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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for OLIG2_NEUROD1_ATOH1

Z-value: 0.37

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Transcription factors associated with OLIG2_NEUROD1_ATOH1

Gene Symbol Gene ID Gene Info
ENSG00000205927.5 oligodendrocyte transcription factor 2
ENSG00000162992.5 neuronal differentiation 1
ENSG00000172238.6 atonal bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NEUROD1hg38_v1_chr2_-_181680490_181680525-0.743.7e-02Click!
OLIG2hg38_v1_chr21_+_33025927_330259420.314.5e-01Click!
ATOH1hg38_v1_chr4_+_93828746_938287580.265.3e-01Click!

Activity profile of OLIG2_NEUROD1_ATOH1 motif

Sorted Z-values of OLIG2_NEUROD1_ATOH1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_113292838 1.05 ENST00000672411.1
ENST00000673231.1
ankyrin 2
chr4_+_113292925 1.03 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ankyrin 2
chr8_-_134510182 0.99 ENST00000521673.5
zinc finger and AT-hook domain containing
chr4_+_113049616 0.76 ENST00000504454.5
ENST00000357077.9
ENST00000394537.7
ENST00000672779.1
ENST00000264366.10
ankyrin 2
chr19_-_38253238 0.70 ENST00000587515.5
protein phosphatase 1 regulatory inhibitor subunit 14A
chr12_+_4273751 0.66 ENST00000675880.1
ENST00000261254.8
cyclin D2
chr4_+_54229261 0.42 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chr17_+_41226648 0.40 ENST00000377721.3
keratin associated protein 9-2
chr22_+_44677077 0.33 ENST00000403581.5
proline rich 5
chr22_+_44677044 0.31 ENST00000006251.11
proline rich 5
chr13_+_87671354 0.30 ENST00000683689.1
SLIT and NTRK like family member 5
chrX_+_136197039 0.30 ENST00000370683.6
four and a half LIM domains 1
chr16_+_21704963 0.30 ENST00000388957.3
otoancorin
chr19_+_15949008 0.30 ENST00000322107.1
olfactory receptor family 10 subfamily H member 4
chr17_-_9791586 0.29 ENST00000571134.2
dehydrogenase/reductase 7C
chrX_+_136196750 0.29 ENST00000539015.5
four and a half LIM domains 1
chr11_+_18602969 0.28 ENST00000636011.1
ENST00000542172.1
SPTY2D1 opposite strand
chrX_+_136197020 0.28 ENST00000370676.7
four and a half LIM domains 1
chr17_-_79952007 0.25 ENST00000574241.6
TBC1 domain family member 16
chr3_-_52452828 0.25 ENST00000496590.1
troponin C1, slow skeletal and cardiac type
chr19_+_53867874 0.25 ENST00000448420.5
ENST00000439000.5
ENST00000391771.1
ENST00000391770.9
myeloid associated differentiation marker
chr12_+_4269771 0.22 ENST00000676411.1
cyclin D2
chr15_+_22094522 0.21 ENST00000328795.5
olfactory receptor family 4 subfamily N member 4
chr8_-_41665261 0.21 ENST00000522231.5
ENST00000314214.12
ENST00000348036.8
ENST00000522543.5
ankyrin 1
chr19_-_11339573 0.20 ENST00000222120.8
RAB3D, member RAS oncogene family
chr10_-_114684457 0.20 ENST00000392955.7
actin binding LIM protein 1
chr10_-_114684612 0.20 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr14_+_24115299 0.19 ENST00000559354.5
ENST00000560459.5
ENST00000559593.5
ENST00000396941.8
ENST00000396936.5
DDB1 and CUL4 associated factor 11
chr3_-_18438767 0.19 ENST00000454909.6
SATB homeobox 1
chr6_+_150143018 0.19 ENST00000361131.5
protein phosphatase 1 regulatory inhibitor subunit 14C
chr11_-_64166102 0.19 ENST00000255681.7
ENST00000675777.1
mono-ADP ribosylhydrolase 1
chr20_+_44355692 0.19 ENST00000316673.8
ENST00000609795.5
ENST00000457232.5
ENST00000609262.5
hepatocyte nuclear factor 4 alpha
chr19_+_40717091 0.18 ENST00000263370.3
inositol-trisphosphate 3-kinase C
chr17_+_7438267 0.18 ENST00000575235.5
fibroblast growth factor 11
chr15_+_88638947 0.18 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr11_+_57598184 0.18 ENST00000677625.1
ENST00000676670.1
serpin family G member 1
chr11_+_57597563 0.18 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
serpin family G member 1
chr7_+_76302665 0.18 ENST00000248553.7
ENST00000674638.1
ENST00000674547.1
ENST00000675226.1
ENST00000675538.1
ENST00000676231.1
ENST00000675134.1
ENST00000675906.1
ENST00000674650.1
heat shock protein family B (small) member 1
chr1_-_110064916 0.18 ENST00000649954.1
ALX homeobox 3
chr5_+_176810552 0.16 ENST00000329542.9
unc-5 netrin receptor A
chr21_+_29130630 0.16 ENST00000399926.5
ENST00000399928.6
MAP3K7 C-terminal like
chr12_+_26195313 0.16 ENST00000422622.3
sarcospan
chr19_+_17305801 0.16 ENST00000602206.1
ENST00000252602.2
mitochondrial ribosomal protein L34
chr9_+_113536497 0.16 ENST00000462143.5
regulator of G protein signaling 3
chr12_+_26195543 0.15 ENST00000242729.7
sarcospan
chr5_+_168291599 0.15 ENST00000265293.9
WW and C2 domain containing 1
chr10_-_60389833 0.15 ENST00000280772.7
ankyrin 3
chr17_-_58415628 0.15 ENST00000583753.5
ring finger protein 43
chr1_-_205422050 0.15 ENST00000367153.9
LEM domain containing 1
chr7_-_100479142 0.15 ENST00000300181.7
ENST00000393991.5
TSC22 domain family member 4
chr12_+_57455266 0.15 ENST00000266646.3
inhibin subunit beta E
chr7_-_41703062 0.15 ENST00000242208.5
inhibin subunit beta A
chr15_+_88639009 0.14 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr3_-_100114488 0.14 ENST00000477258.2
ENST00000354552.7
ENST00000331335.9
ENST00000398326.2
filamin A interacting protein 1 like
chr19_-_4338786 0.14 ENST00000601482.1
ENST00000600324.5
ENST00000594605.6
signal transducing adaptor family member 2
chr3_+_119173515 0.14 ENST00000497685.5
uroplakin 1B
chr4_-_185956652 0.14 ENST00000355634.9
sorbin and SH3 domain containing 2
chr11_-_695215 0.14 ENST00000382409.4
DEAF1 transcription factor
chr1_+_155078829 0.13 ENST00000368408.4
ephrin A3
chr8_-_65789084 0.13 ENST00000379419.8
phosphodiesterase 7A
chr17_-_3691887 0.13 ENST00000552050.5
purinergic receptor P2X 5
chr1_+_172452885 0.13 ENST00000367725.4
chromosome 1 open reading frame 105
chr15_+_21651844 0.13 ENST00000623441.1
olfactory receptor family 4 subfamily N member 4C
chr17_-_41009124 0.13 ENST00000391588.3
keratin associated protein 3-1
chr17_-_41124178 0.13 ENST00000394014.2
keratin associated protein 4-12
chr6_-_65707214 0.13 ENST00000370621.7
ENST00000393380.6
ENST00000503581.6
eyes shut homolog
chr8_+_106447918 0.13 ENST00000442977.6
oxidation resistance 1
chr1_-_153550083 0.13 ENST00000368714.1
S100 calcium binding protein A4
chr10_-_119536533 0.12 ENST00000392865.5
regulator of G protein signaling 10
chr11_-_119381629 0.12 ENST00000260187.7
ENST00000455332.6
ubiquitin specific peptidase 2
chr7_+_151086466 0.12 ENST00000397238.7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr8_-_92017637 0.12 ENST00000422361.6
RUNX1 partner transcriptional co-repressor 1
chr12_-_56934403 0.12 ENST00000293502.2
short chain dehydrogenase/reductase family 9C member 7
chr4_-_24912886 0.12 ENST00000504487.5
coiled-coil domain containing 149
chr8_-_41665200 0.12 ENST00000335651.6
ankyrin 1
chr10_-_62816341 0.12 ENST00000242480.4
ENST00000637191.1
early growth response 2
chr19_+_44777860 0.12 ENST00000341505.4
ENST00000647358.2
Cbl proto-oncogene C
chr9_+_12775012 0.12 ENST00000319264.4
leucine rich adaptor protein 1 like
chr1_-_150876571 0.12 ENST00000354396.6
ENST00000358595.10
ENST00000505755.5
aryl hydrocarbon receptor nuclear translocator
chr6_+_101393699 0.12 ENST00000369134.9
ENST00000684068.1
ENST00000683903.1
ENST00000681975.1
glutamate ionotropic receptor kainate type subunit 2
chr8_-_80080816 0.12 ENST00000520527.5
ENST00000517427.5
ENST00000379097.7
ENST00000448733.3
tumor protein D52
chr7_-_76626127 0.12 ENST00000454397.1
POM121 and ZP3 fusion
chr4_-_24912954 0.12 ENST00000502801.1
ENST00000635206.2
coiled-coil domain containing 149
chr19_-_4454084 0.11 ENST00000591919.5
UBX domain protein 6
chr1_-_150876697 0.11 ENST00000515192.5
aryl hydrocarbon receptor nuclear translocator
chr11_-_89063631 0.11 ENST00000455756.6
glutamate metabotropic receptor 5
chr7_-_29989774 0.11 ENST00000242059.10
secernin 1
chr19_-_6720641 0.11 ENST00000245907.11
complement C3
chr7_-_29990113 0.11 ENST00000426154.5
ENST00000421434.5
ENST00000434476.6
secernin 1
chr17_-_19748285 0.11 ENST00000570414.1
ENST00000225740.11
aldehyde dehydrogenase 3 family member A1
chr18_+_13277351 0.11 ENST00000679091.1
low density lipoprotein receptor class A domain containing 4
chr17_-_19748341 0.11 ENST00000395555.7
aldehyde dehydrogenase 3 family member A1
chr2_+_74002685 0.11 ENST00000305799.8
tet methylcytosine dioxygenase 3
chr17_-_49209217 0.11 ENST00000515635.5
G protein subunit gamma transducin 2
chr15_+_40239857 0.11 ENST00000260404.8
p21 (RAC1) activated kinase 6
chr10_-_62816309 0.11 ENST00000411732.3
early growth response 2
chr17_-_19748355 0.10 ENST00000494157.6
aldehyde dehydrogenase 3 family member A1
chr1_+_81306096 0.10 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
adhesion G protein-coupled receptor L2
chr19_+_35106510 0.10 ENST00000648240.1
novel protein
chr11_-_1486763 0.10 ENST00000329957.7
MOB kinase activator 2
chr12_-_52473798 0.10 ENST00000252250.7
keratin 6C
chr14_-_75981986 0.10 ENST00000238682.8
transforming growth factor beta 3
chr12_-_7092422 0.10 ENST00000543835.5
ENST00000647956.2
ENST00000535233.6
complement C1r
chr11_+_64237420 0.10 ENST00000541681.1
vascular endothelial growth factor B
chr7_+_74964692 0.10 ENST00000616305.2
cytosolic arginine sensor for mTORC1 subunit 2
chr16_+_29663219 0.10 ENST00000436527.5
ENST00000360121.4
ENST00000652691.1
ENST00000449759.2
sialophorin
quinolinate phosphoribosyltransferase
chr22_+_23894375 0.10 ENST00000215754.8
macrophage migration inhibitory factor
chr12_+_26195647 0.10 ENST00000535504.1
sarcospan
chr7_-_122699108 0.10 ENST00000340112.3
ring finger protein 133
chr21_-_32813679 0.10 ENST00000487113.1
ENST00000382373.4
chromosome 21 open reading frame 62
chr19_-_18919348 0.09 ENST00000349893.8
ENST00000351079.8
ENST00000600932.5
ENST00000262812.9
COPI coat complex subunit epsilon
chr19_+_35758143 0.09 ENST00000444637.6
ENST00000396908.8
ENST00000301165.9
proline and serine rich 3
chr12_+_116559381 0.09 ENST00000556529.4
microtubule associated protein 1 light chain 3 beta 2
chr10_+_100999287 0.09 ENST00000370220.1
leucine zipper tumor suppressor 2
chr22_+_44702186 0.09 ENST00000336985.11
ENST00000403696.5
ENST00000457960.5
ENST00000361473.9
proline rich 5
PRR5-ARHGAP8 readthrough
chr17_-_41118369 0.09 ENST00000391413.4
keratin associated protein 4-11
chr8_-_109644766 0.09 ENST00000533065.5
ENST00000276646.14
syntabulin
chr22_+_20917398 0.09 ENST00000354336.8
CRK like proto-oncogene, adaptor protein
chr15_-_65115185 0.09 ENST00000559089.6
ubiquitin associated protein 1 like
chr7_+_30134956 0.09 ENST00000324453.13
ENST00000409688.1
maturin, neural progenitor differentiation regulator homolog
chr10_-_96271508 0.09 ENST00000427367.6
ENST00000413476.6
ENST00000371176.6
B cell linker
chr1_-_154870264 0.09 ENST00000618040.4
ENST00000271915.9
potassium calcium-activated channel subfamily N member 3
chr10_+_119029711 0.09 ENST00000425699.3
nanos C2HC-type zinc finger 1
chrX_+_68693629 0.09 ENST00000374597.3
StAR related lipid transfer domain containing 8
chr19_+_1241733 0.09 ENST00000395633.5
ENST00000215375.7
ENST00000591660.5
ATP synthase F1 subunit delta
chr20_-_32536383 0.09 ENST00000375678.7
nucleolar protein 4 like
chr10_-_59709842 0.09 ENST00000395348.8
solute carrier family 16 member 9
chr1_-_225924228 0.09 ENST00000343818.11
ENST00000612039.4
ENST00000432920.2
pyrroline-5-carboxylate reductase 2
novel protein
chr17_-_4987354 0.08 ENST00000361571.9
calmodulin binding transcription activator 2
chr18_+_46333956 0.08 ENST00000587853.1
ring finger protein 165
chr11_+_117203135 0.08 ENST00000529622.1
transgelin
chr1_-_74198132 0.08 ENST00000370911.7
ENST00000370909.6
ENST00000354431.9
leucine rich repeats and IQ motif containing 3
chr2_+_232697362 0.08 ENST00000482666.5
ENST00000483164.5
ENST00000490229.5
ENST00000464805.5
ENST00000489328.1
GRB10 interacting GYF protein 2
chr16_-_84239750 0.08 ENST00000568181.1
potassium voltage-gated channel modifier subfamily G member 4
chr10_+_94402486 0.08 ENST00000225235.5
TBC1 domain family member 12
chr11_-_796185 0.08 ENST00000533385.5
ENST00000528936.5
ENST00000629634.2
ENST00000625752.2
ENST00000528606.5
ENST00000320230.9
solute carrier family 25 member 22
chr17_+_51165815 0.08 ENST00000513177.5
NME/NM23 nucleoside diphosphate kinase 2
chr17_-_43661915 0.08 ENST00000318579.9
ENST00000393661.2
mesenchyme homeobox 1
chr1_-_153390976 0.08 ENST00000368732.5
ENST00000368733.4
S100 calcium binding protein A8
chr3_+_189631373 0.08 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chrX_-_49233309 0.08 ENST00000376251.5
ENST00000323022.10
ENST00000376265.2
calcium voltage-gated channel subunit alpha1 F
chr10_+_122112957 0.08 ENST00000369001.5
transforming acidic coiled-coil containing protein 2
chr16_+_21684429 0.08 ENST00000388956.8
otoancorin
chr19_+_46303599 0.08 ENST00000300862.7
hypoxia inducible factor 3 subunit alpha
chr17_-_49209367 0.08 ENST00000300406.6
ENST00000511277.5
ENST00000511673.1
G protein subunit gamma transducin 2
chr2_+_136765508 0.08 ENST00000409968.6
thrombospondin type 1 domain containing 7B
chr12_+_40692413 0.08 ENST00000551295.7
ENST00000547702.5
ENST00000551424.5
contactin 1
chr6_+_26124161 0.08 ENST00000377791.4
ENST00000602637.1
H2A clustered histone 6
chr4_-_185956348 0.08 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
sorbin and SH3 domain containing 2
chr6_+_135181361 0.08 ENST00000527615.5
ENST00000420123.6
ENST00000525369.5
ENST00000528774.5
ENST00000533624.5
ENST00000534044.5
ENST00000534121.5
MYB proto-oncogene, transcription factor
chr19_-_49020523 0.08 ENST00000637680.1
novel protein
chr1_+_27935110 0.08 ENST00000549094.1
sphingomyelin phosphodiesterase acid like 3B
chr19_+_15049469 0.08 ENST00000427043.4
caspase 14
chr11_-_125592448 0.08 ENST00000648911.1
fasciculation and elongation protein zeta 1
chr1_-_206772484 0.08 ENST00000423557.1
interleukin 10
chr16_-_79599902 0.07 ENST00000569649.1
MAF bZIP transcription factor
chr18_+_58045683 0.07 ENST00000592846.5
ENST00000675801.1
NEDD4 like E3 ubiquitin protein ligase
chr1_-_162023632 0.07 ENST00000367940.2
olfactomedin like 2B
chr11_-_2149603 0.07 ENST00000643349.1
novel protein
chr2_+_68774782 0.07 ENST00000409030.7
ENST00000409220.5
Rho GTPase activating protein 25
chr10_-_96271553 0.07 ENST00000224337.10
B cell linker
chr1_+_1632152 0.07 ENST00000472264.1
ENST00000356026.10
ENST00000378675.7
matrix metallopeptidase 23B
chr7_+_5190273 0.07 ENST00000382384.6
WD repeat domain, phosphoinositide interacting 2
chr6_-_30075767 0.07 ENST00000244360.8
ENST00000376751.8
ring finger protein 39
chr12_-_57752265 0.07 ENST00000547281.5
ENST00000257904.11
ENST00000546489.5
ENST00000552388.1
cyclin dependent kinase 4
chr1_-_225923891 0.07 ENST00000472798.2
ENST00000489681.5
ENST00000612651.4
pyrroline-5-carboxylate reductase 2
chr1_+_6448022 0.07 ENST00000416731.5
ENST00000461727.6
espin
chr12_-_123268077 0.07 ENST00000542174.5
cyclin dependent kinase 2 associated protein 1
chr5_-_36241798 0.07 ENST00000514504.5
NAD kinase 2, mitochondrial
chr12_-_57752345 0.07 ENST00000551800.5
ENST00000549606.5
ENST00000312990.10
cyclin dependent kinase 4
chr16_-_88977196 0.07 ENST00000268679.9
CBFA2/RUNX1 partner transcriptional co-repressor 3
chr7_-_31340678 0.07 ENST00000297142.4
neuronal differentiation 6
chr1_+_27934980 0.07 ENST00000373894.8
sphingomyelin phosphodiesterase acid like 3B
chr10_+_21524627 0.07 ENST00000651097.1
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr9_+_132162045 0.07 ENST00000393229.4
netrin G2
chr17_+_40177460 0.07 ENST00000620260.6
Rap guanine nucleotide exchange factor like 1
chr12_+_112978424 0.07 ENST00000680685.1
ENST00000620097.2
2'-5'-oligoadenylate synthetase 2
chr10_+_49610297 0.07 ENST00000374115.5
solute carrier family 18 member A3
chr15_-_63156774 0.07 ENST00000462430.5
ribosomal protein S27 like
chr12_+_112978460 0.07 ENST00000449768.2
2'-5'-oligoadenylate synthetase 2
chr11_-_95232514 0.07 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
sestrin 3
chr4_-_185812209 0.07 ENST00000393523.6
ENST00000393528.7
ENST00000449407.6
sorbin and SH3 domain containing 2
chr18_+_3448456 0.07 ENST00000549780.5
TGFB induced factor homeobox 1
chrX_+_118974608 0.07 ENST00000304778.11
ENST00000371628.8
LON peptidase N-terminal domain and ring finger 3
chr2_+_190649062 0.07 ENST00000409581.5
ENST00000337386.10
NGFI-A binding protein 1
chr1_-_115841116 0.07 ENST00000320238.3
nescient helix-loop-helix 2
chr7_-_11832190 0.07 ENST00000423059.9
ENST00000617773.1
thrombospondin type 1 domain containing 7A
chr15_+_66453418 0.07 ENST00000566326.1
mitogen-activated protein kinase kinase 1
chr16_+_23835946 0.07 ENST00000321728.12
ENST00000643927.1
protein kinase C beta
chr2_+_127423265 0.07 ENST00000402125.2
protein C, inactivator of coagulation factors Va and VIIIa
chr17_+_69502397 0.06 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chr18_+_58045642 0.06 ENST00000676223.1
ENST00000675147.1
NEDD4 like E3 ubiquitin protein ligase
chr11_-_64245816 0.06 ENST00000542235.1
protein phosphatase 1 regulatory inhibitor subunit 14B
chr8_-_22156789 0.06 ENST00000306317.7
leucine rich repeat LGI family member 3
chr8_-_140764386 0.06 ENST00000520151.5
ENST00000519024.5
ENST00000519465.5
protein tyrosine kinase 2
chr2_+_127419882 0.06 ENST00000409048.1
protein C, inactivator of coagulation factors Va and VIIIa
chr6_+_42746958 0.06 ENST00000614467.4
BRD4 interacting chromatin remodeling complex associated protein like
chr7_+_129368123 0.06 ENST00000460109.5
ENST00000474594.5
adenosylhomocysteinase like 2
chr2_+_184598520 0.06 ENST00000302277.7
zinc finger protein 804A
chr3_+_100114911 0.06 ENST00000489081.5
cms1 ribosomal small subunit homolog

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG2_NEUROD1_ATOH1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.4 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.4 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.3 GO:0002086 diaphragm contraction(GO:0002086)
0.1 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.2 GO:0021593 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.0 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.9 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.2 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0002445 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.0 0.1 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.9 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808) negative regulation of hypersensitivity(GO:0002884)
0.0 0.1 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.2 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.1 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.1 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0043449 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.4 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.0 0.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.0 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0015870 acetylcholine transport(GO:0015870)
0.0 0.0 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.0 0.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.9 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.0 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.0 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.3 GO:0021756 striatum development(GO:0021756)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 2.9 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.0 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 3.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0016497 substance K receptor activity(GO:0016497)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0004914 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling