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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for IRX6_IRX4

Z-value: 0.08

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Transcription factors associated with IRX6_IRX4

Gene Symbol Gene ID Gene Info
ENSG00000159387.8 iroquois homeobox 6
ENSG00000113430.10 iroquois homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX4hg38_v1_chr5_-_1886938_1886984,
hg38_v1_chr5_-_1882902_1882932
0.363.8e-01Click!

Activity profile of IRX6_IRX4 motif

Sorted Z-values of IRX6_IRX4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_36608146 0.11 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr3_-_27456743 0.10 ENST00000295736.9
ENST00000428386.5
ENST00000428179.1
solute carrier family 4 member 7
chr13_-_46142834 0.09 ENST00000674665.1
lymphocyte cytosolic protein 1
chr14_-_23154422 0.09 ENST00000422941.6
solute carrier family 7 member 8
chr14_-_23155302 0.08 ENST00000529705.6
solute carrier family 7 member 8
chr14_-_23154369 0.07 ENST00000453702.5
solute carrier family 7 member 8
chr4_+_40193642 0.07 ENST00000617441.4
ENST00000503941.5
ras homolog family member H
chr1_+_220094086 0.06 ENST00000366922.3
isoleucyl-tRNA synthetase 2, mitochondrial
chr11_+_89924064 0.04 ENST00000623787.3
tripartite motif containing 49D2
chr21_-_32813679 0.04 ENST00000487113.1
ENST00000382373.4
chromosome 21 open reading frame 62
chr4_+_70592295 0.04 ENST00000449493.2
ameloblastin
chr4_-_103198371 0.04 ENST00000611174.4
ENST00000380026.8
centromere protein E
chr21_-_32813695 0.04 ENST00000479548.2
ENST00000490358.5
chromosome 21 open reading frame 62
chr17_-_31314040 0.04 ENST00000330927.5
ecotropic viral integration site 2B
chr4_-_103198331 0.04 ENST00000265148.9
ENST00000514974.1
centromere protein E
chr7_-_16804987 0.03 ENST00000401412.5
ENST00000419304.7
anterior gradient 2, protein disulphide isomerase family member
chr14_+_55661272 0.03 ENST00000555573.5
kinectin 1
chr4_-_142560669 0.03 ENST00000510812.5
inositol polyphosphate-4-phosphatase type II B
chr7_-_93226449 0.03 ENST00000394468.7
ENST00000453812.2
HEPACAM family member 2
chr2_+_113072318 0.03 ENST00000393197.3
interleukin 1 family member 10
chrY_-_6874027 0.03 ENST00000215479.10
amelogenin Y-linked
chr17_-_3398410 0.03 ENST00000322608.2
olfactory receptor family 1 subfamily E member 1
chr11_+_62123991 0.03 ENST00000533896.5
ENST00000278849.4
ENST00000394818.8
inner centromere protein
chr15_+_88635626 0.03 ENST00000379224.10
interferon stimulated exonuclease gene 20
chr15_+_66293217 0.03 ENST00000319194.9
ENST00000525134.6
DIS3 like exosome 3'-5' exoribonuclease
chr3_+_171843337 0.02 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
transmembrane protein 212
chr11_+_60280577 0.02 ENST00000679988.1
membrane spanning 4-domains A4A
chr14_+_21918161 0.02 ENST00000390439.2
T cell receptor alpha variable 13-2
chr15_+_66293541 0.02 ENST00000319212.9
ENST00000525109.1
DIS3 like exosome 3'-5' exoribonuclease
chr3_-_169147734 0.02 ENST00000464456.5
MDS1 and EVI1 complex locus
chr1_-_115841116 0.02 ENST00000320238.3
nescient helix-loop-helix 2
chr12_+_5432101 0.02 ENST00000423158.4
neurotrophin 3
chr2_+_159733958 0.02 ENST00000409591.5
membrane associated ring-CH-type finger 7
chr14_-_106154113 0.02 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr4_-_152382522 0.02 ENST00000296555.11
F-box and WD repeat domain containing 7
chr8_-_17697654 0.02 ENST00000297488.10
microtubule associated scaffold protein 1
chr3_-_139480723 0.01 ENST00000511956.1
ENST00000506825.1
retinol binding protein 2
chr12_+_32502114 0.01 ENST00000682739.1
ENST00000427716.7
ENST00000583694.2
FYVE, RhoGEF and PH domain containing 4
chr14_-_21269392 0.01 ENST00000554891.5
ENST00000555883.5
ENST00000553753.5
ENST00000555914.5
ENST00000557336.1
ENST00000555215.5
ENST00000556628.5
ENST00000555137.5
ENST00000556226.5
ENST00000555309.5
ENST00000556142.5
ENST00000554969.5
ENST00000554455.5
ENST00000556513.5
ENST00000557201.5
ENST00000420743.6
ENST00000557768.1
ENST00000553300.6
ENST00000554383.5
ENST00000554539.5
heterogeneous nuclear ribonucleoprotein C
chr9_-_27573653 0.01 ENST00000379995.1
ENST00000647196.1
ENST00000619707.5
ENST00000379997.7
C9orf72-SMCR8 complex subunit
chr18_-_36798482 0.01 ENST00000590258.2
tubulin polyglutamylase complex subunit 2
chr2_-_39121000 0.01 ENST00000402219.8
SOS Ras/Rac guanine nucleotide exchange factor 1
chr10_+_116591010 0.01 ENST00000530319.5
ENST00000527980.5
ENST00000471549.5
ENST00000534537.5
pancreatic lipase related protein 1
chr19_+_50188180 0.01 ENST00000598205.5
myosin heavy chain 14
chr6_+_116369837 0.01 ENST00000645988.1
dermatan sulfate epimerase
chr10_+_116590956 0.01 ENST00000358834.9
ENST00000528052.5
pancreatic lipase related protein 1
chr6_-_49866453 0.01 ENST00000507853.5
cysteine rich secretory protein 1
chr6_-_49866527 0.01 ENST00000335847.9
cysteine rich secretory protein 1
chr7_+_90383672 0.01 ENST00000416322.5
claudin 12
chr8_+_67064316 0.01 ENST00000675306.2
ENST00000678017.1
ENST00000262210.11
ENST00000675869.1
ENST00000677009.1
ENST00000676847.1
ENST00000676471.1
ENST00000678542.1
ENST00000677619.1
ENST00000676605.1
ENST00000678553.1
ENST00000674993.1
ENST00000678318.1
ENST00000676573.1
ENST00000676317.1
ENST00000677592.1
ENST00000679226.1
ENST00000675955.1
ENST00000676882.1
ENST00000678616.1
ENST00000678645.1
ENST00000678747.1
centrosome and spindle pole associated protein 1
chr11_+_60280531 0.01 ENST00000532114.6
membrane spanning 4-domains A4A
chr6_-_52840843 0.01 ENST00000370989.6
glutathione S-transferase alpha 5
chr20_+_10218808 0.01 ENST00000254976.7
ENST00000304886.6
synaptosome associated protein 25
chr2_+_225399684 0.01 ENST00000636099.1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr3_+_111911604 0.01 ENST00000495180.1
pleckstrin homology like domain family B member 2
chr6_+_149566356 0.00 ENST00000367419.10
glycoprotein integral membrane 1
chr1_+_67207614 0.00 ENST00000425614.3
interleukin 23 receptor
chr7_-_80512041 0.00 ENST00000398291.4
G protein subunit alpha transducin 3
chr15_-_51338575 0.00 ENST00000557858.5
ENST00000558328.5
ENST00000396402.6
ENST00000396404.8
ENST00000561075.5
ENST00000405011.6
ENST00000559980.5
ENST00000453807.6
cytochrome P450 family 19 subfamily A member 1
chr1_+_52842753 0.00 ENST00000371528.2
zyg-11 family member A, cell cycle regulator
chr10_+_84424919 0.00 ENST00000543283.2
ENST00000494586.5
coiled-coil serine rich protein 2
chr20_+_45361936 0.00 ENST00000372727.5
ENST00000414310.5
SYS1 golgi trafficking protein
chr12_-_31792290 0.00 ENST00000340398.5
H3.5 histone
chr12_-_123633604 0.00 ENST00000534960.5
ENST00000424014.7
eukaryotic translation initiation factor 2B subunit alpha
chr20_+_45702030 0.00 ENST00000305479.3
WAP four-disulfide core domain 13
chrX_-_15315615 0.00 ENST00000380470.7
ENST00000480796.6
ankyrin repeat and SOCS box containing 11

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX6_IRX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)