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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NR1I3

Z-value: 0.63

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Transcription factors associated with NR1I3

Gene Symbol Gene ID Gene Info
ENSG00000143257.12 nuclear receptor subfamily 1 group I member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I3hg38_v1_chr1_-_161238196_1612382100.452.6e-01Click!

Activity profile of NR1I3 motif

Sorted Z-values of NR1I3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_43935807 0.64 ENST00000438616.3
artemin
chr15_+_43593054 0.51 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
creatine kinase, mitochondrial 1B
chr14_+_21057822 0.48 ENST00000308227.2
ribonuclease A family member 8
chr1_+_153357846 0.48 ENST00000368738.4
S100 calcium binding protein A9
chr1_+_14924100 0.32 ENST00000361144.9
kazrin, periplakin interacting protein
chr1_-_205321737 0.31 ENST00000367157.6
NUAK family kinase 2
chr3_-_116444983 0.21 ENST00000333617.8
limbic system associated membrane protein
chr10_-_88583304 0.20 ENST00000331772.9
renalase, FAD dependent amine oxidase
chr14_-_21536928 0.15 ENST00000613414.4
spalt like transcription factor 2
chr14_+_22508602 0.15 ENST00000390504.1
T cell receptor alpha joining 33
chr2_-_68952880 0.13 ENST00000481498.1
ENST00000328895.9
gastrokine 2
chr16_+_2988256 0.13 ENST00000573315.2
long intergenic non-protein coding RNA 514
chr17_-_35943707 0.12 ENST00000615905.5
lysozyme like 6
chr17_-_35943662 0.12 ENST00000618542.4
lysozyme like 6
chr2_-_68871382 0.12 ENST00000295379.2
bone morphogenetic protein 10
chr16_+_527698 0.11 ENST00000219611.7
ENST00000562370.5
ENST00000568988.5
calpain 15
chr18_-_21704763 0.09 ENST00000580981.5
ENST00000289119.7
abhydrolase domain containing 3, phospholipase
chr11_+_63369779 0.09 ENST00000279178.4
solute carrier family 22 member 9
chr8_-_108787563 0.08 ENST00000297459.4
transmembrane protein 74
chr14_-_77320855 0.08 ENST00000556394.2
ENST00000261534.9
protein O-mannosyltransferase 2
chr18_-_21703688 0.08 ENST00000584464.1
ENST00000578270.5
abhydrolase domain containing 3, phospholipase
chr15_+_73684731 0.08 ENST00000560995.5
CD276 molecule
chr16_-_46689145 0.08 ENST00000299138.12
VPS35 retromer complex component
chr9_+_5450503 0.08 ENST00000381573.8
ENST00000381577.4
CD274 molecule
chr1_-_23559490 0.07 ENST00000374561.6
inhibitor of DNA binding 3, HLH protein
chrX_+_48786578 0.07 ENST00000376670.9
GATA binding protein 1
chr14_-_77320813 0.07 ENST00000682467.1
protein O-mannosyltransferase 2
chr14_+_24130659 0.07 ENST00000267426.6
fat storage inducing transmembrane protein 1
chr11_-_57322197 0.06 ENST00000532437.1
tankyrase 1 binding protein 1
chrX_-_111412162 0.06 ENST00000637570.1
ENST00000356220.8
ENST00000636035.2
ENST00000637453.1
ENST00000635795.1
doublecortin
chr19_-_43802438 0.06 ENST00000377950.8
LY6/PLAUR domain containing 5
chr11_+_113908983 0.06 ENST00000537778.5
5-hydroxytryptamine receptor 3B
chr14_+_94026314 0.06 ENST00000203664.10
ENST00000553723.1
OTU deubiquitinase, ubiquitin aldehyde binding 2
chrX_+_129738942 0.06 ENST00000371106.4
X-prolyl aminopeptidase 2
chrX_+_70455093 0.06 ENST00000542398.1
discs large MAGUK scaffold protein 3
chr20_-_46513516 0.06 ENST00000347606.8
ENST00000625284.2
ENST00000457685.6
zinc finger protein 334
chr14_-_21536884 0.06 ENST00000546363.5
spalt like transcription factor 2
chr16_-_74985070 0.06 ENST00000616369.4
ENST00000262144.11
WD repeat domain 59
chr12_-_53335737 0.06 ENST00000303846.3
Sp7 transcription factor
chr4_-_81215185 0.05 ENST00000264399.6
protein kinase cGMP-dependent 2
chr3_-_71753582 0.05 ENST00000295612.7
eukaryotic translation initiation factor 4E family member 3
chr10_-_73808616 0.05 ENST00000299641.8
N-deacetylase and N-sulfotransferase 2
chrX_-_15600953 0.05 ENST00000679212.1
ENST00000679278.1
ENST00000678046.1
ENST00000252519.8
angiotensin I converting enzyme 2
chr20_-_45378305 0.05 ENST00000372726.5
TP53 target 5
chr14_-_77320741 0.05 ENST00000682795.1
ENST00000682247.1
protein O-mannosyltransferase 2
chr6_+_108166015 0.05 ENST00000368986.9
nuclear receptor subfamily 2 group E member 1
chr4_-_81214960 0.05 ENST00000395578.3
ENST00000628926.1
protein kinase cGMP-dependent 2
chr19_+_676385 0.05 ENST00000166139.9
follistatin like 3
chr2_-_227164194 0.05 ENST00000396625.5
collagen type IV alpha 4 chain
chr11_-_47848467 0.04 ENST00000378460.6
nucleoporin 160
chr6_+_32439866 0.04 ENST00000374982.5
ENST00000395388.7
major histocompatibility complex, class II, DR alpha
chr19_-_45792755 0.04 ENST00000377735.7
ENST00000270223.7
DM1 locus, WD repeat containing
chr11_-_47848313 0.04 ENST00000530326.5
ENST00000528071.5
nucleoporin 160
chr13_-_94479671 0.04 ENST00000377028.10
ENST00000446125.1
dopachrome tautomerase
chr7_-_99784175 0.04 ENST00000651514.1
ENST00000336411.7
ENST00000415003.1
ENST00000354593.6
cytochrome P450 family 3 subfamily A member 4
chr2_+_219597838 0.04 ENST00000456909.6
serine/threonine kinase 11 interacting protein
chr3_+_122384167 0.04 ENST00000232125.9
ENST00000477892.5
ENST00000469967.1
family with sequence similarity 162 member A
chr12_-_118372883 0.04 ENST00000542532.5
ENST00000392533.8
TAO kinase 3
chr6_-_31541937 0.04 ENST00000456662.5
ENST00000431908.5
ENST00000456976.5
ENST00000428450.5
ENST00000418897.5
ENST00000396172.6
ENST00000419020.1
ENST00000428098.5
DExD-box helicase 39B
chr2_-_73269483 0.03 ENST00000295133.9
F-box protein 41
chr18_-_23586422 0.03 ENST00000269228.10
NPC intracellular cholesterol transporter 1
chr6_-_34146080 0.03 ENST00000538487.7
ENST00000374181.8
glutamate metabotropic receptor 4
chr12_+_100200779 0.03 ENST00000188312.7
ENST00000546902.5
ENST00000552376.5
ENST00000551617.1
actin related protein 6
chr3_-_116445458 0.03 ENST00000490035.7
limbic system associated membrane protein
chr1_+_43337803 0.03 ENST00000372470.9
ENST00000413998.7
MPL proto-oncogene, thrombopoietin receptor
chr8_-_52714414 0.03 ENST00000435644.6
ENST00000518710.5
ENST00000025008.10
ENST00000517963.1
RB1 inducible coiled-coil 1
chr9_+_37486006 0.03 ENST00000377792.3
RNA polymerase I subunit E
chr10_-_49188380 0.03 ENST00000374153.7
ENST00000374148.1
ENST00000374151.7
transmembrane protein 273
chr12_+_53423849 0.03 ENST00000257863.9
ENST00000550311.5
ENST00000379791.7
anti-Mullerian hormone receptor type 2
chr10_+_133160401 0.03 ENST00000684739.1
ENST00000682765.1
ENST00000683144.1
ENST00000683259.1
ENST00000682399.1
ENST00000368571.3
kinase non-catalytic C-lobe domain containing 1
chr6_-_43528867 0.03 ENST00000455285.2
exportin 5
chr8_+_11494367 0.03 ENST00000259089.9
ENST00000529894.1
BLK proto-oncogene, Src family tyrosine kinase
chr6_+_33454543 0.03 ENST00000621915.1
ENST00000395064.3
zinc finger and BTB domain containing 9
chr19_-_48637338 0.03 ENST00000601104.1
ENST00000222122.10
D-box binding PAR bZIP transcription factor
chr16_+_30699155 0.02 ENST00000262518.9
Snf2 related CREBBP activator protein
chr7_-_99784248 0.02 ENST00000652018.1
cytochrome P450 family 3 subfamily A member 4
chr1_+_40817190 0.02 ENST00000443478.3
potassium voltage-gated channel subfamily Q member 4
chr2_-_127884860 0.02 ENST00000393001.1
AMMECR1 like
chr2_-_86563382 0.02 ENST00000263856.9
charged multivesicular body protein 3
chr7_-_99735093 0.02 ENST00000611620.4
ENST00000620220.6
ENST00000336374.4
CYP3A7-CYP3A51P readthrough
cytochrome P450 family 3 subfamily A member 7
chr15_+_84980440 0.02 ENST00000310298.8
ENST00000557957.5
phosphodiesterase 8A
chr12_+_57604598 0.02 ENST00000548804.5
ENST00000550596.5
ENST00000551835.5
ENST00000549583.5
deltex E3 ubiquitin ligase 3
chr12_+_53380639 0.01 ENST00000426431.2
Sp1 transcription factor
chr6_-_127459364 0.01 ENST00000487331.2
ENST00000483725.8
KIAA0408
chr16_+_67873036 0.01 ENST00000358933.10
enhancer of mRNA decapping 4
chr14_+_77320996 0.01 ENST00000361389.8
ENST00000554279.5
ENST00000557639.5
ENST00000349555.7
ENST00000216465.10
ENST00000556627.5
ENST00000557053.5
glutathione S-transferase zeta 1
chr9_+_131125973 0.01 ENST00000651639.1
ENST00000451030.5
ENST00000531584.1
nucleoporin 214
chr6_+_70566892 0.01 ENST00000370474.4
succinate dehydrogenase complex assembly factor 4
chr1_+_56854764 0.01 ENST00000361249.4
complement C8 alpha chain
chr10_+_102503956 0.01 ENST00000369902.8
SUFU negative regulator of hedgehog signaling
chr1_-_225428813 0.01 ENST00000338179.6
ENST00000425080.1
lamin B receptor
chr6_+_96521796 0.01 ENST00000369278.5
UFM1 specific ligase 1
chr10_+_18400562 0.01 ENST00000377315.5
ENST00000650685.1
calcium voltage-gated channel auxiliary subunit beta 2
chr16_-_16223467 0.01 ENST00000575728.1
ENST00000574094.6
ENST00000205557.12
ATP binding cassette subfamily C member 6
chr3_-_58433810 0.01 ENST00000474765.1
ENST00000485460.5
ENST00000302746.11
ENST00000383714.8
pyruvate dehydrogenase E1 subunit beta
chr19_+_54200849 0.01 ENST00000626547.2
ENST00000302907.9
ENST00000391752.5
ENST00000402367.5
ENST00000391751.7
ribosomal protein S9
chr19_+_54201122 0.00 ENST00000391753.6
ENST00000441429.1
ribosomal protein S9
chr10_-_80172839 0.00 ENST00000265447.8
annexin A11
chr19_-_7497447 0.00 ENST00000593942.5
peroxisomal biogenesis factor 11 gamma
chr6_-_119149124 0.00 ENST00000368475.8
family with sequence similarity 184 member A
chr2_-_86563349 0.00 ENST00000409727.5
charged multivesicular body protein 3
chr2_+_70087468 0.00 ENST00000303577.7
poly(rC) binding protein 1
chr11_-_47848539 0.00 ENST00000526870.1
nucleoporin 160
chr19_+_58408633 0.00 ENST00000306910.9
ENST00000598901.1
ENST00000593920.5
ENST00000596281.1
zinc finger protein 584
chr4_+_37244735 0.00 ENST00000309447.6
NACHT and WD repeat domain containing 2
chr9_-_72953047 0.00 ENST00000297785.8
ENST00000376939.5
aldehyde dehydrogenase 1 family member A1
chr10_-_72088972 0.00 ENST00000317376.8
ENST00000412663.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0061146 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.1 0.5 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.5 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.1 GO:1903181 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.0 0.1 GO:0030221 basophil differentiation(GO:0030221)
0.0 0.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.0 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.2 GO:1902074 response to salt(GO:1902074)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling