Project

avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

Navigation
Downloads

Results for KLF3

Z-value: 1.71

Motif logo

logo of

Transcription factors associated with KLF3

Gene Symbol Gene ID Gene Info
KLF3
ENSG00000109787.13 Kruppel like factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF3hg38_v1_chr4_+_38664189_386642060.658.3e-02Click!

Activity profile of KLF3 motif

Sorted Z-values of KLF3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_35501878 2.73 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
DMKN
dermokine
chr15_+_43593054 2.11 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
CKMT1B
creatine kinase, mitochondrial 1B
chr19_-_51020019 1.97 ENST00000309958.7
KLK10
kallikrein related peptidase 10
chr1_+_2073462 1.76 ENST00000400921.6
PRKCZ
protein kinase C zeta
chr18_+_63887698 1.37 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
SERPINB2
serpin family B member 2
chr20_+_46008900 1.32 ENST00000372330.3
MMP9
matrix metallopeptidase 9
chr6_-_106974721 1.32 ENST00000606017.2
ENST00000620405.1
CD24
CD24 molecule
chr1_+_2073986 1.15 ENST00000461106.6
PRKCZ
protein kinase C zeta
chr6_-_136526472 1.12 ENST00000454590.5
ENST00000432797.6
MAP7
microtubule associated protein 7
chr6_-_136525961 1.00 ENST00000438100.6
MAP7
microtubule associated protein 7
chr11_+_59713403 0.99 ENST00000641815.1
STX3
syntaxin 3
chr10_+_46375645 0.98 ENST00000622769.4
ANXA8L1
annexin A8 like 1
chr10_-_47484133 0.97 ENST00000583911.5
ENST00000611843.4
ANXA8
annexin A8
chr10_-_47484081 0.96 ENST00000583448.2
ENST00000583874.5
ENST00000585281.6
ANXA8
annexin A8
chr19_-_51020154 0.96 ENST00000391805.5
ENST00000599077.1
KLK10
kallikrein related peptidase 10
chr1_+_156061142 0.94 ENST00000361084.10
RAB25
RAB25, member RAS oncogene family
chr19_-_51019699 0.94 ENST00000358789.8
KLK10
kallikrein related peptidase 10
chr12_-_8662073 0.89 ENST00000535411.5
ENST00000540087.5
MFAP5
microfibril associated protein 5
chr16_+_67199509 0.88 ENST00000477898.5
ELMO3
engulfment and cell motility 3
chr1_+_43935807 0.85 ENST00000438616.3
ARTN
artemin
chr11_-_5441514 0.81 ENST00000380211.1
OR51I1
olfactory receptor family 51 subfamily I member 1
chr1_-_26960413 0.80 ENST00000320567.6
KDF1
keratinocyte differentiation factor 1
chr7_+_121873152 0.78 ENST00000650826.1
ENST00000650728.1
ENST00000393386.7
ENST00000651390.1
ENST00000651842.1
ENST00000650681.1
PTPRZ1
protein tyrosine phosphatase receptor type Z1
chr19_+_35116262 0.78 ENST00000604255.5
ENST00000344013.10
ENST00000346446.9
ENST00000603449.5
ENST00000605550.5
ENST00000604804.5
ENST00000605552.5
FXYD3
FXYD domain containing ion transport regulator 3
chr1_+_34782259 0.77 ENST00000373362.3
GJB3
gap junction protein beta 3
chr19_+_45340736 0.75 ENST00000391946.7
KLC3
kinesin light chain 3
chr19_+_45340760 0.75 ENST00000585434.5
KLC3
kinesin light chain 3
chr10_+_46375619 0.72 ENST00000584982.7
ENST00000613703.4
ANXA8L1
annexin A8 like 1
chr1_-_26960369 0.70 ENST00000616918.1
KDF1
keratinocyte differentiation factor 1
chr7_+_26152188 0.69 ENST00000056233.4
NFE2L3
nuclear factor, erythroid 2 like 3
chr3_+_50155305 0.68 ENST00000002829.8
ENST00000426511.5
SEMA3F
semaphorin 3F
chr20_+_45174894 0.68 ENST00000243924.4
PI3
peptidase inhibitor 3
chr1_-_183590876 0.67 ENST00000367536.5
NCF2
neutrophil cytosolic factor 2
chr2_+_130836904 0.65 ENST00000409359.7
ARHGEF4
Rho guanine nucleotide exchange factor 4
chr1_-_12616762 0.65 ENST00000464917.5
DHRS3
dehydrogenase/reductase 3
chr12_-_85836372 0.64 ENST00000361228.5
RASSF9
Ras association domain family member 9
chr3_+_111999326 0.63 ENST00000494932.1
TAGLN3
transgelin 3
chr13_+_36431510 0.62 ENST00000630422.2
CCNA1
cyclin A1
chr1_-_209806124 0.61 ENST00000367021.8
ENST00000542854.5
IRF6
interferon regulatory factor 6
chr14_-_23154422 0.57 ENST00000422941.6
SLC7A8
solute carrier family 7 member 8
chr15_+_45129933 0.57 ENST00000321429.8
ENST00000389037.7
ENST00000558322.5
DUOX1
dual oxidase 1
chr11_+_1839602 0.54 ENST00000617947.4
ENST00000252898.11
TNNI2
troponin I2, fast skeletal type
chr14_-_91867529 0.53 ENST00000435962.7
TC2N
tandem C2 domains, nuclear
chr17_+_75754618 0.53 ENST00000584939.1
ITGB4
integrin subunit beta 4
chr15_-_72320149 0.53 ENST00000287202.10
CELF6
CUGBP Elav-like family member 6
chr19_+_45340774 0.53 ENST00000589837.5
KLC3
kinesin light chain 3
chr15_-_82952683 0.52 ENST00000450735.7
ENST00000304231.12
HOMER2
homer scaffold protein 2
chr9_-_137054016 0.51 ENST00000312665.7
ENST00000355097.7
ENTPD2
ectonucleoside triphosphate diphosphohydrolase 2
chr7_+_73830988 0.51 ENST00000340958.4
CLDN4
claudin 4
chr7_+_86643902 0.49 ENST00000361669.7
GRM3
glutamate metabotropic receptor 3
chr11_-_72722302 0.48 ENST00000334211.12
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr12_+_56080155 0.48 ENST00000267101.8
ERBB3
erb-b2 receptor tyrosine kinase 3
chr14_-_99272184 0.48 ENST00000357195.8
BCL11B
BAF chromatin remodeling complex subunit BCL11B
chr3_+_46987972 0.48 ENST00000651747.1
NBEAL2
neurobeachin like 2
chr8_+_144509049 0.47 ENST00000301327.5
MFSD3
major facilitator superfamily domain containing 3
chr2_-_20225433 0.47 ENST00000381150.5
SDC1
syndecan 1
chr8_+_122781621 0.47 ENST00000314393.6
ZHX2
zinc fingers and homeoboxes 2
chr11_+_60924452 0.47 ENST00000453848.7
ENST00000544065.5
ENST00000005286.8
TMEM132A
transmembrane protein 132A
chr14_-_23154369 0.47 ENST00000453702.5
SLC7A8
solute carrier family 7 member 8
chr3_+_50155024 0.46 ENST00000414301.5
ENST00000450338.5
ENST00000413852.5
SEMA3F
semaphorin 3F
chr1_-_28193873 0.46 ENST00000305392.3
ENST00000539896.1
PTAFR
platelet activating factor receptor
chr1_+_65147514 0.46 ENST00000545314.5
AK4
adenylate kinase 4
chr16_+_66880503 0.46 ENST00000568869.1
ENST00000311765.4
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chrX_-_153875847 0.46 ENST00000361699.8
ENST00000361981.7
L1CAM
L1 cell adhesion molecule
chr19_+_38789198 0.45 ENST00000314980.5
LGALS7B
galectin 7B
chr12_-_84911178 0.44 ENST00000681688.1
SLC6A15
solute carrier family 6 member 15
chr6_+_79631322 0.44 ENST00000369838.6
SH3BGRL2
SH3 domain binding glutamate rich protein like 2
chr11_+_1838970 0.44 ENST00000381911.6
TNNI2
troponin I2, fast skeletal type
chr11_-_72721908 0.43 ENST00000426523.5
ENST00000429686.5
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chrX_-_153886132 0.42 ENST00000370055.5
ENST00000370060.7
ENST00000420165.5
L1CAM
L1 cell adhesion molecule
chr19_-_51026593 0.42 ENST00000600362.5
ENST00000453757.8
ENST00000601671.1
KLK11
kallikrein related peptidase 11
chr4_+_83535914 0.42 ENST00000611707.4
GPAT3
glycerol-3-phosphate acyltransferase 3
chr13_+_79481124 0.41 ENST00000612570.4
ENST00000218652.11
NDFIP2
Nedd4 family interacting protein 2
chr11_+_76860859 0.41 ENST00000679754.1
ENST00000534206.5
ENST00000680583.1
ENST00000532485.6
ENST00000526597.5
ENST00000533873.1
ACER3
alkaline ceramidase 3
chr19_-_43670153 0.41 ENST00000601723.5
ENST00000339082.7
ENST00000340093.8
PLAUR
plasminogen activator, urokinase receptor
chr11_+_121576760 0.40 ENST00000532694.5
ENST00000534286.5
SORL1
sortilin related receptor 1
chr19_-_11577632 0.40 ENST00000590420.1
ENST00000648477.1
ACP5
acid phosphatase 5, tartrate resistant
chr3_+_142623386 0.39 ENST00000337777.7
ENST00000497199.5
PLS1
plastin 1
chr3_-_171460368 0.39 ENST00000436636.7
ENST00000465393.1
ENST00000341852.10
TNIK
TRAF2 and NCK interacting kinase
chr1_+_13584262 0.39 ENST00000376061.8
ENST00000513143.5
PDPN
podoplanin
chr19_+_1067272 0.39 ENST00000590214.5
ARHGAP45
Rho GTPase activating protein 45
chr20_+_62667803 0.39 ENST00000451793.1
SLCO4A1
solute carrier organic anion transporter family member 4A1
chr4_+_83536097 0.38 ENST00000395226.6
ENST00000264409.5
GPAT3
glycerol-3-phosphate acyltransferase 3
chr19_-_51027662 0.37 ENST00000594768.5
KLK11
kallikrein related peptidase 11
chr6_+_30882914 0.37 ENST00000509639.5
ENST00000412274.6
ENST00000507901.5
ENST00000507046.5
ENST00000437124.6
ENST00000454612.6
ENST00000396342.6
DDR1
discoidin domain receptor tyrosine kinase 1
chr13_+_79481468 0.37 ENST00000620924.1
NDFIP2
Nedd4 family interacting protein 2
chr3_-_171460063 0.36 ENST00000284483.12
ENST00000475336.5
ENST00000357327.9
ENST00000460047.5
ENST00000488470.5
ENST00000470834.5
TNIK
TRAF2 and NCK interacting kinase
chr10_+_69451456 0.36 ENST00000373290.7
TSPAN15
tetraspanin 15
chr20_+_62656359 0.35 ENST00000370507.5
SLCO4A1
solute carrier organic anion transporter family member 4A1
chr2_+_74654228 0.35 ENST00000611975.4
ENST00000357877.7
ENST00000339773.9
ENST00000434486.5
SEMA4F
ssemaphorin 4F
chr13_+_79481446 0.34 ENST00000487865.5
NDFIP2
Nedd4 family interacting protein 2
chr4_-_154590735 0.34 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
FGA
fibrinogen alpha chain
chr6_+_142301926 0.34 ENST00000296932.13
ENST00000367609.8
ADGRG6
adhesion G protein-coupled receptor G6
chr10_+_46375721 0.33 ENST00000616785.1
ENST00000611655.1
ENST00000619162.5
ENSG00000285402.1
ANXA8L1
novel transcript
annexin A8 like 1
chr2_-_20225123 0.33 ENST00000254351.9
SDC1
syndecan 1
chr9_-_83063135 0.32 ENST00000376447.4
RASEF
RAS and EF-hand domain containing
chr11_+_120210991 0.30 ENST00000328965.9
OAF
out at first homolog
chr15_-_34367159 0.30 ENST00000314891.11
LPCAT4
lysophosphatidylcholine acyltransferase 4
chr6_+_142301854 0.30 ENST00000230173.10
ENST00000367608.6
ADGRG6
adhesion G protein-coupled receptor G6
chr15_-_34367045 0.29 ENST00000617710.4
LPCAT4
lysophosphatidylcholine acyltransferase 4
chr11_-_59212869 0.29 ENST00000361050.4
MPEG1
macrophage expressed 1
chr1_-_32901330 0.29 ENST00000329151.5
ENST00000373463.8
TMEM54
transmembrane protein 54
chr15_-_51751434 0.28 ENST00000558126.1
LYSMD2
LysM domain containing 2
chr3_-_134029914 0.28 ENST00000493729.5
ENST00000310926.11
SLCO2A1
solute carrier organic anion transporter family member 2A1
chr17_+_40015428 0.28 ENST00000394149.8
ENST00000225474.6
ENST00000331769.6
ENST00000394148.7
ENST00000577675.1
CSF3
colony stimulating factor 3
chr1_+_3454657 0.28 ENST00000378378.9
ARHGEF16
Rho guanine nucleotide exchange factor 16
chrX_+_153642473 0.27 ENST00000370167.8
DUSP9
dual specificity phosphatase 9
chr19_+_18173804 0.27 ENST00000407280.4
IFI30
IFI30 lysosomal thiol reductase
chr12_+_65169546 0.27 ENST00000308330.3
LEMD3
LEM domain containing 3
chr4_-_89836213 0.27 ENST00000618500.4
ENST00000508895.5
SNCA
synuclein alpha
chr8_+_22053543 0.26 ENST00000519850.5
ENST00000381470.7
DMTN
dematin actin binding protein
chr17_+_7439504 0.26 ENST00000575331.1
ENST00000293829.9
ENSG00000272884.1
FGF11
novel transcript
fibroblast growth factor 11
chr7_+_66205325 0.26 ENST00000304842.6
ENST00000649664.1
TPST1
tyrosylprotein sulfotransferase 1
chr19_+_39196956 0.25 ENST00000339852.5
NCCRP1
NCCRP1, F-box associated domain containing
chr1_-_115768702 0.25 ENST00000261448.6
CASQ2
calsequestrin 2
chr19_+_8053000 0.25 ENST00000390669.7
CCL25
C-C motif chemokine ligand 25
chr19_-_43780957 0.24 ENST00000648319.1
KCNN4
potassium calcium-activated channel subfamily N member 4
chr21_-_44928711 0.23 ENST00000517563.5
ITGB2
integrin subunit beta 2
chr22_-_19854807 0.23 ENST00000416337.1
ENST00000403325.5
ENST00000453108.1
RTL10
GNB1L
retrotransposon Gag like 10
G protein subunit beta 1 like
chr15_+_41838839 0.23 ENST00000458483.4
PLA2G4B
phospholipase A2 group IVB
chr12_+_49295138 0.23 ENST00000257860.9
PRPH
peripherin
chr19_-_9498596 0.23 ENST00000301480.5
ZNF560
zinc finger protein 560
chr18_+_58045642 0.23 ENST00000676223.1
ENST00000675147.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr1_+_206507546 0.22 ENST00000580449.5
ENST00000581503.6
RASSF5
Ras association domain family member 5
chr1_-_6485433 0.22 ENST00000535355.6
PLEKHG5
pleckstrin homology and RhoGEF domain containing G5
chr19_-_15898057 0.22 ENST00000011989.11
ENST00000221700.11
CYP4F2
cytochrome P450 family 4 subfamily F member 2
chr15_-_51751525 0.22 ENST00000454181.6
LYSMD2
LysM domain containing 2
chr2_+_29113989 0.22 ENST00000404424.5
CLIP4
CAP-Gly domain containing linker protein family member 4
chr1_-_204307391 0.22 ENST00000637508.1
PLEKHA6
pleckstrin homology domain containing A6
chr2_-_60550900 0.21 ENST00000643222.1
ENST00000643459.1
ENST00000489516.7
BCL11A
BAF chromatin remodeling complex subunit BCL11A
chr11_+_118956289 0.21 ENST00000264031.3
UPK2
uroplakin 2
chr5_+_136049513 0.21 ENST00000514554.5
TGFBI
transforming growth factor beta induced
chr15_-_75712828 0.21 ENST00000308508.5
CSPG4
chondroitin sulfate proteoglycan 4
chr19_+_8052315 0.20 ENST00000680646.1
CCL25
C-C motif chemokine ligand 25
chr1_+_15756659 0.20 ENST00000375771.5
FBLIM1
filamin binding LIM protein 1
chr19_+_8052335 0.20 ENST00000680507.1
ENST00000680450.1
ENST00000681526.1
ENST00000680506.1
CCL25
C-C motif chemokine ligand 25
chr19_+_8209300 0.20 ENST00000558268.5
ENST00000558331.5
CERS4
ceramide synthase 4
chr2_-_135985568 0.20 ENST00000264161.9
DARS1
aspartyl-tRNA synthetase 1
chr2_+_118088432 0.20 ENST00000245787.9
INSIG2
insulin induced gene 2
chr14_+_77181780 0.20 ENST00000298351.5
ENST00000554346.5
TMEM63C
transmembrane protein 63C
chr13_-_98977975 0.20 ENST00000376460.5
DOCK9
dedicator of cytokinesis 9
chr8_-_33567118 0.20 ENST00000256257.2
RNF122
ring finger protein 122
chr17_-_64130125 0.19 ENST00000680433.1
ENST00000433197.4
ERN1
endoplasmic reticulum to nucleus signaling 1
chr7_+_74209386 0.19 ENST00000344995.9
LAT2
linker for activation of T cells family member 2
chr17_+_16217198 0.19 ENST00000581006.5
ENST00000584797.5
ENST00000225609.10
ENST00000395844.8
ENST00000463810.2
PIGL
phosphatidylinositol glycan anchor biosynthesis class L
chr8_-_143617498 0.19 ENST00000425753.7
GFUS
GDP-L-fucose synthase
chr14_-_21023318 0.19 ENST00000298684.9
ENST00000557169.5
ENST00000553563.5
NDRG2
NDRG family member 2
chr11_+_77179750 0.19 ENST00000458169.2
MYO7A
myosin VIIA
chrX_-_153944621 0.18 ENST00000393700.8
RENBP
renin binding protein
chr18_-_63661884 0.18 ENST00000332821.8
ENST00000283752.10
SERPINB3
serpin family B member 3
chr3_-_195892706 0.18 ENST00000673038.1
ENST00000678220.1
ENST00000428187.7
TNK2
tyrosine kinase non receptor 2
chr15_-_42273454 0.18 ENST00000448392.5
TMEM87A
transmembrane protein 87A
chr19_+_8052752 0.18 ENST00000315626.6
ENST00000253451.9
CCL25
C-C motif chemokine ligand 25
chr21_-_46142701 0.18 ENST00000494498.2
FTCD
formimidoyltransferase cyclodeaminase
chr1_+_207321668 0.18 ENST00000367064.9
ENST00000314754.12
ENST00000367067.8
ENST00000644836.1
ENST00000343420.6
CD55
CD55 molecule (Cromer blood group)
chr19_+_8209320 0.18 ENST00000561053.5
ENST00000559450.5
ENST00000251363.10
ENST00000559336.5
CERS4
ceramide synthase 4
chr21_-_44262216 0.17 ENST00000270172.7
DNMT3L
DNA methyltransferase 3 like
chrX_-_153944655 0.17 ENST00000369997.7
RENBP
renin binding protein
chr18_+_44697118 0.17 ENST00000677077.1
SETBP1
SET binding protein 1
chr8_+_144358974 0.17 ENST00000526891.2
SLC52A2
solute carrier family 52 member 2
chr22_+_20967212 0.17 ENST00000434714.6
AIFM3
apoptosis inducing factor mitochondria associated 3
chr17_-_75289212 0.17 ENST00000582778.1
ENST00000581988.5
ENST00000579207.5
ENST00000583332.5
ENST00000442286.6
ENST00000580151.5
ENST00000580994.5
ENST00000584438.1
ENST00000416858.7
ENST00000320362.7
SLC25A19
solute carrier family 25 member 19
chr12_-_214146 0.17 ENST00000684302.1
SLC6A12
solute carrier family 6 member 12
chr10_-_112183698 0.17 ENST00000369425.5
ENST00000348367.9
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr22_+_20967243 0.17 ENST00000683034.1
ENST00000440238.4
ENST00000405089.5
AIFM3
apoptosis inducing factor mitochondria associated 3
chr12_-_101830799 0.17 ENST00000549940.5
ENST00000392919.4
GNPTAB
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
chr12_-_213656 0.17 ENST00000359674.8
SLC6A12
solute carrier family 6 member 12
chr5_+_148063971 0.17 ENST00000398454.5
ENST00000359874.7
ENST00000508733.5
ENST00000256084.8
SPINK5
serine peptidase inhibitor Kazal type 5
chr11_-_114595777 0.17 ENST00000375478.4
NXPE4
neurexophilin and PC-esterase domain family member 4
chr11_+_1410443 0.17 ENST00000528710.5
BRSK2
BR serine/threonine kinase 2
chr10_-_42638551 0.17 ENST00000493285.2
ENST00000359467.8
ZNF33B
zinc finger protein 33B
chr11_-_114595750 0.16 ENST00000424261.6
NXPE4
neurexophilin and PC-esterase domain family member 4
chr3_-_130746760 0.16 ENST00000356763.8
PIK3R4
phosphoinositide-3-kinase regulatory subunit 4
chr11_+_6205549 0.16 ENST00000316375.3
C11orf42
chromosome 11 open reading frame 42
chr1_+_207321532 0.16 ENST00000367063.6
ENST00000391921.9
ENST00000645323.1
CD55
CD55 molecule (Cromer blood group)
chr8_-_143617457 0.16 ENST00000529048.5
ENST00000529064.5
GFUS
GDP-L-fucose synthase
chr16_+_46689640 0.16 ENST00000219097.7
ENST00000568364.6
ORC6
origin recognition complex subunit 6
chr17_-_29761390 0.16 ENST00000324677.12
SSH2
slingshot protein phosphatase 2
chr6_+_37257762 0.16 ENST00000373491.3
TBC1D22B
TBC1 domain family member 22B
chr13_-_46438190 0.16 ENST00000409879.6
RUBCNL
rubicon like autophagy enhancer
chr3_-_14124816 0.16 ENST00000295767.9
ENST00000396914.4
CHCHD4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr2_-_25982471 0.16 ENST00000264712.8
KIF3C
kinesin family member 3C
chr15_-_42273408 0.16 ENST00000389834.9
ENST00000307216.10
TMEM87A
transmembrane protein 87A
chr6_-_132714045 0.15 ENST00000367928.5
VNN1
vanin 1
chr15_-_62165274 0.15 ENST00000380392.4
C2CD4B
C2 calcium dependent domain containing 4B
chr6_-_20212403 0.15 ENST00000324607.8
MBOAT1
membrane bound O-acyltransferase domain containing 1
chr17_+_49132763 0.15 ENST00000393354.7
B4GALNT2
beta-1,4-N-acetyl-galactosaminyltransferase 2
chr8_-_10655137 0.15 ENST00000382483.4
RP1L1
RP1 like 1
chr1_+_99970430 0.15 ENST00000370153.6
SLC35A3
solute carrier family 35 member A3
chr14_+_103100328 0.15 ENST00000559116.1
EXOC3L4
exocyst complex component 3 like 4
chr19_+_37371152 0.15 ENST00000483919.5
ENST00000588911.5
ENST00000587349.1
ZNF527
zinc finger protein 527
chr2_-_55917699 0.15 ENST00000634374.1
EFEMP1
EGF containing fibulin extracellular matrix protein 1
chr19_+_15640880 0.15 ENST00000586182.6
ENST00000221307.13
ENST00000591058.5
CYP4F3
cytochrome P450 family 4 subfamily F member 3
chr12_+_52010485 0.15 ENST00000552049.5
ENST00000546756.1
TAMALIN
trafficking regulator and scaffold protein tamalin
chr22_+_31082860 0.15 ENST00000619644.4
SMTN
smoothelin
chr10_-_97401277 0.15 ENST00000315563.10
ENST00000370992.9
ENST00000414986.5
RRP12
ribosomal RNA processing 12 homolog
chr17_-_39166138 0.15 ENST00000269586.12
ARL5C
ADP ribosylation factor like GTPase 5C
chr19_-_43781249 0.14 ENST00000615047.4
KCNN4
potassium calcium-activated channel subfamily N member 4
chr14_-_24299707 0.14 ENST00000288111.12
DHRS1
dehydrogenase/reductase 1
chr12_+_48122574 0.14 ENST00000549022.5
ENST00000547587.5
ENST00000312352.11
PFKM
phosphofructokinase, muscle

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.5 2.9 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.5 1.9 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.3 1.3 GO:0032595 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.2 0.9 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.2 1.7 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.2 1.5 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.2 0.8 GO:0048627 myoblast development(GO:0048627)
0.2 0.9 GO:0097021 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.2 1.1 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 0.6 GO:0042335 cuticle development(GO:0042335)
0.1 0.4 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.4 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.4 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.4 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.2 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 1.0 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.1 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.1 0.3 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.5 GO:1902943 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) regulation of leukocyte tethering or rolling(GO:1903236) positive regulation of leukocyte tethering or rolling(GO:1903238)
0.1 0.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.4 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 0.8 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.3 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.2 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.1 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.2 GO:1904800 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.6 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.8 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.2 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.5 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.3 GO:0051620 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.2 GO:2000213 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 1.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.3 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.0 0.0 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.0 1.5 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.9 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.2 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.0 0.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.9 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.4 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.5 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.2 GO:1901523 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.5 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0060458 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.5 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.4 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 1.0 GO:0015695 organic cation transport(GO:0015695)
0.0 0.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.2 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.3 GO:0086068 Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.0 0.3 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.4 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.0 0.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.6 GO:0007620 copulation(GO:0007620)
0.0 0.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.6 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.8 GO:0007141 male meiosis I(GO:0007141)
0.0 1.8 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.7 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.8 GO:0097435 fibril organization(GO:0097435)
0.0 0.1 GO:0036245 cellular response to menadione(GO:0036245)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 2.2 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.1 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.3 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258) negative regulation of type B pancreatic cell development(GO:2000077)
0.0 0.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.2 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 1.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.2 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.0 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 1.0 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.3 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 0.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 GO:0043203 axon hillock(GO:0043203)
0.2 1.0 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.2 0.8 GO:0072534 perineuronal net(GO:0072534)
0.2 0.6 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.1 2.0 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.7 GO:0032010 phagolysosome(GO:0032010)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.0 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 1.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.9 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.0 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0005605 basal lamina(GO:0005605)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.2 1.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.6 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.8 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.4 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.4 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 2.9 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 0.5 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.3 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 1.0 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.4 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 1.0 GO:0019534 toxin transporter activity(GO:0019534)
0.1 1.0 GO:0031014 troponin T binding(GO:0031014)
0.1 1.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.5 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.2 GO:0090422 thiamine pyrophosphate transporter activity(GO:0090422)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.2 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.1 1.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.0 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.8 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 1.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.9 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 2.0 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.4 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.4 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0001626 nociceptin receptor activity(GO:0001626)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 5.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.0 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.5 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.0 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.4 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.0 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 3.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.2 REACTOME KINESINS Genes involved in Kinesins
0.1 1.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.1 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 1.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling