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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NFE2L1

Z-value: 2.24

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Transcription factors associated with NFE2L1

Gene Symbol Gene ID Gene Info
ENSG00000082641.16 nuclear factor, erythroid 2 like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFE2L1hg38_v1_chr17_+_48048345_48048384,
hg38_v1_chr17_+_48048773_48048790
0.521.8e-01Click!

Activity profile of NFE2L1 motif

Sorted Z-values of NFE2L1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_52493250 4.06 ENST00000330722.7
keratin 6A
chr2_-_160200310 2.90 ENST00000620391.4
integrin subunit beta 6
chr2_-_160200251 2.88 ENST00000428609.6
ENST00000409967.6
ENST00000283249.7
integrin subunit beta 6
chr2_-_160200289 2.77 ENST00000409872.1
integrin subunit beta 6
chr11_+_118077009 1.81 ENST00000616579.4
ENST00000534111.5
transmembrane serine protease 4
chr5_+_36608146 1.80 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr2_-_112836702 1.68 ENST00000416750.1
ENST00000263341.7
ENST00000418817.5
interleukin 1 beta
chr19_-_35501878 1.48 ENST00000593342.5
ENST00000601650.1
ENST00000408915.6
dermokine
chr11_+_118077067 1.45 ENST00000522307.5
ENST00000523251.5
ENST00000437212.8
ENST00000522824.5
ENST00000522151.5
transmembrane serine protease 4
chr10_-_121598359 1.40 ENST00000684153.1
fibroblast growth factor receptor 2
chr5_+_140868945 1.38 ENST00000398640.7
protocadherin alpha 11
chr5_+_167754918 1.37 ENST00000519204.5
teneurin transmembrane protein 2
chr3_-_151316795 1.27 ENST00000260843.5
G protein-coupled receptor 87
chr1_+_34755039 1.26 ENST00000338513.1
gap junction protein beta 5
chr10_-_121598412 1.25 ENST00000360144.7
ENST00000358487.10
ENST00000369059.5
ENST00000613048.4
ENST00000356226.8
fibroblast growth factor receptor 2
chr12_-_122716790 1.15 ENST00000528880.3
hydroxycarboxylic acid receptor 3
chr3_-_56775657 1.15 ENST00000413728.6
Rho guanine nucleotide exchange factor 3
chr11_-_108593738 1.09 ENST00000525344.5
ENST00000265843.9
exophilin 5
chr11_-_120128831 1.04 ENST00000529044.5
tripartite motif containing 29
chr12_+_40692413 1.04 ENST00000551295.7
ENST00000547702.5
ENST00000551424.5
contactin 1
chr11_+_35180342 0.99 ENST00000639002.1
CD44 molecule (Indian blood group)
chr2_-_164621461 0.99 ENST00000446413.6
ENST00000263915.8
growth factor receptor bound protein 14
chr12_-_122703346 0.96 ENST00000328880.6
hydroxycarboxylic acid receptor 2
chr7_-_41703062 0.94 ENST00000242208.5
inhibin subunit beta A
chr18_+_36544544 0.92 ENST00000591635.5
formin homology 2 domain containing 3
chr1_-_99766620 0.91 ENST00000646001.2
ferric chelate reductase 1
chr10_+_80413817 0.90 ENST00000372187.9
peroxiredoxin like 2A
chr6_-_52244500 0.89 ENST00000336123.5
interleukin 17F
chr4_-_122621011 0.89 ENST00000611104.2
ENST00000648588.1
interleukin 21
chr6_-_32816910 0.88 ENST00000447394.1
ENST00000438763.7
major histocompatibility complex, class II, DO beta
chr19_+_14941489 0.86 ENST00000248072.3
olfactory receptor family 7 subfamily C member 2
chr11_-_88175432 0.85 ENST00000531138.1
ENST00000526372.1
ENST00000243662.11
RAB38, member RAS oncogene family
chr10_-_121598396 0.85 ENST00000336553.10
ENST00000457416.6
fibroblast growth factor receptor 2
chr18_+_58221535 0.82 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr6_-_11807045 0.82 ENST00000379415.6
androgen dependent TFPI regulating protein
chr10_-_121598234 0.78 ENST00000369058.7
ENST00000369060.8
ENST00000359354.6
fibroblast growth factor receptor 2
chr11_+_59713403 0.77 ENST00000641815.1
syntaxin 3
chr1_+_43269974 0.75 ENST00000439858.6
transmembrane protein 125
chr1_+_43270007 0.75 ENST00000432792.6
transmembrane protein 125
chr11_+_7605719 0.75 ENST00000530181.5
PPFIA binding protein 2
chr15_+_88639009 0.74 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr9_-_39239174 0.74 ENST00000358144.6
contactin associated protein family member 3
chr11_+_35176575 0.73 ENST00000526000.6
CD44 molecule (Indian blood group)
chr16_+_67199104 0.72 ENST00000360833.6
ENST00000652269.1
ENST00000393997.8
engulfment and cell motility 3
chr6_-_2841853 0.71 ENST00000380739.6
serpin family B member 1
chr6_-_29375291 0.70 ENST00000396806.3
olfactory receptor family 12 subfamily D member 3
chr16_+_67199509 0.70 ENST00000477898.5
engulfment and cell motility 3
chr8_+_103819244 0.67 ENST00000262231.14
ENST00000507740.5
ENST00000408894.6
regulating synaptic membrane exocytosis 2
chr9_-_115091018 0.67 ENST00000542877.5
ENST00000537320.5
ENST00000341037.8
tenascin C
chr6_-_155455830 0.63 ENST00000159060.3
NADPH oxidase 3
chr9_-_114387973 0.61 ENST00000374088.8
AT-hook transcription factor
chr1_-_205994439 0.58 ENST00000617991.4
RAB7B, member RAS oncogene family
chr15_+_90184912 0.58 ENST00000561085.1
ENST00000332496.10
semaphorin 4B
chr5_-_16508858 0.57 ENST00000684456.1
reticulophagy regulator 1
chr5_-_16508951 0.57 ENST00000682628.1
reticulophagy regulator 1
chr5_-_16508812 0.57 ENST00000683414.1
reticulophagy regulator 1
chr3_-_98522514 0.56 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
claudin domain containing 1
chr19_-_43656616 0.56 ENST00000593447.5
plasminogen activator, urokinase receptor
chr13_-_51974775 0.55 ENST00000674147.1
ATPase copper transporting beta
chr18_+_58362467 0.55 ENST00000675101.1
NEDD4 like E3 ubiquitin protein ligase
chr9_-_124500986 0.55 ENST00000373587.3
nuclear receptor subfamily 5 group A member 1
chr21_-_40847149 0.54 ENST00000400454.6
DS cell adhesion molecule
chr18_-_55423757 0.54 ENST00000675707.1
transcription factor 4
chr16_+_57628684 0.54 ENST00000567397.5
ENST00000568979.5
ENST00000672974.1
adhesion G protein-coupled receptor G1
chr5_-_16508990 0.52 ENST00000399793.6
reticulophagy regulator 1
chr5_-_16508788 0.52 ENST00000682142.1
reticulophagy regulator 1
chr4_-_6070162 0.51 ENST00000636216.1
ENST00000637373.2
novel protein
janus kinase and microtubule interacting protein 1
chr12_-_104958268 0.51 ENST00000432951.1
ENST00000258538.8
ENST00000415674.1
ENST00000424946.1
ENST00000433540.5
solute carrier family 41 member 2
chr15_+_88638947 0.51 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr19_+_10654261 0.46 ENST00000449870.5
interleukin enhancer binding factor 3
chr9_-_129753023 0.46 ENST00000340607.5
prostaglandin E synthase
chrX_-_13319952 0.46 ENST00000622204.1
ENST00000380622.5
ataxin 3 like
chr7_+_151114597 0.46 ENST00000335367.7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr11_+_72114840 0.46 ENST00000622388.4
folate receptor gamma
chr12_-_39340963 0.44 ENST00000552961.5
kinesin family member 21A
chrX_-_33211540 0.44 ENST00000357033.9
dystrophin
chr12_+_20810698 0.44 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr12_-_122896066 0.43 ENST00000267202.7
ENST00000535765.5
VPS37B subunit of ESCRT-I
chr20_+_9069076 0.42 ENST00000378473.9
phospholipase C beta 4
chr11_+_35176611 0.40 ENST00000279452.10
CD44 molecule (Indian blood group)
chr6_+_29306626 0.40 ENST00000377160.4
olfactory receptor family 14 subfamily J member 1
chr5_+_148202771 0.39 ENST00000514389.5
ENST00000621437.4
serine peptidase inhibitor Kazal type 6
chr9_+_128882502 0.38 ENST00000259324.5
leucine rich repeat containing 8 VRAC subunit A
chr6_+_143864458 0.38 ENST00000237275.9
zinc finger C2HC-type containing 1B
chr20_+_62656359 0.38 ENST00000370507.5
solute carrier organic anion transporter family member 4A1
chr2_+_112977998 0.38 ENST00000259205.5
ENST00000376489.6
interleukin 36 gamma
chr11_+_6845683 0.38 ENST00000299454.5
olfactory receptor family 10 subfamily A member 5
chr14_+_22226711 0.37 ENST00000390463.3
T cell receptor alpha variable 36/delta variable 7
chr4_-_80073057 0.37 ENST00000681710.1
ANTXR cell adhesion molecule 2
chr4_+_87975829 0.36 ENST00000614857.5
secreted phosphoprotein 1
chr6_-_56642788 0.36 ENST00000439203.5
ENST00000518935.5
ENST00000370765.11
ENST00000244364.10
dystonin
chr3_-_27722699 0.36 ENST00000461503.2
eomesodermin
chr9_+_136952896 0.35 ENST00000371632.7
lipocalin 12
chr22_+_37906275 0.35 ENST00000215957.10
ENST00000445494.6
ENST00000680578.1
ENST00000424008.2
MICAL like 1
chr1_-_113887375 0.34 ENST00000471267.1
ENST00000393320.3
BCL2 like 15
chr14_+_23372809 0.34 ENST00000397242.2
ENST00000329715.2
interleukin 25
chr18_-_55403682 0.34 ENST00000564228.5
ENST00000630828.2
transcription factor 4
chr19_-_54063905 0.34 ENST00000645936.1
ENST00000376626.5
ENST00000366170.6
ENST00000425006.3
V-set and transmembrane domain containing 1
chr8_+_127735597 0.33 ENST00000651626.1
MYC proto-oncogene, bHLH transcription factor
chr7_-_135211313 0.33 ENST00000682802.1
ENST00000683848.1
ENST00000354475.5
WD repeat domain 91
chr10_+_5524953 0.33 ENST00000315238.3
calmodulin like 3
chr17_-_59707404 0.33 ENST00000393038.3
peptidyl-tRNA hydrolase 2
chr3_-_27484374 0.32 ENST00000445684.5
ENST00000425128.6
solute carrier family 4 member 7
chr11_+_35189964 0.32 ENST00000524922.1
CD44 molecule (Indian blood group)
chr6_+_111259294 0.32 ENST00000672303.1
ENST00000671876.2
ENST00000368847.5
major facilitator superfamily domain containing 4B
chr11_+_35189869 0.32 ENST00000525688.5
ENST00000278385.10
ENST00000533222.5
CD44 molecule (Indian blood group)
chr6_+_155264013 0.32 ENST00000367165.3
claudin 20
chr19_+_42269219 0.32 ENST00000681038.1
capicua transcriptional repressor
chr2_-_99255107 0.32 ENST00000333017.6
ENST00000626374.2
ENST00000409679.5
ENST00000423306.1
lysozyme g2
chr9_+_27524285 0.32 ENST00000276943.3
interferon kappa
chr14_+_22271921 0.31 ENST00000390464.2
T cell receptor alpha variable 38-1
chr1_-_40097216 0.31 ENST00000641083.1
ENST00000641471.1
ENST00000642050.2
ENST00000433473.8
ENST00000439754.6
ENST00000527311.7
ENST00000641319.1
ENST00000449045.7
palmitoyl-protein thioesterase 1
chr19_-_35528221 0.31 ENST00000588674.5
ENST00000452271.7
ENST00000518157.1
suprabasin
chr6_+_150683593 0.31 ENST00000644968.1
pleckstrin homology and RhoGEF domain containing G1
chr1_-_109397888 0.31 ENST00000256637.8
sortilin 1
chr3_-_143848442 0.31 ENST00000474151.1
ENST00000316549.11
solute carrier family 9 member A9
chr2_-_74553934 0.30 ENST00000264094.8
ENST00000393937.6
ENST00000409986.5
lysyl oxidase like 3
chr11_+_55827219 0.30 ENST00000378397.1
olfactory receptor family 5 subfamily L member 2
chr22_+_32043253 0.30 ENST00000266088.9
solute carrier family 5 member 1
chrX_+_135520616 0.29 ENST00000370752.4
ENST00000639893.2
integrator complex subunit 6 like
chr4_+_86594301 0.29 ENST00000427191.6
ENST00000411767.7
ENST00000436978.5
ENST00000502971.5
protein tyrosine phosphatase non-receptor type 13
chr4_-_826092 0.29 ENST00000505203.1
complexin 1
chr15_+_45114324 0.29 ENST00000323030.6
dual oxidase maturation factor 2
chr4_+_70334963 0.29 ENST00000273936.6
calcium binding protein, spermatid associated 1
chr12_-_18738006 0.29 ENST00000266505.12
ENST00000543242.5
ENST00000539072.5
ENST00000541966.5
ENST00000648272.1
phospholipase C zeta 1
chr7_+_832470 0.28 ENST00000401592.6
Sad1 and UNC84 domain containing 1
chr17_-_75667088 0.28 ENST00000578201.5
ENST00000423245.6
ENST00000317905.10
RecQ like helicase 5
chr10_-_112183698 0.28 ENST00000369425.5
ENST00000348367.9
glycerol-3-phosphate acyltransferase, mitochondrial
chr3_-_190449782 0.27 ENST00000354905.3
transmembrane protein 207
chr2_-_46542555 0.27 ENST00000522587.6
ATPase H+ transporting V1 subunit E2
chr3_-_52409783 0.27 ENST00000470173.1
ENST00000296288.9
ENST00000460680.6
BRCA1 associated protein 1
chr9_+_131096476 0.27 ENST00000372309.7
ENST00000247291.8
ENST00000372302.5
ENST00000372300.5
ENST00000372298.1
allograft inflammatory factor 1 like
chr3_-_27484335 0.27 ENST00000454389.5
ENST00000440156.5
ENST00000437179.5
ENST00000446700.5
ENST00000455077.5
solute carrier family 4 member 7
chr12_+_28190420 0.26 ENST00000539107.5
ENST00000545336.5
coiled-coil domain containing 91
chr17_+_59220446 0.26 ENST00000284116.9
ENST00000581140.5
ENST00000581276.5
glycerophosphodiester phosphodiesterase domain containing 1
chr1_+_84164684 0.26 ENST00000370680.5
protein kinase cAMP-activated catalytic subunit beta
chr14_+_22508602 0.26 ENST00000390504.1
T cell receptor alpha joining 33
chr9_+_122519141 0.26 ENST00000340750.1
olfactory receptor family 1 subfamily J member 4
chr11_+_59787067 0.26 ENST00000528805.1
syntaxin 3
chr17_-_7252054 0.26 ENST00000575783.5
ENST00000573600.5
CTD nuclear envelope phosphatase 1
chr11_+_60429595 0.26 ENST00000528905.1
ENST00000528093.1
membrane spanning 4-domains A5
chr3_+_130931893 0.26 ENST00000504612.5
ATPase secretory pathway Ca2+ transporting 1
chr1_+_99970430 0.26 ENST00000370153.6
solute carrier family 35 member A3
chr18_+_58195390 0.26 ENST00000456173.6
ENST00000676226.1
ENST00000675865.1
NEDD4 like E3 ubiquitin protein ligase
chr3_-_108529322 0.25 ENST00000273353.4
myosin heavy chain 15
chr2_+_181985846 0.25 ENST00000682840.1
ENST00000409137.7
ENST00000280295.7
protein phosphatase 1 regulatory inhibitor subunit 1C
chr13_-_46897021 0.25 ENST00000542664.4
ENST00000543956.5
5-hydroxytryptamine receptor 2A
chr3_-_98522869 0.25 ENST00000502288.5
ENST00000512147.5
ENST00000341181.11
ENST00000510541.5
ENST00000503621.5
ENST00000511081.5
ENST00000507874.5
ENST00000502299.5
ENST00000508659.5
ENST00000510545.5
ENST00000511667.5
ENST00000394185.6
claudin domain containing 1
chr4_-_826113 0.25 ENST00000304062.11
complexin 1
chr11_-_129024157 0.25 ENST00000392657.7
Rho GTPase activating protein 32
chr2_+_181986015 0.25 ENST00000409702.1
protein phosphatase 1 regulatory inhibitor subunit 1C
chr4_-_7068033 0.24 ENST00000264954.5
GrpE like 1, mitochondrial
chr8_-_123025750 0.24 ENST00000523036.1
derlin 1
chr1_-_11805924 0.24 ENST00000418034.1
methylenetetrahydrofolate reductase
chrX_+_100666854 0.24 ENST00000640282.1
sushi repeat containing protein X-linked 2
chr1_-_112715469 0.23 ENST00000309276.10
protein phosphatase, Mg2+/Mn2+ dependent 1J
chr15_+_80072559 0.23 ENST00000560228.5
ENST00000559835.5
ENST00000559775.5
ENST00000558688.5
ENST00000560392.5
ENST00000560976.5
ENST00000558272.5
ENST00000558390.5
zinc finger AN1-type containing 6
chr19_+_50203607 0.23 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
myosin heavy chain 14
chr7_+_107580454 0.23 ENST00000379117.6
ENST00000473124.1
B cell receptor associated protein 29
chrX_-_78659328 0.22 ENST00000321110.2
retrotransposon Gag like 3
chr5_+_179793978 0.22 ENST00000292596.15
ENST00000401985.3
leukotriene C4 synthase
chr14_-_24299707 0.22 ENST00000288111.12
dehydrogenase/reductase 1
chrX_-_100636799 0.22 ENST00000373020.9
tetraspanin 6
chr6_-_49636832 0.22 ENST00000371175.10
ENST00000646272.1
ENST00000646939.1
ENST00000618248.3
ENST00000229810.9
ENST00000646963.1
Rh associated glycoprotein
chr22_-_37953541 0.22 ENST00000422191.1
ENST00000249079.6
ENST00000403305.6
ENST00000418863.5
ENST00000619227.4
ENST00000403026.5
chromosome 22 open reading frame 23
chr1_+_159439722 0.22 ENST00000641630.1
ENST00000423932.6
olfactory receptor family 10 subfamily J member 1
chr1_-_11805949 0.22 ENST00000376590.9
methylenetetrahydrofolate reductase
chr6_+_52186373 0.21 ENST00000648244.1
interleukin 17A
chr11_+_35176696 0.21 ENST00000528455.5
CD44 molecule (Indian blood group)
chr7_+_107580215 0.21 ENST00000465919.5
ENST00000005259.9
ENST00000445771.6
ENST00000479917.5
ENST00000421217.5
ENST00000457837.5
B cell receptor associated protein 29
chr4_-_86594037 0.21 ENST00000641050.1
ENST00000641831.1
ENST00000515400.3
ENST00000641391.1
ENST00000641157.1
ENST00000641737.1
ENST00000502302.6
ENST00000640527.1
ENST00000512046.2
ENST00000513186.7
mitogen-activated protein kinase 10
chr10_+_69180226 0.21 ENST00000359655.9
ENST00000422378.1
Suv3 like RNA helicase
chr11_+_63369779 0.21 ENST00000279178.4
solute carrier family 22 member 9
chr11_-_107858777 0.21 ENST00000525815.6
solute carrier family 35 member F2
chr11_+_60429567 0.20 ENST00000300190.7
membrane spanning 4-domains A5
chr7_+_42932346 0.20 ENST00000223324.3
mitochondrial ribosomal protein L32
chr10_+_5446601 0.20 ENST00000449083.5
ENST00000380359.3
neuroepithelial cell transforming 1
chr11_+_35176639 0.20 ENST00000527889.6
CD44 molecule (Indian blood group)
chr1_-_202808464 0.20 ENST00000648469.1
ENST00000648338.1
ENST00000367264.7
ENST00000648473.1
ENST00000648056.1
ENST00000650368.1
lysine demethylase 5B
chr9_+_84668485 0.20 ENST00000359847.4
ENST00000395882.6
ENST00000376208.6
ENST00000376213.6
neurotrophic receptor tyrosine kinase 2
chr19_-_12696581 0.20 ENST00000587955.1
ENST00000393261.8
F-box and WD repeat domain containing 9
chr5_+_66144204 0.20 ENST00000612404.4
splicing regulatory glutamic acid and lysine rich protein 1
chr12_-_14951106 0.20 ENST00000541644.5
ENST00000545895.5
Rho GDP dissociation inhibitor beta
chr15_-_43106022 0.20 ENST00000627960.1
ENST00000290650.9
ubiquitin protein ligase E3 component n-recognin 1
chr6_-_10838503 0.20 ENST00000536370.6
ENST00000474039.5
ENST00000354489.7
ENST00000676116.1
male germ cell associated kinase
chr1_-_10982037 0.20 ENST00000377004.8
chromosome 1 open reading frame 127
chr2_-_218659468 0.20 ENST00000450560.1
ENST00000449707.5
ENST00000440934.2
zinc finger protein 142
chr2_+_158795309 0.19 ENST00000309950.8
ENST00000621326.4
ENST00000409042.5
death associated protein like 1
chr17_-_67996428 0.19 ENST00000580729.3
chromosome 17 open reading frame 58
chr11_-_66907891 0.19 ENST00000393955.6
pyruvate carboxylase
chr22_+_30409097 0.19 ENST00000439838.5
ENST00000439023.3
novel SEC14-like 2 (S. cerevisiae) (SEC14L2) and mitochondrial protein 18 kDa (MTP18) protein
chr7_-_122304499 0.19 ENST00000427185.2
FEZ family zinc finger 1
chr5_-_37371061 0.19 ENST00000513532.1
ENST00000231498.8
nucleoporin 155
chr4_-_164383986 0.18 ENST00000507270.5
ENST00000514618.5
ENST00000503008.5
membrane associated ring-CH-type finger 1
chr4_-_154590735 0.18 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
fibrinogen alpha chain
chr9_+_122264857 0.18 ENST00000344641.8
ENST00000441707.5
ENST00000373723.9
ENST00000373729.5
mitochondrial ribosome recycling factor
chr14_-_21022817 0.18 ENST00000554104.5
NDRG family member 2
chr17_+_28335571 0.18 ENST00000544907.6
TNF alpha induced protein 1
chr15_-_48963912 0.18 ENST00000332408.9
SHC adaptor protein 4
chr3_+_47380995 0.18 ENST00000456221.5
ENST00000265562.5
protein tyrosine phosphatase non-receptor type 23

Network of associatons between targets according to the STRING database.

First level regulatory network of NFE2L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.8 8.6 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.7 4.3 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.6 1.7 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.4 1.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.3 2.8 GO:0061709 reticulophagy(GO:0061709)
0.3 1.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.3 0.9 GO:0060279 positive regulation of ovulation(GO:0060279)
0.3 1.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 0.9 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2 3.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 0.7 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.2 1.0 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 0.6 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.2 0.6 GO:0060003 copper ion export(GO:0060003)
0.2 1.8 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.2 0.9 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.2 0.4 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.6 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.4 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.5 GO:0007538 primary sex determination(GO:0007538)
0.1 1.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.8 GO:1903232 melanosome assembly(GO:1903232)
0.1 1.0 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.3 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.8 GO:0070827 chromatin maintenance(GO:0070827)
0.1 0.4 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.3 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.3 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.7 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.3 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.6 GO:0048840 otolith development(GO:0048840)
0.1 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.4 GO:0007343 egg activation(GO:0007343)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.1 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.1 0.2 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 1.3 GO:0097264 self proteolysis(GO:0097264)
0.1 0.1 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.1 0.4 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.1 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.1 0.6 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.3 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.1 0.3 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.9 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 1.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.1 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.2 GO:2000861 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.1 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.2 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.1 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.3 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.5 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.3 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.7 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
0.0 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.3 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.1 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.5 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.2 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.3 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.0 0.5 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0045007 depurination(GO:0045007)
0.0 0.2 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0042335 cuticle development(GO:0042335) hypophysis morphogenesis(GO:0048850)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0015884 folic acid transport(GO:0015884)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.3 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 3.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0033504 floor plate development(GO:0033504)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.0 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.2 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.1 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
0.0 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.1 GO:0019376 galactolipid catabolic process(GO:0019376)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.0 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0031622 positive regulation of fever generation(GO:0031622)
0.0 0.1 GO:0072719 cellular response to cisplatin(GO:0072719)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.6 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.3 0.9 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 3.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 1.0 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.2 0.9 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.5 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 1.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 3.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.1 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 1.6 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 1.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 2.6 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.0 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 4.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 0.9 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.2 0.6 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 1.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.9 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 1.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 2.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.6 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.5 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.8 GO:0045545 syndecan binding(GO:0045545)
0.1 0.3 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 3.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 8.9 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 1.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.8 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.2 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.8 GO:0005549 odorant binding(GO:0005549)
0.0 1.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 4.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 2.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 1.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:0004487 formate-tetrahydrofolate ligase activity(GO:0004329) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 5.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 4.4 PID FGF PATHWAY FGF signaling pathway
0.0 1.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 3.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 9.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.0 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 1.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 2.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex