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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for IRX2

Z-value: 1.06

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Transcription factors associated with IRX2

Gene Symbol Gene ID Gene Info
IRX2
ENSG00000170561.13 iroquois homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX2hg38_v1_chr5_-_2751648_27516680.621.0e-01Click!

Activity profile of IRX2 motif

Sorted Z-values of IRX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_98268186 1.41 ENST00000260702.4
LOXL4
lysyl oxidase like 4
chr16_+_68644988 1.08 ENST00000429102.6
CDH3
cadherin 3
chr17_-_3691887 0.89 ENST00000552050.5
P2RX5
purinergic receptor P2X 5
chr5_+_36608146 0.77 ENST00000381918.4
ENST00000513646.1
SLC1A3
solute carrier family 1 member 3
chr11_-_7830840 0.75 ENST00000641167.1
OR5P3
olfactory receptor family 5 subfamily P member 3
chr3_+_122325237 0.75 ENST00000264474.4
ENST00000479204.1
CSTA
cystatin A
chr3_-_112846856 0.66 ENST00000488794.5
CD200R1L
CD200 receptor 1 like
chr6_-_136525961 0.64 ENST00000438100.6
MAP7
microtubule associated protein 7
chr6_-_136526177 0.63 ENST00000617204.4
MAP7
microtubule associated protein 7
chr6_-_136526472 0.58 ENST00000454590.5
ENST00000432797.6
MAP7
microtubule associated protein 7
chr6_-_136526654 0.54 ENST00000611373.1
MAP7
microtubule associated protein 7
chr4_-_22443110 0.53 ENST00000508133.5
ADGRA3
adhesion G protein-coupled receptor A3
chr9_-_137302264 0.50 ENST00000356628.4
NRARP
NOTCH regulated ankyrin repeat protein
chr8_-_85341705 0.48 ENST00000517618.5
CA1
carbonic anhydrase 1
chr16_+_82035245 0.45 ENST00000199936.9
HSD17B2
hydroxysteroid 17-beta dehydrogenase 2
chr11_+_62880863 0.44 ENST00000680297.1
SLC3A2
solute carrier family 3 member 2
chr11_+_62880885 0.44 ENST00000541372.1
ENST00000539458.1
ENST00000338663.12
ENST00000681232.1
ENST00000681657.1
SLC3A2
solute carrier family 3 member 2
chrX_+_136536099 0.42 ENST00000440515.5
ENST00000456412.1
VGLL1
vestigial like family member 1
chr4_+_87975667 0.42 ENST00000237623.11
ENST00000682655.1
ENST00000508233.6
ENST00000360804.4
ENST00000395080.8
SPP1
secreted phosphoprotein 1
chr1_+_31410164 0.40 ENST00000536859.5
SERINC2
serine incorporator 2
chr17_-_27800524 0.39 ENST00000313735.11
NOS2
nitric oxide synthase 2
chr18_-_55403682 0.38 ENST00000564228.5
ENST00000630828.2
TCF4
transcription factor 4
chr5_+_147878703 0.36 ENST00000296694.5
SCGB3A2
secretoglobin family 3A member 2
chr10_+_125973373 0.30 ENST00000417114.5
ENST00000445510.5
ENST00000368691.5
FANK1
fibronectin type III and ankyrin repeat domains 1
chr15_-_44194407 0.29 ENST00000484674.5
FRMD5
FERM domain containing 5
chr8_-_85341659 0.29 ENST00000522389.5
CA1
carbonic anhydrase 1
chr10_-_59362584 0.28 ENST00000618427.4
ENST00000611933.4
FAM13C
family with sequence similarity 13 member C
chr12_+_8992029 0.26 ENST00000543895.1
KLRG1
killer cell lectin like receptor G1
chr6_-_53148822 0.25 ENST00000259803.8
GCM1
glial cells missing transcription factor 1
chr7_+_95485898 0.24 ENST00000428113.5
ASB4
ankyrin repeat and SOCS box containing 4
chr18_-_36122110 0.24 ENST00000586829.1
SLC39A6
solute carrier family 39 member 6
chr7_-_105691637 0.22 ENST00000472195.1
ATXN7L1
ataxin 7 like 1
chr7_+_72925075 0.22 ENST00000434423.5
POM121
POM121 transmembrane nucleoporin
chr21_+_42403856 0.20 ENST00000291535.11
UBASH3A
ubiquitin associated and SH3 domain containing A
chr11_+_60280577 0.20 ENST00000679988.1
MS4A4A
membrane spanning 4-domains A4A
chr2_+_158795309 0.20 ENST00000309950.8
ENST00000621326.4
ENST00000409042.5
DAPL1
death associated protein like 1
chr5_-_35047935 0.20 ENST00000510428.1
ENST00000231420.11
AGXT2
alanine--glyoxylate aminotransferase 2
chr11_+_33016106 0.20 ENST00000311388.7
DEPDC7
DEP domain containing 7
chr13_+_102656933 0.19 ENST00000650757.1
TPP2
tripeptidyl peptidase 2
chr7_+_144003929 0.19 ENST00000408922.3
OR6B1
olfactory receptor family 6 subfamily B member 1
chr8_+_97887903 0.18 ENST00000520016.5
MATN2
matrilin 2
chr4_-_152411734 0.18 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7
chr12_+_53097656 0.18 ENST00000301464.4
IGFBP6
insulin like growth factor binding protein 6
chr16_+_56865202 0.17 ENST00000566786.5
ENST00000438926.6
ENST00000563236.6
ENST00000262502.5
SLC12A3
solute carrier family 12 member 3
chr1_-_206921867 0.17 ENST00000628511.2
ENST00000367091.8
FCMR
Fc fragment of IgM receptor
chr6_+_24774925 0.17 ENST00000356509.7
ENST00000230056.8
GMNN
geminin DNA replication inhibitor
chr18_+_22933819 0.15 ENST00000399722.6
ENST00000399725.6
ENST00000399721.6
RBBP8
RB binding protein 8, endonuclease
chr10_-_59362460 0.15 ENST00000422313.6
ENST00000435852.6
ENST00000614220.4
ENST00000618804.5
ENST00000621119.4
FAM13C
family with sequence similarity 13 member C
chr6_+_143864458 0.15 ENST00000237275.9
ZC2HC1B
zinc finger C2HC-type containing 1B
chr1_-_206921987 0.14 ENST00000530505.1
ENST00000442471.4
FCMR
Fc fragment of IgM receptor
chrX_-_71111448 0.14 ENST00000456850.6
ENST00000473378.1
ENST00000374202.7
ENST00000374188.7
IL2RG
interleukin 2 receptor subunit gamma
chr15_-_79971164 0.14 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2A1
BCL2 related protein A1
chr3_-_197260369 0.14 ENST00000658155.1
ENST00000453607.5
DLG1
discs large MAGUK scaffold protein 1
chr17_-_3433841 0.14 ENST00000248384.1
OR1E2
olfactory receptor family 1 subfamily E member 2
chr13_-_21459253 0.13 ENST00000400590.8
ENST00000382466.7
ENST00000415724.2
ENST00000542645.5
ZDHHC20
zinc finger DHHC-type palmitoyltransferase 20
chr8_+_93754844 0.13 ENST00000684064.1
ENST00000498673.5
ENST00000518319.5
TMEM67
transmembrane protein 67
chr21_-_30166782 0.13 ENST00000286808.5
CLDN17
claudin 17
chr3_+_133124807 0.13 ENST00000508711.5
TMEM108
transmembrane protein 108
chr11_+_6845683 0.13 ENST00000299454.5
OR10A5
olfactory receptor family 10 subfamily A member 5
chr4_+_56505782 0.13 ENST00000640821.3
ARL9
ADP ribosylation factor like GTPase 9
chr14_+_75069577 0.12 ENST00000238686.8
ZC2HC1C
zinc finger C2HC-type containing 1C
chr1_-_156728388 0.12 ENST00000313146.10
ISG20L2
interferon stimulated exonuclease gene 20 like 2
chr16_-_71289609 0.12 ENST00000338099.9
ENST00000563876.1
CMTR2
cap methyltransferase 2
chr6_+_4706133 0.11 ENST00000328908.9
CDYL
chromodomain Y like
chr11_+_111255982 0.11 ENST00000637637.1
C11orf53
chromosome 11 open reading frame 53
chrX_-_100874351 0.11 ENST00000372966.8
NOX1
NADPH oxidase 1
chr7_+_16661182 0.11 ENST00000446596.5
ENST00000452975.6
ENST00000438834.5
BZW2
basic leucine zipper and W2 domains 2
chr6_-_31652678 0.11 ENST00000437771.5
ENST00000362049.10
ENST00000439687.6
ENST00000211379.9
ENST00000375964.11
ENST00000676571.1
ENST00000676615.1
BAG6
BAG cochaperone 6
chrX_-_119605870 0.11 ENST00000542113.3
NKRF
NFKB repressing factor
chr16_-_4351283 0.10 ENST00000318059.8
PAM16
presequence translocase associated motor 16
chr2_+_112721486 0.10 ENST00000327581.4
NT5DC4
5'-nucleotidase domain containing 4
chr4_-_38804783 0.10 ENST00000308979.7
ENST00000505940.1
ENST00000515861.5
TLR1
toll like receptor 1
chr8_+_30387064 0.10 ENST00000523115.5
ENST00000519647.5
RBPMS
RNA binding protein, mRNA processing factor
chr1_+_166989254 0.10 ENST00000367872.9
ENST00000447624.1
MAEL
maelstrom spermatogenic transposon silencer
chr5_-_83720813 0.10 ENST00000515590.1
ENST00000274341.9
HAPLN1
hyaluronan and proteoglycan link protein 1
chr1_+_166989089 0.10 ENST00000367870.6
MAEL
maelstrom spermatogenic transposon silencer
chr5_-_95081482 0.10 ENST00000312216.12
ENST00000512425.5
ENST00000505208.5
ENST00000429576.6
ENST00000508509.5
ENST00000510732.5
MCTP1
multiple C2 and transmembrane domain containing 1
chr7_+_95485934 0.09 ENST00000325885.6
ASB4
ankyrin repeat and SOCS box containing 4
chr5_-_72507354 0.09 ENST00000414109.2
ENST00000318442.6
ZNF366
zinc finger protein 366
chr4_-_149815826 0.09 ENST00000636793.2
ENST00000636414.1
IQCM
IQ motif containing M
chr1_-_173603041 0.09 ENST00000367714.4
SLC9C2
solute carrier family 9 member C2 (putative)
chrX_-_49186328 0.09 ENST00000599218.6
ENST00000376317.4
PRICKLE3
prickle planar cell polarity protein 3
chr16_+_81238682 0.09 ENST00000258168.7
ENST00000564552.1
BCO1
beta-carotene oxygenase 1
chr20_+_57561103 0.09 ENST00000319441.6
PCK1
phosphoenolpyruvate carboxykinase 1
chr17_+_7857695 0.09 ENST00000571846.5
CYB5D1
cytochrome b5 domain containing 1
chr4_-_127965930 0.09 ENST00000641447.1
ENST00000296468.8
ENST00000641134.1
ENST00000641147.1
ENST00000641178.1
MFSD8
major facilitator superfamily domain containing 8
chr3_-_194351290 0.09 ENST00000429275.1
ENST00000323830.4
CPN2
carboxypeptidase N subunit 2
chr14_+_75069632 0.09 ENST00000439583.2
ENST00000554763.2
ENST00000524913.3
ENST00000525046.2
ENST00000674086.1
ENST00000526130.2
ENST00000674094.1
ENST00000532198.2
ZC2HC1C
zinc finger C2HC-type containing 1C
chr3_-_122383218 0.09 ENST00000479899.5
ENST00000291458.9
ENST00000497726.5
MIX23
mitochondrial matrix import factor 23
chr2_+_48617798 0.08 ENST00000448460.5
ENST00000437125.5
ENST00000430487.6
GTF2A1L
general transcription factor IIA subunit 1 like
chr16_+_7332744 0.08 ENST00000436368.6
ENST00000311745.9
ENST00000340209.8
ENST00000620507.4
RBFOX1
RNA binding fox-1 homolog 1
chr2_+_27148997 0.08 ENST00000296096.6
TCF23
transcription factor 23
chr11_+_60280531 0.08 ENST00000532114.6
MS4A4A
membrane spanning 4-domains A4A
chrX_-_21658324 0.08 ENST00000379499.3
KLHL34
kelch like family member 34
chr8_+_80485611 0.08 ENST00000379091.8
ZBTB10
zinc finger and BTB domain containing 10
chr21_-_14658812 0.08 ENST00000647101.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr17_+_58169401 0.07 ENST00000641866.1
OR4D2
olfactory receptor family 4 subfamily D member 2
chr5_+_73813518 0.07 ENST00000296799.8
ARHGEF28
Rho guanine nucleotide exchange factor 28
chr17_+_7857987 0.07 ENST00000332439.5
CYB5D1
cytochrome b5 domain containing 1
chr3_-_185821092 0.07 ENST00000421047.3
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr10_+_99782628 0.07 ENST00000648689.1
ENST00000647814.1
ABCC2
ATP binding cassette subfamily C member 2
chr4_-_167234266 0.07 ENST00000511269.5
ENST00000506697.5
ENST00000512042.1
SPOCK3
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr14_-_64823148 0.07 ENST00000389722.7
SPTB
spectrin beta, erythrocytic
chr5_-_161546671 0.06 ENST00000517547.5
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr21_+_42403874 0.06 ENST00000319294.11
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr17_+_36064265 0.06 ENST00000616054.2
CCL18
C-C motif chemokine ligand 18
chr17_-_8152380 0.06 ENST00000317276.9
PER1
period circadian regulator 1
chr6_-_111605859 0.06 ENST00000651359.1
ENST00000650859.1
ENST00000359831.8
ENST00000368761.11
TRAF3IP2
TRAF3 interacting protein 2
chr7_-_150323489 0.06 ENST00000683684.1
ENST00000478393.5
ACTR3C
actin related protein 3C
chr6_-_159045104 0.06 ENST00000326965.7
TAGAP
T cell activation RhoGTPase activating protein
chr9_-_35812238 0.05 ENST00000396638.7
ENST00000340291.6
SPAG8
sperm associated antigen 8
chr1_+_204870831 0.05 ENST00000404076.5
ENST00000539706.6
NFASC
neurofascin
chr7_+_69967464 0.05 ENST00000664521.1
AUTS2
activator of transcription and developmental regulator AUTS2
chr1_+_15756659 0.05 ENST00000375771.5
FBLIM1
filamin binding LIM protein 1
chr15_-_58279245 0.05 ENST00000558231.5
ALDH1A2
aldehyde dehydrogenase 1 family member A2
chr1_+_152719522 0.05 ENST00000368775.3
C1orf68
chromosome 1 open reading frame 68
chr14_-_64942783 0.05 ENST00000612794.1
GPX2
glutathione peroxidase 2
chr6_+_27957241 0.05 ENST00000244623.1
OR2B6
olfactory receptor family 2 subfamily B member 6
chr2_+_27628996 0.05 ENST00000616939.4
ENST00000264718.7
ENST00000610189.2
GPN1
GPN-loop GTPase 1
chr17_-_40799939 0.05 ENST00000306658.8
KRT28
keratin 28
chr12_-_102120065 0.05 ENST00000552283.6
ENST00000551744.2
NUP37
nucleoporin 37
chr2_+_233729042 0.05 ENST00000482026.6
UGT1A3
UDP glucuronosyltransferase family 1 member A3
chr1_-_157841800 0.05 ENST00000368174.5
CD5L
CD5 molecule like
chr8_+_24294107 0.05 ENST00000437154.6
ADAM28
ADAM metallopeptidase domain 28
chr8_-_81447428 0.04 ENST00000256103.3
ENST00000519260.1
PMP2
peripheral myelin protein 2
chr6_-_159044980 0.04 ENST00000367066.8
TAGAP
T cell activation RhoGTPase activating protein
chr1_-_112618204 0.04 ENST00000369664.1
ST7L
suppression of tumorigenicity 7 like
chr11_+_60056653 0.04 ENST00000278865.8
MS4A3
membrane spanning 4-domains A3
chr5_-_180815528 0.04 ENST00000333055.8
MGAT1
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chr1_+_215573775 0.04 ENST00000448333.1
KCTD3
potassium channel tetramerization domain containing 3
chr17_-_5419647 0.03 ENST00000573584.6
NUP88
nucleoporin 88
chr1_-_173824322 0.03 ENST00000356198.6
CENPL
centromere protein L
chr6_-_27873525 0.03 ENST00000618305.2
H4C13
H4 clustered histone 13
chr4_-_167234426 0.03 ENST00000541354.5
ENST00000509854.5
ENST00000512681.5
ENST00000357545.9
ENST00000510741.5
ENST00000510403.5
SPOCK3
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr1_+_67207614 0.03 ENST00000425614.3
IL23R
interleukin 23 receptor
chr16_-_74607088 0.03 ENST00000565260.1
ENST00000447066.6
ENST00000205061.9
ENST00000422840.7
ENST00000627032.2
GLG1
golgi glycoprotein 1
chr16_+_58392462 0.03 ENST00000318129.6
GINS3
GINS complex subunit 3
chr7_+_107044689 0.03 ENST00000265717.5
PRKAR2B
protein kinase cAMP-dependent type II regulatory subunit beta
chrX_-_100874209 0.03 ENST00000372964.5
ENST00000217885.5
NOX1
NADPH oxidase 1
chr14_+_23321446 0.03 ENST00000216727.9
ENST00000397276.6
PABPN1
poly(A) binding protein nuclear 1
chr6_+_13272709 0.03 ENST00000379335.8
PHACTR1
phosphatase and actin regulator 1
chr9_-_35079923 0.02 ENST00000378643.8
ENST00000448890.1
FANCG
FA complementation group G
chr8_+_7495892 0.02 ENST00000355602.3
DEFB107B
defensin beta 107B
chrX_-_149595314 0.02 ENST00000598963.3
HSFX2
heat shock transcription factor family, X-linked 2
chr13_-_46105009 0.02 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
CPB2
carboxypeptidase B2
chr8_+_24294044 0.02 ENST00000265769.9
ADAM28
ADAM metallopeptidase domain 28
chr5_-_161546708 0.02 ENST00000393959.6
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr9_+_137086857 0.02 ENST00000682881.1
ENST00000683324.1
ENST00000542372.2
ENST00000683355.1
ENST00000682117.1
ENST00000682212.1
ENST00000684144.1
ENST00000683987.1
ENST00000371589.9
ENST00000535144.6
ENST00000475449.7
ENST00000684759.1
MAN1B1
mannosidase alpha class 1B member 1
chrX_+_155997581 0.02 ENST00000244174.10
IL9R
interleukin 9 receptor
chr4_+_157220691 0.02 ENST00000509417.5
ENST00000645636.1
ENST00000296526.12
ENST00000264426.14
GRIA2
glutamate ionotropic receptor AMPA type subunit 2
chrX_+_155997706 0.02 ENST00000369423.7
IL9R
interleukin 9 receptor
chr4_-_167234579 0.02 ENST00000502330.5
ENST00000357154.7
ENST00000421836.6
SPOCK3
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr1_-_158554405 0.02 ENST00000641282.1
ENST00000641622.1
OR6Y1
olfactory receptor family 6 subfamily Y member 1
chr13_-_23433676 0.02 ENST00000682547.1
ENST00000455470.6
ENST00000382292.9
SACS
sacsin molecular chaperone
chr14_-_105845677 0.02 ENST00000390556.6
IGHD
immunoglobulin heavy constant delta
chr1_-_149812359 0.02 ENST00000369167.2
ENST00000545683.1
H2BC18
H2B clustered histone 18
chr14_-_100375333 0.02 ENST00000557297.5
ENST00000555813.5
ENST00000392882.7
ENST00000557135.5
ENST00000556698.5
ENST00000554509.5
ENST00000555410.5
WARS1
tryptophanyl-tRNA synthetase 1
chr16_+_67570741 0.01 ENST00000644753.1
ENST00000642819.1
ENST00000645306.1
CTCF
CCCTC-binding factor
chr17_+_35844077 0.01 ENST00000604694.1
TAF15
TATA-box binding protein associated factor 15
chr12_-_123272234 0.01 ENST00000544658.5
CDK2AP1
cyclin dependent kinase 2 associated protein 1
chr16_+_58392391 0.01 ENST00000426538.6
ENST00000328514.11
GINS3
GINS complex subunit 3
chr2_-_165204042 0.01 ENST00000283254.12
ENST00000453007.1
SCN3A
sodium voltage-gated channel alpha subunit 3
chr4_+_113292925 0.01 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ANK2
ankyrin 2
chr6_+_29396555 0.01 ENST00000623183.1
OR12D2
olfactory receptor family 12 subfamily D member 2
chr4_-_70839343 0.01 ENST00000514161.5
ENST00000499044.6
GRSF1
G-rich RNA sequence binding factor 1
chr2_-_46617020 0.01 ENST00000474980.1
ENST00000281382.11
ENST00000306465.8
PIGF
phosphatidylinositol glycan anchor biosynthesis class F
chr7_-_83649097 0.01 ENST00000643230.2
SEMA3E
semaphorin 3E
chr10_-_95069489 0.01 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
CYP2C8
cytochrome P450 family 2 subfamily C member 8
chr19_-_39846329 0.01 ENST00000599134.1
ENST00000597634.5
ENST00000598417.5
ENST00000601274.5
ENST00000594309.5
ENST00000221801.8
FBL
fibrillarin
chr2_+_170178136 0.01 ENST00000409044.7
ENST00000408978.9
MYO3B
myosin IIIB
chr1_+_162381703 0.01 ENST00000458626.4
C1orf226
chromosome 1 open reading frame 226
chr20_-_31390483 0.01 ENST00000376315.2
DEFB119
defensin beta 119
chr4_+_113292838 0.00 ENST00000672411.1
ENST00000673231.1
ANK2
ankyrin 2
chr14_-_68793055 0.00 ENST00000439696.3
ZFP36L1
ZFP36 ring finger protein like 1
chr2_-_70293438 0.00 ENST00000482975.6
ENST00000438261.5
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr4_+_118685373 0.00 ENST00000388822.10
ENST00000508801.1
METTL14
methyltransferase like 14
chr5_-_39364484 0.00 ENST00000263408.5
C9
complement C9
chr13_-_40982880 0.00 ENST00000635415.1
ELF1
E74 like ETS transcription factor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912) negative regulation of hair follicle maturation(GO:0048817) regulation of melanosome transport(GO:1902908)
0.1 0.9 GO:0060356 leucine import(GO:0060356)
0.1 0.4 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.4 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.8 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.3 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.5 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.1 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.0 0.2 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.1 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.2 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.1 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.0 0.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:1904327 tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227) positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.9 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0016119 carotene metabolic process(GO:0016119)
0.0 0.1 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.0 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771) interleukin-2-mediated signaling pathway(GO:0038110)
0.0 2.1 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0030849 autosome(GO:0030849)
0.0 0.9 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.9 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.8 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 1.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.8 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism