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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for POU2F2_POU3F1

Z-value: 1.41

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Transcription factors associated with POU2F2_POU3F1

Gene Symbol Gene ID Gene Info
ENSG00000028277.21 POU class 2 homeobox 2
ENSG00000185668.8 POU class 3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F2hg38_v1_chr19_-_42132465_421324800.561.5e-01Click!
POU3F1hg38_v1_chr1_-_38046785_38046802-0.393.4e-01Click!

Activity profile of POU2F2_POU3F1 motif

Sorted Z-values of POU2F2_POU3F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_26124161 1.84 ENST00000377791.4
ENST00000602637.1
H2A clustered histone 6
chrX_-_24647091 1.29 ENST00000356768.8
phosphate cytidylyltransferase 1, choline, beta
chr9_-_137302264 1.08 ENST00000356628.4
NOTCH regulated ankyrin repeat protein
chrX_-_24647300 1.02 ENST00000379144.7
phosphate cytidylyltransferase 1, choline, beta
chr18_-_55422306 0.85 ENST00000566777.5
ENST00000626584.2
transcription factor 4
chr18_-_55422492 0.83 ENST00000561992.5
ENST00000630712.2
transcription factor 4
chr7_+_18496162 0.79 ENST00000406072.5
histone deacetylase 9
chr7_+_16753731 0.76 ENST00000262067.5
tetraspanin 13
chr1_+_206557157 0.74 ENST00000577571.5
Ras association domain family member 5
chr6_+_37170133 0.70 ENST00000373509.6
Pim-1 proto-oncogene, serine/threonine kinase
chr6_-_27132750 0.69 ENST00000607124.1
ENST00000339812.3
H2B clustered histone 11
chr17_-_49764123 0.69 ENST00000240364.7
ENST00000506156.1
family with sequence similarity 117 member A
chr6_-_26123910 0.67 ENST00000314332.5
ENST00000396984.1
H2B clustered histone 4
chr1_-_228457855 0.66 ENST00000366695.3
H2A.W histone
chr12_-_31326111 0.64 ENST00000539409.5
SIN3-HDAC complex associated factor
chr6_+_26183750 0.64 ENST00000614097.3
H2B clustered histone 6
chr1_-_149842736 0.64 ENST00000369159.2
H2A clustered histone 18
chr22_+_32354885 0.63 ENST00000397468.5
ret finger protein like 3
chr6_+_26251607 0.62 ENST00000619466.2
H2B clustered histone 9
chr16_-_30096170 0.61 ENST00000566134.5
ENST00000565110.5
ENST00000398841.6
ENST00000398838.8
yippee like 3
chr1_+_149851053 0.61 ENST00000607355.2
H2A clustered histone 19
chr6_-_11778781 0.60 ENST00000414691.8
ENST00000229583.9
androgen dependent TFPI regulating protein
chr12_-_31326142 0.57 ENST00000337682.9
SIN3-HDAC complex associated factor
chr6_-_27146841 0.56 ENST00000356950.2
H2B clustered histone 12
chr1_-_149886652 0.56 ENST00000369155.3
H2B clustered histone 21
chr19_+_17747698 0.54 ENST00000594202.5
ENST00000252771.11
FCH and mu domain containing endocytic adaptor 1
chr5_+_145937793 0.54 ENST00000511217.1
SH3 domain containing ring finger 2
chr4_+_40192949 0.54 ENST00000507851.5
ENST00000615577.4
ENST00000613272.4
ras homolog family member H
chr2_-_112836702 0.54 ENST00000416750.1
ENST00000263341.7
ENST00000418817.5
interleukin 1 beta
chr10_-_96271508 0.53 ENST00000427367.6
ENST00000413476.6
ENST00000371176.6
B cell linker
chr19_+_17747737 0.52 ENST00000600676.5
ENST00000600209.5
ENST00000596309.5
ENST00000598539.5
ENST00000597474.5
ENST00000593385.5
ENST00000598067.5
ENST00000593833.5
FCH and mu domain containing endocytic adaptor 1
chr9_-_122228845 0.48 ENST00000394319.8
ENST00000340587.7
LIM homeobox 6
chr12_-_31326171 0.45 ENST00000542983.1
SIN3-HDAC complex associated factor
chr10_-_96271553 0.44 ENST00000224337.10
B cell linker
chr2_+_206939515 0.43 ENST00000272852.4
carboxypeptidase O
chr6_-_99349647 0.43 ENST00000389677.6
failed axon connections homolog, metaxin like GST domain containing
chr5_+_36608146 0.42 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr4_-_185812209 0.41 ENST00000393523.6
ENST00000393528.7
ENST00000449407.6
sorbin and SH3 domain containing 2
chr1_-_23559490 0.41 ENST00000374561.6
inhibitor of DNA binding 3, HLH protein
chr8_+_55879818 0.39 ENST00000520220.6
ENST00000519728.6
LYN proto-oncogene, Src family tyrosine kinase
chrX_+_70455093 0.38 ENST00000542398.1
discs large MAGUK scaffold protein 3
chr1_-_149812359 0.38 ENST00000369167.2
ENST00000545683.1
H2B clustered histone 18
chr7_-_41703062 0.38 ENST00000242208.5
inhibin subunit beta A
chr1_+_5992639 0.38 ENST00000666163.1
ENST00000671676.1
ENST00000658883.1
ENST00000445501.6
ENST00000668706.1
ENST00000653262.1
ENST00000389632.9
ENST00000341524.6
ENST00000462676.3
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr12_-_84911178 0.38 ENST00000681688.1
solute carrier family 6 member 15
chr6_-_10415043 0.36 ENST00000379613.10
transcription factor AP-2 alpha
chr12_+_107318395 0.35 ENST00000420571.6
ENST00000280758.10
BTB domain containing 11
chr16_+_33009175 0.35 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr19_+_17226597 0.35 ENST00000597836.5
occludin/ELL domain containing 1
chr17_+_7650916 0.35 ENST00000250111.9
ATPase Na+/K+ transporting subunit beta 2
chr1_+_156149657 0.35 ENST00000414683.5
semaphorin 4A
chr6_+_27247690 0.34 ENST00000421826.6
ENST00000230582.8
serine protease 16
chr17_-_7404039 0.34 ENST00000576017.1
ENST00000302422.4
transmembrane protein 256
chr6_+_27865308 0.34 ENST00000613174.2
H2A clustered histone 16
chr21_-_30829755 0.34 ENST00000621162.1
keratin associated protein 7-1
chr19_-_1132208 0.34 ENST00000438103.6
strawberry notch homolog 2
chr12_+_112907006 0.34 ENST00000680455.1
ENST00000551241.6
ENST00000550689.2
ENST00000679841.1
ENST00000679494.1
ENST00000553185.2
2'-5'-oligoadenylate synthetase 1
chr19_+_17226662 0.33 ENST00000598068.5
occludin/ELL domain containing 1
chr19_-_14884761 0.33 ENST00000642123.1
olfactory receptor family 7 subfamily A member 17
chr12_+_112906949 0.32 ENST00000679971.1
ENST00000675868.2
ENST00000550883.2
ENST00000553152.2
ENST00000202917.10
ENST00000679467.1
ENST00000680659.1
ENST00000540589.3
ENST00000552526.2
ENST00000681228.1
ENST00000680934.1
ENST00000681700.1
ENST00000679987.1
2'-5'-oligoadenylate synthetase 1
chr6_-_11779606 0.31 ENST00000506810.1
androgen dependent TFPI regulating protein
chr12_+_112906777 0.31 ENST00000452357.7
ENST00000445409.7
2'-5'-oligoadenylate synthetase 1
chr6_+_26158115 0.30 ENST00000377777.5
ENST00000289316.2
H2B clustered histone 5
chr19_+_17226218 0.30 ENST00000601529.5
ENST00000215061.9
ENST00000600232.5
occludin/ELL domain containing 1
chr17_-_58417547 0.30 ENST00000577716.5
ring finger protein 43
chr17_-_58417521 0.30 ENST00000584437.5
ENST00000407977.7
ring finger protein 43
chr1_+_156150008 0.30 ENST00000355014.6
semaphorin 4A
chr6_-_33711717 0.29 ENST00000374214.3
ubiquinol-cytochrome c reductase complex assembly factor 2
chr17_-_48817217 0.29 ENST00000393382.8
tubulin tyrosine ligase like 6
chr14_+_64540734 0.29 ENST00000247207.7
heat shock protein family A (Hsp70) member 2
chr11_+_64318091 0.28 ENST00000265462.9
ENST00000352435.8
ENST00000347941.4
peroxiredoxin 5
chr11_-_95231046 0.27 ENST00000416495.6
ENST00000536441.7
sestrin 3
chr3_+_50155305 0.27 ENST00000002829.8
ENST00000426511.5
semaphorin 3F
chr7_-_100586119 0.27 ENST00000310300.11
leucine rich repeats and calponin homology domain containing 4
chr16_-_33845229 0.27 ENST00000569103.2
immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr3_+_151873634 0.27 ENST00000362032.6
succinate receptor 1
chr14_-_106165730 0.26 ENST00000390604.2
immunoglobulin heavy variable 3-16 (non-functional)
chr6_-_10414985 0.26 ENST00000466073.5
ENST00000498450.3
transcription factor AP-2 alpha
chr11_+_34621065 0.26 ENST00000257831.8
ETS homologous factor
chr10_+_104353820 0.26 ENST00000369704.8
cilia and flagella associated protein 58
chr14_-_106154113 0.25 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr3_+_50155024 0.25 ENST00000414301.5
ENST00000450338.5
ENST00000413852.5
semaphorin 3F
chr17_+_75525682 0.25 ENST00000392550.8
ENST00000167462.9
ENST00000375227.8
ENST00000578363.5
ENST00000579392.5
LLGL scribble cell polarity complex component 2
chr6_+_27147094 0.25 ENST00000377459.3
H2A clustered histone 12
chr10_+_24239181 0.24 ENST00000438429.5
KIAA1217
chr1_+_167329044 0.24 ENST00000367862.9
POU class 2 homeobox 1
chr6_-_81752671 0.24 ENST00000320172.11
ENST00000369754.7
ENST00000369756.3
terminal nucleotidyltransferase 5A
chr6_-_33711684 0.24 ENST00000374231.8
ENST00000607484.6
ubiquinol-cytochrome c reductase complex assembly factor 2
chr4_-_86101922 0.24 ENST00000472236.5
ENST00000641881.1
mitogen-activated protein kinase 10
chr6_+_26272923 0.24 ENST00000377733.4
H2B clustered histone 10
chr2_+_89851723 0.23 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr4_-_40515967 0.23 ENST00000381795.10
RNA binding motif protein 47
chr18_-_63644250 0.23 ENST00000341074.10
ENST00000436264.1
serpin family B member 4
chr12_-_7092422 0.22 ENST00000543835.5
ENST00000647956.2
ENST00000535233.6
complement C1r
chr14_-_106389858 0.22 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr2_+_85429448 0.22 ENST00000651736.1
SH2 domain containing 6
chr1_-_153094521 0.22 ENST00000368750.8
small proline rich protein 2E
chr22_-_28711931 0.22 ENST00000434810.5
ENST00000456369.5
checkpoint kinase 2
chr19_-_49640092 0.21 ENST00000246792.4
RAS related
chr4_-_47981535 0.21 ENST00000402813.9
cyclic nucleotide gated channel subunit alpha 1
chr14_-_106557465 0.21 ENST00000390625.3
immunoglobulin heavy variable 3-49
chr12_-_56934403 0.21 ENST00000293502.2
short chain dehydrogenase/reductase family 9C member 7
chr14_-_33951052 0.21 ENST00000250457.9
ENST00000547327.2
egl-9 family hypoxia inducible factor 3
chr11_-_64317528 0.21 ENST00000308774.6
ENST00000544844.6
tRNA methyltransferase subunit 11-2
chr19_+_3572971 0.21 ENST00000453933.5
ENST00000262949.7
high mobility group 20B
chr3_-_165837412 0.21 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
butyrylcholinesterase
chr1_-_154859841 0.21 ENST00000361147.8
potassium calcium-activated channel subfamily N member 3
chr19_+_19033575 0.21 ENST00000392335.6
ENST00000537263.5
ENST00000540707.5
ENST00000535612.6
ENST00000541725.5
ENST00000269932.10
ENST00000546344.5
ENST00000540792.5
ENST00000536098.5
ENST00000541898.5
armadillo repeat containing 6
chr6_-_170291053 0.21 ENST00000366756.4
delta like canonical Notch ligand 1
chr19_+_3572777 0.21 ENST00000416526.5
high mobility group 20B
chr9_+_133459965 0.20 ENST00000540581.5
ENST00000542192.5
ENST00000291722.11
ENST00000316948.9
calcium channel flower domain containing 1
chr19_-_19170248 0.20 ENST00000410050.5
ENST00000424583.7
ENST00000409224.5
ENST00000409447.2
myocyte enhancer factor 2B
chr7_-_141973773 0.20 ENST00000547270.1
taste 2 receptor member 38
chr11_-_62601818 0.20 ENST00000278823.7
metastasis associated 1 family member 2
chr12_-_10909562 0.19 ENST00000390677.2
taste 2 receptor member 13
chr2_+_90069662 0.19 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr3_-_129688691 0.19 ENST00000432054.6
transmembrane and coiled-coil domain family 1
chr1_+_81306096 0.19 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
adhesion G protein-coupled receptor L2
chr9_-_113303271 0.19 ENST00000297894.5
ENST00000489339.2
ring finger protein 183
chr1_-_94121105 0.19 ENST00000649773.1
ENST00000370225.4
ATP binding cassette subfamily A member 4
chr16_+_23835946 0.19 ENST00000321728.12
ENST00000643927.1
protein kinase C beta
chr19_-_43619591 0.19 ENST00000598676.1
ENST00000300811.8
zinc finger protein 428
chr2_+_90021567 0.18 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr2_+_201182873 0.18 ENST00000360132.7
caspase 10
chr12_-_48570046 0.18 ENST00000301046.6
ENST00000549817.1
lactalbumin alpha
chr6_+_26216928 0.18 ENST00000303910.4
H2A clustered histone 8
chr22_+_22818994 0.18 ENST00000390316.2
immunoglobulin lambda variable 3-9
chr6_-_27807916 0.18 ENST00000377401.3
H2B clustered histone 13
chr18_-_77127935 0.17 ENST00000581878.5
myelin basic protein
chr6_+_27808163 0.17 ENST00000358739.4
H2A clustered histone 13
chr1_+_149886906 0.17 ENST00000331380.4
H2A clustered histone 20
chr1_+_17249088 0.17 ENST00000375460.3
peptidyl arginine deiminase 3
chr6_-_26216673 0.17 ENST00000541790.3
H2B clustered histone 8
chrX_+_38801451 0.17 ENST00000378474.3
ENST00000336949.7
MID1 interacting protein 1
chrX_+_38801417 0.17 ENST00000614558.2
ENST00000457894.5
MID1 interacting protein 1
chr1_+_228458095 0.17 ENST00000620438.1
H2B.U histone 1
chr6_-_142945160 0.17 ENST00000367603.8
HIVEP zinc finger 2
chrX_-_85379659 0.17 ENST00000262753.9
POF1B actin binding protein
chr18_-_55322215 0.16 ENST00000457482.7
transcription factor 4
chr22_+_22704265 0.16 ENST00000390307.2
immunoglobulin lambda variable 3-22
chr7_+_16526824 0.16 ENST00000401542.3
leucine rich repeat containing 72
chr8_-_42501224 0.16 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr18_-_55585773 0.16 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
transcription factor 4
chr6_-_142945028 0.16 ENST00000012134.7
HIVEP zinc finger 2
chr11_+_34621109 0.16 ENST00000450654.6
ETS homologous factor
chr2_+_90172802 0.15 ENST00000390277.3
immunoglobulin kappa variable 3D-11
chr1_-_201115372 0.15 ENST00000458416.2
achaete-scute family bHLH transcription factor 5
chr6_+_27893411 0.15 ENST00000616182.2
H2B clustered histone 17
chr15_+_65045377 0.15 ENST00000334287.3
solute carrier family 51 subunit beta
chr11_-_76206407 0.15 ENST00000621122.1
ENST00000322563.8
Wnt family member 11
chr2_+_173354820 0.15 ENST00000347703.7
ENST00000410101.7
ENST00000410019.3
ENST00000306721.8
cell division cycle associated 7
chr11_+_112175526 0.15 ENST00000532612.5
ENST00000438022.5
beta-carotene oxygenase 2
chr6_+_138773747 0.14 ENST00000617445.5
coiled-coil domain containing 28A
chr6_+_27133032 0.14 ENST00000359193.3
H2A clustered histone 11
chr14_-_106737547 0.14 ENST00000632209.1
immunoglobulin heavy variable 1-69-2
chr5_-_36301883 0.14 ENST00000502994.5
ENST00000515759.5
ENST00000296604.8
RAN binding protein 3 like
chr6_+_27815010 0.14 ENST00000621112.2
H2B clustered histone 14
chr11_+_112176364 0.14 ENST00000526088.5
ENST00000532593.5
ENST00000531169.5
beta-carotene oxygenase 2
chr18_-_55321986 0.14 ENST00000570287.6
transcription factor 4
chr12_-_95548213 0.14 ENST00000537435.2
ubiquitin specific peptidase 44
chr17_+_40062810 0.14 ENST00000584985.5
ENST00000264637.8
thyroid hormone receptor alpha
chr4_-_86357722 0.13 ENST00000641341.1
ENST00000642038.1
ENST00000641116.1
ENST00000641767.1
ENST00000639242.1
ENST00000638313.1
mitogen-activated protein kinase 10
chr8_-_33513077 0.13 ENST00000360742.9
ENST00000523305.1
ENST00000431156.7
ENST00000613904.1
TELO2 interacting protein 2
chr4_-_99321362 0.13 ENST00000625860.2
ENST00000305046.13
ENST00000506651.5
alcohol dehydrogenase 1B (class I), beta polypeptide
chr19_+_42284020 0.13 ENST00000160740.7
capicua transcriptional repressor
chr3_+_132317399 0.13 ENST00000475741.5
ENST00000336375.10
ENST00000351273.11
acid phosphatase 3
chr12_-_10723307 0.13 ENST00000279550.11
ENST00000228251.9
Y-box binding protein 3
chr18_-_55321640 0.13 ENST00000637169.2
transcription factor 4
chr4_+_183905266 0.13 ENST00000308497.9
storkhead box 2
chr17_-_10804092 0.13 ENST00000581851.1
transmembrane protein 238 like
chr12_-_100262356 0.12 ENST00000548313.5
DEP domain containing 4
chr2_+_219279330 0.12 ENST00000425450.5
ENST00000392086.8
ENST00000421532.5
ENST00000336576.10
DnaJ heat shock protein family (Hsp40) member B2
chr19_+_40799425 0.12 ENST00000593972.1
egl-9 family hypoxia inducible factor 2
chr19_-_40285395 0.12 ENST00000424901.5
ENST00000578123.5
AKT serine/threonine kinase 2
chr6_+_43171260 0.12 ENST00000265354.6
serum response factor
chr2_-_88979016 0.12 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr6_+_31620701 0.12 ENST00000376033.3
ENST00000376007.8
proline rich coiled-coil 2A
chr6_-_127900958 0.12 ENST00000434358.3
ENST00000630369.2
ENST00000368248.4
thymocyte selection associated
chr2_+_90234809 0.12 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr2_-_2324323 0.11 ENST00000648339.1
ENST00000647694.1
myelin transcription factor 1 like
chr12_+_80716906 0.11 ENST00000228644.4
myogenic factor 5
chr20_+_62238541 0.11 ENST00000644775.1
ENST00000645442.1
ENST00000643412.1
ENST00000644702.1
oxysterol binding protein like 2
chr16_+_85611401 0.11 ENST00000405402.6
Gse1 coiled-coil protein
chr12_-_50222694 0.11 ENST00000552783.5
LIM domain and actin binding 1
chr18_+_46946821 0.11 ENST00000245121.9
ENST00000356157.12
katanin catalytic subunit A1 like 2
chr8_+_19939246 0.11 ENST00000650287.1
lipoprotein lipase
chr11_-_11353241 0.11 ENST00000528848.3
casein kinase 2 alpha 3
chr2_-_88947820 0.11 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr10_-_102120246 0.11 ENST00000425280.2
LIM domain binding 1
chr5_-_2751648 0.11 ENST00000382611.10
iroquois homeobox 2
chr2_+_90209873 0.11 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr13_-_99016034 0.11 ENST00000448493.7
dedicator of cytokinesis 9
chr6_+_148342759 0.11 ENST00000367467.8
SAM and SH3 domain containing 1
chr19_+_35358460 0.11 ENST00000327809.5
free fatty acid receptor 3
chr12_+_19205294 0.11 ENST00000424268.5
pleckstrin homology domain containing A5
chr1_-_10472475 0.10 ENST00000377036.2
ENST00000377038.8
DNA fragmentation factor subunit alpha
chr12_-_11022620 0.10 ENST00000390673.2
taste 2 receptor member 19
chr15_+_67548992 0.10 ENST00000354498.9
mitogen-activated protein kinase kinase 5
chr1_-_216805367 0.10 ENST00000360012.7
estrogen related receptor gamma
chr18_-_55423757 0.10 ENST00000675707.1
transcription factor 4

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 0.5 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2 0.6 GO:0003409 optic cup structural organization(GO:0003409)
0.1 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0070662 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) mast cell proliferation(GO:0070662)
0.1 1.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.4 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.3 GO:0016122 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.1 0.3 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.5 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 0.2 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.2 GO:0070476 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.3 GO:0071105 response to interleukin-11(GO:0071105)
0.1 0.2 GO:1990009 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.1 0.2 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 0.2 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.7 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 0.8 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.2 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.2 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.0 0.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.0 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.2 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.2 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.4 GO:0009449 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735) negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.5 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.4 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.5 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.0 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.4 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.7 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0021678 third ventricle development(GO:0021678)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.3 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.4 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.0 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.4 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.4 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.3 GO:0072687 CatSper complex(GO:0036128) meiotic spindle(GO:0072687)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.0 GO:0071752 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 2.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 1.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.0 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.4 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.2 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.2 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.2 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.0 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.0 GO:0019862 IgA binding(GO:0019862)
0.0 0.0 GO:0005137 interleukin-5 receptor binding(GO:0005137)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 2.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha