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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for KLF7

Z-value: 0.58

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Transcription factors associated with KLF7

Gene Symbol Gene ID Gene Info
ENSG00000118263.15 Kruppel like factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF7hg38_v1_chr2_-_207165923_207165965-0.866.2e-03Click!

Activity profile of KLF7 motif

Sorted Z-values of KLF7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_104859828 0.20 ENST00000519645.5
ENST00000262903.9
ENST00000369125.6
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr2_+_97113496 0.20 ENST00000639293.1
ENST00000461153.7
ankyrin repeat domain 36
chr17_+_19378476 0.19 ENST00000395604.8
ENST00000482850.1
mitogen-activated protein kinase 7
chr2_+_97113600 0.18 ENST00000620383.1
ankyrin repeat domain 36
chr2_-_97589711 0.16 ENST00000359901.8
ankyrin repeat domain 36B
chr1_-_161132577 0.15 ENST00000464113.1
death effector domain containing
chr2_-_187565751 0.13 ENST00000421427.5
tissue factor pathway inhibitor
chr14_-_100568070 0.13 ENST00000557378.6
ENST00000443071.6
ENST00000637646.1
brain enriched guanylate kinase associated
chr5_+_173888335 0.12 ENST00000265085.10
cytoplasmic polyadenylation element binding protein 4
chr2_-_95991793 0.11 ENST00000456556.5
ENST00000619511.1
ankyrin repeat domain 36C
chr5_+_141968886 0.11 ENST00000347642.7
ring finger protein 14
chrX_-_93673558 0.10 ENST00000475430.2
ENST00000373079.4
nucleosome assembly protein 1 like 3
chrX_+_103376488 0.10 ENST00000361298.9
brain expressed X-linked 3
chrX_+_103376389 0.10 ENST00000372645.3
ENST00000372635.1
brain expressed X-linked 3
chrX_+_103376887 0.09 ENST00000372634.1
brain expressed X-linked 3
chr12_-_49189053 0.08 ENST00000550767.6
ENST00000546918.1
ENST00000679733.1
ENST00000552924.2
ENST00000301071.12
tubulin alpha 1a
chr6_-_30617232 0.08 ENST00000376511.7
protein phosphatase 1 regulatory subunit 10
chr19_-_40425982 0.08 ENST00000357949.5
SERTA domain containing 1
chr1_-_18902520 0.08 ENST00000538839.5
ENST00000290597.9
ENST00000375341.8
aldehyde dehydrogenase 4 family member A1
chr1_-_161132659 0.07 ENST00000368006.8
ENST00000490843.6
ENST00000545495.5
death effector domain containing
chr3_-_105868964 0.07 ENST00000394030.8
Cbl proto-oncogene B
chr19_-_38899529 0.07 ENST00000249396.12
ENST00000437828.5
sirtuin 2
chr17_-_19377876 0.07 ENST00000674596.1
ENST00000642870.2
B9 domain containing 1
chr12_+_49961864 0.07 ENST00000293599.7
aquaporin 5
chr19_-_38899800 0.06 ENST00000414941.5
ENST00000358931.9
ENST00000392081.6
sirtuin 2
chr5_+_177133005 0.06 ENST00000510954.5
ENST00000354179.8
nuclear receptor binding SET domain protein 1
chr8_+_17246921 0.06 ENST00000518038.1
ENST00000324849.9
VPS37A subunit of ESCRT-I
chr2_-_97589862 0.05 ENST00000258459.11
ENST00000438709.6
ankyrin repeat domain 36B
chr8_-_17246846 0.05 ENST00000628418.1
ENST00000361272.9
ENST00000523917.5
CCR4-NOT transcription complex subunit 7
chr8_+_11284789 0.05 ENST00000221086.8
myotubularin related protein 9
chr10_-_16817362 0.05 ENST00000377921.7
ENST00000345264.10
Ras suppressor protein 1
chr15_+_92393841 0.04 ENST00000268164.8
ENST00000539113.5
ENST00000555434.1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr13_-_32538819 0.04 ENST00000674452.1
ENST00000674422.1
ENST00000674349.1
ENST00000674465.1
ENST00000674327.1
ENST00000505213.5
ENST00000357505.10
ENST00000399396.7
NEDD4 binding protein 2 like 2
chr8_+_17247030 0.04 ENST00000521829.5
ENST00000521005.1
VPS37A subunit of ESCRT-I
chr6_-_109382397 0.04 ENST00000512821.5
CD164 molecule
chr12_-_49188811 0.04 ENST00000295766.9
tubulin alpha 1a
chr2_+_69741974 0.03 ENST00000409920.5
annexin A4
chr7_+_128791390 0.03 ENST00000459946.5
ENST00000378685.8
ENST00000464832.5
ENST00000472049.1
ENST00000488925.1
coiled-coil domain containing 136
chr3_+_179148341 0.03 ENST00000263967.4
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr15_+_57706725 0.03 ENST00000380557.4
ENST00000649091.1
RNA polymerase II subunit M
chr15_+_75282835 0.02 ENST00000434739.3
golgin A6 family member D
chr12_-_6753134 0.02 ENST00000203630.10
myeloid leukemia factor 2
chr2_-_74482914 0.02 ENST00000290418.4
ENST00000393965.8
coiled-coil domain containing 142
chr17_-_42824248 0.01 ENST00000593205.5
ENST00000361523.8
ENST00000590099.6
ENST00000438274.7
beclin 1
chr1_+_27830761 0.01 ENST00000311772.10
ENST00000236412.11
ENST00000373931.8
protein phosphatase 1 regulatory subunit 8
chr12_-_46372763 0.01 ENST00000256689.10
solute carrier family 38 member 2
chr17_-_4948519 0.01 ENST00000225655.6
profilin 1
chr17_-_82098223 0.01 ENST00000306749.4
ENST00000635197.1
fatty acid synthase
chr15_+_74130243 0.00 ENST00000561740.5
ENST00000435464.5
immunoglobulin superfamily containing leucine rich repeat 2
chr8_+_89757789 0.00 ENST00000220751.5
receptor interacting serine/threonine kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0030821 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.0 0.1 GO:1900195 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0044094 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)