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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for MBD2

Z-value: 3.27

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Transcription factors associated with MBD2

Gene Symbol Gene ID Gene Info
ENSG00000134046.12 methyl-CpG binding domain protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MBD2hg38_v1_chr18_-_54224578_542246890.705.5e-02Click!

Activity profile of MBD2 motif

Sorted Z-values of MBD2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_56593685 4.74 ENST00000332822.6
noggin
chr4_+_1793285 3.42 ENST00000440486.8
ENST00000412135.7
ENST00000481110.7
ENST00000340107.8
fibroblast growth factor receptor 3
chr16_+_22814154 2.45 ENST00000261374.4
heparan sulfate-glucosamine 3-sulfotransferase 2
chr6_-_99349647 2.24 ENST00000389677.6
failed axon connections homolog, metaxin like GST domain containing
chr1_+_81800906 2.15 ENST00000674393.1
ENST00000674208.1
adhesion G protein-coupled receptor L2
chr10_-_121598359 1.97 ENST00000684153.1
fibroblast growth factor receptor 2
chr6_+_125154189 1.94 ENST00000532429.5
ENST00000534199.5
TPD52 like 1
chrX_+_153687918 1.86 ENST00000253122.10
solute carrier family 6 member 8
chr4_-_25862979 1.83 ENST00000399878.8
SEL1L family member 3
chr10_-_121598412 1.76 ENST00000360144.7
ENST00000358487.10
ENST00000369059.5
ENST00000613048.4
ENST00000356226.8
fibroblast growth factor receptor 2
chr1_+_81800368 1.60 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr6_+_89433164 1.54 ENST00000369408.9
ENST00000447838.6
ankyrin repeat domain 6
chr14_-_99272184 1.53 ENST00000357195.8
BAF chromatin remodeling complex subunit BCL11B
chr8_+_31639755 1.40 ENST00000520407.5
neuregulin 1
chr4_-_11428868 1.40 ENST00000002596.6
heparan sulfate-glucosamine 3-sulfotransferase 1
chr6_+_89433127 1.36 ENST00000339746.9
ankyrin repeat domain 6
chr19_-_19628197 1.35 ENST00000586703.1
ENST00000591042.1
ENST00000407877.8
lysophosphatidic acid receptor 2
chr14_-_99271485 1.31 ENST00000345514.2
ENST00000443726.2
BAF chromatin remodeling complex subunit BCL11B
chr12_+_52948840 1.29 ENST00000388837.6
ENST00000550600.5
keratin 18
chr10_-_121598396 1.28 ENST00000336553.10
ENST00000457416.6
fibroblast growth factor receptor 2
chr8_-_22131003 1.26 ENST00000381418.9
HR lysine demethylase and nuclear receptor corepressor
chr5_-_1886938 1.16 ENST00000613726.4
iroquois homeobox 4
chr4_+_1793776 1.12 ENST00000352904.6
fibroblast growth factor receptor 3
chr1_-_54406385 1.11 ENST00000610401.5
single stranded DNA binding protein 3
chr1_+_156282917 1.11 ENST00000295694.9
ENST00000357501.6
transmembrane protein 79
chr10_-_121598234 1.10 ENST00000369058.7
ENST00000369060.8
ENST00000359354.6
fibroblast growth factor receptor 2
chr11_-_119729158 1.08 ENST00000264025.8
nectin cell adhesion molecule 1
chr1_-_6485433 1.07 ENST00000535355.6
pleckstrin homology and RhoGEF domain containing G5
chr14_-_21098570 1.00 ENST00000360947.8
zinc finger protein 219
chr18_-_55588184 0.99 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
transcription factor 4
chr3_+_113211459 0.98 ENST00000495514.5
BOC cell adhesion associated, oncogene regulated
chr11_-_75525925 0.96 ENST00000336898.8
glycerophosphodiester phosphodiesterase domain containing 5
chr18_+_62715526 0.95 ENST00000262719.10
PH domain and leucine rich repeat protein phosphatase 1
chr3_-_185824966 0.95 ENST00000457616.6
ENST00000346192.7
insulin like growth factor 2 mRNA binding protein 2
chr3_-_185825029 0.94 ENST00000382199.7
insulin like growth factor 2 mRNA binding protein 2
chr10_-_103855406 0.93 ENST00000355946.6
ENST00000369774.8
SH3 and PX domains 2A
chr16_+_74999312 0.93 ENST00000566250.5
ENST00000567962.5
zinc and ring finger 1
chr10_-_90857680 0.91 ENST00000277874.10
ENST00000371719.2
5-hydroxytryptamine receptor 7
chr11_+_44726811 0.88 ENST00000533202.5
ENST00000520358.7
ENST00000533080.5
ENST00000520999.6
tetraspanin 18
chr8_+_31640358 0.83 ENST00000523534.5
neuregulin 1
chrX_-_153875847 0.82 ENST00000361699.8
ENST00000361981.7
L1 cell adhesion molecule
chr8_-_28386073 0.80 ENST00000523095.5
ENST00000522795.1
zinc finger protein 395
chr1_-_161038907 0.79 ENST00000318289.14
ENST00000368023.7
ENST00000423014.3
ENST00000368024.5
thiosulfate sulfurtransferase like domain containing 1
chr18_-_55588535 0.78 ENST00000566286.5
ENST00000566279.5
ENST00000626595.2
ENST00000564999.5
ENST00000616053.4
ENST00000356073.8
transcription factor 4
chr10_+_128047559 0.77 ENST00000306042.9
protein tyrosine phosphatase receptor type E
chr10_-_90857983 0.76 ENST00000336152.8
5-hydroxytryptamine receptor 7
chr6_+_43770707 0.76 ENST00000324450.11
ENST00000417285.7
ENST00000413642.8
ENST00000372055.9
ENST00000482630.7
ENST00000425836.7
ENST00000372064.9
ENST00000372077.8
ENST00000519767.5
vascular endothelial growth factor A
chr1_+_26529745 0.76 ENST00000374168.7
ENST00000374166.8
ribosomal protein S6 kinase A1
chr17_+_75525682 0.73 ENST00000392550.8
ENST00000167462.9
ENST00000375227.8
ENST00000578363.5
ENST00000579392.5
LLGL scribble cell polarity complex component 2
chr11_-_46918522 0.72 ENST00000378623.6
ENST00000534404.1
LDL receptor related protein 4
chr1_+_206507520 0.72 ENST00000579436.7
Ras association domain family member 5
chr10_-_102120246 0.71 ENST00000425280.2
LIM domain binding 1
chr9_+_22446808 0.71 ENST00000325870.3
DMRT like family A1
chr12_+_119989869 0.70 ENST00000397558.6
BICD family like cargo adaptor 1
chr12_+_19129779 0.68 ENST00000539256.5
ENST00000299275.10
ENST00000538714.5
pleckstrin homology domain containing A5
chr11_-_115504389 0.68 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
cell adhesion molecule 1
chr9_-_109498251 0.68 ENST00000374541.4
ENST00000262539.7
protein tyrosine phosphatase non-receptor type 3
chr1_+_206507546 0.67 ENST00000580449.5
ENST00000581503.6
Ras association domain family member 5
chr3_+_113211539 0.66 ENST00000682979.1
ENST00000485230.5
BOC cell adhesion associated, oncogene regulated
chr6_-_3457018 0.65 ENST00000436008.6
ENST00000406686.8
solute carrier family 22 member 23
chr6_+_167826848 0.62 ENST00000683244.1
ENST00000400825.8
afadin, adherens junction formation factor
chr8_-_141308280 0.62 ENST00000517878.6
solute carrier family 45 member 4
chr1_-_6485941 0.61 ENST00000676287.1
ENST00000400913.6
pleckstrin homology and RhoGEF domain containing G5
chr8_-_28386417 0.60 ENST00000521185.5
ENST00000520290.5
ENST00000344423.10
zinc finger protein 395
chr3_+_14947680 0.60 ENST00000435454.5
ENST00000323373.10
nuclear receptor subfamily 2 group C member 2
chr14_-_23365149 0.59 ENST00000216733.8
embryonal Fyn-associated substrate
chr19_+_35717973 0.58 ENST00000673918.1
ENST00000420124.4
lysine methyltransferase 2B
chr17_-_979726 0.57 ENST00000336868.8
nucleoredoxin
chr11_+_46332905 0.57 ENST00000343674.10
diacylglycerol kinase zeta
chr6_+_12012304 0.57 ENST00000379388.7
ENST00000627968.2
ENST00000541134.5
HIVEP zinc finger 1
chr1_-_6485895 0.56 ENST00000675694.1
pleckstrin homology and RhoGEF domain containing G5
chr14_+_70907661 0.55 ENST00000439984.7
pecanex 1
chr15_-_64775574 0.55 ENST00000300069.5
RNA binding protein, mRNA processing factor 2
chr15_+_40323683 0.55 ENST00000638170.2
InaF motif containing 2
chr19_-_40716869 0.55 ENST00000677018.1
ENST00000324464.8
ENST00000594720.6
ENST00000677496.1
coenzyme Q8B
chr13_-_75482151 0.54 ENST00000377636.8
TBC1 domain family member 4
chr13_-_75482114 0.53 ENST00000377625.6
ENST00000431480.6
TBC1 domain family member 4
chr3_-_71753582 0.53 ENST00000295612.7
eukaryotic translation initiation factor 4E family member 3
chr11_-_59615673 0.51 ENST00000263847.6
oxysterol binding protein
chr13_+_73058993 0.51 ENST00000377687.6
Kruppel like factor 5
chr10_-_124744280 0.50 ENST00000337318.8
family with sequence similarity 53 member B
chr10_-_102120318 0.50 ENST00000673968.1
LIM domain binding 1
chr20_-_52191697 0.49 ENST00000361387.6
ZFP64 zinc finger protein
chr17_-_43545707 0.49 ENST00000545089.5
ETS variant transcription factor 4
chr1_-_37808168 0.49 ENST00000373044.3
yrdC N6-threonylcarbamoyltransferase domain containing
chr17_-_43545636 0.48 ENST00000393664.6
ETS variant transcription factor 4
chr3_+_184561768 0.48 ENST00000330394.3
EPH receptor B3
chr2_-_46542555 0.48 ENST00000522587.6
ATPase H+ transporting V1 subunit E2
chr11_+_100687279 0.47 ENST00000298815.13
Rho GTPase activating protein 42
chr17_-_43545891 0.47 ENST00000591713.5
ENST00000538265.5
ETS variant transcription factor 4
chr14_-_21098848 0.46 ENST00000556174.5
ENST00000554478.5
ENST00000553980.1
ENST00000421093.6
zinc finger protein 219
chr10_+_104641282 0.46 ENST00000369701.8
sortilin related VPS10 domain containing receptor 3
chr19_-_42255119 0.46 ENST00000222329.9
ENST00000594664.1
ETS2 repressor factor
novel protein
chr22_+_37639660 0.46 ENST00000649765.2
ENST00000451997.6
SH3 domain binding protein 1
novel protein
chr4_-_1406442 0.46 ENST00000422806.2
NK1 homeobox 1
chr14_-_99604167 0.45 ENST00000380243.9
coiled-coil domain containing 85C
chr1_-_9823953 0.45 ENST00000377298.9
ENST00000361311.4
calsyntenin 1
chr19_-_17245889 0.45 ENST00000291442.4
nuclear receptor subfamily 2 group F member 6
chr7_-_519239 0.45 ENST00000354513.9
ENST00000402802.7
platelet derived growth factor subunit A
chr1_+_220528333 0.45 ENST00000677505.1
microtubule affinity regulating kinase 1
chr3_+_14947568 0.45 ENST00000413118.5
ENST00000425241.5
nuclear receptor subfamily 2 group C member 2
chr17_-_28552549 0.44 ENST00000581945.1
ENST00000444148.1
ENST00000335765.9
ENST00000301032.8
unc-119 lipid binding chaperone
chr6_+_15248855 0.44 ENST00000397311.4
jumonji and AT-rich interaction domain containing 2
chr14_+_93333210 0.44 ENST00000256339.8
unc-79 homolog, NALCN channel complex subunit
chr9_+_121651594 0.44 ENST00000408936.7
DAB2 interacting protein
chr8_-_140635617 0.43 ENST00000220592.10
argonaute RISC catalytic component 2
chr2_-_38377256 0.43 ENST00000443098.5
ENST00000449130.5
ENST00000651368.1
ENST00000378954.9
ENST00000419554.6
ENST00000451483.1
ENST00000406122.5
atlastin GTPase 2
chr3_-_128487916 0.43 ENST00000430265.6
GATA binding protein 2
chr3_-_134250831 0.43 ENST00000623711.4
receptor like tyrosine kinase
chr11_-_74731385 0.42 ENST00000622063.4
ENST00000376332.8
chordin like 2
chr12_+_132490140 0.42 ENST00000680143.1
fibrosin like 1
chr17_-_6556447 0.42 ENST00000421306.7
PITPNM family member 3
chr1_-_202958258 0.42 ENST00000367254.7
ENST00000426229.1
ENST00000340990.10
adiponectin receptor 1
chr6_-_33789090 0.42 ENST00000614475.4
ENST00000293760.10
LEM domain nuclear envelope protein 2
chr2_+_147844601 0.41 ENST00000404590.1
activin A receptor type 2A
chr16_+_57735723 0.40 ENST00000562592.5
ENST00000379661.8
ENST00000566726.5
katanin regulatory subunit B1
chr16_-_23149378 0.40 ENST00000219689.12
ubiquitin specific peptidase 31
chr17_+_29593118 0.40 ENST00000394859.8
ankyrin repeat domain 13B
chr14_+_70641896 0.39 ENST00000256367.3
tetratricopeptide repeat domain 9
chr8_-_118111806 0.39 ENST00000378204.7
exostosin glycosyltransferase 1
chr2_+_26692686 0.39 ENST00000620977.1
ENST00000302909.4
potassium two pore domain channel subfamily K member 3
chr1_-_32336224 0.39 ENST00000329421.8
MARCKS like 1
chr19_+_35000426 0.39 ENST00000411896.6
ENST00000424536.2
GRAM domain containing 1A
chr6_-_10415043 0.39 ENST00000379613.10
transcription factor AP-2 alpha
chr2_+_147845020 0.38 ENST00000241416.12
activin A receptor type 2A
chr1_-_53327883 0.38 ENST00000668071.1
ENST00000465675.6
ENST00000354412.7
ENST00000347547.7
ENST00000659993.1
ENST00000658277.1
ENST00000657895.1
ENST00000662604.1
LDL receptor related protein 8
chr19_+_35000275 0.38 ENST00000317991.10
ENST00000680623.1
GRAM domain containing 1A
chr17_-_44363839 0.38 ENST00000293443.12
family with sequence similarity 171 member A2
chr6_-_10412367 0.38 ENST00000379608.9
transcription factor AP-2 alpha
chr22_+_28883564 0.38 ENST00000544604.7
zinc and ring finger 3
chr19_-_17334844 0.37 ENST00000159087.7
anoctamin 8
chr17_-_29589536 0.37 ENST00000394869.7
GIT ArfGAP 1
chr17_-_29589606 0.37 ENST00000225394.8
GIT ArfGAP 1
chr2_+_26970628 0.37 ENST00000233121.7
ENST00000405074.7
microtubule associated protein RP/EB family member 3
chr12_-_116881431 0.37 ENST00000257572.5
harakiri, BCL2 interacting protein
chr7_+_139778229 0.36 ENST00000425687.5
ENST00000650822.1
ENST00000416849.6
ENST00000438104.6
ENST00000336425.10
thromboxane A synthase 1
chr14_-_77320855 0.36 ENST00000556394.2
ENST00000261534.9
protein O-mannosyltransferase 2
chr14_+_103385506 0.36 ENST00000303622.13
microtubule affinity regulating kinase 3
chr19_-_45973863 0.36 ENST00000263257.6
NOVA alternative splicing regulator 2
chr17_+_29593468 0.36 ENST00000614878.4
ankyrin repeat domain 13B
chr21_+_41167774 0.35 ENST00000328735.10
ENST00000347667.5
beta-secretase 2
chr14_+_103385450 0.34 ENST00000416682.6
microtubule affinity regulating kinase 3
chr20_+_56629296 0.34 ENST00000201031.3
transcription factor AP-2 gamma
chr2_+_48314637 0.34 ENST00000413569.5
ENST00000340553.8
forkhead box N2
chr12_+_50085325 0.34 ENST00000551966.5
ENST00000550477.5
ENST00000394963.9
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr16_+_74999003 0.34 ENST00000335325.9
ENST00000320619.10
zinc and ring finger 1
chr4_+_38664189 0.34 ENST00000514033.1
ENST00000261438.10
Kruppel like factor 3
chr18_+_78979811 0.34 ENST00000537592.7
spalt like transcription factor 3
chr11_+_67119245 0.33 ENST00000529006.7
ENST00000398645.6
lysine demethylase 2A
chr15_+_73684204 0.33 ENST00000537340.6
ENST00000318424.9
CD276 molecule
chr18_+_79395942 0.33 ENST00000397790.6
nuclear factor of activated T cells 1
chr3_-_48430045 0.33 ENST00000296440.11
plexin B1
chr12_+_50085194 0.33 ENST00000381513.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr17_-_6556539 0.33 ENST00000262483.13
PITPNM family member 3
chr19_+_5805018 0.33 ENST00000303212.3
neurturin
chr19_-_45645560 0.33 ENST00000587152.6
EMAP like 2
chr17_-_29622893 0.32 ENST00000345068.9
ENST00000584602.1
ENST00000388767.8
ENST00000580212.6
coronin 6
chr4_+_2059286 0.32 ENST00000423729.3
N-acetyltransferase 8 like
chrX_+_69504320 0.32 ENST00000252338.5
family with sequence similarity 155 member B
chr1_+_110339323 0.32 ENST00000602849.1
ENST00000487146.8
ENST00000618772.4
ENST00000369784.9
ENST00000650953.2
ENST00000652342.2
ENST00000654015.1
RNA binding motif protein 15
chr19_-_46746421 0.32 ENST00000263280.11
striatin 4
chr15_+_91853819 0.32 ENST00000424469.2
solute carrier organic anion transporter family member 3A1
chr18_+_8609404 0.32 ENST00000649141.2
RAB12, member RAS oncogene family
chr3_-_197297523 0.31 ENST00000434148.1
ENST00000412364.2
ENST00000661013.1
ENST00000666007.1
ENST00000422288.6
ENST00000456699.6
ENST00000392380.6
ENST00000670935.1
ENST00000656087.1
ENST00000436682.6
ENST00000662727.1
ENST00000670455.1
ENST00000659221.1
ENST00000671185.1
ENST00000669565.1
ENST00000660898.1
ENST00000667971.1
ENST00000661453.1
discs large MAGUK scaffold protein 1
chr19_+_36054879 0.31 ENST00000378860.8
ENST00000427823.3
ENST00000681542.1
ENST00000680321.1
ENST00000680359.1
ENST00000680403.1
ENST00000679714.1
ENST00000679682.1
ENST00000401500.7
ENST00000680564.1
WD repeat domain 62
chr20_-_64079906 0.31 ENST00000332298.9
regulator of G protein signaling 19
chr20_+_64080074 0.31 ENST00000336866.7
opioid related nociceptin receptor 1
chr8_+_143597814 0.30 ENST00000504548.4
tigger transposable element derived 5
chr17_-_28951443 0.30 ENST00000268756.7
ENST00000332830.9
ENST00000584685.1
PHD finger protein 12
chr9_+_100427123 0.29 ENST00000395067.7
Myb/SANT DNA binding domain containing 3
chr2_-_9555738 0.29 ENST00000310823.8
ADAM metallopeptidase domain 17
chr3_-_36945042 0.29 ENST00000645898.2
ENST00000429976.5
tetratricopeptide repeat and ankyrin repeat containing 1
chr1_+_15684284 0.29 ENST00000375799.8
ENST00000375793.2
pleckstrin homology and RUN domain containing M2
chr2_+_9951653 0.29 ENST00000324907.14
grainyhead like transcription factor 1
chr17_-_28951285 0.29 ENST00000577226.5
PHD finger protein 12
chr17_+_82519694 0.28 ENST00000335255.10
forkhead box K2
chr14_+_103385374 0.28 ENST00000678179.1
ENST00000676938.1
ENST00000678619.1
ENST00000440884.7
ENST00000560417.6
ENST00000679330.1
ENST00000556744.2
ENST00000676897.1
ENST00000677560.1
ENST00000561314.6
ENST00000677829.1
ENST00000677133.1
ENST00000676645.1
ENST00000678175.1
ENST00000429436.7
ENST00000677360.1
ENST00000678237.1
ENST00000677347.1
ENST00000677432.1
microtubule affinity regulating kinase 3
chr19_+_8209300 0.28 ENST00000558268.5
ENST00000558331.5
ceramide synthase 4
chr6_-_142945160 0.28 ENST00000367603.8
HIVEP zinc finger 2
chr13_+_98143084 0.28 ENST00000319562.11
ENST00000627049.2
FERM, ARH/RhoGEF and pleckstrin domain protein 1
chr5_-_180649579 0.28 ENST00000261937.11
ENST00000502649.5
fms related receptor tyrosine kinase 4
chr14_-_77320813 0.28 ENST00000682467.1
protein O-mannosyltransferase 2
chr22_+_48576306 0.27 ENST00000358295.9
TAFA chemokine like family member 5
chr6_-_10414985 0.27 ENST00000466073.5
ENST00000498450.3
transcription factor AP-2 alpha
chr4_+_26860809 0.27 ENST00000465503.6
ENST00000467087.7
stromal interaction molecule 2
chr8_+_30384511 0.27 ENST00000339877.8
ENST00000320203.8
ENST00000287771.9
ENST00000397323.9
RNA binding protein, mRNA processing factor
chr19_+_37907200 0.27 ENST00000222345.11
signal induced proliferation associated 1 like 3
chr1_+_179025886 0.27 ENST00000263733.5
FAM20B glycosaminoglycan xylosylkinase
chr4_+_26860778 0.27 ENST00000467011.6
stromal interaction molecule 2
chr3_-_53046031 0.26 ENST00000482396.5
ENST00000394752.8
Scm like with four mbt domains 1
chr12_+_65169546 0.26 ENST00000308330.3
LEM domain containing 3
chr6_-_142945028 0.26 ENST00000012134.7
HIVEP zinc finger 2
chr4_-_121952014 0.26 ENST00000379645.8
transient receptor potential cation channel subfamily C member 3
chr12_-_48004467 0.26 ENST00000380518.8
collagen type II alpha 1 chain
chr2_+_112275588 0.26 ENST00000409871.6
ENST00000343936.4
zinc finger CCCH-type containing 6
chr3_+_33114033 0.26 ENST00000449224.1
cartilage associated protein
chr12_-_57006476 0.25 ENST00000300101.3
zinc finger and BTB domain containing 39
chr3_+_71753834 0.25 ENST00000304411.3
G protein-coupled receptor 27
chr11_+_67266437 0.25 ENST00000308595.10
ENST00000526285.1
G protein-coupled receptor kinase 2
chr1_-_154558650 0.25 ENST00000292211.5
ubiquitin conjugating enzyme E2 Q1

Network of associatons between targets according to the STRING database.

First level regulatory network of MBD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
1.0 6.1 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.9 2.8 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.4 1.3 GO:0043000 Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.4 1.2 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.4 1.2 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.3 1.7 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.3 1.1 GO:0042335 cuticle development(GO:0042335)
0.3 1.0 GO:0003409 optic cup structural organization(GO:0003409)
0.3 0.8 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 0.7 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.2 2.9 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 4.6 GO:0035988 chondrocyte proliferation(GO:0035988)
0.2 0.9 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2 2.2 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.2 0.7 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.2 0.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 0.6 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.2 0.5 GO:2000591 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1 0.4 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 1.9 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.8 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 1.1 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.1 0.4 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.8 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 1.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.5 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 1.4 GO:0002934 desmosome organization(GO:0002934)
0.1 0.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.4 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 1.0 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1 0.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.4 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.8 GO:0042713 sperm ejaculation(GO:0042713)
0.1 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.3 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 0.7 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.5 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.7 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.8 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 0.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.2 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.5 GO:0033504 floor plate development(GO:0033504)
0.1 1.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.9 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1 0.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 1.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.7 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.6 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.3 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.3 GO:0060982 coronary artery morphogenesis(GO:0060982)
0.1 0.3 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.6 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 2.2 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 1.6 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.0 0.6 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.6 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.3 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.7 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.2 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.0 0.6 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.5 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.0 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0 1.1 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.3 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.2 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.0 0.1 GO:0021937 ventral midline development(GO:0007418) cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0022009 chronological cell aging(GO:0001300) establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0 0.1 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.0 0.5 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.2 GO:0060179 male mating behavior(GO:0060179)
0.0 0.2 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.0 0.6 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0021586 pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.4 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.3 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 1.9 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 2.9 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.2 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 1.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.4 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.7 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.8 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.0 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0090493 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 1.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.5 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.4 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.0 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.0 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 1.8 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.2 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.1 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.8 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 0.3 GO:0008623 CHRAC(GO:0008623)
0.1 2.3 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.2 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.2 GO:0098855 HCN channel complex(GO:0098855)
0.0 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 2.2 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 0.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.5 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 1.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 6.6 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.0 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.0 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.4 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.8 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.7 10.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.5 3.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 1.0 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.7 GO:0098808 mRNA cap binding(GO:0098808)
0.2 0.6 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 0.8 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 1.5 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.4 GO:0055100 adiponectin binding(GO:0055100)
0.1 1.7 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.4 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 1.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.5 GO:0001626 nociceptin receptor activity(GO:0001626)
0.1 1.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 2.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.8 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.7 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 1.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.3 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 0.4 GO:0038025 reelin receptor activity(GO:0038025)
0.1 1.0 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.2 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.1 GO:0046790 virion binding(GO:0046790)
0.1 1.9 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.1 0.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 1.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.4 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 2.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0005334 norepinephrine:sodium symporter activity(GO:0005334)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.7 GO:0034452 dynactin binding(GO:0034452)
0.0 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.4 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 4.3 GO:0019955 cytokine binding(GO:0019955)
0.0 0.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.7 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0044323 9-cis retinoic acid receptor activity(GO:0004886) retinoic acid-responsive element binding(GO:0044323) vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 1.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 7.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 1.5 GO:0035326 enhancer binding(GO:0035326)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.0 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0070546 cysteine-S-conjugate beta-lyase activity(GO:0047804) L-phenylalanine aminotransferase activity(GO:0070546)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.2 PID FGF PATHWAY FGF signaling pathway
0.1 4.5 PID BMP PATHWAY BMP receptor signaling
0.1 1.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID SHP2 PATHWAY SHP2 signaling
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.6 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 5.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 4.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.6 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation