Project

avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

Navigation
Downloads

Results for ISL2

Z-value: 0.27

Motif logo

Transcription factors associated with ISL2

Gene Symbol Gene ID Gene Info
ENSG00000159556.10 ISL LIM homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ISL2hg38_v1_chr15_+_76336755_763367790.019.9e-01Click!

Activity profile of ISL2 motif

Sorted Z-values of ISL2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_155455830 0.14 ENST00000159060.3
NADPH oxidase 3
chr1_+_14929734 0.11 ENST00000376028.8
ENST00000400798.6
kazrin, periplakin interacting protein
chr5_+_140875299 0.11 ENST00000613593.1
ENST00000398631.3
protocadherin alpha 12
chr8_-_124565699 0.10 ENST00000519168.5
MTSS I-BAR domain containing 1
chr7_-_111392915 0.10 ENST00000450877.5
inner mitochondrial membrane peptidase subunit 2
chr2_-_84881238 0.09 ENST00000335459.9
TraB domain containing 2A
chr4_-_89835617 0.08 ENST00000611107.1
ENST00000345009.8
ENST00000505199.5
ENST00000502987.5
synuclein alpha
chr17_-_8119047 0.08 ENST00000318227.4
arachidonate lipoxygenase 3
chr9_+_12693327 0.08 ENST00000388918.10
tyrosinase related protein 1
chr3_-_142029108 0.08 ENST00000497579.5
transcription factor Dp-2
chr12_-_95116967 0.08 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chrX_-_32155462 0.07 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chrX_-_31266925 0.07 ENST00000680557.1
ENST00000378680.6
ENST00000378723.7
ENST00000680768.2
ENST00000681870.1
ENST00000680355.1
ENST00000682322.1
ENST00000682600.1
ENST00000680162.2
ENST00000681153.1
ENST00000681334.1
dystrophin
chr20_-_52105644 0.07 ENST00000371523.8
ZFP64 zinc finger protein
chr15_-_82709886 0.07 ENST00000666055.1
ENST00000261722.8
ENST00000535513.2
adaptor related protein complex 3 subunit beta 2
chr9_+_72577939 0.07 ENST00000645773.1
transmembrane channel like 1
chr5_-_140346596 0.07 ENST00000230990.7
heparin binding EGF like growth factor
chr2_-_162152404 0.07 ENST00000375497.3
glucagon
chr11_-_124320197 0.06 ENST00000624618.2
olfactory receptor family 8 subfamily D member 2
chrX_-_85379659 0.06 ENST00000262753.9
POF1B actin binding protein
chr4_+_127781815 0.06 ENST00000508776.5
heat shock protein family A (Hsp70) member 4 like
chrX_-_31266857 0.05 ENST00000378702.8
ENST00000361471.8
dystrophin
chr7_+_123601815 0.05 ENST00000451215.6
ankyrin repeat and SOCS box containing 15
chr6_+_31137646 0.05 ENST00000547221.1
psoriasis susceptibility 1 candidate 1
chr7_+_123601836 0.05 ENST00000434204.5
ankyrin repeat and SOCS box containing 15
chr18_-_55423757 0.05 ENST00000675707.1
transcription factor 4
chr7_-_16804987 0.04 ENST00000401412.5
ENST00000419304.7
anterior gradient 2, protein disulphide isomerase family member
chrX_+_135309480 0.04 ENST00000635820.1
embryonic testis differentiation homolog C
chr18_-_55635948 0.04 ENST00000565124.4
ENST00000398339.5
transcription factor 4
chr10_-_5003850 0.04 ENST00000421196.7
ENST00000455190.2
ENST00000380753.8
aldo-keto reductase family 1 member C2
chr4_+_15469865 0.04 ENST00000515124.6
ENST00000512702.6
ENST00000503292.6
ENST00000424120.6
ENST00000507954.5
ENST00000514450.3
ENST00000503658.2
coiled-coil and C2 domain containing 2A
chr1_-_247760556 0.04 ENST00000641256.1
olfactory receptor family 1 subfamily C member 1
chr18_-_3845292 0.04 ENST00000400145.6
DLG associated protein 1
chrY_+_18546691 0.04 ENST00000309834.8
ENST00000307393.3
ENST00000382856.2
heat shock transcription factor Y-linked 1
chr6_+_130018565 0.04 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr11_-_13496018 0.04 ENST00000529816.1
parathyroid hormone
chr13_-_46142834 0.04 ENST00000674665.1
lymphocyte cytosolic protein 1
chr6_+_26402237 0.04 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
butyrophilin subfamily 3 member A1
chr7_-_24757926 0.04 ENST00000342947.9
ENST00000419307.6
gasdermin E
chr9_-_92404559 0.04 ENST00000262551.8
ENST00000375561.10
osteoglycin
chr11_+_5389377 0.04 ENST00000328611.5
olfactory receptor family 51 subfamily M member 1
chr14_-_67412112 0.04 ENST00000216446.9
pleckstrin 2
chr7_-_45111673 0.04 ENST00000461363.1
ENST00000258770.8
ENST00000495078.1
ENST00000494076.5
ENST00000478532.5
ENST00000361278.7
transforming growth factor beta regulator 4
chr22_-_28711931 0.04 ENST00000434810.5
ENST00000456369.5
checkpoint kinase 2
chr19_-_3557563 0.04 ENST00000389395.7
ENST00000355415.7
major facilitator superfamily domain containing 12
chr17_-_50707855 0.03 ENST00000285243.7
ankyrin repeat domain 40
chr11_-_13495984 0.03 ENST00000282091.6
parathyroid hormone
chr5_+_40841308 0.03 ENST00000381677.4
ENST00000254691.10
caspase recruitment domain family member 6
chr6_-_24358036 0.03 ENST00000378454.8
doublecortin domain containing 2
chr2_+_167135901 0.03 ENST00000628543.2
xin actin binding repeat containing 2
chr19_-_45730861 0.03 ENST00000317683.4
F-box protein 46
chrX_-_85379703 0.03 ENST00000373145.3
POF1B actin binding protein
chrY_-_23694579 0.03 ENST00000343584.10
PTPN13 like Y-linked pseudogene 3
chrX_-_15314543 0.03 ENST00000344384.8
ankyrin repeat and SOCS box containing 11
chr21_+_38272410 0.03 ENST00000398934.5
ENST00000398930.5
potassium inwardly rectifying channel subfamily J member 15
chr8_+_106726115 0.03 ENST00000521592.5
oxidation resistance 1
chr14_+_22202561 0.03 ENST00000390460.1
T cell receptor alpha variable 26-2
chr17_-_66229380 0.03 ENST00000205948.11
apolipoprotein H
chr5_+_40909490 0.03 ENST00000313164.10
complement C7
chr18_+_63907948 0.03 ENST00000238508.8
serpin family B member 10
chrX_+_66164340 0.03 ENST00000441993.7
ENST00000419594.6
ENST00000425114.2
hephaestin
chr12_+_69825221 0.03 ENST00000552032.7
myelin regulatory factor like
chr2_+_233760265 0.03 ENST00000305208.10
ENST00000360418.4
UDP glucuronosyltransferase family 1 member A1
chr17_-_10469558 0.02 ENST00000255381.2
myosin heavy chain 4
chr14_+_92323154 0.02 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
solute carrier family 24 member 4
chr4_-_119322128 0.02 ENST00000274024.4
fatty acid binding protein 2
chr12_+_69825273 0.02 ENST00000547771.6
myelin regulatory factor like
chr10_+_61662921 0.02 ENST00000648843.3
ENST00000330194.2
ENST00000389639.3
ciliary associated calcium binding coiled-coil 1
chr3_+_134795248 0.02 ENST00000398015.8
EPH receptor B1
chr3_-_20186127 0.02 ENST00000425061.5
ENST00000443724.5
ENST00000421451.5
ENST00000452020.5
ENST00000417364.1
ENST00000306698.6
ENST00000419233.6
ENST00000263753.8
ENST00000437051.5
ENST00000442720.5
ENST00000412997.6
shugoshin 1
chr2_+_32277883 0.02 ENST00000238831.9
Yip1 domain family member 4
chr11_+_86374736 0.02 ENST00000354755.5
ENST00000531271.5
ENST00000445632.7
coiled-coil domain containing 81
chr19_+_3185911 0.02 ENST00000246117.9
ENST00000588428.5
nicalin
chr17_-_5035418 0.02 ENST00000254853.10
ENST00000424747.1
solute carrier family 52 member 1
chr12_-_118190510 0.02 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAO kinase 3
chr7_+_16661182 0.02 ENST00000446596.5
ENST00000452975.6
ENST00000438834.5
basic leucine zipper and W2 domains 2
chr9_+_35042213 0.02 ENST00000378745.3
ENST00000312292.6
chromosome 9 open reading frame 131
chr1_+_62597510 0.02 ENST00000371129.4
angiopoietin like 3
chr1_+_149899618 0.02 ENST00000369150.1
bolA family member 1
chr9_-_21368962 0.02 ENST00000610660.1
interferon alpha 13
chr2_-_199955464 0.02 ENST00000354611.9
tRNA-yW synthesizing protein 5
chrX_-_72808210 0.02 ENST00000419795.6
ENST00000458170.1
family with sequence similarity 236 member D
chr11_+_28108248 0.02 ENST00000406787.7
ENST00000403099.5
ENST00000407364.8
methyltransferase like 15
chr2_+_113067970 0.02 ENST00000341010.6
interleukin 1 family member 10
chr1_-_178871060 0.02 ENST00000234816.7
angiopoietin like 1
chr19_+_4402615 0.02 ENST00000301280.10
chromatin assembly factor 1 subunit A
chr11_-_107858777 0.01 ENST00000525815.6
solute carrier family 35 member F2
chr14_+_101809795 0.01 ENST00000350249.7
ENST00000557621.5
ENST00000556946.1
protein phosphatase 2 regulatory subunit B'gamma
chr18_-_3845321 0.01 ENST00000539435.5
ENST00000400147.6
DLG associated protein 1
chr1_+_15341744 0.01 ENST00000444385.5
forkhead associated phosphopeptide binding domain 1
chr12_+_1970809 0.01 ENST00000683781.1
ENST00000682462.1
calcium voltage-gated channel subunit alpha1 C
chr12_+_1970772 0.01 ENST00000682544.1
calcium voltage-gated channel subunit alpha1 C
chr3_-_191282383 0.01 ENST00000427544.6
urotensin 2B
chr17_+_10697576 0.01 ENST00000379774.5
ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
chr1_-_178871022 0.01 ENST00000367629.1
angiopoietin like 1
chr3_+_134795277 0.01 ENST00000647596.1
EPH receptor B1
chr11_+_102112445 0.01 ENST00000524575.5
Yes1 associated transcriptional regulator
chr15_+_48191648 0.01 ENST00000646012.1
ENST00000561127.5
ENST00000647546.1
ENST00000559641.5
ENST00000417307.3
solute carrier family 12 member 1
cortexin 2
chr2_-_208146150 0.01 ENST00000260988.5
crystallin gamma B
chrX_-_21658324 0.01 ENST00000379499.3
kelch like family member 34
chr12_-_51028234 0.01 ENST00000547688.7
ENST00000394904.9
solute carrier family 11 member 2
chr3_+_42979281 0.01 ENST00000488863.5
ENST00000430121.3
golgi associated kinase 1A
chr2_-_169031317 0.01 ENST00000650372.1
ATP binding cassette subfamily B member 11
chr1_-_223665685 0.01 ENST00000366872.10
calpain 8
chr7_-_108240049 0.01 ENST00000379022.8
neuronal cell adhesion molecule
chr6_+_26402289 0.01 ENST00000414912.2
butyrophilin subfamily 3 member A1
chr17_+_4807119 0.01 ENST00000263088.11
ENST00000572940.5
phospholipase D2
chr6_+_26440472 0.01 ENST00000494393.5
ENST00000482451.5
ENST00000471353.5
ENST00000361232.7
ENST00000487627.5
ENST00000496719.1
ENST00000244519.7
ENST00000490254.5
ENST00000487272.1
butyrophilin subfamily 3 member A3
chr2_+_233671879 0.01 ENST00000354728.5
UDP glucuronosyltransferase family 1 member A9
chr1_-_17439657 0.01 ENST00000375436.9
regulator of chromosome condensation 2
chr11_+_35186820 0.01 ENST00000531110.6
ENST00000525685.6
CD44 molecule (Indian blood group)
chr10_-_126670686 0.01 ENST00000488181.3
chromosome 10 open reading frame 90
chr11_-_28108109 0.01 ENST00000263181.7
kinesin family member 18A
chr1_-_21050952 0.01 ENST00000264211.12
eukaryotic translation initiation factor 4 gamma 3
chr17_+_7252502 0.01 ENST00000570322.5
ENST00000576496.5
ENST00000574841.2
elongator acetyltransferase complex subunit 5
chr1_-_13285154 0.01 ENST00000357367.6
ENST00000614831.1
PRAME family member 8
chr20_-_31390483 0.01 ENST00000376315.2
defensin beta 119
chr1_+_149899561 0.00 ENST00000369152.6
bolA family member 1
chr11_-_35360050 0.00 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
solute carrier family 1 member 2
chr12_-_10130082 0.00 ENST00000533022.5
C-type lectin domain containing 7A
chr4_+_25160631 0.00 ENST00000510415.1
ENST00000507794.2
ENST00000512921.4
SEPSECS antisense RNA 1 (head to head)
phosphatidylinositol 4-kinase type 2 beta
chr7_-_87713287 0.00 ENST00000416177.1
ENST00000265724.8
ENST00000543898.5
ATP binding cassette subfamily B member 1
chr14_-_90331904 0.00 ENST00000628832.1
ENST00000354366.8
NRDE-2, necessary for RNA interference, domain containing
chr5_+_132873660 0.00 ENST00000296877.3
liver enriched antimicrobial peptide 2
chrX_+_11293411 0.00 ENST00000348912.4
ENST00000380714.7
ENST00000380712.7
amelogenin X-linked
chr16_+_28553908 0.00 ENST00000317058.8
SAGA complex associated factor 29
chr17_-_3592877 0.00 ENST00000399756.8
transient receptor potential cation channel subfamily V member 1
chr4_-_103019634 0.00 ENST00000510559.1
ENST00000296422.12
ENST00000394789.7
solute carrier family 9 member B1
chr12_+_4720395 0.00 ENST00000252318.7
polypeptide N-acetylgalactosaminyltransferase 8
chr2_-_158380960 0.00 ENST00000409187.5
coiled-coil domain containing 148
chr17_-_7404039 0.00 ENST00000576017.1
ENST00000302422.4
transmembrane protein 256
chr19_+_48695952 0.00 ENST00000522966.2
ENST00000425340.3
ENST00000391876.5
fucosyltransferase 2
chr2_-_197675578 0.00 ENST00000295049.9
raftlin family member 2
chr2_+_233917371 0.00 ENST00000324695.9
ENST00000433712.6
transient receptor potential cation channel subfamily M member 8
chr7_-_116030750 0.00 ENST00000265440.12
ENST00000320239.11
transcription factor EC
chr12_-_10130241 0.00 ENST00000353231.9
ENST00000525605.1
C-type lectin domain containing 7A
chrX_+_55717796 0.00 ENST00000262850.7
Ras related GTP binding B
chr10_-_49188380 0.00 ENST00000374153.7
ENST00000374148.1
ENST00000374151.7
transmembrane protein 273
chr18_-_36798482 0.00 ENST00000590258.2
tubulin polyglutamylase complex subunit 2
chr3_-_20012250 0.00 ENST00000389050.5
protein phosphatase 2C like domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ISL2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.0 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.0 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)