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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for HSF4

Z-value: 0.29

Motif logo

Transcription factors associated with HSF4

Gene Symbol Gene ID Gene Info
ENSG00000102878.18 heat shock transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF4hg38_v1_chr16_+_67164780_67164812-0.206.3e-01Click!

Activity profile of HSF4 motif

Sorted Z-values of HSF4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_45026296 0.50 ENST00000296130.5
C-type lectin domain family 3 member B
chr14_-_59630806 0.41 ENST00000342503.8
reticulon 1
chr14_-_59630582 0.40 ENST00000395090.5
reticulon 1
chr8_-_119592954 0.34 ENST00000522167.5
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr10_-_20897288 0.25 ENST00000377122.9
nebulette
chr11_-_111923722 0.25 ENST00000527950.5
crystallin alpha B
chr11_-_111911759 0.23 ENST00000650687.2
crystallin alpha B
chr2_+_209579399 0.23 ENST00000360351.8
microtubule associated protein 2
chr11_-_111910790 0.23 ENST00000533280.6
crystallin alpha B
chr2_+_209579598 0.23 ENST00000445941.5
ENST00000673860.1
microtubule associated protein 2
chr11_-_111910888 0.22 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr11_-_111910830 0.22 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr10_+_129467178 0.20 ENST00000306010.8
ENST00000651593.1
O-6-methylguanine-DNA methyltransferase
chr7_-_56051288 0.18 ENST00000419984.6
ENST00000413218.5
ENST00000275605.8
ENST00000424596.1
ENST00000421312.5
ENST00000416592.1
phosphoserine phosphatase
chr7_-_56051544 0.18 ENST00000395471.7
phosphoserine phosphatase
chrX_+_109536641 0.18 ENST00000372107.5
nuclear transport factor 2 like export factor 2
chr4_+_76011171 0.18 ENST00000513353.5
ENST00000341029.9
ADP-ribosyltransferase 3 (inactive)
chr11_+_107928394 0.17 ENST00000320578.3
RAB39A, member RAS oncogene family
chr9_+_121207774 0.16 ENST00000373823.7
gelsolin
chr21_-_30372265 0.16 ENST00000399889.4
keratin associated protein 13-2
chr17_+_35147807 0.16 ENST00000394570.7
ENST00000268876.9
unc-45 myosin chaperone B
chr9_-_135699473 0.16 ENST00000425225.2
ENST00000298466.9
spermatogenesis and oogenesis specific basic helix-loop-helix 1
chr8_+_142834801 0.15 ENST00000220940.2
glycosylphosphatidylinositol anchored molecule like
chr11_+_86302211 0.15 ENST00000533986.5
ENST00000278483.8
heat shock protein nuclear import factor hikeshi
chr2_+_209579429 0.14 ENST00000361559.8
microtubule associated protein 2
chr19_-_18538371 0.13 ENST00000596015.1
FKBP prolyl isomerase 8
chr9_-_135499846 0.13 ENST00000429260.7
chromosome 9 open reading frame 116
chr16_-_8861744 0.12 ENST00000569398.5
ENST00000568968.1
calcium regulated heat stable protein 1
chrX_+_54920796 0.12 ENST00000442098.5
ENST00000430420.5
ENST00000453081.5
ENST00000319167.12
ENST00000622017.4
ENST00000375022.8
ENST00000399736.5
ENST00000440072.5
ENST00000173898.12
ENST00000431115.5
ENST00000440759.5
ENST00000375041.6
trophinin
chr16_-_8861713 0.12 ENST00000567554.5
calcium regulated heat stable protein 1
chr8_-_27614681 0.11 ENST00000519472.5
ENST00000523589.5
ENST00000522413.5
ENST00000523396.1
ENST00000316403.15
clusterin
chr2_+_200305976 0.11 ENST00000358677.9
spermatogenesis associated serine rich 2 like
chr11_+_66002754 0.11 ENST00000527348.1
BAF nuclear assembly factor 1
chrX_+_109536832 0.11 ENST00000372106.6
nuclear transport factor 2 like export factor 2
chr11_-_83285965 0.11 ENST00000529073.5
ENST00000529611.5
coiled-coil domain containing 90B
chr1_+_65309517 0.11 ENST00000371069.5
DnaJ heat shock protein family (Hsp40) member C6
chr11_+_66002475 0.11 ENST00000312175.7
ENST00000533166.5
BAF nuclear assembly factor 1
chr2_+_200306648 0.11 ENST00000409140.8
spermatogenesis associated serine rich 2 like
chr16_-_8861799 0.11 ENST00000610831.4
ENST00000614449.4
calcium regulated heat stable protein 1
chr5_-_134371004 0.10 ENST00000521755.1
ENST00000523054.5
ENST00000518409.1
cyclin dependent kinase like 3
novel transcript
chr6_-_76072654 0.10 ENST00000369950.8
ENST00000611179.4
ENST00000369963.5
interphotoreceptor matrix proteoglycan 1
chr14_+_104745960 0.10 ENST00000556623.1
ENST00000555674.1
adenylosuccinate synthase 1
chr11_+_66002225 0.10 ENST00000445560.6
ENST00000530204.1
BAF nuclear assembly factor 1
chr11_-_86672419 0.09 ENST00000524826.7
ENST00000532471.1
malic enzyme 3
chr3_+_138347648 0.09 ENST00000614350.4
ENST00000289104.8
muscle RAS oncogene homolog
chr19_+_49851205 0.09 ENST00000601675.5
PTOV1 extended AT-hook containing adaptor protein
chr6_-_41201128 0.09 ENST00000483722.2
triggering receptor expressed on myeloid cells like 2
chr21_+_30396030 0.09 ENST00000355459.4
keratin associated protein 13-1
chr11_-_83286328 0.09 ENST00000525503.5
coiled-coil domain containing 90B
chr4_-_17512079 0.09 ENST00000428702.6
ENST00000508623.5
ENST00000513615.5
ENST00000281243.10
quinoid dihydropteridine reductase
chr11_-_83286377 0.09 ENST00000455220.6
ENST00000529689.5
coiled-coil domain containing 90B
chr15_-_89211803 0.09 ENST00000563254.1
retinaldehyde binding protein 1
chr19_+_49851173 0.08 ENST00000599732.5
PTOV1 extended AT-hook containing adaptor protein
chr5_+_134371561 0.08 ENST00000265339.7
ENST00000506787.5
ENST00000507277.1
ubiquitin conjugating enzyme E2 B
chr19_+_49851136 0.08 ENST00000391842.5
PTOV1 extended AT-hook containing adaptor protein
chr18_+_11751467 0.08 ENST00000535121.5
G protein subunit alpha L
chr5_-_178187364 0.08 ENST00000463439.3
germ cell-less 2, spermatogenesis associated
chr2_-_69437588 0.08 ENST00000394305.5
NFU1 iron-sulfur cluster scaffold
chr11_-_10568571 0.08 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr5_+_173144442 0.08 ENST00000231668.13
ENST00000351486.10
ENST00000352523.10
ENST00000393770.4
BCL2 interacting protein 1
chr1_-_120176450 0.08 ENST00000578049.4
SEC22 homolog B, vesicle trafficking protein
chr11_-_27700472 0.08 ENST00000418212.5
ENST00000533246.5
brain derived neurotrophic factor
chr12_-_110502065 0.07 ENST00000447578.6
ENST00000546588.1
ENST00000360579.11
ENST00000549578.6
ENST00000549970.5
VPS29 retromer complex component
chr9_-_33025052 0.07 ENST00000673248.1
aprataxin
chr11_+_20363780 0.07 ENST00000532505.1
HIV-1 Tat interactive protein 2
chr7_+_76303547 0.07 ENST00000429938.1
heat shock protein family B (small) member 1
chr11_+_20363685 0.07 ENST00000530266.5
ENST00000451739.7
ENST00000421577.6
ENST00000443524.6
ENST00000419348.6
HIV-1 Tat interactive protein 2
chr21_+_42974510 0.07 ENST00000432907.6
ENST00000291547.10
PBX/knotted 1 homeobox 1
chr22_+_32475257 0.07 ENST00000397426.5
F-box protein 7
chr9_+_34989641 0.07 ENST00000453597.8
ENST00000312316.9
ENST00000458263.6
ENST00000537321.5
ENST00000682809.1
ENST00000684748.1
DnaJ heat shock protein family (Hsp40) member B5
chr3_-_185938006 0.07 ENST00000342294.4
ENST00000453386.7
ENST00000382191.4
transformer 2 beta homolog
chr3_+_159069252 0.07 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1 readthrough
chr4_-_151226427 0.07 ENST00000304527.8
ENST00000409598.8
SH3 domain containing 19
chr6_+_36197356 0.07 ENST00000446974.1
ENST00000454960.1
bromodomain and PHD finger containing 3
chr15_-_58065870 0.07 ENST00000537372.5
aldehyde dehydrogenase 1 family member A2
chr12_-_76423256 0.06 ENST00000546946.5
oxysterol binding protein like 8
chr5_+_141223332 0.06 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
protocadherin beta 14
novel protein
chr15_-_58065734 0.06 ENST00000347587.7
aldehyde dehydrogenase 1 family member A2
chr7_+_76302665 0.06 ENST00000248553.7
ENST00000674638.1
ENST00000674547.1
ENST00000675226.1
ENST00000675538.1
ENST00000676231.1
ENST00000675134.1
ENST00000675906.1
ENST00000674650.1
heat shock protein family B (small) member 1
chr5_+_119354771 0.06 ENST00000503646.1
TNF alpha induced protein 8
chr8_+_61287950 0.06 ENST00000519846.5
ENST00000325897.5
ENST00000523868.2
ENST00000518592.5
clavesin 1
chr15_-_58065703 0.06 ENST00000249750.9
aldehyde dehydrogenase 1 family member A2
chr17_-_78577383 0.06 ENST00000389840.7
dynein axonemal heavy chain 17
chr6_-_106325416 0.06 ENST00000343245.7
autophagy related 5
chr17_-_76726753 0.06 ENST00000617192.4
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
chr1_-_45521854 0.06 ENST00000372079.1
ENST00000319248.13
peroxiredoxin 1
chr1_-_45521931 0.06 ENST00000447184.6
ENST00000262746.5
peroxiredoxin 1
chr3_+_186783567 0.05 ENST00000323963.10
ENST00000440191.6
eukaryotic translation initiation factor 4A2
chrX_-_107000185 0.05 ENST00000355610.9
MORC family CW-type zinc finger 4
chr17_-_42016680 0.05 ENST00000674497.1
DnaJ heat shock protein family (Hsp40) member C7
chr9_+_69123009 0.05 ENST00000647986.1
tight junction protein 2
chr2_+_197500398 0.05 ENST00000604458.1
HSPE1-MOB4 readthrough
chr7_+_157336988 0.05 ENST00000262177.9
ENST00000417758.5
ENST00000443280.5
DnaJ heat shock protein family (Hsp40) member B6
chr15_+_43800586 0.05 ENST00000442995.4
ENST00000458412.2
huntingtin interacting protein K
chr6_+_54307856 0.05 ENST00000370869.7
tubulointerstitial nephritis antigen
chr1_-_228425350 0.05 ENST00000366696.2
H3.4 histone
chrX_-_103688033 0.05 ENST00000434230.5
ENST00000418819.5
ENST00000360458.5
mortality factor 4 like 2
chr19_+_6135635 0.05 ENST00000588304.5
ENST00000588722.5
ENST00000588485.6
ENST00000591403.5
ENST00000586696.5
ENST00000681525.1
ENST00000589401.5
acyl-CoA synthetase bubblegum family member 2
chr18_+_13465009 0.05 ENST00000593236.1
ENST00000678400.1
low density lipoprotein receptor class A domain containing 4
chr6_-_41941795 0.05 ENST00000372991.9
cyclin D3
chr9_-_33025088 0.05 ENST00000436040.7
aprataxin
chr4_-_94342826 0.04 ENST00000295256.10
hematopoietic prostaglandin D synthase
chr1_-_26306576 0.04 ENST00000421827.2
ENST00000374215.5
ENST00000374223.5
ENST00000357089.8
ENST00000314675.11
ENST00000423664.5
ENST00000374221.7
UBX domain protein 11
chr17_+_34319427 0.04 ENST00000394620.2
C-C motif chemokine ligand 8
chrX_-_153673778 0.04 ENST00000340888.8
pregnancy up-regulated nonubiquitous CaM kinase
chr3_+_96814552 0.04 ENST00000470610.6
ENST00000389672.9
EPH receptor A6
chr20_-_36951837 0.04 ENST00000262878.5
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr11_+_20364119 0.04 ENST00000532081.1
ENST00000531058.1
HIV-1 Tat interactive protein 2
chr1_+_21468442 0.04 ENST00000619554.1
NBPF member 3
chr20_-_36951637 0.04 ENST00000646066.1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chrX_+_151176582 0.04 ENST00000218316.4
G protein-coupled receptor 50
chr1_+_40450472 0.04 ENST00000361584.5
ZFP69 zinc finger protein B
chr3_+_133400046 0.04 ENST00000302334.3
beaded filament structural protein 2
chr3_+_46497970 0.04 ENST00000296142.4
receptor transporter protein 3
chr6_-_41941728 0.04 ENST00000414200.6
cyclin D3
chrX_-_103688090 0.04 ENST00000433176.6
mortality factor 4 like 2
chr15_+_78872809 0.04 ENST00000331268.9
mortality factor 4 like 1
chr12_-_9733083 0.04 ENST00000542530.5
C-type lectin like 1
chr18_+_13611764 0.04 ENST00000585931.5
low density lipoprotein receptor class A domain containing 4
chr13_-_41019289 0.04 ENST00000239882.7
E74 like ETS transcription factor 1
chr1_-_25905989 0.04 ENST00000399728.5
stathmin 1
chr16_-_9943182 0.04 ENST00000535259.6
glutamate ionotropic receptor NMDA type subunit 2A
chr12_+_6535278 0.04 ENST00000396858.5
glyceraldehyde-3-phosphate dehydrogenase
chr6_+_154995258 0.04 ENST00000682666.1
TIAM Rac1 associated GEF 2
chr11_-_10568650 0.04 ENST00000256178.8
lymphatic vessel endothelial hyaluronan receptor 1
chr12_-_9733292 0.03 ENST00000621400.4
ENST00000327839.3
C-type lectin like 1
chr1_-_6200831 0.03 ENST00000497965.5
ribosomal protein L22
chr20_-_36951701 0.03 ENST00000646673.2
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr15_+_78872881 0.03 ENST00000559930.5
ENST00000426013.7
mortality factor 4 like 1
chr4_-_83485065 0.03 ENST00000515303.2
ENST00000321945.12
ENST00000503217.2
abraxas 1, BRCA1 A complex subunit
chr17_+_42017020 0.03 ENST00000307641.9
NFKB inhibitor interacting Ras like 2
chr20_-_36951665 0.03 ENST00000643918.1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr2_+_85539158 0.03 ENST00000306434.8
methionine adenosyltransferase 2A
chr17_+_2033393 0.03 ENST00000570477.6
diphthamide biosynthesis 1
chr20_-_44960348 0.03 ENST00000372813.4
translocase of outer mitochondrial membrane 34
chr6_-_41941507 0.03 ENST00000372987.8
cyclin D3
chr21_-_39349048 0.03 ENST00000380748.5
ENST00000380749.10
high mobility group nucleosome binding domain 1
chrX_-_107982370 0.03 ENST00000302917.1
testis expressed 13B
chr6_+_35737028 0.03 ENST00000373869.7
ENST00000373866.4
armadillo repeat containing 12
chr20_-_63463843 0.03 ENST00000637193.1
potassium voltage-gated channel subfamily Q member 2
chr12_+_103587266 0.03 ENST00000388887.7
stabilin 2
chr12_+_110502200 0.03 ENST00000409246.5
ENST00000392672.8
ENST00000409425.5
RAD9 checkpoint clamp component B
chr17_+_76726827 0.03 ENST00000589977.5
ENST00000615984.4
ENST00000591571.5
ENST00000341249.11
ENST00000592849.5
ENST00000586738.5
ENST00000588783.5
ENST00000588563.5
ENST00000586752.5
ENST00000588302.5
ENST00000590964.5
ENST00000588822.1
methyltransferase like 23
chr7_-_151410677 0.03 ENST00000621812.2
ENST00000477459.5
WD repeat domain 86
chr2_+_197500371 0.03 ENST00000409468.1
ENST00000233893.10
heat shock protein family E (Hsp10) member 1
chr15_+_96325935 0.03 ENST00000421109.6
nuclear receptor subfamily 2 group F member 2
chr6_+_35737078 0.03 ENST00000288065.6
armadillo repeat containing 12
chr17_+_76726948 0.03 ENST00000586200.1
methyltransferase like 23
chr2_+_200306340 0.03 ENST00000451764.6
spermatogenesis associated serine rich 2 like
chr18_-_46917432 0.03 ENST00000324794.11
ENST00000545673.5
ENST00000585916.6
protein inhibitor of activated STAT 2
chr12_+_110502307 0.03 ENST00000409778.7
ENST00000409300.6
RAD9 checkpoint clamp component B
chr17_+_47323941 0.03 ENST00000331493.7
ENST00000519772.5
ENST00000517484.5
EF-hand calcium binding domain 13
chr18_+_46917561 0.03 ENST00000683218.1
katanin catalytic subunit A1 like 2
chr10_+_24239181 0.02 ENST00000438429.5
KIAA1217
chr7_+_157336961 0.02 ENST00000429029.6
DnaJ heat shock protein family (Hsp40) member B6
chr19_+_2269520 0.02 ENST00000602676.6
ENST00000582888.8
ornithine decarboxylase antizyme 1
chr11_+_124622853 0.02 ENST00000441174.8
ENST00000531667.5
transforming growth factor beta regulator 1
chr9_-_13279407 0.02 ENST00000546205.5
multiple PDZ domain crumbs cell polarity complex component
chr11_+_75562274 0.02 ENST00000532356.5
ENST00000524558.5
serpin family H member 1
chr1_+_28259473 0.02 ENST00000253063.4
sestrin 2
chr11_+_75562242 0.02 ENST00000526397.5
ENST00000529643.1
ENST00000525492.5
ENST00000530284.5
ENST00000358171.8
serpin family H member 1
chr19_-_42217667 0.02 ENST00000336034.8
ENST00000596251.6
ENST00000598200.1
ENST00000598727.5
death effector domain containing 2
chr9_-_95317671 0.02 ENST00000490972.7
ENST00000647778.1
ENST00000649611.1
ENST00000289081.8
FA complementation group C
chr2_+_200306048 0.02 ENST00000409988.7
ENST00000409385.5
spermatogenesis associated serine rich 2 like
chr12_-_110445540 0.02 ENST00000547365.1
actin related protein 2/3 complex subunit 3
chr12_-_122526929 0.02 ENST00000331738.12
ENST00000528279.1
ENST00000344591.8
ENST00000526560.6
arginine and serine rich coiled-coil 2
chr22_-_40856565 0.02 ENST00000620312.4
ENST00000216218.8
ST13 Hsp70 interacting protein
chr21_+_33403466 0.02 ENST00000405436.5
interferon gamma receptor 2
chr6_+_31715339 0.02 ENST00000375824.1
ENST00000375825.7
lymphocyte antigen 6 family member G6D
chr2_+_200306519 0.02 ENST00000360760.9
spermatogenesis associated serine rich 2 like
chr11_+_75562056 0.02 ENST00000533603.5
serpin family H member 1
chr11_+_64186219 0.02 ENST00000543847.1
stress induced phosphoprotein 1
chr7_-_1160144 0.02 ENST00000397083.6
ENST00000401903.5
ENST00000316495.8
zinc finger AN1-type containing 2A
chr2_-_68252482 0.02 ENST00000234310.8
protein phosphatase 3 regulatory subunit B, alpha
chr19_+_52274443 0.02 ENST00000600821.5
ENST00000595149.5
ENST00000595000.5
ENST00000593612.1
zinc finger protein 766
chr17_-_8383164 0.02 ENST00000584164.6
ENST00000582556.5
ENST00000648839.1
ENST00000578812.5
ENST00000583011.6
ribosomal protein L26
chr15_-_85794902 0.02 ENST00000337975.6
kelch like family member 25
chrX_-_140784366 0.02 ENST00000674533.1
cerebellar degeneration related protein 1
chr20_-_23750929 0.02 ENST00000304749.7
cystatin SN
chr10_-_73096850 0.02 ENST00000307116.6
ENST00000373008.6
ENST00000394890.7
prolyl 4-hydroxylase subunit alpha 1
chr5_+_446139 0.01 ENST00000315013.9
exocyst complex component 3
chr8_-_51809414 0.01 ENST00000356297.5
peroxidasin like
chr1_-_53238485 0.01 ENST00000371466.4
ENST00000371470.8
mago homolog, exon junction complex subunit
chr9_-_4666495 0.01 ENST00000475086.5
spermatogenesis associated 6 like
chr22_+_40857076 0.01 ENST00000614001.1
ENST00000357137.9
X-prolyl aminopeptidase 3
chr4_+_41359599 0.01 ENST00000513024.5
LIM and calponin homology domains 1
chrX_-_101293057 0.01 ENST00000372907.7
TATA-box binding protein associated factor 7 like
chr14_-_23071538 0.01 ENST00000555566.1
ENST00000338631.10
ENST00000557515.5
ENST00000397341.7
apoptotic chromatin condensation inducer 1
chr11_+_111245725 0.01 ENST00000280325.7
chromosome 11 open reading frame 53
chr11_+_193078 0.01 ENST00000342878.3
secretoglobin family 1C member 1
chr9_-_134917872 0.01 ENST00000616356.4
ENST00000371806.4
ficolin 1
chr19_-_46714269 0.01 ENST00000600194.5
protein kinase D2
chr18_+_59899988 0.01 ENST00000316660.7
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr1_+_154993581 0.01 ENST00000392487.1
lens epithelial protein
chr20_-_23751256 0.01 ENST00000398402.1
cystatin SN
chr2_+_227813834 0.01 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr7_+_142670734 0.01 ENST00000390398.3
T cell receptor beta variable 25-1
chr1_+_44213440 0.01 ENST00000361745.10
ENST00000446292.5
ENST00000440641.5
ENST00000372289.7
ENST00000436069.5
ENST00000437511.5
DNA methyltransferase 1 associated protein 1
chr1_-_173669835 0.01 ENST00000333279.3
ankyrin repeat domain 45
chr7_+_143959927 0.01 ENST00000624504.1
olfactory receptor family 2 subfamily F member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.2 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0060903 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.0 0.1 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0046061 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.0 GO:0070078 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079)
0.0 0.1 GO:0010044 response to aluminum ion(GO:0010044)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.0 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.5 GO:0001652 granular component(GO:0001652)
0.1 1.1 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:1990038 glial cytoplasmic inclusion(GO:0097409) classical Lewy body(GO:0097414) Lewy neurite(GO:0097462) Lewy body corona(GO:1990038)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.0 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0032567 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) guanyl deoxyribonucleotide binding(GO:0032560) dGTP binding(GO:0032567)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172) DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.1 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.0 GO:0033749 histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.0 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)