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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for MESP1

Z-value: 0.90

Motif logo

Transcription factors associated with MESP1

Gene Symbol Gene ID Gene Info
ENSG00000166823.5 mesoderm posterior bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MESP1hg38_v1_chr15_-_89751292_89751310-0.875.5e-03Click!

Activity profile of MESP1 motif

Sorted Z-values of MESP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_59814939 1.27 ENST00000371208.5
hook microtubule tethering protein 1
chr17_-_41118369 1.27 ENST00000391413.4
keratin associated protein 4-11
chr13_-_20232303 1.04 ENST00000400065.7
ENST00000643121.1
ENST00000647029.1
ENST00000643211.1
ENST00000400066.8
ENST00000644283.1
gap junction protein beta 6
chr13_-_20232191 0.99 ENST00000647243.1
gap junction protein beta 6
chr16_+_68737284 0.98 ENST00000261769.10
ENST00000422392.6
cadherin 1
chr13_-_20192928 0.95 ENST00000382848.5
gap junction protein beta 2
chr1_-_209806124 0.89 ENST00000367021.8
ENST00000542854.5
interferon regulatory factor 6
chr17_+_9645502 0.83 ENST00000285199.12
ubiquitin specific peptidase 43
chr16_+_68645290 0.83 ENST00000264012.9
cadherin 3
chr4_+_40196907 0.81 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chr11_+_130159773 0.80 ENST00000278742.6
ST14 transmembrane serine protease matriptase
chr8_-_126557691 0.80 ENST00000652209.1
LRAT domain containing 2
chr18_-_50195138 0.79 ENST00000285039.12
myosin VB
chr1_-_12616762 0.75 ENST00000464917.5
dehydrogenase/reductase 3
chr19_+_38264563 0.73 ENST00000301244.12
ENST00000587090.5
ENST00000454580.7
serine peptidase inhibitor, Kunitz type 2
chr1_+_183186238 0.69 ENST00000493293.5
ENST00000264144.5
laminin subunit gamma 2
chr17_-_41124178 0.68 ENST00000394014.2
keratin associated protein 4-12
chr18_+_36297661 0.68 ENST00000257209.8
ENST00000590592.5
ENST00000359247.8
formin homology 2 domain containing 3
chr8_+_119208322 0.68 ENST00000614891.5
mal, T cell differentiation protein 2
chr1_+_2073986 0.68 ENST00000461106.6
protein kinase C zeta
chr11_-_108593738 0.66 ENST00000525344.5
ENST00000265843.9
exophilin 5
chr16_+_68644988 0.66 ENST00000429102.6
cadherin 3
chr19_+_35248656 0.65 ENST00000621372.4
lipolysis stimulated lipoprotein receptor
chr19_+_35248879 0.65 ENST00000347609.8
lipolysis stimulated lipoprotein receptor
chr4_+_154743993 0.65 ENST00000336356.4
lecithin retinol acyltransferase
chr7_+_26291850 0.65 ENST00000338523.9
ENST00000446848.6
sorting nexin 10
chr19_+_35248694 0.65 ENST00000361790.7
lipolysis stimulated lipoprotein receptor
chr19_+_35248728 0.65 ENST00000602003.1
ENST00000360798.7
ENST00000354900.7
lipolysis stimulated lipoprotein receptor
chr1_+_43933794 0.62 ENST00000372359.10
ENST00000498139.6
ENST00000491846.5
artemin
chr12_+_4269771 0.58 ENST00000676411.1
cyclin D2
chr3_-_111595339 0.58 ENST00000317012.5
zinc finger BED-type containing 2
chr8_+_32548303 0.57 ENST00000650967.1
neuregulin 1
chr1_-_153616289 0.57 ENST00000368701.5
ENST00000344616.4
S100 calcium binding protein A14
chr1_-_161021096 0.57 ENST00000537746.1
ENST00000368026.11
F11 receptor
chr19_+_35248375 0.55 ENST00000602122.5
lipolysis stimulated lipoprotein receptor
chr8_+_101492423 0.54 ENST00000521085.1
ENST00000646743.1
grainyhead like transcription factor 2
chr2_+_120013111 0.54 ENST00000331393.8
ENST00000443124.5
erythrocyte membrane protein band 4.1 like 5
chr4_+_40192949 0.53 ENST00000507851.5
ENST00000615577.4
ENST00000613272.4
ras homolog family member H
chr17_-_7590072 0.53 ENST00000538513.6
ENST00000570788.1
ENST00000250055.3
SRY-box transcription factor 15
chr8_+_32548210 0.53 ENST00000523079.5
ENST00000650919.1
neuregulin 1
chr9_-_123268538 0.52 ENST00000360998.3
ENST00000348403.10
spermatid perinuclear RNA binding protein
chr14_-_105168753 0.52 ENST00000331782.8
ENST00000347004.2
jagged canonical Notch ligand 2
chr1_+_109249530 0.51 ENST00000271332.4
cadherin EGF LAG seven-pass G-type receptor 2
chr18_+_49562049 0.51 ENST00000261292.9
ENST00000427224.6
ENST00000580036.5
lipase G, endothelial type
chr4_+_84583037 0.50 ENST00000295887.6
CDP-diacylglycerol synthase 1
chr12_-_52520371 0.50 ENST00000549420.1
ENST00000252242.9
ENST00000551275.1
ENST00000546577.1
keratin 5
chr7_+_16753731 0.50 ENST00000262067.5
tetraspanin 13
chr1_+_94820595 0.49 ENST00000467909.5
ENST00000422520.6
ENST00000532427.5
solute carrier family 44 member 3
chr17_-_7262343 0.49 ENST00000571881.2
ENST00000360325.11
claudin 7
chr2_+_219627394 0.48 ENST00000373760.6
solute carrier family 4 member 3
chr12_+_52949107 0.48 ENST00000388835.4
keratin 18
chr19_-_50952942 0.48 ENST00000594846.1
ENST00000336334.8
kallikrein related peptidase 5
chr1_+_94820341 0.46 ENST00000446120.6
ENST00000271227.11
ENST00000527077.5
ENST00000529450.5
solute carrier family 44 member 3
chr1_+_24319342 0.46 ENST00000361548.9
grainyhead like transcription factor 3
chr5_+_69492767 0.46 ENST00000681041.1
ENST00000680098.1
ENST00000680784.1
ENST00000396442.7
ENST00000681895.1
occludin
chr6_-_106975309 0.45 ENST00000615659.1
CD24 molecule
chr11_-_118252279 0.45 ENST00000525386.5
ENST00000527472.1
ENST00000278949.9
myelin protein zero like 3
chrX_-_153875847 0.45 ENST00000361699.8
ENST00000361981.7
L1 cell adhesion molecule
chr12_+_52948840 0.45 ENST00000388837.6
ENST00000550600.5
keratin 18
chr7_+_148339452 0.44 ENST00000463592.3
contactin associated protein 2
chr18_-_77132757 0.43 ENST00000397860.7
myelin basic protein
chr2_+_219627650 0.43 ENST00000317151.7
solute carrier family 4 member 3
chr3_+_111998739 0.43 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr3_+_113948004 0.43 ENST00000638807.2
zinc finger DHHC-type palmitoyltransferase 23
chr1_-_201399525 0.43 ENST00000367313.4
ladinin 1
chr19_+_6464229 0.42 ENST00000600229.6
ENST00000356762.7
crumbs cell polarity complex component 3
chr12_-_52949818 0.42 ENST00000546897.5
ENST00000552551.5
keratin 8
chr2_+_219627622 0.42 ENST00000358055.8
solute carrier family 4 member 3
chr9_-_133149334 0.42 ENST00000393160.7
ral guanine nucleotide dissociation stimulator
chr2_+_219627565 0.42 ENST00000273063.10
solute carrier family 4 member 3
chr18_+_31498168 0.41 ENST00000261590.13
ENST00000585206.1
ENST00000683654.1
desmoglein 2
chr17_+_57085714 0.41 ENST00000571629.5
ENST00000570423.5
ENST00000575186.5
ENST00000621116.4
ENST00000573085.1
ENST00000572814.1
A-kinase anchoring protein 1
chr4_+_74445302 0.41 ENST00000502307.1
amphiregulin
chr1_-_54801290 0.41 ENST00000371276.9
tetratricopeptide repeat domain 22
chr1_+_2050387 0.40 ENST00000378567.8
protein kinase C zeta
chr1_+_24319511 0.40 ENST00000356046.6
grainyhead like transcription factor 3
chr4_+_74445126 0.40 ENST00000395748.8
amphiregulin
chr1_-_206003442 0.40 ENST00000623893.1
RAB7B, member RAS oncogene family
chr8_+_32548267 0.40 ENST00000356819.7
neuregulin 1
chr2_-_237590660 0.40 ENST00000409576.1
RAB17, member RAS oncogene family
chr11_+_1838970 0.40 ENST00000381911.6
troponin I2, fast skeletal type
chr6_-_106974721 0.40 ENST00000606017.2
ENST00000620405.1
CD24 molecule
chr19_+_6464491 0.40 ENST00000308243.7
crumbs cell polarity complex component 3
chr1_+_101238090 0.39 ENST00000475289.2
sphingosine-1-phosphate receptor 1
chr8_-_126558461 0.39 ENST00000304916.4
LRAT domain containing 2
chr3_-_190322434 0.39 ENST00000295522.4
claudin 1
chr3_+_113947901 0.39 ENST00000330212.7
ENST00000498275.5
zinc finger DHHC-type palmitoyltransferase 23
chr17_+_57085092 0.38 ENST00000575322.1
ENST00000337714.8
A-kinase anchoring protein 1
chr6_-_136550407 0.38 ENST00000354570.8
microtubule associated protein 7
chr2_-_46462 0.37 ENST00000327669.5
family with sequence similarity 110 member C
chr20_-_23049659 0.37 ENST00000377103.3
thrombomodulin
chr19_-_50968125 0.36 ENST00000594641.1
kallikrein related peptidase 6
chr11_+_1834804 0.36 ENST00000341958.3
synaptotagmin 8
chr8_-_143572748 0.35 ENST00000529971.1
ENST00000398882.8
maestro heat like repeat family member 6
chr4_+_48016764 0.35 ENST00000295461.10
NIPA like domain containing 1
chr17_-_41140487 0.35 ENST00000345847.4
keratin associated protein 4-6
chr20_+_62642492 0.35 ENST00000217159.6
solute carrier organic anion transporter family member 4A1
chr17_-_3964291 0.35 ENST00000359983.7
ENST00000352011.7
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr19_-_19628197 0.34 ENST00000586703.1
ENST00000591042.1
ENST00000407877.8
lysophosphatidic acid receptor 2
chr15_+_40252888 0.34 ENST00000559139.5
ENST00000560669.5
ENST00000542403.3
p21 (RAC1) activated kinase 6
chr11_+_35176575 0.34 ENST00000526000.6
CD44 molecule (Indian blood group)
chr7_+_18496162 0.34 ENST00000406072.5
histone deacetylase 9
chr4_+_105895458 0.33 ENST00000379987.7
nephronectin
chr5_+_69415065 0.33 ENST00000647531.1
ENST00000645446.1
ENST00000325631.10
ENST00000454295.6
MARVEL domain containing 2
chr8_-_141308280 0.32 ENST00000517878.6
solute carrier family 45 member 4
chr2_+_68734773 0.32 ENST00000409202.8
Rho GTPase activating protein 25
chr11_+_1834415 0.32 ENST00000381968.7
ENST00000381978.7
synaptotagmin 8
chr6_+_7541612 0.31 ENST00000418664.2
desmoplakin
chr11_+_1839452 0.31 ENST00000381906.5
troponin I2, fast skeletal type
chr19_+_45340760 0.31 ENST00000585434.5
kinesin light chain 3
chr6_+_7541662 0.31 ENST00000379802.8
desmoplakin
chr5_+_69415382 0.31 ENST00000512803.5
MARVEL domain containing 2
chr2_+_172427662 0.30 ENST00000264107.12
ENST00000458358.5
integrin subunit alpha 6
chr5_-_141878396 0.30 ENST00000503492.5
ENST00000287008.8
ENST00000394536.4
protocadherin 1
chr2_-_164621461 0.30 ENST00000446413.6
ENST00000263915.8
growth factor receptor bound protein 14
chr1_-_40665654 0.30 ENST00000372684.8
regulating synaptic membrane exocytosis 3
chr14_+_75279637 0.29 ENST00000555686.1
ENST00000555672.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr2_-_237590694 0.29 ENST00000264601.8
ENST00000411462.5
ENST00000409822.1
RAB17, member RAS oncogene family
chr1_+_186828941 0.29 ENST00000367466.4
phospholipase A2 group IVA
chr11_+_1839602 0.29 ENST00000617947.4
ENST00000252898.11
troponin I2, fast skeletal type
chr1_+_13583762 0.29 ENST00000376057.8
ENST00000621990.5
ENST00000510906.5
podoplanin
chr1_+_95117324 0.29 ENST00000370203.9
ENST00000456991.5
TLC domain containing 4
chr11_-_120120880 0.29 ENST00000526881.1
tripartite motif containing 29
chr1_-_206003385 0.29 ENST00000617070.5
RAB7B, member RAS oncogene family
chr17_-_76501349 0.29 ENST00000590288.1
ENST00000313080.8
ENST00000592123.5
ENST00000591255.5
ENST00000585989.5
ENST00000675367.1
ENST00000591697.5
rhomboid 5 homolog 2
chr4_+_105895435 0.29 ENST00000453617.6
ENST00000427316.6
ENST00000514622.5
ENST00000305572.12
nephronectin
chr6_+_150683593 0.28 ENST00000644968.1
pleckstrin homology and RhoGEF domain containing G1
chr2_+_172427573 0.28 ENST00000684293.1
ENST00000409080.6
ENST00000442250.6
integrin subunit alpha 6
chr15_+_74541200 0.28 ENST00000622429.1
ENST00000346246.10
AT-rich interaction domain 3B
chr6_+_79631322 0.28 ENST00000369838.6
SH3 domain binding glutamate rich protein like 2
chr15_-_63381835 0.28 ENST00000344366.7
ENST00000178638.8
ENST00000422263.2
carbonic anhydrase 12
chr7_-_22356914 0.28 ENST00000344041.10
Rap guanine nucleotide exchange factor 5
chr17_+_39737923 0.28 ENST00000577695.5
ENST00000309156.9
growth factor receptor bound protein 7
chr7_-_138981307 0.28 ENST00000440172.5
ENST00000422774.2
KIAA1549
chr4_-_25863537 0.27 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr18_+_58221535 0.27 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr7_+_129144691 0.27 ENST00000486685.3
tetraspanin 33
chr9_-_23821809 0.27 ENST00000544538.5
ELAV like RNA binding protein 2
chr5_+_76819022 0.27 ENST00000296677.5
F2R like trypsin receptor 1
chr19_+_38789198 0.27 ENST00000314980.5
galectin 7B
chr15_+_69298896 0.27 ENST00000395407.7
ENST00000558684.5
progestin and adipoQ receptor family member 5
chr2_-_164841812 0.26 ENST00000652658.2
ENST00000444537.5
ENST00000414843.5
cordon-bleu WH2 repeat protein like 1
chr21_-_40847149 0.26 ENST00000400454.6
DS cell adhesion molecule
chr11_-_88337722 0.26 ENST00000677976.1
ENST00000528020.2
ENST00000393301.5
ENST00000529974.2
ENST00000227266.10
ENST00000678464.1
ENST00000679199.1
ENST00000527018.6
ENST00000679224.1
ENST00000678506.1
ENST00000678915.1
ENST00000524463.6
cathepsin C
chr18_+_32018817 0.26 ENST00000217740.4
ENST00000583184.1
ring finger protein 125
novel transcript
chr1_+_161706949 0.26 ENST00000350710.3
ENST00000367949.6
ENST00000367959.6
ENST00000540521.5
ENST00000546024.5
ENST00000674251.1
ENST00000674323.1
Fc receptor like A
chr11_+_44726811 0.26 ENST00000533202.5
ENST00000520358.7
ENST00000533080.5
ENST00000520999.6
tetraspanin 18
chr17_-_29176752 0.26 ENST00000533112.5
myosin XVIIIA
chr2_-_75560893 0.26 ENST00000410113.5
ENST00000393913.8
eva-1 homolog A, regulator of programmed cell death
chr22_+_39994926 0.25 ENST00000333407.11
family with sequence similarity 83 member F
chr17_-_41149823 0.25 ENST00000343246.6
keratin associated protein 4-5
chr3_+_32391694 0.25 ENST00000349718.8
CKLF like MARVEL transmembrane domain containing 7
chr11_-_115504389 0.25 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
cell adhesion molecule 1
chr17_-_41168219 0.25 ENST00000391356.4
keratin associated protein 4-3
chr1_+_161707205 0.25 ENST00000367957.7
Fc receptor like A
chr1_+_224616302 0.25 ENST00000272133.4
cornichon family AMPA receptor auxiliary protein 3
chr19_-_50969567 0.24 ENST00000310157.7
kallikrein related peptidase 6
chr11_+_45922640 0.24 ENST00000401752.6
ENST00000325468.9
LARGE xylosyl- and glucuronyltransferase 2
chr1_+_161707222 0.24 ENST00000236938.12
Fc receptor like A
chr4_-_138242325 0.24 ENST00000280612.9
solute carrier family 7 member 11
chr1_-_84997079 0.24 ENST00000284027.5
ENST00000370608.8
mucolipin TRP cation channel 2
chr20_-_52191697 0.24 ENST00000361387.6
ZFP64 zinc finger protein
chr12_+_56079843 0.24 ENST00000549282.5
ENST00000549061.5
ENST00000683059.1
erb-b2 receptor tyrosine kinase 3
chr20_+_50731571 0.24 ENST00000371610.7
par-6 family cell polarity regulator beta
chr2_-_121285194 0.24 ENST00000263707.6
transcription factor CP2 like 1
chr3_+_32391841 0.24 ENST00000334983.10
CKLF like MARVEL transmembrane domain containing 7
chr8_-_10730498 0.23 ENST00000304501.2
SRY-box transcription factor 7
chr16_-_1918407 0.23 ENST00000454677.3
heparan sulfate-glucosamine 3-sulfotransferase 6
chr19_+_7595830 0.23 ENST00000160298.9
ENST00000446248.4
calmodulin regulated spectrin associated protein family member 3
chrX_+_106726663 0.23 ENST00000255499.3
ring finger protein 128
chr15_-_44195210 0.23 ENST00000402883.5
ENST00000417257.6
FERM domain containing 5
chr14_+_75280078 0.23 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr11_+_68312542 0.23 ENST00000294304.12
LDL receptor related protein 5
chr1_+_161707244 0.23 ENST00000349527.8
ENST00000294796.8
ENST00000309691.10
ENST00000367953.7
ENST00000367950.2
Fc receptor like A
chr11_+_394196 0.22 ENST00000331563.7
ENST00000531857.1
plakophilin 3
chr5_-_74866779 0.22 ENST00000510496.5
family with sequence similarity 169 member A
chr3_+_32391871 0.22 ENST00000465248.1
CKLF like MARVEL transmembrane domain containing 7
chr7_-_44325421 0.22 ENST00000395747.6
ENST00000347193.8
ENST00000346990.8
ENST00000258682.10
ENST00000353625.8
ENST00000421607.1
ENST00000424197.5
calcium/calmodulin dependent protein kinase II beta
chrX_+_16786421 0.22 ENST00000398155.4
ENST00000380122.10
taxilin gamma
chr9_-_123184233 0.22 ENST00000447404.6
spermatid perinuclear RNA binding protein
chr17_+_75525682 0.22 ENST00000392550.8
ENST00000167462.9
ENST00000375227.8
ENST00000578363.5
ENST00000579392.5
LLGL scribble cell polarity complex component 2
chr1_-_26354080 0.21 ENST00000308182.10
crystallin beta-gamma domain containing 2
chr6_+_43771960 0.21 ENST00000230480.10
vascular endothelial growth factor A
chr17_+_82735551 0.21 ENST00000300784.8
fructosamine 3 kinase
chr3_+_50269140 0.21 ENST00000616701.5
ENST00000433753.4
ENST00000611067.4
semaphorin 3B
chr3_+_111998915 0.21 ENST00000478951.6
transgelin 3
chr19_-_43670153 0.21 ENST00000601723.5
ENST00000339082.7
ENST00000340093.8
plasminogen activator, urokinase receptor
chr19_-_38773432 0.21 ENST00000599035.1
ENST00000378626.5
galectin 7
chr22_-_37486357 0.20 ENST00000356998.8
ENST00000416983.7
ENST00000424765.2
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr6_+_41637005 0.20 ENST00000419164.6
ENST00000373051.6
MyoD family inhibitor
chr13_+_25372063 0.20 ENST00000682472.1
ATPase phospholipid transporting 8A2
chr6_-_30744537 0.20 ENST00000259874.6
ENST00000376377.2
immediate early response 3
chr17_+_75721451 0.20 ENST00000200181.8
integrin subunit beta 4
chr18_+_58045683 0.20 ENST00000592846.5
ENST00000675801.1
NEDD4 like E3 ubiquitin protein ligase
chr14_+_69879408 0.20 ENST00000361956.8
ENST00000381280.4
SPARC related modular calcium binding 1
chr2_-_159904668 0.20 ENST00000504764.5
ENST00000505052.1
ENST00000263636.5
LY75-CD302 readthrough
lymphocyte antigen 75
chr15_+_45430579 0.20 ENST00000558435.5
ENST00000344300.3
ENST00000396650.7
chromosome 15 open reading frame 48
chr10_-_117005349 0.20 ENST00000615301.4
shootin 1
chr10_-_117005173 0.20 ENST00000355371.9
shootin 1
chr19_+_45340774 0.19 ENST00000589837.5
kinesin light chain 3

Network of associatons between targets according to the STRING database.

First level regulatory network of MESP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.5 2.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.5 1.5 GO:0048817 negative regulation of transforming growth factor beta2 production(GO:0032912) negative regulation of hair follicle maturation(GO:0048817) regulation of melanosome transport(GO:1902908)
0.3 0.9 GO:0043000 Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.2 0.9 GO:0048627 myoblast development(GO:0048627)
0.2 0.7 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 0.8 GO:0032600 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.2 0.9 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.2 1.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 0.7 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.2 0.7 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.2 0.5 GO:0061573 endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650)
0.1 0.4 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.4 GO:1903348 establishment of blood-nerve barrier(GO:0008065) cellular response to lead ion(GO:0071284) positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.6 GO:2000721 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.5 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.6 GO:0061146 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.1 1.5 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.1 0.8 GO:0032439 endosome localization(GO:0032439)
0.1 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.5 GO:0048319 mesodermal cell migration(GO:0008078) axial mesoderm morphogenesis(GO:0048319)
0.1 0.8 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.3 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.8 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.4 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.2 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.3 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.5 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.5 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 2.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.3 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.2 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.8 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1 0.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.3 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) mature conventional dendritic cell differentiation(GO:0097029) positive regulation of eosinophil activation(GO:1902568)
0.1 0.8 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.4 GO:0003011 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 1.0 GO:0015871 choline transport(GO:0015871)
0.1 0.1 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 0.5 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.2 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.3 GO:0015862 uridine transport(GO:0015862)
0.1 0.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.9 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.5 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.4 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0035962 response to interleukin-13(GO:0035962)
0.0 1.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.0 0.5 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.5 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:1902081 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.2 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 2.2 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.1 GO:1902959 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.3 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.0 0.4 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:1903413 cellular response to bile acid(GO:1903413)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.1 GO:0060309 elastin catabolic process(GO:0060309)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.9 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.5 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.2 GO:0009624 response to nematode(GO:0009624)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.6 GO:0045056 transcytosis(GO:0045056)
0.0 0.2 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.0 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.6 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.6 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 1.2 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.1 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.0 0.0 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.4 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.3 GO:0039535 regulation of RIG-I signaling pathway(GO:0039535)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.0 GO:1903412 response to bile acid(GO:1903412)
0.0 1.8 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340) regulation of embryonic cell shape(GO:0016476)
0.0 0.1 GO:0001575 globoside metabolic process(GO:0001575)
0.0 1.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 1.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.3 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.0 GO:0015882 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.0 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 1.3 GO:0045576 mast cell activation(GO:0045576)
0.0 0.3 GO:0050881 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.0 0.0 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.0 0.1 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.0 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.1 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.0 GO:0051563 astrocyte activation involved in immune response(GO:0002265) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.1 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.0 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.0 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 1.9 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 0.3 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.0 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.0 GO:1904379 tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 GO:0061689 tricellular tight junction(GO:0061689)
0.2 1.2 GO:0070695 FHF complex(GO:0070695)
0.1 1.9 GO:0045179 apical cortex(GO:0045179)
0.1 3.0 GO:0005922 connexon complex(GO:0005922)
0.1 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 2.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.7 GO:0043256 laminin complex(GO:0043256)
0.1 0.2 GO:0044307 dendritic branch(GO:0044307)
0.1 4.1 GO:0045095 keratin filament(GO:0045095)
0.1 0.5 GO:0033269 internode region of axon(GO:0033269)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 1.0 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.8 GO:0016600 flotillin complex(GO:0016600)
0.0 0.9 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.2 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.8 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.7 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 1.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.0 GO:0043159 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 1.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.9 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 1.0 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.8 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.3 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.8 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 1.0 GO:0038132 neuregulin binding(GO:0038132)
0.1 1.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 1.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.6 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.1 0.2 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.1 1.0 GO:0031014 troponin T binding(GO:0031014)
0.1 0.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 1.0 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 1.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.0 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.0 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 1.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 1.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.5 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 1.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.0 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.0 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.0 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.0 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.0 GO:0008513 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.0 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.0 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 2.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 1.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 1.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides