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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for PAX6

Z-value: 0.71

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Transcription factors associated with PAX6

Gene Symbol Gene ID Gene Info
PAX6
ENSG00000007372.24 paired box 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX6hg38_v1_chr11_-_31811314_31811336-0.531.7e-01Click!

Activity profile of PAX6 motif

Sorted Z-values of PAX6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_63752935 0.73 ENST00000425392.5
ENST00000336429.6
SERPINB7
serpin family B member 7
chr2_-_160200310 0.69 ENST00000620391.4
ITGB6
integrin subunit beta 6
chr1_-_242449478 0.64 ENST00000427495.5
PLD5
phospholipase D family member 5
chr2_-_160200251 0.64 ENST00000428609.6
ENST00000409967.6
ENST00000283249.7
ITGB6
integrin subunit beta 6
chr18_+_63777773 0.64 ENST00000447428.5
ENST00000546027.5
SERPINB7
serpin family B member 7
chr2_-_160200289 0.62 ENST00000409872.1
ITGB6
integrin subunit beta 6
chr11_-_88175432 0.53 ENST00000531138.1
ENST00000526372.1
ENST00000243662.11
RAB38
RAB38, member RAS oncogene family
chr1_+_2073986 0.51 ENST00000461106.6
PRKCZ
protein kinase C zeta
chr1_-_201399302 0.49 ENST00000633953.1
ENST00000391967.7
LAD1
ladinin 1
chr4_+_76435216 0.48 ENST00000296043.7
SHROOM3
shroom family member 3
chr4_+_40192949 0.47 ENST00000507851.5
ENST00000615577.4
ENST00000613272.4
RHOH
ras homolog family member H
chrX_-_107206426 0.47 ENST00000372466.8
ENST00000421752.1
NUP62CL
nucleoporin 62 C-terminal like
chr1_-_159945596 0.45 ENST00000361509.7
ENST00000611023.1
ENST00000368094.6
IGSF9
immunoglobulin superfamily member 9
chr1_-_201399525 0.44 ENST00000367313.4
LAD1
ladinin 1
chr12_+_82686889 0.41 ENST00000321196.8
TMTC2
transmembrane O-mannosyltransferase targeting cadherins 2
chr3_-_125120813 0.40 ENST00000430155.6
SLC12A8
solute carrier family 12 member 8
chr9_+_90827452 0.40 ENST00000375746.1
SYK
spleen associated tyrosine kinase
chr11_-_58575846 0.40 ENST00000395074.7
LPXN
leupaxin
chr5_+_140875299 0.38 ENST00000613593.1
ENST00000398631.3
PCDHA12
protocadherin alpha 12
chr12_-_84912816 0.32 ENST00000680469.1
ENST00000450363.4
ENST00000681106.1
SLC6A15
solute carrier family 6 member 15
chr17_-_41060109 0.32 ENST00000391418.3
KRTAP2-3
keratin associated protein 2-3
chr16_+_71626175 0.31 ENST00000268485.8
ENST00000565261.1
ENST00000299952.4
MARVELD3
MARVEL domain containing 3
chr14_+_61529005 0.28 ENST00000556347.1
ENSG00000258989.1
novel protein
chr12_+_77830886 0.25 ENST00000397909.7
ENST00000549464.5
NAV3
neuron navigator 3
chr1_+_161707244 0.24 ENST00000349527.8
ENST00000294796.8
ENST00000309691.10
ENST00000367953.7
ENST00000367950.2
FCRLA
Fc receptor like A
chr5_+_136058849 0.24 ENST00000508076.5
TGFBI
transforming growth factor beta induced
chr11_+_60924452 0.23 ENST00000453848.7
ENST00000544065.5
ENST00000005286.8
TMEM132A
transmembrane protein 132A
chr17_-_40867200 0.21 ENST00000647902.1
ENST00000251643.5
KRT12
keratin 12
chr10_-_117005570 0.21 ENST00000260777.14
ENST00000392903.3
SHTN1
shootin 1
chr10_+_5196831 0.21 ENST00000263126.3
AKR1C4
aldo-keto reductase family 1 member C4
chr19_+_49388243 0.21 ENST00000447857.8
KASH5
KASH domain containing 5
chrX_+_107206632 0.20 ENST00000535523.5
ENST00000673764.1
DNAAF6
dynein axonemal assembly factor 6
chrX_+_107206605 0.20 ENST00000372453.8
DNAAF6
dynein axonemal assembly factor 6
chr2_+_148978361 0.20 ENST00000678720.1
ENST00000678856.1
ENST00000677080.1
KIF5C
kinesin family member 5C
chr3_-_119660580 0.19 ENST00000493094.6
ENST00000264231.7
ENST00000468801.1
POPDC2
popeye domain containing 2
chrX_-_139832235 0.19 ENST00000327569.7
ENST00000361648.6
ATP11C
ATPase phospholipid transporting 11C
chrX_-_131289412 0.19 ENST00000652189.1
ENST00000651556.1
IGSF1
immunoglobulin superfamily member 1
chr1_+_159439722 0.18 ENST00000641630.1
ENST00000423932.6
OR10J1
olfactory receptor family 10 subfamily J member 1
chr10_-_117005173 0.18 ENST00000355371.9
SHTN1
shootin 1
chr1_-_86914319 0.18 ENST00000611507.4
ENST00000616787.4
SELENOF
selenoprotein F
chr11_-_16356538 0.17 ENST00000683767.1
SOX6
SRY-box transcription factor 6
chr10_-_117005349 0.17 ENST00000615301.4
SHTN1
shootin 1
chr14_+_22314435 0.16 ENST00000390467.3
TRAV40
T cell receptor alpha variable 40
chr7_-_72828171 0.16 ENST00000612372.4
ENST00000610600.1
ENST00000620995.5
TYW1B
tRNA-yW synthesizing protein 1 homolog B
chr1_+_180928133 0.16 ENST00000367587.1
KIAA1614
KIAA1614
chr19_-_35528221 0.16 ENST00000588674.5
ENST00000452271.7
ENST00000518157.1
SBSN
suprabasin
chr1_+_207752046 0.15 ENST00000367042.6
ENST00000322875.8
ENST00000322918.9
ENST00000354848.5
ENST00000357714.5
ENST00000358170.6
ENST00000367041.5
ENST00000367047.5
ENST00000360212.6
ENST00000480003.5
CD46
CD46 molecule
chr1_+_160739265 0.15 ENST00000368042.7
SLAMF7
SLAM family member 7
chr13_+_113158642 0.15 ENST00000375547.7
ENST00000342783.5
PROZ
protein Z, vitamin K dependent plasma glycoprotein
chr1_-_86914102 0.15 ENST00000331835.10
ENST00000401030.4
ENST00000370554.5
SELENOF
selenoprotein F
chr4_+_76074701 0.15 ENST00000355810.9
ENST00000349321.7
ART3
ADP-ribosyltransferase 3 (inactive)
chr8_+_127735597 0.15 ENST00000651626.1
MYC
MYC proto-oncogene, bHLH transcription factor
chr12_-_69699455 0.14 ENST00000266661.8
BEST3
bestrophin 3
chr6_-_10412367 0.14 ENST00000379608.9
TFAP2A
transcription factor AP-2 alpha
chr20_-_45515612 0.14 ENST00000217428.7
SPINT3
serine peptidase inhibitor, Kunitz type 3
chrX_-_66040072 0.14 ENST00000374737.9
VSIG4
V-set and immunoglobulin domain containing 4
chr7_-_152676130 0.14 ENST00000359321.2
XRCC2
X-ray repair cross complementing 2
chr2_+_191245473 0.13 ENST00000304164.8
MYO1B
myosin IB
chr2_+_29097705 0.13 ENST00000401605.5
ENST00000401617.6
CLIP4
CAP-Gly domain containing linker protein family member 4
chr3_-_197299067 0.13 ENST00000663148.1
DLG1
discs large MAGUK scaffold protein 1
chrX_-_66040107 0.13 ENST00000455586.6
VSIG4
V-set and immunoglobulin domain containing 4
chr11_-_117876719 0.13 ENST00000529335.6
ENST00000260282.8
FXYD6
FXYD domain containing ion transport regulator 6
chr6_-_35512863 0.13 ENST00000428978.1
ENST00000614066.4
ENST00000322263.8
TULP1
TUB like protein 1
chr3_+_108296489 0.13 ENST00000619531.4
HHLA2
HERV-H LTR-associating 2
chr8_-_123025750 0.13 ENST00000523036.1
DERL1
derlin 1
chr11_-_117876892 0.12 ENST00000539526.5
FXYD6
FXYD domain containing ion transport regulator 6
chr18_+_58341038 0.12 ENST00000679791.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr10_-_88851809 0.12 ENST00000371930.5
ANKRD22
ankyrin repeat domain 22
chrX_-_131289266 0.12 ENST00000370910.5
ENST00000370901.4
ENST00000361420.8
ENST00000370903.8
IGSF1
immunoglobulin superfamily member 1
chr8_-_3409528 0.12 ENST00000335551.11
CSMD1
CUB and Sushi multiple domains 1
chr6_-_42194947 0.12 ENST00000230361.4
GUCA1B
guanylate cyclase activator 1B
chr5_-_801145 0.12 ENST00000424784.3
ZDHHC11
zinc finger DHHC-type containing 11
chr6_-_35512882 0.12 ENST00000229771.11
TULP1
TUB like protein 1
chr1_-_95072936 0.12 ENST00000370205.6
ALG14
ALG14 UDP-N-acetylglucosaminyltransferase subunit
chr12_-_69699331 0.12 ENST00000548658.1
ENST00000476098.5
BEST3
bestrophin 3
chr10_+_12068945 0.11 ENST00000263035.9
DHTKD1
dehydrogenase E1 and transketolase domain containing 1
chr3_-_197183806 0.11 ENST00000671246.1
ENST00000660553.1
DLG1
discs large MAGUK scaffold protein 1
chr12_+_68686951 0.11 ENST00000378905.6
ENST00000229179.9
NUP107
nucleoporin 107
chr19_-_55160668 0.11 ENST00000588076.1
DNAAF3
dynein axonemal assembly factor 3
chr1_+_152719522 0.11 ENST00000368775.3
C1orf68
chromosome 1 open reading frame 68
chr21_+_38256698 0.11 ENST00000613499.4
ENST00000612702.4
ENST00000398925.5
ENST00000398928.5
ENST00000328656.8
ENST00000443341.5
KCNJ15
potassium inwardly rectifying channel subfamily J member 15
chr1_-_10964201 0.11 ENST00000418570.6
C1orf127
chromosome 1 open reading frame 127
chr1_-_155991198 0.11 ENST00000673475.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2
chr17_+_59220446 0.11 ENST00000284116.9
ENST00000581140.5
ENST00000581276.5
GDPD1
glycerophosphodiester phosphodiesterase domain containing 1
chr7_-_102356444 0.10 ENST00000563237.3
SPDYE6
speedy/RINGO cell cycle regulator family member E6
chr12_-_9999176 0.10 ENST00000298527.10
ENST00000348658.4
CLEC1B
C-type lectin domain family 1 member B
chr4_-_64409444 0.10 ENST00000381210.8
ENST00000507440.5
TECRL
trans-2,3-enoyl-CoA reductase like
chr11_-_18791563 0.10 ENST00000396168.1
PTPN5
protein tyrosine phosphatase non-receptor type 5
chr19_+_15640880 0.10 ENST00000586182.6
ENST00000221307.13
ENST00000591058.5
CYP4F3
cytochrome P450 family 4 subfamily F member 3
chr12_+_110847000 0.10 ENST00000552694.1
CCDC63
coiled-coil domain containing 63
chr14_+_55661272 0.10 ENST00000555573.5
KTN1
kinectin 1
chr16_+_84768246 0.10 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr17_-_60422404 0.10 ENST00000588898.1
USP32
ubiquitin specific peptidase 32
chr1_+_147902789 0.10 ENST00000369235.2
GJA8
gap junction protein alpha 8
chr14_+_67720842 0.10 ENST00000267502.3
RDH12
retinol dehydrogenase 12
chr12_+_112978562 0.10 ENST00000680122.1
OAS2
2'-5'-oligoadenylate synthetase 2
chr17_+_29941605 0.09 ENST00000394835.7
EFCAB5
EF-hand calcium binding domain 5
chr12_+_110846960 0.09 ENST00000545036.5
ENST00000308208.10
CCDC63
coiled-coil domain containing 63
chr7_+_80638633 0.09 ENST00000447544.7
ENST00000482059.6
CD36
CD36 molecule
chr11_+_128693887 0.09 ENST00000281428.12
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr4_+_113049616 0.09 ENST00000504454.5
ENST00000357077.9
ENST00000394537.7
ENST00000672779.1
ENST00000264366.10
ANK2
ankyrin 2
chr12_+_47079586 0.09 ENST00000432328.2
ENST00000546455.6
PCED1B
PC-esterase domain containing 1B
chr15_-_51751525 0.09 ENST00000454181.6
LYSMD2
LysM domain containing 2
chr1_-_165768848 0.09 ENST00000367881.11
ENST00000464650.5
ENST00000612311.4
ENST00000628579.1
TMCO1
transmembrane and coiled-coil domains 1
chr3_-_36739791 0.09 ENST00000416516.2
DCLK3
doublecortin like kinase 3
chr11_-_18791768 0.09 ENST00000358540.7
PTPN5
protein tyrosine phosphatase non-receptor type 5
chr10_+_100462969 0.09 ENST00000343737.6
WNT8B
Wnt family member 8B
chr3_-_51903341 0.09 ENST00000310914.10
IQCF1
IQ motif containing F1
chr15_+_22838635 0.09 ENST00000398014.7
ENST00000359727.8
ENST00000674173.1
ENST00000337451.8
ENST00000674289.1
ENST00000674477.1
ENST00000398013.7
ENST00000674330.1
ENST00000560039.1
ENST00000539711.2
NIPA2
NIPA magnesium transporter 2
chr4_+_186227501 0.09 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
KLKB1
kallikrein B1
chr16_-_47459130 0.09 ENST00000565940.6
ITFG1
integrin alpha FG-GAP repeat containing 1
chr22_+_25742141 0.09 ENST00000536101.5
ENST00000335473.12
ENST00000407587.6
MYO18B
myosin XVIIIB
chr1_+_86914616 0.09 ENST00000370550.10
ENST00000370551.8
HS2ST1
heparan sulfate 2-O-sulfotransferase 1
chr21_+_7748899 0.08 ENST00000623661.1
SMIM11B
small integral membrane protein 11B
chr16_+_56936654 0.08 ENST00000563911.5
HERPUD1
homocysteine inducible ER protein with ubiquitin like domain 1
chr13_+_95433593 0.08 ENST00000376873.7
CLDN10
claudin 10
chr6_-_134052594 0.08 ENST00000275230.6
SLC2A12
solute carrier family 2 member 12
chr16_-_71230676 0.08 ENST00000321489.9
ENST00000539973.5
ENST00000288168.14
ENST00000545267.1
ENST00000541601.5
ENST00000393567.7
ENST00000538248.5
HYDIN
HYDIN axonemal central pair apparatus protein
chrX_+_100666854 0.08 ENST00000640282.1
SRPX2
sushi repeat containing protein X-linked 2
chr8_-_94475044 0.08 ENST00000297592.5
ENST00000336148.10
RAD54B
RAD54 homolog B
chr7_-_76541459 0.08 ENST00000632547.1
SPDYE16
speedy/RINGO cell cycle regulator family member E16
chr13_+_112968496 0.08 ENST00000397030.5
MCF2L
MCF.2 cell line derived transforming sequence like
chr3_-_197299281 0.08 ENST00000419354.5
ENST00000667104.1
ENST00000658701.1
DLG1
discs large MAGUK scaffold protein 1
chr22_+_21420636 0.08 ENST00000407598.2
HIC2
HIC ZBTB transcriptional repressor 2
chr8_+_22059169 0.08 ENST00000358242.5
DMTN
dematin actin binding protein
chr8_-_21913671 0.08 ENST00000523932.1
ENST00000276420.9
DOK2
docking protein 2
chr3_-_128467248 0.08 ENST00000319153.3
DNAJB8
DnaJ heat shock protein family (Hsp40) member B8
chr3_-_197183849 0.07 ENST00000443183.5
DLG1
discs large MAGUK scaffold protein 1
chr20_+_4721901 0.07 ENST00000305817.3
PRND
prion like protein doppel
chr18_-_48137295 0.07 ENST00000535628.6
ZBTB7C
zinc finger and BTB domain containing 7C
chr12_-_14950606 0.07 ENST00000536592.5
ARHGDIB
Rho GDP dissociation inhibitor beta
chr19_+_35448251 0.07 ENST00000599180.3
FFAR2
free fatty acid receptor 2
chr4_-_67883987 0.07 ENST00000283916.11
TMPRSS11D
transmembrane serine protease 11D
chr3_+_171843337 0.07 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
TMEM212
transmembrane protein 212
chr20_+_59163810 0.07 ENST00000371030.4
ZNF831
zinc finger protein 831
chr10_+_35605337 0.07 ENST00000321660.2
GJD4
gap junction protein delta 4
chr18_+_13611429 0.07 ENST00000587757.5
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr10_+_5692792 0.07 ENST00000645567.1
TASOR2
transcription activation suppressor family member 2
chr17_-_69150062 0.07 ENST00000522787.5
ENST00000521538.5
ABCA10
ATP binding cassette subfamily A member 10
chr5_+_80408031 0.07 ENST00000505560.5
ENST00000509562.2
ZFYVE16
zinc finger FYVE-type containing 16
chr8_-_67746348 0.07 ENST00000297770.10
CPA6
carboxypeptidase A6
chr2_-_28870266 0.07 ENST00000306108.10
TRMT61B
tRNA methyltransferase 61B
chr12_-_44875647 0.07 ENST00000395487.6
NELL2
neural EGFL like 2
chr9_+_131190119 0.07 ENST00000483497.6
NUP214
nucleoporin 214
chr4_+_113049479 0.06 ENST00000671727.1
ENST00000671762.1
ENST00000672366.1
ENST00000672502.1
ENST00000672045.1
ENST00000672251.1
ENST00000672854.1
ANK2
ankyrin 2
chr5_+_80407994 0.06 ENST00000338008.9
ENST00000510158.5
ZFYVE16
zinc finger FYVE-type containing 16
chr8_+_22059198 0.06 ENST00000523266.5
ENST00000519907.5
DMTN
dematin actin binding protein
chr19_-_5867741 0.06 ENST00000252675.6
FUT5
fucosyltransferase 5
chr2_-_677367 0.06 ENST00000281017.8
TMEM18
transmembrane protein 18
chr13_+_25301587 0.06 ENST00000381736.8
ENST00000463407.5
ENST00000381718.7
ENST00000381747.7
NUP58
nucleoporin 58
chr7_+_112480853 0.06 ENST00000439068.6
ENST00000312849.4
LSMEM1
leucine rich single-pass membrane protein 1
chr8_-_58500158 0.06 ENST00000301645.4
CYP7A1
cytochrome P450 family 7 subfamily A member 1
chr21_+_38256984 0.06 ENST00000398938.7
KCNJ15
potassium inwardly rectifying channel subfamily J member 15
chr16_-_3717505 0.06 ENST00000538171.5
ENST00000246957.10
TRAP1
TNF receptor associated protein 1
chr8_+_120445402 0.06 ENST00000305949.6
MTBP
MDM2 binding protein
chrX_+_48383516 0.06 ENST00000620320.4
ENST00000595689.3
SSX4
SSX family member 4
chr5_+_40909490 0.06 ENST00000313164.10
C7
complement C7
chr4_-_145180496 0.06 ENST00000447906.8
OTUD4
OTU deubiquitinase 4
chr3_-_112133218 0.06 ENST00000488580.5
ENST00000308910.9
ENST00000460387.6
ENST00000484193.5
ENST00000487901.1
GCSAM
germinal center associated signaling and motility
chr2_-_54987578 0.06 ENST00000486085.5
RTN4
reticulon 4
chr5_+_96876480 0.05 ENST00000437043.8
ENST00000379904.8
ERAP2
endoplasmic reticulum aminopeptidase 2
chr1_+_62194831 0.05 ENST00000498273.2
L1TD1
LINE1 type transposase domain containing 1
chr14_+_63761836 0.05 ENST00000674003.1
SYNE2
spectrin repeat containing nuclear envelope protein 2
chr2_-_219245389 0.05 ENST00000428427.1
ENST00000432839.1
ENST00000295759.12
ENST00000424620.1
GLB1L
galactosidase beta 1 like
chr21_-_14658812 0.05 ENST00000647101.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr19_-_53824288 0.05 ENST00000324134.11
ENST00000391773.6
ENST00000391775.7
ENST00000345770.9
ENST00000391772.1
NLRP12
NLR family pyrin domain containing 12
chr2_-_162074394 0.05 ENST00000676810.1
DPP4
dipeptidyl peptidase 4
chr15_-_84654270 0.05 ENST00000434634.7
WDR73
WD repeat domain 73
chr1_+_207645114 0.05 ENST00000508064.7
CR1L
complement C3b/C4b receptor 1 like
chr12_-_44876294 0.05 ENST00000429094.7
ENST00000551601.5
ENST00000549027.5
ENST00000452445.6
NELL2
neural EGFL like 2
chr9_+_84668485 0.05 ENST00000359847.4
ENST00000395882.6
ENST00000376208.6
ENST00000376213.6
NTRK2
neurotrophic receptor tyrosine kinase 2
chr10_+_116590956 0.05 ENST00000358834.9
ENST00000528052.5
PNLIPRP1
pancreatic lipase related protein 1
chr10_-_100229550 0.05 ENST00000370397.8
CHUK
component of inhibitor of nuclear factor kappa B kinase complex
chr10_+_116591010 0.05 ENST00000530319.5
ENST00000527980.5
ENST00000471549.5
ENST00000534537.5
PNLIPRP1
pancreatic lipase related protein 1
chr7_+_76480510 0.05 ENST00000446820.6
DTX2
deltex E3 ubiquitin ligase 2
chr5_-_142698004 0.05 ENST00000407758.5
ENST00000441680.6
ENST00000419524.6
ENST00000621536.4
FGF1
fibroblast growth factor 1
chrX_-_54998530 0.05 ENST00000545676.5
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr14_+_63204859 0.05 ENST00000555125.1
RHOJ
ras homolog family member J
chr11_-_117876612 0.04 ENST00000584230.1
ENST00000526014.6
ENST00000584394.5
ENST00000614497.5
ENST00000532984.1
FXYD6
FXYD6-FXYD2
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr17_+_44142015 0.04 ENST00000245382.6
HROB
homologous recombination factor with OB-fold
chr15_+_51681483 0.04 ENST00000542355.6
ENST00000220478.8
ENST00000558709.1
SCG3
secretogranin III
chr1_-_54623518 0.04 ENST00000302250.7
ENST00000371304.2
FAM151A
family with sequence similarity 151 member A
chr4_+_70197924 0.04 ENST00000514097.5
ODAM
odontogenic, ameloblast associated
chr1_-_184037695 0.04 ENST00000361927.9
ENST00000649786.1
COLGALT2
collagen beta(1-O)galactosyltransferase 2
chr15_-_25346012 0.04 ENST00000636667.1
UBE3A
ubiquitin protein ligase E3A
chr2_+_201790461 0.04 ENST00000410091.7
CDK15
cyclin dependent kinase 15
chr17_-_2511875 0.04 ENST00000263092.11
ENST00000576976.2
METTL16
methyltransferase like 16
chr7_+_69824565 0.04 ENST00000643587.1
AUTS2
activator of transcription and developmental regulator AUTS2
chr17_-_35560812 0.04 ENST00000674182.1
SLFN14
schlafen family member 14
chr10_+_95711750 0.04 ENST00000453258.6
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr1_+_167329044 0.04 ENST00000367862.9
POU2F1
POU class 2 homeobox 1
chr10_+_112376193 0.04 ENST00000433418.6
ENST00000356116.6
ENST00000354273.5
ACSL5
acyl-CoA synthetase long chain family member 5
chr9_-_114682061 0.04 ENST00000612244.5
TEX48
testis expressed 48
chr18_+_21242254 0.04 ENST00000269218.10
GREB1L
GREB1 like retinoic acid receptor coactivator
chr10_-_133626792 0.04 ENST00000443774.5
ENST00000425520.2
FRG2B
FSHD region gene 2 family member B
chr11_+_844406 0.04 ENST00000397404.5
TSPAN4
tetraspanin 4
chr1_-_165768835 0.04 ENST00000481278.5
TMCO1
transmembrane and coiled-coil domains 1
chrX_-_124963768 0.04 ENST00000371130.7
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr12_+_6840800 0.04 ENST00000541978.5
ENST00000229264.8
ENST00000435982.6
GNB3
G protein subunit beta 3
chr1_+_163321942 0.04 ENST00000271452.8
NUF2
NUF2 component of NDC80 kinetochore complex

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 0.6 GO:0061163 endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650)
0.2 1.9 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.4 GO:0042223 response to molecule of fungal origin(GO:0002238) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)
0.1 0.5 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.5 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.2 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.5 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.4 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.0 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.2 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:1901569 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.5 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.5 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.2 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 0.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.0 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 2.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.0 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.0 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 2.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors