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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for PPARA

Z-value: 0.27

Motif logo

Transcription factors associated with PPARA

Gene Symbol Gene ID Gene Info
ENSG00000186951.16 peroxisome proliferator activated receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PPARAhg38_v1_chr22_+_46150590_461506220.811.5e-02Click!

Activity profile of PPARA motif

Sorted Z-values of PPARA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_184337591 0.31 ENST00000383847.7
family with sequence similarity 131 member A
chr15_+_59438149 0.30 ENST00000288228.10
ENST00000559628.5
ENST00000557914.5
ENST00000560474.5
family with sequence similarity 81 member A
chr3_-_142029108 0.27 ENST00000497579.5
transcription factor Dp-2
chr16_+_3654683 0.27 ENST00000246949.10
deoxyribonuclease 1
chr10_+_102419189 0.25 ENST00000432590.5
F-box and leucine rich repeat protein 15
chr8_-_107498041 0.25 ENST00000297450.7
angiopoietin 1
chr8_-_107497909 0.24 ENST00000517746.6
angiopoietin 1
chr4_-_158173042 0.23 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr20_+_59577463 0.22 ENST00000359926.7
phosphatase and actin regulator 3
chr14_-_21537206 0.22 ENST00000614342.1
spalt like transcription factor 2
chr1_-_156705764 0.22 ENST00000621784.4
ENST00000368220.1
cellular retinoic acid binding protein 2
chr22_+_20774092 0.22 ENST00000215727.10
serpin family D member 1
chrX_+_136148440 0.21 ENST00000627383.2
ENST00000630084.2
four and a half LIM domains 1
chr20_+_59604527 0.20 ENST00000371015.6
phosphatase and actin regulator 3
chr8_-_92103217 0.20 ENST00000615601.4
ENST00000523629.5
RUNX1 partner transcriptional co-repressor 1
chr20_-_44187153 0.19 ENST00000372980.4
junctophilin 2
chrX_+_22136552 0.19 ENST00000682888.1
ENST00000684356.1
phosphate regulating endopeptidase homolog X-linked
chr4_-_158173004 0.19 ENST00000585682.6
golgi associated kinase 1B
chr8_+_103819244 0.18 ENST00000262231.14
ENST00000507740.5
ENST00000408894.6
regulating synaptic membrane exocytosis 2
chr14_-_103522696 0.18 ENST00000553878.5
ENST00000348956.7
ENST00000557530.1
creatine kinase B
chr9_+_12693327 0.18 ENST00000388918.10
tyrosinase related protein 1
chrX_-_21758097 0.17 ENST00000379494.4
small muscle protein X-linked
chr14_-_21098848 0.17 ENST00000556174.5
ENST00000554478.5
ENST00000553980.1
ENST00000421093.6
zinc finger protein 219
chr6_+_89080739 0.17 ENST00000369472.1
ENST00000336032.4
proline rich nuclear receptor coactivator 1
chrX_-_31266857 0.17 ENST00000378702.8
ENST00000361471.8
dystrophin
chr1_-_23559490 0.17 ENST00000374561.6
inhibitor of DNA binding 3, HLH protein
chr6_+_125203639 0.17 ENST00000392482.6
TPD52 like 1
chr3_+_189631373 0.16 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chr16_-_4538469 0.16 ENST00000588381.1
ENST00000563332.6
cell death inducing p53 target 1
chr7_+_129368123 0.16 ENST00000460109.5
ENST00000474594.5
adenosylhomocysteinase like 2
chr22_+_46762617 0.16 ENST00000380995.5
ENST00000337137.9
ENST00000407381.7
TBC1 domain family member 22A
chr1_+_212565334 0.16 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chr10_+_110497898 0.16 ENST00000369583.4
dual specificity phosphatase 5
chr16_+_641792 0.16 ENST00000307650.9
ENST00000629534.2
MAPK regulated corepressor interacting protein 2
chr17_+_75979211 0.16 ENST00000397640.6
ENST00000588202.5
ENST00000590676.1
ENST00000586891.1
TEN1 subunit of CST complex
chr17_-_31297231 0.15 ENST00000247271.5
oligodendrocyte myelin glycoprotein
chr12_-_52926459 0.15 ENST00000552150.5
keratin 8
chr3_+_179604785 0.15 ENST00000611971.4
ENST00000493866.5
ENST00000259037.8
ENST00000472629.5
ENST00000482604.5
NADH:ubiquinone oxidoreductase subunit B5
chr6_-_33580229 0.15 ENST00000374467.4
ENST00000442998.6
ENST00000360661.9
BCL2 antagonist/killer 1
chr2_+_229922482 0.15 ENST00000283946.8
ENST00000409992.1
F-box protein 36
chr17_+_40062810 0.15 ENST00000584985.5
ENST00000264637.8
thyroid hormone receptor alpha
chr4_+_15469865 0.14 ENST00000515124.6
ENST00000512702.6
ENST00000503292.6
ENST00000424120.6
ENST00000507954.5
ENST00000514450.3
ENST00000503658.2
coiled-coil and C2 domain containing 2A
chr14_-_21098570 0.14 ENST00000360947.8
zinc finger protein 219
chr22_+_46762677 0.14 ENST00000355704.7
TBC1 domain family member 22A
chr8_+_85209213 0.14 ENST00000520225.1
E2F transcription factor 5
chr19_+_1205761 0.14 ENST00000326873.12
ENST00000586243.5
serine/threonine kinase 11
chr1_+_46303646 0.14 ENST00000311672.10
ubiquinol-cytochrome c reductase hinge protein
chr16_-_4351257 0.14 ENST00000577031.5
presequence translocase associated motor 16
chr5_+_175658008 0.13 ENST00000377291.2
histamine receptor H2
chr22_-_38844020 0.13 ENST00000333039.4
neuronal pentraxin receptor
chr15_-_65422894 0.13 ENST00000352385.3
immunoglobulin superfamily DCC subclass member 4
chr19_-_48868454 0.13 ENST00000355496.9
pleckstrin homology domain containing A4
chr1_+_28887166 0.13 ENST00000347529.7
erythrocyte membrane protein band 4.1
chr1_+_184051865 0.13 ENST00000644815.1
tRNA splicing endonuclease subunit 15
chr19_-_48868590 0.13 ENST00000263265.11
pleckstrin homology domain containing A4
chr12_-_12562344 0.13 ENST00000228862.3
dual specificity phosphatase 16
chr3_-_18438767 0.13 ENST00000454909.6
SATB homeobox 1
chr16_-_1884231 0.12 ENST00000563416.3
ENST00000633813.1
ENST00000470044.5
long intergenic non-protein coding RNA 254
meiosis specific with OB-fold
chr22_-_23767876 0.12 ENST00000520222.1
ENST00000401675.7
ENST00000484558.3
coiled-coil-helix-coiled-coil-helix domain containing 10
chr6_-_41071825 0.12 ENST00000468811.5
O-acyl-ADP-ribose deacylase 1
chr12_-_12562851 0.12 ENST00000298573.9
dual specificity phosphatase 16
chrX_-_31266925 0.12 ENST00000680557.1
ENST00000378680.6
ENST00000378723.7
ENST00000680768.2
ENST00000681870.1
ENST00000680355.1
ENST00000682322.1
ENST00000682600.1
ENST00000680162.2
ENST00000681153.1
ENST00000681334.1
dystrophin
chr7_-_151736304 0.12 ENST00000492843.6
protein kinase AMP-activated non-catalytic subunit gamma 2
chr2_+_17878637 0.12 ENST00000304101.9
potassium voltage-gated channel modifier subfamily S member 3
chr15_-_90932476 0.12 ENST00000561036.1
HD domain containing 3
chr1_-_150876697 0.12 ENST00000515192.5
aryl hydrocarbon receptor nuclear translocator
chr14_+_75428011 0.12 ENST00000651602.1
ENST00000559060.5
Jun dimerization protein 2
chr1_-_46303257 0.12 ENST00000615587.4
leucine rich repeat containing 41
chr1_-_46303366 0.12 ENST00000343304.10
leucine rich repeat containing 41
chr12_+_93569814 0.12 ENST00000340600.6
suppressor of cytokine signaling 2
chr5_+_145936554 0.12 ENST00000359120.9
SH3 domain containing ring finger 2
chr12_-_16605939 0.12 ENST00000541295.5
ENST00000535535.5
LIM domain only 3
chr16_+_726936 0.12 ENST00000549114.5
ENST00000341413.8
ENST00000562187.1
ENST00000564537.5
ENST00000389703.8
hydroxyacylglutathione hydrolase like
chr11_-_707063 0.12 ENST00000683307.1
DEAF1 transcription factor
chr15_+_24954912 0.12 ENST00000584968.5
ENST00000346403.10
ENST00000554227.6
ENST00000390687.9
ENST00000579070.5
ENST00000577565.1
ENST00000577949.5
ENST00000338327.4
small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame
chr12_-_16606102 0.11 ENST00000537304.6
LIM domain only 3
chr2_-_27890348 0.11 ENST00000302188.8
ribokinase
chr16_+_727117 0.11 ENST00000562141.5
hydroxyacylglutathione hydrolase like
chr7_+_129375643 0.11 ENST00000490911.5
adenosylhomocysteinase like 2
chr2_+_10420021 0.11 ENST00000422133.1
hippocalcin like 1
chr1_-_46303589 0.11 ENST00000617190.5
leucine rich repeat containing 41
chr4_+_99574812 0.11 ENST00000422897.6
ENST00000265517.10
microsomal triglyceride transfer protein
chr19_+_35138778 0.11 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD domain containing ion transport regulator 1
novel transcript
chr11_+_57598184 0.11 ENST00000677625.1
ENST00000676670.1
serpin family G member 1
chr1_+_46175079 0.11 ENST00000372003.6
tetraspanin 1
chr18_-_58629084 0.11 ENST00000361673.4
alpha kinase 2
chr2_+_227325349 0.11 ENST00000436237.5
ENST00000443428.6
ENST00000418961.5
mitochondrial fission factor
chr6_+_139135063 0.11 ENST00000367658.3
hdc homolog, cell cycle regulator
chr1_+_184051678 0.11 ENST00000643231.1
tRNA splicing endonuclease subunit 15
chr11_-_64226129 0.11 ENST00000545812.1
ENST00000394547.7
ENST00000317459.11
tRNA phosphotransferase 1
chr16_-_66918839 0.11 ENST00000565235.2
ENST00000568632.5
ENST00000565796.5
cadherin 16
chr1_+_52142044 0.11 ENST00000287727.8
ENST00000371591.2
zinc finger FYVE-type containing 9
chr12_+_95858928 0.11 ENST00000266735.9
ENST00000553192.5
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr6_+_54307856 0.11 ENST00000370869.7
tubulointerstitial nephritis antigen
chr3_-_113746059 0.11 ENST00000477813.5
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr2_-_42493970 0.11 ENST00000394973.4
ENST00000306078.2
potassium voltage-gated channel modifier subfamily G member 3
chr1_-_145964567 0.11 ENST00000606888.3
ankyrin repeat domain 34A
chr19_-_51065067 0.10 ENST00000595547.5
ENST00000335422.3
ENST00000595793.6
ENST00000596955.1
kallikrein related peptidase 13
chr6_+_135851681 0.10 ENST00000308191.11
phosphodiesterase 7B
chr10_+_100999287 0.10 ENST00000370220.1
leucine zipper tumor suppressor 2
chr14_-_104795718 0.10 ENST00000407796.7
ENST00000649815.2
ENST00000349310.7
AKT serine/threonine kinase 1
chr16_-_66918876 0.10 ENST00000570262.5
ENST00000299752.9
ENST00000394055.7
cadherin 16
chr10_-_70376779 0.10 ENST00000395011.5
leucine rich repeat containing 20
chr2_-_175181663 0.10 ENST00000392541.3
ENST00000284727.9
ENST00000409194.5
ATP synthase membrane subunit c locus 3
chr12_-_16606795 0.10 ENST00000447609.5
LIM domain only 3
chr16_-_4351283 0.10 ENST00000318059.8
presequence translocase associated motor 16
chr11_-_64246190 0.10 ENST00000392210.6
protein phosphatase 1 regulatory inhibitor subunit 14B
chr8_-_92095627 0.10 ENST00000517919.5
ENST00000617740.4
ENST00000613302.4
ENST00000436581.6
ENST00000614812.4
ENST00000519847.5
RUNX1 partner transcriptional co-repressor 1
chr11_-_123885627 0.10 ENST00000528595.1
ENST00000375026.7
transmembrane protein 225
chr1_-_150876571 0.10 ENST00000354396.6
ENST00000358595.10
ENST00000505755.5
aryl hydrocarbon receptor nuclear translocator
chr22_+_17638584 0.10 ENST00000337612.9
ENST00000418951.6
ENST00000538149.5
ENST00000543133.5
ENST00000611738.4
ENST00000616863.4
ENST00000618481.4
ENST00000317582.10
ENST00000493680.5
BCL2 like 13
chr11_+_68030896 0.10 ENST00000525628.1
NADH:ubiquinone oxidoreductase core subunit S8
chr22_+_17638796 0.10 ENST00000355028.4
BCL2 like 13
chrX_+_70452286 0.10 ENST00000374355.7
discs large MAGUK scaffold protein 3
chr15_+_36594868 0.10 ENST00000566807.5
ENST00000643612.1
ENST00000567389.5
ENST00000562877.5
CDAN1 interacting nuclease 1
chr18_+_58863580 0.10 ENST00000586085.5
ENST00000589288.5
zinc finger protein 532
chr22_+_29767351 0.10 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr19_-_18538371 0.10 ENST00000596015.1
FKBP prolyl isomerase 8
chr4_+_41612892 0.10 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIM and calponin homology domains 1
chr6_-_159727324 0.10 ENST00000401980.3
ENST00000545162.5
superoxide dismutase 2
chr8_+_22245125 0.10 ENST00000306433.9
ENST00000519237.5
ENST00000397802.8
RNA polymerase III subunit D
chr11_-_86672419 0.10 ENST00000524826.7
ENST00000532471.1
malic enzyme 3
chr2_+_218607861 0.10 ENST00000450993.7
phospholipase C delta 4
chr4_-_121952014 0.10 ENST00000379645.8
transient receptor potential cation channel subfamily C member 3
chr1_+_236395394 0.10 ENST00000359362.6
EDAR associated death domain
chr17_-_8152380 0.10 ENST00000317276.9
period circadian regulator 1
chr1_+_145964675 0.10 ENST00000369314.2
ENST00000369313.7
RNA polymerase III subunit GL
chr16_+_85613252 0.10 ENST00000253458.12
ENST00000393243.5
Gse1 coiled-coil protein
chr17_+_81703356 0.10 ENST00000333676.8
ENST00000571730.1
mitochondrial ribosomal protein L12
novel protein
chr14_-_21023318 0.10 ENST00000298684.9
ENST00000557169.5
ENST00000553563.5
NDRG family member 2
chr9_-_35685462 0.10 ENST00000607559.1
tropomyosin 2
chr6_-_43059367 0.10 ENST00000230413.9
ENST00000487429.1
ENST00000388752.8
ENST00000489623.1
ENST00000468957.1
mitochondrial ribosomal protein L2
chr3_-_179071432 0.09 ENST00000414084.1
zinc finger matrin-type 3
chr11_-_86672114 0.09 ENST00000393324.7
malic enzyme 3
chr2_+_218270392 0.09 ENST00000248451.7
ENST00000273077.9
PNKD metallo-beta-lactamase domain containing
chr11_-_8810635 0.09 ENST00000527510.5
ENST00000528527.5
ENST00000313726.11
ENST00000528523.5
DENN domain containing 2B
chr8_+_144095054 0.09 ENST00000318911.5
cytochrome c1
chr9_-_127874964 0.09 ENST00000373156.5
adenylate kinase 1
chr1_+_19596960 0.09 ENST00000617872.4
ENST00000322753.7
ENST00000602662.1
mitochondrial contact site and cristae organizing system subunit 10
NBL1, DAN family BMP antagonist
chr1_-_154974361 0.09 ENST00000368453.8
ENST00000368450.5
SHC adaptor protein 1
chr2_-_210315160 0.09 ENST00000352451.4
myosin light chain 1
chr14_+_36657560 0.09 ENST00000402703.6
paired box 9
chr12_+_55973913 0.09 ENST00000553116.5
RAB5B, member RAS oncogene family
chr17_-_75848641 0.09 ENST00000586257.5
WW domain binding protein 2
chr15_+_65045377 0.09 ENST00000334287.3
solute carrier family 51 subunit beta
chr9_-_128127711 0.09 ENST00000449878.1
ENST00000338961.11
ENST00000678174.1
prostaglandin E synthase 2
chr10_+_68560317 0.09 ENST00000373644.5
tet methylcytosine dioxygenase 1
chr17_-_55732074 0.09 ENST00000575734.5
transmembrane protein 100
chr1_+_42682388 0.09 ENST00000321358.12
ENST00000332220.10
Y-box binding protein 1
chr5_+_86617967 0.09 ENST00000515763.1
cytochrome c oxidase subunit 7C
chr8_-_126558461 0.09 ENST00000304916.4
LRAT domain containing 2
chr2_+_233307806 0.09 ENST00000447536.5
ENST00000409110.6
S-antigen visual arrestin
chr2_+_218607914 0.09 ENST00000417849.5
phospholipase C delta 4
chr14_+_88385714 0.09 ENST00000045347.11
spermatogenesis associated 7
chr9_+_113536497 0.09 ENST00000462143.5
regulator of G protein signaling 3
chr1_-_156816738 0.09 ENST00000368198.7
SH2 domain containing 2A
chr12_+_55974059 0.09 ENST00000360299.10
ENST00000548068.5
ENST00000549915.5
ENST00000551459.5
ENST00000448789.2
RAB5B, member RAS oncogene family
chr1_-_205935822 0.09 ENST00000340781.8
solute carrier family 26 member 9
chr19_-_2328573 0.09 ENST00000587502.2
ENST00000252622.15
ENST00000585409.2
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr16_-_30526518 0.09 ENST00000380412.7
zinc finger protein 768
chr16_-_30526758 0.09 ENST00000562803.1
zinc finger protein 768
chr2_+_33476640 0.09 ENST00000425210.5
ENST00000444784.5
ENST00000423159.5
ENST00000403687.8
RAS guanyl releasing protein 3
chr17_-_63842663 0.09 ENST00000613943.4
ENST00000448276.7
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr14_-_49586325 0.09 ENST00000557519.1
ENST00000396020.7
ENST00000554075.2
ENST00000245458.11
ribosomal protein S29
chr5_+_86617919 0.09 ENST00000247655.4
ENST00000509578.1
cytochrome c oxidase subunit 7C
chr6_+_33204645 0.09 ENST00000374662.4
hydroxysteroid 17-beta dehydrogenase 8
chr1_+_165827574 0.09 ENST00000367879.9
uridine-cytidine kinase 2
chr1_-_156816841 0.09 ENST00000368199.8
ENST00000392306.2
SH2 domain containing 2A
chr11_+_65638085 0.08 ENST00000534313.6
ENST00000533361.1
ENST00000526137.1
signal-induced proliferation-associated 1
chr10_-_73874461 0.08 ENST00000305762.11
calcium/calmodulin dependent protein kinase II gamma
chr19_+_17309531 0.08 ENST00000359866.9
DET1 and DDB1 associated 1
chrX_-_110440218 0.08 ENST00000372057.1
ENST00000372054.3
AMMECR nuclear protein 1
G protein subunit gamma 5 pseudogene 2
chr1_+_206684887 0.08 ENST00000367103.4
ENST00000294981.8
MAPK activated protein kinase 2
chr1_-_205750167 0.08 ENST00000367142.5
nuclear casein kinase and cyclin dependent kinase substrate 1
chr1_+_184051696 0.08 ENST00000533373.6
ENST00000647437.1
ENST00000647465.1
ENST00000645668.2
ENST00000645963.2
tRNA splicing endonuclease subunit 15
chr4_-_86357722 0.08 ENST00000641341.1
ENST00000642038.1
ENST00000641116.1
ENST00000641767.1
ENST00000639242.1
ENST00000638313.1
mitogen-activated protein kinase 10
chr12_-_22334683 0.08 ENST00000404299.3
ENST00000396037.9
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr3_-_114624979 0.08 ENST00000676079.1
zinc finger and BTB domain containing 20
chr2_+_46297397 0.08 ENST00000263734.5
endothelial PAS domain protein 1
chr15_+_75043263 0.08 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr12_+_93570381 0.08 ENST00000549206.5
suppressor of cytokine signaling 2
chr6_+_143677935 0.08 ENST00000440869.6
ENST00000367582.7
ENST00000451827.6
phosphatase and actin regulator 2
chr11_+_64230726 0.08 ENST00000321460.5
DnaJ heat shock protein family (Hsp40) member C4
chr19_-_45639104 0.08 ENST00000586770.5
ENST00000591721.5
ENST00000245925.8
ENST00000590043.5
ENST00000589876.5
EMAP like 2
chr2_+_176157293 0.08 ENST00000683222.1
homeobox D3
chr19_+_1407731 0.08 ENST00000592453.2
DAZ associated protein 1
chr17_-_1649854 0.08 ENST00000301336.7
Rab interacting lysosomal protein
chr17_-_43022350 0.08 ENST00000587173.5
ENST00000355653.8
vesicle amine transport 1
chr1_+_32765667 0.08 ENST00000373480.1
KIAA1522
chr14_-_21024092 0.08 ENST00000554398.5
NDRG family member 2
chr14_-_22957100 0.08 ENST00000555367.5
HAUS augmin like complex subunit 4
chr4_-_13484313 0.08 ENST00000330852.10
ENST00000288723.9
ENST00000338176.8
ENST00000630951.1
RAB28, member RAS oncogene family
chr17_+_42288464 0.08 ENST00000590726.7
ENST00000678903.1
ENST00000590949.6
ENST00000676585.1
ENST00000588868.5
signal transducer and activator of transcription 5A
chr1_-_173917281 0.08 ENST00000367698.4
serpin family C member 1
chr16_-_695946 0.08 ENST00000562563.1
F-box and leucine rich repeat protein 16
chr1_+_6034980 0.08 ENST00000378092.6
ENST00000472700.7
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr14_-_22957061 0.08 ENST00000557591.5
ENST00000541587.6
ENST00000490506.5
ENST00000554406.1
HAUS augmin like complex subunit 4
chr11_-_64226218 0.08 ENST00000394546.6
ENST00000541278.5
tRNA phosphotransferase 1
chr11_+_64226266 0.08 ENST00000279206.8
ENST00000441250.6
nudix hydrolase 22
chr14_-_22957128 0.08 ENST00000342454.12
ENST00000555986.5
ENST00000554516.5
ENST00000347758.6
ENST00000206474.11
ENST00000555040.5
HAUS augmin like complex subunit 4

Network of associatons between targets according to the STRING database.

First level regulatory network of PPARA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.1 0.2 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.3 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.2 GO:0002339 B cell selection(GO:0002339)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.2 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.1 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:2000984 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.0 0.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.6 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:1904045 cellular response to aldosterone(GO:1904045)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.1 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:0051695 actin filament uncapping(GO:0051695)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.1 GO:0018013 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.1 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.1 GO:0001315 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0036304 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027) negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.0 GO:1904253 circadian temperature homeostasis(GO:0060086) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.1 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.2 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0090301 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.0 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.0 GO:0044335 canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.0 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.0 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.2 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0051801 cytolysis in other organism involved in symbiotic interaction(GO:0051801) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:1990879 CST complex(GO:1990879)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.0 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.2 GO:0008893 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity(GO:0008893) diphosphoric monoester hydrolase activity(GO:0016794)
0.1 0.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.3 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.0 GO:0000035 acyl binding(GO:0000035)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.0 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.0 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling