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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ISL1

Z-value: 0.57

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Transcription factors associated with ISL1

Gene Symbol Gene ID Gene Info
ENSG00000016082.15 ISL LIM homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ISL1hg38_v1_chr5_+_51383394_513834540.363.8e-01Click!

Activity profile of ISL1 motif

Sorted Z-values of ISL1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91180365 0.59 ENST00000547937.5
decorin
chr2_-_174846405 0.50 ENST00000409597.5
ENST00000413882.6
chimerin 1
chr10_-_77638369 0.36 ENST00000372443.6
potassium calcium-activated channel subfamily M alpha 1
chr3_-_100993409 0.35 ENST00000471714.6
ABI family member 3 binding protein
chr3_-_100993507 0.35 ENST00000284322.10
ABI family member 3 binding protein
chr5_+_32710630 0.34 ENST00000326958.5
natriuretic peptide receptor 3
chr11_-_70717994 0.33 ENST00000659264.1
SH3 and multiple ankyrin repeat domains 2
chr2_-_201698628 0.30 ENST00000602867.1
ENST00000409474.8
membrane palmitoylated protein 4
chr5_+_32711313 0.30 ENST00000265074.13
natriuretic peptide receptor 3
chr19_-_49640092 0.27 ENST00000246792.4
RAS related
chr2_-_189179754 0.26 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr14_-_59870752 0.26 ENST00000611068.1
ENST00000267484.10
reticulon 1
chr6_-_129710145 0.25 ENST00000368149.3
Rho GTPase activating protein 18
chr2_-_157444044 0.24 ENST00000264192.8
cytohesin 1 interacting protein
chr10_-_77637721 0.24 ENST00000638848.1
ENST00000639406.1
ENST00000618048.2
ENST00000639120.1
ENST00000640834.1
ENST00000639601.1
ENST00000638514.1
ENST00000457953.6
ENST00000639090.1
ENST00000639489.1
ENST00000372440.6
ENST00000404771.8
ENST00000638203.1
ENST00000638306.1
ENST00000638351.1
ENST00000638606.1
ENST00000639591.1
ENST00000640182.1
ENST00000640605.1
ENST00000640141.1
potassium calcium-activated channel subfamily M alpha 1
chr17_+_68525795 0.23 ENST00000592800.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chrX_+_136169891 0.23 ENST00000449474.5
four and a half LIM domains 1
chr3_-_15797930 0.22 ENST00000683139.1
ankyrin repeat domain 28
chr9_-_92404559 0.22 ENST00000262551.8
ENST00000375561.10
osteoglycin
chr10_-_77637902 0.22 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
potassium calcium-activated channel subfamily M alpha 1
chrX_+_136169833 0.22 ENST00000628032.2
four and a half LIM domains 1
chr4_+_113049479 0.22 ENST00000671727.1
ENST00000671762.1
ENST00000672366.1
ENST00000672502.1
ENST00000672045.1
ENST00000672251.1
ENST00000672854.1
ankyrin 2
chr1_-_79006773 0.20 ENST00000671209.1
adhesion G protein-coupled receptor L4
chr10_-_77637789 0.20 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
potassium calcium-activated channel subfamily M alpha 1
chr2_-_201698692 0.20 ENST00000315506.11
ENST00000359962.9
ENST00000620095.4
membrane palmitoylated protein 4
chr5_+_137867868 0.20 ENST00000515645.1
myotilin
chr14_+_21990357 0.20 ENST00000390444.1
T cell receptor alpha variable 16
chr2_-_213151590 0.20 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chrX_+_136169664 0.19 ENST00000456445.5
four and a half LIM domains 1
chr1_-_79006680 0.19 ENST00000370742.4
ENST00000656841.1
adhesion G protein-coupled receptor L4
chr12_+_119668109 0.19 ENST00000229328.10
ENST00000630317.1
protein kinase AMP-activated non-catalytic subunit beta 1
chr1_+_196652022 0.19 ENST00000367429.9
ENST00000630130.2
ENST00000359637.2
complement factor H
chr4_+_113049616 0.18 ENST00000504454.5
ENST00000357077.9
ENST00000394537.7
ENST00000672779.1
ENST00000264366.10
ankyrin 2
chr12_-_49897056 0.18 ENST00000552863.5
Fas apoptotic inhibitory molecule 2
chr2_-_174847015 0.18 ENST00000650938.1
chimerin 1
chr6_+_31739948 0.18 ENST00000375755.8
ENST00000425703.5
ENST00000375750.9
ENST00000375703.7
ENST00000375740.7
mutS homolog 5
chr9_-_110999458 0.17 ENST00000374430.6
lysophosphatidic acid receptor 1
chr1_-_107688492 0.16 ENST00000415432.6
vav guanine nucleotide exchange factor 3
chr1_-_94925759 0.16 ENST00000415017.1
ENST00000545882.5
calponin 3
chr13_-_70108441 0.16 ENST00000377844.9
ENST00000545028.2
kelch like family member 1
chr4_-_185956652 0.16 ENST00000355634.9
sorbin and SH3 domain containing 2
chr7_-_13986498 0.15 ENST00000420159.6
ENST00000399357.7
ENST00000403527.5
ETS variant transcription factor 1
chrX_+_136169624 0.15 ENST00000394153.6
four and a half LIM domains 1
chr7_-_13986439 0.15 ENST00000443608.5
ENST00000438956.5
ETS variant transcription factor 1
chr6_+_31655888 0.15 ENST00000375916.4
apolipoprotein M
chr6_+_144583198 0.14 ENST00000367526.8
utrophin
chr12_+_78863962 0.14 ENST00000393240.7
synaptotagmin 1
chr1_+_156054761 0.13 ENST00000368305.9
ENST00000368304.9
ENST00000368302.3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr10_-_27240505 0.13 ENST00000375888.5
ENST00000676732.1
acyl-CoA binding domain containing 5
chr1_+_222928415 0.13 ENST00000284476.7
dispatched RND transporter family member 1
chr6_+_167291329 0.13 ENST00000366829.2
unc-93 homolog A
chr12_+_94148553 0.13 ENST00000258526.9
plexin C1
chr6_+_36029082 0.13 ENST00000472333.1
mitogen-activated protein kinase 14
chr4_+_73481737 0.12 ENST00000226355.5
afamin
chrX_+_136197039 0.12 ENST00000370683.6
four and a half LIM domains 1
chr5_+_137867852 0.11 ENST00000421631.6
ENST00000239926.9
myotilin
chr2_+_241350087 0.11 ENST00000451310.1
septin 2
chr7_+_130293134 0.11 ENST00000445470.6
ENST00000492072.5
ENST00000222482.10
ENST00000473956.5
ENST00000493259.5
ENST00000486598.1
carboxypeptidase A4
chr22_-_32255344 0.11 ENST00000266086.6
solute carrier family 5 member 4
chr5_+_134846065 0.11 ENST00000504727.1
ENST00000435259.2
ENST00000508791.1
chromosome 5 open reading frame 24
chr6_+_167291309 0.11 ENST00000230256.8
unc-93 homolog A
chr5_+_141370236 0.11 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr1_+_1001002 0.10 ENST00000624697.4
ENST00000624652.1
ISG15 ubiquitin like modifier
chr3_-_138594129 0.10 ENST00000485115.1
ENST00000484888.5
ENST00000468900.5
ENST00000481834.5
ENST00000264982.8
centrosomal protein 70
chr4_+_61201223 0.10 ENST00000512091.6
adhesion G protein-coupled receptor L3
chr10_+_17228215 0.10 ENST00000544301.7
vimentin
chr2_-_223602284 0.10 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr9_+_37667997 0.10 ENST00000539465.5
FERM and PDZ domain containing 1
chr14_-_100569780 0.10 ENST00000355173.7
brain enriched guanylate kinase associated
chr7_+_90709530 0.10 ENST00000406263.5
cyclin dependent kinase 14
chr2_-_74421560 0.10 ENST00000612891.4
ENST00000640331.1
ENST00000684111.1
chromosome 2 open reading frame 81
chr8_+_26390362 0.10 ENST00000518611.5
BCL2 interacting protein 3 like
chr1_+_197413827 0.10 ENST00000367397.1
ENST00000681519.1
crumbs cell polarity complex component 1
chr5_+_136132772 0.10 ENST00000545279.6
ENST00000507118.5
ENST00000511116.5
ENST00000545620.5
ENST00000509297.6
SMAD family member 5
chr4_-_185956348 0.10 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
sorbin and SH3 domain containing 2
chr12_+_54008961 0.10 ENST00000040584.6
homeobox C8
chr6_-_110815152 0.09 ENST00000413605.6
cyclin dependent kinase 19
chr2_+_28395511 0.09 ENST00000436647.1
FOS like 2, AP-1 transcription factor subunit
chr1_-_120176450 0.09 ENST00000578049.4
SEC22 homolog B, vesicle trafficking protein
chr8_-_100309368 0.09 ENST00000523167.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr8_-_19682576 0.09 ENST00000332246.10
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr7_+_90709231 0.09 ENST00000446790.5
ENST00000265741.7
cyclin dependent kinase 14
chr8_+_35235467 0.09 ENST00000404895.7
unc-5 netrin receptor D
chr13_+_45702306 0.09 ENST00000533564.1
ENST00000310521.6
chibby family member 2
chrX_-_72307148 0.09 ENST00000453707.6
ENST00000373619.7
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chrX_+_55452119 0.08 ENST00000342972.3
MAGE family member H1
chr6_+_63521738 0.08 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chr17_-_55511434 0.08 ENST00000636752.1
small integral membrane protein 36
chr8_-_12194067 0.08 ENST00000524571.6
ENST00000533852.6
ENST00000533513.1
ENST00000448228.6
ENST00000534520.5
family with sequence similarity 86 member B1
chr15_-_55270383 0.08 ENST00000396307.6
RAB27A, member RAS oncogene family
chr1_+_103617427 0.08 ENST00000423678.2
ENST00000414303.7
amylase alpha 2A
chr17_+_7015035 0.08 ENST00000552775.1
chromosome 17 open reading frame 49
chr3_-_185821092 0.08 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chr20_-_50115935 0.08 ENST00000340309.7
ENST00000415862.6
ENST00000371677.7
ubiquitin conjugating enzyme E2 V1
chr14_-_106557465 0.08 ENST00000390625.3
immunoglobulin heavy variable 3-49
chr6_-_110815408 0.08 ENST00000368911.8
cyclin dependent kinase 19
chr8_+_69492793 0.08 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
sulfatase 1
chr16_-_30787169 0.08 ENST00000262525.6
zinc finger protein 629
chrX_-_72306962 0.08 ENST00000246139.9
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr13_+_45702411 0.08 ENST00000610924.1
chibby family member 2
chrX_+_51893533 0.08 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGE family member D1
chr8_-_130386864 0.08 ENST00000521426.5
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr17_-_21253398 0.08 ENST00000611551.1
N-acetyltransferase domain containing 1
chr20_+_38962299 0.08 ENST00000373325.6
ENST00000373323.8
ENST00000252011.8
ENST00000615559.1
DEAH-box helicase 35
novel transcript, sense intronic to DHX35
chr12_-_42237727 0.08 ENST00000548917.1
YY1 associated factor 2
chr4_+_168497066 0.08 ENST00000261509.10
palladin, cytoskeletal associated protein
chr16_+_33009175 0.08 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr2_+_157257687 0.08 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr4_+_168497044 0.07 ENST00000505667.6
palladin, cytoskeletal associated protein
chr14_-_106269133 0.07 ENST00000390609.3
immunoglobulin heavy variable 3-23
chr12_+_78864768 0.07 ENST00000261205.9
ENST00000457153.6
synaptotagmin 1
chr2_+_167135901 0.07 ENST00000628543.2
xin actin binding repeat containing 2
chr14_-_77028663 0.07 ENST00000238647.5
interferon regulatory factor 2 binding protein like
chr14_-_106675544 0.07 ENST00000390632.2
immunoglobulin heavy variable 3-66
chr10_-_113854069 0.07 ENST00000361384.7
DNA cross-link repair 1A
chr17_+_35587239 0.06 ENST00000621914.4
ENST00000621668.4
ENST00000616681.4
ENST00000612035.4
ENST00000610402.5
ENST00000614600.4
ENST00000590432.5
ENST00000612116.5
adaptor related protein complex 2 subunit beta 1
chr2_+_233307806 0.06 ENST00000447536.5
ENST00000409110.6
S-antigen visual arrestin
chr18_-_24397784 0.06 ENST00000399441.4
ENST00000319481.8
oxysterol binding protein like 1A
chr4_+_70195719 0.06 ENST00000683306.1
odontogenic, ameloblast associated
chr1_-_156248013 0.06 ENST00000368270.2
progestin and adipoQ receptor family member 6
chr14_-_106538331 0.06 ENST00000390624.3
immunoglobulin heavy variable 3-48
chr5_-_138875290 0.06 ENST00000521094.2
ENST00000274711.7
leucine rich repeat transmembrane neuronal 2
chrX_+_21940693 0.06 ENST00000404933.7
ENST00000379404.5
spermine synthase
chr19_-_18606779 0.06 ENST00000684169.1
ENST00000392386.8
cytokine receptor like factor 1
chr5_+_43602648 0.06 ENST00000505678.6
ENST00000512422.5
ENST00000264663.9
ENST00000670904.1
ENST00000653251.1
nicotinamide nucleotide transhydrogenase
chr5_+_103120149 0.06 ENST00000515845.5
ENST00000321521.13
ENST00000507921.5
diphosphoinositol pentakisphosphate kinase 2
chr17_-_59151794 0.06 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr1_-_156248084 0.06 ENST00000652405.1
ENST00000335852.6
ENST00000540423.5
ENST00000612424.4
ENST00000613336.4
ENST00000623241.3
progestin and adipoQ receptor family member 6
chr19_-_50163146 0.05 ENST00000600293.5
IZUMO family member 2
chr6_+_31547560 0.05 ENST00000376148.9
ENST00000376145.8
NFKB inhibitor like 1
chr10_+_49610297 0.05 ENST00000374115.5
solute carrier family 18 member A3
chr1_-_156248038 0.05 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
progestin and adipoQ receptor family member 6
chr12_-_10098940 0.05 ENST00000420265.2
C-type lectin domain family 1 member A
chr6_+_168017873 0.05 ENST00000351261.4
ENST00000354419.6
kinesin family member 25
chr19_-_50163175 0.05 ENST00000293405.7
IZUMO family member 2
chr12_-_10098977 0.05 ENST00000315330.8
ENST00000457018.6
C-type lectin domain family 1 member A
chr1_+_103750406 0.05 ENST00000370079.3
amylase alpha 1C
chr8_+_38728186 0.05 ENST00000519416.5
ENST00000520615.5
transforming acidic coiled-coil containing protein 1
chr5_+_53560627 0.05 ENST00000296684.10
ENST00000506765.1
NADH:ubiquinone oxidoreductase subunit S4
chr5_+_140700437 0.05 ENST00000274712.8
zinc finger matrin-type 2
chr6_-_111483700 0.05 ENST00000435970.5
ENST00000358835.7
REV3 like, DNA directed polymerase zeta catalytic subunit
chr16_+_2148603 0.05 ENST00000210187.11
RAB26, member RAS oncogene family
chr12_-_102197827 0.05 ENST00000329406.5
pro-melanin concentrating hormone
chr8_+_109086585 0.05 ENST00000518632.2
thyrotropin releasing hormone receptor
chr2_+_218607914 0.05 ENST00000417849.5
phospholipase C delta 4
chr1_-_160285120 0.05 ENST00000368072.10
peroxisomal biogenesis factor 19
chr13_+_77741160 0.05 ENST00000314070.9
ENST00000351546.7
SLAIN motif family member 1
chr17_+_39667964 0.05 ENST00000394246.1
phenylethanolamine N-methyltransferase
chr6_+_27388748 0.04 ENST00000244576.9
zinc finger protein 391
chr9_-_131709721 0.04 ENST00000372190.7
Rap guanine nucleotide exchange factor 1
chr1_-_159714581 0.04 ENST00000255030.9
ENST00000437342.1
ENST00000368112.5
ENST00000368111.5
ENST00000368110.1
C-reactive protein
chr17_+_37375974 0.04 ENST00000615133.2
ENST00000611038.4
chromosome 17 open reading frame 78
chr12_+_21372899 0.04 ENST00000240652.8
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chr11_+_121102666 0.04 ENST00000264037.2
tectorin alpha
chr3_-_100993448 0.04 ENST00000495063.6
ENST00000486770.7
ENST00000530539.2
ABI family member 3 binding protein
chr3_-_124887353 0.04 ENST00000296181.9
integrin subunit beta 5
chr22_+_29883158 0.04 ENST00000333027.7
ENST00000401950.7
ENST00000445401.5
ENST00000323630.9
ENST00000351488.7
myotubularin related protein 3
chr3_+_148791058 0.04 ENST00000491148.5
carboxypeptidase B1
chr18_+_48539017 0.04 ENST00000256413.8
cap binding complex dependent translation initiation factor
chr19_-_17377334 0.04 ENST00000252590.9
ENST00000599426.1
plasmalemma vesicle associated protein
chr2_+_176157293 0.04 ENST00000683222.1
homeobox D3
chr7_-_78489900 0.04 ENST00000636039.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_+_119782094 0.04 ENST00000393716.8
nuclear receptor subfamily 1 group I member 2
chr3_+_159069252 0.04 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1 readthrough
chr11_-_6030758 0.04 ENST00000641900.1
olfactory receptor family 56 subfamily A member 1
chr14_-_106411021 0.03 ENST00000390618.2
immunoglobulin heavy variable 3-38 (non-functional)
chr16_+_20763990 0.03 ENST00000289416.10
acyl-CoA synthetase medium chain family member 3
chr10_+_112950586 0.03 ENST00000355717.9
ENST00000352065.10
ENST00000369395.6
ENST00000545257.6
transcription factor 7 like 2
chr17_-_42979993 0.03 ENST00000409103.5
ENST00000360221.8
ENST00000454303.1
ENST00000591916.7
ENST00000451885.3
PTGES3L-AARSD1 readthrough
prostaglandin E synthase 3 like
chrX_-_103686687 0.03 ENST00000441076.7
ENST00000422355.5
ENST00000442614.5
ENST00000451301.5
mortality factor 4 like 2
chr18_+_616711 0.03 ENST00000579494.1
clusterin like 1
chrY_-_6872608 0.03 ENST00000383036.1
amelogenin Y-linked
chr3_-_157503375 0.03 ENST00000362010.7
ventricular zone expressed PH domain containing 1
chr12_+_92702843 0.03 ENST00000397833.3
pleckstrin homology and RhoGEF domain containing G7
chr12_+_80716906 0.03 ENST00000228644.4
myogenic factor 5
chr17_+_44957907 0.03 ENST00000678938.1
N-myristoyltransferase 1
chr3_-_157503574 0.03 ENST00000494677.5
ENST00000468233.5
ventricular zone expressed PH domain containing 1
chr8_-_78805306 0.03 ENST00000639719.1
ENST00000263851.9
interleukin 7
chr8_-_78805515 0.03 ENST00000379113.6
ENST00000541183.2
interleukin 7
chr3_-_157503339 0.03 ENST00000392833.6
ventricular zone expressed PH domain containing 1
chr22_-_42959852 0.03 ENST00000402229.5
ENST00000407585.5
ENST00000453079.1
protein kinase C and casein kinase substrate in neurons 2
chr14_+_61697622 0.03 ENST00000539097.2
hypoxia inducible factor 1 subunit alpha
chr16_+_55656249 0.03 ENST00000219833.13
ENST00000574918.2
solute carrier family 6 member 2
chr3_-_49029378 0.03 ENST00000442157.2
ENST00000326739.9
ENST00000677010.1
ENST00000678724.1
ENST00000429182.6
inosine monophosphate dehydrogenase 2
chr12_-_56643499 0.02 ENST00000551570.5
ATP synthase F1 subunit beta
chr4_-_99894368 0.02 ENST00000226522.8
ENST00000499666.7
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr17_-_42577663 0.02 ENST00000590760.5
ENST00000587209.5
ENST00000393795.8
ENST00000253789.9
PSMC3 interacting protein
chr1_-_92792396 0.02 ENST00000370331.5
ENST00000540033.2
ecotropic viral integration site 5
chr1_+_15659869 0.02 ENST00000345034.1
regulator of solute carriers 1
chr2_+_202073282 0.02 ENST00000459709.5
KIAA2012
chr18_-_5544250 0.02 ENST00000540638.6
ENST00000342933.7
erythrocyte membrane protein band 4.1 like 3
chr3_+_57890011 0.02 ENST00000494088.6
ENST00000438794.5
sarcolemma associated protein
chr11_-_63015804 0.02 ENST00000535878.5
ENST00000545207.5
solute carrier family 22 member 8
chr18_+_616672 0.02 ENST00000338387.11
clusterin like 1
chr2_+_202073249 0.02 ENST00000498697.3
KIAA2012
chr12_+_92702983 0.02 ENST00000344636.6
ENST00000544406.2
pleckstrin homology and RhoGEF domain containing G7
chr5_+_175861628 0.02 ENST00000509837.5
complexin 2
chr3_+_38265802 0.02 ENST00000311856.9
solute carrier family 22 member 13
chr9_+_128322540 0.02 ENST00000609948.1
ENST00000608951.5
coenzyme Q4
chr8_-_100559702 0.02 ENST00000520311.5
ENST00000520552.5
ENST00000521345.1
ENST00000523000.5
ENST00000335659.7
ENST00000358990.3
ENST00000519597.5
ankyrin repeat domain 46

Network of associatons between targets according to the STRING database.

First level regulatory network of ISL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 1.0 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0007225 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.0 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.6 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.1 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.0 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.0 0.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.0 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 1.0 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0005334 norepinephrine:sodium symporter activity(GO:0005334)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.0 GO:0033265 choline binding(GO:0033265)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate