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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for LHX3

Z-value: 0.18

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Transcription factors associated with LHX3

Gene Symbol Gene ID Gene Info
ENSG00000107187.17 LIM homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX3hg38_v1_chr9_-_136203183_136203194,
hg38_v1_chr9_-_136205122_136205133
0.088.5e-01Click!

Activity profile of LHX3 motif

Sorted Z-values of LHX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_63608542 0.22 ENST00000540943.1
phospholipase A and acyltransferase 3
chr17_+_1771688 0.18 ENST00000572048.1
ENST00000573763.1
serpin family F member 1
chr9_+_96928310 0.17 ENST00000354649.7
NUT family member 2G
chr19_+_49513353 0.16 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr19_+_49513154 0.15 ENST00000426395.7
ENST00000600273.5
ENST00000599988.5
Fc fragment of IgG receptor and transporter
chr3_+_69763726 0.12 ENST00000448226.9
melanocyte inducing transcription factor
chr19_+_11346556 0.11 ENST00000587531.5
coiled-coil domain containing 159
chr3_-_195583931 0.10 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
apolipoprotein D
chr6_+_72216442 0.09 ENST00000425662.6
ENST00000453976.6
regulating synaptic membrane exocytosis 1
chr14_+_88385643 0.09 ENST00000393545.9
ENST00000356583.9
ENST00000555401.5
ENST00000553885.5
spermatogenesis associated 7
chr14_+_88385714 0.09 ENST00000045347.11
spermatogenesis associated 7
chr5_+_141150012 0.08 ENST00000231136.4
ENST00000622991.1
protocadherin beta 6
chr5_+_68290637 0.08 ENST00000336483.9
phosphoinositide-3-kinase regulatory subunit 1
chr19_-_48646155 0.08 ENST00000084798.9
carbonic anhydrase 11
chr1_-_48400826 0.07 ENST00000371841.1
spermatogenesis associated 6
chr4_+_186069144 0.07 ENST00000513189.1
ENST00000296795.8
toll like receptor 3
chr8_-_56211257 0.06 ENST00000316981.8
ENST00000423799.6
ENST00000429357.2
PLAG1 zinc finger
chr17_-_41467386 0.06 ENST00000225899.4
keratin 32
chr19_+_11346499 0.06 ENST00000458408.6
ENST00000586451.5
ENST00000588592.5
coiled-coil domain containing 159
chr3_-_142000353 0.06 ENST00000499676.5
transcription factor Dp-2
chr12_+_8157034 0.06 ENST00000396570.7
zinc finger protein 705A
chrX_+_109535775 0.05 ENST00000218004.5
nuclear transport factor 2 like export factor 2
chr11_+_26994102 0.05 ENST00000318627.4
fin bud initiation factor homolog
chr15_-_55408245 0.05 ENST00000563171.5
ENST00000425574.7
ENST00000442196.8
ENST00000564092.1
cell cycle progression 1
chr17_-_10469558 0.04 ENST00000255381.2
myosin heavy chain 4
chr13_-_49401497 0.04 ENST00000457041.5
ENST00000355854.8
calcium binding protein 39 like
chrX_-_107000185 0.04 ENST00000355610.9
MORC family CW-type zinc finger 4
chr10_+_87357720 0.04 ENST00000412718.3
ENST00000381697.7
NUT family member 2D
chr1_-_182671902 0.04 ENST00000483095.6
regulator of G protein signaling 8
chr10_-_27240505 0.04 ENST00000375888.5
ENST00000676732.1
acyl-CoA binding domain containing 5
chr1_-_182671853 0.04 ENST00000367556.5
regulator of G protein signaling 8
chr3_-_142029108 0.04 ENST00000497579.5
transcription factor Dp-2
chr8_+_104339796 0.04 ENST00000622554.1
ENST00000297581.2
dendrocyte expressed seven transmembrane protein
chr20_+_6007245 0.04 ENST00000378868.4
cardiolipin synthase 1
chr3_-_191282383 0.04 ENST00000427544.6
urotensin 2B
chr9_+_72577788 0.03 ENST00000645208.2
transmembrane channel like 1
chr12_+_49346911 0.03 ENST00000395069.3
DnaJ heat shock protein family (Hsp40) member C22
chr6_+_113857333 0.03 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr10_-_114144599 0.03 ENST00000428953.1
coiled-coil domain containing 186
chr3_+_151873634 0.03 ENST00000362032.6
succinate receptor 1
chr9_+_72577369 0.03 ENST00000651183.1
transmembrane channel like 1
chr3_-_165078480 0.03 ENST00000264382.8
sucrase-isomaltase
chr4_+_70592253 0.03 ENST00000322937.10
ENST00000613447.4
ameloblastin
chr19_+_14583076 0.03 ENST00000547437.5
ENST00000417570.6
C-type lectin domain containing 17A
chrX_-_13817027 0.03 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr15_-_19988117 0.03 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr9_+_122371014 0.03 ENST00000362012.7
prostaglandin-endoperoxide synthase 1
chr14_+_34993240 0.03 ENST00000677647.1
signal recognition particle 54
chr3_+_138621225 0.03 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr9_+_79573162 0.03 ENST00000425506.5
TLE family member 4, transcriptional corepressor
chr5_-_88823763 0.03 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
myocyte enhancer factor 2C
chr2_+_26401909 0.03 ENST00000288710.7
dynein regulatory complex subunit 1
chr4_+_168631597 0.03 ENST00000504519.5
ENST00000512127.5
palladin, cytoskeletal associated protein
chr18_+_74534594 0.03 ENST00000582365.1
carnosine dipeptidase 1
chr7_+_30145789 0.03 ENST00000324489.5
maturin, neural progenitor differentiation regulator homolog
chr13_-_70108441 0.02 ENST00000377844.9
ENST00000545028.2
kelch like family member 1
chr2_-_187448244 0.02 ENST00000392370.8
ENST00000410068.5
ENST00000447403.5
ENST00000410102.5
calcitonin receptor like receptor
chr18_+_616711 0.02 ENST00000579494.1
clusterin like 1
chr1_+_177170916 0.02 ENST00000361539.5
BMP/retinoic acid inducible neural specific 2
chr18_+_74534493 0.02 ENST00000358821.8
carnosine dipeptidase 1
chr3_+_138621207 0.02 ENST00000464668.5
Fas apoptotic inhibitory molecule
chr13_+_53028806 0.02 ENST00000219022.3
olfactomedin 4
chr12_-_42237727 0.02 ENST00000548917.1
YY1 associated factor 2
chr18_+_616672 0.02 ENST00000338387.11
clusterin like 1
chr9_-_21482313 0.02 ENST00000448696.4
interferon epsilon
chr20_+_45416551 0.02 ENST00000639292.1
phosphatidylinositol glycan anchor biosynthesis class T
chr2_-_2324642 0.02 ENST00000650485.1
ENST00000649207.1
myelin transcription factor 1 like
chr2_-_2324323 0.02 ENST00000648339.1
ENST00000647694.1
myelin transcription factor 1 like
chr3_+_141387801 0.02 ENST00000514251.5
zinc finger and BTB domain containing 38
chr6_+_26103922 0.02 ENST00000377803.4
H4 clustered histone 3
chr2_+_176157293 0.02 ENST00000683222.1
homeobox D3
chr11_-_117316230 0.02 ENST00000313005.11
ENST00000528053.5
beta-secretase 1
chr1_-_56819365 0.02 ENST00000343433.7
FYN binding protein 2
chr1_+_197268222 0.02 ENST00000367400.8
ENST00000638467.1
ENST00000367399.6
crumbs cell polarity complex component 1
chr18_-_24311495 0.02 ENST00000357041.8
oxysterol binding protein like 1A
chr3_+_2892199 0.02 ENST00000397459.6
contactin 4
chr17_-_69150062 0.02 ENST00000522787.5
ENST00000521538.5
ATP binding cassette subfamily A member 10
chrX_+_85003863 0.02 ENST00000373173.7
apolipoprotein O like
chr1_-_230869564 0.02 ENST00000470540.5
chromosome 1 open reading frame 198
chr17_-_44066595 0.02 ENST00000585388.2
ENST00000293406.8
LSM12 homolog
chr12_-_10130082 0.02 ENST00000533022.5
C-type lectin domain containing 7A
chr4_+_112647059 0.02 ENST00000511529.1
La ribonucleoprotein 7, transcriptional regulator
chr8_-_25424260 0.02 ENST00000421054.7
gonadotropin releasing hormone 1
chr2_-_96505345 0.02 ENST00000310865.7
ENST00000451794.6
neuralized E3 ubiquitin protein ligase 3
chr4_-_119322128 0.02 ENST00000274024.4
fatty acid binding protein 2
chr3_-_132684685 0.02 ENST00000512094.5
ENST00000632629.1
nephrocystin 3
NPHP3-ACAD11 readthrough (NMD candidate)
chr17_+_46511511 0.01 ENST00000576629.5
leucine rich repeat containing 37 member A2
chr2_-_98663464 0.01 ENST00000414521.6
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
chr8_-_30812867 0.01 ENST00000518243.5
protein phosphatase 2 catalytic subunit beta
chr7_+_138460238 0.01 ENST00000343526.9
tripartite motif containing 24
chr20_-_31475125 0.01 ENST00000317676.3
defensin beta 124
chr14_-_106593319 0.01 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr9_-_113303271 0.01 ENST00000297894.5
ENST00000489339.2
ring finger protein 183
chr18_-_24272179 0.01 ENST00000399443.7
oxysterol binding protein like 1A
chr14_+_61697622 0.01 ENST00000539097.2
hypoxia inducible factor 1 subunit alpha
chr10_+_47918659 0.01 ENST00000576178.6
ENST00000613306.1
neuropeptide Y receptor Y4-2
chr10_+_52128343 0.01 ENST00000672084.1
protein kinase cGMP-dependent 1
chr14_+_55027200 0.01 ENST00000395472.2
ENST00000555846.2
suppressor of cytokine signaling 4
chr2_+_184598520 0.01 ENST00000302277.7
zinc finger protein 804A
chr9_+_35042213 0.01 ENST00000378745.3
ENST00000312292.6
chromosome 9 open reading frame 131
chr16_+_28553908 0.01 ENST00000317058.8
SAGA complex associated factor 29
chr12_-_7503744 0.01 ENST00000396620.7
ENST00000432237.3
CD163 molecule
chr13_+_30422487 0.01 ENST00000638137.1
ENST00000635918.2
ubiquitin conjugating enzyme E2 L5
chr1_-_158426237 0.01 ENST00000641042.1
olfactory receptor family 10 subfamily K member 2
chr8_+_106726115 0.01 ENST00000521592.5
oxidation resistance 1
chr19_-_6279921 0.01 ENST00000252674.9
MLLT1 super elongation complex subunit
chr12_-_10130241 0.01 ENST00000353231.9
ENST00000525605.1
C-type lectin domain containing 7A
chr17_+_7407838 0.01 ENST00000302926.7
neuroligin 2
chr5_+_148312416 0.01 ENST00000274565.5
serine peptidase inhibitor Kazal type 7
chr12_-_10130143 0.01 ENST00000298523.9
ENST00000396484.6
ENST00000310002.4
ENST00000304084.13
C-type lectin domain containing 7A
chr2_+_134838610 0.01 ENST00000356140.10
ENST00000392928.5
aminocarboxymuconate semialdehyde decarboxylase
chr8_-_131040890 0.01 ENST00000286355.10
adenylate cyclase 8
chr19_-_51417791 0.01 ENST00000353836.9
sialic acid binding Ig like lectin 10
chr3_+_158110052 0.01 ENST00000295930.7
ENST00000471994.5
ENST00000482822.3
ENST00000476899.6
ENST00000683899.1
ENST00000684604.1
ENST00000682164.1
ENST00000464171.5
ENST00000611884.5
ENST00000312179.10
ENST00000475278.6
arginine and serine rich coiled-coil 1
chr12_-_7503841 0.01 ENST00000359156.8
CD163 molecule
chr14_+_21997531 0.01 ENST00000390445.2
T cell receptor alpha variable 17
chr14_+_55027576 0.01 ENST00000339298.2
suppressor of cytokine signaling 4
chr15_-_75455767 0.00 ENST00000360439.8
SIN3 transcription regulator family member A
chr17_-_74776323 0.00 ENST00000582870.5
ENST00000581136.5
ENST00000579218.5
ENST00000583476.5
ENST00000580301.5
ENST00000583757.5
ENST00000357814.8
ENST00000582524.5
N-acetyltransferase 9 (putative)
chr15_+_64387828 0.00 ENST00000261884.8
thyroid hormone receptor interactor 4
chr7_-_123199960 0.00 ENST00000194130.7
solute carrier family 13 member 1
chr1_+_15341744 0.00 ENST00000444385.5
forkhead associated phosphopeptide binding domain 1
chr3_-_167474026 0.00 ENST00000466903.1
ENST00000264677.8
serpin family I member 2
chr6_-_49744378 0.00 ENST00000371159.8
ENST00000263045.9
cysteine rich secretory protein 3
chr8_-_109974688 0.00 ENST00000297404.1
potassium voltage-gated channel modifier subfamily V member 1
chr9_-_125484490 0.00 ENST00000444226.1
MAPK associated protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.2 GO:0071279 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.0 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0019770 IgG receptor activity(GO:0019770)