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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NR4A2

Z-value: 0.69

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Transcription factors associated with NR4A2

Gene Symbol Gene ID Gene Info
NR4A2
ENSG00000153234.15 nuclear receptor subfamily 4 group A member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A2hg38_v1_chr2_-_156332694_156332728-0.938.8e-04Click!

Activity profile of NR4A2 motif

Sorted Z-values of NR4A2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_43593054 0.77 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
CKMT1B
creatine kinase, mitochondrial 1B
chr15_+_43692886 0.66 ENST00000434505.5
ENST00000411750.5
CKMT1A
creatine kinase, mitochondrial 1A
chr20_+_59604527 0.66 ENST00000371015.6
PHACTR3
phosphatase and actin regulator 3
chr16_-_68236069 0.64 ENST00000473183.7
ENST00000565858.5
ESRP2
epithelial splicing regulatory protein 2
chr5_+_66828762 0.56 ENST00000490016.6
ENST00000403666.5
ENST00000450827.5
MAST4
microtubule associated serine/threonine kinase family member 4
chr17_-_2711633 0.41 ENST00000435359.5
CLUH
clustered mitochondria homolog
chr3_-_151316795 0.40 ENST00000260843.5
GPR87
G protein-coupled receptor 87
chr2_-_110115811 0.36 ENST00000272462.3
MALL
mal, T cell differentiation protein like
chr4_+_20253500 0.33 ENST00000622093.4
ENST00000273739.9
SLIT2
slit guidance ligand 2
chr10_-_75235917 0.32 ENST00000469299.1
ENST00000372538.8
COMTD1
catechol-O-methyltransferase domain containing 1
chr17_-_2711736 0.32 ENST00000651024.2
ENST00000576885.5
ENST00000574426.7
CLUH
clustered mitochondria homolog
chr10_+_79347491 0.31 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr2_+_219627394 0.31 ENST00000373760.6
SLC4A3
solute carrier family 4 member 3
chr4_-_102345469 0.30 ENST00000356736.5
ENST00000682932.1
SLC39A8
solute carrier family 39 member 8
chr11_-_66371728 0.29 ENST00000357440.7
ENST00000619145.4
SLC29A2
solute carrier family 29 member 2
chr17_-_29176752 0.28 ENST00000533112.5
MYO18A
myosin XVIIIA
chr7_-_81770122 0.27 ENST00000423064.7
HGF
hepatocyte growth factor
chr10_+_79347460 0.25 ENST00000225174.8
PPIF
peptidylprolyl isomerase F
chr16_-_58295019 0.24 ENST00000567164.6
ENST00000219301.8
ENST00000569727.1
PRSS54
serine protease 54
chr16_-_58294976 0.24 ENST00000543437.5
ENST00000569079.1
PRSS54
serine protease 54
chr1_-_115768702 0.23 ENST00000261448.6
CASQ2
calsequestrin 2
chr20_+_1895365 0.23 ENST00000358771.5
SIRPA
signal regulatory protein alpha
chr4_-_40515967 0.23 ENST00000381795.10
RBM47
RNA binding motif protein 47
chr1_+_9588860 0.22 ENST00000340381.11
ENST00000340305.9
TMEM201
transmembrane protein 201
chr16_+_85908988 0.22 ENST00000566369.1
IRF8
interferon regulatory factor 8
chr11_+_76860859 0.21 ENST00000679754.1
ENST00000534206.5
ENST00000680583.1
ENST00000532485.6
ENST00000526597.5
ENST00000533873.1
ACER3
alkaline ceramidase 3
chr4_-_138242325 0.21 ENST00000280612.9
SLC7A11
solute carrier family 7 member 11
chr21_+_41167774 0.20 ENST00000328735.10
ENST00000347667.5
BACE2
beta-secretase 2
chr8_+_144095054 0.19 ENST00000318911.5
CYC1
cytochrome c1
chr4_-_1856090 0.19 ENST00000302787.3
LETM1
leucine zipper and EF-hand containing transmembrane protein 1
chr7_+_73830988 0.19 ENST00000340958.4
CLDN4
claudin 4
chr8_-_130016414 0.19 ENST00000401979.6
ENST00000517654.5
ENST00000522361.1
ENST00000518167.5
CYRIB
CYFIP related Rac1 interactor B
chr7_+_48088596 0.18 ENST00000416681.5
ENST00000331803.8
ENST00000432131.5
UPP1
uridine phosphorylase 1
chr7_+_48089257 0.18 ENST00000436673.5
ENST00000395564.9
UPP1
uridine phosphorylase 1
chr21_+_41168142 0.18 ENST00000330333.11
BACE2
beta-secretase 2
chr8_-_130016395 0.18 ENST00000523509.5
CYRIB
CYFIP related Rac1 interactor B
chr14_-_21023954 0.18 ENST00000554094.5
NDRG2
NDRG family member 2
chr14_-_21024092 0.17 ENST00000554398.5
NDRG2
NDRG family member 2
chr12_+_132490140 0.17 ENST00000680143.1
FBRSL1
fibrosin like 1
chr11_-_9314564 0.17 ENST00000611268.4
ENST00000528080.6
ENST00000527813.5
ENST00000533723.1
TMEM41B
transmembrane protein 41B
chr9_-_39239174 0.17 ENST00000358144.6
CNTNAP3
contactin associated protein family member 3
chr1_+_236686454 0.17 ENST00000542672.6
ENST00000366578.6
ENST00000682015.1
ENST00000651275.1
ACTN2
actinin alpha 2
chr13_-_52011337 0.17 ENST00000400366.6
ENST00000400370.8
ENST00000634844.1
ENST00000673772.1
ENST00000418097.7
ENST00000242839.10
ENST00000344297.9
ENST00000448424.7
ATP7B
ATPase copper transporting beta
chr19_+_44891206 0.17 ENST00000405636.6
ENST00000252487.9
ENST00000592434.5
ENST00000589649.1
ENST00000426677.7
TOMM40
translocase of outer mitochondrial membrane 40
chr7_+_112450451 0.16 ENST00000429071.5
ENST00000403825.8
ENST00000675268.1
IFRD1
ENSG00000288634.1
interferon related developmental regulator 1
novel protein
chr7_-_73522278 0.15 ENST00000404251.1
ENST00000339594.9
BAZ1B
bromodomain adjacent to zinc finger domain 1B
chr8_-_130016622 0.15 ENST00000518283.5
ENST00000519110.5
CYRIB
CYFIP related Rac1 interactor B
chr8_+_22053543 0.14 ENST00000519850.5
ENST00000381470.7
DMTN
dematin actin binding protein
chr8_+_144358974 0.14 ENST00000526891.2
SLC52A2
solute carrier family 52 member 2
chr18_-_12377200 0.14 ENST00000269143.8
AFG3L2
AFG3 like matrix AAA peptidase subunit 2
chr9_-_114682172 0.14 ENST00000436752.3
TEX48
testis expressed 48
chr11_+_45805108 0.14 ENST00000530471.1
ENST00000314134.4
SLC35C1
solute carrier family 35 member C1
chr9_-_114682061 0.13 ENST00000612244.5
TEX48
testis expressed 48
chr10_-_100081854 0.13 ENST00000370418.8
CPN1
carboxypeptidase N subunit 1
chr1_+_174447944 0.13 ENST00000367685.5
GPR52
G protein-coupled receptor 52
chr14_+_21030201 0.13 ENST00000321760.11
ENST00000460647.6
ENST00000530140.6
ENST00000472458.5
TPPP2
tubulin polymerization promoting protein family member 2
chrX_+_154411519 0.13 ENST00000612460.5
ENST00000601016.6
ENST00000613002.4
ENST00000475699.6
ENST00000612012.5
ENST00000369776.8
ENST00000439735.2
ENST00000616020.5
ENST00000652358.1
ENST00000652390.1
TAZ
tafazzin
chr7_-_126533850 0.13 ENST00000444921.3
GRM8
glutamate metabotropic receptor 8
chr8_-_143944737 0.13 ENST00000398774.6
PLEC
plectin
chr15_+_59438149 0.12 ENST00000288228.10
ENST00000559628.5
ENST00000557914.5
ENST00000560474.5
FAM81A
family with sequence similarity 81 member A
chr7_+_39623886 0.12 ENST00000436179.1
RALA
RAS like proto-oncogene A
chr8_-_18083184 0.12 ENST00000636269.1
ASAH1
N-acylsphingosine amidohydrolase 1
chr1_-_157138474 0.12 ENST00000326786.4
ETV3
ETS variant transcription factor 3
chr4_-_151015263 0.12 ENST00000510413.5
ENST00000507224.5
ENST00000651943.2
LRBA
LPS responsive beige-like anchor protein
chr11_+_73950985 0.12 ENST00000339764.6
DNAJB13
DnaJ heat shock protein family (Hsp40) member B13
chr7_+_23598144 0.11 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr7_+_37920602 0.11 ENST00000199448.9
ENST00000423717.1
EPDR1
ependymin related 1
chr6_-_106629472 0.11 ENST00000369063.8
RTN4IP1
reticulon 4 interacting protein 1
chr19_+_1407731 0.11 ENST00000592453.2
DAZAP1
DAZ associated protein 1
chr17_-_676348 0.11 ENST00000681510.1
ENST00000679680.1
VPS53
VPS53 subunit of GARP complex
chr1_+_6034677 0.11 ENST00000668559.1
KCNAB2
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr4_-_151015713 0.11 ENST00000357115.9
LRBA
LPS responsive beige-like anchor protein
chr4_-_110198650 0.11 ENST00000394607.7
ELOVL6
ELOVL fatty acid elongase 6
chr4_+_80197493 0.11 ENST00000415738.3
PRDM8
PR/SET domain 8
chr22_-_37484505 0.11 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_-_110198579 0.10 ENST00000302274.8
ELOVL6
ELOVL fatty acid elongase 6
chr22_-_29388530 0.10 ENST00000357586.7
ENST00000432560.6
ENST00000405198.6
ENST00000317368.11
AP1B1
adaptor related protein complex 1 subunit beta 1
chr1_+_6034980 0.10 ENST00000378092.6
ENST00000472700.7
KCNAB2
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr2_+_119431846 0.10 ENST00000306406.5
TMEM37
transmembrane protein 37
chr17_+_7630094 0.10 ENST00000441599.6
ENST00000380450.9
ENST00000416273.7
ENST00000575903.5
ENST00000571153.5
ENST00000575618.5
ENST00000576152.1
ENST00000576830.5
SHBG
sex hormone binding globulin
chr10_-_49762335 0.09 ENST00000419399.4
ENST00000432695.2
OGDHL
oxoglutarate dehydrogenase L
chr1_-_225941383 0.09 ENST00000420304.6
LEFTY2
left-right determination factor 2
chr5_+_218241 0.09 ENST00000617470.4
ENST00000504309.5
ENST00000510361.5
ENST00000264932.11
SDHA
succinate dehydrogenase complex flavoprotein subunit A
chr19_-_15125751 0.09 ENST00000263383.8
ILVBL
ilvB acetolactate synthase like
chr1_+_212565334 0.09 ENST00000366981.8
ENST00000366987.6
ATF3
activating transcription factor 3
chr16_+_56730099 0.09 ENST00000563858.5
ENST00000566315.5
ENST00000308159.10
ENST00000569842.5
ENST00000569863.5
NUP93
nucleoporin 93
chr6_+_106629594 0.09 ENST00000369044.1
QRSL1
glutaminyl-tRNA amidotransferase subunit QRSL1
chr4_-_98929092 0.09 ENST00000280892.10
ENST00000511644.5
ENST00000504432.5
ENST00000450253.7
ENST00000505992.1
EIF4E
eukaryotic translation initiation factor 4E
chr13_-_113864062 0.08 ENST00000327773.7
GAS6
growth arrest specific 6
chr1_+_43337803 0.08 ENST00000372470.9
ENST00000413998.7
MPL
MPL proto-oncogene, thrombopoietin receptor
chr4_+_24795560 0.08 ENST00000382120.4
SOD3
superoxide dismutase 3
chr3_-_42701513 0.08 ENST00000310417.9
HHATL
hedgehog acyltransferase like
chr12_+_10010627 0.08 ENST00000338896.11
ENST00000396502.5
CLEC12B
C-type lectin domain family 12 member B
chr15_+_64911869 0.08 ENST00000319580.13
ENST00000496660.5
ANKDD1A
ankyrin repeat and death domain containing 1A
chr20_+_19758245 0.08 ENST00000255006.12
RIN2
Ras and Rab interactor 2
chr4_+_41612892 0.08 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIMCH1
LIM and calponin homology domains 1
chr3_-_197298558 0.08 ENST00000656944.1
ENST00000346964.6
ENST00000448528.6
ENST00000655488.1
ENST00000357674.9
ENST00000667157.1
ENST00000661336.1
ENST00000654737.1
ENST00000659716.1
ENST00000657381.1
DLG1
discs large MAGUK scaffold protein 1
chr13_-_103066411 0.08 ENST00000245312.5
SLC10A2
solute carrier family 10 member 2
chr19_-_55063170 0.08 ENST00000610356.4
RDH13
retinol dehydrogenase 13
chr10_-_49942027 0.08 ENST00000616448.2
PARG
poly(ADP-ribose) glycohydrolase
chr3_-_113746218 0.08 ENST00000497255.1
ENST00000240922.8
ENST00000478020.1
ENST00000493900.5
NAA50
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr7_+_39623547 0.08 ENST00000005257.7
RALA
RAS like proto-oncogene A
chr3_+_9703826 0.08 ENST00000613455.4
ENST00000383831.7
ENST00000383832.8
CPNE9
copine family member 9
chr12_+_120438107 0.08 ENST00000229379.3
ENST00000551806.1
COX6A1
ENSG00000111780.8
cytochrome c oxidase subunit 6A1
novel protein
chr2_+_102761963 0.08 ENST00000640575.2
ENST00000412401.3
TMEM182
transmembrane protein 182
chr1_-_225941212 0.08 ENST00000366820.10
LEFTY2
left-right determination factor 2
chr16_-_81198766 0.07 ENST00000526632.5
PKD1L2
polycystin 1 like 2 (gene/pseudogene)
chr5_-_132011811 0.07 ENST00000379255.5
ENST00000430403.5
ENST00000357096.5
ACSL6
acyl-CoA synthetase long chain family member 6
chr6_-_39322540 0.07 ENST00000425054.6
ENST00000373227.8
ENST00000373229.9
KCNK16
potassium two pore domain channel subfamily K member 16
chr3_+_57556244 0.07 ENST00000311180.9
ENST00000487257.1
PDE12
phosphodiesterase 12
chr19_-_56121223 0.07 ENST00000587279.1
ENST00000610935.2
ZNF787
zinc finger protein 787
chr19_-_7943648 0.07 ENST00000597926.1
ENST00000270538.8
TIMM44
translocase of inner mitochondrial membrane 44
chr3_+_52779916 0.07 ENST00000537050.5
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr8_+_135457442 0.07 ENST00000355849.10
KHDRBS3
KH RNA binding domain containing, signal transduction associated 3
chr6_-_31660735 0.07 ENST00000375911.2
C6orf47
chromosome 6 open reading frame 47
chr17_-_58280928 0.07 ENST00000225275.4
MPO
myeloperoxidase
chr19_-_35563653 0.07 ENST00000262623.4
ATP4A
ATPase H+/K+ transporting subunit alpha
chr19_+_589873 0.07 ENST00000251287.3
HCN2
hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
chr1_-_205935822 0.07 ENST00000340781.8
SLC26A9
solute carrier family 26 member 9
chr11_+_3855629 0.07 ENST00000526596.2
ENST00000300737.8
ENST00000616714.4
STIM1
stromal interaction molecule 1
chr15_-_40828699 0.07 ENST00000299174.10
ENST00000427255.2
PPP1R14D
protein phosphatase 1 regulatory inhibitor subunit 14D
chr2_+_233718734 0.06 ENST00000373409.8
UGT1A4
UDP glucuronosyltransferase family 1 member A4
chr3_-_167734465 0.06 ENST00000487947.6
PDCD10
programmed cell death 10
chr19_+_1407653 0.06 ENST00000587079.5
DAZAP1
DAZ associated protein 1
chr2_-_197499826 0.06 ENST00000439605.2
ENST00000388968.8
ENST00000418022.2
HSPD1
heat shock protein family D (Hsp60) member 1
chr1_+_155209213 0.06 ENST00000609421.1
MTX1
metaxin 1
chr1_+_44674688 0.06 ENST00000418644.5
ENST00000458657.6
ENST00000535358.6
ENST00000441519.5
ENST00000445071.5
ARMH1
armadillo like helical domain containing 1
chr2_-_206159509 0.06 ENST00000423725.5
NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1
chr20_+_54475584 0.06 ENST00000262593.10
DOK5
docking protein 5
chrX_+_153517626 0.06 ENST00000263519.5
ATP2B3
ATPase plasma membrane Ca2+ transporting 3
chr7_+_112423137 0.06 ENST00000005558.8
ENST00000621379.4
IFRD1
interferon related developmental regulator 1
chr2_+_233712905 0.06 ENST00000373414.4
UGT1A5
UDP glucuronosyltransferase family 1 member A5
chrX_+_44873552 0.06 ENST00000683021.1
KDM6A
lysine demethylase 6A
chr3_-_167734510 0.06 ENST00000475915.6
ENST00000462725.6
ENST00000461494.5
PDCD10
programmed cell death 10
chr1_-_20661356 0.06 ENST00000602624.7
ENST00000464364.1
DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
chrX_+_44873169 0.06 ENST00000675577.1
ENST00000674867.1
ENST00000674586.1
ENST00000382899.9
ENST00000536777.6
ENST00000543216.6
ENST00000377967.9
ENST00000611820.5
KDM6A
lysine demethylase 6A
chr3_-_42702778 0.06 ENST00000457462.5
ENST00000441594.6
HHATL
hedgehog acyltransferase like
chr22_+_31122923 0.06 ENST00000620191.4
ENST00000412277.6
ENST00000412985.5
ENST00000331075.10
ENST00000420017.5
ENST00000400294.6
ENST00000405300.5
ENST00000404390.7
INPP5J
inositol polyphosphate-5-phosphatase J
chr2_+_219442023 0.06 ENST00000431523.5
ENST00000396698.5
SPEG
striated muscle enriched protein kinase
chr1_-_157138388 0.06 ENST00000368192.9
ETV3
ETS variant transcription factor 3
chr9_+_110668779 0.05 ENST00000416899.7
ENST00000374448.9
MUSK
muscle associated receptor tyrosine kinase
chr9_-_133479075 0.05 ENST00000414172.1
ENST00000371897.8
ENST00000371899.9
SLC2A6
solute carrier family 2 member 6
chrX_+_70452286 0.05 ENST00000374355.7
DLG3
discs large MAGUK scaffold protein 3
chr11_+_66857056 0.05 ENST00000309602.5
ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr19_-_49049111 0.05 ENST00000448456.4
CGB8
chorionic gonadotropin subunit beta 8
chr3_-_172711166 0.05 ENST00000538775.5
ENST00000543711.5
NCEH1
neutral cholesterol ester hydrolase 1
chr20_+_33168148 0.05 ENST00000354932.6
BPIFA2
BPI fold containing family A member 2
chr10_-_14838003 0.05 ENST00000465530.2
CDNF
cerebral dopamine neurotrophic factor
chr2_-_197499857 0.05 ENST00000428204.6
ENST00000678170.1
ENST00000676933.1
ENST00000678621.1
HSPD1
heat shock protein family D (Hsp60) member 1
chr12_-_69699331 0.05 ENST00000548658.1
ENST00000476098.5
BEST3
bestrophin 3
chr5_+_96936071 0.05 ENST00000231368.10
LNPEP
leucyl and cystinyl aminopeptidase
chr12_+_93569814 0.05 ENST00000340600.6
SOCS2
suppressor of cytokine signaling 2
chr17_+_81703356 0.05 ENST00000333676.8
ENST00000571730.1
MRPL12
ENSG00000262660.1
mitochondrial ribosomal protein L12
novel protein
chr5_-_150412743 0.05 ENST00000353334.11
ENST00000009530.12
ENST00000377795.7
CD74
CD74 molecule
chr12_-_108561157 0.05 ENST00000228284.8
ENST00000431469.6
ENST00000546815.6
SART3
spliceosome associated factor 3, U4/U6 recycling protein
chr19_+_1407517 0.05 ENST00000336761.10
ENST00000233078.9
ENST00000592522.5
DAZAP1
DAZ associated protein 1
chr10_-_126670686 0.05 ENST00000488181.3
C10orf90
chromosome 10 open reading frame 90
chr16_-_1884231 0.05 ENST00000563416.3
ENST00000633813.1
ENST00000470044.5
LINC00254
MEIOB
long intergenic non-protein coding RNA 254
meiosis specific with OB-fold
chr7_-_81770039 0.05 ENST00000222390.11
ENST00000453411.6
ENST00000457544.7
ENST00000444829.7
HGF
hepatocyte growth factor
chr10_-_48914232 0.05 ENST00000374160.7
LRRC18
leucine rich repeat containing 18
chr9_-_135961310 0.05 ENST00000371756.4
UBAC1
UBA domain containing 1
chr12_-_69699455 0.05 ENST00000266661.8
BEST3
bestrophin 3
chrY_-_13479938 0.05 ENST00000382893.2
ENST00000382896.9
ENST00000545955.6
UTY
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chr8_+_133191060 0.04 ENST00000519433.1
ENST00000517423.5
ENST00000220856.6
CCN4
cellular communication network factor 4
chr1_-_17054015 0.04 ENST00000375499.8
SDHB
succinate dehydrogenase complex iron sulfur subunit B
chr4_-_64409444 0.04 ENST00000381210.8
ENST00000507440.5
TECRL
trans-2,3-enoyl-CoA reductase like
chr20_+_48921701 0.04 ENST00000371917.5
ARFGEF2
ADP ribosylation factor guanine nucleotide exchange factor 2
chr10_+_96130027 0.04 ENST00000478086.5
ENST00000624776.3
ZNF518A
zinc finger protein 518A
chr12_-_114406133 0.04 ENST00000405440.7
TBX5
T-box transcription factor 5
chr9_+_110668854 0.04 ENST00000189978.10
ENST00000374440.7
MUSK
muscle associated receptor tyrosine kinase
chr11_-_790062 0.04 ENST00000330106.5
CEND1
cell cycle exit and neuronal differentiation 1
chr7_-_151736304 0.04 ENST00000492843.6
PRKAG2
protein kinase AMP-activated non-catalytic subunit gamma 2
chr22_+_49960760 0.04 ENST00000360612.5
PIM3
Pim-3 proto-oncogene, serine/threonine kinase
chr20_+_44715360 0.04 ENST00000190983.5
CCN5
cellular communication network factor 5
chr11_-_132943671 0.04 ENST00000331898.11
OPCML
opioid binding protein/cell adhesion molecule like
chr2_+_218270392 0.04 ENST00000248451.7
ENST00000273077.9
PNKD
PNKD metallo-beta-lactamase domain containing
chr3_+_113532508 0.04 ENST00000264852.9
SIDT1
SID1 transmembrane family member 1
chr11_+_78188871 0.04 ENST00000528910.5
ENST00000529308.6
USP35
ubiquitin specific peptidase 35
chr9_+_113221528 0.04 ENST00000374212.5
SLC31A1
solute carrier family 31 member 1
chr15_+_78149354 0.04 ENST00000558554.5
ENST00000557826.5
ENST00000561279.5
ENST00000299518.7
ENST00000559186.5
ENST00000560770.5
ENST00000559881.5
ENST00000559205.1
ENST00000629769.2
IDH3A
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
chr12_-_6606320 0.04 ENST00000642594.1
ENST00000644289.1
ENST00000645095.1
CHD4
chromodomain helicase DNA binding protein 4
chr3_-_45958572 0.04 ENST00000433878.5
FYCO1
FYVE and coiled-coil domain autophagy adaptor 1
chr10_+_96129707 0.04 ENST00000316045.9
ZNF518A
zinc finger protein 518A
chr12_-_16606795 0.04 ENST00000447609.5
LMO3
LIM domain only 3
chr1_-_201171545 0.04 ENST00000367333.6
TMEM9
transmembrane protein 9
chr7_+_45574358 0.04 ENST00000297323.12
ADCY1
adenylate cyclase 1
chr19_-_5622768 0.04 ENST00000252542.9
SAFB2
scaffold attachment factor B2
chr1_+_32292067 0.04 ENST00000373548.8
ENST00000428704.1
HDAC1
histone deacetylase 1
chr10_+_45972482 0.04 ENST00000580018.4
TIMM23
translocase of inner mitochondrial membrane 23
chr20_-_37527862 0.04 ENST00000373537.7
ENST00000445723.5
ENST00000414080.1
BLCAP
BLCAP apoptosis inducing factor
chr17_+_28744002 0.04 ENST00000618771.1
ENST00000262395.10
ENST00000422344.5
TRAF4
TNF receptor associated factor 4
chr15_-_42491105 0.04 ENST00000565380.5
ENST00000564754.7
ZNF106
zinc finger protein 106
chr16_-_87493013 0.04 ENST00000671377.2
ZCCHC14
zinc finger CCHC-type containing 14
chr2_+_219434825 0.04 ENST00000312358.12
SPEG
striated muscle enriched protein kinase
chr9_+_126805003 0.04 ENST00000449886.5
ENST00000450858.1
ENST00000373464.5
ZBTB43
zinc finger and BTB domain containing 43
chr4_-_73223082 0.03 ENST00000509867.6
ANKRD17
ankyrin repeat domain 17
chr6_+_106629560 0.03 ENST00000369046.8
QRSL1
glutaminyl-tRNA amidotransferase subunit QRSL1
chr2_+_233778330 0.03 ENST00000389758.3
MROH2A
maestro heat like repeat family member 2A
chr3_-_113746185 0.03 ENST00000616174.1
NAA50
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr4_-_121952014 0.03 ENST00000379645.8
TRPC3
transient receptor potential cation channel subfamily C member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.4 GO:0046108 uridine metabolic process(GO:0046108)
0.1 0.3 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.2 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.2 GO:0051695 actin filament uncapping(GO:0051695)
0.1 0.2 GO:0060003 copper ion export(GO:0060003)
0.0 0.7 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.0 0.7 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0097017 renal protein absorption(GO:0097017)
0.0 0.1 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.6 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.3 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.2 GO:0086029 Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.4 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.0 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.0 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.0 0.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.2 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.0 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.0 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.3 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 0.6 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.3 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.0 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.0 GO:0035434 copper ion transmembrane transport(GO:0035434)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.1 GO:0046696 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.7 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.2 GO:0031753 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 0.2 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.1 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0050567 amidase activity(GO:0004040) glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.3 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters