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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NKX6-3

Z-value: 0.15

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Transcription factors associated with NKX6-3

Gene Symbol Gene ID Gene Info
ENSG00000165066.13 NK6 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX6-3hg38_v1_chr8_-_41650808_416508220.137.5e-01Click!

Activity profile of NKX6-3 motif

Sorted Z-values of NKX6-3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_49513353 0.08 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr16_+_86566821 0.07 ENST00000649859.1
forkhead box C2
chr10_-_27240505 0.05 ENST00000375888.5
ENST00000676732.1
acyl-CoA binding domain containing 5
chr20_-_35147285 0.05 ENST00000374491.3
ENST00000374492.8
ER degradation enhancing alpha-mannosidase like protein 2
chr6_+_113857333 0.05 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr14_-_50561119 0.05 ENST00000555216.5
mitogen-activated protein kinase kinase kinase kinase 5
chr5_+_141150012 0.04 ENST00000231136.4
ENST00000622991.1
protocadherin beta 6
chr14_+_88385643 0.03 ENST00000393545.9
ENST00000356583.9
ENST00000555401.5
ENST00000553885.5
spermatogenesis associated 7
chr9_+_122371014 0.03 ENST00000362012.7
prostaglandin-endoperoxide synthase 1
chr14_+_88385714 0.03 ENST00000045347.11
spermatogenesis associated 7
chr15_+_92900338 0.03 ENST00000625990.3
chromodomain helicase DNA binding protein 2
chr8_+_76681208 0.03 ENST00000651372.2
zinc finger homeobox 4
chr13_+_53028806 0.02 ENST00000219022.3
olfactomedin 4
chr3_-_165078480 0.02 ENST00000264382.8
sucrase-isomaltase
chr3_-_142000353 0.02 ENST00000499676.5
transcription factor Dp-2
chr11_-_31509569 0.02 ENST00000526776.5
inner mitochondrial membrane peptidase subunit 1
chrX_+_43656289 0.02 ENST00000338702.4
monoamine oxidase A
chr17_+_7407838 0.02 ENST00000302926.7
neuroligin 2
chr20_+_45416551 0.01 ENST00000639292.1
phosphatidylinositol glycan anchor biosynthesis class T
chr3_+_138621225 0.01 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr7_+_138460238 0.01 ENST00000343526.9
tripartite motif containing 24
chr3_-_132684685 0.01 ENST00000512094.5
ENST00000632629.1
nephrocystin 3
NPHP3-ACAD11 readthrough (NMD candidate)
chr5_-_143400716 0.01 ENST00000424646.6
ENST00000652686.1
nuclear receptor subfamily 3 group C member 1
chr1_-_113871665 0.01 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
protein tyrosine phosphatase non-receptor type 22
chr3_+_138621207 0.01 ENST00000464668.5
Fas apoptotic inhibitory molecule
chr15_+_92900189 0.01 ENST00000626874.2
ENST00000627622.1
ENST00000629346.2
ENST00000628375.2
ENST00000420239.7
ENST00000394196.9
chromodomain helicase DNA binding protein 2
chr1_-_151459471 0.01 ENST00000271715.7
pogo transposable element derived with ZNF domain
chr1_-_151459169 0.01 ENST00000368863.6
ENST00000409503.5
ENST00000491586.5
ENST00000533351.5
pogo transposable element derived with ZNF domain
chr10_+_18260715 0.01 ENST00000615785.4
ENST00000617363.4
ENST00000396576.6
calcium voltage-gated channel auxiliary subunit beta 2
chr17_-_10469558 0.01 ENST00000255381.2
myosin heavy chain 4
chr5_-_58999885 0.01 ENST00000317118.12
phosphodiesterase 4D
chr3_+_136930469 0.01 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chrX_+_151397163 0.01 ENST00000330374.7
vacuolar ATPase assembly factor VMA21
chr3_-_142029108 0.01 ENST00000497579.5
transcription factor Dp-2
chr18_+_34978244 0.00 ENST00000436190.6
microtubule associated protein RP/EB family member 2
chr11_-_13495984 0.00 ENST00000282091.6
parathyroid hormone
chrX_+_47836877 0.00 ENST00000338637.13
ENST00000376954.6
zinc finger protein 81
chr20_-_31390483 0.00 ENST00000376315.2
defensin beta 119

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX6-3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.1 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.0 0.1 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0001674 female germ cell nucleus(GO:0001674)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)