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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for PPARG

Z-value: 0.83

Motif logo

Transcription factors associated with PPARG

Gene Symbol Gene ID Gene Info
ENSG00000132170.24 peroxisome proliferator activated receptor gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PPARGhg38_v1_chr3_+_12289061_122890800.591.2e-01Click!

Activity profile of PPARG motif

Sorted Z-values of PPARG motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_49513154 0.99 ENST00000426395.7
ENST00000600273.5
ENST00000599988.5
Fc fragment of IgG receptor and transporter
chr5_+_157269317 0.87 ENST00000618329.4
cytoplasmic FMR1 interacting protein 2
chr1_+_203305510 0.61 ENST00000290551.5
BTG anti-proliferation factor 2
chr15_+_32718476 0.60 ENST00000652365.1
gremlin 1, DAN family BMP antagonist
chr16_+_8674605 0.57 ENST00000268251.13
4-aminobutyrate aminotransferase
chr15_+_32717994 0.55 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
gremlin 1, DAN family BMP antagonist
chr5_+_32710630 0.54 ENST00000326958.5
natriuretic peptide receptor 3
chr11_+_117200188 0.53 ENST00000529792.5
transgelin
chr8_+_69492793 0.53 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
sulfatase 1
chr11_+_308408 0.53 ENST00000399815.2
novel protein
chrX_-_52069172 0.49 ENST00000486010.1
ENST00000497164.5
ENST00000360134.10
ENST00000485287.5
ENST00000335504.9
MAGE family member D4B
chr19_+_49513353 0.48 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr3_-_146251136 0.48 ENST00000493382.5
ENST00000383083.6
phospholipid scramblase 4
chr14_+_24161257 0.48 ENST00000396864.8
ENST00000557894.5
ENST00000559284.5
ENST00000560275.5
interferon regulatory factor 9
chr3_-_146251068 0.44 ENST00000433593.6
ENST00000476202.5
ENST00000354952.7
ENST00000460885.5
phospholipid scramblase 4
chr11_-_74311609 0.44 ENST00000331597.9
ENST00000427714.2
prolyl 4-hydroxylase subunit alpha 3
chrX_+_136169891 0.44 ENST00000449474.5
four and a half LIM domains 1
chr1_+_170664121 0.44 ENST00000239461.11
paired related homeobox 1
chr22_+_30881674 0.43 ENST00000454145.5
ENST00000453621.5
ENST00000431368.5
ENST00000535268.5
oxysterol binding protein 2
chr12_+_53046969 0.42 ENST00000379902.7
tensin 2
chr11_+_308106 0.42 ENST00000399817.9
ENST00000680344.1
interferon induced transmembrane protein 2
chr11_+_314010 0.42 ENST00000680699.1
ENST00000681938.1
ENST00000679380.1
ENST00000680938.1
ENST00000408968.4
ENST00000681180.1
ENST00000681426.1
ENST00000680696.1
interferon induced transmembrane protein 1
chrX_-_107716401 0.41 ENST00000486554.1
ENST00000372390.8
TSC22 domain family member 3
chr11_+_308188 0.41 ENST00000680619.1
ENST00000681833.1
ENST00000680261.1
interferon induced transmembrane protein 2
chr11_+_308217 0.41 ENST00000602569.2
interferon induced transmembrane protein 2
chr19_+_35138993 0.41 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr4_-_1668905 0.40 ENST00000461064.5
family with sequence similarity 53 member A
chr22_-_24245059 0.39 ENST00000398292.3
ENST00000263112.11
ENST00000327365.10
ENST00000424217.1
gamma-glutamyltransferase 5
chr17_+_50095285 0.39 ENST00000503614.5
pyruvate dehydrogenase kinase 2
chr3_+_69763726 0.38 ENST00000448226.9
melanocyte inducing transcription factor
chr16_+_21663968 0.37 ENST00000646100.2
otoancorin
chr3_+_69763549 0.37 ENST00000472437.5
melanocyte inducing transcription factor
chr14_+_104745960 0.36 ENST00000556623.1
ENST00000555674.1
adenylosuccinate synthase 1
chr16_+_55479188 0.35 ENST00000219070.9
matrix metallopeptidase 2
chr19_+_4343696 0.35 ENST00000597036.5
MPN domain containing
chr11_-_64284639 0.35 ENST00000394532.7
ENST00000394531.3
ENST00000309032.8
BCL2 associated agonist of cell death
chr6_-_52577012 0.35 ENST00000182527.4
translocation associated membrane protein 2
chr17_+_50095331 0.33 ENST00000503176.6
pyruvate dehydrogenase kinase 2
chr14_+_100381974 0.32 ENST00000542471.2
WD repeat domain 25
chrX_+_154144242 0.32 ENST00000369951.9
opsin 1, long wave sensitive
chr12_-_120446372 0.32 ENST00000546954.2
TP53 regulated inhibitor of apoptosis 1
chr19_-_10334723 0.31 ENST00000592945.1
intercellular adhesion molecule 3
chr1_-_30908681 0.30 ENST00000339394.7
syndecan 3
chr19_-_40257045 0.30 ENST00000578615.6
AKT serine/threonine kinase 2
chrX_+_52184904 0.30 ENST00000375626.7
ENST00000467526.1
MAGE family member D4
chr2_+_30146941 0.29 ENST00000379520.7
ENST00000379519.7
yippee like 5
chrX_+_9543103 0.29 ENST00000683056.1
transducin beta like 1 X-linked
chr2_+_30146993 0.29 ENST00000261353.9
ENST00000402003.7
yippee like 5
chr19_+_4343587 0.29 ENST00000596722.5
MPN domain containing
chr7_+_120988683 0.28 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr9_+_137225166 0.28 ENST00000650725.2
cysteine rich tail 1
chr17_+_41819201 0.28 ENST00000455106.1
FKBP prolyl isomerase 10
chr1_-_46176482 0.28 ENST00000540385.2
ENST00000506599.2
P3R3URF-PIK3R3 readthrough
PIK3R3 upstream reading frame
chrX_+_103607906 0.27 ENST00000243286.7
ENST00000372627.10
transcription elongation factor A like 3
chr16_+_20901059 0.27 ENST00000396052.3
LYR motif containing 1
chr14_+_20999255 0.27 ENST00000554422.5
ENST00000298681.5
solute carrier family 39 member 2
chr11_+_117199363 0.26 ENST00000392951.9
ENST00000525531.5
ENST00000278968.10
transgelin
chr13_-_27450544 0.26 ENST00000381116.5
ENST00000381120.8
mitochondrial translational initiation factor 3
chr11_-_1750558 0.26 ENST00000340134.5
interferon induced transmembrane protein 10
chr19_+_4343527 0.26 ENST00000262966.12
ENST00000359935.8
ENST00000599840.6
MPN domain containing
chr16_+_981762 0.26 ENST00000293894.4
SRY-box transcription factor 8
chr16_+_20900753 0.26 ENST00000219168.8
ENST00000567954.6
LYR motif containing 1
chr2_+_112138359 0.26 ENST00000331203.7
ENST00000409903.5
ENST00000409667.7
ENST00000409450.7
fibulin 7
chr17_+_47209375 0.26 ENST00000572303.1
myosin light chain 4
chr22_+_22343185 0.26 ENST00000427632.2
immunoglobulin lambda variable 9-49
chr3_+_9917074 0.25 ENST00000416074.6
ENST00000383812.9
ENST00000438091.5
ENST00000295981.7
ENST00000403601.8
ENST00000436503.5
ENST00000455057.5
interleukin 17 receptor C
chr9_+_121286115 0.25 ENST00000477104.2
ENST00000394353.7
gelsolin
chr7_+_76303547 0.25 ENST00000429938.1
heat shock protein family B (small) member 1
chr8_-_96235533 0.25 ENST00000518406.5
ENST00000287022.10
ENST00000523920.1
ubiquinol-cytochrome c reductase binding protein
chr14_+_105486867 0.25 ENST00000409393.6
ENST00000392531.4
cysteine rich protein 1
chr10_+_91162958 0.24 ENST00000614189.4
polycomb group ring finger 5
chr19_+_45864318 0.24 ENST00000302177.3
forkhead box A3
chr22_-_23980469 0.24 ENST00000404092.5
novel protein, AP000351.4-DDT readtrhough
chrX_+_54920796 0.24 ENST00000442098.5
ENST00000430420.5
ENST00000453081.5
ENST00000319167.12
ENST00000622017.4
ENST00000375022.8
ENST00000399736.5
ENST00000440072.5
ENST00000173898.12
ENST00000431115.5
ENST00000440759.5
ENST00000375041.6
trophinin
chr10_+_133379238 0.24 ENST00000357296.7
ENST00000278060.10
polyamine oxidase
chr14_+_105486311 0.23 ENST00000330233.11
cysteine rich protein 1
chr19_-_49640092 0.23 ENST00000246792.4
RAS related
chr11_+_2902388 0.23 ENST00000380574.5
solute carrier family 22 member 18
chr6_-_73452124 0.23 ENST00000680833.1
cyclic GMP-AMP synthase
chr15_+_57706725 0.23 ENST00000380557.4
ENST00000649091.1
RNA polymerase II subunit M
chr19_+_35138778 0.23 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD domain containing ion transport regulator 1
novel transcript
chr8_-_100105955 0.23 ENST00000523437.5
regulator of G protein signaling 22
chr2_-_42361198 0.23 ENST00000234301.3
cytochrome c oxidase subunit 7A2 like
chr8_-_100106034 0.22 ENST00000360863.11
ENST00000617334.1
regulator of G protein signaling 22
chr15_+_57706670 0.22 ENST00000299638.8
RNA polymerase II subunit M
chr6_-_43510686 0.22 ENST00000372441.1
leucine rich repeat containing 73
chr3_+_48466222 0.22 ENST00000625293.3
ENST00000492235.2
ENST00000635452.2
ENST00000456089.1
three prime repair exonuclease 1
chr1_+_61203496 0.22 ENST00000663597.1
nuclear factor I A
chr15_-_88546585 0.22 ENST00000649547.1
ENST00000558413.1
ENST00000564406.5
ENST00000268148.13
novel transcript
DET1 partner of COP1 E3 ubiquitin ligase
chr19_+_52369911 0.22 ENST00000424032.6
ENST00000422689.3
ENST00000600321.5
ENST00000344085.9
ENST00000597976.5
zinc finger protein 880
chr3_+_48465811 0.21 ENST00000433541.1
ENST00000444177.1
three prime repair exonuclease 1
chr10_+_133453936 0.21 ENST00000640237.1
scavenger receptor family member expressed on T cells 1
chr8_-_100336184 0.21 ENST00000519527.5
ENST00000522369.5
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr22_-_29766934 0.21 ENST00000344318.4
zinc finger matrin-type 5
chr15_-_40039140 0.21 ENST00000559081.1
signal recognition particle 14
chr2_+_230996115 0.21 ENST00000424440.5
ENST00000452881.5
ENST00000433428.6
ENST00000455816.1
ENST00000440792.5
ENST00000423134.1
spermatogenesis associated 3
chr17_-_57955242 0.21 ENST00000577840.5
CUE domain containing 1
chr9_+_34329495 0.21 ENST00000346365.8
ENST00000379155.9
ENST00000618590.1
nudix hydrolase 2
chr6_+_138773747 0.20 ENST00000617445.5
coiled-coil domain containing 28A
chr3_+_9917185 0.20 ENST00000413608.2
ENST00000451165.6
interleukin 17 receptor C
chr9_+_34329545 0.20 ENST00000379158.7
nudix hydrolase 2
chr2_-_69437588 0.20 ENST00000394305.5
NFU1 iron-sulfur cluster scaffold
chr19_+_18340581 0.20 ENST00000604499.6
ENST00000269919.11
ENST00000595066.5
ENST00000252813.5
pyroglutamyl-peptidase I
chr16_-_4800470 0.20 ENST00000592019.1
ENST00000586153.1
rogdi atypical leucine zipper
chr8_-_100105619 0.19 ENST00000523287.5
ENST00000519092.5
regulator of G protein signaling 22
chrX_-_154479253 0.19 ENST00000357360.4
L antigen family member 3
chr1_-_112704921 0.19 ENST00000414971.1
ENST00000534717.5
ras homolog family member C
chr19_+_850985 0.19 ENST00000590230.5
elastase, neutrophil expressed
chr9_-_135699473 0.19 ENST00000425225.2
ENST00000298466.9
spermatogenesis and oogenesis specific basic helix-loop-helix 1
chr4_+_41990496 0.19 ENST00000264451.12
solute carrier family 30 member 9
chr12_+_120446418 0.18 ENST00000551765.6
ENST00000229384.5
glutamyl-tRNA amidotransferase subunit C
chr1_-_159925496 0.18 ENST00000368097.9
transgelin 2
chr6_-_112254485 0.18 ENST00000521398.5
ENST00000424408.6
ENST00000243219.7
laminin subunit alpha 4
chr7_+_150801522 0.18 ENST00000461345.5
transmembrane protein 176A
chr20_+_58907981 0.18 ENST00000656419.1
GNAS complex locus
chr2_+_201129318 0.18 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr15_-_74461102 0.18 ENST00000567435.5
ENST00000564488.5
ENST00000565130.5
ENST00000563081.1
ENST00000565335.5
ENST00000395081.7
ENST00000361351.8
ubiquitin like 7
chr6_+_292050 0.18 ENST00000344450.9
dual specificity phosphatase 22
chr20_+_45934670 0.17 ENST00000372409.8
phosphorylated CTD interacting factor 1
chr1_-_111427731 0.17 ENST00000369732.4
oviductal glycoprotein 1
chr1_+_19596960 0.17 ENST00000617872.4
ENST00000322753.7
ENST00000602662.1
mitochondrial contact site and cristae organizing system subunit 10
NBL1, DAN family BMP antagonist
chr16_+_426379 0.17 ENST00000434585.5
RAB11 family interacting protein 3
chr2_-_69437417 0.17 ENST00000450796.6
ENST00000484177.5
ENST00000410022.7
ENST00000303698.7
NFU1 iron-sulfur cluster scaffold
chr5_-_178730651 0.17 ENST00000335815.7
zinc finger protein 354A
chr11_-_67443459 0.16 ENST00000341356.10
ENST00000627576.2
coronin 1B
chr10_-_31031911 0.16 ENST00000375311.1
ENST00000413025.5
ENST00000436087.6
ENST00000452305.5
ENST00000442986.5
zinc finger protein 438
chr20_+_64036175 0.16 ENST00000636176.2
chromosome 20 open reading frame 204
chr7_+_142332182 0.16 ENST00000547918.2
T cell receptor beta variable 7-1 (non-functional)
chr11_-_66026473 0.16 ENST00000312106.6
cation channel sperm associated 1
chr21_+_39445824 0.16 ENST00000380637.7
ENST00000380634.5
ENST00000458295.5
ENST00000440288.6
ENST00000380631.5
SH3 domain binding glutamate rich protein
chr1_+_201648136 0.16 ENST00000367296.8
neuron navigator 1
chr19_-_9785996 0.16 ENST00000589412.5
ENST00000586814.5
zinc finger protein 846
chr19_+_535824 0.16 ENST00000606065.3
cell division cycle 34, ubiqiutin conjugating enzyme
chr5_+_176549323 0.15 ENST00000261944.9
cadherin related family member 2
chr3_+_38496467 0.15 ENST00000453767.1
exo/endonuclease G
chr17_+_45620323 0.15 ENST00000634540.1
LINC02210-CRHR1 readthrough
chr8_-_144901414 0.15 ENST00000533221.5
ENST00000525694.5
ENST00000533622.5
ENST00000417550.7
ENST00000292579.11
zinc finger protein 250
chr7_+_150801695 0.15 ENST00000475536.5
ENST00000468689.2
transmembrane protein 176A
chr11_+_68010339 0.15 ENST00000617288.4
aldehyde dehydrogenase 3 family member B1
chr16_-_705726 0.15 ENST00000397621.6
ENST00000324361.9
F-box and leucine rich repeat protein 16
chr1_-_19484635 0.15 ENST00000433834.5
capping actin protein of muscle Z-line subunit beta
chr1_-_46941425 0.15 ENST00000371904.8
cytochrome P450 family 4 subfamily A member 11
chr22_+_22822658 0.15 ENST00000620395.2
immunoglobulin lambda variable 2-8
chr19_-_49361475 0.15 ENST00000598810.5
TEA domain transcription factor 2
chr19_+_49361783 0.15 ENST00000594268.1
dickkopf like acrosomal protein 1
chr18_+_54828406 0.15 ENST00000262094.10
RAB27B, member RAS oncogene family
chr20_+_33283205 0.15 ENST00000253354.2
BPI fold containing family B member 1
chr19_-_50513870 0.15 ENST00000389208.9
aspartate dehydrogenase domain containing
chr19_-_50837213 0.15 ENST00000326856.8
kallikrein related peptidase 15
chr16_+_57245336 0.15 ENST00000562023.5
ENST00000563234.1
ADP ribosylation factor like GTPase 2 binding protein
chr16_-_57486454 0.14 ENST00000340099.9
docking protein 4
chr1_-_114780624 0.14 ENST00000060969.6
ENST00000369528.9
suppressor of IKBKE 1
chrX_+_102125703 0.14 ENST00000329035.2
transcription elongation factor A like 2
chr16_+_57245229 0.14 ENST00000219204.8
ADP ribosylation factor like GTPase 2 binding protein
chr5_+_116084992 0.14 ENST00000274458.9
ENST00000632434.1
COMM domain containing 10
chr8_-_27992624 0.14 ENST00000524352.5
scavenger receptor class A member 5
chr3_+_8733779 0.14 ENST00000343849.3
ENST00000397368.2
caveolin 3
chr9_-_112718021 0.14 ENST00000374234.1
ENST00000374242.9
ENST00000374236.5
INTS3 and NABP interacting protein
chr3_+_49021071 0.14 ENST00000395458.6
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr19_+_35775530 0.14 ENST00000314737.9
ENST00000007510.8
Rho GTPase activating protein 33
chrX_+_102125668 0.14 ENST00000372780.6
transcription elongation factor A like 2
chr16_+_30372291 0.14 ENST00000568749.5
myosin light chain, phosphorylatable, fast skeletal muscle
chr4_-_185425941 0.14 ENST00000264689.11
ENST00000505357.1
UFM1 specific peptidase 2
chr1_-_151790475 0.14 ENST00000368825.7
ENST00000368823.5
ENST00000368824.8
ENST00000458431.6
ENST00000368827.10
ENST00000440583.6
tudor and KH domain containing
chr12_+_6828377 0.14 ENST00000290510.10
prolyl 3-hydroxylase 3
chr19_+_507487 0.14 ENST00000359315.6
tubulin polyglutamylase complex subunit 1
chr9_-_128204218 0.14 ENST00000634901.1
ENST00000372948.7
CDKN1A interacting zinc finger protein 1
chr5_+_177304571 0.13 ENST00000503853.1
PRELI domain containing 1
chr12_-_122227449 0.13 ENST00000650715.1
diablo IAP-binding mitochondrial protein
chr12_+_66189208 0.13 ENST00000261233.9
interleukin 1 receptor associated kinase 3
chr7_+_127588355 0.13 ENST00000415666.1
ENST00000000233.10
ADP ribosylation factor 5
chr17_-_43907467 0.13 ENST00000520406.5
ENST00000518478.1
ENST00000522172.5
ENST00000461854.5
ENST00000521178.5
ENST00000269095.9
ENST00000520305.5
ENST00000523501.5
ENST00000520241.5
membrane palmitoylated protein 2
chr9_+_99222258 0.13 ENST00000223641.5
SEC61 translocon subunit beta
chr15_-_40039154 0.13 ENST00000560773.5
ENST00000267884.11
signal recognition particle 14
chr19_-_43026448 0.13 ENST00000598133.1
ENST00000403486.5
ENST00000320078.12
ENST00000306322.7
pregnancy specific beta-1-glycoprotein 11
chr19_-_46846138 0.13 ENST00000597020.5
adaptor related protein complex 2 subunit sigma 1
chr17_-_50373173 0.13 ENST00000225969.9
ENST00000503633.5
ENST00000442592.3
mitochondrial ribosomal protein L27
chr9_-_21217311 0.13 ENST00000380216.1
interferon alpha 16
chrX_+_154542194 0.13 ENST00000618670.4
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chr19_+_840991 0.12 ENST00000234347.10
proteinase 3
chr11_-_1309604 0.12 ENST00000525159.5
ENST00000527938.5
ENST00000530541.1
ENST00000317204.11
ENST00000263646.11
toll interacting protein
chr4_+_140257286 0.12 ENST00000394205.7
short coiled-coil protein
chr1_-_160285120 0.12 ENST00000368072.10
peroxisomal biogenesis factor 19
chr16_+_85613252 0.12 ENST00000253458.12
ENST00000393243.5
Gse1 coiled-coil protein
chr17_-_78903193 0.12 ENST00000322630.3
ENST00000586713.5
CEP295 N-terminal like
chr3_+_38496329 0.12 ENST00000287675.10
ENST00000630638.1
ENST00000422077.6
exo/endonuclease G
chr11_+_60040402 0.12 ENST00000278855.7
ENST00000532905.1
oocyte secreted protein 2
chr9_+_137788781 0.12 ENST00000482340.5
euchromatic histone lysine methyltransferase 1
chr19_-_1479118 0.12 ENST00000436106.3
ENST00000586564.5
ENST00000592872.5
ENST00000588871.5
ENST00000588427.5
ENST00000591027.2
ENST00000585675.6
ENST00000651077.1
ENST00000427685.2
chromosome 19 open reading frame 25
chr22_+_22792485 0.12 ENST00000390314.2
immunoglobulin lambda variable 2-11
chr19_-_12957198 0.12 ENST00000316939.3
GADD45G interacting protein 1
chr17_-_28718405 0.12 ENST00000430132.6
ENST00000301043.10
ENST00000412625.5
RAB34, member RAS oncogene family
chr15_-_40038895 0.12 ENST00000558720.5
signal recognition particle 14
chr9_+_83623048 0.11 ENST00000454393.5
IDNK gluconokinase
chr17_-_36176636 0.11 ENST00000611257.5
ENST00000616006.1
TBC1 domain family member 3B
chr19_+_35775515 0.11 ENST00000378944.9
Rho GTPase activating protein 33
chr17_-_28717792 0.11 ENST00000636772.1
RAB34, member RAS oncogene family
chr6_+_33410961 0.11 ENST00000374512.7
ENST00000374516.8
PHD finger protein 1
chr15_+_69452811 0.11 ENST00000357790.5
ENST00000260379.11
ENST00000560274.1
ribosomal protein lateral stalk subunit P1
chr2_+_180980566 0.11 ENST00000410062.9
ubiquitin conjugating enzyme E2 E3

Network of associatons between targets according to the STRING database.

First level regulatory network of PPARG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.4 1.2 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.2 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.6 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 0.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.4 GO:2000078 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) positive regulation of type B pancreatic cell development(GO:2000078)
0.1 0.6 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.3 GO:1990009 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.1 0.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.5 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 0.3 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.3 GO:0072034 renal vesicle induction(GO:0072034)
0.1 0.2 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.1 0.3 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 0.2 GO:0010933 macrophage tolerance induction(GO:0010931) regulation of macrophage tolerance induction(GO:0010932) positive regulation of macrophage tolerance induction(GO:0010933)
0.1 0.2 GO:0009447 putrescine catabolic process(GO:0009447) spermidine catabolic process(GO:0046203)
0.1 1.9 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 1.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.2 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.1 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.6 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.5 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.0 0.5 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.4 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.1 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.2 GO:0046618 drug export(GO:0046618)
0.0 0.6 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.4 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.3 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.0 GO:0002434 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.3 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0051232 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0071110 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:2000410 regulation of thymocyte migration(GO:2000410)
0.0 0.2 GO:0060992 response to fungicide(GO:0060992)
0.0 0.2 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.7 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.4 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.3 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.2 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.0 GO:0035494 SNARE complex disassembly(GO:0035494)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 0.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.2 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.1 GO:0071753 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.6 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.3 GO:0016015 morphogen activity(GO:0016015)
0.1 0.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 1.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.3 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.2 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0019798 procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0036505 prosaposin receptor activity(GO:0036505)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.0 GO:0000035 acyl binding(GO:0000035)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 2.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport