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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NR2E1

Z-value: 1.12

Motif logo

Transcription factors associated with NR2E1

Gene Symbol Gene ID Gene Info
ENSG00000112333.12 nuclear receptor subfamily 2 group E member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2E1hg38_v1_chr6_+_108166015_108166034-0.068.8e-01Click!

Activity profile of NR2E1 motif

Sorted Z-values of NR2E1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91178520 1.03 ENST00000425043.5
ENST00000420120.6
ENST00000441303.6
ENST00000456569.2
decorin
chr12_+_55681647 0.93 ENST00000614691.1
methyltransferase like 7B
chr12_+_55681711 0.93 ENST00000394252.4
methyltransferase like 7B
chr8_-_121641424 0.81 ENST00000303924.5
hyaluronan synthase 2
chr1_+_170664121 0.81 ENST00000239461.11
paired related homeobox 1
chr12_-_91153149 0.81 ENST00000550758.1
decorin
chr5_-_9546066 0.71 ENST00000382496.10
ENST00000652226.1
semaphorin 5A
chr5_-_151157722 0.58 ENST00000517486.5
ENST00000377751.9
ENST00000521512.5
ENST00000517757.5
ENST00000354546.10
annexin A6
chr3_+_12351493 0.58 ENST00000683699.1
peroxisome proliferator activated receptor gamma
chr2_-_157444044 0.58 ENST00000264192.8
cytohesin 1 interacting protein
chr1_+_170663917 0.58 ENST00000497230.2
paired related homeobox 1
chr12_-_55842950 0.57 ENST00000548629.5
matrix metallopeptidase 19
chr17_-_68955332 0.57 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr5_-_111756245 0.55 ENST00000447165.6
neuronal regeneration related protein
chr11_-_70717994 0.55 ENST00000659264.1
SH3 and multiple ankyrin repeat domains 2
chr3_-_112638097 0.55 ENST00000461431.1
coiled-coil domain containing 80
chr10_-_21174187 0.52 ENST00000417816.2
nebulette
chr10_+_122560639 0.52 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
deleted in malignant brain tumors 1
chr8_+_103372388 0.51 ENST00000520337.1
collagen triple helix repeat containing 1
chr3_+_12351470 0.51 ENST00000287820.10
peroxisome proliferator activated receptor gamma
chr10_+_122560679 0.50 ENST00000657942.1
deleted in malignant brain tumors 1
chr5_-_91383310 0.49 ENST00000265138.4
arrestin domain containing 3
chr3_+_69739425 0.47 ENST00000352241.9
ENST00000642352.1
melanocyte inducing transcription factor
chr10_+_122560751 0.46 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
deleted in malignant brain tumors 1
chr4_-_156970903 0.45 ENST00000422544.2
platelet derived growth factor C
chr1_+_201739864 0.45 ENST00000367295.5
neuron navigator 1
chr8_+_76681208 0.41 ENST00000651372.2
zinc finger homeobox 4
chr1_+_185734362 0.38 ENST00000271588.9
hemicentin 1
chr5_+_76403266 0.38 ENST00000274364.11
IQ motif containing GTPase activating protein 2
chr16_-_73048104 0.38 ENST00000268489.10
zinc finger homeobox 3
chr3_+_69936583 0.37 ENST00000314557.10
ENST00000394351.9
melanocyte inducing transcription factor
chr9_-_92482350 0.37 ENST00000375543.2
asporin
chr12_-_89656093 0.36 ENST00000359142.7
ATPase plasma membrane Ca2+ transporting 1
chr4_+_80266639 0.35 ENST00000456523.3
ENST00000312465.12
fibroblast growth factor 5
chr12_-_89656051 0.35 ENST00000261173.6
ATPase plasma membrane Ca2+ transporting 1
chr3_+_69866217 0.34 ENST00000314589.10
melanocyte inducing transcription factor
chr3_+_141387616 0.33 ENST00000509883.5
zinc finger and BTB domain containing 38
chr6_-_152637351 0.33 ENST00000367255.10
spectrin repeat containing nuclear envelope protein 1
chr5_-_88883199 0.32 ENST00000514015.5
ENST00000503075.1
myocyte enhancer factor 2C
chr5_+_32711313 0.31 ENST00000265074.13
natriuretic peptide receptor 3
chr12_-_55842927 0.30 ENST00000322569.9
ENST00000409200.7
matrix metallopeptidase 19
chr9_-_16728165 0.29 ENST00000603713.5
ENST00000603313.5
basonuclin 2
chr1_-_85578345 0.28 ENST00000426972.8
dimethylarginine dimethylaminohydrolase 1
chr2_-_40430257 0.28 ENST00000408028.6
ENST00000332839.8
ENST00000406391.2
ENST00000405901.7
solute carrier family 8 member A1
chr22_-_33572227 0.28 ENST00000674780.1
LARGE xylosyl- and glucuronyltransferase 1
chr8_-_92017292 0.27 ENST00000521553.5
RUNX1 partner transcriptional co-repressor 1
chr1_-_158426237 0.26 ENST00000641042.1
olfactory receptor family 10 subfamily K member 2
chr9_-_92482499 0.25 ENST00000375544.7
asporin
chr7_-_13986439 0.25 ENST00000443608.5
ENST00000438956.5
ETS variant transcription factor 1
chr2_+_200308943 0.24 ENST00000619961.4
spermatogenesis associated serine rich 2 like
chr2_-_110534010 0.23 ENST00000437167.1
RANBP2 like and GRIP domain containing 6
chr19_+_18001117 0.23 ENST00000379656.7
arrestin domain containing 2
chr7_+_116526277 0.22 ENST00000393468.1
ENST00000393467.1
caveolin 1
chr1_+_158461574 0.22 ENST00000641432.1
ENST00000641460.1
ENST00000641535.1
ENST00000641971.1
olfactory receptor family 10 subfamily K member 1
chr17_-_8295342 0.22 ENST00000579192.5
ENST00000577745.2
solute carrier family 25 member 35
chr3_+_141387801 0.22 ENST00000514251.5
zinc finger and BTB domain containing 38
chr5_-_113434978 0.22 ENST00000390666.4
testis specific serine kinase 1B
chr10_-_24721866 0.22 ENST00000416305.1
ENST00000320481.10
Rho GTPase activating protein 21
chr12_-_81758665 0.22 ENST00000549325.5
ENST00000550584.6
PTPRF interacting protein alpha 2
chr5_-_160852200 0.21 ENST00000327245.10
ATPase phospholipid transporting 10B (putative)
chr1_-_68232539 0.21 ENST00000370976.7
ENST00000354777.6
Wnt ligand secretion mediator
chr2_+_87748087 0.21 ENST00000359481.9
plasminogen like B2
chr17_-_37542361 0.20 ENST00000614196.1
synergin gamma
chr6_+_31655888 0.20 ENST00000375916.4
apolipoprotein M
chr5_+_68292562 0.19 ENST00000523872.1
phosphoinositide-3-kinase regulatory subunit 1
chr1_-_48400826 0.19 ENST00000371841.1
spermatogenesis associated 6
chr8_-_17002327 0.19 ENST00000180166.6
fibroblast growth factor 20
chr8_-_38269157 0.19 ENST00000531823.5
ENST00000534339.5
ENST00000524616.5
ENST00000422581.6
ENST00000424479.7
ENST00000419686.2
phospholipid phosphatase 5
chrX_-_106038721 0.18 ENST00000372563.2
serpin family A member 7
chrX_-_66040057 0.18 ENST00000412866.2
V-set and immunoglobulin domain containing 4
chr20_-_31722854 0.18 ENST00000307677.5
BCL2 like 1
chr1_+_39215255 0.18 ENST00000671089.1
microtubule actin crosslinking factor 1
chr12_-_52553139 0.18 ENST00000267119.6
keratin 71
chr1_-_26913964 0.18 ENST00000254227.4
nuclear receptor subfamily 0 group B member 2
chr7_+_71132123 0.18 ENST00000333538.10
polypeptide N-acetylgalactosaminyltransferase 17
chrX_-_66040107 0.18 ENST00000455586.6
V-set and immunoglobulin domain containing 4
chr1_+_152878312 0.18 ENST00000368765.4
sperm mitochondria associated cysteine rich protein
chr14_+_51489112 0.18 ENST00000356218.8
FERM domain containing 6
chrX_+_47585212 0.17 ENST00000445623.1
TIMP metallopeptidase inhibitor 1
chrX_-_66040072 0.17 ENST00000374737.9
V-set and immunoglobulin domain containing 4
chr7_-_13986498 0.17 ENST00000420159.6
ENST00000399357.7
ENST00000403527.5
ETS variant transcription factor 1
chr20_-_31722949 0.17 ENST00000376055.9
BCL2 like 1
chr2_+_108621260 0.17 ENST00000409441.5
LIM zinc finger domain containing 1
chrX_-_143636094 0.16 ENST00000356928.2
SLIT and NTRK like family member 4
chrX_-_66033664 0.16 ENST00000427538.5
V-set and immunoglobulin domain containing 4
chr20_-_31722533 0.16 ENST00000677194.1
ENST00000434194.2
ENST00000376062.6
BCL2 like 1
chr6_+_106629594 0.16 ENST00000369044.1
glutaminyl-tRNA amidotransferase subunit QRSL1
chr5_+_137867852 0.16 ENST00000421631.6
ENST00000239926.9
myotilin
chr19_-_14062028 0.15 ENST00000669674.2
paralemmin 3
chr5_+_148394712 0.15 ENST00000513826.1
F-box protein 38
chr21_-_30372265 0.15 ENST00000399889.4
keratin associated protein 13-2
chr2_-_110473041 0.15 ENST00000632897.1
ENST00000413601.3
LIM zinc finger domain containing 4
chr3_-_71583683 0.14 ENST00000649631.1
ENST00000648718.1
forkhead box P1
chr16_+_7304219 0.14 ENST00000675562.1
RNA binding fox-1 homolog 1
chr1_-_68232514 0.14 ENST00000262348.9
ENST00000370973.2
ENST00000370971.1
Wnt ligand secretion mediator
chr12_-_81758641 0.14 ENST00000552948.5
ENST00000548586.5
PTPRF interacting protein alpha 2
chr5_+_119629552 0.14 ENST00000613773.4
ENST00000620555.4
ENST00000515256.5
ENST00000509264.1
family with sequence similarity 170 member A
chr2_+_176151543 0.14 ENST00000306324.4
homeobox D4
chr18_+_34710307 0.13 ENST00000679796.1
dystrobrevin alpha
chr7_+_116672357 0.13 ENST00000456159.1
MET proto-oncogene, receptor tyrosine kinase
chr3_-_18424533 0.13 ENST00000417717.6
SATB homeobox 1
chr5_+_172834225 0.13 ENST00000393784.8
endoplasmic reticulum-golgi intermediate compartment 1
chr11_-_111910790 0.13 ENST00000533280.6
crystallin alpha B
chr11_-_31812171 0.13 ENST00000639409.1
ENST00000640975.1
paired box 6
chr3_-_71583592 0.13 ENST00000650156.1
ENST00000649596.1
forkhead box P1
chr5_-_88883420 0.13 ENST00000437473.6
myocyte enhancer factor 2C
chr12_+_63844758 0.13 ENST00000631006.2
SLIT-ROBO Rho GTPase activating protein 1
chr16_+_3018390 0.12 ENST00000573001.5
TNF receptor superfamily member 12A
chr14_+_31025634 0.12 ENST00000673317.1
ENST00000556232.6
ENST00000542754.7
ENST00000554345.6
ENST00000334725.8
ENST00000554609.6
ENST00000313566.11
adaptor related protein complex 4 subunit sigma 1
chr3_+_128052390 0.12 ENST00000481210.5
ENST00000243253.8
SEC61 translocon subunit alpha 1
chr8_-_115492221 0.12 ENST00000518018.1
transcriptional repressor GATA binding 1
chr11_-_111923722 0.12 ENST00000527950.5
crystallin alpha B
chr15_-_43266857 0.12 ENST00000349114.8
ENST00000220420.10
transglutaminase 5
chr6_+_12290353 0.12 ENST00000379375.6
endothelin 1
chr8_+_23288081 0.11 ENST00000265806.12
ENST00000519952.6
ENST00000518840.6
R3H domain and coiled-coil containing 1
chr17_-_75262344 0.11 ENST00000579743.2
ENST00000578348.5
ENST00000582486.5
ENST00000582717.5
golgi associated, gamma adaptin ear containing, ARF binding protein 3
chr10_-_68407189 0.11 ENST00000388768.6
RUN and FYVE domain containing 2
chr22_-_41446777 0.11 ENST00000434408.1
ENST00000327492.4
transducer of ERBB2, 2
chr3_-_54928044 0.11 ENST00000273286.6
leucine rich repeats and transmembrane domains 1
chr12_+_119593758 0.11 ENST00000426426.3
transmembrane protein 233
chr2_-_189580773 0.11 ENST00000261024.7
solute carrier family 40 member 1
chr9_-_96302104 0.11 ENST00000375262.4
ENST00000650386.1
hydroxysteroid 17-beta dehydrogenase 3
chr11_-_111910830 0.11 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr1_+_61082398 0.11 ENST00000664149.1
nuclear factor I A
chr9_-_16727980 0.11 ENST00000418777.5
ENST00000468187.6
basonuclin 2
chrX_-_54798253 0.11 ENST00000218436.7
inter-alpha-trypsin inhibitor heavy chain family member 6
chr14_+_61697622 0.11 ENST00000539097.2
hypoxia inducible factor 1 subunit alpha
chr1_-_162412117 0.10 ENST00000367929.3
SH2 domain containing 1B
chr5_-_102296260 0.10 ENST00000310954.7
solute carrier organic anion transporter family member 4C1
chr5_-_143400716 0.10 ENST00000424646.6
ENST00000652686.1
nuclear receptor subfamily 3 group C member 1
chr1_+_150257247 0.10 ENST00000647854.1
carbonic anhydrase 14
chr10_-_68407242 0.10 ENST00000399200.7
ENST00000602465.6
ENST00000454950.6
RUN and FYVE domain containing 2
chr19_-_45424364 0.10 ENST00000589165.5
ERCC excision repair 1, endonuclease non-catalytic subunit
chr17_+_29568591 0.10 ENST00000581411.6
ENST00000301057.8
tumor protein p53 inducible protein 13
chr3_-_115147237 0.10 ENST00000357258.8
zinc finger and BTB domain containing 20
chr11_-_63015804 0.10 ENST00000535878.5
ENST00000545207.5
solute carrier family 22 member 8
chrX_+_38006551 0.10 ENST00000297875.7
synaptotagmin like 5
chr4_-_121164314 0.10 ENST00000057513.8
TNFAIP3 interacting protein 3
chr3_-_115147277 0.10 ENST00000675478.1
zinc finger and BTB domain containing 20
chr19_+_39268394 0.09 ENST00000331982.6
interferon lambda 2
chr16_+_47461314 0.09 ENST00000299167.12
ENST00000323584.10
ENST00000563376.5
phosphorylase kinase regulatory subunit beta
chr12_+_53461015 0.09 ENST00000553064.6
ENST00000547859.2
poly(rC) binding protein 2
chr12_+_56230652 0.09 ENST00000266980.8
ENST00000437277.1
solute carrier family 39 member 5
chr1_+_150257764 0.09 ENST00000369111.9
carbonic anhydrase 14
chr2_-_87021844 0.09 ENST00000355705.4
ENST00000409310.6
plasminogen like B1
chr3_+_69936629 0.09 ENST00000394348.2
ENST00000531774.1
melanocyte inducing transcription factor
chr5_-_73448769 0.09 ENST00000615637.3
forkhead box D1
chr11_-_62709493 0.09 ENST00000405837.5
ENST00000531524.5
ENST00000524862.6
ENST00000679883.1
BSCL2 lipid droplet biogenesis associated, seipin
chr6_+_52423680 0.09 ENST00000538167.2
EF-hand domain containing 1
chr7_+_116672187 0.09 ENST00000318493.11
ENST00000397752.8
MET proto-oncogene, receptor tyrosine kinase
chr12_-_119803383 0.09 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
citron rho-interacting serine/threonine kinase
chr19_+_11436044 0.09 ENST00000589838.5
protein kinase C substrate 80K-H
chr7_+_143132069 0.09 ENST00000291009.4
prolactin induced protein
chr3_+_101827982 0.08 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKB inhibitor zeta
chrX_-_48003949 0.08 ENST00000396965.5
ENST00000376943.8
zinc finger protein 182
chr11_-_6006946 0.08 ENST00000641156.1
ENST00000641835.1
olfactory receptor family 56 subfamily A member 4
chr5_+_32711723 0.08 ENST00000415167.2
natriuretic peptide receptor 3
chr20_+_11892493 0.08 ENST00000422390.5
ENST00000618918.4
BTB domain containing 3
chr1_+_61082702 0.08 ENST00000485903.6
ENST00000371185.6
ENST00000371184.6
nuclear factor I A
chr18_+_74597850 0.08 ENST00000582337.5
ENST00000299687.10
zinc finger protein 407
chr4_-_40630588 0.08 ENST00000514014.1
RNA binding motif protein 47
chr9_+_4662281 0.08 ENST00000381883.5
phospholipid phosphatase 6
chr17_+_7630094 0.08 ENST00000441599.6
ENST00000380450.9
ENST00000416273.7
ENST00000575903.5
ENST00000571153.5
ENST00000575618.5
ENST00000576152.1
ENST00000576830.5
sex hormone binding globulin
chr20_+_54475647 0.08 ENST00000395939.5
docking protein 5
chr7_-_108240049 0.08 ENST00000379022.8
neuronal cell adhesion molecule
chr20_-_38033424 0.08 ENST00000373447.8
ENST00000373448.6
TELO2 interacting protein 1
chr7_-_5959083 0.08 ENST00000539903.5
radial spoke head 10 homolog B
chr10_-_72088972 0.08 ENST00000317376.8
ENST00000412663.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr20_+_44531817 0.08 ENST00000372889.5
ENST00000372887.5
cAMP-dependent protein kinase inhibitor gamma
chr16_+_47461290 0.08 ENST00000566044.5
phosphorylase kinase regulatory subunit beta
chr9_-_92404559 0.08 ENST00000262551.8
ENST00000375561.10
osteoglycin
chr6_+_45422485 0.08 ENST00000359524.7
RUNX family transcription factor 2
chr7_+_134986483 0.08 ENST00000436302.6
ENST00000435976.6
ENST00000455283.2
ATP/GTP binding protein like 3
chr17_+_59197553 0.07 ENST00000582004.1
ENST00000577660.1
proline rich 11
novel protein
chr5_+_179699003 0.07 ENST00000681733.1
ENST00000680006.1
ENST00000680013.1
ENST00000681076.1
ENST00000681168.1
calnexin
chr12_+_75391078 0.07 ENST00000550916.6
ENST00000378692.7
ENST00000320460.8
ENST00000547164.1
GLIPR1 like 2
chr7_-_113919000 0.07 ENST00000284601.4
protein phosphatase 1 regulatory subunit 3A
chr3_-_169146595 0.07 ENST00000468789.5
MDS1 and EVI1 complex locus
chr1_+_163321890 0.07 ENST00000450453.6
ENST00000524800.5
ENST00000442820.5
ENST00000367900.7
NUF2 component of NDC80 kinetochore complex
chr8_+_79611727 0.07 ENST00000518491.1
stathmin 2
chr15_+_30903849 0.07 ENST00000561594.5
ENST00000658773.1
ENST00000657391.1
ENST00000656435.1
FANCD2 and FANCI associated nuclease 1
chr11_-_107565717 0.07 ENST00000428149.7
ENST00000429370.5
ENST00000417449.6
alkB homolog 8, tRNA methyltransferase
chr5_+_177600104 0.07 ENST00000029410.10
ENST00000510761.1
ENST00000505468.1
beta-1,4-galactosyltransferase 7
chr22_+_25069819 0.07 ENST00000401395.1
KIAA1671
chr14_+_93185304 0.07 ENST00000415050.3
transmembrane protein 251
chr4_-_110198579 0.07 ENST00000302274.8
ELOVL fatty acid elongase 6
chr12_-_57742120 0.07 ENST00000257897.7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr5_-_11588842 0.07 ENST00000503622.5
catenin delta 2
chr10_+_17752185 0.07 ENST00000377495.2
transmembrane protein 236
chr9_+_21409116 0.07 ENST00000380205.2
interferon alpha 8
chr15_+_30903877 0.07 ENST00000670849.1
ENST00000561607.6
ENST00000565466.5
ENST00000664837.1
ENST00000362065.9
ENST00000666143.1
FANCD2 and FANCI associated nuclease 1
chr8_+_24440930 0.07 ENST00000441335.6
ENST00000175238.10
ENST00000380789.5
ADAM metallopeptidase domain 7
chr11_+_121129964 0.07 ENST00000645008.1
tectorin alpha
chr3_-_71360753 0.07 ENST00000648783.1
forkhead box P1
chr1_-_154183199 0.06 ENST00000323144.12
ENST00000330188.13
ENST00000328159.9
ENST00000611659.4
tropomyosin 3
chr17_-_75979117 0.06 ENST00000301608.8
ENST00000293217.10
ENST00000588176.5
acyl-CoA oxidase 1
chr5_+_179698906 0.06 ENST00000452673.6
ENST00000680614.1
ENST00000680812.1
ENST00000681265.1
ENST00000680894.1
ENST00000681894.1
ENST00000679642.1
ENST00000680827.1
ENST00000680984.1
ENST00000680042.1
ENST00000681476.1
ENST00000681072.1
ENST00000247461.9
ENST00000502673.6
ENST00000513246.6
ENST00000680618.1
ENST00000680092.1
ENST00000506654.6
calnexin
chr9_-_89178810 0.06 ENST00000375835.9
SHC adaptor protein 3
chr17_-_42681840 0.06 ENST00000332438.4
C-C motif chemokine receptor 10
chr4_-_110198650 0.06 ENST00000394607.7
ELOVL fatty acid elongase 6

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2E1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 1.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 1.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.6 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 1.4 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.5 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 1.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.7 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 0.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.9 GO:0001554 luteolysis(GO:0001554)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.5 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.5 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.7 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1 0.5 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.2 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.2 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:1902823 negative regulation of late endosome to lysosome transport(GO:1902823)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.6 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.3 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 1.3 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.4 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.4 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.1 GO:0072076 nephrogenic mesenchyme development(GO:0072076) pattern specification involved in metanephros development(GO:0072268)
0.0 0.0 GO:0061055 myotome development(GO:0061055)
0.0 0.2 GO:1901164 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.6 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.3 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:0043586 tongue development(GO:0043586)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.1 GO:1902081 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.0 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.6 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.0 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.0 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.2 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.6 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0035061 perichromatin fibrils(GO:0005726) interchromatin granule(GO:0035061)
0.0 0.0 GO:1990075 stereocilia coupling link(GO:0002139) periciliary membrane compartment(GO:1990075)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0035375 zymogen binding(GO:0035375)
0.2 0.7 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 0.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.2 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 1.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0050567 amidase activity(GO:0004040) glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 1.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 2.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 3.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis