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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for PRDM1

Z-value: 1.17

Motif logo

Transcription factors associated with PRDM1

Gene Symbol Gene ID Gene Info
ENSG00000057657.17 PR/SET domain 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM1hg38_v1_chr6_+_106098933_106098958-0.936.7e-04Click!

Activity profile of PRDM1 motif

Sorted Z-values of PRDM1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_101452629 1.08 ENST00000622834.4
ENST00000545560.6
ENST00000376180.8
integrin subunit beta like 1
chr8_+_96493803 1.01 ENST00000518385.5
ENST00000302190.9
syndecan 2
chr5_+_93583212 0.82 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chr11_-_27722021 0.61 ENST00000314915.6
brain derived neurotrophic factor
chr6_-_166862502 0.60 ENST00000510118.5
ENST00000503859.5
ENST00000506565.1
ribosomal protein S6 kinase A2
chr9_+_18474100 0.58 ENST00000327883.11
ENST00000431052.6
ENST00000380570.8
ENST00000380548.9
ADAMTS like 1
chr4_+_125314918 0.57 ENST00000674496.2
ENST00000394329.9
FAT atypical cadherin 4
chr3_+_69866217 0.54 ENST00000314589.10
melanocyte inducing transcription factor
chr17_+_43006740 0.51 ENST00000438323.2
ENST00000415816.7
interferon induced protein 35
chrX_-_119693150 0.49 ENST00000394610.7
septin 6
chr3_+_51943244 0.47 ENST00000498510.2
poly(ADP-ribose) polymerase family member 3
chr9_+_18474206 0.46 ENST00000276935.6
ADAMTS like 1
chr8_+_76681208 0.41 ENST00000651372.2
zinc finger homeobox 4
chrX_-_119693370 0.41 ENST00000360156.11
ENST00000354228.8
ENST00000489216.5
ENST00000354416.7
ENST00000343984.5
septin 6
chr7_-_122886706 0.41 ENST00000313070.11
ENST00000334010.11
ENST00000615869.4
calcium dependent secretion activator 2
chr2_-_223838022 0.41 ENST00000444408.1
adaptor related protein complex 1 subunit sigma 3
chr2_-_223837553 0.41 ENST00000396654.7
ENST00000396653.2
ENST00000443700.5
adaptor related protein complex 1 subunit sigma 3
chr3_+_8501846 0.40 ENST00000454244.4
LIM and cysteine rich domains 1
chr2_-_223837484 0.40 ENST00000446015.6
ENST00000409375.1
adaptor related protein complex 1 subunit sigma 3
chr3_-_49813880 0.40 ENST00000333486.4
ubiquitin like modifier activating enzyme 7
chrX_-_63754664 0.39 ENST00000677315.1
ENST00000636392.1
ENST00000637040.1
ENST00000637178.1
ENST00000637557.1
ENST00000636048.1
ENST00000638021.1
ENST00000672513.1
novel protein
Cdc42 guanine nucleotide exchange factor 9
chr15_-_37101205 0.39 ENST00000338564.9
ENST00000558313.5
ENST00000340545.9
Meis homeobox 2
chr10_-_13707536 0.38 ENST00000632570.1
ENST00000477221.2
FERM domain containing 4A
chr2_-_144517663 0.37 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
zinc finger E-box binding homeobox 2
chr4_-_99321362 0.37 ENST00000625860.2
ENST00000305046.13
ENST00000506651.5
alcohol dehydrogenase 1B (class I), beta polypeptide
chrX_-_63785510 0.35 ENST00000437457.6
ENST00000374878.5
ENST00000623517.3
Cdc42 guanine nucleotide exchange factor 9
chr8_-_115668966 0.35 ENST00000395715.8
transcriptional repressor GATA binding 1
chr4_-_137532452 0.33 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr4_+_141636923 0.31 ENST00000529613.5
interleukin 15
chr4_+_141636611 0.31 ENST00000514653.5
interleukin 15
chr3_+_8501807 0.31 ENST00000426878.2
ENST00000397386.7
ENST00000415597.5
ENST00000157600.8
LIM and cysteine rich domains 1
chrX_+_10156960 0.30 ENST00000380833.9
chloride voltage-gated channel 4
chr10_-_49539112 0.29 ENST00000355832.10
ENST00000447839.7
ERCC excision repair 6, chromatin remodeling factor
chr10_-_49539015 0.29 ENST00000681659.1
ENST00000680107.1
ERCC excision repair 6, chromatin remodeling factor
chr13_+_23570370 0.29 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr16_-_67936808 0.29 ENST00000358514.9
proteasome 20S subunit beta 10
chr4_+_141636563 0.26 ENST00000320650.9
ENST00000296545.11
interleukin 15
chr5_-_94111627 0.26 ENST00000505869.5
ENST00000395965.8
ENST00000509163.5
family with sequence similarity 172 member A
chr2_+_230327218 0.26 ENST00000243810.10
ENST00000396563.8
SP140 nuclear body protein like
chr2_+_230327160 0.26 ENST00000444636.5
ENST00000415673.7
SP140 nuclear body protein like
chr12_+_94148553 0.24 ENST00000258526.9
plexin C1
chr19_+_49474561 0.23 ENST00000594009.5
ENST00000595510.1
ENST00000595815.1
fms related receptor tyrosine kinase 3 ligand
novel transcript
chr2_+_157257687 0.23 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr9_+_2159672 0.22 ENST00000634343.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr16_+_50742059 0.22 ENST00000311559.13
ENST00000564326.5
ENST00000566206.5
ENST00000427738.8
CYLD lysine 63 deubiquitinase
chr11_+_63536801 0.22 ENST00000255688.8
ENST00000439013.6
phospholipase A and acyltransferase 4
chr7_+_95772506 0.22 ENST00000537881.5
ENST00000447467.6
ENST00000524053.5
ENST00000324972.10
ENST00000630942.2
ENST00000437599.5
ENST00000359388.8
ENST00000413338.5
dynein cytoplasmic 1 intermediate chain 1
chr3_-_114624193 0.21 ENST00000481632.5
zinc finger and BTB domain containing 20
chr14_+_24136152 0.20 ENST00000559123.5
ENST00000206451.11
ENST00000382708.7
ENST00000561435.5
proteasome activator subunit 1
chr6_+_31572279 0.20 ENST00000418386.3
lymphotoxin alpha
chr12_-_54259531 0.20 ENST00000550411.5
ENST00000439541.6
chromobox 5
chr2_+_174395721 0.20 ENST00000272732.11
ENST00000458563.5
ENST00000409673.7
ENST00000435964.1
ENST00000424069.5
ENST00000427038.5
secernin 3
chrX_+_9560465 0.19 ENST00000647060.1
transducin beta like 1 X-linked
chr3_-_64445396 0.19 ENST00000295902.11
prickle planar cell polarity protein 2
chr1_+_109910485 0.18 ENST00000525659.5
colony stimulating factor 1
chr8_-_115668609 0.18 ENST00000220888.9
transcriptional repressor GATA binding 1
chr2_-_230219902 0.17 ENST00000409815.6
SP110 nuclear body protein
chr5_+_132410832 0.17 ENST00000638452.2
ENST00000638568.2
ENST00000612967.2
ENST00000337752.6
ENST00000378947.7
ENST00000407797.6
novel protein
IRF1 antisense RNA 1
chr17_+_48831021 0.17 ENST00000509507.5
ENST00000448105.6
ENST00000570513.5
ENST00000509415.5
ENST00000513119.5
ENST00000416445.6
ENST00000508679.5
ENST00000258947.8
ENST00000505071.5
calcium binding and coiled-coil domain 2
chr22_-_36239517 0.17 ENST00000358502.10
ENST00000451256.6
apolipoprotein L2
chr9_+_134641768 0.17 ENST00000371817.8
ENST00000618395.4
collagen type V alpha 1 chain
chr3_-_71493500 0.17 ENST00000648380.1
ENST00000650295.1
forkhead box P1
chr5_+_134525649 0.16 ENST00000282605.8
ENST00000681547.2
ENST00000361895.6
ENST00000402835.5
jade family PHD finger 2
chr5_+_50666660 0.16 ENST00000515175.6
poly(ADP-ribose) polymerase family member 8
chr5_+_50666917 0.16 ENST00000514342.6
poly(ADP-ribose) polymerase family member 8
chr1_+_3069160 0.16 ENST00000511072.5
PR/SET domain 16
chr19_-_6670151 0.15 ENST00000675206.1
TNF superfamily member 14
chr11_+_71999927 0.15 ENST00000393707.4
interleukin 18 binding protein
chr3_+_185328886 0.14 ENST00000428617.1
ENST00000443863.5
mitogen-activated protein kinase kinase kinase 13
chr8_-_29263063 0.14 ENST00000524189.6
kinesin family member 13B
chr19_-_6670117 0.14 ENST00000245912.7
TNF superfamily member 14
chr13_+_108269629 0.14 ENST00000430559.5
ENST00000375887.9
TNF superfamily member 13b
chr11_+_71999603 0.14 ENST00000260049.9
interleukin 18 binding protein
chr20_+_408147 0.14 ENST00000441733.5
ENST00000353660.7
RANBP2-type and C3HC4-type zinc finger containing 1
chr4_-_53591477 0.13 ENST00000263925.8
ligand of numb-protein X 1
chr8_+_133191029 0.13 ENST00000250160.11
cellular communication network factor 4
chr10_-_80289647 0.13 ENST00000372213.8
methionine adenosyltransferase 1A
chr11_+_71998892 0.13 ENST00000393705.8
ENST00000393703.9
ENST00000337131.9
ENST00000620017.4
ENST00000531053.5
ENST00000404792.5
interleukin 18 binding protein
chr17_+_6756035 0.13 ENST00000361842.8
ENST00000574907.5
XIAP associated factor 1
chr5_+_50666950 0.13 ENST00000513738.5
ENST00000503665.5
ENST00000514067.6
ENST00000503046.5
poly(ADP-ribose) polymerase family member 8
chr6_+_32854179 0.13 ENST00000374859.3
proteasome 20S subunit beta 9
chr14_-_24146596 0.12 ENST00000560410.5
ENST00000216802.10
ENST00000615264.4
ENST00000630027.1
proteasome activator subunit 2
chr4_+_186069144 0.12 ENST00000513189.1
ENST00000296795.8
toll like receptor 3
chr5_+_50666612 0.12 ENST00000281631.10
poly(ADP-ribose) polymerase family member 8
chr14_-_24146314 0.12 ENST00000559056.5
proteasome activator subunit 2
chr6_+_57317602 0.12 ENST00000274891.10
ENST00000671770.1
ENST00000672107.1
ENST00000615550.5
DNA primase subunit 2
chr22_-_36160773 0.12 ENST00000531095.1
ENST00000349314.6
ENST00000397293.6
apolipoprotein L3
chr6_-_154510675 0.12 ENST00000607772.6
CNKSR family member 3
chr13_+_30735523 0.12 ENST00000380490.5
arachidonate 5-lipoxygenase activating protein
chr19_+_12995467 0.11 ENST00000592199.6
nuclear factor I X
chrX_-_120560947 0.11 ENST00000674137.11
ENST00000371322.11
ENST00000681090.1
cullin 4B
chr2_+_230416190 0.11 ENST00000340126.9
ENST00000432979.5
SP100 nuclear antigen
chr17_+_6755834 0.11 ENST00000346752.8
XIAP associated factor 1
chr15_-_55917080 0.10 ENST00000506154.1
NEDD4 E3 ubiquitin protein ligase
chr18_+_21363593 0.10 ENST00000580732.6
GREB1 like retinoic acid receptor coactivator
chrX_-_120560884 0.10 ENST00000404115.8
cullin 4B
chr11_+_46380746 0.10 ENST00000405308.6
midkine
chr21_-_34526850 0.10 ENST00000481448.5
ENST00000381132.6
regulator of calcineurin 1
chr17_-_28368012 0.10 ENST00000555059.2
novel protein, readthrough between VTN and SEBOX
chr7_+_134779625 0.10 ENST00000454108.5
ENST00000361675.7
caldesmon 1
chr12_+_6452024 0.10 ENST00000266556.8
ENST00000544021.5
TAP binding protein like
chr6_+_32844108 0.10 ENST00000458296.2
ENST00000413039.6
ENST00000412095.1
ENST00000395330.5
PSMB8 antisense RNA 1 (head to head)
proteasome 20S subunit beta 9
chr7_+_134779663 0.09 ENST00000361901.6
caldesmon 1
chr19_+_35748549 0.09 ENST00000301159.14
lin-37 DREAM MuvB core complex component
chr9_-_21202205 0.08 ENST00000239347.3
interferon alpha 7
chr2_+_165294031 0.08 ENST00000283256.10
sodium voltage-gated channel alpha subunit 2
chr14_-_24442662 0.08 ENST00000554698.5
short chain dehydrogenase/reductase family 39U member 1
chr3_+_63911929 0.08 ENST00000487717.5
ataxin 7
chr14_-_24442241 0.08 ENST00000555355.5
ENST00000553343.5
ENST00000556523.1
ENST00000556249.1
ENST00000538105.6
ENST00000555225.5
short chain dehydrogenase/reductase family 39U member 1
chr20_+_32358303 0.08 ENST00000651418.1
ENST00000375687.10
ENST00000542461.5
ENST00000613218.4
ENST00000646367.1
ENST00000620121.4
ASXL transcriptional regulator 1
chr16_+_50742037 0.08 ENST00000569418.5
CYLD lysine 63 deubiquitinase
chr2_+_69013170 0.08 ENST00000303714.9
ANTXR cell adhesion molecule 1
chr14_-_24442765 0.07 ENST00000555365.5
ENST00000399395.8
ENST00000553930.5
short chain dehydrogenase/reductase family 39U member 1
chr3_+_63912588 0.07 ENST00000522345.2
ataxin 7
chr10_-_34815257 0.07 ENST00000374789.8
ENST00000374788.8
ENST00000346874.9
ENST00000374794.8
ENST00000350537.9
ENST00000374790.8
ENST00000374776.6
ENST00000374773.6
ENST00000545260.5
ENST00000545693.5
ENST00000340077.9
par-3 family cell polarity regulator
chr2_-_230219944 0.07 ENST00000455674.2
ENST00000392048.7
ENST00000258381.11
ENST00000358662.9
ENST00000258382.10
SP110 nuclear body protein
chr5_+_108924585 0.07 ENST00000618353.1
FER tyrosine kinase
chr9_+_18474165 0.07 ENST00000380566.8
ADAMTS like 1
chr16_-_31074193 0.07 ENST00000300849.5
zinc finger protein 668
chr17_+_35731620 0.07 ENST00000603017.2
RAS like family 10 member B
chr15_-_55917129 0.07 ENST00000338963.6
ENST00000508342.5
NEDD4 E3 ubiquitin protein ligase
chr2_+_230416239 0.07 ENST00000409824.5
ENST00000409341.5
ENST00000409112.5
SP100 nuclear antigen
chr16_+_50742110 0.07 ENST00000566679.6
ENST00000564634.5
ENST00000398568.6
CYLD lysine 63 deubiquitinase
chr16_+_30664334 0.06 ENST00000287468.5
fibrosin
chr8_+_95133746 0.06 ENST00000315367.4
pleckstrin homology and FYVE domain containing 2
chr10_-_110918934 0.06 ENST00000605742.5
BBSome interacting protein 1
chr6_-_32843994 0.06 ENST00000395339.7
ENST00000374882.8
proteasome 20S subunit beta 8
chr3_+_119294337 0.06 ENST00000264245.9
Rho GTPase activating protein 31
chr5_+_77210881 0.06 ENST00000340978.7
ENST00000346042.7
ENST00000342343.8
ENST00000333194.8
phosphodiesterase 8B
chr6_-_33314386 0.06 ENST00000456592.3
TAP binding protein
chr5_+_77210667 0.06 ENST00000264917.10
phosphodiesterase 8B
chr15_+_70892443 0.05 ENST00000443425.6
ENST00000560369.5
leucine rich repeat containing 49
chr2_-_70248454 0.05 ENST00000416149.6
ENST00000282574.8
TIA1 cytotoxic granule associated RNA binding protein
chr20_+_13995369 0.05 ENST00000217246.8
ENST00000684519.1
ENST00000642719.1
mono-ADP ribosylhydrolase 2
chr21_-_33931607 0.05 ENST00000429238.2
novel protein similar to ATP synthase delta (OSCP) subunit domain
chr11_-_40294089 0.05 ENST00000278198.2
leucine rich repeat containing 4C
chr2_+_238848029 0.05 ENST00000448943.2
ENST00000612363.2
twist family bHLH transcription factor 2
chr6_-_28252246 0.05 ENST00000377294.3
zinc finger with KRAB and SCAN domains 4
chr1_+_27773189 0.05 ENST00000373943.9
ENST00000440806.2
syntaxin 12
chr15_+_70892809 0.05 ENST00000260382.10
ENST00000560755.5
leucine rich repeat containing 49
chr22_+_41301514 0.05 ENST00000352645.5
zinc finger CCCH-type containing 7B
chr14_-_68793055 0.05 ENST00000439696.3
ZFP36 ring finger protein like 1
chr11_+_46380932 0.04 ENST00000441869.5
midkine
chr1_-_243843226 0.04 ENST00000336199.9
AKT serine/threonine kinase 3
chr2_-_196592671 0.04 ENST00000260983.8
ENST00000644030.1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr8_-_23682889 0.04 ENST00000523261.1
ENST00000380871.5
NK3 homeobox 1
chr2_-_174395640 0.04 ENST00000342016.8
corepressor interacting with RBPJ, CIR1
chr12_+_93572664 0.04 ENST00000551556.2
suppressor of cytokine signaling 2
chr12_-_118061153 0.04 ENST00000315436.8
ENST00000544233.5
WD repeat and SOCS box containing 2
chr5_-_96808093 0.04 ENST00000296754.7
endoplasmic reticulum aminopeptidase 1
chr2_-_222298659 0.04 ENST00000336840.11
ENST00000344493.9
paired box 3
chr11_+_46381033 0.04 ENST00000359803.7
midkine
chr20_+_58651785 0.04 ENST00000358029.8
syntaxin 16
chr4_-_73223082 0.04 ENST00000509867.6
ankyrin repeat domain 17
chr15_+_78540405 0.04 ENST00000560217.5
ENST00000559082.5
ENST00000559948.5
ENST00000413382.6
ENST00000559146.5
ENST00000044462.12
ENST00000558281.5
proteasome 20S subunit alpha 4
chr2_-_201643448 0.04 ENST00000409883.7
transmembrane protein 237
chr4_-_99219230 0.03 ENST00000394897.5
ENST00000508558.1
ENST00000394899.6
alcohol dehydrogenase 6 (class V)
chr6_-_33314247 0.03 ENST00000475304.5
ENST00000489157.5
TAP binding protein
chr6_+_26156323 0.03 ENST00000304218.6
H1.4 linker histone, cluster member
chr1_+_151399557 0.03 ENST00000290541.7
proteasome 20S subunit beta 4
chr22_-_31292445 0.03 ENST00000402249.7
ENST00000215912.10
ENST00000443175.1
ENST00000441972.5
phosphoinositide-3-kinase interacting protein 1
chr5_+_141213919 0.03 ENST00000341948.6
protocadherin beta 13
chr6_-_132589686 0.03 ENST00000258034.3
trace amine associated receptor 5
chr4_+_87006988 0.03 ENST00000307808.10
AF4/FMR2 family member 1
chr6_+_108295037 0.03 ENST00000368977.9
ENST00000421954.5
AFG1 like ATPase
chr9_+_19230435 0.03 ENST00000602925.5
DENN domain containing 4C
chr2_-_222298974 0.02 ENST00000392069.6
ENST00000392070.7
paired box 3
chr7_+_135148041 0.02 ENST00000275767.3
transmembrane protein 140
chr19_+_19405655 0.02 ENST00000683918.1
GATA zinc finger domain containing 2A
chr17_+_3475959 0.02 ENST00000263080.3
aspartoacylase
chr10_+_120851341 0.02 ENST00000263461.11
WD repeat domain 11
chr12_-_52406335 0.02 ENST00000257974.3
keratin 82
chr1_-_205356894 0.02 ENST00000367155.8
kelch domain containing 8A
chr6_-_33314202 0.02 ENST00000426633.6
ENST00000467025.1
TAP binding protein
chr1_+_181033887 0.02 ENST00000684662.1
ENST00000434571.7
ENST00000367580.6
ENST00000617803.5
ENST00000683652.1
ENST00000367579.7
ENST00000282990.10
major histocompatibility complex, class I-related
chr5_-_96807899 0.02 ENST00000503921.5
ENST00000508227.5
ENST00000507154.1
ENST00000443439.7
endoplasmic reticulum aminopeptidase 1
chr7_+_128715385 0.01 ENST00000315184.9
family with sequence similarity 71 member F1
chr11_+_46381194 0.01 ENST00000533952.5
midkine
chr2_+_69013282 0.01 ENST00000409829.7
ANTXR cell adhesion molecule 1
chr8_+_133191060 0.01 ENST00000519433.1
ENST00000517423.5
ENST00000220856.6
cellular communication network factor 4
chr1_+_20633450 0.01 ENST00000321556.5
PTEN induced kinase 1
chr14_-_23010122 0.01 ENST00000397377.5
ENST00000397379.7
ENST00000341470.8
ENST00000555998.5
ENST00000299088.11
ENST00000397376.6
ENST00000553675.5
ENST00000553931.5
ENST00000555575.5
ENST00000553958.5
ENST00000555098.5
ENST00000556419.5
ENST00000553606.5
ENST00000554179.5
ENST00000397382.8
chromosome 14 open reading frame 93
chrX_-_134796256 0.01 ENST00000486347.5
PABIR family member 2
chr20_+_408030 0.01 ENST00000640614.1
ENST00000475269.5
RANBP2-type and C3HC4-type zinc finger containing 1
chrX_+_155380709 0.01 ENST00000354514.6
H2A.B variant histone 2
chr6_+_146027662 0.01 ENST00000492807.6
ENST00000361719.6
glutamate metabotropic receptor 1
chr10_+_113129285 0.01 ENST00000637574.1
transcription factor 7 like 2
chr1_+_156767526 0.01 ENST00000271526.9
proline rich mitotic checkpoint control factor
chr9_-_146140 0.01 ENST00000475990.5
COBW domain containing 1
chr1_-_151763334 0.01 ENST00000481777.5
ENST00000368829.3
ENST00000368830.8
mitochondrial ribosomal protein L9
chr22_-_30246739 0.01 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr14_+_101761786 0.00 ENST00000422945.6
ENST00000554442.5
ENST00000556260.6
ENST00000328724.9
ENST00000557268.5
protein phosphatase 2 regulatory subunit B'gamma
chr2_+_230416156 0.00 ENST00000427101.6
SP100 nuclear antigen
chr1_-_8423664 0.00 ENST00000476556.5
arginine-glutamic acid dipeptide repeats

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0045062 extrathymic T cell selection(GO:0045062)
0.2 0.6 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.2 1.0 GO:0008218 bioluminescence(GO:0008218)
0.1 0.6 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.5 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.1 0.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.2 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.1 1.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.2 GO:0019089 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.4 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0060611 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 0.2 GO:0030421 defecation(GO:0030421)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 1.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0050904 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.4 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.0 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.0 GO:1903383 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 1.1 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.2 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.4 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling