
beta-carotene oxygenase 2
chr2_+_108786738 0.25 ENST00000412964.6
ENST00000295124.9
coiled-coil domain containing 138
chr1_+_212608628 0.25 ENST00000613954.4
ENST00000341491.9
ENST00000366985.5
activating transcription factor 3
chr5_+_151253171 0.25 ENST00000357164.4
GM2 ganglioside activator
chr20_+_10034963 0.25 ENST00000378392.6
ankyrin repeat and EF-hand domain containing 1
chr7_+_130381092 0.24 ENST00000484324.1
carboxypeptidase A1
chr14_+_96256194 0.24 ENST00000216629.11
ENST00000553356.1
bradykinin receptor B1
chr1_+_196774813 0.24 ENST00000471440.6
ENST00000391985.7
ENST00000617219.1
ENST00000367425.9
complement factor H related 3
chr2_+_112977998 0.24 ENST00000259205.5
ENST00000376489.6
interleukin 36 gamma
chr20_+_10035029 0.24 ENST00000378380.4
ankyrin repeat and EF-hand domain containing 1
chr3_+_130850585 0.24 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr5_+_141636941 0.24 ENST00000444782.5
ENST00000297164.8
ENST00000521367.5
RELT like 2
chr4_-_25863537 0.23 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr21_+_38272250 0.23 ENST00000398932.5
potassium inwardly rectifying channel subfamily J member 15
chr19_-_55160668 0.23 ENST00000588076.1
dynein axonemal assembly factor 3
chr18_+_58045642 0.23 ENST00000676223.1
ENST00000675147.1
NEDD4 like E3 ubiquitin protein ligase
chr5_+_141637398 0.23 ENST00000518856.1
RELT like 2
chr8_+_8701891 0.23 ENST00000519106.2
claudin 23
chr11_-_90223036 0.23 ENST00000320585.11
cysteine and histidine rich domain containing 1
chr6_+_31827730 0.22 ENST00000375650.5
heat shock protein family A (Hsp70) member 1B
chr21_+_38272291 0.22 ENST00000438657.5
potassium inwardly rectifying channel subfamily J member 15
chr8_-_55773295 0.22 ENST00000523423.5
ENST00000523073.5
ENST00000519784.5
ENST00000519780.5
ENST00000521229.5
ENST00000434581.7
ENST00000522576.5
ENST00000523180.5
ENST00000522090.5
transmembrane protein 68
chr20_+_57329801 0.22 ENST00000371263.8
ENST00000345868.8
ENST00000371260.8
ENST00000418127.5
SPO11 initiator of meiotic double stranded breaks
chr17_+_7355123 0.22 ENST00000389982.8
ENST00000576060.6
ENST00000330767.4
transmembrane protein 95
chr8_-_55773389 0.22 ENST00000334667.6
transmembrane protein 68
chr19_-_2051224 0.22 ENST00000309340.11
ENST00000589534.2
ENST00000250896.9
ENST00000589509.5
MAPK interacting serine/threonine kinase 2
chr3_+_32391841 0.22 ENST00000334983.10
CKLF like MARVEL transmembrane domain containing 7
chrX_+_147981324 0.22 ENST00000370467.8
FMR1 neighbor
chr21_+_41361999 0.22 ENST00000436410.5
ENST00000435611.6
ENST00000330714.8
MX dynamin like GTPase 2
chr1_-_10796636 0.22 ENST00000377022.8
ENST00000344008.5
castor zinc finger 1
chr19_-_54364983 0.21 ENST00000434277.6
leukocyte associated immunoglobulin like receptor 1
chr19_+_8053000 0.21 ENST00000390669.7
C-C motif chemokine ligand 25
chr19_-_54364863 0.21 ENST00000348231.8
leukocyte associated immunoglobulin like receptor 1
chr22_+_38057200 0.21 ENST00000404072.7
ENST00000424694.5
protein interacting with PRKCA 1
chr1_+_196888014 0.21 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
complement factor H related 4
chr16_+_85908988 0.21 ENST00000566369.1
interferon regulatory factor 8
chr20_+_18813777 0.21 ENST00000377428.4
SCP2 sterol binding domain containing 1
chr3_-_195876635 0.21 ENST00000672669.1
ENST00000672886.1
ENST00000672098.1
ENST00000671767.1
ENST00000672548.1
tyrosine kinase non receptor 2
chr4_+_41935423 0.21 ENST00000504986.6
transmembrane protein 33
chr14_+_39265278 0.21 ENST00000554392.5
ENST00000555716.5
ENST00000341749.7
ENST00000557038.5
MIA SH3 domain ER export factor 2
chr1_-_247758680 0.20 ENST00000408896.4
olfactory receptor family 1 subfamily C member 1
chr6_-_105179952 0.20 ENST00000254765.4
popeye domain containing 3
chr17_+_42562120 0.20 ENST00000585811.1
ENST00000585909.1
ENST00000586771.1
ENST00000421097.6
ENST00000591779.5
ENST00000393818.3
ENST00000587858.5
ENST00000587214.1
ENST00000587157.1
ENST00000590958.5
Coenzyme A synthase
chr1_+_110034607 0.20 ENST00000369795.8
striatin interacting protein 1
chr1_+_247416166 0.19 ENST00000391827.3
ENST00000336119.8
NLR family pyrin domain containing 3
chr17_-_17582417 0.19 ENST00000395783.5
phosphatidylethanolamine N-methyltransferase
chr14_-_92748570 0.19 ENST00000553918.1
ENST00000555699.5
ENST00000334869.9
ENST00000553802.5
ENST00000554397.5
ENST00000554919.5
ENST00000554080.5
ENST00000553371.1
ENST00000557434.5
ENST00000393218.6
legumain
chr9_+_105694519 0.19 ENST00000374692.8
ENST00000434214.1
transmembrane protein 38B
chr14_-_77320855 0.19 ENST00000556394.2
ENST00000261534.9
protein O-mannosyltransferase 2
chr22_+_38057371 0.19 ENST00000437453.5
ENST00000356976.8
protein interacting with PRKCA 1
chr3_-_59049947 0.19 ENST00000491845.5
ENST00000472469.5
ENST00000482387.6
ENST00000295966.11
CFAP20 domain containing
chr10_+_37125593 0.19 ENST00000374660.7
ENST00000602533.7
ENST00000361713.2
ankyrin repeat domain 30A
chr6_-_10694533 0.18 ENST00000460742.6
ENST00000379586.5
ENST00000259983.8
chromosome 6 open reading frame 52
chr17_-_45410414 0.18 ENST00000532038.5
ENST00000528677.1
Rho GTPase activating protein 27
chr1_+_19643708 0.18 ENST00000439664.5
ENST00000621723.4
NBL1, DAN family BMP antagonist
chr19_-_10517439 0.18 ENST00000333430.6
sphingosine-1-phosphate receptor 5
chr1_+_110873135 0.18 ENST00000271324.6
CD53 molecule
chr12_+_10010627 0.18 ENST00000338896.11
ENST00000396502.5
C-type lectin domain family 12 member B
chr11_-_47848467 0.18 ENST00000378460.6
nucleoporin 160
chr19_+_8052752 0.17 ENST00000315626.6
ENST00000253451.9
C-C motif chemokine ligand 25
chr19_+_45251363 0.17 ENST00000620044.4
microtubule affinity regulating kinase 4
chr3_-_36739791 0.17 ENST00000416516.2
doublecortin like kinase 3
chr19_-_14518383 0.17 ENST00000254322.3
ENST00000595139.2
DnaJ heat shock protein family (Hsp40) member B1
chr3_+_48223479 0.17 ENST00000652295.2
cathelicidin antimicrobial peptide
chr4_+_41935114 0.17 ENST00000508448.5
ENST00000513702.5
ENST00000325094.9
transmembrane protein 33
chr11_+_34624244 0.17 ENST00000529527.5
ENST00000531728.5
ENST00000525253.5
ETS homologous factor
chr1_+_212565334 0.17 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chr12_+_66302486 0.17 ENST00000247815.9
DNA helicase B
chrX_-_155334580 0.17 ENST00000369449.7
ENST00000321926.4
chloride intracellular channel 2
chr6_+_72621621 0.17 ENST00000342056.6
ENST00000628967.2
ENST00000355194.8
ENST00000355635.7
ENST00000402622.6
ENST00000403813.6
ENST00000414165.6
potassium voltage-gated channel subfamily Q member 5
chr14_-_102087034 0.17 ENST00000216281.13
ENST00000553585.5
heat shock protein 90 alpha family class A member 1
chr22_-_40862070 0.17 ENST00000307221.5
DnaJ heat shock protein family (Hsp40) member B7
chr16_+_29778252 0.17 ENST00000400752.6
zymogen granule protein 16
chr12_+_34022462 0.17 ENST00000538927.1
ENST00000266483.7
ALG10 alpha-1,2-glucosyltransferase
chr1_-_11262530 0.17 ENST00000361445.9
mechanistic target of rapamycin kinase
chr2_+_202634960 0.16 ENST00000392238.3
family with sequence similarity 117 member B
chr12_+_51238854 0.16 ENST00000549732.6
ENST00000604900.5
DAZ associated protein 2
chr14_-_77320741 0.16 ENST00000682795.1
ENST00000682247.1
protein O-mannosyltransferase 2
chr10_-_72354895 0.16 ENST00000444643.8
ENST00000338820.7
ENST00000394903.6
DnaJ heat shock protein family (Hsp40) member B12
chr2_+_172556007 0.16 ENST00000392571.6
pyruvate dehydrogenase kinase 1
chr11_-_105023136 0.16 ENST00000526056.5
ENST00000531367.5
ENST00000456094.1
ENST00000444749.6
ENST00000393141.6
ENST00000418434.5
ENST00000260315.8
caspase 5
chrX_-_119606412 0.16 ENST00000304449.8
NFKB repressing factor
chr6_+_4889992 0.16 ENST00000343762.5
chromodomain Y like
chr10_-_5499544 0.16 ENST00000380332.5
calmodulin like 5
chr9_-_34372832 0.16 ENST00000379142.3
myogenesis regulating glycosidase (putative)
chr7_-_43906577 0.16 ENST00000603700.1
ENST00000439702.5
ENST00000453200.6
ENST00000402306.7
ENST00000443736.5
ENST00000446958.1
URGCP-MRPS24 readthrough
upregulator of cell proliferation
chr14_-_77320813 0.16 ENST00000682467.1
protein O-mannosyltransferase 2
chr6_-_31815244 0.16 ENST00000375654.5
heat shock protein family A (Hsp70) member 1 like
chr19_-_344786 0.16 ENST00000264819.7
MIER family member 2
chr11_-_47848313 0.16 ENST00000530326.5
ENST00000528071.5
nucleoporin 160
chr22_-_38302990 0.16 ENST00000612795.2
ENST00000451964.5
casein kinase 1 epsilon
chr1_-_206202827 0.16 ENST00000431655.2
ENST00000367128.8
family with sequence similarity 72 member A
chr1_-_121184292 0.15 ENST00000452190.2
ENST00000619376.4
ENST00000369390.7
family with sequence similarity 72 member B
chr1_+_161524539 0.15 ENST00000309758.6
heat shock protein family A (Hsp70) member 6
chr10_+_116324440 0.15 ENST00000333254.4
coiled-coil domain containing 172
chr22_-_26565362 0.15 ENST00000398110.6
tyrosylprotein sulfotransferase 2
chr16_+_2236443 0.15 ENST00000320700.10
ENST00000613572.4
ENST00000567494.5
deoxyribonuclease 1 like 2
chr15_+_34102037 0.15 ENST00000397766.4
piggyBac transposable element derived 4
chr14_-_24576240 0.15 ENST00000216336.3
cathepsin G
chr6_+_31815532 0.15 ENST00000375651.7
ENST00000608703.1
heat shock protein family A (Hsp70) member 1A
chr16_+_28974813 0.15 ENST00000352260.11
sphingolipid transporter 1 (putative)
chr1_+_67307837 0.15 ENST00000541374.6
ENST00000371000.5
ENST00000674203.2
interleukin 12 receptor subunit beta 2
chr11_+_125903320 0.15 ENST00000525943.1
DEAD-box helicase 25
chrX_-_73214793 0.15 ENST00000373517.4
nucleosome assembly protein 1 like 2
chr3_+_4680617 0.15 ENST00000648212.1
inositol 1,4,5-trisphosphate receptor type 1
chr7_+_128937917 0.14 ENST00000357234.10
ENST00000613821.4
ENST00000477535.5
ENST00000479582.5
ENST00000464557.5
ENST00000402030.6
interferon regulatory factor 5
chr17_-_61928005 0.14 ENST00000444766.7
integrator complex subunit 2
chr19_-_1132208 0.14 ENST00000438103.6
strawberry notch homolog 2
chr5_-_74767105 0.14 ENST00000509430.5
ENST00000296805.8
ENST00000345239.6
ENST00000427854.6
ENST00000506778.1
GTP dependent ribosome recycling factor mitochondrial 2
chr6_-_85593805 0.14 ENST00000513865.5
ENST00000369627.6
ENST00000314673.8
ENST00000683541.1
ENST00000682939.1
ENST00000684570.1
ENST00000682491.1
ENST00000683898.1
ENST00000684647.1
ENST00000683643.1
ENST00000684281.1
ENST00000682991.1
ENST00000683754.1
ENST00000682682.1
ENST00000681981.1
ENST00000682738.1
ENST00000509338.6
ENST00000684717.1
ENST00000682660.1
ENST00000515216.6
ENST00000683479.1
ENST00000508658.6
ENST00000682497.1
ENST00000684118.1
ENST00000346348.7
sorting nexin 14
chr2_-_96740034 0.14 ENST00000264963.9
ENST00000377079.8
lectin, mannose binding 2 like
chr2_+_172556039 0.14 ENST00000410055.5
ENST00000282077.8
pyruvate dehydrogenase kinase 1
chr11_+_46332905 0.14 ENST00000343674.10
diacylglycerol kinase zeta
chr21_-_41926680 0.14 ENST00000329623.11
C2 calcium dependent domain containing 2
chr19_-_474880 0.14 ENST00000382696.7
ENST00000315489.5
outer dense fiber of sperm tails 3 like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0002445 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.4 2.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.3 1.4 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.3 1.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.3 0.8 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 1.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 0.7 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.2 0.7 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.2 0.5 GO:0016108 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.2 0.5 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2 1.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.5 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 1.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.8 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.4 GO:0098905 pulmonary valve formation(GO:0003193) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.1 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.5 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 1.6 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.4 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.4 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.9 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.1 0.6 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.3 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.5 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 2.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.1 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1 0.2 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.9 GO:0032119 sequestering of zinc ion(GO:0032119)
0.1 0.2 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.1 0.2 GO:1990918 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.8 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.2 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:1901389 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.0 0.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.4 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:1903973 regulation of interleukin-4-mediated signaling pathway(GO:1902214) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) regulation of positive thymic T cell selection(GO:1902232) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0 0.3 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.1 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.3 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.5 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.4 GO:0002934 desmosome organization(GO:0002934) enamel mineralization(GO:0070166)
0.0 0.1 GO:2000724 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.4 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.3 GO:0046477 glycoside catabolic process(GO:0016139) glycosylceramide catabolic process(GO:0046477)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.8 GO:0007620 copulation(GO:0007620)
0.0 0.1 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.2 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.1 GO:1903487 positive regulation of vascular wound healing(GO:0035470) regulation of lactation(GO:1903487)
0.0 0.1 GO:0070662 erythropoietin-mediated signaling pathway(GO:0038162) mast cell proliferation(GO:0070662)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 2.5 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:1901535 chromatin reprogramming in the zygote(GO:0044725) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.0 0.1 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0070943 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.1 GO:0060621 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.0 GO:0070105 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.0 GO:0046086 adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175) adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.2 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.1 GO:0070054 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 1.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0042359 vitamin D metabolic process(GO:0042359)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.3 0.8 GO:0019031 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.2 1.1 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.5 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.2 GO:0030849 autosome(GO:0030849)
0.1 0.4 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.3 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 1.5 GO:0005922 connexon complex(GO:0005922)
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.3 GO:0072557 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:1990913 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.0 2.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 1.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.0 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 1.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.1 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 1.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 0.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.9 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.3 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 0.4 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.4 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.8 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.1 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.3 GO:0016936 galactoside binding(GO:0016936)
0.1 1.1 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.2 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 0.2 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.4 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.4 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 0.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 0.2 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0002135 CTP binding(GO:0002135)
0.0 0.1 GO:0047750 C-8 sterol isomerase activity(GO:0000247) cholestenol delta-isomerase activity(GO:0047750)
0.0 1.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 2.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.2 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 1.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004914 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.0 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 8.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.0 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 1.9 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 0.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.6 GO:0043531 ADP binding(GO:0043531)
0.0 0.0 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.8 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.7 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 1.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC