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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NFATC2_NFATC3

Z-value: 0.71

Motif logo

Transcription factors associated with NFATC2_NFATC3

Gene Symbol Gene ID Gene Info
ENSG00000101096.20 nuclear factor of activated T cells 2
ENSG00000072736.19 nuclear factor of activated T cells 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC2hg38_v1_chr20_-_51562829_51562853-0.705.1e-02Click!
NFATC3hg38_v1_chr16_+_68085861_680859680.344.1e-01Click!

Activity profile of NFATC2_NFATC3 motif

Sorted Z-values of NFATC2_NFATC3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_31447732 1.09 ENST00000257189.5
desmoglein 3
chr20_+_59604527 0.66 ENST00000371015.6
phosphatase and actin regulator 3
chr7_-_41703062 0.63 ENST00000242208.5
inhibin subunit beta A
chr5_+_140875299 0.58 ENST00000613593.1
ENST00000398631.3
protocadherin alpha 12
chr6_-_136466858 0.54 ENST00000544465.5
microtubule associated protein 7
chr10_-_114684612 0.53 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr1_+_43935807 0.51 ENST00000438616.3
artemin
chr5_+_140841183 0.50 ENST00000378123.4
ENST00000531613.2
protocadherin alpha 8
chr5_+_140827950 0.49 ENST00000378126.4
ENST00000529310.6
ENST00000527624.1
protocadherin alpha 6
chr5_+_140848360 0.48 ENST00000532602.2
protocadherin alpha 9
chr1_+_46175079 0.46 ENST00000372003.6
tetraspanin 1
chr2_-_215138603 0.44 ENST00000272895.12
ATP binding cassette subfamily A member 12
chr18_-_49849827 0.41 ENST00000592688.1
myosin VB
chr1_+_81800906 0.41 ENST00000674393.1
ENST00000674208.1
adhesion G protein-coupled receptor L2
chr3_-_56775657 0.40 ENST00000413728.6
Rho guanine nucleotide exchange factor 3
chr5_+_140882116 0.40 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
protocadherin alpha 13
chrX_+_106693838 0.39 ENST00000324342.7
ring finger protein 128
chr5_+_140806929 0.39 ENST00000378125.4
ENST00000618834.1
ENST00000530339.2
ENST00000512229.6
ENST00000672575.1
protocadherin alpha 4
chr5_+_66828762 0.38 ENST00000490016.6
ENST00000403666.5
ENST00000450827.5
microtubule associated serine/threonine kinase family member 4
chr8_-_126557691 0.38 ENST00000652209.1
LRAT domain containing 2
chrX_-_15664798 0.38 ENST00000380342.4
collectrin, amino acid transport regulator
chr18_-_26549402 0.38 ENST00000408011.7
potassium channel tetramerization domain containing 1
chr14_-_23154422 0.38 ENST00000422941.6
solute carrier family 7 member 8
chr5_+_140868945 0.37 ENST00000398640.7
protocadherin alpha 11
chr11_-_72781858 0.37 ENST00000537947.5
StAR related lipid transfer domain containing 10
chr12_+_82686889 0.37 ENST00000321196.8
transmembrane O-mannosyltransferase targeting cadherins 2
chr10_+_46375619 0.37 ENST00000584982.7
ENST00000613703.4
annexin A8 like 1
chr11_-_72781833 0.35 ENST00000535054.1
ENST00000545082.5
StAR related lipid transfer domain containing 10
chr14_+_64704380 0.34 ENST00000247226.13
ENST00000394691.7
pleckstrin homology and RhoGEF domain containing G3
chr18_+_63775395 0.32 ENST00000398019.7
serpin family B member 7
chr6_+_106086316 0.31 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr20_+_46008900 0.31 ENST00000372330.3
matrix metallopeptidase 9
chr18_-_26657401 0.31 ENST00000580191.5
potassium channel tetramerization domain containing 1
chr5_+_168291599 0.31 ENST00000265293.9
WW and C2 domain containing 1
chr11_+_128693887 0.31 ENST00000281428.12
Fli-1 proto-oncogene, ETS transcription factor
chr6_+_106098933 0.30 ENST00000369089.3
PR/SET domain 1
chr8_-_94262308 0.29 ENST00000297596.3
ENST00000396194.6
GTP binding protein overexpressed in skeletal muscle
chr6_+_150143018 0.28 ENST00000361131.5
protein phosphatase 1 regulatory inhibitor subunit 14C
chr12_-_50222348 0.28 ENST00000552823.5
ENST00000552909.5
LIM domain and actin binding 1
chr10_+_46375645 0.28 ENST00000622769.4
annexin A8 like 1
chr10_-_114684457 0.27 ENST00000392955.7
actin binding LIM protein 1
chr6_+_15246054 0.27 ENST00000341776.7
jumonji and AT-rich interaction domain containing 2
chr1_+_43933277 0.26 ENST00000414809.7
artemin
chr8_-_15238423 0.26 ENST00000382080.6
sarcoglycan zeta
chr5_+_140834230 0.26 ENST00000356878.5
ENST00000525929.2
protocadherin alpha 7
chr6_+_106087580 0.26 ENST00000424894.1
ENST00000648754.1
PR/SET domain 1
chr13_-_40666600 0.26 ENST00000379561.6
forkhead box O1
chr2_+_197705353 0.26 ENST00000282276.8
methionyl-tRNA synthetase 2, mitochondrial
chr17_-_58415628 0.25 ENST00000583753.5
ring finger protein 43
chr1_-_207032749 0.24 ENST00000359470.6
ENST00000461135.2
chromosome 1 open reading frame 116
chr12_-_52434363 0.24 ENST00000252245.6
keratin 75
chr12_-_6375556 0.24 ENST00000228916.7
sodium channel epithelial 1 subunit alpha
chr19_-_55370455 0.24 ENST00000264563.7
ENST00000585513.1
ENST00000590625.5
interleukin 11
chr15_+_43593054 0.23 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
creatine kinase, mitochondrial 1B
chr2_-_112836702 0.23 ENST00000416750.1
ENST00000263341.7
ENST00000418817.5
interleukin 1 beta
chr14_-_23154369 0.23 ENST00000453702.5
solute carrier family 7 member 8
chr4_+_99816797 0.23 ENST00000512369.2
ENST00000296414.11
dual adaptor of phosphotyrosine and 3-phosphoinositides 1
chr7_+_26291850 0.23 ENST00000338523.9
ENST00000446848.6
sorting nexin 10
chr5_-_79512794 0.22 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
homer scaffold protein 1
chr8_+_97887903 0.22 ENST00000520016.5
matrilin 2
chr4_-_70666492 0.22 ENST00000254801.9
ENST00000391614.7
joining chain of multimeric IgA and IgM
chr8_-_28386417 0.22 ENST00000521185.5
ENST00000520290.5
ENST00000344423.10
zinc finger protein 395
chr8_-_28386073 0.21 ENST00000523095.5
ENST00000522795.1
zinc finger protein 395
chr13_+_79481468 0.20 ENST00000620924.1
Nedd4 family interacting protein 2
chr6_-_136550819 0.20 ENST00000616617.4
ENST00000618822.4
microtubule associated protein 7
chr5_+_140821598 0.20 ENST00000614258.1
ENST00000529859.2
ENST00000529619.5
protocadherin alpha 5
chr8_+_127736220 0.20 ENST00000524013.2
ENST00000621592.8
MYC proto-oncogene, bHLH transcription factor
chr15_+_45430579 0.20 ENST00000558435.5
ENST00000344300.3
ENST00000396650.7
chromosome 15 open reading frame 48
chr5_+_140786291 0.19 ENST00000394633.7
protocadherin alpha 1
chr7_-_157010615 0.19 ENST00000252971.11
motor neuron and pancreas homeobox 1
chr1_-_161021096 0.19 ENST00000537746.1
ENST00000368026.11
F11 receptor
chr1_-_205994439 0.19 ENST00000617991.4
RAB7B, member RAS oncogene family
chr9_-_123184233 0.19 ENST00000447404.6
spermatid perinuclear RNA binding protein
chr18_+_22169580 0.18 ENST00000269216.10
GATA binding protein 6
chr6_-_11779606 0.18 ENST00000506810.1
androgen dependent TFPI regulating protein
chr13_-_85799400 0.17 ENST00000647374.2
SLIT and NTRK like family member 6
chr5_+_140801028 0.17 ENST00000532566.3
ENST00000522353.3
protocadherin alpha 3
chr3_-_142029108 0.17 ENST00000497579.5
transcription factor Dp-2
chr1_+_81800368 0.17 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr10_+_110207587 0.17 ENST00000332674.9
ENST00000453116.5
MAX interactor 1, dimerization protein
chr12_-_85836372 0.16 ENST00000361228.5
Ras association domain family member 9
chrX_-_134658450 0.16 ENST00000359237.9
placenta enriched 1
chr3_+_111999326 0.16 ENST00000494932.1
transgelin 3
chr6_-_170291053 0.16 ENST00000366756.4
delta like canonical Notch ligand 1
chr2_-_74440484 0.16 ENST00000305557.9
ENST00000233330.6
rhotekin
chr4_-_99435134 0.16 ENST00000476959.5
ENST00000482593.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_+_156147350 0.16 ENST00000435124.5
ENST00000633494.1
semaphorin 4A
chr18_-_55422306 0.16 ENST00000566777.5
ENST00000626584.2
transcription factor 4
chr7_-_20217342 0.16 ENST00000400331.10
ENST00000332878.8
MET transcriptional regulator MACC1
chr6_-_47042306 0.15 ENST00000371253.7
adhesion G protein-coupled receptor F1
chr20_-_14337602 0.15 ENST00000378053.3
ENST00000341420.5
fibronectin leucine rich transmembrane protein 3
chr4_+_70334963 0.15 ENST00000273936.6
calcium binding protein, spermatid associated 1
chr18_-_55422492 0.15 ENST00000561992.5
ENST00000630712.2
transcription factor 4
chr4_-_71784046 0.15 ENST00000513476.5
ENST00000273951.13
GC vitamin D binding protein
chr1_+_161721563 0.15 ENST00000367948.6
Fc receptor like B
chr17_+_76376581 0.15 ENST00000591651.5
ENST00000545180.5
sphingosine kinase 1
chr15_-_52295792 0.14 ENST00000261839.12
myosin VC
chr11_+_34632464 0.14 ENST00000531794.5
ETS homologous factor
chr5_+_136059151 0.14 ENST00000503087.1
transforming growth factor beta induced
chr12_+_34022462 0.14 ENST00000538927.1
ENST00000266483.7
ALG10 alpha-1,2-glucosyltransferase
chr13_+_79481446 0.14 ENST00000487865.5
Nedd4 family interacting protein 2
chr8_-_17697654 0.13 ENST00000297488.10
microtubule associated scaffold protein 1
chr1_-_183590439 0.13 ENST00000367535.8
neutrophil cytosolic factor 2
chr12_-_70637405 0.13 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
protein tyrosine phosphatase receptor type B
chr2_+_86441341 0.13 ENST00000312912.10
ENST00000409064.5
lysine demethylase 3A
chr3_+_14402592 0.13 ENST00000622186.5
ENST00000621751.4
solute carrier family 6 member 6
chr19_+_40775511 0.13 ENST00000263369.4
ENST00000597140.5
MIA SH3 domain containing
chr1_+_24319511 0.13 ENST00000356046.6
grainyhead like transcription factor 3
chr3_+_141262614 0.13 ENST00000504264.5
2-phosphoxylose phosphatase 1
chr18_+_58221535 0.13 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr12_-_54385727 0.13 ENST00000551109.5
ENST00000546970.5
zinc finger protein 385A
chr20_+_56629296 0.13 ENST00000201031.3
transcription factor AP-2 gamma
chr2_+_232697362 0.12 ENST00000482666.5
ENST00000483164.5
ENST00000490229.5
ENST00000464805.5
ENST00000489328.1
GRB10 interacting GYF protein 2
chr6_-_47042260 0.12 ENST00000371243.2
adhesion G protein-coupled receptor F1
chr12_-_23951020 0.12 ENST00000441133.2
ENST00000545921.5
SRY-box transcription factor 5
chr3_-_125120813 0.12 ENST00000430155.6
solute carrier family 12 member 8
chr1_-_156705742 0.12 ENST00000368221.1
cellular retinoic acid binding protein 2
chr1_-_156705764 0.12 ENST00000621784.4
ENST00000368220.1
cellular retinoic acid binding protein 2
chr1_+_153776596 0.12 ENST00000458027.5
solute carrier family 27 member 3
chr1_-_153565535 0.12 ENST00000368707.5
S100 calcium binding protein A2
chr17_+_40177460 0.12 ENST00000620260.6
Rap guanine nucleotide exchange factor like 1
chr9_+_113150991 0.12 ENST00000259392.8
solute carrier family 31 member 2
chrX_-_117973579 0.11 ENST00000371878.5
kelch like family member 13
chr5_-_78549151 0.11 ENST00000515007.6
LHFPL tetraspan subfamily member 2
chr1_+_101238090 0.11 ENST00000475289.2
sphingosine-1-phosphate receptor 1
chr1_+_213989691 0.11 ENST00000607425.1
prospero homeobox 1
chr9_+_100442271 0.11 ENST00000502978.1
MSANTD3-TMEFF1 readthrough
chr17_+_32487686 0.11 ENST00000584792.5
cyclin dependent kinase 5 regulatory subunit 1
chr18_-_55403682 0.11 ENST00000564228.5
ENST00000630828.2
transcription factor 4
chr13_+_97222296 0.11 ENST00000343600.8
ENST00000376673.7
ENST00000679496.1
ENST00000345429.10
muscleblind like splicing regulator 2
chr17_-_48610971 0.11 ENST00000239165.9
homeobox B7
chr14_+_75069577 0.11 ENST00000238686.8
zinc finger C2HC-type containing 1C
chr5_+_136058849 0.11 ENST00000508076.5
transforming growth factor beta induced
chr1_+_24319342 0.11 ENST00000361548.9
grainyhead like transcription factor 3
chrX_-_117973717 0.11 ENST00000262820.7
kelch like family member 13
chr1_-_183590596 0.11 ENST00000418089.5
ENST00000413720.5
neutrophil cytosolic factor 2
chr19_+_40775154 0.11 ENST00000594436.5
ENST00000597784.5
MIA SH3 domain containing
chrY_-_2787676 0.11 ENST00000383070.2
sex determining region Y
chr4_-_99435336 0.11 ENST00000437033.7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr13_-_99016034 0.10 ENST00000448493.7
dedicator of cytokinesis 9
chr1_-_156705575 0.10 ENST00000368222.8
cellular retinoic acid binding protein 2
chr10_+_116545907 0.10 ENST00000369221.2
pancreatic lipase
chr12_+_4269771 0.10 ENST00000676411.1
cyclin D2
chr1_+_247416149 0.10 ENST00000366497.6
ENST00000391828.8
NLR family pyrin domain containing 3
chr4_+_68447453 0.10 ENST00000305363.9
transmembrane serine protease 11E
chr17_+_36103819 0.10 ENST00000615863.2
ENST00000621626.1
C-C motif chemokine ligand 4
chr8_-_94436926 0.10 ENST00000481490.3
fibrinogen silencer binding protein
chr3_+_14402576 0.10 ENST00000613060.4
solute carrier family 6 member 6
chr12_+_38316753 0.10 ENST00000551464.1
ENST00000308742.9
ALG10 alpha-1,2-glucosyltransferase B
chr2_+_102355750 0.10 ENST00000233957.7
interleukin 18 receptor 1
chr10_+_119207560 0.10 ENST00000392870.3
G protein-coupled receptor kinase 5
chr18_-_70205655 0.10 ENST00000255674.11
ENST00000640769.2
rotatin
chr1_+_247416166 0.10 ENST00000391827.3
ENST00000336119.8
NLR family pyrin domain containing 3
chr7_+_148339452 0.10 ENST00000463592.3
contactin associated protein 2
chr6_-_10415043 0.10 ENST00000379613.10
transcription factor AP-2 alpha
chr6_+_43771960 0.10 ENST00000230480.10
vascular endothelial growth factor A
chr17_+_16217198 0.10 ENST00000581006.5
ENST00000584797.5
ENST00000225609.10
ENST00000395844.8
ENST00000463810.2
phosphatidylinositol glycan anchor biosynthesis class L
chr8_+_79611036 0.10 ENST00000220876.12
ENST00000518111.5
stathmin 2
chr9_+_122614738 0.10 ENST00000297913.3
olfactory receptor family 1 subfamily Q member 1
chr12_-_109309278 0.10 ENST00000299162.10
forkhead box N4
chr14_+_75069632 0.10 ENST00000439583.2
ENST00000554763.2
ENST00000524913.3
ENST00000525046.2
ENST00000674086.1
ENST00000526130.2
ENST00000674094.1
ENST00000532198.2
zinc finger C2HC-type containing 1C
chr18_+_79395942 0.10 ENST00000397790.6
nuclear factor of activated T cells 1
chr1_+_174877430 0.10 ENST00000392064.6
RAB GTPase activating protein 1 like
chr2_+_102355881 0.10 ENST00000409599.5
interleukin 18 receptor 1
chr14_-_21094488 0.09 ENST00000555270.5
zinc finger protein 219
chr1_-_153549120 0.09 ENST00000368712.1
S100 calcium binding protein A3
chr20_+_1894145 0.09 ENST00000400068.7
signal regulatory protein alpha
chr4_-_119322128 0.09 ENST00000274024.4
fatty acid binding protein 2
chr18_-_55402187 0.09 ENST00000630268.2
ENST00000570177.6
transcription factor 4
chr4_+_154743993 0.09 ENST00000336356.4
lecithin retinol acyltransferase
chr14_-_23577457 0.09 ENST00000622501.4
junctophilin 4
chr11_-_57322197 0.09 ENST00000532437.1
tankyrase 1 binding protein 1
chr12_-_109309218 0.09 ENST00000355216.5
forkhead box N4
chr10_+_46375721 0.09 ENST00000616785.1
ENST00000611655.1
ENST00000619162.5
novel transcript
annexin A8 like 1
chr6_-_27873525 0.09 ENST00000618305.2
H4 clustered histone 13
chrX_+_136648214 0.09 ENST00000370628.2
CD40 ligand
chr3_-_27722316 0.09 ENST00000449599.4
eomesodermin
chr1_+_67166448 0.09 ENST00000347310.10
interleukin 23 receptor
chr10_+_69801874 0.09 ENST00000357811.8
collagen type XIII alpha 1 chain
chr8_-_90082871 0.09 ENST00000265431.7
calbindin 1
chrX_+_136648138 0.09 ENST00000370629.7
CD40 ligand
chr12_+_11649666 0.09 ENST00000396373.9
ETS variant transcription factor 6
chr18_-_55351977 0.09 ENST00000643689.1
transcription factor 4
chr17_-_7294592 0.09 ENST00000007699.10
Y-box binding protein 2
chr11_+_9461003 0.09 ENST00000438144.6
ENST00000396602.7
ENST00000526657.5
ENST00000299606.6
ENST00000534265.5
ENST00000412390.6
zinc finger protein 143
chr4_-_142305826 0.09 ENST00000514525.1
inositol polyphosphate-4-phosphatase type II B
chr20_+_1894462 0.08 ENST00000622179.4
signal regulatory protein alpha
chr17_-_40867200 0.08 ENST00000647902.1
ENST00000251643.5
keratin 12
chr1_-_146021724 0.08 ENST00000475797.1
ENST00000497365.5
ENST00000336751.11
ENST00000634927.1
ENST00000421822.2
hemojuvelin BMP co-receptor
chr8_-_85341705 0.08 ENST00000517618.5
carbonic anhydrase 1
chr17_+_29246852 0.08 ENST00000225387.8
crystallin beta A1
chr8_+_100158576 0.08 ENST00000388798.7
sperm associated antigen 1
chr5_+_140855882 0.08 ENST00000562220.2
ENST00000307360.6
ENST00000506939.6
protocadherin alpha 10
chr10_-_67696115 0.08 ENST00000433211.7
catenin alpha 3
chr13_-_46142834 0.08 ENST00000674665.1
lymphocyte cytosolic protein 1
chr18_-_55589795 0.08 ENST00000568740.5
ENST00000629387.2
transcription factor 4
chr6_-_134950081 0.08 ENST00000367847.2
ENST00000265605.7
ENST00000367845.6
aldehyde dehydrogenase 8 family member A1
chr3_-_27722699 0.08 ENST00000461503.2
eomesodermin
chr11_+_18396266 0.08 ENST00000540430.5
ENST00000379412.9
lactate dehydrogenase A
chr1_-_153549238 0.08 ENST00000368713.8
S100 calcium binding protein A3

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC2_NFATC3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.2 0.6 GO:0060279 positive regulation of ovulation(GO:0060279)
0.2 0.8 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.1 0.4 GO:0035627 ceramide transport(GO:0035627)
0.1 0.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.2 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.3 GO:1902617 response to fluoride(GO:1902617)
0.1 0.3 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0032439 endosome localization(GO:0032439)
0.1 0.2 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.1 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.7 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.2 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.1 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.3 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.3 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0 0.3 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.1 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.1 GO:0036304 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
0.0 0.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.1 GO:0060948 coronary vein morphogenesis(GO:0003169) cardiac vascular smooth muscle cell development(GO:0060948) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.2 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.3 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 5.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.2 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:1904253 circadian temperature homeostasis(GO:0060086) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.1 GO:1902809 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:2000724 mineralocorticoid receptor signaling pathway(GO:0031959) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.1 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023) activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0 0.1 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.0 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 0.1 GO:0003358 noradrenergic neuron development(GO:0003358)
0.0 0.7 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.2 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.0 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:2000020 positive regulation of male gonad development(GO:2000020)
0.0 0.1 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 0.1 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.0 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.2 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.0 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860) regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0043696 forebrain anterior/posterior pattern specification(GO:0021797) dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.0 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.0 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 0.1 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.2 GO:0071754 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.1 0.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.2 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.5 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 1.1 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.1 GO:0044307 dendritic branch(GO:0044307)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.4 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.4 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.1 0.3 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.2 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.2 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.6 GO:0019534 toxin transporter activity(GO:0019534)
0.1 1.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:1902271 D3 vitamins binding(GO:1902271)
0.0 0.2 GO:0019862 IgA binding(GO:0019862)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.4 GO:0019841 retinol binding(GO:0019841)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0008513 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.1 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.0 GO:0032428 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.0 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.4 GO:0032452 histone demethylase activity(GO:0032452)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation