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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for MAFF_MAFG

Z-value: 0.80

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Transcription factors associated with MAFF_MAFG

Gene Symbol Gene ID Gene Info
MAFF
ENSG00000185022.12 MAF bZIP transcription factor F
MAFG
ENSG00000197063.11 MAF bZIP transcription factor G

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAFFhg38_v1_chr22_+_38213530_38213541,
hg38_v1_chr22_+_38201932_38202014		0.866.0e-03Click!
MAFGhg38_v1_chr17_-_81923532_819235470.831.1e-02Click!

Activity profile of MAFF_MAFG motif

Sorted Z-values of MAFF_MAFG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_190122317 0.66 ENST00000427335.6
P3H2
prolyl 3-hydroxylase 2
chr12_-_84911178 0.65 ENST00000681688.1
SLC6A15
solute carrier family 6 member 15
chr19_+_35118456 0.65 ENST00000604621.5
FXYD3
FXYD domain containing ion transport regulator 3
chr16_+_4788411 0.64 ENST00000589327.5
SMIM22
small integral membrane protein 22
chr16_+_4788394 0.63 ENST00000615471.4
ENST00000589721.5
ENST00000615889.4
SMIM22
small integral membrane protein 22
chr1_-_62319264 0.60 ENST00000354381.3
KANK4
KN motif and ankyrin repeat domains 4
chr1_-_62319425 0.56 ENST00000371153.9
KANK4
KN motif and ankyrin repeat domains 4
chr1_+_89364051 0.55 ENST00000370456.5
GBP6
guanylate binding protein family member 6
chr4_-_170003738 0.55 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibril associated protein 3 like
chr1_+_153031195 0.54 ENST00000307098.5
SPRR1B
small proline rich protein 1B
chr20_+_62656359 0.54 ENST00000370507.5
SLCO4A1
solute carrier organic anion transporter family member 4A1
chr1_-_153460644 0.53 ENST00000368723.4
S100A7
S100 calcium binding protein A7
chr7_-_22194709 0.52 ENST00000458533.5
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr1_+_2073986 0.45 ENST00000461106.6
PRKCZ
protein kinase C zeta
chrX_+_139530730 0.45 ENST00000218099.7
F9
coagulation factor IX
chr1_+_2073462 0.41 ENST00000400921.6
PRKCZ
protein kinase C zeta
chr17_-_8119047 0.39 ENST00000318227.4
ALOXE3
arachidonate lipoxygenase 3
chr18_+_63775395 0.36 ENST00000398019.7
SERPINB7
serpin family B member 7
chr5_-_1886938 0.35 ENST00000613726.4
IRX4
iroquois homeobox 4
chr11_-_102798148 0.35 ENST00000315274.7
MMP1
matrix metallopeptidase 1
chr17_-_41060109 0.34 ENST00000391418.3
KRTAP2-3
keratin associated protein 2-3
chr6_-_47042306 0.34 ENST00000371253.7
ADGRF1
adhesion G protein-coupled receptor F1
chr5_+_167754918 0.34 ENST00000519204.5
TENM2
teneurin transmembrane protein 2
chr2_+_102337148 0.32 ENST00000311734.6
ENST00000409584.5
IL1RL1
interleukin 1 receptor like 1
chr2_+_197705353 0.31 ENST00000282276.8
MARS2
methionyl-tRNA synthetase 2, mitochondrial
chr2_-_31138041 0.31 ENST00000324589.9
GALNT14
polypeptide N-acetylgalactosaminyltransferase 14
chr12_+_20815672 0.31 ENST00000261196.6
ENST00000381541.7
ENST00000540229.1
SLCO1B3
SLCO1B3-SLCO1B7
solute carrier organic anion transporter family member 1B3
SLCO1B3-SLCO1B7 readthrough
chr10_-_114684612 0.29 ENST00000533213.6
ENST00000369252.8
ABLIM1
actin binding LIM protein 1
chr2_+_102008515 0.28 ENST00000441002.1
IL1R2
interleukin 1 receptor type 2
chr10_-_114684457 0.28 ENST00000392955.7
ABLIM1
actin binding LIM protein 1
chr6_-_47309898 0.26 ENST00000296861.2
TNFRSF21
TNF receptor superfamily member 21
chr11_+_60280577 0.26 ENST00000679988.1
MS4A4A
membrane spanning 4-domains A4A
chr9_-_5833014 0.26 ENST00000339450.10
ERMP1
endoplasmic reticulum metallopeptidase 1
chr9_-_137054016 0.25 ENST00000312665.7
ENST00000355097.7
ENTPD2
ectonucleoside triphosphate diphosphohydrolase 2
chr11_+_1834415 0.23 ENST00000381968.7
ENST00000381978.7
SYT8
synaptotagmin 8
chr1_+_206583255 0.23 ENST00000581888.1
RASSF5
Ras association domain family member 5
chr17_+_7440738 0.23 ENST00000575398.5
ENST00000575082.5
FGF11
fibroblast growth factor 11
chr16_+_82035245 0.23 ENST00000199936.9
HSD17B2
hydroxysteroid 17-beta dehydrogenase 2
chr11_+_60280658 0.23 ENST00000337908.5
MS4A4A
membrane spanning 4-domains A4A
chr12_-_10674013 0.23 ENST00000535345.5
ENST00000542562.5
ENST00000075503.8
STYK1
serine/threonine/tyrosine kinase 1
chr5_+_100535317 0.22 ENST00000312637.5
FAM174A
family with sequence similarity 174 member A
chr17_-_3964291 0.22 ENST00000359983.7
ENST00000352011.7
ATP2A3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr1_-_153057504 0.22 ENST00000392653.3
SPRR2A
small proline rich protein 2A
chr5_-_176630364 0.22 ENST00000310112.7
SNCB
synuclein beta
chr14_-_23155302 0.21 ENST00000529705.6
SLC7A8
solute carrier family 7 member 8
chr19_+_38930916 0.21 ENST00000308018.9
ENST00000407800.2
ENST00000402029.3
MRPS12
mitochondrial ribosomal protein S12
chr6_-_138107412 0.21 ENST00000421351.4
PERP
p53 apoptosis effector related to PMP22
chr5_-_102498913 0.21 ENST00000513675.1
ENST00000379807.7
ENST00000506729.6
SLCO6A1
solute carrier organic anion transporter family member 6A1
chr1_-_110070654 0.20 ENST00000647563.2
ALX3
ALX homeobox 3
chr2_+_119431846 0.20 ENST00000306406.5
TMEM37
transmembrane protein 37
chr5_-_176630517 0.19 ENST00000393693.7
ENST00000614675.4
SNCB
synuclein beta
chr3_+_143001562 0.19 ENST00000473835.7
ENST00000493598.6
U2SURP
U2 snRNP associated SURP domain containing
chr10_+_24208774 0.18 ENST00000376456.8
ENST00000458595.5
ENST00000376452.7
ENST00000430453.6
KIAA1217
KIAA1217
chr5_-_102499008 0.18 ENST00000389019.7
SLCO6A1
solute carrier organic anion transporter family member 6A1
chr6_+_106098933 0.18 ENST00000369089.3
PRDM1
PR/SET domain 1
chr17_+_8039034 0.18 ENST00000572022.5
ENST00000380173.6
ENST00000380183.9
ALOX15B
arachidonate 15-lipoxygenase type B
chr7_-_22500152 0.17 ENST00000406890.6
ENST00000678116.1
ENST00000424363.5
STEAP1B
STEAP family member 1B
chr18_-_55401751 0.17 ENST00000537856.7
TCF4
transcription factor 4
chr9_-_133149334 0.17 ENST00000393160.7
RALGDS
ral guanine nucleotide dissociation stimulator
chr13_+_24270681 0.17 ENST00000343003.10
ENST00000399949.6
SPATA13
spermatogenesis associated 13
chr5_-_75717368 0.16 ENST00000514838.6
ENST00000506164.5
ENST00000502826.5
ENST00000428202.7
ENST00000503835.5
POC5
POC5 centriolar protein
chr18_-_55402187 0.16 ENST00000630268.2
ENST00000570177.6
TCF4
transcription factor 4
chr10_+_24209129 0.16 ENST00000376454.8
ENST00000635504.1
KIAA1217
KIAA1217
chr10_-_14548646 0.16 ENST00000378470.5
FAM107B
family with sequence similarity 107 member B
chr17_-_8118489 0.16 ENST00000380149.6
ENST00000448843.7
ALOXE3
arachidonate lipoxygenase 3
chr6_-_89819699 0.16 ENST00000439638.1
ENST00000629399.2
ENST00000369393.8
MDN1
midasin AAA ATPase 1
chr17_-_63435184 0.16 ENST00000585153.1
CYB561
cytochrome b561
chr4_-_142305826 0.16 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr12_+_101594849 0.16 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
MYBPC1
myosin binding protein C1
chr5_+_35856883 0.16 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
IL7R
interleukin 7 receptor
chr1_+_13416351 0.15 ENST00000602960.1
PRAMEF20
PRAME family member 20
chr11_+_121590388 0.15 ENST00000527934.1
SORL1
sortilin related receptor 1
chr8_-_143568854 0.15 ENST00000524906.5
ENST00000532862.1
ENST00000534459.5
MROH6
maestro heat like repeat family member 6
chr19_+_57599874 0.15 ENST00000332854.11
ENST00000597700.6
ENST00000597864.1
ZNF530
zinc finger protein 530
chr17_-_17582417 0.15 ENST00000395783.5
PEMT
phosphatidylethanolamine N-methyltransferase
chr14_-_50944428 0.15 ENST00000532462.5
PYGL
glycogen phosphorylase L
chr17_+_50165990 0.15 ENST00000262018.8
ENST00000344627.10
ENST00000682109.1
ENST00000504073.2
SGCA
sarcoglycan alpha
chr2_+_162344108 0.14 ENST00000437150.7
ENST00000453113.6
GCA
grancalcin
chr4_-_142305935 0.14 ENST00000511838.5
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr5_+_140855882 0.14 ENST00000562220.2
ENST00000307360.6
ENST00000506939.6
PCDHA10
protocadherin alpha 10
chr8_-_144416819 0.14 ENST00000526658.1
ENST00000301305.8
SLC39A4
solute carrier family 39 member 4
chr8_-_144416481 0.14 ENST00000276833.9
SLC39A4
solute carrier family 39 member 4
chr14_-_50944475 0.14 ENST00000216392.8
ENST00000544180.6
PYGL
glycogen phosphorylase L
chr10_+_88664439 0.13 ENST00000394375.7
ENST00000608620.5
ENST00000238983.9
ENST00000355843.2
LIPF
lipase F, gastric type
chr11_+_121576760 0.13 ENST00000532694.5
ENST00000534286.5
SORL1
sortilin related receptor 1
chr2_+_162344338 0.13 ENST00000233612.8
GCA
grancalcin
chr21_+_42499600 0.13 ENST00000398341.7
SLC37A1
solute carrier family 37 member 1
chr11_+_60280531 0.13 ENST00000532114.6
MS4A4A
membrane spanning 4-domains A4A
chr2_+_191678122 0.13 ENST00000425611.9
ENST00000410026.7
NABP1
nucleic acid binding protein 1
chr3_-_151278535 0.13 ENST00000309170.8
P2RY14
purinergic receptor P2Y14
chr14_+_61187544 0.13 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
PRKCH
protein kinase C eta
chr6_+_31670379 0.13 ENST00000409525.1
LY6G5B
lymphocyte antigen 6 family member G5B
chr14_+_94174284 0.13 ENST00000304338.8
PPP4R4
protein phosphatase 4 regulatory subunit 4
chr1_-_25859352 0.13 ENST00000374298.4
ENST00000538789.5
AUNIP
aurora kinase A and ninein interacting protein
chr17_+_76384601 0.12 ENST00000592299.6
ENST00000590959.5
ENST00000323374.8
SPHK1
sphingosine kinase 1
chr9_-_34376878 0.12 ENST00000297625.8
MYORG
myogenesis regulating glycosidase (putative)
chr19_-_48513161 0.12 ENST00000673139.1
LMTK3
lemur tyrosine kinase 3
chr11_+_44726811 0.12 ENST00000533202.5
ENST00000520358.7
ENST00000533080.5
ENST00000520999.6
TSPAN18
tetraspanin 18
chr8_-_144605699 0.12 ENST00000377307.6
ENST00000276826.5
ARHGAP39
Rho GTPase activating protein 39
chr1_+_207321668 0.12 ENST00000367064.9
ENST00000314754.12
ENST00000367067.8
ENST00000644836.1
ENST00000343420.6
CD55
CD55 molecule (Cromer blood group)
chr4_+_15479204 0.12 ENST00000674945.1
ENST00000506643.5
ENST00000652443.1
ENST00000651385.1
CC2D2A
coiled-coil and C2 domain containing 2A
chr1_-_206921867 0.12 ENST00000628511.2
ENST00000367091.8
FCMR
Fc fragment of IgM receptor
chr6_-_47042260 0.12 ENST00000371243.2
ADGRF1
adhesion G protein-coupled receptor F1
chr11_+_1834804 0.12 ENST00000341958.3
SYT8
synaptotagmin 8
chr6_+_83853576 0.11 ENST00000369687.2
RIPPLY2
ripply transcriptional repressor 2
chr4_+_8182066 0.11 ENST00000508641.2
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr1_+_86547070 0.11 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr19_-_15464525 0.11 ENST00000343625.12
RASAL3
RAS protein activator like 3
chr6_-_143450662 0.11 ENST00000237283.9
ADAT2
adenosine deaminase tRNA specific 2
chr6_+_31670167 0.11 ENST00000375864.4
LY6G5B
lymphocyte antigen 6 family member G5B
chr12_-_91058016 0.11 ENST00000266719.4
KERA
keratocan
chr2_+_90038848 0.11 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr13_+_42048645 0.11 ENST00000337343.9
ENST00000261491.9
ENST00000611224.1
DGKH
diacylglycerol kinase eta
chr1_+_207321532 0.10 ENST00000367063.6
ENST00000391921.9
ENST00000645323.1
CD55
CD55 molecule (Cromer blood group)
chr2_-_74529670 0.10 ENST00000377526.4
AUP1
AUP1 lipid droplet regulating VLDL assembly factor
chr22_+_22427517 0.10 ENST00000390300.2
IGLV5-37
immunoglobulin lambda variable 5-37
chr12_-_112108743 0.10 ENST00000547133.1
ENST00000261745.9
NAA25
N-alpha-acetyltransferase 25, NatB auxiliary subunit
chr3_+_150546765 0.10 ENST00000406576.7
ENST00000460851.6
ENST00000482093.5
ENST00000273435.9
EIF2A
eukaryotic translation initiation factor 2A
chr16_-_84504612 0.10 ENST00000562447.5
ENST00000343629.11
ENST00000565765.1
MEAK7
MTOR associated protein, eak-7 homolog
chr7_-_5425404 0.10 ENST00000399434.2
TNRC18
trinucleotide repeat containing 18
chr14_+_23372809 0.10 ENST00000397242.2
ENST00000329715.2
IL25
interleukin 25
chr8_-_143939543 0.10 ENST00000345136.8
PLEC
plectin
chr11_+_34632464 0.10 ENST00000531794.5
EHF
ETS homologous factor
chr6_-_31120437 0.10 ENST00000376288.3
CDSN
corneodesmosin
chr19_-_1822038 0.10 ENST00000643515.1
REXO1
RNA exonuclease 1 homolog
chr15_-_28712323 0.10 ENST00000563027.1
GOLGA8M
golgin A8 family member M
chr16_+_30199860 0.10 ENST00000395138.6
SULT1A3
sulfotransferase family 1A member 3
chrX_-_57680260 0.10 ENST00000434992.1
NLRP2B
NLR family pyrin domain containing 2B
chr3_+_150546671 0.10 ENST00000487799.5
EIF2A
eukaryotic translation initiation factor 2A
chr19_-_14674886 0.10 ENST00000344373.8
ENST00000595472.1
ADGRE3
adhesion G protein-coupled receptor E3
chr2_-_88992903 0.10 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chr22_-_26618026 0.10 ENST00000647684.1
CRYBB1
crystallin beta B1
chr15_+_34225050 0.10 ENST00000559421.1
EMC4
ER membrane protein complex subunit 4
chr9_+_69820799 0.09 ENST00000377197.8
C9orf135
chromosome 9 open reading frame 135
chrX_-_20116871 0.09 ENST00000379651.7
ENST00000443379.7
ENST00000379643.10
MAP7D2
MAP7 domain containing 2
chr7_+_77537258 0.09 ENST00000248594.11
PTPN12
protein tyrosine phosphatase non-receptor type 12
chr1_-_204494752 0.09 ENST00000684373.1
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr2_+_181986015 0.09 ENST00000409702.1
PPP1R1C
protein phosphatase 1 regulatory inhibitor subunit 1C
chr16_-_20327801 0.09 ENST00000381360.9
GP2
glycoprotein 2
chr11_+_77128237 0.09 ENST00000409709.9
ENST00000620575.4
ENST00000458637.6
ENST00000409619.6
MYO7A
myosin VIIA
chr19_-_38930737 0.09 ENST00000430193.7
ENST00000600042.5
ENST00000221431.11
SARS2
seryl-tRNA synthetase 2, mitochondrial
chr17_-_2336435 0.09 ENST00000301364.10
ENST00000576112.2
TSR1
TSR1 ribosome maturation factor
chr12_+_57591158 0.09 ENST00000422156.7
ENST00000354947.10
ENST00000540759.6
ENST00000551772.5
ENST00000550465.5
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
chr11_-_47848467 0.09 ENST00000378460.6
NUP160
nucleoporin 160
chr15_+_23565705 0.09 ENST00000568252.1
ENST00000649065.1
MKRN3
makorin ring finger protein 3
chr11_-_85665077 0.09 ENST00000527447.2
CREBZF
CREB/ATF bZIP transcription factor
chr1_-_206921987 0.09 ENST00000530505.1
ENST00000442471.4
FCMR
Fc fragment of IgM receptor
chr11_+_75768718 0.09 ENST00000376262.7
DGAT2
diacylglycerol O-acyltransferase 2
chr8_-_61646807 0.09 ENST00000522919.5
ASPH
aspartate beta-hydroxylase
chr13_-_96053370 0.09 ENST00000376712.4
ENST00000397618.7
ENST00000376747.8
ENST00000376714.7
ENST00000638479.1
ENST00000621375.5
UGGT2
UDP-glucose glycoprotein glucosyltransferase 2
chr11_-_5227063 0.09 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
HBB
hemoglobin subunit beta
chr19_+_10625507 0.08 ENST00000590857.5
ENST00000588688.5
ENST00000586078.5
ENST00000335757.10
SLC44A2
solute carrier family 44 member 2
chr21_+_31873010 0.08 ENST00000270112.7
HUNK
hormonally up-regulated Neu-associated kinase
chr11_-_126062782 0.08 ENST00000531738.6
CDON
cell adhesion associated, oncogene regulated
chr4_-_164383986 0.08 ENST00000507270.5
ENST00000514618.5
ENST00000503008.5
MARCHF1
membrane associated ring-CH-type finger 1
chr1_-_114670018 0.08 ENST00000393274.6
ENST00000393276.7
DENND2C
DENN domain containing 2C
chr5_+_74685225 0.08 ENST00000261416.12
HEXB
hexosaminidase subunit beta
chr17_-_14236862 0.08 ENST00000420162.7
ENST00000431716.2
CDRT15
CMT1A duplicated region transcript 15
chr18_-_55589795 0.08 ENST00000568740.5
ENST00000629387.2
TCF4
transcription factor 4
chr18_-_55589836 0.08 ENST00000537578.5
ENST00000564403.6
TCF4
transcription factor 4
chr10_+_102394488 0.08 ENST00000369966.8
NFKB2
nuclear factor kappa B subunit 2
chr5_+_83077559 0.08 ENST00000511817.1
XRCC4
X-ray repair cross complementing 4
chr11_+_27055215 0.08 ENST00000525090.1
BBOX1
gamma-butyrobetaine hydroxylase 1
chr2_-_68952880 0.08 ENST00000481498.1
ENST00000328895.9
GKN2
gastrokine 2
chr1_+_179082025 0.08 ENST00000367625.8
ENST00000367627.8
ENST00000352445.10
TOR3A
torsin family 3 member A
chr1_-_39639626 0.08 ENST00000372852.4
HEYL
hes related family bHLH transcription factor with YRPW motif like
chr18_+_63907948 0.08 ENST00000238508.8
SERPINB10
serpin family B member 10
chr7_-_38249572 0.08 ENST00000436911.6
TRGC2
T cell receptor gamma constant 2
chr11_-_47848313 0.08 ENST00000530326.5
ENST00000528071.5
NUP160
nucleoporin 160
chr22_+_22409755 0.08 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr2_-_164841410 0.08 ENST00000342193.8
ENST00000375458.6
COBLL1
cordon-bleu WH2 repeat protein like 1
chr1_+_44118813 0.08 ENST00000372299.4
KLF17
Kruppel like factor 17
chr22_+_21632751 0.08 ENST00000292779.4
CCDC116
coiled-coil domain containing 116
chr3_-_119660580 0.08 ENST00000493094.6
ENST00000264231.7
ENST00000468801.1
POPDC2
popeye domain containing 2
chr15_-_58933668 0.08 ENST00000380516.7
SLTM
SAFB like transcription modulator
chr1_+_119368773 0.08 ENST00000457318.5
ENST00000622548.4
ENST00000325945.4
HAO2
hydroxyacid oxidase 2
chr11_-_28108109 0.07 ENST00000263181.7
KIF18A
kinesin family member 18A
chr11_-_63015831 0.07 ENST00000430500.6
ENST00000336232.7
SLC22A8
solute carrier family 22 member 8
chr17_-_3595831 0.07 ENST00000399759.7
TRPV1
transient receptor potential cation channel subfamily V member 1
chr15_-_66565959 0.07 ENST00000537670.5
LCTL
lactase like
chr19_-_40390175 0.07 ENST00000291823.3
HIPK4
homeodomain interacting protein kinase 4
chr1_-_155991198 0.07 ENST00000673475.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2
chr8_-_30812867 0.07 ENST00000518243.5
PPP2CB
protein phosphatase 2 catalytic subunit beta
chr3_-_57544324 0.07 ENST00000495027.5
ENST00000351747.6
ENST00000389536.8
ENST00000311202.7
DNAH12
dynein axonemal heavy chain 12
chr12_-_56636318 0.07 ENST00000549506.5
ENST00000379441.7
ENST00000551812.5
BAZ2A
bromodomain adjacent to zinc finger domain 2A
chr1_+_119368802 0.07 ENST00000361035.8
ENST00000419144.1
HAO2
HAO2-IT1
hydroxyacid oxidase 2
HAO2 intronic transcript 1
chr2_-_232776555 0.07 ENST00000438786.1
ENST00000233826.4
ENST00000409779.1
KCNJ13
potassium inwardly rectifying channel subfamily J member 13
chr2_+_85429448 0.07 ENST00000651736.1
SH2D6
SH2 domain containing 6
chr3_+_50191604 0.07 ENST00000232461.8
ENST00000433068.5
GNAT1
G protein subunit alpha transducin 1
chr2_+_231395702 0.07 ENST00000287590.6
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr1_-_228406761 0.07 ENST00000366699.3
ENST00000284551.11
TRIM11
tripartite motif containing 11
chr5_+_146447304 0.07 ENST00000296702.9
ENST00000394421.7
ENST00000679501.2
TCERG1
transcription elongation regulator 1
chr14_+_39267377 0.07 ENST00000556148.5
ENST00000348007.7
MIA2
MIA SH3 domain ER export factor 2
chr12_-_10098977 0.07 ENST00000315330.8
ENST00000457018.6
CLEC1A
C-type lectin domain family 1 member A
chr19_-_663174 0.07 ENST00000292363.10
ENST00000589762.5
RNF126
ring finger protein 126
chrX_-_31072035 0.07 ENST00000359202.5
FTHL17
ferritin heavy chain like 17
chr12_-_21941300 0.07 ENST00000684084.1
ABCC9
ATP binding cassette subfamily C member 9
chr3_-_108589375 0.07 ENST00000625495.1
ENST00000619684.4
ENST00000295746.13
CIP2A
cellular inhibitor of PP2A
chr12_-_122730828 0.07 ENST00000432564.3
HCAR1
hydroxycarboxylic acid receptor 1
chr2_-_85867641 0.07 ENST00000393808.8
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFF_MAFG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.3 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.1 0.3 GO:1902769 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.3 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.1 0.7 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.3 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.2 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.1 0.7 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.3 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.3 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 0.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.5 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.7 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.0 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.1 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.2 GO:0002934 desmosome organization(GO:0002934)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686) positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.0 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.0 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.0 0.0 GO:0097045 activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.0 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.0 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.0 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0070449 elongin complex(GO:0070449)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.6 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.1 0.7 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.3 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 0.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.3 GO:0008184 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.2 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.3 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0052852 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 1.0 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.4 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.1 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.0 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)