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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NKX2-2

Z-value: 0.72

Motif logo

Transcription factors associated with NKX2-2

Gene Symbol Gene ID Gene Info
ENSG00000125820.6 NK2 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-2hg38_v1_chr20_-_21514046_21514070-0.049.2e-01Click!

Activity profile of NKX2-2 motif

Sorted Z-values of NKX2-2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_121641424 0.97 ENST00000303924.5
hyaluronan synthase 2
chr4_-_155866277 0.70 ENST00000537611.3
acid sensing ion channel subunit family member 5
chr5_+_83471764 0.61 ENST00000512590.6
ENST00000513960.5
ENST00000513984.5
versican
chr5_+_83471668 0.60 ENST00000342785.8
ENST00000343200.9
versican
chr5_+_83471925 0.59 ENST00000502527.2
versican
chr5_+_83471736 0.56 ENST00000265077.8
versican
chr6_+_151239951 0.54 ENST00000402676.7
A-kinase anchoring protein 12
chr13_+_101489940 0.51 ENST00000376162.7
integrin subunit beta like 1
chr1_+_171512032 0.50 ENST00000426496.6
proline rich coiled-coil 2C
chr7_-_138627444 0.46 ENST00000463557.1
SVOP like
chr8_+_76681208 0.40 ENST00000651372.2
zinc finger homeobox 4
chr8_+_96584920 0.40 ENST00000521590.5
syndecan 2
chrX_+_101488044 0.38 ENST00000423738.4
armadillo repeat containing X-linked 4
chr14_+_64113084 0.37 ENST00000673797.1
spectrin repeat containing nuclear envelope protein 2
chr13_+_101452569 0.37 ENST00000618057.4
integrin subunit beta like 1
chrM_+_12329 0.37 ENST00000361567.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5
chr17_-_31314040 0.37 ENST00000330927.5
ecotropic viral integration site 2B
chr1_+_78303865 0.37 ENST00000370758.5
prostaglandin F receptor
chr2_+_151357583 0.36 ENST00000243347.5
TNF alpha induced protein 6
chr13_+_101452629 0.36 ENST00000622834.4
ENST00000545560.6
ENST00000376180.8
integrin subunit beta like 1
chr4_-_98657635 0.35 ENST00000515287.5
ENST00000511651.5
ENST00000505184.5
tetraspanin 5
chr10_-_77637721 0.33 ENST00000638848.1
ENST00000639406.1
ENST00000618048.2
ENST00000639120.1
ENST00000640834.1
ENST00000639601.1
ENST00000638514.1
ENST00000457953.6
ENST00000639090.1
ENST00000639489.1
ENST00000372440.6
ENST00000404771.8
ENST00000638203.1
ENST00000638306.1
ENST00000638351.1
ENST00000638606.1
ENST00000639591.1
ENST00000640182.1
ENST00000640605.1
ENST00000640141.1
potassium calcium-activated channel subfamily M alpha 1
chr12_-_119877270 0.31 ENST00000261833.11
ENST00000612548.4
citron rho-interacting serine/threonine kinase
chr19_-_14778552 0.31 ENST00000315576.8
adhesion G protein-coupled receptor E2
chr6_+_29301701 0.31 ENST00000641895.1
olfactory receptor family 14 subfamily J member 1
chr19_-_43670153 0.31 ENST00000601723.5
ENST00000339082.7
ENST00000340093.8
plasminogen activator, urokinase receptor
chr7_-_93226449 0.30 ENST00000394468.7
ENST00000453812.2
HEPACAM family member 2
chr1_+_101238090 0.30 ENST00000475289.2
sphingosine-1-phosphate receptor 1
chr3_-_33645253 0.29 ENST00000333778.10
cytoplasmic linker associated protein 2
chr12_-_89656093 0.29 ENST00000359142.7
ATPase plasma membrane Ca2+ transporting 1
chr1_-_72100930 0.29 ENST00000306821.3
neuronal growth regulator 1
chr10_-_77637789 0.28 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
potassium calcium-activated channel subfamily M alpha 1
chr12_-_119877300 0.28 ENST00000392521.7
citron rho-interacting serine/threonine kinase
chr3_+_189789672 0.28 ENST00000434928.5
tumor protein p63
chr2_-_40512361 0.26 ENST00000403092.5
solute carrier family 8 member A1
chr16_+_53207981 0.25 ENST00000565803.2
chromodomain helicase DNA binding protein 9
chr17_-_69141878 0.25 ENST00000590645.1
ENST00000284425.7
ATP binding cassette subfamily A member 6
chr6_+_151240368 0.25 ENST00000253332.5
A-kinase anchoring protein 12
chr13_+_111114550 0.25 ENST00000317133.9
Rho guanine nucleotide exchange factor 7
chr12_-_102197827 0.25 ENST00000329406.5
pro-melanin concentrating hormone
chr4_+_113292925 0.25 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ankyrin 2
chr4_+_113292838 0.24 ENST00000672411.1
ENST00000673231.1
ankyrin 2
chr14_+_64113054 0.24 ENST00000673869.1
spectrin repeat containing nuclear envelope protein 2
chr8_-_61646807 0.24 ENST00000522919.5
aspartate beta-hydroxylase
chr5_-_78985288 0.23 ENST00000264914.10
arylsulfatase B
chr2_+_151410090 0.22 ENST00000430328.6
replication timing regulatory factor 1
chr1_-_154502402 0.22 ENST00000304760.3
Src homology 2 domain containing E
chr4_-_176195563 0.22 ENST00000280191.7
spermatogenesis associated 4
chr11_+_93746433 0.21 ENST00000526335.1
chromosome 11 open reading frame 54
chr5_+_136058849 0.21 ENST00000508076.5
transforming growth factor beta induced
chr14_-_81533800 0.21 ENST00000555824.5
ENST00000557372.1
ENST00000336735.9
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase
chr9_-_39239174 0.21 ENST00000358144.6
contactin associated protein family member 3
chr17_-_31314066 0.21 ENST00000577894.1
ecotropic viral integration site 2B
chr9_-_21482313 0.21 ENST00000448696.4
interferon epsilon
chr5_+_148826600 0.20 ENST00000305988.6
adrenoceptor beta 2
chr12_-_10826358 0.20 ENST00000240619.2
taste 2 receptor member 10
chr20_+_31514410 0.20 ENST00000335574.10
ENST00000340852.9
ENST00000398174.9
ENST00000466766.2
ENST00000498035.5
ENST00000344042.5
histocompatibility minor 13
chr5_+_136059151 0.20 ENST00000503087.1
transforming growth factor beta induced
chr11_-_790062 0.20 ENST00000330106.5
cell cycle exit and neuronal differentiation 1
chr3_+_63967738 0.19 ENST00000484332.1
ataxin 7
chr5_-_11588842 0.19 ENST00000503622.5
catenin delta 2
chr10_+_13161543 0.19 ENST00000378714.8
ENST00000479669.5
ENST00000484800.6
minichromosome maintenance 10 replication initiation factor
chr14_-_72894091 0.19 ENST00000556509.6
double PHD fingers 3
chr1_+_171557845 0.19 ENST00000644916.1
proline rich coiled-coil 2C
chr11_+_94543894 0.19 ENST00000358752.4
fucosyltransferase 4
chrX_+_83861126 0.18 ENST00000621735.4
ENST00000329312.5
cylicin 1
chr15_-_55917080 0.18 ENST00000506154.1
NEDD4 E3 ubiquitin protein ligase
chr15_-_55917129 0.18 ENST00000338963.6
ENST00000508342.5
NEDD4 E3 ubiquitin protein ligase
chr19_+_57681969 0.18 ENST00000601064.1
ENST00000282296.10
zinc finger protein 551
chr4_+_112818088 0.18 ENST00000673044.1
ENST00000672696.1
ENST00000672315.1
ENST00000672088.1
ENST00000671793.1
ENST00000672402.1
ENST00000671825.1
ENST00000672312.1
ENST00000672830.1
ENST00000672731.1
ENST00000671854.1
ENST00000672350.1
ENST00000672684.1
ENST00000672934.1
ENST00000673546.1
ENST00000673573.1
ENST00000503423.6
ENST00000673255.1
ENST00000671893.1
ENST00000672246.1
ENST00000672930.1
ENST00000673334.1
ENST00000673453.1
ENST00000673555.1
ENST00000672880.1
ENST00000672990.1
ENST00000673430.1
ENST00000673298.1
ENST00000672068.1
ENST00000672362.1
ENST00000672793.1
ENST00000672209.1
ENST00000671756.1
ENST00000671809.1
ENST00000671906.1
ENST00000672090.1
ENST00000672177.1
ENST00000672759.1
ENST00000672965.1
ENST00000673109.1
ENST00000503271.5
ENST00000506722.5
ENST00000673536.1
ENST00000672986.1
ankyrin 2
chr6_+_28281555 0.18 ENST00000259883.3
ENST00000682144.1
piggyBac transposable element derived 1
chr4_+_112818032 0.18 ENST00000672356.1
ENST00000672955.1
ankyrin 2
chrX_-_71254527 0.18 ENST00000373978.1
ENST00000373981.5
zinc finger MYM-type containing 3
chr8_+_31639222 0.18 ENST00000519301.6
ENST00000652698.1
neuregulin 1
chr10_-_103153609 0.17 ENST00000675985.1
5'-nucleotidase, cytosolic II
chr2_-_162152239 0.17 ENST00000418842.7
glucagon
chr1_+_211259932 0.17 ENST00000367005.8
REST corepressor 3
chr7_-_139109702 0.17 ENST00000471652.1
ENST00000242351.10
zinc finger CCCH-type containing, antiviral 1
chr1_+_162632454 0.17 ENST00000367921.8
ENST00000367922.7
discoidin domain receptor tyrosine kinase 2
chr2_-_144517663 0.17 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
zinc finger E-box binding homeobox 2
chr8_+_31639291 0.17 ENST00000651149.1
ENST00000650866.1
neuregulin 1
chr17_+_50746534 0.17 ENST00000511974.5
LUC7 like 3 pre-mRNA splicing factor
chr15_+_65550819 0.17 ENST00000569894.5
3-hydroxyacyl-CoA dehydratase 3
chr4_+_122339221 0.17 ENST00000442707.1
KIAA1109
chr7_+_92057602 0.16 ENST00000491695.2
A-kinase anchoring protein 9
chr5_+_141421020 0.16 ENST00000622044.1
ENST00000398587.7
protocadherin gamma subfamily A, 11
chr9_+_37667997 0.16 ENST00000539465.5
FERM and PDZ domain containing 1
chr5_+_141412979 0.16 ENST00000612503.1
ENST00000398610.3
protocadherin gamma subfamily A, 10
chr12_-_84911178 0.16 ENST00000681688.1
solute carrier family 6 member 15
chr8_-_132760548 0.16 ENST00000519187.5
ENST00000523829.5
ENST00000677595.1
ENST00000356838.7
ENST00000377901.8
ENST00000519304.1
transmembrane protein 71
chr6_+_32439866 0.16 ENST00000374982.5
ENST00000395388.7
major histocompatibility complex, class II, DR alpha
chr2_+_112542413 0.16 ENST00000417433.6
ENST00000263331.10
RNA polymerase I subunit B
chr2_-_162152404 0.15 ENST00000375497.3
glucagon
chr2_-_40512423 0.15 ENST00000402441.5
ENST00000448531.1
solute carrier family 8 member A1
chr7_-_103074816 0.15 ENST00000379305.7
ENST00000379308.7
F-box and leucine rich repeat protein 13
chr17_+_44186953 0.15 ENST00000446571.7
ENST00000538716.7
ENST00000357984.7
transmembrane and ubiquitin like domain containing 2
chr1_-_114695613 0.15 ENST00000369538.4
adenosine monophosphate deaminase 1
chr3_-_33645433 0.15 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr4_+_41935114 0.15 ENST00000508448.5
ENST00000513702.5
ENST00000325094.9
transmembrane protein 33
chr1_-_114695533 0.15 ENST00000520113.7
adenosine monophosphate deaminase 1
chrM_+_4467 0.14 ENST00000361453.3
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
chrX_-_19799751 0.14 ENST00000379698.8
SH3 domain containing kinase binding protein 1
chr2_+_69013379 0.14 ENST00000409349.7
ANTXR cell adhesion molecule 1
chr1_+_161721563 0.14 ENST00000367948.6
Fc receptor like B
chr2_+_151409878 0.14 ENST00000453091.6
ENST00000428287.6
ENST00000444746.7
ENST00000243326.9
ENST00000414861.6
replication timing regulatory factor 1
chr2_+_188292771 0.14 ENST00000359135.7
GULP PTB domain containing engulfment adaptor 1
chr5_-_11589019 0.14 ENST00000511377.5
catenin delta 2
chr20_-_13784880 0.13 ENST00000202816.5
ENST00000617257.2
ESF1 nucleolar pre-rRNA processing protein homolog
chr16_+_30201057 0.13 ENST00000569485.5
sulfotransferase family 1A member 3
chr5_+_141421064 0.13 ENST00000518882.2
protocadherin gamma subfamily A, 11
chr2_+_69013414 0.13 ENST00000681816.1
ENST00000482235.2
ANTXR cell adhesion molecule 1
chr6_+_158536398 0.13 ENST00000367090.4
transmembrane protein 181
chr11_-_125111579 0.13 ENST00000532156.5
ENST00000532407.5
ENST00000279968.8
ENST00000527766.5
ENST00000529583.5
ENST00000524373.5
ENST00000527271.5
ENST00000526175.5
ENST00000529609.5
ENST00000682305.1
ENST00000533273.1
transmembrane protein 218
chr2_+_102337148 0.13 ENST00000311734.6
ENST00000409584.5
interleukin 1 receptor like 1
chr17_-_3063607 0.13 ENST00000575751.1
olfactory receptor family 1 subfamily D member 5
chr10_-_59753388 0.12 ENST00000430431.5
myoregulin
chrX_+_71254781 0.12 ENST00000677446.1
non-POU domain containing octamer binding
chr15_-_56465130 0.12 ENST00000260453.4
meiosis specific nuclear structural 1
chrX_-_23743201 0.12 ENST00000492081.1
ENST00000379303.10
ENST00000336430.11
acyl-CoA thioesterase 9
chrX_+_116436599 0.12 ENST00000598581.3
solute carrier family 6 member 14
chr2_+_188292814 0.12 ENST00000409580.5
ENST00000409637.7
GULP PTB domain containing engulfment adaptor 1
chr6_+_32154010 0.12 ENST00000375137.6
palmitoyl-protein thioesterase 2
chr4_+_36281591 0.12 ENST00000639862.2
ENST00000357504.7
death domain containing 1
chr22_-_23751080 0.12 ENST00000341976.5
zinc finger protein 70
chr3_-_179243284 0.12 ENST00000486944.2
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr9_+_69205141 0.12 ENST00000649134.1
ENST00000539225.2
ENST00000650084.1
ENST00000648402.1
tight junction protein 2
chr6_+_32153441 0.11 ENST00000414204.5
ENST00000361568.6
ENST00000395523.5
palmitoyl-protein thioesterase 2
chr19_+_4402615 0.11 ENST00000301280.10
chromatin assembly factor 1 subunit A
chrX_-_30308333 0.11 ENST00000378963.1
nuclear receptor subfamily 0 group B member 1
chr11_-_56292254 0.11 ENST00000641600.1
olfactory receptor family 8 subfamily H member 1
chrX_+_34942790 0.11 ENST00000329357.6
family with sequence similarity 47 member B
chr16_+_22490337 0.11 ENST00000415833.6
nuclear pore complex interacting protein family member B5
chr7_-_120857124 0.11 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr7_-_103074725 0.11 ENST00000456695.5
ENST00000455112.6
ENST00000440067.2
F-box and leucine rich repeat protein 13
chr6_-_30672984 0.11 ENST00000415603.1
ENST00000376442.8
DEAH-box helicase 16
chr10_-_59753444 0.11 ENST00000594536.5
ENST00000414264.6
myoregulin
chr1_-_202967229 0.11 ENST00000367249.9
cytochrome b5 reductase 1
chr3_-_69052309 0.11 ENST00000398559.7
ENST00000646708.1
ENST00000646304.1
TATA element modulatory factor 1
chr3_-_123620571 0.11 ENST00000583087.5
myosin light chain kinase
chr14_+_39265278 0.11 ENST00000554392.5
ENST00000555716.5
ENST00000341749.7
ENST00000557038.5
MIA SH3 domain ER export factor 2
chr7_-_130441136 0.11 ENST00000675596.1
ENST00000676312.1
centrosomal protein 41
chrX_+_72776873 0.10 ENST00000334036.10
DMRT like family C1B
chr14_-_49688201 0.10 ENST00000553805.2
ENST00000554396.5
ENST00000216367.10
DNA polymerase epsilon 2, accessory subunit
chr12_-_4379712 0.10 ENST00000237837.2
fibroblast growth factor 23
chr4_+_55853639 0.10 ENST00000381295.7
ENST00000346134.11
ENST00000349598.6
exocyst complex component 1
chr10_+_55599041 0.10 ENST00000512524.4
MT-RNR2 like 5
chr8_+_93754879 0.10 ENST00000453906.6
ENST00000683362.1
ENST00000682036.1
ENST00000453321.8
ENST00000409623.8
ENST00000520680.2
ENST00000521517.6
ENST00000452276.6
transmembrane protein 67
chr20_+_18507520 0.10 ENST00000336714.8
ENST00000646240.1
ENST00000450074.6
ENST00000262544.6
SEC23 homolog B, COPII coat complex component
chrX_-_14873027 0.10 ENST00000452869.1
ENST00000398334.5
ENST00000650831.1
ENST00000324138.7
FA complementation group B
chr3_-_123620496 0.10 ENST00000578202.1
myosin light chain kinase
chr13_-_106568107 0.10 ENST00000400198.8
arginine and glutamate rich 1
chr1_+_103617427 0.10 ENST00000423678.2
ENST00000414303.7
amylase alpha 2A
chr5_-_59039454 0.10 ENST00000358923.10
phosphodiesterase 4D
chr5_+_108747879 0.10 ENST00000281092.9
FER tyrosine kinase
chrX_-_72943837 0.10 ENST00000615063.2
DMRT like family C1
chr19_-_39391029 0.10 ENST00000221265.8
PAF1 homolog, Paf1/RNA polymerase II complex component
chr17_+_76376581 0.10 ENST00000591651.5
ENST00000545180.5
sphingosine kinase 1
chr2_-_55049184 0.10 ENST00000357376.7
reticulon 4
chr2_+_169798841 0.09 ENST00000260956.9
ENST00000417292.5
small RNA binding exonuclease protection factor La
chr7_+_32979445 0.09 ENST00000418354.5
ENST00000490776.3
FKBP prolyl isomerase 9
chr17_+_7688427 0.09 ENST00000396463.7
ENST00000534050.5
WD repeat containing antisense to TP53
chr9_-_20622479 0.09 ENST00000380338.9
MLLT3 super elongation complex subunit
chr9_-_15510289 0.09 ENST00000397519.6
PC4 and SFRS1 interacting protein 1
chr6_+_32969345 0.09 ENST00000678250.1
bromodomain containing 2
chrX_-_71254106 0.09 ENST00000373984.7
ENST00000314425.9
ENST00000373982.5
zinc finger MYM-type containing 3
chr4_+_87799546 0.09 ENST00000226284.7
integrin binding sialoprotein
chr1_+_103750406 0.09 ENST00000370079.3
amylase alpha 1C
chr19_-_14835252 0.09 ENST00000641666.1
ENST00000642030.1
ENST00000642000.1
olfactory receptor family 7 subfamily C member 1
chr12_-_111488538 0.09 ENST00000389154.7
ataxin 2
chr19_-_17255448 0.08 ENST00000594059.1
novel protein
chr3_-_151203201 0.08 ENST00000480322.1
ENST00000309180.6
G protein-coupled receptor 171
chr3_-_122416035 0.08 ENST00000330689.6
WD repeat domain 5B
chr2_-_25168690 0.08 ENST00000380794.5
proopiomelanocortin
chr3_+_160225409 0.08 ENST00000326474.5
chromosome 3 open reading frame 80
chr11_-_125111708 0.08 ENST00000531909.5
ENST00000529530.1
transmembrane protein 218
chr21_-_30492008 0.08 ENST00000334063.6
keratin associated protein 19-3
chr19_+_38647679 0.08 ENST00000390009.7
ENST00000589528.1
actinin alpha 4
chr17_+_40015428 0.08 ENST00000394149.8
ENST00000225474.6
ENST00000331769.6
ENST00000394148.7
ENST00000577675.1
colony stimulating factor 3
chr12_+_401621 0.08 ENST00000412006.6
ENST00000239830.9
coiled-coil domain containing 77
chr17_-_40565459 0.08 ENST00000578085.1
ENST00000246657.2
C-C motif chemokine receptor 7
chr5_-_111512473 0.08 ENST00000296632.8
ENST00000512160.5
ENST00000509887.5
StAR related lipid transfer domain containing 4
chr2_-_150487658 0.08 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
Rho family GTPase 3
chr15_-_60398733 0.08 ENST00000559818.6
annexin A2
chr7_+_93906557 0.08 ENST00000248572.10
ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
G protein subunit gamma transducin 1
chr1_-_244862381 0.08 ENST00000640001.1
ENST00000639628.1
heterogeneous nuclear ribonucleoprotein U
chr6_+_32969165 0.08 ENST00000496118.2
ENST00000449085.4
bromodomain containing 2
chr13_-_32538819 0.07 ENST00000674452.1
ENST00000674422.1
ENST00000674349.1
ENST00000674465.1
ENST00000674327.1
ENST00000505213.5
ENST00000357505.10
ENST00000399396.7
NEDD4 binding protein 2 like 2
chr17_+_42854078 0.07 ENST00000591562.1
ENST00000588033.1
amine oxidase copper containing 3
chr3_+_101561833 0.07 ENST00000309922.7
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr5_-_801145 0.07 ENST00000424784.3
zinc finger DHHC-type containing 11
chr9_+_37753798 0.07 ENST00000377753.6
ENST00000537911.5
ENST00000297994.4
ENST00000377754.6
tRNA methyltransferase 10B
chr7_-_13986498 0.07 ENST00000420159.6
ENST00000399357.7
ENST00000403527.5
ETS variant transcription factor 1
chr2_-_25168903 0.07 ENST00000405623.5
proopiomelanocortin
chr9_+_122370523 0.07 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chr12_+_100357068 0.07 ENST00000323346.10
solute carrier family 17 member 8
chr5_-_78985249 0.07 ENST00000565165.2
arylsulfatase B
chr15_-_52652031 0.07 ENST00000546305.6
family with sequence similarity 214 member A
chr17_+_55264952 0.07 ENST00000226067.10
HLF transcription factor, PAR bZIP family member
chrX_+_47232866 0.07 ENST00000218348.7
ENST00000377107.7
ubiquitin specific peptidase 11
chr13_-_32538762 0.07 ENST00000267068.5
ENST00000674428.1
ENST00000674297.1
ENST00000674180.1
ENST00000674421.1
ENST00000674484.1
ENST00000674377.1
NEDD4 binding protein 2 like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.4 GO:0044007 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.1 0.3 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 0.3 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.3 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 2.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.8 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 1.0 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.6 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.4 GO:0008218 bioluminescence(GO:0008218)
0.1 0.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.3 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.2 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.6 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.2 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.3 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.2 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0000964 mitochondrial RNA 5'-end processing(GO:0000964)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:2000843 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 0.3 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:2000547 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.1 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.2 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.0 0.1 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369) response to sodium phosphate(GO:1904383)
0.0 0.1 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.2 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.2 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:1900106 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme morphogenesis(GO:0072134) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0046040 IMP metabolic process(GO:0046040)
0.0 0.2 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.1 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.4 GO:0030728 ovulation(GO:0030728)
0.0 0.3 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043159 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.1 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0044307 dendritic branch(GO:0044307)
0.0 0.4 GO:0001940 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.0 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 3.0 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0031527 filopodium membrane(GO:0031527)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.4 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.3 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.2 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.4 GO:0050816 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.2 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis