ISMARA results: MSX2

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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for MSX2

Z-value: 0.56

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Transcription factors associated with MSX2

Gene Symbol	Gene ID	Gene Info
MSX2 Ensembl NCBI GeneCards UniProt	ENSG00000120149.9	msh homeobox 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
MSX2	hg38_v1_chr5_+_174724549_174724607	0.82	1.4e-02	Click!

Activity profile of MSX2 motif

Sorted Z-values of MSX2 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_-_137532452 Show fit	0.53	ENST00000412923.6 ENST00000511115.5 ENST00000344876.9 ENST00000507846.5 ENST00000510305.5 ENST00000611581.1	PCDH18 Ensembl NCBI GeneCards UniProt Show fit	protocadherin 18
chr6_-_166627244 Show fit	0.46	ENST00000265678.9	RPS6KA2 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A2
chr17_-_44968263 Show fit	0.34	ENST00000253407.4	C1QL1 Ensembl NCBI GeneCards UniProt Show fit	complement C1q like 1
chr16_+_53099100 Show fit	0.31	ENST00000565832.5	CHD9 Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 9
chr1_+_220879434 Show fit	0.27	ENST00000366903.8	HLX Ensembl NCBI GeneCards UniProt Show fit	H2.0 like homeobox
chr1_-_145996567 Show fit	0.23	ENST00000582401.6	TXNIP Ensembl NCBI GeneCards UniProt Show fit	thioredoxin interacting protein
chr14_-_52069039 Show fit	0.23	ENST00000216286.10	NID2 Ensembl NCBI GeneCards UniProt Show fit	nidogen 2
chr14_-_52069228 Show fit	0.23	ENST00000617139.4	NID2 Ensembl NCBI GeneCards UniProt Show fit	nidogen 2
chr7_+_134646845 Show fit	0.18	ENST00000344924.8	BPGM Ensembl NCBI GeneCards UniProt Show fit	bisphosphoglycerate mutase
chr3_-_115147237 Show fit	0.18	ENST00000357258.8	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr10_+_84194621 Show fit	0.18	ENST00000332904.7	CDHR1 Ensembl NCBI GeneCards UniProt Show fit	cadherin related family member 1
chr2_-_73233206 Show fit	0.18	ENST00000258083.3	PRADC1 Ensembl NCBI GeneCards UniProt Show fit	protease associated domain containing 1
chr3_-_115147277 Show fit	0.18	ENST00000675478.1	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr10_-_28282086 Show fit	0.17	ENST00000375719.7 ENST00000375732.5	MPP7 Ensembl NCBI GeneCards UniProt Show fit	membrane palmitoylated protein 7
chr7_+_134646798 Show fit	0.17	ENST00000418040.5 ENST00000393132.2	BPGM Ensembl NCBI GeneCards UniProt Show fit	bisphosphoglycerate mutase
chr7_+_100119607 Show fit	0.15	ENST00000262932.5	CNPY4 Ensembl NCBI GeneCards UniProt Show fit	canopy FGF signaling regulator 4
chr8_+_38974212 Show fit	0.15	ENST00000302495.5	HTRA4 Ensembl NCBI GeneCards UniProt Show fit	HtrA serine peptidase 4
chr9_+_78297143 Show fit	0.14	ENST00000347159.6	PSAT1 Ensembl NCBI GeneCards UniProt Show fit	phosphoserine aminotransferase 1
chr10_+_84194527 Show fit	0.14	ENST00000623527.4	CDHR1 Ensembl NCBI GeneCards UniProt Show fit	cadherin related family member 1
chr6_+_25652201 Show fit	0.12	ENST00000612225.4 ENST00000377961.3	SCGN Ensembl NCBI GeneCards UniProt Show fit	secretagogin, EF-hand calcium binding protein
chr12_+_119668109 Show fit	0.12	ENST00000229328.10 ENST00000630317.1	PRKAB1 Ensembl NCBI GeneCards UniProt Show fit	protein kinase AMP-activated non-catalytic subunit beta 1
chrX_+_54920796 Show fit	0.11	ENST00000442098.5 ENST00000430420.5 ENST00000453081.5 ENST00000319167.12 ENST00000622017.4 ENST00000375022.8 ENST00000399736.5 ENST00000440072.5 ENST00000173898.12 ENST00000431115.5 ENST00000440759.5 ENST00000375041.6	TRO Ensembl NCBI GeneCards UniProt Show fit	trophinin
chrX_-_49073989 Show fit	0.11	ENST00000376386.3 ENST00000553851.3	PRAF2 Ensembl NCBI GeneCards UniProt Show fit	PRA1 domain family member 2
chr11_+_33039996 Show fit	0.11	ENST00000432887.5 ENST00000528898.1 ENST00000531632.6	TCP11L1 Ensembl NCBI GeneCards UniProt Show fit	t-complex 11 like 1
chr1_-_23368301 Show fit	0.11	ENST00000374608.3	ZNF436 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 436
chr7_+_100612372 Show fit	0.11	ENST00000493970.5	MOSPD3 Ensembl NCBI GeneCards UniProt Show fit	motile sperm domain containing 3
chr15_-_37101205 Show fit	0.11	ENST00000338564.9 ENST00000558313.5 ENST00000340545.9	MEIS2 Ensembl NCBI GeneCards UniProt Show fit	Meis homeobox 2
chr7_+_100612102 Show fit	0.10	ENST00000223054.8	MOSPD3 Ensembl NCBI GeneCards UniProt Show fit	motile sperm domain containing 3
chr9_+_78297117 Show fit	0.10	ENST00000376588.4	PSAT1 Ensembl NCBI GeneCards UniProt Show fit	phosphoserine aminotransferase 1
chr14_-_50561119 Show fit	0.10	ENST00000555216.5	MAP4K5 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 5
chr11_-_125111708 Show fit	0.10	ENST00000531909.5 ENST00000529530.1	TMEM218 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 218
chr1_+_151762899 Show fit	0.10	ENST00000635322.1 ENST00000321531.10	OAZ3 Ensembl NCBI GeneCards UniProt Show fit	ornithine decarboxylase antizyme 3
chr6_+_27810041 Show fit	0.10	ENST00000369163.3	H3C10 Ensembl NCBI GeneCards UniProt Show fit	H3 clustered histone 10
chr7_+_100612430 Show fit	0.10	ENST00000379527.6	MOSPD3 Ensembl NCBI GeneCards UniProt Show fit	motile sperm domain containing 3
chr19_-_45782388 Show fit	0.10	ENST00000458663.6	DMPK Ensembl NCBI GeneCards UniProt Show fit	DM1 protein kinase
chr8_-_12755457 Show fit	0.09	ENST00000398246.8	LONRF1 Ensembl NCBI GeneCards UniProt Show fit	LON peptidase N-terminal domain and ring finger 1
chr7_+_100612522 Show fit	0.09	ENST00000393950.7 ENST00000424091.2	MOSPD3 Ensembl NCBI GeneCards UniProt Show fit	motile sperm domain containing 3
chr19_-_46634685 Show fit	0.09	ENST00000300873.4	GNG8 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit gamma 8
chr1_+_244352627 Show fit	0.08	ENST00000366537.5 ENST00000308105.5	C1orf100 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 100
chr11_+_67483019 Show fit	0.08	ENST00000279146.8 ENST00000528641.7 ENST00000682324.1 ENST00000684006.1 ENST00000683237.1 ENST00000684657.1	AIP Ensembl NCBI GeneCards UniProt Show fit	aryl hydrocarbon receptor interacting protein
chr5_+_163437569 Show fit	0.08	ENST00000512163.5 ENST00000393929.5 ENST00000510097.5 ENST00000340828.7 ENST00000511490.4 ENST00000510664.5	CCNG1 Ensembl NCBI GeneCards UniProt Show fit	cyclin G1
chr8_-_42768602 Show fit	0.07	ENST00000534622.5	CHRNA6 Ensembl NCBI GeneCards UniProt Show fit	cholinergic receptor nicotinic alpha 6 subunit
chr3_-_165078480 Show fit	0.07	ENST00000264382.8	SI Ensembl NCBI GeneCards UniProt Show fit	sucrase-isomaltase
chr12_+_54325120 Show fit	0.07	ENST00000549043.5 ENST00000552218.5 ENST00000262061.7 ENST00000553231.5 ENST00000552362.5 ENST00000455864.6 ENST00000549116.5 ENST00000551779.5	COPZ1 Ensembl NCBI GeneCards UniProt Show fit	COPI coat complex subunit zeta 1
chr19_-_45782479 Show fit	0.07	ENST00000447742.6 ENST00000354227.9 ENST00000291270.9 ENST00000683086.1 ENST00000343373.10	DMPK Ensembl NCBI GeneCards UniProt Show fit	DM1 protein kinase
chr2_-_55419821 Show fit	0.07	ENST00000644630.1 ENST00000471947.2 ENST00000436346.7 ENST00000642200.1 ENST00000413716.7 ENST00000263630.13 ENST00000645072.1	CCDC88A Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 88A
chr11_-_7941708 Show fit	0.06	ENST00000642047.1	OR10A3 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 10 subfamily A member 3
chr2_-_55419565 Show fit	0.06	ENST00000647341.1 ENST00000647401.1 ENST00000336838.10 ENST00000621814.4 ENST00000644033.1 ENST00000645477.1 ENST00000647517.1	CCDC88A Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 88A
chr14_+_64914361 Show fit	0.06	ENST00000607599.6 ENST00000548752.7 ENST00000551947.6 ENST00000549115.7 ENST00000552002.7 ENST00000551093.6 ENST00000549987.1	CHURC1 Ensembl NCBI GeneCards UniProt Show fit CHURC1-FNTB Ensembl NCBI GeneCards UniProt Show fit	churchill domain containing 1 CHURC1-FNTB readthrough
chr11_+_67483119 Show fit	0.06	ENST00000682659.1 ENST00000525341.2	AIP Ensembl NCBI GeneCards UniProt Show fit	aryl hydrocarbon receptor interacting protein
chr5_+_141417659 Show fit	0.06	ENST00000398594.4	PCDHGB7 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily B, 7
chr1_+_152970646 Show fit	0.06	ENST00000328051.3	SPRR4 Ensembl NCBI GeneCards UniProt Show fit	small proline rich protein 4
chrX_-_15314543 Show fit	0.06	ENST00000344384.8	ASB11 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and SOCS box containing 11
chr7_-_100119840 Show fit	0.06	ENST00000437822.6	TAF6 Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor 6
chr1_-_151992571 Show fit	0.06	ENST00000368809.1	S100A10 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A10
chr22_+_22588155 Show fit	0.05	ENST00000390302.3	IGLV2-33 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 2-33 (non-functional)
chrX_+_77899440 Show fit	0.05	ENST00000373335.4 ENST00000475465.1 ENST00000650309.2 ENST00000647835.1	COX7B Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit 7B
chr4_-_108762964 Show fit	0.05	ENST00000512646.5 ENST00000411864.6 ENST00000296486.8 ENST00000510706.5	ETNPPL Ensembl NCBI GeneCards UniProt Show fit	ethanolamine-phosphate phospho-lyase
chr22_-_30564889 Show fit	0.05	ENST00000401975.5 ENST00000428682.5 ENST00000423299.5	GAL3ST1 Ensembl NCBI GeneCards UniProt Show fit	galactose-3-O-sulfotransferase 1
chr11_-_13495984 Show fit	0.05	ENST00000282091.6	PTH Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone
chr8_+_9555900 Show fit	0.05	ENST00000310430.11 ENST00000520408.5 ENST00000522110.1	TNKS Ensembl NCBI GeneCards UniProt Show fit	tankyrase
chr7_+_48171451 Show fit	0.05	ENST00000435803.6	ABCA13 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily A member 13
chr1_+_202348687 Show fit	0.05	ENST00000608999.6 ENST00000391959.5 ENST00000480184.5	PPP1R12B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 12B
chr7_-_100119323 Show fit	0.04	ENST00000523306.5 ENST00000344095.8 ENST00000417349.5 ENST00000493322.5 ENST00000520135.5 ENST00000460673.2 ENST00000453269.7 ENST00000452041.5 ENST00000452438.6 ENST00000451699.5	TAF6 Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor 6
chr14_+_58298497 Show fit	0.04	ENST00000348476.7 ENST00000355431.8 ENST00000395168.7	ARID4A Ensembl NCBI GeneCards UniProt Show fit	AT-rich interaction domain 4A
chr4_+_70195719 Show fit	0.04	ENST00000683306.1	ODAM Ensembl NCBI GeneCards UniProt Show fit	odontogenic, ameloblast associated
chr1_-_153922901 Show fit	0.04	ENST00000634401.1 ENST00000368655.5	GATAD2B Ensembl NCBI GeneCards UniProt Show fit	GATA zinc finger domain containing 2B
chr10_-_45672708 Show fit	0.04	ENST00000374366.7 ENST00000374371.6 ENST00000344646.10	ZFAND4 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 4
chr9_-_4666495 Show fit	0.04	ENST00000475086.5	SPATA6L Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 6 like
chr1_-_151790475 Show fit	0.04	ENST00000368825.7 ENST00000368823.5 ENST00000368824.8 ENST00000458431.6 ENST00000368827.10 ENST00000440583.6	TDRKH Ensembl NCBI GeneCards UniProt Show fit	tudor and KH domain containing
chr7_+_8433602 Show fit	0.04	ENST00000405863.6	NXPH1 Ensembl NCBI GeneCards UniProt Show fit	neurexophilin 1
chr1_-_68232539 Show fit	0.04	ENST00000370976.7 ENST00000354777.6	WLS Ensembl NCBI GeneCards UniProt Show fit	Wnt ligand secretion mediator
chr5_+_96662214 Show fit	0.04	ENST00000395812.6	CAST Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr18_+_41955186 Show fit	0.04	ENST00000639914.1 ENST00000262039.9 ENST00000398870.7 ENST00000586545.5 ENST00000585528.5	PIK3C3 Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol 3-kinase catalytic subunit type 3
chr11_-_13496018 Show fit	0.04	ENST00000529816.1	PTH Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone
chr5_+_31532277 Show fit	0.04	ENST00000507818.6 ENST00000325366.14	C5orf22 Ensembl NCBI GeneCards UniProt Show fit	chromosome 5 open reading frame 22
chr12_-_95003666 Show fit	0.04	ENST00000327772.7 ENST00000547157.1 ENST00000684171.1 ENST00000547986.5	NDUFA12 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit A12
chr2_-_55296361 Show fit	0.04	ENST00000647547.1	CCDC88A Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 88A
chr11_-_125111579 Show fit	0.03	ENST00000532156.5 ENST00000532407.5 ENST00000279968.8 ENST00000527766.5 ENST00000529583.5 ENST00000524373.5 ENST00000527271.5 ENST00000526175.5 ENST00000529609.5 ENST00000682305.1 ENST00000533273.1	TMEM218 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 218
chr3_-_48635426 Show fit	0.03	ENST00000455886.6 ENST00000431739.5 ENST00000426599.1 ENST00000383733.7 ENST00000395550.7 ENST00000420764.6 ENST00000337000.12	SLC26A6 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 26 member 6
chr5_+_96662366 Show fit	0.03	ENST00000675179.1 ENST00000421689.6 ENST00000674984.1 ENST00000512620.5	CAST Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr9_-_134068012 Show fit	0.03	ENST00000303407.12	BRD3 Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 3
chr5_+_96662314 Show fit	0.03	ENST00000674702.1	CAST Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr2_-_27380715 Show fit	0.03	ENST00000323703.11 ENST00000436006.1	ZNF513 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 513
chr1_-_151459169 Show fit	0.03	ENST00000368863.6 ENST00000409503.5 ENST00000491586.5 ENST00000533351.5	POGZ Ensembl NCBI GeneCards UniProt Show fit	pogo transposable element derived with ZNF domain
chr1_-_151459471 Show fit	0.03	ENST00000271715.7	POGZ Ensembl NCBI GeneCards UniProt Show fit	pogo transposable element derived with ZNF domain
chr1_+_15236509 Show fit	0.03	ENST00000683790.1	FHAD1 Ensembl NCBI GeneCards UniProt Show fit	forkhead associated phosphopeptide binding domain 1
chr19_-_45584769 Show fit	0.03	ENST00000263275.5	OPA3 Ensembl NCBI GeneCards UniProt Show fit	outer mitochondrial membrane lipid metabolism regulator OPA3
chr21_-_18403754 Show fit	0.03	ENST00000284885.8	TMPRSS15 Ensembl NCBI GeneCards UniProt Show fit	transmembrane serine protease 15
chr14_-_23035223 Show fit	0.02	ENST00000425762.2	PSMB5 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 5
chr11_-_122116215 Show fit	0.02	ENST00000560104.2	BLID Ensembl NCBI GeneCards UniProt Show fit	BH3-like motif containing, cell death inducer
chr1_+_174700413 Show fit	0.02	ENST00000529145.6 ENST00000325589.9	RABGAP1L Ensembl NCBI GeneCards UniProt Show fit	RAB GTPase activating protein 1 like
chr3_+_140678041 Show fit	0.02	ENST00000286349.4	TRIM42 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 42
chr12_+_52301833 Show fit	0.02	ENST00000293525.5	KRT86 Ensembl NCBI GeneCards UniProt Show fit	keratin 86
chr17_+_44187210 Show fit	0.02	ENST00000589785.1 ENST00000592825.1 ENST00000589184.5	TMUB2 Ensembl NCBI GeneCards UniProt Show fit	transmembrane and ubiquitin like domain containing 2
chr16_+_69311339 Show fit	0.02	ENST00000254950.13	VPS4A Ensembl NCBI GeneCards UniProt Show fit	vacuolar protein sorting 4 homolog A
chr17_+_44187190 Show fit	0.02	ENST00000319511.6	TMUB2 Ensembl NCBI GeneCards UniProt Show fit	transmembrane and ubiquitin like domain containing 2
chr10_-_97445850 Show fit	0.02	ENST00000477692.6 ENST00000485122.6 ENST00000370886.9 ENST00000370885.8 ENST00000370902.8 ENST00000370884.5	EXOSC1 Ensembl NCBI GeneCards UniProt Show fit	exosome component 1
chr15_+_40953463 Show fit	0.02	ENST00000617768.5	CHAC1 Ensembl NCBI GeneCards UniProt Show fit	ChaC glutathione specific gamma-glutamylcyclotransferase 1
chr2_+_149330506 Show fit	0.02	ENST00000334166.9	LYPD6 Ensembl NCBI GeneCards UniProt Show fit	LY6/PLAUR domain containing 6
chr1_-_8817633 Show fit	0.02	ENST00000400908.7	RERE Ensembl NCBI GeneCards UniProt Show fit	arginine-glutamic acid dipeptide repeats
chr1_-_68232514 Show fit	0.02	ENST00000262348.9 ENST00000370973.2 ENST00000370971.1	WLS Ensembl NCBI GeneCards UniProt Show fit	Wnt ligand secretion mediator
chr4_+_70721953 Show fit	0.02	ENST00000381006.8 ENST00000226328.8	RUFY3 Ensembl NCBI GeneCards UniProt Show fit	RUN and FYVE domain containing 3
chr7_-_56106444 Show fit	0.02	ENST00000395422.4	CHCHD2 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil-helix-coiled-coil-helix domain containing 2
chr12_-_53336342 Show fit	0.02	ENST00000537210.2 ENST00000536324.4	SP7 Ensembl NCBI GeneCards UniProt Show fit	Sp7 transcription factor
chr6_+_159761991 Show fit	0.01	ENST00000367048.5	ACAT2 Ensembl NCBI GeneCards UniProt Show fit	acetyl-CoA acetyltransferase 2
chr3_-_142029108 Show fit	0.01	ENST00000497579.5	TFDP2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor Dp-2
chr10_-_97687191 Show fit	0.01	ENST00000370626.4	AVPI1 Ensembl NCBI GeneCards UniProt Show fit	arginine vasopressin induced 1
chr1_+_175067831 Show fit	0.01	ENST00000239462.9	TNN Ensembl NCBI GeneCards UniProt Show fit	tenascin N
chr1_-_228425350 Show fit	0.01	ENST00000366696.2	H3-4 Ensembl NCBI GeneCards UniProt Show fit	H3.4 histone
chr11_-_72112750 Show fit	0.01	ENST00000545680.5 ENST00000543587.5 ENST00000538393.5 ENST00000535234.5 ENST00000227618.8 ENST00000535503.5	ANAPC15 Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 15
chr5_+_96662046 Show fit	0.01	ENST00000338252.7 ENST00000508830.5	CAST Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr19_+_17267469 Show fit	0.01	ENST00000596335.5 ENST00000601436.5 ENST00000595632.5	BABAM1 Ensembl NCBI GeneCards UniProt Show fit	BRISC and BRCA1 A complex member 1
chr19_+_15082211 Show fit	0.01	ENST00000641398.1	OR1I1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 1 subfamily I member 1
chr10_-_103351074 Show fit	0.01	ENST00000337211.8	PCGF6 Ensembl NCBI GeneCards UniProt Show fit	polycomb group ring finger 6
chr19_+_17267376 Show fit	0.01	ENST00000447614.6 ENST00000359435.8 ENST00000599474.5 ENST00000599057.5 ENST00000598188.6 ENST00000601043.5	BABAM1 Ensembl NCBI GeneCards UniProt Show fit	BRISC and BRCA1 A complex member 1
chr17_-_10026265 Show fit	0.01	ENST00000437099.6 ENST00000396115.6	GAS7 Ensembl NCBI GeneCards UniProt Show fit	growth arrest specific 7
chr11_-_72112669 Show fit	0.01	ENST00000545944.5 ENST00000502597.2	ANAPC15 Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 15
chr11_+_17276708 Show fit	0.01	ENST00000531172.5 ENST00000529010.6 ENST00000533738.6 ENST00000323688.10	NUCB2 Ensembl NCBI GeneCards UniProt Show fit	nucleobindin 2
chr6_+_31739948 Show fit	0.01	ENST00000375755.8 ENST00000425703.5 ENST00000375750.9 ENST00000375703.7 ENST00000375740.7	MSH5 Ensembl NCBI GeneCards UniProt Show fit	mutS homolog 5
chr19_-_45584810 Show fit	0.01	ENST00000323060.3	OPA3 Ensembl NCBI GeneCards UniProt Show fit	outer mitochondrial membrane lipid metabolism regulator OPA3
chr16_+_69424634 Show fit	0.01	ENST00000515314.6 ENST00000561792.6 ENST00000568237.1	CYB5B Ensembl NCBI GeneCards UniProt Show fit	cytochrome b5 type B
chr4_-_145180496 Show fit	0.01	ENST00000447906.8	OTUD4 Ensembl NCBI GeneCards UniProt Show fit	OTU deubiquitinase 4
chr7_+_100586304 Show fit	0.01	ENST00000241071.11	FBXO24 Ensembl NCBI GeneCards UniProt Show fit	F-box protein 24
chr3_-_180679468 Show fit	0.01	ENST00000651046.1 ENST00000476379.6	CCDC39 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 39
chrX_-_21658324 Show fit	0.01	ENST00000379499.3	KLHL34 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 34
chr10_-_54801262 Show fit	0.01	ENST00000373965.6 ENST00000616114.4 ENST00000621708.4 ENST00000495484.5 ENST00000395440.5 ENST00000395442.5 ENST00000617271.4 ENST00000395446.5 ENST00000409834.5 ENST00000361849.7 ENST00000373957.7 ENST00000395430.5 ENST00000395433.5 ENST00000437009.5	PCDH15 Ensembl NCBI GeneCards UniProt Show fit	protocadherin related 15
chr19_+_41363989 Show fit	0.01	ENST00000413014.6	TMEM91 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 91
chr10_-_54801221 Show fit	0.01	ENST00000644397.2 ENST00000395445.6 ENST00000613657.5 ENST00000320301.11	PCDH15 Ensembl NCBI GeneCards UniProt Show fit	protocadherin related 15
chr7_-_88795732 Show fit	0.01	ENST00000297203.3	TEX47 Ensembl NCBI GeneCards UniProt Show fit	testis expressed 47
chr6_+_106360668 Show fit	0.01	ENST00000633556.3	CRYBG1 Ensembl NCBI GeneCards UniProt Show fit	crystallin beta-gamma domain containing 1
chr2_+_113072318 Show fit	0.00	ENST00000393197.3	IL1F10 Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 family member 10
chr17_-_10469558 Show fit	0.00	ENST00000255381.2	MYH4 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 4
chr10_-_103351133 Show fit	0.00	ENST00000369847.4	PCGF6 Ensembl NCBI GeneCards UniProt Show fit	polycomb group ring finger 6
chr3_-_120285215 Show fit	0.00	ENST00000464295.6	GPR156 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 156
chr11_-_72112068 Show fit	0.00	ENST00000537644.5 ENST00000538919.5 ENST00000539395.1 ENST00000542531.5	ANAPC15 Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 15
chr6_-_116545658 Show fit	0.00	ENST00000368602.4	TRAPPC3L Ensembl NCBI GeneCards UniProt Show fit	trafficking protein particle complex 3 like
chr10_-_54801179 Show fit	0.00	ENST00000373955.5	PCDH15 Ensembl NCBI GeneCards UniProt Show fit	protocadherin related 15

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0099558	maintenance of synapse structure(GO:0099558)
0.1	0.2	GO:0042819	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
0.1	0.4	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	0.3	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.1	GO:0015847	putrescine transport(GO:0015847)
0.0	0.2	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.0	0.2	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.1	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
0.0	0.0	GO:0034183	negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.0	0.1	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.0	0.1	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.0	GO:0042938	dipeptide transport(GO:0042938)
0.0	0.2	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.1	GO:0019236	response to pheromone(GO:0019236)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0044245	polysaccharide digestion(GO:0044245)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.2	GO:0044301	climbing fiber(GO:0044301)
0.1	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.1	GO:0005965	protein farnesyltransferase complex(GO:0005965)
0.3	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.1	GO:0015489	polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.0	0.1	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0004660	protein farnesyltransferase activity(GO:0004660)
0.0	0.1	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.0	0.1	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome

Results for MSX2

Z-value: 0.56

Motif logo

Transcription factors associated with MSX2

Activity-expression correlation:

Activity profile of MSX2 motif

Sorted Z-values of MSX2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: