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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for KLF6

Z-value: 0.98

Motif logo

Transcription factors associated with KLF6

Gene Symbol Gene ID Gene Info
ENSG00000067082.15 Kruppel like factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF6hg38_v1_chr10_-_3785197_37852160.078.6e-01Click!

Activity profile of KLF6 motif

Sorted Z-values of KLF6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_159171607 1.32 ENST00000368124.8
ENST00000368125.9
ENST00000416746.1
cell adhesion molecule 3
chr14_-_29927596 1.21 ENST00000415220.6
protein kinase D1
chr14_-_29927473 0.94 ENST00000616995.4
protein kinase D1
chr14_-_29927801 0.91 ENST00000331968.11
protein kinase D1
chr5_+_93584916 0.85 ENST00000647447.1
ENST00000615873.1
nuclear receptor subfamily 2 group F member 1
chr14_-_59630806 0.81 ENST00000342503.8
reticulon 1
chr14_-_59630582 0.80 ENST00000395090.5
reticulon 1
chr5_+_68215738 0.77 ENST00000521381.6
ENST00000521657.5
phosphoinositide-3-kinase regulatory subunit 1
chr1_+_113979460 0.76 ENST00000320334.5
olfactomedin like 3
chr1_+_113979391 0.76 ENST00000393300.6
ENST00000369551.5
olfactomedin like 3
chr2_-_127107259 0.73 ENST00000409400.1
ENST00000357970.7
ENST00000393040.7
ENST00000348750.8
ENST00000259238.8
ENST00000346226.7
ENST00000393041.7
ENST00000351659.7
ENST00000352848.7
bridging integrator 1
chr4_-_2262082 0.66 ENST00000337190.7
MAX dimerization protein 4
chr6_+_71886900 0.65 ENST00000517960.5
ENST00000518273.5
ENST00000522291.5
ENST00000521978.5
ENST00000520567.5
ENST00000264839.11
regulating synaptic membrane exocytosis 1
chr9_-_117415032 0.65 ENST00000361477.8
ENST00000313400.9
ENST00000361209.6
astrotactin 2
chr2_+_240998608 0.63 ENST00000310397.13
sushi, nidogen and EGF like domains 1
chr11_+_114059755 0.62 ENST00000684295.1
zinc finger and BTB domain containing 16
chr15_-_48645701 0.61 ENST00000316623.10
ENST00000560355.1
fibrillin 1
chr6_-_30742203 0.56 ENST00000416018.5
ENST00000445853.5
ENST00000413165.5
ENST00000418160.5
flotillin 1
chr6_-_52577012 0.55 ENST00000182527.4
translocation associated membrane protein 2
chr11_+_114059702 0.55 ENST00000335953.9
ENST00000684612.1
ENST00000682810.1
ENST00000544220.1
zinc finger and BTB domain containing 16
chr6_-_30742486 0.54 ENST00000438162.5
ENST00000454845.1
flotillin 1
chr11_-_65872728 0.52 ENST00000528176.5
ENST00000307998.11
EGF containing fibulin extracellular matrix protein 2
chr17_-_44199206 0.51 ENST00000589805.1
ataxin 7 like 3
chr2_-_127107144 0.51 ENST00000316724.10
bridging integrator 1
chr13_+_31846713 0.51 ENST00000645780.1
FRY microtubule binding protein
chr1_-_182391323 0.50 ENST00000642379.1
glutamate-ammonia ligase
chr2_+_32946944 0.49 ENST00000404816.7
latent transforming growth factor beta binding protein 1
chr15_+_32717994 0.47 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
gremlin 1, DAN family BMP antagonist
chr5_+_40679907 0.46 ENST00000302472.4
prostaglandin E receptor 4
chr16_+_29812230 0.46 ENST00000300797.7
ENST00000637403.1
ENST00000572820.2
ENST00000637064.1
ENST00000636246.1
proline rich transmembrane protein 2
chr5_-_108381109 0.45 ENST00000619412.4
F-box and leucine rich repeat protein 17
chr20_-_49482645 0.44 ENST00000371741.6
potassium voltage-gated channel subfamily B member 1
chr8_+_17027230 0.44 ENST00000318063.10
mitochondrial calcium uptake family member 3
chr5_-_81751085 0.42 ENST00000515395.5
single stranded DNA binding protein 2
chr9_+_36036899 0.42 ENST00000377966.4
reversion inducing cysteine rich protein with kazal motifs
chr19_+_49527988 0.41 ENST00000270645.8
reticulocalbin 3
chr6_-_30742670 0.40 ENST00000376389.8
flotillin 1
chr2_-_229271221 0.40 ENST00000392054.7
ENST00000409462.1
ENST00000392055.8
phosphotyrosine interaction domain containing 1
chr5_-_81751022 0.39 ENST00000509013.2
ENST00000505980.5
ENST00000509053.5
single stranded DNA binding protein 2
chr19_-_31349408 0.39 ENST00000240587.5
teashirt zinc finger homeobox 3
chr17_-_7242156 0.39 ENST00000571129.5
ENST00000571253.1
ENST00000573928.1
ENST00000302386.10
GABA type A receptor-associated protein
chr19_-_1401487 0.39 ENST00000640762.1
ENST00000252288.8
ENST00000447102.8
guanidinoacetate N-methyltransferase
chr2_+_23385170 0.39 ENST00000486442.6
kelch like family member 29
chr12_-_48004496 0.37 ENST00000337299.7
collagen type II alpha 1 chain
chr5_-_81751103 0.36 ENST00000514493.5
ENST00000320672.8
ENST00000615665.4
single stranded DNA binding protein 2
chrX_-_19122457 0.36 ENST00000357991.7
ENST00000356606.8
ENST00000379869.8
adhesion G protein-coupled receptor G2
chr2_+_30146993 0.36 ENST00000261353.9
ENST00000402003.7
yippee like 5
chr2_+_30146941 0.36 ENST00000379520.7
ENST00000379519.7
yippee like 5
chr2_+_148021083 0.36 ENST00000642680.2
methyl-CpG binding domain protein 5
chr2_+_148021001 0.35 ENST00000407073.5
methyl-CpG binding domain protein 5
chr11_+_62613236 0.34 ENST00000278833.4
retinal outer segment membrane protein 1
chr6_+_56955097 0.33 ENST00000370746.8
ENST00000370748.7
BEN domain containing 6
chr6_-_169723931 0.33 ENST00000366780.8
ENST00000612128.1
PHD finger protein 10
chr10_+_74825445 0.33 ENST00000649006.1
ENST00000649463.1
ENST00000372725.6
lysine acetyltransferase 6B
chr10_+_74826550 0.33 ENST00000649657.1
ENST00000372714.6
ENST00000649442.1
ENST00000648539.1
ENST00000647666.1
ENST00000648048.1
ENST00000287239.10
ENST00000649375.1
lysine acetyltransferase 6B
chr12_-_92145838 0.33 ENST00000256015.5
BTG anti-proliferation factor 1
chr6_-_31729785 0.32 ENST00000416410.6
dimethylarginine dimethylaminohydrolase 2
chr16_+_29812150 0.32 ENST00000647876.1
ENST00000567551.2
ENST00000567659.3
ENST00000637565.1
ENST00000358758.12
ENST00000636619.1
proline rich transmembrane protein 2
chr17_-_30291930 0.30 ENST00000261714.11
bleomycin hydrolase
chr4_+_4859658 0.30 ENST00000382723.5
msh homeobox 1
chr6_+_71886703 0.29 ENST00000491071.6
regulating synaptic membrane exocytosis 1
chr10_+_71212524 0.28 ENST00000335350.10
unc-5 netrin receptor B
chr5_+_134526176 0.28 ENST00000681820.1
ENST00000512386.6
ENST00000612830.2
jade family PHD finger 2
chr2_+_24491239 0.28 ENST00000348332.8
nuclear receptor coactivator 1
chr11_+_118607598 0.27 ENST00000600882.6
ENST00000356063.9
pleckstrin homology like domain family B member 1
chr1_-_182391783 0.27 ENST00000331872.11
ENST00000339526.8
glutamate-ammonia ligase
chr19_+_10086305 0.27 ENST00000253110.16
ENST00000591813.5
shiftless antiviral inhibitor of ribosomal frameshifting
chr10_+_93993897 0.27 ENST00000371380.8
phospholipase C epsilon 1
chr11_-_417304 0.26 ENST00000397632.7
single Ig and TIR domain containing
chr17_+_45221993 0.26 ENST00000328118.7
formin like 1
chr10_+_74826406 0.26 ENST00000648892.1
ENST00000647890.1
ENST00000372724.6
lysine acetyltransferase 6B
chr3_+_111071773 0.26 ENST00000485303.6
nectin cell adhesion molecule 3
chr16_+_69566314 0.26 ENST00000565301.2
nuclear factor of activated T cells 5
chr1_+_33256479 0.26 ENST00000539719.6
ENST00000483388.5
zinc finger protein 362
chr1_+_6785518 0.26 ENST00000467404.6
calmodulin binding transcription activator 1
chr6_-_35688907 0.26 ENST00000539068.5
ENST00000357266.9
FKBP prolyl isomerase 5
chr6_+_32844108 0.26 ENST00000458296.2
ENST00000413039.6
ENST00000412095.1
ENST00000395330.5
PSMB8 antisense RNA 1 (head to head)
proteasome 20S subunit beta 9
chr4_-_39527429 0.26 ENST00000501493.6
ENST00000509391.1
ENST00000316423.11
ENST00000507089.5
UDP-glucose 6-dehydrogenase
chr8_-_56211257 0.26 ENST00000316981.8
ENST00000423799.6
ENST00000429357.2
PLAG1 zinc finger
chr1_+_160205411 0.25 ENST00000368076.1
proliferation and apoptosis adaptor protein 15
chr13_+_97434154 0.25 ENST00000245304.5
RAP2A, member of RAS oncogene family
chr3_-_51967410 0.25 ENST00000461554.6
ENST00000483411.5
ENST00000461544.2
ENST00000355852.6
poly(rC) binding protein 4
chr1_-_38005484 0.25 ENST00000373016.4
four and a half LIM domains 3
chr7_-_28958321 0.25 ENST00000539664.3
TLR4 interactor with leucine rich repeats
chr19_-_40425982 0.25 ENST00000357949.5
SERTA domain containing 1
chr16_+_69566041 0.25 ENST00000567239.5
nuclear factor of activated T cells 5
chr1_-_182391363 0.25 ENST00000417584.6
glutamate-ammonia ligase
chr7_-_139777986 0.25 ENST00000406875.8
homeodomain interacting protein kinase 2
chr11_+_117199363 0.25 ENST00000392951.9
ENST00000525531.5
ENST00000278968.10
transgelin
chr1_+_154325512 0.24 ENST00000368489.6
ENST00000368487.7
ATPase phospholipid transporting 8B2
chr18_-_56638427 0.24 ENST00000586262.5
ENST00000217515.11
thioredoxin like 1
chr7_-_28180735 0.24 ENST00000283928.10
JAZF zinc finger 1
chr11_+_118607579 0.24 ENST00000530708.4
pleckstrin homology like domain family B member 1
chr22_-_17121311 0.24 ENST00000331437.4
ENST00000399875.1
transmembrane protein 121B
chr16_-_57536543 0.24 ENST00000258214.3
coiled-coil domain containing 102A
chrX_+_54808334 0.24 ENST00000218439.8
MAGE family member D2
chr16_-_30122944 0.23 ENST00000484663.5
ENST00000478356.5
mitogen-activated protein kinase 3
chr15_-_82647503 0.23 ENST00000567678.1
ENST00000620182.4
cytoplasmic polyadenylation element binding protein 1
chr6_+_122610391 0.23 ENST00000368452.7
cAMP-dependent protein kinase inhibitor beta
chr5_+_173056345 0.23 ENST00000522692.5
ENST00000296953.6
ENST00000520420.5
CREB3 regulatory factor
chr20_+_58891691 0.23 ENST00000468895.6
GNAS complex locus
chr16_-_30123203 0.23 ENST00000395202.5
ENST00000395199.7
ENST00000263025.9
ENST00000322266.9
mitogen-activated protein kinase 3
chr16_+_29806519 0.23 ENST00000322945.11
ENST00000562337.5
ENST00000566906.6
ENST00000563402.1
ENST00000219782.10
MYC associated zinc finger protein
chr2_+_24491860 0.23 ENST00000406961.5
ENST00000405141.5
nuclear receptor coactivator 1
chr17_+_83079595 0.22 ENST00000320095.12
meteorin like, glial cell differentiation regulator
chr2_+_235494024 0.22 ENST00000304032.13
ENST00000409457.5
ENST00000336665.9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr2_-_179264757 0.22 ENST00000428443.8
SEC14 and spectrin domain containing 1
chr15_-_82647960 0.22 ENST00000615198.4
cytoplasmic polyadenylation element binding protein 1
chr17_+_57256514 0.22 ENST00000284073.7
ENST00000674964.1
musashi RNA binding protein 2
chr6_+_11537738 0.22 ENST00000379426.2
transmembrane protein 170B
chr2_-_37672178 0.22 ENST00000457889.1
CDC42 effector protein 3
chr17_-_38799442 0.22 ENST00000619039.5
phosphatidylinositol-5-phosphate 4-kinase type 2 beta
chr6_+_33428223 0.22 ENST00000682587.1
synaptic Ras GTPase activating protein 1
chr1_+_210232776 0.22 ENST00000367012.4
SERTA domain containing 4
chr15_+_43510945 0.21 ENST00000382031.5
microtubule associated protein 1A
chr7_-_122886706 0.21 ENST00000313070.11
ENST00000334010.11
ENST00000615869.4
calcium dependent secretion activator 2
chr4_+_128811311 0.21 ENST00000413543.6
jade family PHD finger 1
chr19_-_14090695 0.21 ENST00000533683.7
sterile alpha motif domain containing 1
chr20_+_34876603 0.21 ENST00000360596.7
ENST00000253382.5
acyl-CoA synthetase short chain family member 2
chr17_-_35089212 0.21 ENST00000584655.5
ENST00000447669.6
ENST00000315249.11
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr11_+_45885625 0.21 ENST00000241014.6
mitogen-activated protein kinase 8 interacting protein 1
chr19_+_40601342 0.21 ENST00000396819.8
latent transforming growth factor beta binding protein 4
chr8_+_22551917 0.21 ENST00000240123.12
sorbin and SH3 domain containing 3
chr15_+_43791842 0.20 ENST00000674451.1
ENST00000630046.2
small EDRK-rich factor 2
chr3_+_143119749 0.20 ENST00000309575.5
carbohydrate sulfotransferase 2
chr4_+_128811264 0.20 ENST00000610919.4
ENST00000510308.5
jade family PHD finger 1
chr16_+_23557714 0.20 ENST00000567212.5
ENST00000567264.1
ENST00000395878.8
ubiquitin family domain containing 1
chrX_+_54809060 0.20 ENST00000396224.1
MAGE family member D2
chrX_+_54808359 0.20 ENST00000375058.5
ENST00000375060.5
MAGE family member D2
chr20_+_36306325 0.20 ENST00000373913.7
ENST00000339266.10
DLG associated protein 4
chr7_+_143381907 0.20 ENST00000392910.6
zyxin
chr17_+_43025203 0.20 ENST00000587250.4
Rho family GTPase 2
chr5_+_138753412 0.20 ENST00000520339.5
ENST00000627109.2
ENST00000302763.12
ENST00000518910.5
catenin alpha 1
chr21_+_43865200 0.20 ENST00000291572.13
1-acylglycerol-3-phosphate O-acyltransferase 3
chr11_+_64234569 0.20 ENST00000309422.7
ENST00000426086.3
vascular endothelial growth factor B
chr1_+_6785437 0.19 ENST00000303635.12
ENST00000473578.5
ENST00000557126.5
calmodulin binding transcription activator 1
chr11_-_66049120 0.19 ENST00000312006.5
galactose-3-O-sulfotransferase 3
chr5_+_134526100 0.19 ENST00000395003.5
jade family PHD finger 2
chr11_+_66278160 0.19 ENST00000311445.7
ENST00000528852.5
cornichon family AMPA receptor auxiliary protein 2
chr14_+_28766755 0.19 ENST00000313071.7
forkhead box G1
chr2_-_218568291 0.19 ENST00000418019.5
ENST00000454775.5
ENST00000338465.5
ENST00000415516.5
ENST00000258399.8
ubiquitin specific peptidase 37
chr2_-_101151253 0.19 ENST00000376840.8
ENST00000409318.2
TBC1 domain family member 8
chr2_-_73233206 0.19 ENST00000258083.3
protease associated domain containing 1
chr11_-_560702 0.19 ENST00000441853.5
ENST00000329451.8
lamin tail domain containing 2
chr20_+_58891738 0.19 ENST00000682803.1
GNAS complex locus
chr14_+_104724221 0.19 ENST00000330877.7
adenylosuccinate synthase 1
chr4_-_7939789 0.18 ENST00000420658.6
ENST00000358461.6
actin filament associated protein 1
chr21_-_26845402 0.18 ENST00000284984.8
ENST00000676955.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr15_+_64095967 0.18 ENST00000559844.6
ENST00000261889.9
ENST00000625244.2
ENST00000561026.5
ENST00000558040.5
sorting nexin 1
chr8_+_28338640 0.18 ENST00000522209.1
prepronociceptin
chr20_-_63831214 0.18 ENST00000302995.2
ENST00000245663.9
zinc finger and BTB domain containing 46
chr8_+_56211686 0.18 ENST00000521831.5
ENST00000303759.3
ENST00000517636.5
ENST00000517933.5
ENST00000355315.8
ENST00000518801.5
ENST00000523975.5
ENST00000396723.9
ENST00000523061.5
ENST00000521524.5
coiled-coil-helix-coiled-coil-helix domain containing 7
chr1_+_153658687 0.18 ENST00000368685.6
SNAP associated protein
chr17_+_57257002 0.18 ENST00000322684.7
ENST00000579590.5
musashi RNA binding protein 2
chr12_+_55743283 0.18 ENST00000546799.1
growth differentiation factor 11
chr17_-_21253398 0.18 ENST00000611551.1
N-acetyltransferase domain containing 1
chr9_+_128276222 0.18 ENST00000608796.6
ENST00000419867.7
ENST00000418976.2
SWI5 homologous recombination repair protein
chr11_+_66002475 0.17 ENST00000312175.7
ENST00000533166.5
BAF nuclear assembly factor 1
chrX_-_150898779 0.17 ENST00000613030.4
ENST00000437787.6
CD99 molecule like 2
chr20_+_3889377 0.17 ENST00000610179.7
pantothenate kinase 2
chr11_-_62754141 0.17 ENST00000527994.1
ENST00000394807.5
ENST00000673933.1
zinc finger and BTB domain containing 3
chr9_+_35605277 0.17 ENST00000620767.4
testis associated actin remodelling kinase 1
chr16_+_30395400 0.17 ENST00000320159.2
ENST00000613509.2
zinc finger protein 48
chr5_+_134525649 0.17 ENST00000282605.8
ENST00000681547.2
ENST00000361895.6
ENST00000402835.5
jade family PHD finger 2
chr2_+_46542474 0.17 ENST00000238738.9
ras homolog family member Q
chr18_-_63319987 0.17 ENST00000398117.1
BCL2 apoptosis regulator
chr15_-_64703199 0.17 ENST00000559753.1
ENST00000560258.6
ENST00000559912.2
ENST00000326005.10
ornithine decarboxylase antizyme 2
chr9_+_35605234 0.17 ENST00000336395.6
testis associated actin remodelling kinase 1
chr5_-_177497561 0.17 ENST00000359895.6
ENST00000355572.6
ENST00000393551.5
ENST00000505074.5
ENST00000393546.8
ENST00000355841.7
PDZ and LIM domain 7
chrX_+_151694967 0.17 ENST00000448726.5
ENST00000538575.5
proline rich and Gla domain 3
chr19_-_38899529 0.17 ENST00000249396.12
ENST00000437828.5
sirtuin 2
chr2_-_202238558 0.17 ENST00000392244.7
ENST00000409181.1
ENST00000409712.5
ENST00000409498.6
ENST00000409368.5
ENST00000392246.7
ENST00000392245.5
small ubiquitin like modifier 1
chr2_-_202238462 0.17 ENST00000409205.5
small ubiquitin like modifier 1
chr10_+_97498881 0.17 ENST00000370664.4
ubiquitin domain containing 1
chr1_+_26993684 0.17 ENST00000522111.3
TMF1 regulated nuclear protein 1
chr11_-_9265302 0.16 ENST00000328194.8
DENN domain containing 5A
chr3_-_48662877 0.16 ENST00000164024.5
cadherin EGF LAG seven-pass G-type receptor 3
chr5_-_38556625 0.16 ENST00000506990.5
ENST00000453190.7
LIF receptor subunit alpha
chr11_-_94973541 0.16 ENST00000279839.8
CWC15 spliceosome associated protein homolog
chr12_+_57089094 0.16 ENST00000342556.6
ENST00000300131.8
NGFI-A binding protein 2
chr15_-_83207800 0.16 ENST00000299633.7
HDGF like 3
chr1_+_42682954 0.16 ENST00000436427.1
Y-box binding protein 1
chr1_-_19485502 0.16 ENST00000264203.7
ENST00000375144.6
ENST00000674432.1
ENST00000264202.8
capping actin protein of muscle Z-line subunit beta
chr2_+_46699241 0.16 ENST00000394861.3
suppressor of cytokine signaling 5
chr17_+_38870050 0.16 ENST00000318008.11
ENST00000435347.7
LIM and SH3 protein 1
chr3_-_15859771 0.15 ENST00000399451.6
ankyrin repeat domain 28
chr6_-_56954747 0.15 ENST00000680361.1
dystonin
chr11_-_2885728 0.15 ENST00000647251.1
ENST00000380725.2
ENST00000430149.3
ENST00000414822.8
ENST00000440480.8
cyclin dependent kinase inhibitor 1C
chr1_-_11691608 0.15 ENST00000376667.7
mitotic arrest deficient 2 like 2
chr1_-_11691646 0.15 ENST00000235310.7
mitotic arrest deficient 2 like 2
chr1_+_210329294 0.15 ENST00000367010.5
hedgehog acyltransferase
chr6_-_32843994 0.15 ENST00000395339.7
ENST00000374882.8
proteasome 20S subunit beta 8
chr10_+_110871789 0.15 ENST00000393104.6
programmed cell death 4
chr15_+_75843438 0.15 ENST00000267938.9
ubiquitin conjugating enzyme E2 Q2
chr20_+_58891981 0.15 ENST00000488652.6
ENST00000476935.6
ENST00000492907.6
ENST00000603546.2
GNAS complex locus
chr14_-_100587404 0.15 ENST00000554140.2
brain enriched guanylate kinase associated
chr12_+_6766353 0.15 ENST00000309083.8
ENST00000389462.8
parathymosin
chr2_+_218399838 0.15 ENST00000273062.7
CTD small phosphatase 1
chr7_-_27130182 0.15 ENST00000511914.1
homeobox A4
chr12_+_8914525 0.15 ENST00000543824.5
polyhomeotic homolog 1

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 2.8 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 1.2 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.2 0.5 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.2 0.5 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.2 0.5 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.2 1.4 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 1.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.8 GO:0060988 lipid tube assembly(GO:0060988)
0.1 0.5 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.7 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.2 GO:0060434 bronchus morphogenesis(GO:0060434)
0.1 0.6 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 0.4 GO:2001170 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) negative regulation of ATP biosynthetic process(GO:2001170)
0.1 0.2 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.4 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.3 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.5 GO:0000189 MAPK import into nucleus(GO:0000189)
0.1 0.3 GO:0090427 embryonic nail plate morphogenesis(GO:0035880) activation of meiosis(GO:0090427)
0.1 0.2 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.3 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.2 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.1 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.3 GO:0043418 homocysteine catabolic process(GO:0043418)
0.1 0.2 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 0.2 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 0.7 GO:0030578 PML body organization(GO:0030578)
0.1 0.8 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.2 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.5 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 0.8 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.4 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.0 0.1 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.3 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.4 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.2 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.1 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.9 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.9 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828) cardiac cell fate determination(GO:0060913)
0.0 0.7 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.1 GO:0034553 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.2 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.4 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0071484 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0071878 negative regulation of adrenergic receptor signaling pathway(GO:0071878)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.0 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.1 GO:0009996 negative regulation of cell fate specification(GO:0009996)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0060382 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.0 0.3 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.3 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.0 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:0072034 renal vesicle induction(GO:0072034)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.1 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.1 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.1 GO:1903384 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.0 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.4 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.3 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.0 0.0 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:1901909 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934) protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.0 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.3 GO:0033233 regulation of protein sumoylation(GO:0033233)
0.0 0.0 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.3 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.0 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.2 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.0 GO:0071626 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.0 0.0 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.3 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.0 GO:0001922 B-1 B cell homeostasis(GO:0001922) neural fold elevation formation(GO:0021502)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0060987 lipid tube(GO:0060987)
0.2 0.7 GO:0060187 cell pole(GO:0060187)
0.2 0.8 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.3 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 1.4 GO:0016600 flotillin complex(GO:0016600)
0.1 3.3 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.3 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 1.0 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 1.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.1 GO:0097386 glial cell projection(GO:0097386)
0.0 0.7 GO:0010369 chromocenter(GO:0010369)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.5 GO:0000791 euchromatin(GO:0000791)
0.0 0.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 0.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 3.1 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.5 GO:0050436 microfibril binding(GO:0050436)
0.1 0.9 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 0.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.6 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.7 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 1.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.3 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.2 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 1.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0031696 alpha-2C adrenergic receptor binding(GO:0031696)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.2 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.5 GO:0016015 morphogen activity(GO:0016015)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.8 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0097001 glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0051800 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.2 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.1 GO:0010465 neurotrophin p75 receptor binding(GO:0005166) nerve growth factor receptor activity(GO:0010465)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0052845 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 1.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID IGF1 PATHWAY IGF1 pathway
0.0 2.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.9 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions