Project
avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)
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Results for NR5A2
Z-value: 0.96
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Transcription factors associated with NR5A2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NR5A2 | hg38_v1_chr1_+_200027702_200027716 | -0.71 | 4.7e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_+_59577463 Show fit | 1.34 |
ENST00000359926.7
|
phosphatase and actin regulator 3 |
|
| chr10_+_116427839 Show fit | 0.86 |
ENST00000369230.4
|
pancreatic lipase related protein 3 |
|
| chr20_+_59604527 Show fit | 0.82 |
ENST00000371015.6
|
phosphatase and actin regulator 3 |
|
| chr2_+_219627394 Show fit | 0.77 |
ENST00000373760.6
|
solute carrier family 4 member 3 |
|
| chr15_+_43593054 Show fit | 0.71 |
ENST00000453782.5
ENST00000300283.10 ENST00000437924.5 |
creatine kinase, mitochondrial 1B |
|
| chr15_+_43692886 Show fit | 0.69 |
ENST00000434505.5
ENST00000411750.5 |
creatine kinase, mitochondrial 1A |
|
| chr6_-_136526177 Show fit | 0.56 |
ENST00000617204.4
|
microtubule associated protein 7 |
|
| chr6_-_136525961 Show fit | 0.45 |
ENST00000438100.6
|
microtubule associated protein 7 |
|
| chr11_-_72785932 Show fit | 0.45 |
ENST00000539138.1
ENST00000542989.5 |
StAR related lipid transfer domain containing 10 |
|
| chr22_+_39994926 Show fit | 0.42 |
ENST00000333407.11
|
family with sequence similarity 83 member F |
Network of associatons between targets according to the STRING database.
First level regulatory network of NR5A2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.1 | 1.0 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.1 | 0.8 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.0 | 0.7 | GO:0008088 | axo-dendritic transport(GO:0008088) |
| 0.2 | 0.6 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 0.0 | 0.6 | GO:0048875 | chemical homeostasis within a tissue(GO:0048875) |
| 0.1 | 0.4 | GO:0009720 | detection of hormone stimulus(GO:0009720) |
| 0.1 | 0.4 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 0.1 | 0.4 | GO:0033159 | negative regulation of protein import into nucleus, translocation(GO:0033159) |
| 0.1 | 0.4 | GO:0006196 | AMP catabolic process(GO:0006196) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.8 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.0 | 0.5 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.0 | 0.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 0.4 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.1 | 0.3 | GO:0045259 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259) |
| 0.1 | 0.3 | GO:0034666 | integrin alpha2-beta1 complex(GO:0034666) |
| 0.1 | 0.3 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 0.0 | 0.3 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.0 | 0.2 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 1.5 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.1 | 1.0 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.0 | 0.9 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 0.9 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.1 | 0.7 | GO:0038064 | collagen receptor activity(GO:0038064) |
| 0.0 | 0.5 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.0 | 0.5 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.1 | 0.4 | GO:0005011 | macrophage colony-stimulating factor receptor activity(GO:0005011) |
| 0.1 | 0.4 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 0.3 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 0.1 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.5 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 0.5 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.0 | 0.4 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 0.4 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.3 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.0 | 0.3 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 0.2 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.0 | 0.1 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |