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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for RAD21_SMC3

Z-value: 0.26

Motif logo

Transcription factors associated with RAD21_SMC3

Gene Symbol Gene ID Gene Info
ENSG00000164754.15 RAD21 cohesin complex component
ENSG00000108055.10 structural maintenance of chromosomes 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMC3hg38_v1_chr10_+_110567666_1105677650.831.0e-02Click!
RAD21hg38_v1_chr8_-_116874746_1168748280.245.7e-01Click!

Activity profile of RAD21_SMC3 motif

Sorted Z-values of RAD21_SMC3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_186375671 0.48 ENST00000451586.1
translocated promoter region, nuclear basket protein
chr1_-_186375325 0.44 ENST00000613151.1
translocated promoter region, nuclear basket protein
chr7_+_90154442 0.39 ENST00000297205.7
STEAP family member 1
chr1_-_186375239 0.34 ENST00000367478.9
translocated promoter region, nuclear basket protein
chr13_+_31199959 0.32 ENST00000343307.5
beta 3-glucosyltransferase
chr22_+_31082860 0.31 ENST00000619644.4
smoothelin
chr8_+_28622729 0.29 ENST00000523149.5
exostosin like glycosyltransferase 3
chr10_-_15371225 0.27 ENST00000378116.9
family with sequence similarity 171 member A1
chr18_+_46174055 0.26 ENST00000615553.1
chromosome 18 open reading frame 25
chr15_-_34210011 0.25 ENST00000557877.5
katanin regulatory subunit B1 like 1
chr6_+_137867414 0.23 ENST00000237289.8
ENST00000433680.1
TNF alpha induced protein 3
chr1_+_186375813 0.22 ENST00000419367.8
ENST00000287859.11
ENST00000367470.8
odr-4 GPCR localization factor homolog
chr6_+_137867241 0.22 ENST00000612899.5
ENST00000420009.5
TNF alpha induced protein 3
chr5_-_137499293 0.22 ENST00000510689.5
ENST00000394945.6
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1
chr1_+_212035717 0.21 ENST00000366991.5
denticleless E3 ubiquitin protein ligase homolog
chr6_+_33391805 0.21 ENST00000428849.7
ENST00000450504.1
kinesin family member C1
chr3_-_49719668 0.21 ENST00000320431.8
adhesion molecule with Ig like domain 3
chr19_+_57830288 0.21 ENST00000442832.8
ENST00000594901.2
zinc finger protein 587B
chr17_+_36534980 0.20 ENST00000614443.2
ENST00000619326.1
phosphatidylinositol glycan anchor biosynthesis class W
chr14_+_105491226 0.19 ENST00000451719.5
ENST00000392523.9
ENST00000392522.7
ENST00000354560.10
ENST00000334656.11
ENST00000450383.1
tubulin epsilon and delta complex 1
chr5_-_140346596 0.19 ENST00000230990.7
heparin binding EGF like growth factor
chr11_+_20387681 0.19 ENST00000437750.2
ENST00000331079.11
protein arginine methyltransferase 3
chr19_-_57888780 0.18 ENST00000595048.5
ENST00000600634.5
ENST00000595295.1
ENST00000596604.5
ENST00000597342.5
ENST00000597807.1
zinc finger protein 814
chr8_+_66429003 0.18 ENST00000320270.4
ribosome biogenesis regulator 1 homolog
chr12_-_51269949 0.17 ENST00000603864.5
ENST00000605426.5
small cell adhesion glycoprotein
chr10_-_100009860 0.17 ENST00000324109.9
dynamin binding protein
chr10_-_78029487 0.17 ENST00000372371.8
RNA polymerase III subunit A
chr12_+_109900518 0.17 ENST00000312777.9
ENST00000536408.2
trichoplein keratin filament binding
chr14_+_21749163 0.17 ENST00000390427.3
T cell receptor alpha variable 5
chr5_+_138352674 0.17 ENST00000314358.10
lysine demethylase 3B
chr12_+_109900258 0.16 ENST00000405876.9
trichoplein keratin filament binding
chr19_-_3547306 0.16 ENST00000589063.5
ENST00000615073.4
major facilitator superfamily domain containing 12
chr2_+_69013282 0.16 ENST00000409829.7
ANTXR cell adhesion molecule 1
chr2_+_69013414 0.16 ENST00000681816.1
ENST00000482235.2
ANTXR cell adhesion molecule 1
chr12_+_50504970 0.15 ENST00000301180.10
disco interacting protein 2 homolog B
chr7_-_22500152 0.15 ENST00000406890.6
ENST00000678116.1
ENST00000424363.5
STEAP family member 1B
chr3_+_172750715 0.15 ENST00000392692.8
ENST00000417960.5
ENST00000428567.5
ENST00000366090.6
ENST00000426894.5
epithelial cell transforming 2
chr16_+_71358713 0.15 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
calbindin 2
chr1_+_111755892 0.15 ENST00000369702.5
ENST00000680627.1
ENST00000680518.1
DEAD-box helicase 20
chr19_+_10013468 0.15 ENST00000591589.3
retinol dehydrogenase 8
chr1_-_93909329 0.15 ENST00000370238.8
ENST00000615724.1
glutamate-cysteine ligase modifier subunit
chr4_+_55346213 0.15 ENST00000679836.1
ENST00000264228.9
ENST00000679707.1
steroid 5 alpha-reductase 3
novel protein, SRD5A3-RP11-177J6.1 readthrough
chr8_+_142727186 0.15 ENST00000336138.4
thioesterase superfamily member 6
chr3_+_172750682 0.15 ENST00000232458.9
ENST00000540509.5
epithelial cell transforming 2
chr4_+_55948871 0.14 ENST00000422247.6
ENST00000257287.5
centrosomal protein 135
chr2_+_69013379 0.14 ENST00000409349.7
ANTXR cell adhesion molecule 1
chr4_-_170089930 0.14 ENST00000337664.9
aminoadipate aminotransferase
chr9_-_35096557 0.14 ENST00000378617.4
ENST00000361778.6
phosphatidylinositol glycan anchor biosynthesis class O
chr7_+_150824603 0.14 ENST00000493429.5
amine oxidase copper containing 1
chr6_+_106360668 0.14 ENST00000633556.3
crystallin beta-gamma domain containing 1
chr2_+_69013337 0.14 ENST00000463335.2
ANTXR cell adhesion molecule 1
chr4_-_170090153 0.14 ENST00000509167.5
ENST00000353187.6
ENST00000507375.5
ENST00000515480.5
aminoadipate aminotransferase
chr20_+_31514410 0.14 ENST00000335574.10
ENST00000340852.9
ENST00000398174.9
ENST00000466766.2
ENST00000498035.5
ENST00000344042.5
histocompatibility minor 13
chr11_-_113773668 0.13 ENST00000200135.8
zw10 kinetochore protein
chr16_-_88785210 0.13 ENST00000301015.14
piezo type mechanosensitive ion channel component 1
chr1_+_151156627 0.13 ENST00000368910.4
TNF alpha induced protein 8 like 2
chr4_+_55346349 0.13 ENST00000505210.1
steroid 5 alpha-reductase 3
chr22_-_22559073 0.13 ENST00000420709.5
ENST00000398741.5
PRAME nuclear receptor transcriptional regulator
chr1_+_28518136 0.13 ENST00000373832.5
ENST00000373831.7
regulator of chromosome condensation 1
chr13_-_36999295 0.13 ENST00000679673.1
ENST00000679572.1
ENST00000239891.4
ENST00000681763.1
ENST00000680671.1
ENST00000680012.1
ENST00000679837.1
ENST00000443765.6
ALG5 dolichyl-phosphate beta-glucosyltransferase
chr17_-_74923222 0.13 ENST00000614341.5
USH1 protein network component sans
chr6_-_44257279 0.13 ENST00000619636.4
solute carrier family 35 member B2
chr10_+_13161543 0.13 ENST00000378714.8
ENST00000479669.5
ENST00000484800.6
minichromosome maintenance 10 replication initiation factor
chr15_+_45430579 0.13 ENST00000558435.5
ENST00000344300.3
ENST00000396650.7
chromosome 15 open reading frame 48
chr12_-_51270175 0.13 ENST00000604188.1
ENST00000398453.7
small cell adhesion glycoprotein
chr1_-_6554501 0.13 ENST00000377705.6
nucleolar protein 9
chr6_-_44257494 0.12 ENST00000393812.4
ENST00000393810.5
ENST00000538577.5
ENST00000537814.2
solute carrier family 35 member B2
chr9_-_114682172 0.12 ENST00000436752.3
testis expressed 48
chr10_-_48524236 0.12 ENST00000374170.5
Rho GTPase activating protein 22
chr5_+_176448363 0.12 ENST00000261942.7
Fas associated factor family member 2
chr12_+_51424965 0.12 ENST00000514353.7
solute carrier family 4 member 8
chrX_+_47193796 0.12 ENST00000442035.5
ENST00000335972.11
ENST00000457753.5
ubiquitin like modifier activating enzyme 1
chr19_+_4791710 0.12 ENST00000269856.5
fem-1 homolog A
chr2_+_90069662 0.12 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr16_+_16232516 0.12 ENST00000399336.9
ENST00000678538.1
ENST00000678192.1
ENST00000677777.1
ENST00000677260.1
ENST00000676550.1
ENST00000263012.10
NODAL modulator 3
chrX_+_149881141 0.12 ENST00000535454.5
ENST00000542674.5
ENST00000286482.6
MAGE family member A8
chr19_+_1266653 0.12 ENST00000586472.5
ENST00000589266.5
cold inducible RNA binding protein
chr3_+_141876124 0.12 ENST00000475483.5
ATPase Na+/K+ transporting subunit beta 3
chr17_+_7688427 0.12 ENST00000396463.7
ENST00000534050.5
WD repeat containing antisense to TP53
chr14_-_69574845 0.12 ENST00000599174.3
coiled-coil domain containing 177
chr11_+_120240135 0.11 ENST00000543440.7
POU class 2 homeobox 3
chr5_-_147453888 0.11 ENST00000398514.7
dihydropyrimidinase like 3
chr9_+_124853417 0.11 ENST00000613760.4
ENST00000618744.4
ENST00000373574.2
WD repeat domain 38
chr9_-_114682061 0.11 ENST00000612244.5
testis expressed 48
chr11_+_44095655 0.11 ENST00000684533.1
ENST00000683000.1
ENST00000395673.8
ENST00000682359.1
ENST00000533608.7
exostosin glycosyltransferase 2
chr17_-_63446260 0.11 ENST00000448884.6
ENST00000582297.5
ENST00000360793.8
ENST00000582034.5
ENST00000578072.1
cytochrome b561
chr16_+_14833713 0.11 ENST00000287667.12
ENST00000620755.4
ENST00000610363.4
NODAL modulator 1
chr8_-_144444406 0.11 ENST00000409379.8
tonsoku like, DNA repair protein
chr11_+_119206298 0.11 ENST00000634586.1
ENST00000634840.1
ENST00000264033.6
ENST00000637974.1
Cbl proto-oncogene
chr14_+_21868822 0.11 ENST00000390436.2
T cell receptor alpha variable 13-1
chr13_+_32586443 0.11 ENST00000315596.15
PDS5 cohesin associated factor B
chr8_-_144326842 0.11 ENST00000528718.6
diacylglycerol O-acyltransferase 1
chr11_+_44095710 0.11 ENST00000358681.8
ENST00000343631.4
ENST00000682711.1
exostosin glycosyltransferase 2
chr15_+_74782069 0.11 ENST00000220003.14
ENST00000439220.6
C-terminal Src kinase
chr8_-_89984231 0.11 ENST00000517337.1
ENST00000409330.5
nibrin
chr22_+_22380766 0.11 ENST00000390297.3
immunoglobulin lambda variable 1-44
chr5_-_141618914 0.11 ENST00000518047.5
diaphanous related formin 1
chr8_-_89984609 0.10 ENST00000519426.5
ENST00000265433.8
nibrin
chr9_+_4662281 0.10 ENST00000381883.5
phospholipid phosphatase 6
chr7_+_156949704 0.10 ENST00000275820.4
nucleolar protein with MIF4G domain 1
chr5_+_146447304 0.10 ENST00000296702.9
ENST00000394421.7
ENST00000679501.2
transcription elongation regulator 1
chr2_+_27086738 0.10 ENST00000260599.10
ENST00000260598.10
ENST00000429697.1
ketohexokinase
chr5_-_141619049 0.10 ENST00000647433.1
ENST00000253811.10
ENST00000389057.9
ENST00000398557.8
diaphanous related formin 1
chr19_-_45815228 0.10 ENST00000597055.1
radial spoke head 6 homolog A
chr11_-_130916437 0.10 ENST00000533214.1
ENST00000528555.5
ENST00000530356.5
ENST00000265909.9
sorting nexin 19
chr19_+_47349298 0.10 ENST00000328771.9
DExH-box helicase 34
chr5_-_141618957 0.10 ENST00000389054.8
diaphanous related formin 1
chr10_-_75235917 0.10 ENST00000469299.1
ENST00000372538.8
catechol-O-methyltransferase domain containing 1
chr22_-_22559229 0.10 ENST00000405655.8
ENST00000406503.1
ENST00000439106.5
ENST00000402697.5
ENST00000543184.5
ENST00000398743.6
PRAME nuclear receptor transcriptional regulator
chr3_-_47475811 0.10 ENST00000265565.10
ENST00000428413.5
SREBF chaperone
chr16_-_66830903 0.10 ENST00000566336.5
ENST00000394074.6
ENST00000563185.6
ENST00000359087.8
ENST00000290810.8
ENST00000379463.6
ENST00000565535.5
NEDD8 activating enzyme E1 subunit 1
chr1_+_171485520 0.10 ENST00000647382.2
ENST00000392078.7
ENST00000367742.7
ENST00000338920.8
proline rich coiled-coil 2C
chr8_-_144326908 0.09 ENST00000332324.5
diacylglycerol O-acyltransferase 1
chr17_+_7717727 0.09 ENST00000570791.5
dynein axonemal heavy chain 2
chr6_-_138987640 0.09 ENST00000529597.5
ENST00000415951.6
ENST00000367663.8
ENST00000409812.6
RALBP1 associated Eps domain containing 1
chr2_+_102473219 0.09 ENST00000295269.5
solute carrier family 9 member A4
chr2_+_231056845 0.09 ENST00000677230.1
ENST00000677259.1
ENST00000677180.1
ENST00000409643.6
ENST00000619128.5
ENST00000678679.1
ENST00000676740.1
ENST00000308696.11
ENST00000440838.5
ENST00000373635.9
proteasome 26S subunit, non-ATPase 1
chr6_-_138988241 0.09 ENST00000450536.7
ENST00000626459.2
ENST00000258062.9
RALBP1 associated Eps domain containing 1
chr11_+_66258467 0.09 ENST00000394066.6
kinesin light chain 2
chr14_+_21841182 0.09 ENST00000390433.1
T cell receptor alpha variable 12-1
chr1_-_113905020 0.09 ENST00000432415.5
ENST00000369571.2
ENST00000256658.8
ENST00000369564.5
adaptor related protein complex 4 subunit beta 1
chr4_+_127965429 0.09 ENST00000513371.1
ENST00000611882.1
abhydrolase domain containing 18
chr15_+_31978056 0.09 ENST00000637183.1
cholinergic receptor nicotinic alpha 7 subunit
chr12_-_120325936 0.09 ENST00000549767.1
phospholipase A2 group IB
chr2_+_69013170 0.09 ENST00000303714.9
ANTXR cell adhesion molecule 1
chr17_+_21692523 0.09 ENST00000567955.3
potassium inwardly rectifying channel subfamily J member 18
chr11_+_46347425 0.08 ENST00000527911.5
diacylglycerol kinase zeta
chr11_-_61816985 0.08 ENST00000350997.12
fatty acid desaturase 1
chr14_+_21918161 0.08 ENST00000390439.2
T cell receptor alpha variable 13-2
chrX_+_77910656 0.08 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr10_-_90857680 0.08 ENST00000277874.10
ENST00000371719.2
5-hydroxytryptamine receptor 7
chr17_+_39980799 0.08 ENST00000264639.9
proteasome 26S subunit, non-ATPase 3
chr17_-_37359076 0.08 ENST00000621960.1
ENST00000614428.4
ENST00000614789.4
acetyl-CoA carboxylase alpha
chr14_+_21887848 0.08 ENST00000390437.2
T cell receptor alpha variable 12-2
chr2_-_218292496 0.08 ENST00000258412.8
ENST00000445635.5
ENST00000413976.1
transmembrane BAX inhibitor motif containing 1
chr1_+_27392612 0.08 ENST00000374024.4
G protein-coupled receptor 3
chr11_-_18106019 0.08 ENST00000532452.5
ENST00000530180.1
ENST00000524803.6
ENST00000300013.8
ENST00000529318.5
serum amyloid A like 1
chr18_+_13824149 0.08 ENST00000589410.2
melanocortin 5 receptor
chr19_-_48993300 0.08 ENST00000323798.8
ENST00000263276.6
glycogen synthase 1
chr1_-_113904789 0.08 ENST00000369569.6
ENST00000369567.5
adaptor related protein complex 4 subunit beta 1
chr14_+_51651901 0.08 ENST00000344768.10
FERM domain containing 6
chr1_+_113905290 0.08 ENST00000650450.2
DNA cross-link repair 1B
chr16_-_22001098 0.08 ENST00000537222.6
ENST00000424898.3
PDZ domain containing 9
chr8_-_42501224 0.08 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr18_-_50195138 0.08 ENST00000285039.12
myosin VB
chr15_+_73873604 0.08 ENST00000535547.6
ENST00000562056.1
TBC1 domain family member 21
chr9_+_136844415 0.08 ENST00000436881.2
apical junction component 1 homolog
chr5_+_140821598 0.08 ENST00000614258.1
ENST00000529859.2
ENST00000529619.5
protocadherin alpha 5
chr7_-_123534559 0.08 ENST00000324698.11
IQ motif and ubiquitin domain containing
chr22_+_22357739 0.08 ENST00000390294.2
immunoglobulin lambda variable 1-47
chrX_+_50204753 0.08 ENST00000376042.6
cyclin B3
chr1_-_39901861 0.08 ENST00000372816.3
ENST00000372815.1
MYCL proto-oncogene, bHLH transcription factor
chrX_-_46759055 0.08 ENST00000328306.4
ENST00000616978.5
solute carrier family 9 member A7
chr12_+_13044371 0.08 ENST00000197268.13
family with sequence similarity 234 member B
chr1_+_151070740 0.07 ENST00000368918.8
GA binding protein transcription factor subunit beta 2
chr19_-_57889004 0.07 ENST00000597832.5
ENST00000435989.7
ENST00000614383.1
zinc finger protein 814
chr2_+_11133119 0.07 ENST00000381585.8
ENST00000405022.3
chromosome 2 open reading frame 50
chr9_-_136363695 0.07 ENST00000371739.3
ENST00000371738.4
DNL-type zinc finger
chr14_-_49852760 0.07 ENST00000555970.5
ENST00000298310.10
ENST00000554626.5
ENST00000556672.1
nuclear export mediator factor
chr6_-_32838727 0.07 ENST00000652259.1
ENST00000374897.4
ENST00000620123.4
ENST00000452392.2
transporter 2, ATP binding cassette subfamily B member
novel protein, TAP2-HLA-DOB readthrough
chr4_-_127965930 0.07 ENST00000641447.1
ENST00000296468.8
ENST00000641134.1
ENST00000641147.1
ENST00000641178.1
major facilitator superfamily domain containing 8
chr17_+_67717902 0.07 ENST00000581106.5
ENST00000253247.9
nucleolar protein 11
chr22_+_22409755 0.07 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr16_+_53054973 0.07 ENST00000447540.6
ENST00000615216.4
ENST00000566029.5
chromodomain helicase DNA binding protein 9
chr15_-_34969688 0.07 ENST00000156471.10
aquarius intron-binding spliceosomal factor
chr1_+_28518266 0.07 ENST00000411533.5
regulator of chromosome condensation 1
chr15_+_91853690 0.07 ENST00000318445.11
solute carrier organic anion transporter family member 3A1
chr2_+_151410090 0.07 ENST00000430328.6
replication timing regulatory factor 1
chr1_+_113905156 0.07 ENST00000650596.1
DNA cross-link repair 1B
chr11_-_36510232 0.07 ENST00000348124.5
ENST00000526995.6
TNF receptor associated factor 6
chr18_-_59697637 0.07 ENST00000649564.1
collagen and calcium binding EGF domains 1
chr8_+_100158029 0.07 ENST00000251809.4
sperm associated antigen 1
chr17_-_75904873 0.07 ENST00000309352.4
mitochondrial ribosomal protein L38
chr16_-_81198766 0.07 ENST00000526632.5
polycystin 1 like 2 (gene/pseudogene)
chr1_+_209938169 0.07 ENST00000367019.5
ENST00000537238.5
ENST00000637265.1
synaptotagmin 14
chr2_-_74482914 0.07 ENST00000290418.4
ENST00000393965.8
coiled-coil domain containing 142
chr3_-_50303565 0.07 ENST00000266031.8
ENST00000395143.6
ENST00000457214.6
ENST00000447605.2
ENST00000395144.7
ENST00000418723.1
hyaluronidase 1
chr14_+_21768482 0.07 ENST00000390428.3
T cell receptor alpha variable 6
chr4_-_127965133 0.07 ENST00000641558.1
ENST00000641590.1
ENST00000641503.1
ENST00000641482.1
ENST00000641743.1
ENST00000641369.1
ENST00000641949.1
ENST00000641695.1
ENST00000641509.1
ENST00000641243.1
ENST00000641686.2
ENST00000641690.1
ENST00000641228.1
ENST00000642042.1
major facilitator superfamily domain containing 8
chr4_+_153344671 0.07 ENST00000240488.8
meiotic nuclear divisions 1
chr4_-_127965204 0.07 ENST00000513559.6
ENST00000641186.1
ENST00000641393.1
major facilitator superfamily domain containing 8
chr14_+_51651858 0.07 ENST00000395718.6
FERM domain containing 6
chr1_+_209938207 0.07 ENST00000472886.5
synaptotagmin 14
chr11_-_117232033 0.07 ENST00000524507.6
ENST00000320934.8
ENST00000532301.5
ENST00000676339.1
ENST00000540028.5
proprotein convertase subtilisin/kexin type 7
chr14_-_54441325 0.07 ENST00000556113.1
ENST00000553660.5
ENST00000216416.9
ENST00000395573.8
ENST00000557690.5
cornichon family AMPA receptor auxiliary protein 1
chr2_-_89160329 0.07 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr17_-_36534927 0.07 ENST00000610930.4
myosin XIX
chr16_-_23557331 0.06 ENST00000563232.1
ENST00000449606.7
glutamyl-tRNA synthetase 2, mitochondrial
chr2_+_90021567 0.06 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr3_-_142888896 0.06 ENST00000485766.1
procollagen C-endopeptidase enhancer 2
chr4_-_7042931 0.06 ENST00000310085.6
coiled-coil domain containing 96
chr18_-_59697220 0.06 ENST00000650467.1
ENST00000439986.9
collagen and calcium binding EGF domains 1
chr1_+_92029971 0.06 ENST00000370383.5
epoxide hydrolase 4
chr10_+_102132994 0.06 ENST00000413464.6
ENST00000278070.7
PPARG related coactivator 1
chr20_+_45363114 0.06 ENST00000426004.5
ENST00000243918.10
SYS1 golgi trafficking protein
chr1_-_226408045 0.06 ENST00000366794.10
ENST00000677203.1
poly(ADP-ribose) polymerase 1
chr11_+_120511708 0.06 ENST00000638419.1
ENST00000527524.8
glutamate ionotropic receptor kainate type subunit 4
chr2_+_148978361 0.06 ENST00000678720.1
ENST00000678856.1
ENST00000677080.1
kinesin family member 5C
chr1_+_15153698 0.06 ENST00000400796.7
ENST00000376008.3
ENST00000434578.6
transmembrane protein 51
chr2_-_165203870 0.06 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
sodium voltage-gated channel alpha subunit 3

Network of associatons between targets according to the STRING database.

First level regulatory network of RAD21_SMC3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0031445 regulation of heterochromatin assembly(GO:0031445) positive regulation of heterochromatin assembly(GO:0031453)
0.1 0.4 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.1 0.7 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.5 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.3 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 0.3 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.3 GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.2 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.3 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.1 GO:0046967 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) cytosol to ER transport(GO:0046967)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0061184 positive regulation of dermatome development(GO:0061184)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.3 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.0 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.0 0.1 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.2 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0019230 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283) proprioception(GO:0019230)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.0 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.0 GO:1904588 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.0 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.0 GO:0051463 negative regulation of cortisol secretion(GO:0051463)
0.0 0.0 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.0 GO:0046108 uridine metabolic process(GO:0046108)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.4 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.7 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0001940 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.3 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.3 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 1.3 GO:0043495 protein anchor(GO:0043495)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.2 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.3 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0070704 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.1 GO:0004008 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.0 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.0 GO:0004850 uridine phosphorylase activity(GO:0004850)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation