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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for PBX1

Z-value: 1.06

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Transcription factors associated with PBX1

Gene Symbol Gene ID Gene Info
ENSG00000185630.19 PBX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX1hg38_v1_chr1_+_164559739_1645597610.892.8e-03Click!

Activity profile of PBX1 motif

Sorted Z-values of PBX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91179472 1.22 ENST00000550099.5
ENST00000546391.5
decorin
chr14_-_59630582 0.92 ENST00000395090.5
reticulon 1
chr10_+_122560639 0.80 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
deleted in malignant brain tumors 1
chr16_+_15502266 0.78 ENST00000452191.6
bMERB domain containing 1
chr8_-_107497909 0.76 ENST00000517746.6
angiopoietin 1
chr10_+_122560679 0.76 ENST00000657942.1
deleted in malignant brain tumors 1
chr8_-_107498041 0.75 ENST00000297450.7
angiopoietin 1
chr10_+_122560751 0.74 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
deleted in malignant brain tumors 1
chr17_-_1229706 0.73 ENST00000574139.7
ABR activator of RhoGEF and GTPase
chr2_-_189179754 0.67 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr10_+_68106109 0.64 ENST00000540630.5
ENST00000354393.6
myopalladin
chr10_+_68109433 0.63 ENST00000613327.4
ENST00000358913.10
ENST00000373675.3
myopalladin
chr2_-_201697993 0.50 ENST00000428900.6
membrane palmitoylated protein 4
chr2_-_199458689 0.49 ENST00000443023.5
SATB homeobox 2
chr12_+_21526287 0.48 ENST00000256969.7
spexin hormone
chr15_-_93073111 0.47 ENST00000557420.1
ENST00000542321.6
repulsive guidance molecule BMP co-receptor a
chr2_-_199457931 0.44 ENST00000417098.6
SATB homeobox 2
chr13_-_33185994 0.42 ENST00000255486.8
StAR related lipid transfer domain containing 13
chr2_-_201698040 0.41 ENST00000396886.7
ENST00000409143.5
membrane palmitoylated protein 4
chrX_-_93673558 0.39 ENST00000475430.2
ENST00000373079.4
nucleosome assembly protein 1 like 3
chr7_-_27102669 0.38 ENST00000222718.7
homeobox A2
chr6_-_166627244 0.37 ENST00000265678.9
ribosomal protein S6 kinase A2
chr2_+_20447065 0.35 ENST00000272233.6
ras homolog family member B
chr3_-_15797930 0.32 ENST00000683139.1
ankyrin repeat domain 28
chr17_+_60677822 0.32 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3 microtubule associated cell migration factor
chr22_-_38794111 0.30 ENST00000406622.5
ENST00000216068.9
ENST00000406199.3
Sad1 and UNC84 domain containing 2
dynein axonemal light chain 4
chr7_-_102543849 0.29 ENST00000644544.1
uroplakin 3B like 2
chr2_+_12716893 0.28 ENST00000381465.2
ENST00000155926.9
tribbles pseudokinase 2
chr11_-_1757452 0.27 ENST00000427721.3
novel protein
chr16_-_88663065 0.27 ENST00000301012.8
ENST00000569177.5
mevalonate diphosphate decarboxylase
chrX_-_71254527 0.26 ENST00000373978.1
ENST00000373981.5
zinc finger MYM-type containing 3
chr15_-_37101205 0.26 ENST00000338564.9
ENST00000558313.5
ENST00000340545.9
Meis homeobox 2
chr14_-_74084393 0.25 ENST00000350259.8
ENST00000553458.6
aldehyde dehydrogenase 6 family member A1
chr14_+_24114627 0.25 ENST00000559115.5
ENST00000558215.5
ENST00000557810.5
ENST00000561375.5
ENST00000446197.8
ENST00000559796.5
ENST00000560713.5
ENST00000560901.5
ENST00000559382.5
ENST00000561001.5
DDB1 and CUL4 associated factor 11
chr2_+_61905646 0.24 ENST00000311832.5
copper metabolism domain containing 1
chr2_+_190880809 0.24 ENST00000320717.8
glutaminase
chr7_+_7640696 0.24 ENST00000463725.5
ENST00000682710.1
ENST00000636849.1
ENST00000482067.3
ENST00000469183.5
UBAP1-MVB12-associated (UMA) domain containing 1
novel transcript
chrX_-_63785510 0.22 ENST00000437457.6
ENST00000374878.5
ENST00000623517.3
Cdc42 guanine nucleotide exchange factor 9
chr2_+_201132769 0.22 ENST00000494258.5
CASP8 and FADD like apoptosis regulator
chr15_+_76336755 0.22 ENST00000290759.9
ISL LIM homeobox 2
chr9_-_71121596 0.21 ENST00000377110.9
ENST00000377111.8
ENST00000677713.2
transient receptor potential cation channel subfamily M member 3
chrX_-_71254106 0.21 ENST00000373984.7
ENST00000314425.9
ENST00000373982.5
zinc finger MYM-type containing 3
chrX_+_71254781 0.21 ENST00000677446.1
non-POU domain containing octamer binding
chr3_-_169869833 0.20 ENST00000523069.1
ENST00000264676.9
ENST00000316428.10
leucine rich repeat containing 31
chr6_+_151239951 0.20 ENST00000402676.7
A-kinase anchoring protein 12
chrX_-_103502853 0.20 ENST00000372633.1
RAB40A, member RAS oncogene family
chr3_+_129440082 0.20 ENST00000347300.6
ENST00000296266.7
intraflagellar transport 122
chr6_+_27147094 0.20 ENST00000377459.3
H2A clustered histone 12
chr6_-_15586006 0.20 ENST00000462989.6
dystrobrevin binding protein 1
chr12_-_56221701 0.20 ENST00000615206.4
ENST00000549038.5
ENST00000552244.5
ring finger protein 41
chr22_+_35299800 0.19 ENST00000456128.5
ENST00000411850.5
ENST00000425375.5
ENST00000449058.7
target of myb1 membrane trafficking protein
chr7_+_134646845 0.19 ENST00000344924.8
bisphosphoglycerate mutase
chr2_+_201132928 0.19 ENST00000462763.5
CASP8 and FADD like apoptosis regulator
chr3_-_15798184 0.18 ENST00000624145.3
ankyrin repeat domain 28
chrX_-_57910458 0.18 ENST00000358697.6
zinc finger X-linked duplicated A
chr2_-_2326378 0.18 ENST00000647618.1
myelin transcription factor 1 like
chr15_+_43777078 0.18 ENST00000381359.5
small EDRK-rich factor 2
chr1_-_686673 0.17 ENST00000332831.4
olfactory receptor family 4 subfamily F member 16
chr12_-_56221909 0.17 ENST00000394013.6
ENST00000345093.9
ENST00000551711.5
ENST00000552656.5
ring finger protein 41
chr7_+_134646798 0.17 ENST00000418040.5
ENST00000393132.2
bisphosphoglycerate mutase
chr12_+_56007484 0.17 ENST00000262032.9
IKAROS family zinc finger 4
chr7_-_138679045 0.17 ENST00000419765.4
SVOP like
chr2_+_201132958 0.16 ENST00000479953.6
ENST00000340870.6
CASP8 and FADD like apoptosis regulator
chr5_-_126595237 0.16 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chr19_-_57888780 0.16 ENST00000595048.5
ENST00000600634.5
ENST00000595295.1
ENST00000596604.5
ENST00000597342.5
ENST00000597807.1
zinc finger protein 814
chr7_+_100148890 0.16 ENST00000341942.9
ENST00000474141.5
ENST00000460732.5
ENST00000441173.1
ENST00000468582.5
ENST00000488241.5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr10_+_49679637 0.16 ENST00000374113.3
ENST00000374111.8
ENST00000374112.7
ENST00000535836.1
chromosome 10 open reading frame 53
chr3_+_148791058 0.16 ENST00000491148.5
carboxypeptidase B1
chr5_+_163437569 0.15 ENST00000512163.5
ENST00000393929.5
ENST00000510097.5
ENST00000340828.7
ENST00000511490.4
ENST00000510664.5
cyclin G1
chr12_-_102062079 0.15 ENST00000545679.5
WASH complex subunit 3
chr2_+_201132872 0.15 ENST00000470178.6
CASP8 and FADD like apoptosis regulator
chr12_-_102061946 0.15 ENST00000240079.11
WASH complex subunit 3
chr5_-_126595185 0.15 ENST00000510111.6
ENST00000635851.1
ENST00000637964.1
ENST00000413020.6
ENST00000637782.1
ENST00000409134.8
ENST00000637272.1
ENST00000636879.1
ENST00000636743.1
ENST00000636886.1
ENST00000509270.2
aldehyde dehydrogenase 7 family member A1
chr21_+_25639251 0.15 ENST00000480456.6
junctional adhesion molecule 2
chr11_-_34916310 0.14 ENST00000395787.4
APAF1 interacting protein
chr2_-_264024 0.14 ENST00000403712.6
ENST00000356150.10
ENST00000626873.2
ENST00000405430.5
SH3 and SYLF domain containing 1
chr2_+_44168866 0.14 ENST00000282412.9
ENST00000409432.7
ENST00000378551.6
ENST00000345249.8
protein phosphatase, Mg2+/Mn2+ dependent 1B
chr22_+_31754862 0.14 ENST00000382111.6
ENST00000645407.1
ENST00000646701.1
DEP domain containing 5, GATOR1 subcomplex subunit
novel protein, DEPDC5-YWHAH readthrough
chr12_-_54259531 0.14 ENST00000550411.5
ENST00000439541.6
chromobox 5
chr7_-_138663152 0.14 ENST00000288513.9
SVOP like
chr10_-_30999469 0.14 ENST00000538351.6
zinc finger protein 438
chr2_-_2326210 0.14 ENST00000647755.1
myelin transcription factor 1 like
chr3_+_159839847 0.14 ENST00000445224.6
schwannomin interacting protein 1
chr12_-_76423256 0.13 ENST00000546946.5
oxysterol binding protein like 8
chr22_+_42079688 0.13 ENST00000331479.4
single-pass membrane protein with aspartate rich tail 1
chr5_-_134367070 0.13 ENST00000521118.5
cyclin dependent kinase like 3
chr4_-_139084289 0.13 ENST00000510408.5
ENST00000379549.7
ENST00000358635.7
E74 like ETS transcription factor 2
chrX_-_66033664 0.13 ENST00000427538.5
V-set and immunoglobulin domain containing 4
chr3_+_129440196 0.12 ENST00000507564.5
ENST00000348417.7
ENST00000504021.5
ENST00000349441.6
intraflagellar transport 122
chr2_-_99301195 0.12 ENST00000308528.9
lysozyme g1
chr9_-_21482313 0.12 ENST00000448696.4
interferon epsilon
chr2_+_169069537 0.12 ENST00000428522.5
ENST00000450153.1
ENST00000674881.1
ENST00000421653.5
dehydrogenase/reductase 9
chr5_+_43603163 0.12 ENST00000660752.1
ENST00000654405.1
ENST00000344920.9
ENST00000657172.1
ENST00000512996.6
ENST00000671668.1
nicotinamide nucleotide transhydrogenase
chr21_+_25639272 0.12 ENST00000400532.5
ENST00000312957.9
junctional adhesion molecule 2
chr6_+_36871841 0.12 ENST00000359359.6
chromosome 6 open reading frame 89
chr16_-_30534819 0.12 ENST00000395094.3
zinc finger protein 747
chr4_+_83035159 0.12 ENST00000509317.5
ENST00000264389.7
ENST00000503682.5
ENST00000511653.1
COP9 signalosome subunit 4
chr21_-_33641721 0.12 ENST00000399442.1
ENST00000413017.2
ENST00000445393.5
ENST00000417979.5
ENST00000381554.8
ENST00000426935.5
ENST00000381540.7
ENST00000361534.6
crystallin zeta like 1
chr1_+_146949314 0.12 ENST00000617844.4
ENST00000611443.4
NBPF member 12
chr5_-_134367144 0.12 ENST00000265334.9
cyclin dependent kinase like 3
chr10_-_27981805 0.12 ENST00000673512.1
ENST00000672877.1
ENST00000480504.1
outer dynein arm docking complex subunit 2
chr1_-_114780624 0.11 ENST00000060969.6
ENST00000369528.9
suppressor of IKBKE 1
chr19_-_5903703 0.11 ENST00000586349.5
ENST00000585661.1
ENST00000592634.5
ENST00000418389.6
ENST00000308961.5
novel protein
NADH:ubiquinone oxidoreductase subunit A11
chr5_+_43602648 0.11 ENST00000505678.6
ENST00000512422.5
ENST00000264663.9
ENST00000670904.1
ENST00000653251.1
nicotinamide nucleotide transhydrogenase
chr11_+_95790659 0.11 ENST00000538658.5
centrosomal protein 57
chr19_-_38847423 0.11 ENST00000647557.1
heterogeneous nuclear ribonucleoprotein L
chr19_+_57746799 0.11 ENST00000317178.10
ENST00000431353.1
zinc finger protein 776
chr7_-_7640971 0.10 ENST00000396682.6
replication protein A3
chr2_-_241686712 0.10 ENST00000445261.5
deoxythymidylate kinase
chr4_-_151226427 0.10 ENST00000304527.8
ENST00000409598.8
SH3 domain containing 19
chr1_+_24556087 0.10 ENST00000374392.3
non-compact myelin associated protein
chr19_-_57889004 0.10 ENST00000597832.5
ENST00000435989.7
ENST00000614383.1
zinc finger protein 814
chr4_+_119135825 0.09 ENST00000307128.6
myozenin 2
chr11_-_31509569 0.09 ENST00000526776.5
inner mitochondrial membrane peptidase subunit 1
chr6_-_110415539 0.09 ENST00000368923.8
ENST00000368924.9
D-aspartate oxidase
chr12_+_21372899 0.09 ENST00000240652.8
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chr6_+_151240368 0.09 ENST00000253332.5
A-kinase anchoring protein 12
chr21_+_42893280 0.09 ENST00000354250.7
NADH:ubiquinone oxidoreductase subunit V3
chr3_+_52536593 0.09 ENST00000307106.3
ENST00000477703.6
ENST00000476842.1
small integral membrane protein 4
chr12_-_9733083 0.09 ENST00000542530.5
C-type lectin like 1
chr6_+_83067655 0.08 ENST00000237163.9
ENST00000349129.7
DOP1 leucine zipper like protein A
chr17_+_45161864 0.08 ENST00000589230.6
ENST00000591576.5
ENST00000591070.6
ENST00000592695.1
HEXIM P-TEFb complex subunit 2
chr9_-_14307928 0.08 ENST00000637640.1
ENST00000493697.1
ENST00000636057.1
nuclear factor I B
chr17_-_42676980 0.08 ENST00000587627.1
ENST00000591022.6
ENST00000293349.10
pleckstrin homology, MyTH4 and FERM domain containing H3
chr17_-_61591192 0.08 ENST00000521764.3
nascent polypeptide associated complex subunit alpha 2
chr1_-_100895132 0.08 ENST00000535414.5
exostosin like glycosyltransferase 2
chr3_-_187670385 0.08 ENST00000287641.4
somatostatin
chr5_-_179618032 0.08 ENST00000519033.5
heterogeneous nuclear ribonucleoprotein H1
chr2_+_264869 0.07 ENST00000272067.10
ENST00000407983.7
acid phosphatase 1
chr2_+_264913 0.07 ENST00000439645.6
ENST00000405233.5
ENST00000272065.10
acid phosphatase 1
chr4_+_174918400 0.07 ENST00000404450.8
ENST00000514159.1
ADAM metallopeptidase domain 29
chr16_+_16390834 0.07 ENST00000344087.4
nuclear pore complex interacting protein family member A7
chr11_-_2140967 0.07 ENST00000381389.5
insulin like growth factor 2
chr18_+_41955186 0.07 ENST00000639914.1
ENST00000262039.9
ENST00000398870.7
ENST00000586545.5
ENST00000585528.5
phosphatidylinositol 3-kinase catalytic subunit type 3
chr16_+_69187125 0.07 ENST00000336278.8
syntrophin beta 2
chr3_+_159852933 0.07 ENST00000482804.1
schwannomin interacting protein 1
chr19_-_49451793 0.07 ENST00000262265.10
PIH1 domain containing 1
chr14_+_99684283 0.07 ENST00000261835.8
cytochrome P450 family 46 subfamily A member 1
chr16_+_19067639 0.07 ENST00000568985.5
ENST00000566110.5
coenzyme Q7, hydroxylase
chr3_+_136862254 0.06 ENST00000476286.1
ENST00000488930.5
NCK adaptor protein 1
chr2_-_88128049 0.06 ENST00000393750.3
ENST00000295834.8
fatty acid binding protein 1
chr11_-_31509588 0.06 ENST00000534812.5
ENST00000529749.5
ENST00000532287.6
ENST00000278200.5
ENST00000530023.5
ENST00000533642.1
inner mitochondrial membrane peptidase subunit 1
chr2_+_201071984 0.06 ENST00000237889.9
ENST00000433898.5
ENST00000684175.1
ENST00000682325.1
ENST00000454214.1
ENST00000684420.1
NADH:ubiquinone oxidoreductase subunit B3
chr16_+_19067893 0.06 ENST00000544894.6
ENST00000561858.5
coenzyme Q7, hydroxylase
chr2_-_27663594 0.06 ENST00000337768.10
ENST00000405491.5
ENST00000464789.2
ENST00000406540.5
SPT7 like, STAGA complex subunit gamma
chr2_+_79185231 0.06 ENST00000466387.5
catenin alpha 2
chr6_+_167291329 0.06 ENST00000366829.2
unc-93 homolog A
chr1_-_153922901 0.06 ENST00000634401.1
ENST00000368655.5
GATA zinc finger domain containing 2B
chr4_+_174918355 0.06 ENST00000505141.5
ENST00000359240.7
ENST00000615367.4
ENST00000445694.5
ENST00000618444.1
ADAM metallopeptidase domain 29
chr17_+_8288637 0.06 ENST00000407006.8
ENST00000226105.11
ENST00000580434.5
ENST00000439238.3
RAN guanine nucleotide release factor
chr14_+_22516273 0.06 ENST00000390510.1
T cell receptor alpha joining 27
chr3_-_150546403 0.06 ENST00000239944.7
ENST00000491660.1
ENST00000487153.1
stress associated endoplasmic reticulum protein 1
chr1_+_203494114 0.05 ENST00000367222.7
opticin
chr11_+_95790459 0.05 ENST00000325486.9
ENST00000325542.10
ENST00000544522.5
ENST00000541365.5
centrosomal protein 57
chr15_-_43776956 0.05 ENST00000319359.8
elongation factor for RNA polymerase II 3
chr5_+_69217798 0.05 ENST00000512880.5
ENST00000602380.1
mitochondrial ribosomal protein S36
chrX_+_141589700 0.05 ENST00000370518.4
SPANX family member A2
chr17_+_4948252 0.05 ENST00000520221.5
enolase 3
chr5_-_42825884 0.05 ENST00000506577.5
selenoprotein P
chr15_+_34345865 0.05 ENST00000333756.4
NUT midline carcinoma family member 1
chr13_+_114314474 0.05 ENST00000463003.2
ENST00000645174.1
ENST00000361283.4
ENST00000644294.1
chromosome alignment maintaining phosphoprotein 1
chr12_+_48328980 0.05 ENST00000335017.1
H1.7 linker histone
chr16_+_19067606 0.05 ENST00000321998.10
coenzyme Q7, hydroxylase
chr19_+_15082211 0.05 ENST00000641398.1
olfactory receptor family 1 subfamily I member 1
chr2_-_153478753 0.05 ENST00000325926.4
reprimo, TP53 dependent G2 arrest mediator homolog
chr19_-_50637939 0.05 ENST00000338916.8
synaptotagmin 3
chr2_+_112275588 0.05 ENST00000409871.6
ENST00000343936.4
zinc finger CCCH-type containing 6
chr2_-_27663817 0.05 ENST00000404798.6
SPT7 like, STAGA complex subunit gamma
chr19_-_39391137 0.05 ENST00000595564.5
PAF1 homolog, Paf1/RNA polymerase II complex component
chrX_+_120604084 0.05 ENST00000371317.10
MCTS1 re-initiation and release factor
chr14_+_49598761 0.05 ENST00000318317.8
leucine rich repeat protein 1
chr15_+_77420880 0.04 ENST00000336216.9
ENST00000558176.1
high mobility group 20A
chr10_+_61662921 0.04 ENST00000648843.3
ENST00000330194.2
ENST00000389639.3
ciliary associated calcium binding coiled-coil 1
chr11_+_31816266 0.04 ENST00000644607.1
ENST00000646221.1
ENST00000643671.1
ENST00000643931.1
ENST00000642614.1
ENST00000642818.1
ENST00000645848.1
ENST00000506388.2
ENST00000645824.1
ENST00000532942.5
PAX6 upstream antisense RNA
novel protein
chr10_-_24706622 0.04 ENST00000680286.1
Rho GTPase activating protein 21
chr12_-_21501551 0.04 ENST00000421138.6
ENST00000539672.1
ENST00000542432.5
ENST00000444129.7
ENST00000536964.5
ENST00000536240.5
ENST00000396093.7
ENST00000314748.10
RecQ like helicase
chrX_+_56563569 0.04 ENST00000338222.7
ubiquilin 2
chrX_-_149505274 0.04 ENST00000428056.6
ENST00000340855.11
ENST00000370441.8
iduronate 2-sulfatase
chr2_+_233032672 0.04 ENST00000233840.3
neuraminidase 2
chr3_-_120742506 0.04 ENST00000273375.8
ENST00000483733.1
RAB, member of RAS oncogene family like 3
chr16_-_20352707 0.04 ENST00000396134.6
ENST00000573567.5
ENST00000570757.5
ENST00000396138.9
ENST00000571174.5
ENST00000576688.2
uromodulin
chr2_+_180980347 0.04 ENST00000602959.5
ENST00000602479.5
ENST00000392415.6
ENST00000602291.5
ubiquitin conjugating enzyme E2 E3
chrM_-_14669 0.04 ENST00000361681.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
chr6_-_36757380 0.04 ENST00000393189.2
copine 5
chr22_+_39960397 0.04 ENST00000424496.2
novel protein similar to translation machinery associated 7 homolog (S. cerevisiae) TMA7
chr14_+_103715767 0.04 ENST00000311141.7
zinc finger FYVE-type containing 21
chr19_-_39391029 0.04 ENST00000221265.8
PAF1 homolog, Paf1/RNA polymerase II complex component
chr21_+_42893265 0.04 ENST00000340344.4
NADH:ubiquinone oxidoreductase subunit V3
chr2_-_96857984 0.04 ENST00000393537.5
ankyrin repeat domain 39
chr11_-_18526885 0.04 ENST00000251968.4
ENST00000536719.5
tumor susceptibility 101
chr1_+_198638968 0.04 ENST00000348564.11
ENST00000530727.5
ENST00000442510.8
ENST00000645247.1
ENST00000367367.8
ENST00000367364.5
ENST00000413409.6
protein tyrosine phosphatase receptor type C
chrX_+_46837034 0.04 ENST00000218340.4
RP2 activator of ARL3 GTPase
chr3_+_136862200 0.04 ENST00000288986.6
ENST00000481752.6
ENST00000491539.5
ENST00000485096.5
NCK adaptor protein 1
chr3_+_158110052 0.04 ENST00000295930.7
ENST00000471994.5
ENST00000482822.3
ENST00000476899.6
ENST00000683899.1
ENST00000684604.1
ENST00000682164.1
ENST00000464171.5
ENST00000611884.5
ENST00000312179.10
ENST00000475278.6
arginine and serine rich coiled-coil 1
chr11_-_104164361 0.04 ENST00000302251.9
platelet derived growth factor D
chr6_-_26250625 0.04 ENST00000618052.2
H3 clustered histone 7
chr18_-_14132423 0.03 ENST00000589498.5
ENST00000590202.3
zinc finger protein 519
chr3_+_156142962 0.03 ENST00000471742.5
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr18_-_50819982 0.03 ENST00000398439.8
ENST00000431965.6
ENST00000436348.6
maestro
chrX_+_151176582 0.03 ENST00000218316.4
G protein-coupled receptor 50

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 2.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.7 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.4 GO:0021593 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.1 0.3 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.3 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 1.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.3 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 1.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.7 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.3 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.5 GO:1904304 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.1 0.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.4 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0046077 dUDP biosynthetic process(GO:0006227) dTDP biosynthetic process(GO:0006233) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dTDP metabolic process(GO:0046072) dUDP metabolic process(GO:0046077)
0.0 0.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.0 0.5 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.0 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.0 GO:2000397 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.0 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.0 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.0 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.0 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.0 0.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.1 2.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0035375 zymogen binding(GO:0035375)
0.1 0.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.2 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.4 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004798 thymidylate kinase activity(GO:0004798)
0.0 0.5 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 1.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.0 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.1 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling