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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for IRF3

Z-value: 0.15

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Transcription factors associated with IRF3

Gene Symbol Gene ID Gene Info
ENSG00000126456.16 interferon regulatory factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF3hg38_v1_chr19_-_49665807_49665875-0.413.1e-01Click!

Activity profile of IRF3 motif

Sorted Z-values of IRF3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_162318475 0.29 ENST00000648433.1
interferon induced with helicase C domain 1
chr11_+_63536801 0.27 ENST00000255688.8
ENST00000439013.6
phospholipase A and acyltransferase 4
chr1_+_1013485 0.26 ENST00000649529.1
ISG15 ubiquitin like modifier
chr6_+_72212887 0.25 ENST00000523963.5
regulating synaptic membrane exocytosis 1
chr6_+_72212802 0.24 ENST00000401910.7
regulating synaptic membrane exocytosis 1
chr7_-_122886706 0.24 ENST00000313070.11
ENST00000334010.11
ENST00000615869.4
calcium dependent secretion activator 2
chr10_+_89332484 0.23 ENST00000371811.4
ENST00000680037.1
ENST00000679583.1
ENST00000679897.1
interferon induced protein with tetratricopeptide repeats 3
chr1_+_78649818 0.22 ENST00000370747.9
ENST00000438486.1
interferon induced protein 44
chr19_-_17405554 0.21 ENST00000252593.7
bone marrow stromal cell antigen 2
chr3_-_122564577 0.21 ENST00000477522.6
ENST00000360356.6
poly(ADP-ribose) polymerase family member 9
chr10_+_89327989 0.21 ENST00000679923.1
ENST00000680085.1
ENST00000371818.9
ENST00000680779.1
interferon induced protein with tetratricopeptide repeats 3
chr3_-_122564232 0.20 ENST00000471785.5
ENST00000466126.1
poly(ADP-ribose) polymerase family member 9
chr10_+_89327977 0.20 ENST00000681277.1
interferon induced protein with tetratricopeptide repeats 3
chr17_+_6755834 0.19 ENST00000346752.8
XIAP associated factor 1
chr6_+_32854179 0.19 ENST00000374859.3
proteasome 20S subunit beta 9
chr6_+_26440472 0.19 ENST00000494393.5
ENST00000482451.5
ENST00000471353.5
ENST00000361232.7
ENST00000487627.5
ENST00000496719.1
ENST00000244519.7
ENST00000490254.5
ENST00000487272.1
butyrophilin subfamily 3 member A3
chr5_-_95822711 0.18 ENST00000512469.2
ENST00000379979.8
ENST00000505427.1
ENST00000508780.5
ENST00000237858.11
glutaredoxin
chr17_+_6756035 0.18 ENST00000361842.8
ENST00000574907.5
XIAP associated factor 1
chr10_+_89301932 0.18 ENST00000371826.4
ENST00000679755.1
interferon induced protein with tetratricopeptide repeats 2
chr4_-_73982019 0.18 ENST00000296029.4
platelet factor 4
chr7_-_93148345 0.17 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chr11_-_57567617 0.17 ENST00000287156.9
ubiquitin conjugating enzyme E2 L6
chr7_-_122886439 0.16 ENST00000412584.6
ENST00000449022.7
calcium dependent secretion activator 2
chr2_-_162318129 0.16 ENST00000679938.1
interferon induced with helicase C domain 1
chr19_+_49474561 0.16 ENST00000594009.5
ENST00000595510.1
ENST00000595815.1
fms related receptor tyrosine kinase 3 ligand
novel transcript
chr3_+_187368367 0.16 ENST00000259030.3
receptor transporter protein 4
chr19_+_49474208 0.15 ENST00000597551.6
ENST00000596435.5
ENST00000204637.6
ENST00000600429.5
fms related receptor tyrosine kinase 3 ligand
chr2_-_118847638 0.15 ENST00000295206.7
engrailed homeobox 1
chr2_-_189179754 0.15 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr12_-_4649043 0.15 ENST00000545990.6
ENST00000228850.6
A-kinase anchoring protein 3
chr17_-_42112674 0.14 ENST00000251642.8
ENST00000591220.5
DExH-box helicase 58
chr12_+_133037476 0.14 ENST00000540031.5
ENST00000539354.6
ENST00000536123.5
zinc finger protein 84
chr19_+_17405685 0.14 ENST00000646744.1
ENST00000635536.2
ENST00000635060.2
ENST00000634291.2
ENST00000645298.1
ENST00000528911.5
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chr12_+_133037533 0.14 ENST00000327668.11
zinc finger protein 84
chr12_+_133037276 0.14 ENST00000392319.6
ENST00000543758.5
zinc finger protein 84
chr4_-_155953851 0.13 ENST00000679136.1
ENST00000433477.4
ENST00000679996.1
ENST00000680741.1
ENST00000680553.1
ENST00000679942.1
cathepsin O
chr19_+_10086305 0.13 ENST00000253110.16
ENST00000591813.5
shiftless antiviral inhibitor of ribosomal frameshifting
chr20_+_408147 0.12 ENST00000441733.5
ENST00000353660.7
RANBP2-type and C3HC4-type zinc finger containing 1
chr6_-_3751703 0.12 ENST00000380283.5
PX domain containing 1
chr1_-_177970213 0.11 ENST00000464631.6
SEC16 homolog B, endoplasmic reticulum export factor
chr2_+_201116143 0.11 ENST00000443227.5
ENST00000309955.8
ENST00000341222.10
ENST00000341582.10
CASP8 and FADD like apoptosis regulator
chr3_+_122680802 0.11 ENST00000474629.7
poly(ADP-ribose) polymerase family member 14
chr7_+_143132069 0.11 ENST00000291009.4
prolactin induced protein
chr9_+_92325910 0.11 ENST00000375587.8
ENST00000618653.1
centromere protein P
chr6_+_26402237 0.11 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
butyrophilin subfamily 3 member A1
chr5_+_141359970 0.10 ENST00000522605.2
ENST00000622527.1
protocadherin gamma subfamily B, 2
chr1_+_210328894 0.10 ENST00000261458.8
ENST00000537898.5
ENST00000545154.5
hedgehog acyltransferase
chr1_+_210329294 0.10 ENST00000367010.5
hedgehog acyltransferase
chr19_+_17405734 0.10 ENST00000635572.1
ENST00000634675.1
ENST00000634813.1
ENST00000647283.1
ENST00000635435.2
ENST00000634731.2
ENST00000635339.1
ENST00000528604.5
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chr1_-_147172456 0.10 ENST00000254101.4
protein kinase AMP-activated non-catalytic subunit beta 2
chr16_+_66934439 0.10 ENST00000417689.6
ENST00000561697.5
carboxylesterase 2
chr1_-_182589239 0.09 ENST00000367559.7
ENST00000539397.1
ribonuclease L
chr7_-_93117956 0.09 ENST00000446617.1
ENST00000379958.3
ENST00000620985.4
sterile alpha motif domain containing 9
chr22_+_36253071 0.09 ENST00000422706.5
ENST00000426053.5
ENST00000319136.8
apolipoprotein L1
chr20_-_49278034 0.08 ENST00000371744.5
ENST00000396105.6
ENST00000371752.5
zinc finger NFX1-type containing 1
chr10_-_100286341 0.08 ENST00000441611.5
ENST00000614731.4
biogenesis of lysosomal organelles complex 1 subunit 2
chr1_+_236394268 0.08 ENST00000334232.9
EDAR associated death domain
chr10_-_100286660 0.08 ENST00000370372.7
biogenesis of lysosomal organelles complex 1 subunit 2
chr2_+_201116238 0.08 ENST00000342795.9
CASP8 and FADD like apoptosis regulator
chr10_-_22003678 0.07 ENST00000376980.8
DnaJ heat shock protein family (Hsp40) member C1
chr22_+_36253124 0.07 ENST00000438034.5
ENST00000427990.5
ENST00000397278.8
ENST00000397279.8
ENST00000433768.5
apolipoprotein L1
chr14_+_24136152 0.07 ENST00000559123.5
ENST00000206451.11
ENST00000382708.7
ENST00000561435.5
proteasome activator subunit 1
chr1_-_161045961 0.07 ENST00000368021.7
upstream transcription factor 1
chr2_-_162318613 0.07 ENST00000649979.2
ENST00000421365.2
interferon induced with helicase C domain 1
chr3_+_51943244 0.07 ENST00000498510.2
poly(ADP-ribose) polymerase family member 3
chr1_-_161069857 0.07 ENST00000368013.8
Rho GTPase activating protein 30
chr1_-_161069962 0.07 ENST00000368015.1
Rho GTPase activating protein 30
chr1_+_20633450 0.06 ENST00000321556.5
PTEN induced kinase 1
chr8_+_39913881 0.06 ENST00000518237.6
indoleamine 2,3-dioxygenase 1
chr9_-_94640130 0.06 ENST00000414122.1
fructose-bisphosphatase 1
chr20_-_63216102 0.06 ENST00000370339.8
ENST00000370334.4
YTH N6-methyladenosine RNA binding protein 1
chr12_+_6452024 0.06 ENST00000266556.8
ENST00000544021.5
TAP binding protein like
chr2_-_144517663 0.05 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
zinc finger E-box binding homeobox 2
chr22_+_18150162 0.05 ENST00000215794.8
ubiquitin specific peptidase 18
chr2_-_174764407 0.05 ENST00000409219.5
ENST00000409542.5
cholinergic receptor nicotinic alpha 1 subunit
chr2_-_151261839 0.05 ENST00000331426.6
RNA binding motif protein 43
chr6_-_36387654 0.05 ENST00000340181.9
ETS variant transcription factor 7
chrX_+_77899440 0.05 ENST00000373335.4
ENST00000475465.1
ENST00000650309.2
ENST00000647835.1
cytochrome c oxidase subunit 7B
chr7_+_101085464 0.05 ENST00000306085.11
ENST00000412507.1
tripartite motif containing 56
chr6_-_36387736 0.05 ENST00000373737.8
ENST00000373738.4
ENST00000538992.3
ENST00000615781.4
ENST00000620358.4
ETS variant transcription factor 7
chr20_-_20052389 0.05 ENST00000536226.2
crooked neck pre-mRNA splicing factor 1
chr14_-_20413420 0.05 ENST00000556935.5
ENST00000556549.1
ENST00000262715.10
telomerase associated protein 1
chr22_+_39040857 0.05 ENST00000381565.2
ENST00000308521.10
apolipoprotein B mRNA editing enzyme catalytic subunit 3F
chr5_-_43040311 0.05 ENST00000616064.2
annexin A2 receptor
chr20_-_25058115 0.05 ENST00000323482.9
acyl-CoA synthetase short chain family member 1
chr10_+_113679523 0.04 ENST00000345633.8
ENST00000614447.4
ENST00000369321.6
caspase 7
chr2_+_218260991 0.04 ENST00000522678.5
ENST00000519574.2
ENST00000521462.1
G protein-coupled bile acid receptor 1
chr20_-_25058168 0.04 ENST00000432802.6
acyl-CoA synthetase short chain family member 1
chr6_+_26365176 0.04 ENST00000377708.7
butyrophilin subfamily 3 member A2
chr6_+_26402289 0.04 ENST00000414912.2
butyrophilin subfamily 3 member A1
chr6_+_26365215 0.04 ENST00000527422.5
ENST00000356386.6
ENST00000396948.5
butyrophilin subfamily 3 member A2
chr21_+_41420515 0.04 ENST00000398600.6
ENST00000679626.1
MX dynamin like GTPase 1
chr2_+_201116793 0.04 ENST00000441224.5
CASP8 and FADD like apoptosis regulator
chr22_-_36239517 0.03 ENST00000358502.10
ENST00000451256.6
apolipoprotein L2
chr1_+_151156627 0.03 ENST00000368910.4
TNF alpha induced protein 8 like 2
chr20_+_408278 0.03 ENST00000356286.10
ENST00000382181.2
ENST00000400247.3
RANBP2-type and C3HC4-type zinc finger containing 1
chr8_-_143986425 0.03 ENST00000313059.9
ENST00000524918.5
ENST00000313028.12
ENST00000525773.5
poly(ADP-ribose) polymerase family member 10
chr6_+_26365159 0.03 ENST00000532865.5
ENST00000396934.7
ENST00000508906.6
ENST00000530653.5
ENST00000527417.5
butyrophilin subfamily 3 member A2
chr2_-_230219944 0.03 ENST00000455674.2
ENST00000392048.7
ENST00000258381.11
ENST00000358662.9
ENST00000258382.10
SP110 nuclear body protein
chr1_+_149475045 0.03 ENST00000651566.2
NBPF member 19
chr12_+_12070932 0.03 ENST00000308721.9
BCL2 like 14
chr10_+_113679839 0.03 ENST00000369318.8
ENST00000369315.5
caspase 7
chr7_-_139109337 0.03 ENST00000464606.5
zinc finger CCCH-type containing, antiviral 1
chr2_+_69013170 0.03 ENST00000303714.9
ANTXR cell adhesion molecule 1
chr22_+_39077264 0.03 ENST00000407997.4
apolipoprotein B mRNA editing enzyme catalytic subunit 3G
chr20_-_37158904 0.03 ENST00000417458.5
maestro heat like repeat family member 8
chr1_+_151156659 0.03 ENST00000602841.5
sodium channel modifier 1
chr1_+_25272527 0.03 ENST00000342055.9
ENST00000357542.8
ENST00000417538.6
ENST00000423810.6
ENST00000568195.5
Rh blood group D antigen
chr12_+_12071396 0.03 ENST00000396367.5
ENST00000266434.8
BCL2 like 14
chr20_-_21514046 0.03 ENST00000377142.5
NK2 homeobox 2
chr14_-_75051426 0.03 ENST00000556257.5
ENST00000355774.7
ENST00000557648.1
ENST00000553263.1
ENST00000380968.6
mutL homolog 3
chr2_-_230219902 0.03 ENST00000409815.6
SP110 nuclear body protein
chr9_-_32526185 0.03 ENST00000379883.3
ENST00000379868.6
ENST00000679859.1
DExD/H-box helicase 58
chr16_+_75647757 0.02 ENST00000300086.5
ENST00000653858.1
TERF2 interacting protein
chr16_-_29863117 0.02 ENST00000566113.5
ENST00000569956.5
ENST00000570016.5
ENST00000219789.11
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr6_+_28225257 0.02 ENST00000531981.5
ENST00000425468.6
ENST00000252207.10
ENST00000531979.5
ENST00000527436.5
zinc finger and SCAN domain containing 9
chr14_-_70416994 0.02 ENST00000621525.4
ENST00000256366.6
SYNJ2BP-COX16 readthrough
synaptojanin 2 binding protein
chr3_+_155870623 0.02 ENST00000295920.7
ENST00000496455.7
guanine monophosphate synthase
chr4_-_168480477 0.02 ENST00000514748.5
ENST00000512371.1
ENST00000505890.5
ENST00000682922.1
ENST00000511577.5
DExD/H-box 60 like
chr4_-_168318743 0.02 ENST00000393743.8
DExD/H-box helicase 60
chr5_+_140691591 0.02 ENST00000508522.5
ENST00000448069.2
histidyl-tRNA synthetase 2, mitochondrial
chr11_+_124865425 0.02 ENST00000397801.6
roundabout guidance receptor 3
chr14_-_24146596 0.02 ENST00000560410.5
ENST00000216802.10
ENST00000615264.4
ENST00000630027.1
proteasome activator subunit 2
chr4_-_76213520 0.02 ENST00000640634.1
scavenger receptor class B member 2
chr4_-_168318770 0.02 ENST00000680771.1
ENST00000514995.2
DExD/H-box helicase 60
chr16_-_11256192 0.02 ENST00000644787.1
ENST00000332029.4
suppressor of cytokine signaling 1
chr1_+_25272439 0.02 ENST00000648012.1
Rh blood group D antigen
chr4_-_76213817 0.02 ENST00000264896.8
ENST00000640640.1
ENST00000640957.1
scavenger receptor class B member 2
chr6_-_121334450 0.02 ENST00000398212.7
TBC1 domain family member 32
chr11_-_124320197 0.02 ENST00000624618.2
olfactory receptor family 8 subfamily D member 2
chr10_+_35127295 0.02 ENST00000489321.5
ENST00000427847.6
ENST00000374728.7
ENST00000345491.7
ENST00000487132.5
cAMP responsive element modulator
chr2_-_166494232 0.02 ENST00000441411.2
ENST00000643258.1
ENST00000419992.6
sodium voltage-gated channel alpha subunit 7
chr1_-_177969907 0.02 ENST00000308284.10
SEC16 homolog B, endoplasmic reticulum export factor
chr19_-_47232649 0.02 ENST00000449228.5
ENST00000300880.11
ENST00000341983.8
BCL2 binding component 3
chr6_-_132763424 0.02 ENST00000532012.1
ENST00000525270.5
ENST00000530536.5
ENST00000524919.5
vanin 2
chr2_-_73642413 0.02 ENST00000272425.4
N-acetyltransferase 8 (putative)
chr22_+_35648438 0.02 ENST00000409652.5
apolipoprotein L6
chr1_-_161044941 0.02 ENST00000368020.5
upstream transcription factor 1
chr14_+_77324557 0.01 ENST00000553586.5
ENST00000555583.1
glutathione S-transferase zeta 1
chr1_+_25272492 0.01 ENST00000454452.6
Rh blood group D antigen
chr1_-_25420792 0.01 ENST00000346452.8
ENST00000340849.8
ENST00000349438.8
ENST00000413854.5
ENST00000294413.13
Rh blood group CcEe antigens
chr6_-_30213379 0.01 ENST00000418026.1
ENST00000454678.7
ENST00000416596.5
ENST00000453195.5
tripartite motif containing 26
chr14_-_24146314 0.01 ENST00000559056.5
proteasome activator subunit 2
chrX_-_110318062 0.01 ENST00000372059.6
ENST00000262844.10
AMMECR nuclear protein 1
chr20_+_408030 0.01 ENST00000640614.1
ENST00000475269.5
RANBP2-type and C3HC4-type zinc finger containing 1
chr3_-_122564253 0.01 ENST00000492382.5
ENST00000682323.1
ENST00000462315.5
poly(ADP-ribose) polymerase family member 9
chr18_+_24014733 0.01 ENST00000317571.8
tetratricopeptide repeat domain 39C
chr1_-_89198868 0.01 ENST00000355754.7
guanylate binding protein 4
chr17_-_35880350 0.01 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
C-C motif chemokine ligand 5
chr4_-_76213589 0.01 ENST00000638603.1
ENST00000452464.6
scavenger receptor class B member 2
chr20_+_20052506 0.01 ENST00000340348.10
ENST00000245957.10
ENST00000674269.1
ENST00000377306.5
ENST00000377303.6
ENST00000475466.5
cilia and flagella associated protein 61
chr2_+_99154955 0.01 ENST00000393471.2
ENST00000393473.6
ENST00000651691.1
ENST00000449211.1
ENST00000434566.5
ENST00000410042.1
lipoyltransferase 1
novel LIPT1-MRPL30 readthrough
chr9_-_87974487 0.01 ENST00000375871.8
ENST00000605159.5
ENST00000325303.9
ENST00000336654.9
cyclin dependent kinase 20
chr9_-_137188540 0.01 ENST00000323927.3
anaphase promoting complex subunit 2
chr8_-_23069012 0.01 ENST00000347739.3
ENST00000276431.9
TNF receptor superfamily member 10b
chr11_+_5624987 0.01 ENST00000429814.3
tripartite motif containing 34
chr11_+_32091065 0.01 ENST00000054950.4
reticulocalbin 1
chr20_+_62804794 0.01 ENST00000290291.10
opioid growth factor receptor
chr15_-_44711306 0.01 ENST00000682850.1
PAT1 homolog 2
chr20_-_35284715 0.01 ENST00000374436.7
ENST00000675032.1
eukaryotic translation initiation factor 6
chr1_+_112674722 0.01 ENST00000357443.2
Mov10 RISC complex RNA helicase
chrX_+_57286680 0.01 ENST00000374900.5
fatty acid amide hydrolase 2
chr17_+_42289213 0.01 ENST00000677301.1
signal transducer and activator of transcription 5A
chr10_-_48493641 0.00 ENST00000417247.6
Rho GTPase activating protein 22
chr1_+_112674649 0.00 ENST00000369644.5
Mov10 RISC complex RNA helicase
chr15_+_56918763 0.00 ENST00000557843.5
transcription factor 12
chr9_-_87974667 0.00 ENST00000375883.7
cyclin dependent kinase 20
chr5_-_136365476 0.00 ENST00000378459.7
ENST00000502753.4
ENST00000513104.6
ENST00000352189.8
transient receptor potential cation channel subfamily C member 7
chr15_+_64136330 0.00 ENST00000560861.1
sorting nexin 1
chr20_-_35284745 0.00 ENST00000374443.7
ENST00000374450.8
eukaryotic translation initiation factor 6
chr12_-_48570046 0.00 ENST00000301046.6
ENST00000549817.1
lactalbumin alpha
chr17_-_65056659 0.00 ENST00000439174.7
G protein subunit alpha 13
chr7_-_139109702 0.00 ENST00000471652.1
ENST00000242351.10
zinc finger CCCH-type containing, antiviral 1
chr19_+_49929196 0.00 ENST00000423777.7
ENST00000600336.1
ENST00000597227.5
activating transcription factor 5
chr12_-_98894830 0.00 ENST00000549797.5
ENST00000333732.11
ENST00000341752.11
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_+_129096144 0.00 ENST00000425929.6
ENST00000508622.1
chromosome 4 open reading frame 33
chr3_+_63911929 0.00 ENST00000487717.5
ataxin 7
chr6_-_36387566 0.00 ENST00000339796.9
ENST00000627426.2
ETS variant transcription factor 7
chr1_+_150508074 0.00 ENST00000369049.8
extracellular matrix protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.3 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.2 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.8 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.4 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0019413 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:0045653 negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.5 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:1903383 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.0 0.2 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.0 0.1 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle