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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for OLIG3_NEUROD2_NEUROG2

Z-value: 1.94

Motif logo

Transcription factors associated with OLIG3_NEUROD2_NEUROG2

Gene Symbol Gene ID Gene Info
ENSG00000177468.7 oligodendrocyte transcription factor 3
ENSG00000171532.5 neuronal differentiation 2
ENSG00000178403.4 neurogenin 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NEUROD2hg38_v1_chr17_-_39607876_39607966-0.686.3e-02Click!
NEUROG2hg38_v1_chr4_-_112516176_1125161810.639.7e-02Click!
OLIG3hg38_v1_chr6_-_137494387_137494400-0.314.5e-01Click!

Activity profile of OLIG3_NEUROD2_NEUROG2 motif

Sorted Z-values of OLIG3_NEUROD2_NEUROG2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91179355 3.68 ENST00000550563.5
ENST00000546370.5
decorin
chr5_-_111976925 3.58 ENST00000395634.7
neuronal regeneration related protein
chr12_-_91179472 3.37 ENST00000550099.5
ENST00000546391.5
decorin
chr12_-_91153149 2.33 ENST00000550758.1
decorin
chr2_-_187513641 2.24 ENST00000392365.5
ENST00000435414.5
tissue factor pathway inhibitor
chr3_-_195583931 1.94 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
apolipoprotein D
chr2_+_188974364 1.89 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr8_-_92017637 1.53 ENST00000422361.6
RUNX1 partner transcriptional co-repressor 1
chr5_-_76623391 1.44 ENST00000296641.5
ENST00000504899.1
coagulation factor II thrombin receptor like 2
chr9_+_18474100 1.14 ENST00000327883.11
ENST00000431052.6
ENST00000380570.8
ENST00000380548.9
ADAMTS like 1
chr15_-_63156774 1.04 ENST00000462430.5
ribosomal protein S27 like
chr4_+_113292838 0.95 ENST00000672411.1
ENST00000673231.1
ankyrin 2
chr6_-_56851888 0.94 ENST00000312431.10
ENST00000520645.5
dystonin
chr4_+_113292925 0.93 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ankyrin 2
chr6_+_72366730 0.93 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr9_-_92482499 0.91 ENST00000375544.7
asporin
chr12_-_108320635 0.89 ENST00000412676.5
ENST00000550573.5
chemerin chemokine-like receptor 1
chr1_-_186375671 0.88 ENST00000451586.1
translocated promoter region, nuclear basket protein
chr3_-_114758940 0.85 ENST00000464560.5
zinc finger and BTB domain containing 20
chr3_-_114759115 0.82 ENST00000471418.5
zinc finger and BTB domain containing 20
chr16_+_21704963 0.81 ENST00000388957.3
otoancorin
chr16_+_53099100 0.80 ENST00000565832.5
chromodomain helicase DNA binding protein 9
chr20_+_36214373 0.79 ENST00000432603.1
erythrocyte membrane protein band 4.1 like 1
chr2_+_157257687 0.78 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr2_+_209580024 0.77 ENST00000392194.5
microtubule associated protein 2
chr6_-_46491431 0.72 ENST00000371374.6
regulator of calcineurin 2
chr4_+_54229261 0.71 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chr1_+_103750406 0.71 ENST00000370079.3
amylase alpha 1C
chr3_-_18438767 0.69 ENST00000454909.6
SATB homeobox 1
chr2_+_209579598 0.68 ENST00000445941.5
ENST00000673860.1
microtubule associated protein 2
chr6_-_31680377 0.68 ENST00000383237.4
lymphocyte antigen 6 family member G5C
chr4_-_158173004 0.66 ENST00000585682.6
golgi associated kinase 1B
chr7_-_98252117 0.66 ENST00000420697.1
ENST00000415086.5
ENST00000447648.7
tectonin beta-propeller repeat containing 1
chr6_-_46491956 0.66 ENST00000306764.11
regulator of calcineurin 2
chr22_-_28306645 0.66 ENST00000612946.4
tetratricopeptide repeat domain 28
chr7_+_134745460 0.65 ENST00000436461.6
caldesmon 1
chr12_+_25973748 0.62 ENST00000542865.5
Ras association domain family member 8
chr4_+_159267737 0.62 ENST00000264431.8
Rap guanine nucleotide exchange factor 2
chr2_+_33134579 0.62 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr16_-_66549839 0.62 ENST00000527800.6
ENST00000677555.1
ENST00000563369.6
thymidine kinase 2
chr10_-_77090722 0.61 ENST00000638531.1
potassium calcium-activated channel subfamily M alpha 1
chr3_-_9952337 0.61 ENST00000411976.2
ENST00000412055.6
proline rich transmembrane protein 3
chr2_+_33134620 0.60 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr5_-_59430600 0.60 ENST00000636120.1
phosphodiesterase 4D
chr14_-_74612226 0.59 ENST00000261978.9
latent transforming growth factor beta binding protein 2
chr22_+_35381086 0.58 ENST00000216117.9
ENST00000677931.1
ENST00000679074.1
heme oxygenase 1
chr2_-_162243375 0.57 ENST00000188790.9
ENST00000443424.5
fibroblast activation protein alpha
chr1_+_89524819 0.54 ENST00000439853.6
ENST00000330947.7
ENST00000449440.5
ENST00000640258.1
leucine rich repeat containing 8 VRAC subunit B
chr1_+_89524871 0.53 ENST00000639264.1
leucine rich repeat containing 8 VRAC subunit B
chr2_-_174598206 0.53 ENST00000392546.6
ENST00000436221.1
WAS/WASL interacting protein family member 1
chr6_-_52994248 0.52 ENST00000457564.1
ENST00000370960.5
glutathione S-transferase alpha 4
chr3_-_179266971 0.50 ENST00000349697.2
ENST00000497599.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr2_+_108377947 0.49 ENST00000272452.7
sulfotransferase family 1C member 4
chr20_-_41317602 0.49 ENST00000559234.5
ENST00000683867.1
zinc fingers and homeoboxes 3
chr4_-_158173042 0.47 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr7_+_29563820 0.47 ENST00000319694.3
proline rich 15
chr12_-_91179517 0.45 ENST00000551354.1
decorin
chr6_+_2999885 0.45 ENST00000397717.7
ENST00000380455.11
N-ribosyldihydronicotinamide:quinone reductase 2
chr6_+_2999961 0.44 ENST00000338130.7
N-ribosyldihydronicotinamide:quinone reductase 2
chr6_+_2999984 0.44 ENST00000380441.5
ENST00000380454.8
N-ribosyldihydronicotinamide:quinone reductase 2
chr1_-_53738024 0.43 ENST00000628545.1
GLIS family zinc finger 1
chr12_+_54854505 0.43 ENST00000308796.11
ENST00000619042.1
mucin like 1
chr18_-_58629084 0.42 ENST00000361673.4
alpha kinase 2
chr15_+_62561361 0.42 ENST00000561311.5
talin 2
chrX_+_71578435 0.41 ENST00000373696.8
germ cell nuclear acidic peptidase
chr8_-_134510182 0.41 ENST00000521673.5
zinc finger and AT-hook domain containing
chr15_-_55408018 0.40 ENST00000569205.5
cell cycle progression 1
chr17_+_14301069 0.39 ENST00000360954.3
heparan sulfate-glucosamine 3-sulfotransferase 3B1
chr17_-_55732074 0.39 ENST00000575734.5
transmembrane protein 100
chr3_+_148739798 0.39 ENST00000402260.2
angiotensin II receptor type 1
chr10_+_134465 0.39 ENST00000439456.5
ENST00000397962.8
ENST00000309776.8
ENST00000397959.7
zinc finger MYND-type containing 11
chr9_+_2110354 0.39 ENST00000634772.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_135741717 0.39 ENST00000415164.5
UBX domain protein 4
chr22_+_43923755 0.38 ENST00000423180.2
ENST00000216180.8
patatin like phospholipase domain containing 3
chr6_-_2744126 0.38 ENST00000647417.1
myosin light chain kinase family member 4
chr2_-_181680490 0.36 ENST00000684145.1
ENST00000295108.4
ENST00000684079.1
ENST00000683430.1
ceramide kinase like
neuronal differentiation 1
chr2_+_108378176 0.36 ENST00000409309.3
sulfotransferase family 1C member 4
chr1_-_19484635 0.34 ENST00000433834.5
capping actin protein of muscle Z-line subunit beta
chr5_-_172006567 0.34 ENST00000517395.6
ENST00000265094.9
ENST00000393802.6
F-box and WD repeat domain containing 11
chr10_-_28282086 0.34 ENST00000375719.7
ENST00000375732.5
membrane palmitoylated protein 7
chr17_+_68515399 0.34 ENST00000588188.6
protein kinase cAMP-dependent type I regulatory subunit alpha
chr3_+_141324208 0.34 ENST00000509842.5
zinc finger and BTB domain containing 38
chr5_+_141359970 0.34 ENST00000522605.2
ENST00000622527.1
protocadherin gamma subfamily B, 2
chr2_+_10368645 0.33 ENST00000613496.4
hippocalcin like 1
chr9_-_127873462 0.33 ENST00000223836.10
adenylate kinase 1
chr7_-_38363476 0.33 ENST00000426402.2
T cell receptor gamma variable 2
chr17_-_50767505 0.32 ENST00000450727.6
ANKRD40 C-terminal like
chr5_-_138338325 0.32 ENST00000510119.1
ENST00000513970.5
cell division cycle 25C
chr10_-_48604952 0.31 ENST00000417912.6
Rho GTPase activating protein 22
chr19_+_14440254 0.31 ENST00000342216.8
protein kinase N1
chr9_+_76459152 0.30 ENST00000444201.6
ENST00000376730.5
glucosaminyl (N-acetyl) transferase 1
chr3_-_149377637 0.30 ENST00000305366.8
transmembrane 4 L six family member 1
chr13_-_113658197 0.30 ENST00000335288.5
ATPase H+/K+ transporting subunit beta
chr16_-_4846196 0.30 ENST00000589389.5
glyoxylate reductase 1 homolog
chr12_+_133080875 0.29 ENST00000412146.6
ENST00000544426.5
ENST00000355557.7
ENST00000319849.7
ENST00000440550.6
zinc finger protein 140
chr8_-_23457677 0.29 ENST00000356206.10
ENST00000417069.6
ectonucleoside triphosphate diphosphohydrolase 4
chr5_+_136160986 0.29 ENST00000507637.1
SMAD family member 5
chr7_+_148590760 0.29 ENST00000307003.3
chromosome 7 open reading frame 33
chr9_-_120477354 0.28 ENST00000416449.5
CDK5 regulatory subunit associated protein 2
chr12_-_10454485 0.27 ENST00000408006.7
ENST00000544822.2
ENST00000536188.5
killer cell lectin like receptor C1
chr5_-_172006817 0.27 ENST00000296933.10
F-box and WD repeat domain containing 11
chr1_+_148889403 0.27 ENST00000464103.5
ENST00000534536.5
ENST00000369356.8
ENST00000369354.7
ENST00000369347.8
ENST00000369349.7
ENST00000369351.7
phosphodiesterase 4D interacting protein
chr13_+_31945826 0.26 ENST00000647500.1
FRY microtubule binding protein
chr11_-_26722051 0.26 ENST00000396005.8
solute carrier family 5 member 12
chr21_+_36135071 0.26 ENST00000290354.6
carbonyl reductase 3
chr14_+_22147988 0.25 ENST00000390457.2
T cell receptor alpha variable 27
chr2_+_71068278 0.25 ENST00000613852.4
ENST00000455662.6
ENST00000531934.5
N-acetylglucosamine kinase
chr9_+_12775012 0.25 ENST00000319264.4
leucine rich adaptor protein 1 like
chr2_-_165203870 0.25 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
sodium voltage-gated channel alpha subunit 3
chr5_+_141968886 0.25 ENST00000347642.7
ring finger protein 14
chr9_+_132162045 0.25 ENST00000393229.4
netrin G2
chr12_-_130839230 0.25 ENST00000392373.7
ENST00000261653.10
syntaxin 2
chr2_+_10368764 0.24 ENST00000620771.4
hippocalcin like 1
chr4_+_70592253 0.24 ENST00000322937.10
ENST00000613447.4
ameloblastin
chr1_-_111427731 0.24 ENST00000369732.4
oviductal glycoprotein 1
chr10_-_48605032 0.24 ENST00000249601.9
Rho GTPase activating protein 22
chr15_+_74173693 0.23 ENST00000249842.8
immunoglobulin superfamily containing leucine rich repeat
chr8_-_23457618 0.23 ENST00000358689.9
ENST00000518718.1
ectonucleoside triphosphate diphosphohydrolase 4
chrX_-_103502853 0.23 ENST00000372633.1
RAB40A, member RAS oncogene family
chr10_-_13707536 0.23 ENST00000632570.1
ENST00000477221.2
FERM domain containing 4A
chr5_+_141373878 0.22 ENST00000517434.3
ENST00000610583.1
protocadherin gamma subfamily A, 6
chr9_-_101594995 0.21 ENST00000636434.1
protein phosphatase 3 regulatory subunit B, beta
chr2_-_177392673 0.21 ENST00000447413.1
ENST00000397057.6
ENST00000456746.5
ENST00000464747.5
novel transcript
nuclear factor, erythroid 2 like 2
chrX_-_70289888 0.21 ENST00000239666.9
ENST00000374454.1
PDZ domain containing 11
chr17_-_8867639 0.21 ENST00000619866.5
phosphoinositide-3-kinase regulatory subunit 6
chrX_+_47585212 0.21 ENST00000445623.1
TIMP metallopeptidase inhibitor 1
chr22_+_42074240 0.21 ENST00000321753.8
PH domain containing endocytic trafficking adaptor 2
chr16_+_28878382 0.21 ENST00000357084.7
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr2_+_74554692 0.20 ENST00000233668.10
ENST00000340004.6
docking protein 1
chr20_-_35529618 0.20 ENST00000246199.5
ENST00000424444.1
ENST00000374345.8
ENST00000444723.3
chromosome 20 open reading frame 173
chr2_-_97094882 0.20 ENST00000414820.6
ENST00000272610.3
fumarylacetoacetate hydrolase domain containing 2B
chr11_+_77066985 0.19 ENST00000456580.6
calpain 5
chr7_+_91264426 0.19 ENST00000287934.4
frizzled class receptor 1
chr17_-_15260752 0.19 ENST00000676329.1
ENST00000675551.1
ENST00000644020.1
ENST00000674947.1
peripheral myelin protein 22
chr1_+_248508073 0.19 ENST00000641804.1
olfactory receptor family 2 subfamily G member 6
chr11_+_77066948 0.19 ENST00000527066.5
ENST00000648180.1
ENST00000529629.5
calpain 5
chr12_+_9971402 0.19 ENST00000304361.9
ENST00000396507.7
ENST00000434319.6
C-type lectin domain family 12 member A
chr2_+_54115437 0.19 ENST00000303536.8
ENST00000394666.7
acylphosphatase 2
chr16_+_28878480 0.19 ENST00000395503.9
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr19_+_11925062 0.19 ENST00000622593.4
ENST00000590798.1
zinc finger protein 700
novel protein
chr17_-_69268812 0.18 ENST00000586811.1
ATP binding cassette subfamily A member 5
chrX_-_13817346 0.18 ENST00000356942.9
glycoprotein M6B
chr11_+_124183219 0.18 ENST00000641351.2
olfactory receptor family 10 subfamily D member 3
chr19_+_11925098 0.18 ENST00000254321.10
ENST00000591944.1
zinc finger protein 700
novel protein
chr11_-_60855943 0.18 ENST00000332539.5
prostaglandin D2 receptor 2
chr11_-_134253248 0.18 ENST00000392595.6
ENST00000352327.5
ENST00000341541.8
ENST00000392594.7
thymocyte nuclear protein 1
chr19_+_44259903 0.18 ENST00000588489.5
ENST00000391958.6
zinc finger protein 233
chr3_-_16513643 0.18 ENST00000334133.9
raftlin, lipid raft linker 1
chr1_-_155241220 0.17 ENST00000368373.8
ENST00000427500.7
glucosylceramidase beta
chr12_-_10849464 0.17 ENST00000544994.5
ENST00000228811.8
ENST00000540107.2
proline rich 4
chr11_-_89063631 0.17 ENST00000455756.6
glutamate metabotropic receptor 5
chr12_+_56468561 0.17 ENST00000338146.7
SPRY domain containing 4
chr6_-_111793871 0.17 ENST00000368667.6
FYN proto-oncogene, Src family tyrosine kinase
chrX_+_118974608 0.17 ENST00000304778.11
ENST00000371628.8
LON peptidase N-terminal domain and ring finger 3
chr21_-_42366525 0.17 ENST00000291527.3
trefoil factor 1
chr19_-_21329400 0.17 ENST00000356929.3
zinc finger protein 708
chr11_+_134253531 0.17 ENST00000374752.6
ENST00000281182.9
acyl-CoA dehydrogenase family member 8
chr6_+_69232406 0.17 ENST00000238918.12
adhesion G protein-coupled receptor B3
chr17_-_60392333 0.17 ENST00000590133.5
ubiquitin specific peptidase 32
chr5_+_141370236 0.17 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr3_-_146460440 0.16 ENST00000610787.5
phospholipid scramblase 2
chr4_+_73853290 0.16 ENST00000226524.4
platelet factor 4 variant 1
chr19_+_55640966 0.16 ENST00000590190.1
ENST00000325333.10
ENST00000585995.1
ENST00000592996.5
zinc finger protein 580
zinc finger protein 581
coiled-coil domain containing 106
chr5_+_141192330 0.16 ENST00000239446.6
protocadherin beta 10
chr21_-_30480364 0.16 ENST00000390689.3
keratin associated protein 19-1
chr19_+_8413270 0.16 ENST00000381035.8
ENST00000595142.5
ENST00000601724.5
ENST00000601283.5
ENST00000215555.7
ENST00000595213.1
membrane associated ring-CH-type finger 2
chr6_+_151239951 0.16 ENST00000402676.7
A-kinase anchoring protein 12
chr9_+_121299793 0.16 ENST00000373818.8
gelsolin
chr15_-_50265666 0.16 ENST00000543581.5
ENST00000267845.8
histidine decarboxylase
chr5_+_149357999 0.16 ENST00000274569.9
prenylcysteine oxidase 1 like
chr4_-_88823165 0.16 ENST00000508369.5
family with sequence similarity 13 member A
chr17_+_19648915 0.15 ENST00000672567.1
ENST00000672709.1
aldehyde dehydrogenase 3 family member A2
chr16_-_30894264 0.15 ENST00000380317.8
BAF chromatin remodeling complex subunit BCL7C
chr2_+_201129318 0.15 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr10_-_48251757 0.15 ENST00000305531.3
FERM and PDZ domain containing 2
chr3_-_126357399 0.15 ENST00000296233.4
Kruppel like factor 15
chr5_+_170861990 0.15 ENST00000523189.6
RAN binding protein 17
chr9_+_107306459 0.15 ENST00000457811.1
RAD23 homolog B, nucleotide excision repair protein
chr17_-_44268119 0.15 ENST00000399246.3
ENST00000262418.12
solute carrier family 4 member 1 (Diego blood group)
chr3_-_53882142 0.15 ENST00000335754.8
actin related protein 8
chr9_-_124941054 0.15 ENST00000373555.9
golgin A1
chr14_-_23435652 0.14 ENST00000355349.4
myosin heavy chain 7
chr6_+_41042557 0.14 ENST00000373158.6
ENST00000470917.1
translocator protein 2
chrX_+_152914426 0.14 ENST00000318504.11
ENST00000449285.6
ENST00000539731.5
ENST00000535861.5
ENST00000370268.8
ENST00000370270.6
zinc finger protein 185 with LIM domain
chr3_-_146528750 0.14 ENST00000483300.5
phospholipid scramblase 1
chr1_+_100345018 0.14 ENST00000635056.2
ENST00000647005.1
cell division cycle 14A
chr2_+_177392734 0.14 ENST00000680770.1
ENST00000637633.2
ENST00000679459.1
ENST00000409888.1
ENST00000264167.11
ENST00000642466.2
alkylglycerone phosphate synthase
chr9_+_110048598 0.14 ENST00000434623.6
ENST00000374525.5
PALM2 and AKAP2 fusion
chrX_+_154542194 0.14 ENST00000618670.4
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chr4_-_7871986 0.14 ENST00000360265.9
actin filament associated protein 1
chr3_-_49429252 0.14 ENST00000615713.4
nicolin 1
chr16_+_53054973 0.14 ENST00000447540.6
ENST00000615216.4
ENST00000566029.5
chromodomain helicase DNA binding protein 9
chr9_+_128920966 0.14 ENST00000428610.5
ENST00000372592.8
phytanoyl-CoA dioxygenase domain containing 1
chr12_+_133130618 0.13 ENST00000426665.6
ENST00000248211.11
zinc finger protein 10
chrX_+_70290077 0.13 ENST00000374403.4
kinesin family member 4A
chr4_-_88823214 0.13 ENST00000513837.5
ENST00000503556.5
family with sequence similarity 13 member A
chr2_-_105396943 0.13 ENST00000409807.5
four and a half LIM domains 2
chr5_-_131797030 0.13 ENST00000615660.4
folliculin interacting protein 1
chr5_-_134174765 0.13 ENST00000520417.1
S-phase kinase associated protein 1
chr7_+_100049765 0.13 ENST00000456748.6
ENST00000292450.9
ENST00000438937.1
ENST00000543588.2
zinc finger and SCAN domain containing 21

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG3_NEUROD2_NEUROG2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.6 9.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3 0.9 GO:0031453 regulation of heterochromatin assembly(GO:0031445) positive regulation of heterochromatin assembly(GO:0031453)
0.3 1.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 2.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 0.7 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.2 0.6 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.2 0.6 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.2 1.9 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 0.5 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.2 0.6 GO:0097325 melanocyte proliferation(GO:0097325)
0.2 1.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 0.9 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.6 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.5 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.6 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 1.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.2 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 0.2 GO:1904457 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1 1.5 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.9 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.2 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.2 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.2 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.3 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0 0.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.5 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.3 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 1.2 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.2 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 1.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.1 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.0 0.9 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.0 0.9 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.8 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.3 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.1 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.4 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.2 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.4 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.4 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 1.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 1.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 1.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.0 0.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.3 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.1 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.0 0.3 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.2 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.4 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.6 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.0 GO:0050992 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.0 0.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.7 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.7 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.1 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 1.5 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.0 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.6 GO:0097435 fibril organization(GO:0097435)
0.0 0.0 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.2 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.0 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.1 GO:0071033 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0 0.1 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.0 GO:1903182 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.0 0.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 9.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.5 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.2 0.9 GO:0031673 H zone(GO:0031673)
0.1 1.9 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:0030312 external encapsulating structure(GO:0030312)
0.1 0.2 GO:0097180 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 1.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.1 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 2.1 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.1 GO:0097229 sperm end piece(GO:0097229)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 2.9 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 3.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.0 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.0 1.2 GO:0005901 caveola(GO:0005901)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.2 0.7 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 1.2 GO:0050436 microfibril binding(GO:0050436)
0.2 1.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 1.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 1.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 9.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.3 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.3 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 0.6 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.5 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 0.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.3 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 1.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.3 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 0.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.2 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.2 GO:0046577 long-chain-alcohol oxidase activity(GO:0046577)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.0 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.0 GO:0043495 protein anchor(GO:0043495)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.3 GO:0050733 RS domain binding(GO:0050733)
0.0 0.6 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 2.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.4 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.6 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.0 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.0 0.1 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.0 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.0 GO:0009032 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 2.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 1.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 2.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 2.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.9 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis